Data / Federal grants / PAR-27-137
Undiagnosed Diseases Network (UDN) Clinical Networks of Diagnostic Excellence
National Institutes of Health (Department of Health and Human Services) expects to post this opportunity around March 25, 2027, with applications due around May 25, 2027.
SpecStream is the live web data engine for teams and agents. It reads every open and forecast federal opportunity on Grants.gov each morning, and this page is that reading. Describe your organization once and the grants that fit arrive in your sheet, CRM, Slack or agent as they are posted.
Key facts
- Opportunity number
- PAR-27-137
- Status
- Forecast
- Posted
- September 10, 2026
- Closes
- May 25, 2027
- Cost sharing
- Not required
- Funding instrument
- Cooperative Agreement
- Category
- Health
- Assistance listing
- 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders
- Contact
- UDN Program Staff · [email protected] · Please contact via email.
Who can apply
- City or township governments
- For profit organizations other than small businesses
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Native American tribal governments (Federally recognized)
- County governments
- Private institutions of higher education
- Public and State controlled institutions of higher education
- Small businesses
- State governments
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Special district governments
- Public housing authorities/Indian housing authorities
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Native American tribal organizations (other than Federally recognized tribal governments)
- Independent school districts
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.
What the agency says
NINDS intends to support multiple clinical Networks of Diagnostic Excellence (NODEs) as part of the next phase of the Undiagnosed Diseases Network (UDN). Unlike prior phases, clinical NODEs are expected to function as geographically distributed regional clinical networks rather than single-site centers. Each clinical NODE would establish and lead a regional network built on existing partnerships with academic medical centers, hospitals, clinics, federally qualified health centers, and other community-based clinical partners to broaden access to specialized diagnostic expertise and extend the reach of the UDN. Clinical NODEs are expected to provide a coordinated, multidisciplinary and participant-centered evaluation of individuals with highly challenging, difficult-to-diagnose conditions. In collaboration with the Network, clinical NODEs will recruit and enroll participants, conduct medical record reviews, make enrollment determinations, communicate review outcomes and recommendations to participants and referring providers, and coordinate the clinical evaluation with local partner sites and referring providers, as appropriate. In addition, clinical NODEs will participate in network collaborations to develop and test innovative, new diagnostic tools and strategies for both genomic and non-genomic conditions, support systematic re-evaluation of unsolved UDN cases, and conduct research to optimize participant access and experience. Clinical NODEs are also expected to participate in network governance and infrastructure; provide training to support consistent implementation of UDN processes and standards; incorporate participant and community input into workflows and engagement strategies, such as through a Community Advisory Board or comparable mechanisms; and monitor site performance. Applications are not being solicited at this time. This Forecast is being published to provide potential applicants time to plan, establish collaborations, formalize regional partnerships, and prepare responsive projects.
Other open grants from the Department of Health and Human Services
| Opportunity | Status | Closes | Award ceiling | Total funding | Record |
|---|---|---|---|---|---|
| Long-term health outcomes of people living with spina bifida CDC-RFA-DD-26-0222 | Open | Oct 26 | $300,000 | $3,000,000 | grants.gov |
| GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed) RFA-HG-27-011 | Open | Oct 30 | $1,250,000 | $2,000,000 | grants.gov |
| GREGoRi Innovation Projects (U01 Clinical Trial Optional) RFA-HG-27-013 | Open | Oct 30 | $500,000 | $7,500,000 | grants.gov |
| GREGoRi Technology Integration Center (U01, Clinical Trials Optional) RFA-HG-27-012 | Open | Oct 30 | $2,250,000 | $3,000,000 | grants.gov |
| HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required) PAR-27-045 | Open | Oct 30 | grants.gov | ||
| Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed) PAR-24-280 | Open | Nov 2 | grants.gov |
All grants open to City or township governments · All grants open to For profit organizations other than small businesses · All grants open to Nonprofits (501(c)(3)) · Everything closing in May 2027
Read from the Grants.gov API, last updated 2026-10-23. The agency's notice on Grants.gov is the official record; check it before you apply.