Data / Federal grants / RFA-CA-27-003
Radiation Oncology-Biology Integration Network (ROBIN) Centers (U54 Clinical Trial Required)
National Institutes of Health (Department of Health and Human Services) expects to post this opportunity around August 19, 2026, with applications due around January 25, 2027.
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Key facts
- Opportunity number
- RFA-CA-27-003
- Status
- Forecast
- Posted
- June 2, 2026
- Closes
- January 25, 2027
- Cost sharing
- Not required
- Funding instrument
- Cooperative Agreement
- Category
- Health
- Assistance listing
- 93.394 Cancer Detection and Diagnosis Research; 93.395 Cancer Treatment Research
- Contact
- NCI ROBIN RFA · [email protected] · Please contact via e-mail
Who can apply
- For profit organizations other than small businesses
- Native American tribal organizations (other than Federally recognized tribal governments)
- City or township governments
- Public housing authorities/Indian housing authorities
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- State governments
- Small businesses
- Special district governments
- Public and State controlled institutions of higher education
- Independent school districts
- Native American tribal governments (Federally recognized)
- County governments
- Private institutions of higher education
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
What the agency says
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to continue to support the Radiation Oncology-Biology Integration Network (ROBIN) with applications from both new and renewing investigators. This network model will sustain an agile and effective national radiation oncology infrastructure that collectively addresses critical hypothesis-based translational research on the biological basis of responses in cancer patients who undergo radiation treatments. ROBIN supports a collaborative national research network focused on understanding how tumors and normal tissues change biologically during radiation therapy. Because radiation can dynamically alter molecular targets over the course of treatment, the network seeks to generate foundational knowledge that can improve radiation-based cancer care and identify new opportunities for combining radiation with drugs and other therapies. Through multidisciplinary, longitudinal studies, ROBIN centers collect and analyze biospecimens and multimodal data before, during, and after standard-of-care radiation therapy. This work is designed to reveal mechanisms of response, resistance, and toxicity; identify new therapy-induced targets; and determine whether treatment strategies based on initial tumor profiling remain optimal as therapy progresses. The network also strengthens the radiation oncology workforce by integrating expertise in biology, clinical oncology, imaging, dosimetry, omics, biospecimen science, and data science. By sustaining this research infrastructure, NIH aims to accelerate translational discoveries that can inform future clinical trials and improve outcomes for people with cancer.
Other open grants from the Department of Health and Human Services
| Opportunity | Status | Closes | Award ceiling | Total funding | Record |
|---|---|---|---|---|---|
| Long-term health outcomes of people living with spina bifida CDC-RFA-DD-26-0222 | Open | Oct 26 | $300,000 | $3,000,000 | grants.gov |
| GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed) RFA-HG-27-011 | Open | Oct 30 | $1,250,000 | $2,000,000 | grants.gov |
| GREGoRi Innovation Projects (U01 Clinical Trial Optional) RFA-HG-27-013 | Open | Oct 30 | $500,000 | $7,500,000 | grants.gov |
| GREGoRi Technology Integration Center (U01, Clinical Trials Optional) RFA-HG-27-012 | Open | Oct 30 | $2,250,000 | $3,000,000 | grants.gov |
| HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required) PAR-27-045 | Open | Oct 30 | grants.gov | ||
| Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed) PAR-24-280 | Open | Nov 2 | grants.gov |
All grants open to For profit organizations other than small businesses · All grants open to Tribal organizations · All grants open to City or township governments · Everything closing in January 2027
Read from the Grants.gov API, last updated 2026-10-23. The agency's notice on Grants.gov is the official record; check it before you apply.