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Data / Federal grants / PAR-28-045

Opportunities for Collaborative Research with the NIH Intramural Research Program (U01 Clinical Trial Optional)

National Institutes of Health (Department of Health and Human Services) expects to post this opportunity around December 1, 2026, with applications due around February 5, 2027. It lists awards of up to $500,000, 25 awards expected.

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Key facts

Opportunity number
PAR-28-045
Status
Forecast
Posted
July 16, 2026
Closes
February 5, 2027
Award ceiling
$500,000
Expected awards
25
Cost sharing
Not required
Funding instrument
Cooperative Agreement
Category
Health
Assistance listing
93.313 NIH Office of Research on Women's Health
Contact
U01 Program · [email protected] · 301-496-4121

Who can apply

  • City or township governments
  • Small businesses
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Public housing authorities/Indian housing authorities
  • Independent school districts
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Special district governments
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • Native American tribal governments (Federally recognized)
  • County governments
  • Public and State controlled institutions of higher education
  • State governments
  • For profit organizations other than small businesses
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

What the agency says

The goal of this program is to support collaborative translational research projects aligned with NIH efforts to enhance the translation of basic biological discoveries into clinical applications that improve health. It encourages high quality science demonstrating the potential to result in understanding an important disease process or lead to new therapeutic interventions, diagnostics, or prevention strategies within the research interests and priorities of the participating NIH Institutes/Centers (ICs). Specifically, the program seeks to broaden and strengthen translational research collaborations between basic and clinical researchers both within and outside NIH to accelerate and enhance translational science by promoting partnerships between NIH intramural investigators (e.g., those conducting research within the labs and clinics of the NIH) and extramural investigators (e.g., those conducting research in labs outside the NIH), and by providing support for extramural investigators to take advantage of the unique research opportunities available at the NIH by conducting clinical research projects in collaboration with NIH intramural investigators.

The notice on Grants.gov

Other open grants from the Department of Health and Human Services

All grants open to City or township governments · All grants open to Small businesses · All grants open to Nonprofits (501(c)(3)) · Everything closing in February 2027

Read from the Grants.gov API, last updated 2026-10-24. The agency's notice on Grants.gov is the official record; check it before you apply.