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Data / Federal grants / PA-27-061

NIH Research Program Projects (Parent P01 Clinical Trial Optional)

National Institutes of Health (Department of Health and Human Services) is accepting applications until May 25, 2029.

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Key facts

Opportunity number
PA-27-061
Status
Posted, open
Posted
October 14, 2026
Closes
May 25, 2029
Cost sharing
Not required
Funding instrument
Grant
Category
Health
Assistance listing
93.113 Environmental Health; 93.172 Human Genome Research; 93.233 National Center on Sleep Disorders Research; 93.273 Alcohol Research Programs; 93.279 Drug Use and Addiction Research Programs; 93.307 Minority Health and Health Disparities Research; 93.313 NIH Office of Research on Women's Health; 93.393 Cancer Cause and Prevention Research; 93.394 Cancer Detection and Diagnosis Research; 93.395 Cancer Treatment Research; 93.396 Cancer Biology Research; 93.399 Cancer Control; 93.837 Cardiovascular Diseases Research; 93.838 Lung Diseases Research; 93.839 Blood Diseases and Resources Research; 93.840 Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders; 93.855 Allergy and Infectious Diseases Research; 93.866 Aging Research; 93.879 Medical Library Assistance
Contact
National Institutes of Health · Email: [email protected] · 301-402-2541

Who can apply

  • Public housing authorities/Indian housing authorities
  • Private institutions of higher education
  • State governments
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • Special district governments
  • Native American tribal governments (Federally recognized)
  • Public and State controlled institutions of higher education
  • County governments
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Independent school districts
  • Small businesses
  • City or township governments
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • For profit organizations other than small businesses

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

What the agency says

Through this Notice of Funding Opportunity (NOFO), the participating NIH Institutes, Centers, and Offices (ICOs) invite applications for the investigator-initiated Program Project (P01). A P01 supports a broadly based, multidisciplinary research program with a specific major scientific objective or theme. The proposed Program Projects are focused on the programmatic interests of one or more of the participating ICOs based on their scientific missions. A program project utilizes research projects with a common central scientific theme, an administrative core, and optional shared resource core(s) to accomplish ICOs' programmatic objectives.

The notice on Grants.gov

Other open grants from the Department of Health and Human Services

All grants open to Public housing authorities/Indian housing authorities · All grants open to Private colleges and universities · All grants open to State governments · Everything closing in May 2029

Read from the Grants.gov API, last updated 2026-10-24. The agency's notice on Grants.gov is the official record; check it before you apply.