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Data / Federal grants / PAR-25-100

Pilot Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R34 Clinical Trial Optional)

National Institutes of Health (Department of Health and Human Services) is accepting applications until May 7, 2027.

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Key facts

Opportunity number
PAR-25-100
Status
Posted, open
Posted
December 6, 2024
Closes
May 7, 2027
Cost sharing
Not required
Funding instrument
Grant
Category
Education, Health
Assistance listing
93.279 Drug Use and Addiction Research Programs; None None
Contact
National Institutes of Health · [email protected] · 301-402-2541

Who can apply

  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Native American tribal governments (Federally recognized)
  • For profit organizations other than small businesses
  • Special district governments
  • Private institutions of higher education
  • Independent school districts
  • County governments
  • Public and State controlled institutions of higher education
  • State governments
  • City or township governments
  • Public housing authorities/Indian housing authorities
  • Small businesses
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

What the agency says

This Notice of Funding Opportunity (NOFO) encourages pilot and preliminary research in preparation for larger-scale services research effectiveness trials. Relevant trials may test a wide range of approaches, including interventions, practices, and policies designed to optimize access to, and the quality, effectiveness, affordability and utilization of drug, tobacco, or alcohol use disorder treatments and related services, as well as services for comorbid medical and mental disorder conditions. Relevant approaches may include both those that are novel, and those that are commonly used in practice but lack an evidence base. This NOFO provides resources for assessing the feasibility, acceptability, and utility of these approaches, in addition to usual trial preparation activities.

The notice on Grants.gov Full announcement

Other open grants from the Department of Health and Human Services

All grants open to Tribal organizations · All grants open to Nonprofits (501(c)(3)) · All grants open to Tribal governments · Everything closing in May 2027

Read from the Grants.gov API, last updated 2026-10-23. The agency's notice on Grants.gov is the official record; check it before you apply.