Skip to the page

Data / Federal grants / RFA-RM-28-001

NIH Director's Pioneer Award (DP1 Clinical Trial Optional)

National Institutes of Health (Department of Health and Human Services) expects to post this opportunity around March 15, 2027, with applications due around September 9, 2027. It lists awards of up to $700,000, 7 awards expected, $8.2 million in total.

SpecStream is the live web data engine for teams and agents. It reads every open and forecast federal opportunity on Grants.gov each morning, and this page is that reading. Describe your organization once and the grants that fit arrive in your sheet, CRM, Slack or agent as they are posted.

Key facts

Opportunity number
RFA-RM-28-001
Status
Forecast
Posted
September 3, 2026
Closes
September 9, 2027
Award ceiling
$700,000
Award floor
$700,000
Expected awards
7
Total funding
$8,200,000
Cost sharing
Not required
Funding instrument
Grant
Category
Health
Assistance listing
93.310 Trans-NIH Research Support
Contact
NIH Director's Pioneer Award Program · [email protected] · Please contact via e-mail.

Who can apply

  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • State governments
  • Native American tribal governments (Federally recognized)
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • County governments
  • Small businesses
  • Independent school districts
  • Private institutions of higher education
  • City or township governments
  • Public housing authorities/Indian housing authorities
  • Special district governments
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Public and State controlled institutions of higher education
  • For profit organizations other than small businesses
  • Native American tribal organizations (other than Federally recognized tribal governments)

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

What the agency says

The NIH Director's Pioneer Award supports exceptionally creative scientists pursuing bold, innovative research with the potential to transform important areas of science relevant to the NIH mission. Proposed projects must explore new scientific directions that differ substantially from the investigator's current research and from existing work in the field. Applications are welcome across all areas relevant to NIH. The Pioneer Award is part of the NIH Common Fund's High-Risk, High-Reward Research Program .

The notice on Grants.gov

Other open grants from the Department of Health and Human Services

All grants open to Nonprofits (501(c)(3)) · All grants open to State governments · All grants open to Tribal governments · Everything closing in September 2027

Read from the Grants.gov API, last updated 2026-10-23. The agency's notice on Grants.gov is the official record; check it before you apply.