Data / Federal grants / PA-25-305
NIH Research Project Grant (Parent R01 Clinical Trial Required)
National Institutes of Health (Department of Health and Human Services) is accepting applications until January 7, 2028.
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Key facts
- Opportunity number
- PA-25-305
- Status
- Posted, open
- Posted
- December 18, 2024
- Closes
- January 7, 2028
- Cost sharing
- Not required
- Funding instrument
- Grant
- Category
- Education, Environment, Food and Nutrition, Health, Income Security and Social Services
- Assistance listing
- 93.113 Environmental Health; 93.143 NIEHS Superfund Hazardous Substances_Basic Research and Education; 93.172 Human Genome Research; 93.173 Research Related to Deafness and Communication Disorders; 93.213 Research and Training in Complementary and Integrative Health; 93.233 National Center on Sleep Disorders Research; 93.242 Mental Health Research Grants; 93.273 Alcohol Research Programs; 93.279 Drug Use and Addiction Research Programs; 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health; 93.307 Minority Health and Health Disparities Research; 93.361 Nursing Research; 93.837 Cardiovascular Diseases Research; 93.838 Lung Diseases Research; 93.839 Blood Diseases and Resources Research; 93.840 Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders; 93.846 Arthritis, Musculoskeletal and Skin Diseases Research; 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research; 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders; 93.855 Allergy and Infectious Diseases Research; 93.859 Biomedical Research and Research Training; 93.865 Child Health and Human Development Extramural Research; 93.866 Aging Research; 93.867 Vision Research; 93.879 Medical Library Assistance; None None
- Contact
- National Institutes of Health · [email protected] · 301-402-2541
Who can apply
- State governments
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- City or township governments
- Native American tribal organizations (other than Federally recognized tribal governments)
- Small businesses
- Public housing authorities/Indian housing authorities
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Special district governments
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Independent school districts
- County governments
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- For profit organizations other than small businesses
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
What the agency says
The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s). This Parent Notice of Funding Opportunity Announcement requires that at lease 1 clinical trial be proposed. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.
Other open grants from the Department of Health and Human Services
| Opportunity | Status | Closes | Award ceiling | Total funding | Record |
|---|---|---|---|---|---|
| Long-term health outcomes of people living with spina bifida CDC-RFA-DD-26-0222 | Open | Oct 26 | $300,000 | $3,000,000 | grants.gov |
| GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed) RFA-HG-27-011 | Open | Oct 30 | $1,250,000 | $2,000,000 | grants.gov |
| GREGoRi Innovation Projects (U01 Clinical Trial Optional) RFA-HG-27-013 | Open | Oct 30 | $500,000 | $7,500,000 | grants.gov |
| GREGoRi Technology Integration Center (U01, Clinical Trials Optional) RFA-HG-27-012 | Open | Oct 30 | $2,250,000 | $3,000,000 | grants.gov |
| HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required) PAR-27-045 | Open | Oct 30 | grants.gov | ||
| Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed) PAR-24-280 | Open | Nov 2 | grants.gov |
All grants open to State governments · All grants open to Nonprofits (501(c)(3)) · All grants open to Private colleges and universities · Everything closing in January 2028
Read from the Grants.gov API, last updated 2026-10-23. The agency's notice on Grants.gov is the official record; check it before you apply.