Data / Federal grants / RFA-DK-27-119
Silvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional)
National Institutes of Health (Department of Health and Human Services) is accepting applications until February 10, 2027. It lists awards of up to $750,000, 4 awards expected, $4.8 million in total.
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Key facts
- Opportunity number
- RFA-DK-27-119
- Status
- Posted, open
- Posted
- June 16, 2026
- Closes
- February 10, 2027
- Award ceiling
- $750,000
- Expected awards
- 4
- Total funding
- $4,800,000
- Cost sharing
- Not required
- Funding instrument
- Grant
- Category
- Health
- Assistance listing
- 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research
- Contact
- National Institutes of Health · [email protected] · 301-402-2541
Who can apply
- Special district governments
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- For profit organizations other than small businesses
- Native American tribal governments (Federally recognized)
- Private institutions of higher education
- Independent school districts
- Small businesses
- State governments
- City or township governments
- County governments
- Public and State controlled institutions of higher education
- Native American tribal organizations (other than Federally recognized tribal governments)
- Public housing authorities/Indian housing authorities
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Only institutions at which there is a strong ongoing base of digestive and/or liver diseases-relevant research that relates to the proposed theme of the Center are eligible. The already funded research base must have at least $3 million per year in direct costs of supported research within a proposed theme area that is of primary interest to the NIDDK. These may be a mix of Federal and privately funded research awards or research career development awards. However, at least 30 percent of the total funding contributing to the research base must be secured from the NIDDK. Moreover, enough awards within the research base must be Federal to fulfill the requirement that each Biomedical Research Core must be utilized by a minimum of two federally funded Center members. Training grants, education grants, and fellowship awards are not considered part of the research base funding. Since "Facilities and Administration" costs vary considerably between institutions, these must not be included in the calculation of the research base.Foreign Organizations/International Collaborations:Non-domestic
What the agency says
This Notice of Funding Opportunity (NOFO) invites applications for Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs). The DDRCCs are part of an integrated program of digestive and liver diseases research support provided by the NIDDK. The purpose of this Centers program is to bring together basic and clinical investigators to enhance communication, collaboration, and effectiveness of ongoing research related to digestive and/or liver diseases within the NIDDK's mission. DDRCCs are based on the core concept, whereby shared resources aimed at fostering productivity, synergy, and new research ideas among the funded investigators are supported in a cost-effective manner. Each proposed DDRCC must be organized around a central theme that reflects the focus of the digestive or liver diseases research of the Center members. The central theme must be within the primary mission of the NIDDK, and not thematic areas for which other NIH Institutes or Centers are considered the primary source of NIH funding.
Other open grants from the Department of Health and Human Services
| Opportunity | Status | Closes | Award ceiling | Total funding | Record |
|---|---|---|---|---|---|
| Long-term health outcomes of people living with spina bifida CDC-RFA-DD-26-0222 | Open | Oct 26 | $300,000 | $3,000,000 | grants.gov |
| GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed) RFA-HG-27-011 | Open | Oct 30 | $1,250,000 | $2,000,000 | grants.gov |
| GREGoRi Innovation Projects (U01 Clinical Trial Optional) RFA-HG-27-013 | Open | Oct 30 | $500,000 | $7,500,000 | grants.gov |
| GREGoRi Technology Integration Center (U01, Clinical Trials Optional) RFA-HG-27-012 | Open | Oct 30 | $2,250,000 | $3,000,000 | grants.gov |
| HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required) PAR-27-045 | Open | Oct 30 | grants.gov | ||
| Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed) PAR-24-280 | Open | Nov 2 | grants.gov |
All grants open to Special district governments · All grants open to Nonprofits (501(c)(3)) · All grants open to For profit organizations other than small businesses · Everything closing in February 2027
Read from the Grants.gov API, last updated 2026-10-23. The agency's notice on Grants.gov is the official record; check it before you apply.