Data / Federal grants / PAR-28-093
Pilot and Feasibility Studies in Preparation for Substance Use and HIV Prevention Intervention and Services Research Trials (R34 Clinical Trial Optional)
National Institutes of Health (Department of Health and Human Services) is accepting applications until July 16, 2029. It lists awards of up to $450,000.
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Key facts
- Opportunity number
- PAR-28-093
- Status
- Posted, open
- Posted
- October 19, 2026
- Closes
- July 16, 2029
- Award ceiling
- $450,000
- Cost sharing
- Not required
- Funding instrument
- Grant
- Category
- Health
- Assistance listing
- 93.279 Drug Use and Addiction Research Programs; 93.310 Trans-NIH Research Support; 93.681 Office of Disease Prevention
- Contact
- National Institutes of Health · [email protected] · 301-402-2541
Who can apply
- Private institutions of higher education
- Native American tribal governments (Federally recognized)
- County governments
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Small businesses
- Native American tribal organizations (other than Federally recognized tribal governments)
- Special district governments
- Public and State controlled institutions of higher education
- Public housing authorities/Indian housing authorities
- City or township governments
- Independent school districts
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- State governments
- For profit organizations other than small businesses
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. See NIH Grants Policy Statement 16.8 Collaborative International Research Awards.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or
What the agency says
The purpose of this notice of funding opportunity (NOFO) is to support pilot and feasibility studies to inform the design and conduct of efficacy, effectiveness, and/or services research trials. Topics may include: 1) developing interventions to prevent substance use, misuse, or progression to substance use disorder; 2) prevention, treatment, or recovery services research, including research addressing comorbid pain and medical and mental health disorders; and 3) HIV eradication research, including implementation science, prevention, treatment and recovery in substance use settings/populations.
Other open grants from the Department of Health and Human Services
| Opportunity | Status | Closes | Award ceiling | Total funding | Record |
|---|---|---|---|---|---|
| Long-term health outcomes of people living with spina bifida CDC-RFA-DD-26-0222 | Open | Oct 26 | $300,000 | $3,000,000 | grants.gov |
| GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed) RFA-HG-27-011 | Open | Oct 30 | $1,250,000 | $2,000,000 | grants.gov |
| GREGoRi Innovation Projects (U01 Clinical Trial Optional) RFA-HG-27-013 | Open | Oct 30 | $500,000 | $7,500,000 | grants.gov |
| GREGoRi Technology Integration Center (U01, Clinical Trials Optional) RFA-HG-27-012 | Open | Oct 30 | $2,250,000 | $3,000,000 | grants.gov |
| HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required) PAR-27-045 | Open | Oct 30 | grants.gov | ||
| Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed) PAR-24-280 | Open | Nov 2 | grants.gov |
All grants open to Private colleges and universities · All grants open to Tribal governments · All grants open to County governments · Everything closing in July 2029
Read from the Grants.gov API, last updated 2026-10-23. The agency's notice on Grants.gov is the official record; check it before you apply.