Data / Nonprofits / Illinois / Chicago
Nonprofits in Chicago, IL: 19,601 registered with the IRS
19,601 nonprofits are registered with the IRS in Chicago, IL, 16,207 of them 501(c)(3) charities; the 5,347 that report revenue took in $78.00 billion. The largest by revenue: Northwestern Memorial Healthcare ($11.24 billion), University of Chicago ($5.62 billion), Central States Southeast & Southwest Areas Health & Welfare F ($5.47 billion). Most common causes: religion-related (1,986), education (1,843), philanthropy, voluntarism and grantmaking foundations (1,565).
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The 500 largest by revenue
| Organization | Category | Type | Since | Revenue | Assets | Filing |
|---|---|---|---|---|---|---|
| Northwestern Memorial Healthcare | Health care | 501(c)(3) | 2011 | $11.24 billion | $15.49 billion | 2025-08 |
| University of Chicago | Education | 501(c)(3) | 1951 | $5.62 billion | $15.81 billion | 2025-06 |
| Central States Southeast & Southwest Areas Health & Welfare F | 501(c)(9) | 1959 | $5.47 billion | $16.59 billion | 2024-12 | |
| Feeding America | Food, agriculture and nutrition | 501(c)(3) | 1990 | $5.00 billion | $572.5 million | 2025-06 |
| University of Chicago Medical Center | Health care | 501(c)(3) | 1987 | $3.57 billion | $5.27 billion | 2025-06 |
| Northwestern Memorial Healthcare | Health care | 501(c)(3) | 2011 | $2.77 billion | $16.79 billion | 2025-08 |
| Rush University Medical Center | Health care | 501(c)(3) | 1960 | $2.76 billion | $5.23 billion | 2025-06 |
| The Chicago Community Trust | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1951 | $2.14 billion | $7.13 billion | 2025-09 |
| Alliant Credit Union | Public and societal benefit | 501(c)(14) | 1964 | $1.27 billion | $19.54 billion | 2024-12 |
| The Johnson & Johnson Voluntary Employee Benefit Trust | 501(c)(9) | 1972 | $1.20 billion | $39.7 million | 2025-12 | |
| Loyola University of Chicago | Education | 501(c)(3) | 2007 | $1.06 billion | $2.66 billion | 2025-06 |
| Accenture United States Benefit | Mutual and membership benefit | 501(c)(9) | 2002 | $1.02 billion | $132.5 million | 2025-08 |
| Depaul University | Education | 501(c)(3) | 1952 | $966.9 million | $2.03 billion | 2025-06 |
| Blue Cross Blue Shield Association | Health care | 501(c)(4) | 1958 | $862.7 million | $1.25 billion | 2024-12 |
| American Medical Association | 501(c)(6) | 1946 | $546.2 million | $1.48 billion | 2024-12 | |
| United Airlines Employee Sick Leave Trust | Mutual and membership benefit | 501(c)(9) | 2016 | $539.7 million | $61.6 million | 2024-12 |
| Rehabilitation Institute of Chicago | Health care | 501(c)(3) | 1954 | $481.4 million | $1.32 billion | 2025-08 |
| Mount Sinai Hospital Medical Center | Health care | 501(c)(3) | 1926 | $481.3 million | $341.4 million | 2025-06 |
| Rush Medical Group | Human services | 501(c)(3) | 2024 | $475 million | $146.9 million | 2025-06 |
| Art Institute of Chicago | Education | 501(c)(3) | 1925 | $464.4 million | $2.19 billion | 2025-06 |
| Alzheimers Disease and Related Disorders Association Inc | Diseases, disorders and medical disciplines | 501(c)(3) | 1985 | $457.2 million | $523.7 million | 2025-06 |
| Illinois Institute of Technology | Education | 501(c)(3) | 1941 | $448.5 million | $833.3 million | 2025-05 |
| Lurie Childrens Medical Group Inc | Health care | 501(c)(3) | 1988 | $434 million | $48 million | 2025-08 |
| Chicago District Council of Carpenters Welfare Fund | 501(c)(9) | 1956 | $432.8 million | $1.36 billion | 2025-06 | |
| National Opinion Research Center | Social science | 501(c)(3) | 1943 | $397.2 million | $225 million | 2024-12 |
| National Association of Realtors | 501(c)(6) | 1934 | $360.8 million | $1.08 billion | 2024-12 | |
| Exelon Corporation Employees Benefit Trust | 501(c)(9) | 1973 | $345.7 million | $62 million | 2024-12 | |
| International Fellowship of Christians & Jews | 501(c)(3) | 1983 | $318.2 million | $233 million | 2024-12 | |
| Jewish Federation of Metropolitan Chicago | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1949 | $284.6 million | $1.12 billion | 2025-06 |
| Rush System for Health | Health care | 501(c)(3) | 1996 | $283.2 million | $82 million | 2025-06 |
| United States Soccer Federation Inc | Recreation and sports | 501(c)(3) | 1984 | $268.1 million | $458.8 million | 2025-03 |
| Columbia College Chicago | Education | 501(c)(3) | 1943 | $267.6 million | $429.7 million | 2025-08 |
| Greater Chicago Food Depository | Food, agriculture and nutrition | 501(c)(3) | 1978 | $241.6 million | $216 million | 2025-06 |
| American Dental Association | 501(c)(6) | 1951 | $237.1 million | $286.9 million | 2024-12 | |
| Caterpillar Inc Group Insurance Master Trust Agreement | 501(c)(9) | 1971 | $235.2 million | $127.9 million | 2025-12 | |
| Noble Network of Charter Schools | Education | 501(c)(3) | 1999 | $230.3 million | $259.2 million | 2025-06 |
| Hyatt Corporation Welfare Benefit Trust | 501(c)(9) | 1989 | $221.7 million | $5.4 million | 2025-12 | |
| Howard Brown Health Center | 501(c)(3) | 1978 | $217.5 million | $187.8 million | 2025-06 | |
| The Barack Obama Foundation | Arts, culture and humanities | 501(c)(3) | 2014 | $209.8 million | $1.11 billion | 2024-12 |
| Kraft Foods North America Inc Group Benefit Trust I | 501(c)(9) | 1988 | $205.5 million | $14.9 million | 2024-12 | |
| National Council of Young Mens Christian Assns of the USA | Human services | 501(c)(3) | 1983 | $198.4 million | $260.5 million | 2024-12 |
| Pipe Fitters Welfare Fund Local 597 | 501(c)(9) | 1965 | $195.8 million | $342.1 million | 2024-12 | |
| United Airlines Pilot Retiree Health Account Plan | Mutual and membership benefit | 501(c)(9) | 2015 | $191.2 million | $953 million | 2024-12 |
| Misericordia Home | Human services | 501(c)(3) | 1946 | $182.4 million | $363.7 million | 2025-06 |
| Metropolitan Family Services | Human services | 501(c)(3) | 1952 | $180.2 million | $142.1 million | 2025-06 |
| Institute for the International Education of Students | Education | 501(c)(3) | 1960 | $178.5 million | $158.2 million | 2025-06 |
| American College of Surgeons | Education | 501(c)(3) | 1939 | $177.5 million | $773 million | 2025-06 |
| Catholic Charities of the Archdiocese of Chicago | 501(c)(3) | 1946 | $174.7 million | $211.6 million | 2025-06 | |
| Community and Economic Development Association of Cook County Inc | Community improvement and capacity building | 501(c)(3) | 1966 | $168.1 million | $45.2 million | 2025-06 |
| American Bar Association | 501(c)(6) | 1994 | $166.2 million | $307.7 million | 2025-08 | |
| Humboldt Park Health | Health care | 501(c)(3) | 1937 | $166.1 million | $155.8 million | 2025-09 |
| Access Community Health Network | Health care | 501(c)(3) | 1985 | $165.6 million | $81.3 million | 2024-12 |
| Thorek Memorial Hospital | Health care | 501(c)(3) | 1939 | $161 million | $704.8 million | 2025-06 |
| Saint Anthony Hospital | Health care | 501(c)(3) | 1946 | $159 million | $131.9 million | 2025-06 |
| St Bernard Hospital | Health care | 501(c)(3) | 1946 | $155 million | $75.3 million | 2025-12 |
| National Futures Association | 501(c)(6) | 1978 | $154.9 million | $252 million | 2025-06 | |
| Jewish United Fund of Metropolitan Chicago | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1950 | $154.2 million | $261.5 million | 2025-06 |
| Seiu Healthcare Il Home Care & Child Care Fund | Mutual and membership benefit | 501(c)(9) | 2009 | $150 million | $301 million | 2025-04 |
| American Hospital Association Inc | 501(c)(6) | 1950 | $146.7 million | $435.3 million | 2024-12 | |
| Roosevelt University | 501(c)(3) | 1945 | $145.7 million | $396 million | 2025-08 | |
| Seiu Local 1 & Participating Employers Health Trust | 501(c)(9) | 1975 | $145.6 million | $171.7 million | 2025-09 | |
| The Chicago School - California Inc | 501(c)(3) | 2010 | $144.2 million | $315.5 million | 2025-05 | |
| National Council of State Boards of Nursing Inc | Health care | 501(c)(3) | 1987 | $144 million | $325.7 million | 2025-09 |
| The Thresholds | 501(c)(3) | 1965 | $137.6 million | $104.6 million | 2025-06 | |
| Holy Cross Hospital | Health care | 501(c)(3) | 1946 | $137.3 million | $95.1 million | 2025-06 |
| Saint Xavier University | Education | 501(c)(3) | 1946 | $136.7 million | $178.5 million | 2025-06 |
| Ronald McDonald House Global | Health care | 501(c)(3) | 1977 | $134.5 million | $328.9 million | 2025-12 |
| McGaw Medical Center of Northwestern University | 501(c)(3) | 1971 | $134.4 million | $24.3 million | 2025-08 | |
| Chicago Charter School Foundation | Education | 501(c)(3) | 1999 | $134 million | $115.1 million | 2025-06 |
| Erie Family Health Center Inc | Health care | 501(c)(3) | 1982 | $132.3 million | $120.7 million | 2025-06 |
| Moody Bible Institute of Chicago | Education | 501(c)(3) | 1933 | $129.6 million | $571.8 million | 2025-06 |
| Chicago Symphony Orchestra | Arts, culture and humanities | 501(c)(3) | 1927 | $125.9 million | $647 million | 2025-06 |
| Acero Charter Schools Inc | 501(c)(3) | 2001 | $119.1 million | $110.3 million | 2025-06 | |
| American Lung Association | Diseases, disorders and medical disciplines | 501(c)(3) | 1944 | $118.7 million | $225.7 million | 2025-06 |
| Gateway Foundation Inc | Mental health and crisis intervention | 501(c)(3) | 1968 | $118.2 million | $45.4 million | 2025-06 |
| National Board of YMCA Employee Benefit Trust | 501(c)(9) | 1983 | $117.7 million | $20.8 million | 2025-12 | |
| Start Early | 501(c)(3) | 1982 | $115.2 million | $124.4 million | 2025-06 | |
| Field Museum of Natural History | Arts, culture and humanities | 501(c)(3) | 1945 | $114.8 million | $932.9 million | 2024-12 |
| Sinai Health System | Health care | 501(c)(3) | 1982 | $112.5 million | $229.7 million | 2025-06 |
| United Brotherhood of Carpenters & Joiners of America | 501(c)(5) | 1940 | $110 million | $262.1 million | 2025-06 | |
| Robert R McCormick Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1990 | $105.3 million | $1.75 billion | 2024-12 |
| Mount Sinai Community Foundation | 501(c)(3) | 1984 | $105.1 million | $9.5 million | 2025-06 | |
| North Park University | Education | 501(c)(3) | 1975 | $102.6 million | $334 million | 2025-06 |
| American Bar Association Fund for Justice and Education | Crime and legal-related | 501(c)(3) | 1963 | $102.4 million | $42.4 million | 2025-08 |
| Shedd Aquarium Society | Animal-related | 501(c)(3) | 1932 | $102 million | $780.1 million | 2024-12 |
| Lawndale Christian Health Center | 501(c)(3) | 1984 | $97.6 million | $148.5 million | 2025-06 | |
| Union Health Service Inc | Health care | 501(c)(3) | 1984 | $96.1 million | $74.1 million | 2025-12 |
| Jackson Park Hospital Foundation | Health care | 501(c)(3) | 1962 | $95.8 million | $142.5 million | 2025-03 |
| La Rabida Childrens Hospital | Health care | 501(c)(3) | 1932 | $93.4 million | $302.3 million | 2025-06 |
| Envision Unlimited | Human services | 501(c)(3) | 1965 | $92.6 million | $34.1 million | 2025-06 |
| Plumbers Welfare Fund-130 U A | 501(c)(9) | 1952 | $92.6 million | $176 million | 2025-05 | |
| International Union of Operating Engineers Local 399 | 501(c)(9) | 1994 | $89.9 million | $111.5 million | 2025-05 | |
| Accreditation Council for Graduate Medical Education | Education | 501(c)(3) | 2001 | $88.5 million | $132.4 million | 2024-12 |
| One Hope United | Human services | 501(c)(3) | 2015 | $87.7 million | $69.6 million | 2025-06 |
| Lawndale Educational and Regional Network Charter School | Education | 501(c)(3) | 2001 | $87.4 million | $106.2 million | 2025-06 |
| Childrens Home & Aid Society of Illinois | Human services | 501(c)(3) | 1933 | $85.7 million | $60.2 million | 2025-06 |
| Cna Employees Health Plan | 501(c)(9) | 1988 | $85.6 million | $6.8 million | 2024-12 | |
| National Equity Fund Inc | 501(c)(4) | $85.5 million | $122.2 million | 2024-12 | ||
| Kraft Foods Global Inc Retiree Health and Life Benefit Trust | Mutual and membership benefit | 501(c)(9) | 2013 | $82.3 million | $791.3 million | 2024-12 |
| Development Now for Chicago | Community improvement and capacity building | 501(c)(6) | 2022 | $81.5 million | $9 million | 2024-11 |
| Crown Family Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1985 | $81 million | $530.8 million | 2025-06 |
| Lyric Opera of Chicago | Arts, culture and humanities | 501(c)(3) | 1957 | $80.8 million | $285.4 million | 2025-06 |
| YMCA of Metropolitan Chicago | Human services | 501(c)(3) | 1941 | $80.5 million | $176.4 million | 2024-12 |
| Nef Community Investments Inc | Housing and shelter | 501(c)(4) | 2005 | $80.4 million | $65.1 million | 2024-12 |
| TCS Education System | Education | 501(c)(3) | 2010 | $80 million | $130.5 million | 2025-05 |
| Easter Seals Metropolitan Chicago Inc | Health care | 501(c)(3) | 2001 | $78.4 million | $53.9 million | 2025-06 |
| American Property Casualty Insurance Association | Community improvement and capacity building | 501(c)(6) | 2005 | $77.8 million | $181.6 million | 2024-12 |
| Chicago Cook Workforce Partnership | Education | 501(c)(3) | 1997 | $77.7 million | $23.4 million | 2025-06 |
| Navy Pier Inc | Arts, culture and humanities | 501(c)(3) | 2011 | $77.1 million | $183 million | 2025-12 |
| Loretto Hospital | Health care | 501(c)(3) | 1992 | $75.6 million | $48.5 million | 2025-06 |
| Ucan | Human services | 501(c)(3) | 1939 | $74.6 million | $80.9 million | 2025-06 |
| Healthcare Information and Management Systems Society | Community improvement and capacity building | 501(c)(6) | 2001 | $74.5 million | $22.9 million | 2022-12 |
| Ann & Robert H Lurie Childrens Hospital of Chicago Foundation | Health care | 501(c)(3) | 1987 | $72.5 million | $927,211 | 2025-08 |
| Ada S McKinley Community Services Inc | Human services | 501(c)(3) | 1950 | $69.9 million | $29.6 million | 2025-06 |
| Esperanza Health Centers | Health care | 501(c)(3) | 2005 | $69.1 million | $60.2 million | 2025-06 |
| Heartland Human Care Services Inc | Human services | 501(c)(3) | 1996 | $68.8 million | $26.5 million | 2023-06 |
| Society of Actuaries Professional Association | Community improvement and capacity building | 501(c)(6) | 2019 | $68.3 million | $88.9 million | 2024-12 |
| Roseland Community Hospital | Health care | 501(c)(3) | 1941 | $68.2 million | $24.5 million | 2025-03 |
| Alpha Kappa Alpha Sorority Inc | 501(c)(7) | 1983 | $67.6 million | $56.5 million | 2025-12 | |
| Kenneth C Griffin Museum of Science and Industry | Arts, culture and humanities | 501(c)(3) | 1938 | $66.4 million | $433 million | 2024-12 |
| Ucm Medical Group Inc | Health care | 501(c)(3) | 2020 | $66.1 million | $94.9 million | 2025-06 |
| Trilogy Inc | 501(c)(3) | 1972 | $66.1 million | $32 million | 2025-06 | |
| Friend Family Health Center Inc | Health care | 501(c)(3) | 1997 | $65.5 million | $80.3 million | 2025-06 |
| Stanley Manne Childrens Research Institute | Medical research | 501(c)(3) | 1987 | $65.1 million | $127.6 million | 2025-08 |
| Muscular Dystrophy Association | Diseases, disorders and medical disciplines | 501(c)(3) | 1952 | $64.2 million | $50.9 million | 2025-12 |
| Ukraine-Moldova American Enterprise Fund | International, foreign affairs and national security | 501(c)(3) | 1995 | $63 million | $285.9 million | 2025-09 |
| Prosight Financial Association | 501(c)(6) | 1978 | $63 million | $102.5 million | 2025-09 | |
| Council for Jewish Elderly | Human services | 501(c)(3) | 1972 | $62.7 million | $40.2 million | 2025-06 |
| Iff | Community improvement and capacity building | 501(c)(3) | 1990 | $62.5 million | $828.3 million | 2025-12 |
| Planned Parenthood of Illinois | Health care | 501(c)(3) | 1948 | $62.3 million | $95.4 million | 2025-06 |
| Elks National Foundation Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2009 | $61.8 million | $954.1 million | 2026-03 |
| Latin School of Chicago | Education | 501(c)(3) | 1954 | $61.1 million | $163.4 million | 2025-06 |
| Elevate Energy | Environment | 501(c)(3) | 2013 | $60.9 million | $58.3 million | 2024-12 |
| Illinois Action for Children | 501(c)(3) | 1972 | $60.6 million | $21.4 million | 2025-06 | |
| The Chicago Lighthouse for People Who Are Blind Or Visually Impaired | Human services | 501(c)(3) | 2021 | $60.1 million | $53 million | 2025-06 |
| Distinctive Schools of Illinois | Education | 501(c)(3) | 2015 | $60.1 million | $3.5 million | 2025-06 |
| Misericordia Foundation | Human services | 501(c)(3) | 1974 | $59.4 million | $837.5 million | 2025-06 |
| Benevolent & Protective Order of Elks of the USA | 501(c)(8) | 1951 | $57.4 million | $142.6 million | 2025-05 | |
| Rush University System for Health Self-Insurance Trust | 501(c)(3) | 1979 | $57.3 million | $203 million | 2024-12 | |
| Kipp Chicago Schools | Education | 501(c)(3) | 2004 | $56.8 million | $12.4 million | 2025-06 |
| Illinois Coalition for Immigrant and Refugee Rights | Civil rights, social action and advocacy | 501(c)(3) | 1993 | $56.3 million | $28.8 million | 2025-06 |
| Francis W Parker School | Education | 501(c)(3) | 1932 | $56.2 million | $193.3 million | 2025-06 |
| All Chicago Making Homelessness History | Housing and shelter | 501(c)(3) | 1999 | $54.9 million | $23.6 million | 2024-12 |
| Chicago Commons Association | Human services | 501(c)(3) | 1985 | $53.9 million | $22.8 million | 2025-06 |
| Big Shoulders Fund | Education | 501(c)(3) | 1987 | $53.2 million | $152.1 million | 2025-06 |
| Schwab Rehabilitation Hosptial and Care Network | Health care | 501(c)(3) | 1939 | $52.7 million | $88.7 million | 2025-06 |
| Opportunity International Inc | International, foreign affairs and national security | 501(c)(3) | 1973 | $51.1 million | $83.2 million | 2025-09 |
| South Shore Hospital Corporation | Health care | 501(c)(3) | 1977 | $51 million | $17.6 million | 2024-12 |
| Youth Connection Charter School | Education | 501(c)(3) | 1999 | $51 million | $21.3 million | 2025-06 |
| Adler University | Education | 501(c)(3) | 1965 | $50.7 million | $49.6 million | 2025-08 |
| Lincoln Park Zoological Society | Animal-related | 501(c)(3) | 1961 | $50.5 million | $254 million | 2025-03 |
| Window To the World Communications Inc | Arts, culture and humanities | 501(c)(3) | 1958 | $50.4 million | $99.7 million | 2025-06 |
| Pilsen Little Village Community Mental Health Center Inc | 501(c)(3) | 1975 | $48.4 million | $42.5 million | 2025-06 | |
| After School Matters Inc | Education | 501(c)(3) | 2001 | $48.4 million | $77.8 million | 2025-06 |
| Easter Seals Inc | 501(c)(3) | 1944 | $47.5 million | $43.9 million | 2025-12 | |
| Lawyers Trust Fund of Illinois | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1983 | $47.4 million | $83.3 million | 2025-06 |
| United Way of Metropolitan Chicago Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2004 | $47.1 million | $48.8 million | 2025-06 |
| Paws Chicago | Animal-related | 501(c)(3) | 1999 | $47 million | $150.1 million | 2024-12 |
| Polish National Alliance of the United States of North America | 501(c)(8) | 1940 | $45.6 million | $449.1 million | 2024-12 | |
| Resurrection Project | Housing and shelter | 501(c)(3) | 1988 | $45.5 million | $54.2 million | 2024-12 |
| Illinois College of Optometry | Education | 501(c)(3) | 1956 | $45.4 million | $105.6 million | 2025-06 |
| Alliance for Clinical Trials in Oncology Foundation | Medical research | 501(c)(3) | 1994 | $44.5 million | $112.8 million | 2024-12 |
| Service Employees International Union | 501(c)(5) | 1943 | $44.3 million | $40.7 million | 2024-12 | |
| Youth Guidance | Education | 501(c)(3) | 2003 | $44.3 million | $45.6 million | 2025-06 |
| University of Chicago Self Insurance Trust | Mutual and membership benefit | 501(c)(3) | $44.2 million | $268.6 million | 2025-06 | |
| Chicago Convention & Tourism Bureau Inc | 501(c)(6) | 1971 | $44.1 million | $33.3 million | 2024-12 | |
| Consumers Power Company Union Welfare Trust To Provide for Retiree | 501(c)(9) | 1995 | $44.1 million | $946.9 million | 2025-12 | |
| Center for Housing and Health | Housing and shelter | 501(c)(3) | 2010 | $43.1 million | $8.3 million | 2025-06 |
| Jewish Child and Family Services | Human services | 501(c)(3) | 1944 | $42.4 million | $95.1 million | 2025-06 |
| Global Charitable Fund | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2017 | $42.4 million | $6.4 million | 2025-12 |
| Tapestry 360 Health | 501(c)(3) | 1993 | $42.2 million | $17.9 million | 2025-06 | |
| Intrinsic Schools | Education | 501(c)(3) | 2013 | $42.2 million | $95.9 million | 2025-06 |
| Society of Thoracic Surgeons | 501(c)(6) | 1979 | $42.1 million | $100.8 million | 2024-12 | |
| Chicago Federation Teachers Union | 501(c)(5) | 1967 | $42 million | $28.4 million | 2025-06 | |
| United Food & Commercial Workers Union Local 1546 Health & Welfare | 501(c)(9) | 1951 | $41.9 million | $70 million | 2025-08 | |
| Delta Dental Plans Association | 501(c)(6) | 1997 | $41.5 million | $28.2 million | 2024-12 | |
| Aids Foundation of Chicago | Diseases, disorders and medical disciplines | 501(c)(3) | 1986 | $41 million | $21.7 million | 2025-06 |
| Carole Robertson Center for Learning | Human services | 501(c)(3) | 1976 | $40.7 million | $27.4 million | 2025-06 |
| American Library Association | Education | 501(c)(3) | 1952 | $40.4 million | $97 million | 2025-08 |
| The Joffrey Ballet | Arts, culture and humanities | 501(c)(3) | 1995 | $39.7 million | $64.1 million | 2025-06 |
| International Brotherhood of Teamsters Health & Welfare FD | 501(c)(9) | 1960 | $39.6 million | $109.5 million | 2024-12 | |
| Academy of Nutrition and Dietetics | 501(c)(6) | 1940 | $39.6 million | $66.6 million | 2025-05 | |
| Polish Roman Catholic Union of America | 501(c)(8) | 1940 | $39.5 million | $225.5 million | 2024-12 | |
| Childrens Hospital of Chicago Medical Center | Health care | 501(c)(3) | 1987 | $39.2 million | $363,694 | 2025-08 |
| South Side Healthy Community Organization Inc | Health care | 501(c)(3) | 2022 | $38.1 million | $33.3 million | 2024-12 |
| YWCA Metropolitan Chicago | Human services | 501(c)(3) | 1934 | $37.9 million | $32.1 million | 2025-06 |
| Primecare Community Health Inc | 501(c)(3) | 1992 | $37.8 million | $53.8 million | 2024-12 | |
| University Club of Chicago | 501(c)(7) | 1941 | $37.6 million | $48.9 million | 2025-09 | |
| Perspectives Charter School | Education | 501(c)(3) | 1997 | $37.6 million | $60.6 million | 2025-06 |
| Interfaith America | Religion-related | 501(c)(3) | 2004 | $36.9 million | $47 million | 2025-07 |
| Building Material Chauffeurs TMSTRS & Helpers Welfare Fund of Chicago | 501(c)(9) | 1951 | $36.7 million | $64.6 million | 2025-08 | |
| Service Employees International Union Local 1 | 501(c)(5) | 1943 | $36.6 million | $18.8 million | 2024-12 | |
| Exelon Corporation Employees Benefit Trust for Union Employees | 501(c)(9) | 1996 | $36.4 million | $709.2 million | 2024-12 | |
| Secure Community Network Inc | Public safety, disaster preparedness and relief | 501(c)(3) | 2006 | $36.4 million | $15.4 million | 2025-12 |
| McDermott Center | 501(c)(3) | 1976 | $36.2 million | $60.6 million | 2025-06 | |
| Aisc Holdings Inc | 501(c)(6) | 1998 | $36.1 million | $50.9 million | 2025-12 | |
| American Osteopathic Association | Diseases, disorders and medical disciplines | 501(c)(3) | 1959 | $35.8 million | $109.1 million | 2025-05 |
| Chicago Public Media Inc | Arts, culture and humanities | 501(c)(3) | 1994 | $35.6 million | $123.1 million | 2025-06 |
| Chicago School of Professional Psychology Inc | Education | 501(c)(3) | 1980 | $35.5 million | $82 million | 2025-05 |
| Assyrian National Council of Illinois | Human services | 501(c)(3) | 1987 | $34.8 million | $21.5 million | 2025-12 |
| Association for Supply Chain Management Inc | 501(c)(6) | 1964 | $34.6 million | $36.3 million | 2024-12 | |
| Pepco Holdings Inc Veba Trust | Mutual and membership benefit | 501(c)(9) | 1999 | $34.4 million | $331.7 million | 2024-12 |
| New Life Centers of Chicagoland NFP | Youth development | 501(c)(3) | 2005 | $34.4 million | $11.6 million | 2024-12 |
| National Board of Osteopathic Medical Examiners Inc | Arts, culture and humanities | 501(c)(3) | 1997 | $34.1 million | $49.8 million | 2024-12 |
| Erikson Institute | Education | 501(c)(3) | 1966 | $33.4 million | $104.7 million | 2025-06 |
| Safer Foundation | Crime and legal-related | 501(c)(3) | 1972 | $33.4 million | $26.7 million | 2025-06 |
| Union League Club of Chicago | 501(c)(7) | 1922 | $33.2 million | $30.2 million | 2025-04 | |
| Chicago Community Loan Fund | Community improvement and capacity building | 501(c)(3) | 1991 | $32.7 million | $216 million | 2025-12 |
| American Health Information Management Association | 501(c)(6) | 1945 | $32.6 million | $65.5 million | 2024-12 | |
| Family Focus | Human services | 501(c)(3) | 1951 | $32.5 million | $49.9 million | 2025-06 |
| International Brotherhood of Electrical Workers | 501(c)(5) | 1940 | $32.4 million | $84.7 million | 2025-12 | |
| Lawrence Hall | 501(c)(3) | 1943 | $32 million | $50.5 million | 2025-06 | |
| Chicago Theatre Group Inc | Arts, culture and humanities | 501(c)(3) | 1977 | $32 million | $68 million | 2025-08 |
| Treatment Alternatives for Stronger Communities | Mental health and crisis intervention | 501(c)(3) | 1979 | $31.8 million | $31.6 million | 2025-06 |
| Uchicago Medicine Northwest Indiana Inc | Health care | 501(c)(3) | 2024 | $31.8 million | $81.8 million | 2025-06 |
| United Airlines Technicians and Related Employees HRA&RHA Plans | Mutual and membership benefit | 501(c)(9) | 2018 | $31.8 million | $51.4 million | 2024-12 |
| Catalyst Schools | Education | 501(c)(3) | 2007 | $31.7 million | $21.3 million | 2025-06 |
| Chicago Sun-Times Media Inc | 501(c)(3) | 2022 | $31.4 million | $24.4 million | 2025-06 | |
| Midway Airlines Terminal Consortium | Community improvement and capacity building | 501(c)(6) | 1999 | $30.6 million | $3.6 million | 2024-12 |
| El Valor Corporation | 501(c)(3) | 1975 | $30.6 million | $22.5 million | 2025-06 | |
| American Bar Endowment | Crime and legal-related | 501(c)(3) | 1944 | $30.4 million | $224 million | 2025-06 |
| Search360 | 501(c)(3) | 1970 | $30.4 million | $33.2 million | 2025-06 | |
| Admiral at the Lake | Human services | 501(c)(3) | 1935 | $30.3 million | $136.4 million | 2025-12 |
| Legal Aid Chicago | Crime and legal-related | 501(c)(3) | 1973 | $30.3 million | $21 million | 2025-12 |
| Wellness West Inc | 501(c)(3) | 2022 | $29.8 million | $17.2 million | 2024-12 | |
| Alivio Medical Center Inc | Health care | 501(c)(3) | 1989 | $29.7 million | $26 million | 2025-06 |
| American Society of Clinical Pathologists | 501(c)(3) | 1943 | $29.3 million | $48.8 million | 2025-06 | |
| University of Western States | Diseases, disorders and medical disciplines | 501(c)(3) | 1950 | $29.1 million | $83.2 million | 2025-05 |
| Center for Technology and Civic Life | Public and societal benefit | 501(c)(3) | 2015 | $29 million | $86.5 million | 2025-01 |
| Exelon Corp Employees Benefit Trust for Management Employees | 501(c)(9) | 1996 | $29 million | $104.6 million | 2024-12 | |
| Kansas Health Science University Inc | Education | 501(c)(3) | 2018 | $28.8 million | $92 million | 2025-05 |
| Onegoal | Youth development | 501(c)(3) | 2003 | $28.8 million | $54 million | 2025-06 |
| Southwest Organizing Project | Community improvement and capacity building | 501(c)(3) | 1996 | $28.7 million | $25.4 million | 2025-06 |
| Pacific Oaks Education Corporation | Education | 501(c)(3) | 1959 | $28.4 million | $53.3 million | 2025-05 |
| Coca-Cola Co Postretireme Medical Voluntary Emp Beneficiary | Mutual and membership benefit | 501(c)(9) | 2009 | $28.4 million | $40,943 | 2024-12 |
| Institute of Food Techologists Inc | 501(c)(3) | 1952 | $28.3 million | $59.4 million | 2025-08 | |
| Braven Incorporated | Youth development | 501(c)(3) | 2014 | $28.2 million | $49.8 million | 2025-06 |
| Near North Health Service Corporation | Health care | 501(c)(3) | 1983 | $28.1 million | $40.1 million | 2025-06 |
| Heartland Alliance Health | Health care | 501(c)(3) | 1992 | $28.1 million | $12.3 million | 2024-06 |
| Steppenwolf Theater Co | Arts, culture and humanities | 501(c)(3) | 1976 | $28 million | $119.1 million | 2025-08 |
| Trust Evergreen Park Corp | Community improvement and capacity building | 501(c)(25) | 2008 | $27.3 million | $871,827 | 2025-06 |
| Association for Corporate Growth Inc | 501(c)(6) | 1984 | $27.3 million | $14.5 million | 2024-08 | |
| Saybrook University | 501(c)(3) | 1972 | $27.3 million | $25.4 million | 2025-05 | |
| Chapin Hall Center for Children | Human services | 501(c)(3) | 1934 | $27 million | $57.6 million | 2025-06 |
| Washington and Jane Smith Community Beverly | Human services | 501(c)(3) | 1934 | $26.7 million | $72.4 million | 2025-06 |
| Lydia Home Association | Human services | 501(c)(3) | 1942 | $26.7 million | $18.3 million | 2025-06 |
| Chicago House and Social Service Agency | Diseases, disorders and medical disciplines | 501(c)(3) | 1986 | $26.4 million | $19.3 million | 2025-06 |
| Christian Community Health Center | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1992 | $26.3 million | $42.6 million | 2025-06 |
| Ui Labs | Education | 501(c)(3) | 2014 | $26 million | $31 million | 2024-12 |
| Service Employees International Union 4B Health & Welfare Fund | 501(c)(9) | 1961 | $25.6 million | $18.9 million | 2025-06 | |
| Chicago Low Income Housing Trust Fund | Housing and shelter | 501(c)(3) | 1990 | $25.5 million | $75.5 million | 2024-12 |
| Catholic Health Foundation of Northern Illinois | 501(c)(3) | 1946 | $25.2 million | $25.2 million | 2025-06 | |
| American Board of Medical Specialties | 501(c)(6) | 1964 | $25.2 million | $46.2 million | 2025-12 | |
| Museum of Contemporary Art | Arts, culture and humanities | 501(c)(3) | 1966 | $25 million | $213.3 million | 2025-06 |
| University of Chicago Charter School Corporation | Education | 501(c)(3) | 1999 | $24.9 million | $21.5 million | 2025-06 |
| Community Investment Corp | Housing and shelter | 501(c)(3) | 1974 | $24.8 million | $374.7 million | 2025-09 |
| United Association of Journeymen & Apprentices of the Plumbing & Pipe | 501(c)(5) | 1941 | $24.8 million | $31 million | 2025-06 | |
| Kleo Community Family Life Center | Education | 501(c)(3) | 2008 | $24.7 million | $639,113 | 2025-12 |
| Government Finance Officers Association of the United States & Canada | Public and societal benefit | 501(c)(3) | 1942 | $24.7 million | $22.3 million | 2025-03 |
| Center for Better Aging | Health care | 501(c)(3) | 2024 | $24.7 million | $18 million | 2024-12 |
| Chinese American Service League Inc | Community improvement and capacity building | 501(c)(3) | 1979 | $24.7 million | $21 million | 2025-06 |
| Lycee Francais de Chicago Inc | Education | 501(c)(3) | 1995 | $24.5 million | $53.3 million | 2025-06 |
| B U I L D Incorporated | 501(c)(3) | 1969 | $24.3 million | $28.5 million | 2025-06 | |
| Full Circle Communities Inc | Housing and shelter | 501(c)(3) | 2001 | $24.2 million | $408.8 million | 2024-12 |
| North Lawndale Initiative Support Inc | Community improvement and capacity building | 501(c)(3) | 2024 | $24.2 million | $46.8 million | 2024-12 |
| American College of Surgeons Professional Association | Community improvement and capacity building | 501(c)(6) | 2002 | $24.1 million | $12.2 million | 2025-06 |
| Auditorium Theatre of Roosevelt University Inc | Arts, culture and humanities | 501(c)(3) | 1982 | $24 million | $18.4 million | 2025-08 |
| Sga Youth & Family Services NFP | Human services | 501(c)(3) | 1952 | $23.9 million | $24.9 million | 2025-06 |
| Rincon Family Services | Mental health and crisis intervention | 501(c)(3) | 1978 | $23.6 million | $15.6 million | 2025-06 |
| Institute for Latino Progress | Human services | 501(c)(3) | 1977 | $23.4 million | $25.1 million | 2025-06 |
| A Safe Haven Foundation | Mental health and crisis intervention | 501(c)(3) | 2003 | $23.4 million | $45.8 million | 2025-06 |
| Human Resources Development Institute Inc | Human services | 501(c)(3) | 1978 | $23.2 million | $20.5 million | 2025-06 |
| Casa Central Social Services Corporation | Human services | 501(c)(3) | 1972 | $22.9 million | $9.1 million | 2025-06 |
| United Association of Journeymen & Apprentices of the Plumbing & Pipe | 501(c)(5) | 1941 | $22.9 million | $41 million | 2024-12 | |
| XS Tennis and Education Foundation | Recreation and sports | 501(c)(3) | 2009 | $22.7 million | $21.7 million | 2024-12 |
| Childrens Memorial Hospital Self | Mutual and membership benefit | 501(c)(3) | 1977 | $22.4 million | $200.9 million | 2025-08 |
| Leading Educators Inc | Education | 501(c)(3) | 2011 | $22.4 million | $33.5 million | 2025-06 |
| Alternative Schools Network | 501(c)(3) | 1974 | $22.3 million | $5.7 million | 2025-06 | |
| University of Missouri Medical Professional Liability Trust | Mutual and membership benefit | 501(c)(3) | 1978 | $22.3 million | $70.2 million | 2025-06 |
| Association House of Chicago | Human services | 501(c)(3) | 1961 | $22.3 million | $26.5 million | 2025-06 |
| JFMC Facilities Corporation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1985 | $22.2 million | $123.6 million | 2025-06 |
| Nijc NFP | Crime and legal-related | 501(c)(3) | 2024 | $22.1 million | $17.5 million | 2025-06 |
| Adler Planetarium | Arts, culture and humanities | 501(c)(3) | 1968 | $22 million | $72.6 million | 2025-06 |
| Glenkirk | Human services | 501(c)(3) | 1954 | $21.7 million | $25.3 million | 2025-06 |
| Kids Above All Illinois | 501(c)(3) | 1934 | $21.5 million | $8.2 million | 2025-06 | |
| Commercial Club Foundation | 501(c)(3) | 1986 | $21.5 million | $44.4 million | 2025-06 | |
| Michael Reese Health Trust | Health care | 501(c)(3) | 2024 | $21.5 million | $162.9 million | 2025-06 |
| Norwood Crossing Association | Human services | 501(c)(3) | 1937 | $21.4 million | $26.5 million | 2024-12 |
| Hope International Development Agency | International, foreign affairs and national security | 501(c)(3) | 1997 | $21.4 million | $205,237 | 2024-12 |
| Girl Scouts of Greater Chicago & Northwest Indiana | Youth development | 501(c)(3) | 1993 | $21.3 million | $45.1 million | 2025-09 |
| Pritzker Family Philanthropic Fund | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1990 | $21.1 million | $201.7 million | 2024-12 |
| Action for Healthy Kids Inc | Education | 501(c)(3) | 2003 | $21 million | $3 million | 2025-06 |
| Northwestern University Settlement | Human services | 501(c)(3) | 1947 | $21 million | $31.1 million | 2025-06 |
| The Young Center for Immigrant Childrens Rights | Human services | 501(c)(3) | 2014 | $21 million | $17 million | 2025-09 |
| Rapid Resist Action | Civil rights, social action and advocacy | 501(c)(4) | 2021 | $20.9 million | $13.6 million | 2025-09 |
| Cara Program | Employment | 501(c)(3) | 1999 | $20.9 million | $26.5 million | 2025-06 |
| National Board of Certification and Recert of Nurse Anesthetists | Community improvement and capacity building | 501(c)(6) | 2009 | $20.8 million | $48.2 million | 2024-12 |
| Christopher House | Human services | 501(c)(3) | 1970 | $20.7 million | $27.6 million | 2025-06 |
| Peco Energy Company Retiree Medical Trust | 501(c)(9) | 1996 | $20.7 million | $149.5 million | 2024-12 | |
| Friends of the Orphans | International, foreign affairs and national security | 501(c)(3) | 2004 | $20.7 million | $18 million | 2025-06 |
| Aspira Inc of Illinois | 501(c)(3) | 1969 | $20.5 million | $28.9 million | 2025-06 | |
| Professional Convention Management Association | 501(c)(6) | 1967 | $20.3 million | $17.6 million | 2024-12 | |
| Henry Booth House | Human services | 501(c)(3) | 1988 | $20.2 million | $3 million | 2025-06 |
| National Able Network Inc | 501(c)(3) | 1974 | $20.1 million | $14.6 million | 2025-06 | |
| Healthcare Alternative Systems Inc | Mental health and crisis intervention | 501(c)(3) | 1975 | $20.1 million | $26.6 million | 2025-06 |
| Montgomery Place | 501(c)(3) | 1988 | $20 million | $26.8 million | 2025-06 | |
| European American Association | Housing and shelter | 501(c)(3) | 1992 | $19.9 million | $29.3 million | 2025-12 |
| American Planning Association | Community improvement and capacity building | 501(c)(3) | 1983 | $19.9 million | $35 million | 2025-09 |
| Foundation of the American College of Healthcare Executives | Education | 501(c)(3) | 1944 | $19.8 million | $97.3 million | 2024-12 |
| Cleveland Avenue Foundation for Education Group | Education | 501(c)(3) | 2021 | $19.6 million | $28.7 million | 2024-12 |
| Nourishing Hope | 501(c)(3) | 1972 | $19.6 million | $10.8 million | 2025-03 | |
| Mhub Support Corporation | Community improvement and capacity building | 501(c)(3) | 2023 | $19.3 million | $68.7 million | 2024-12 |
| Breakthrough Urban Ministries Inc | 501(c)(3) | 1992 | $19.1 million | $17.6 million | 2025-06 | |
| Albert and Lucille Delighter and Marcella Winston Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2006 | $19.1 million | $141.4 million | 2025-06 |
| Hektoen Institute for Medical Research | Health care | 501(c)(3) | 1945 | $18.9 million | $80.1 million | 2025-08 |
| Laborers International Union of North America | Employment | 501(c)(5) | 1968 | $18.9 million | $48.5 million | 2025-05 |
| Leslie Shankman School Corporation | Education | 501(c)(3) | 1995 | $18.8 million | $23.7 million | 2025-06 |
| North American Association of Food Equipment Manufacturers | 501(c)(6) | 1965 | $18.8 million | $30.7 million | 2025-12 | |
| First Northern Credit Union | 501(c)(14) | 1945 | $18.8 million | $327.1 million | 2025-12 | |
| Motion Picture Studio Mechanics Union Local 476 Welfare Fund | 501(c)(9) | 1974 | $18.7 million | $19.9 million | 2025-12 | |
| Bernard Zell Anshe Emet Day School | Education | 501(c)(3) | 1957 | $18.7 million | $42 million | 2025-06 |
| Hope Chicago Inc | 501(c)(3) | 2021 | $18.7 million | $27.2 million | 2025-06 | |
| Inner-City Muslim Action Network | Community improvement and capacity building | 501(c)(3) | 1999 | $18.5 million | $18.3 million | 2024-12 |
| Lester and Rosalie Anixter Center | Housing and shelter | 501(c)(3) | 2008 | $18.5 million | $10.7 million | 2025-06 |
| LCN Title Holding Corporation NFP | Community improvement and capacity building | 501(c)(2) | 2020 | $18.5 million | $16.2 million | 2024-12 |
| Ibew Local 134-Neca Vacation Savings Trust Fund | Mutual and membership benefit | 501(c)(9) | 2018 | $18.4 million | $3.7 million | 2025-06 |
| Appraisal Institute | 501(c)(6) | 1992 | $18.2 million | $34.4 million | 2024-12 | |
| Institute for Responsive Government Inc | Public and societal benefit | 501(c)(3) | 2024 | $18 million | $6.4 million | 2024-12 |
| Volunteers of America Inc | 501(c)(3) | 1965 | $17.7 million | $18.4 million | 2025-06 | |
| Food Export Association of the Midwest USA | 501(c)(5) | 1993 | $17.7 million | $3.7 million | 2024-12 | |
| Marillac St Vincent Family Services Inc | Human services | 501(c)(3) | 1946 | $17.7 million | $17.9 million | 2025-06 |
| Trust Agreement of the Retiree Medical Plan of the Plumbers | Mutual and membership benefit | 501(c)(9) | 2015 | $17.6 million | $61.9 million | 2025-05 |
| Iit Research Institute | Science and technology | 501(c)(3) | 1941 | $17.5 million | $36.3 million | 2025-09 |
| Higher Learning Commission | Education | 501(c)(3) | 2001 | $17.5 million | $34.7 million | 2025-08 |
| Johnson and Johnson Health Benefits Trust for Union Employees | 501(c)(9) | 1989 | $17.3 million | $918,402 | 2025-12 | |
| Chicago Shakespeare Theater | Arts, culture and humanities | 501(c)(3) | 1987 | $17.2 million | $56.8 million | 2025-06 |
| Greenheart International | International, foreign affairs and national security | 501(c)(3) | 1986 | $17.2 million | $6.2 million | 2025-08 |
| Golden Apple Foundation for Excellence in Teaching | 501(c)(3) | 1985 | $17.2 million | $9.9 million | 2024-12 | |
| Catherine Cook School | 501(c)(3) | 1976 | $17.2 million | $35.6 million | 2025-06 | |
| Prestressed Concrete Institute | 501(c)(6) | 1962 | $17.1 million | $13.1 million | 2025-06 | |
| Local 734 Welfare Fund | 501(c)(9) | 1958 | $17.1 million | $14.4 million | 2025-12 | |
| Pillars Fund | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2016 | $17 million | $20.9 million | 2025-12 |
| Loyola Press | 501(c)(3) | 1946 | $17 million | $33.9 million | 2025-09 | |
| International Brotherhood of Teamsters | 501(c)(5) | 1969 | $17 million | $42.3 million | 2024-12 | |
| Near North Montessori School | Education | 501(c)(3) | 1965 | $17 million | $36.9 million | 2025-07 |
| Association of Diabetes Care & Education Specialists | 501(c)(6) | 1985 | $16.9 million | $22.1 million | 2024-12 | |
| American Marketing Association Inc | Community improvement and capacity building | 501(c)(3) | 1992 | $16.8 million | $11.8 million | 2025-06 |
| Community Health NFP | Health care | 501(c)(3) | 1992 | $16.8 million | $6.9 million | 2024-12 |
| By the Hand Club for Kids | 501(c)(3) | 2005 | $16.8 million | $45.9 million | 2025-08 | |
| Boys & Girls Clubs of Chicago Inc | Youth development | 501(c)(3) | 1923 | $16.8 million | $61.9 million | 2025-06 |
| Service Employees International Union | 501(c)(5) | 1943 | $16.7 million | $7.6 million | 2024-12 | |
| Gads Hill Center | Human services | 501(c)(3) | 1926 | $16.7 million | $11.8 million | 2025-06 |
| One Family Illinois | Human services | 501(c)(3) | 1991 | $16.5 million | $49.3 million | 2024-12 |
| Asian Human Services of Chicago Inc | Human services | 501(c)(3) | 1979 | $16.5 million | $7.9 million | 2025-06 |
| Asian Human Services Family Health Center Inc | Health care | 501(c)(3) | 2002 | $16.4 million | $31 million | 2025-06 |
| GW Foundation Inc | Mental health and crisis intervention | 501(c)(3) | 1985 | $16.3 million | $131.7 million | 2025-06 |
| Chicago Abortion Fund | 501(c)(3) | 1986 | $16.2 million | $10 million | 2025-06 | |
| Forefront | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1974 | $16.1 million | $18.5 million | 2025-06 |
| Illinois Public Health Institute | Health care | 501(c)(3) | 2009 | $16 million | $6.8 million | 2025-12 |
| Old Town School of Folk Music Inc | Arts, culture and humanities | 501(c)(3) | 1962 | $16 million | $27.6 million | 2025-12 |
| Institute for Nonviolence Chicago | Crime and legal-related | 501(c)(3) | 2016 | $15.9 million | $4.4 million | 2025-06 |
| Urhai Community Service Center | Human services | 501(c)(3) | 2001 | $15.9 million | $22.9 million | 2025-12 |
| The Center for Economic Research and Social Change Inc | Arts, culture and humanities | 501(c)(3) | 2022 | $15.8 million | $24.6 million | 2025-08 |
| Financial Health Network Inc | Community improvement and capacity building | 501(c)(3) | 2006 | $15.7 million | $22.8 million | 2024-12 |
| Chicago Jewish Day School | Education | 501(c)(3) | 2001 | $15.6 million | $29.3 million | 2025-06 |
| Illinois Equal Justice Foundation | 501(c)(3) | 1986 | $15.5 million | $11.3 million | 2025-06 | |
| United Methodist Homes and Services | Human services | 501(c)(3) | 1991 | $15.5 million | $4.1 million | 2024-12 |
| Chicago Bar Foundation | Education | 501(c)(3) | 1949 | $15.4 million | $10.1 million | 2025-05 |
| Academy of General Dentistry | 501(c)(6) | 1972 | $15.4 million | $48.4 million | 2025-12 | |
| Anti-Cruelty Society | Animal-related | 501(c)(3) | 1937 | $15.4 million | $59.3 million | 2025-10 |
| Hispanic Housing Development Corp | 501(c)(3) | 1977 | $15.4 million | $76.4 million | 2024-12 | |
| Chicago Truck Drivers HLPRS & Whse | Mutual and membership benefit | 501(c)(9) | 1957 | $15.3 million | $35.8 million | 2025-03 |
| Erie Neighborhood House | Human services | 501(c)(3) | 1942 | $15.3 million | $14.4 million | 2025-06 |
| Womens Business Development Center | 501(c)(3) | 1987 | $15.2 million | $8.9 million | 2025-06 | |
| Colorado Park 277 Corporation | 501(c)(25) | 2023 | $15.1 million | $262.9 million | 2024-12 | |
| Childrens First Fund the Chicago Public School Foundation | Education | 501(c)(3) | 1997 | $15.1 million | $27.4 million | 2025-06 |
| International Legal Technology | Community improvement and capacity building | 501(c)(6) | 2014 | $15.1 million | $18.4 million | 2024-12 |
| Heartland Alliance International Inc | Civil rights, social action and advocacy | 501(c)(3) | 2015 | $15 million | $3.3 million | 2025-06 |
| Unite Here | 501(c)(5) | 1998 | $14.9 million | $11 million | 2025-12 | |
| Refugeeone | Religion-related | 501(c)(3) | 1992 | $14.8 million | $16.9 million | 2025-06 |
| Academy for Global Citizenship Charter School | Education | 501(c)(3) | 2006 | $14.8 million | $46.2 million | 2025-06 |
| Chicago Education Partnership | Education | 501(c)(3) | 2014 | $14.8 million | $9.3 million | 2025-06 |
| Association for Corporate Growth Inc | 501(c)(6) | 1984 | $14.8 million | $12.5 million | 2025-08 | |
| Puerto Rican Cultural Center | 501(c)(3) | 1996 | $14.7 million | $14.2 million | 2025-06 | |
| National Society To Prevent Blindness | Diseases, disorders and medical disciplines | 501(c)(3) | 1990 | $14.7 million | $29.2 million | 2025-03 |
| Community Alternatives Unlimited | 501(c)(3) | 1981 | $14.6 million | $7.1 million | 2025-06 | |
| Chinese Mutual Aid Association Inc | Human services | 501(c)(3) | 1981 | $14.6 million | $8.7 million | 2025-06 |
| World Bicycle Relief NFP | Public safety, disaster preparedness and relief | 501(c)(3) | 2006 | $14.5 million | $10.3 million | 2025-12 |
| The Network Advocating Against Domestic Violence | Human services | 501(c)(3) | 1985 | $14.5 million | $4.2 million | 2025-06 |
| Selfhelp Home Inc | Human services | 501(c)(3) | 2000 | $14.5 million | $9.8 million | 2025-09 |
| Institute of Real Estate Management of the Natl Association of Realtors | Community improvement and capacity building | 501(c)(6) | 1976 | $14.4 million | $12.5 million | 2025-12 |
| Chicago Architecture Foundation | Arts, culture and humanities | 501(c)(3) | 1966 | $14.4 million | $26.6 million | 2025-12 |
| Lungevity Foundation | Medical research | 501(c)(3) | 2001 | $14.2 million | $6.2 million | 2025-06 |
| The Ark | Human services | 501(c)(3) | 1972 | $14.2 million | $27.4 million | 2025-06 |
| Wisconsin Energy Corporation Union Retiree Medical Benefits Trust | 501(c)(9) | 1992 | $14.1 million | $241.2 million | 2025-12 | |
| West Side Justice Center Inc | Crime and legal-related | 501(c)(3) | 2016 | $14 million | $6.3 million | 2025-12 |
| Make-A-Wish Foundation of Illinois Inc | 501(c)(3) | 1987 | $14 million | $17.9 million | 2025-08 | |
| Community Educaton Network It Takes A Village Family of Schoo | Education | 501(c)(3) | 2006 | $14 million | $22.6 million | 2025-06 |
| William H Miner Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1950 | $14 million | $128.6 million | 2024-12 |
| Intl Union of Opr Engr 399 | 501(c)(5) | 1941 | $14 million | $24.6 million | 2025-06 | |
| Alliance of Local Service Organizations | Community improvement and capacity building | 501(c)(3) | 1999 | $13.9 million | $9.4 million | 2025-12 |
| Featherfist | Human services | 501(c)(3) | 1993 | $13.9 million | $1.9 million | 2024-12 |
| Merit School of Music | Arts, culture and humanities | 501(c)(3) | 1979 | $13.8 million | $46.9 million | 2025-08 |
| Cristo Rey Network | Education | 501(c)(3) | 2003 | $13.8 million | $31.2 million | 2025-06 |
| Depaul USA Inc | Housing and shelter | 501(c)(3) | 2009 | $13.7 million | $13 million | 2025-12 |
| East-West University Inc | Education | 501(c)(3) | 1980 | $13.7 million | $88.8 million | 2025-08 |
| Covenant Ministries of Benevolence | 501(c)(3) | 1975 | $13.7 million | $66.4 million | 2025-09 | |
| Washington and Jane Smith Home | Housing and shelter | 501(c)(3) | 2000 | $13.6 million | $60.4 million | 2025-06 |
| Jewish Council for Youth Services | Youth development | 501(c)(3) | 1939 | $13.5 million | $17.7 million | 2025-05 |
| American Association of Endodontists | Community improvement and capacity building | 501(c)(6) | 2011 | $13.5 million | $20 million | 2025-06 |
| Acclivus Inc | Health care | 501(c)(3) | 2018 | $13.5 million | $6.5 million | 2023-12 |
| Yeshivas Kesser Yonah | Education | 501(c)(3) | 2006 | $13.4 million | $20.4 million | 2025-08 |
| Child Link Inc | Human services | 501(c)(3) | 2005 | $13.4 million | $5.3 million | 2025-06 |
| Vicinity Credit Union | Public and societal benefit | 501(c)(14) | 2001 | $13.3 million | $275.6 million | 2024-12 |
| American Organization for Nursing Leadership | 501(c)(6) | 1989 | $13.3 million | $26.1 million | 2024-12 | |
| Ccim Institute | Community improvement and capacity building | 501(c)(6) | 1999 | $13.2 million | $22.1 million | 2025-12 |
| Refed Inc | Food, agriculture and nutrition | 501(c)(3) | 2019 | $13.2 million | $15.2 million | 2024-12 |
| Habilitative Systems Incorporated | 501(c)(3) | 1978 | $13.2 million | $9.7 million | 2025-06 | |
| Chicago Youth Centers | Youth development | 501(c)(3) | 1957 | $13.1 million | $18.1 million | 2025-06 |
| Safe Families for Children Alliance | Human services | 501(c)(3) | 2012 | $13.1 million | $8.2 million | 2025-06 |
| North Lawndale College Preparatory Charter High School | Education | 501(c)(3) | 1999 | $13.1 million | $3.5 million | 2025-06 |
| German-American Chamber of Commerce of the Midwest | 501(c)(6) | 1965 | $13.1 million | $11.7 million | 2025-12 | |
| The Global Foodbanking Network | International, foreign affairs and national security | 501(c)(3) | 2006 | $13.1 million | $10.7 million | 2025-06 |
| Romanian American Community Center | Human services | 501(c)(3) | 2022 | $13 million | $9.8 million | 2024-12 |
| National Certification Corporation for Obstetric Gynecologic & Neonat | 501(c)(6) | 1977 | $12.9 million | $46.1 million | 2024-12 | |
| Blue Cross and Blue Shield Plans National Retiree Health Benefits | 501(c)(9) | 1994 | $12.9 million | $207.7 million | 2024-12 | |
| Peoples Action Institute | Community improvement and capacity building | 501(c)(3) | 1973 | $12.8 million | $24.9 million | 2024-12 |
| Asi | 501(c)(3) | 1987 | $12.8 million | $3.3 million | 2025-06 | |
| Aim Art in Motion | Youth development | 501(c)(3) | 2012 | $12.8 million | $41 million | 2025-06 |
| American Society for Surgery of the Hand | Diseases, disorders and medical disciplines | 501(c)(3) | 2013 | $12.7 million | $42.5 million | 2024-12 |
| Chicago Waldorf School | Education | 501(c)(3) | 1966 | $12.7 million | $14.1 million | 2025-06 |
| Defense Research Institute Inc | 501(c)(6) | 1965 | $12.6 million | $17 million | 2024-12 | |
| Ukrainian Catholic Education Foundation | Religion-related | 501(c)(3) | 1997 | $12.5 million | $28 million | 2025-06 |
| Infant Welfare Society of Chicago | 501(c)(3) | 1938 | $12.4 million | $14.5 million | 2025-06 | |
| Thomas More Society | Crime and legal-related | 501(c)(3) | 1999 | $12.4 million | $5.6 million | 2025-12 |
| Intl Un of Operating Engrs Local 399 Health Reimbursement Account | Mutual and membership benefit | 501(c)(9) | 2014 | $12.4 million | $61.4 million | 2025-05 |
| Chicago Childrens Advocacy Center | Crime and legal-related | 501(c)(3) | 1999 | $12.4 million | $10.1 million | 2025-06 |
| Tca Health Inc NFP | Health care | 501(c)(3) | 1973 | $12.3 million | $17.4 million | 2025-06 |
| Alliancechicago | Health care | 501(c)(3) | 2017 | $12.3 million | $12.4 million | 2025-06 |
| Brighton Park Neighborhood Council | Community improvement and capacity building | 501(c)(3) | 1998 | $12.3 million | $7 million | 2024-12 |
| National Assoc for Health Care Quality | Health care | 501(c)(6) | $12.2 million | $10 million | 2024-12 | |
| Betty Shabazz International Charter School | Education | 501(c)(3) | 1999 | $12.2 million | $13.3 million | 2025-06 |
| Westside Health Authority | Housing and shelter | 501(c)(3) | 1996 | $12.2 million | $26.9 million | 2025-06 |
| Responsive Gov Action Inc | Civil rights, social action and advocacy | 501(c)(4) | 2024 | $12.1 million | $3.5 million | 2024-12 |
| Youth Outreach Services Inc | Human services | 501(c)(3) | 1984 | $12.1 million | $4.1 million | 2025-06 |
| Environmental Law & Policy Center of the Midwest | Environment | 501(c)(3) | 1993 | $12.1 million | $45.6 million | 2025-06 |
| National Center for Teacher Residencies Inc | Education | 501(c)(3) | 2008 | $12 million | $13.2 million | 2025-06 |
| Blue Cross Blue Shield Assoc Retire Benefit Trust | 501(c)(9) | 1996 | $12 million | $98.4 million | 2024-12 | |
| Muslim Community Center Incorporate | Religion-related | 501(c)(3) | 1970 | $12 million | $23.9 million | 2025-06 |
| Chicago Historical Society | Arts, culture and humanities | 501(c)(3) | 1932 | $11.9 million | $126.6 million | 2025-06 |
| American Epilepsy Society | Diseases, disorders and medical disciplines | 501(c)(3) | 1975 | $11.9 million | $22 million | 2025-06 |
| Ridgemoor Country Club | 501(c)(7) | 1942 | $11.8 million | $19.5 million | 2025-03 | |
| Housing Opportunities for Women Inc | Housing and shelter | 501(c)(3) | 1984 | $11.8 million | $9.4 million | 2025-12 |
| Chicago High School for the Arts | Education | 501(c)(3) | 2009 | $11.7 million | $1.3 million | 2025-06 |
| Kaleidoscope Inc | 501(c)(3) | 1977 | $11.6 million | $7.1 million | 2025-06 | |
| Great Lakes Academy Inc | Education | 501(c)(3) | 2014 | $11.6 million | $13.9 million | 2025-06 |
| American Academy of Pediatric Dentistry | Community improvement and capacity building | 501(c)(6) | 2012 | $11.6 million | $14.7 million | 2025-06 |
| Chicago Mathematics and Science Academy Charter School Inc | Education | 501(c)(3) | 2003 | $11.6 million | $21.1 million | 2025-06 |
| Project Vida Inc | Human services | 501(c)(3) | 2023 | $11.6 million | $2.2 million | 2024-12 |
| Society of Gynecologic Oncology | Health care | 501(c)(6) | 2014 | $11.5 million | $10.2 million | 2025-12 |
| Openlands | 501(c)(3) | 1968 | $11.5 million | $43.3 million | 2025-09 | |
| The Academy Group | Education | 501(c)(3) | 2019 | $11.5 million | $612,585 | 2025-06 |
| Urban Sustainability Directors Network | Environment | 501(c)(3) | 2019 | $11.3 million | $16.7 million | 2024-12 |
| Access Living of Metropolitan Chicago | 501(c)(3) | 1984 | $11.3 million | $40.8 million | 2025-06 | |
| American Academy of Periodontology | 501(c)(6) | 1988 | $11.3 million | $25.3 million | 2024-12 | |
| Dental Assisting National Board Incorporated | 501(c)(6) | 1949 | $11.3 million | $13.3 million | 2025-12 | |
| Chicago Dental Society | Community improvement and capacity building | 501(c)(6) | 1935 | $11.3 million | $39.8 million | 2024-12 |
| Alzheimers Impact Movement | Diseases, disorders and medical disciplines | 501(c)(4) | 2010 | $11.3 million | $859,243 | 2025-06 |
| Nami Chicago | 501(c)(3) | 1980 | $11.2 million | $10.8 million | 2025-06 | |
| Renaissance Social Services Inc | Human services | 501(c)(3) | 1994 | $11.2 million | $3.4 million | 2024-12 |
| Lake View Towers Residents Association Inc | Housing and shelter | 501(c)(3) | 1995 | $11.1 million | $42.5 million | 2025-12 |
| Enlace Chicago | Community improvement and capacity building | 501(c)(3) | 1999 | $11.1 million | $10.5 million | 2025-06 |
| Mercy Circle | 501(c)(3) | 1946 | $11.1 million | $32.2 million | 2025-06 | |
| Federal Defender Program Inc | 501(c)(3) | 1965 | $11.1 million | $853,747 | 2025-09 | |
| Center for Specialized Realtor Education Inc | 501(c)(6) | 1998 | $11.1 million | $25.3 million | 2024-12 | |
| Chicago Metropolitan Housing Development Corporation | Housing and shelter | 501(c)(3) | 1997 | $11 million | $49.5 million | 2025-12 |
| Accreditation Council for Continuing Medical Education | Education | 501(c)(3) | 2004 | $11 million | $24.2 million | 2025-12 |
| Chicago Club | 501(c)(7) | 1934 | $11 million | $22.5 million | 2024-12 | |
| Reclaiming Chicago NFP | Housing and shelter | 501(c)(3) | 2021 | $11 million | $41.9 million | 2025-12 |
| Alliance NCTN Foundation | Diseases, disorders and medical disciplines | 501(c)(3) | 2020 | $10.9 million | $4.5 million | 2024-12 |
| Toyota Technological Institute at Chicago | Education | 501(c)(3) | 2004 | $10.7 million | $307.3 million | 2025-06 |
| Fraternal Order of Police | 501(c)(8) | 1952 | $10.7 million | $19 million | 2024-12 | |
| Saddle and Cycle Club | 501(c)(7) | 1944 | $10.7 million | $18 million | 2024-12 | |
| Garden Center Services | 501(c)(3) | 1958 | $10.6 million | $9.9 million | 2025-06 | |
| The Night Ministry | Human services | 501(c)(3) | 1984 | $10.6 million | $17.7 million | 2025-06 |
| Walden Oaks Apartments Preservation NFP | Housing and shelter | 501(c)(3) | 2005 | $10.6 million | $8.7 million | 2024-12 |
| La Casa Norte | Housing and shelter | 501(c)(3) | 1997 | $10.6 million | $21.6 million | 2024-12 |
| Pert Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2003 | $10.5 million | $127.6 million | 2025-09 |
| American College of Foot and Ankle Surgeons | Education | 501(c)(3) | 2013 | $10.4 million | $19.8 million | 2024-12 |
| Workers United | 501(c)(5) | 2010 | $10.4 million | $10 million | 2025-12 | |
| Housing and Human Development Corporation | Housing and shelter | 501(c)(3) | 2017 | $10.4 million | $70 million | 2024-12 |
| Primo Center for Women and Children | Education | 501(c)(3) | 1978 | $10.4 million | $9.7 million | 2025-06 |
| Chicago Urban League | Employment | 501(c)(3) | 1948 | $10.3 million | $11.8 million | 2025-06 |
| Womans Athletic Club of Chicago | 501(c)(7) | 1944 | $10.3 million | $19.3 million | 2025-03 | |
| Mary Crane League | 501(c)(3) | 1942 | $10.2 million | $5.2 million | 2025-06 | |
| International Council for Veterinary Assessment | Diseases, disorders and medical disciplines | 501(c)(3) | 1996 | $10.2 million | $18.9 million | 2025-05 |
| International Society of Transport Aircraft Traders | 501(c)(6) | 1993 | $10.1 million | $17.3 million | 2024-12 | |
| Concordia Place | Human services | 501(c)(3) | 2003 | $10.1 million | $8.9 million | 2025-06 |
| Grant Park Orchestral Association | Arts, culture and humanities | 501(c)(3) | 2002 | $10.1 million | $37.3 million | 2025-12 |
| Maestro Cares Foundation | International, foreign affairs and national security | 501(c)(3) | 2012 | $10.1 million | $16.3 million | 2024-12 |
By cause in Chicago, IL
- Religion-related 1,986
- Education 1,843
- Philanthropy, voluntarism and grantmaking foundations 1,565
- Arts, culture and humanities 1,527
- Human services 1,518
- Community improvement and capacity building 961
- Youth development 545
- Recreation and sports 464
- Health care 395
- Housing and shelter 319
- Mental health and crisis intervention 273
- Crime and legal-related 217
- Employment 216
- Public and societal benefit 185
- International, foreign affairs and national security 172
- Civil rights, social action and advocacy 167
- Food, agriculture and nutrition 147
- Environment 146
- Diseases, disorders and medical disciplines 133
- Animal-related 121
- Mutual and membership benefit 103
- Medical research 85
- Science and technology 72
- Public safety, disaster preparedness and relief 41
- Social science 34
Nonprofits in every city of the state
Read from the IRS Exempt Organizations Business Master File, updated by the IRS on October 24, 2026 and rebuilt here every morning. Revenue and assets are from each organization's latest filing as the IRS lists it; the IRS record is the official one. Organizations only: no people are named on these pages.