Data / Federal grants / RFA-DK-28-115
Single Source Competition for Continuation of Understanding and Targeting the Pathophysiology of Youth-Onset Type 2 Diabetes Clinical Centers (U01 Clinical Trial Not Allowed)
National Institutes of Health (Department of Health and Human Services) expects to post this opportunity around February 2, 2027, with applications due around March 10, 2027. It lists 1 award expected, $35 million in total.
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Key facts
- Opportunity number
- RFA-DK-28-115
- Status
- Forecast
- Posted
- August 4, 2026
- Closes
- March 10, 2027
- Expected awards
- 1
- Total funding
- $35,000,000
- Cost sharing
- Not required
- Funding instrument
- Cooperative Agreement
- Category
- Health
- Assistance listing
- 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research
- Contact
- Division of Diabetes, Endocrinology and Metabolic Diseases · [email protected] · [email protected]
Who can apply
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
This is a Single Source competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.
What the agency says
The DISCOVERY of Risk Factors for Type 2 Diabetes in Youth Study is a multi-center longitudinal consortium conducted across 19 clinical sites to identify risk factors and biological mechanisms driving progression to youth-onset type 2 diabetes. The study is actively recruiting and following early pubertal youth at high risk for the disease with longitudinal follow-up currently underway. The current Biostatistics Research Center (BRC) serves as the consortium's central coordinating center, managing protocol implementation, data management, quality assurance, statistical design and analysis, and inter-site and consortium-wide coordination. The BRC has established the robust infrastructure and standardized processes required to support the study and preserve the integrity of the longitudinal dataset. The purpose of this single-source solicitation is to support completion of the scientific objectives of the ongoing DISCOVERY clinical consortium.
Other open grants from the Department of Health and Human Services
| Opportunity | Status | Closes | Award ceiling | Total funding | Record |
|---|---|---|---|---|---|
| Long-term health outcomes of people living with spina bifida CDC-RFA-DD-26-0222 | Open | Oct 26 | $300,000 | $3,000,000 | grants.gov |
| GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed) RFA-HG-27-011 | Open | Oct 30 | $1,250,000 | $2,000,000 | grants.gov |
| GREGoRi Innovation Projects (U01 Clinical Trial Optional) RFA-HG-27-013 | Open | Oct 30 | $500,000 | $7,500,000 | grants.gov |
| GREGoRi Technology Integration Center (U01, Clinical Trials Optional) RFA-HG-27-012 | Open | Oct 30 | $2,250,000 | $3,000,000 | grants.gov |
| HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required) PAR-27-045 | Open | Oct 30 | grants.gov | ||
| Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed) PAR-24-280 | Open | Nov 2 | grants.gov |
· Everything closing in March 2027
Read from the Grants.gov API, last updated 2026-10-23. The agency's notice on Grants.gov is the official record; check it before you apply.