Data / Federal grants / RFA-DA-28-002
NIDA Avenir Program: Fundamental Mechanistic Research in Addiction Science
National Institutes of Health (Department of Health and Human Services) expects to post this opportunity around February 1, 2027, with applications due around May 26, 2027. It lists awards of up to $375,000, 5 awards expected, $3 million in total.
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Key facts
- Opportunity number
- RFA-DA-28-002
- Status
- Forecast
- Posted
- September 10, 2026
- Closes
- May 26, 2027
- Award ceiling
- $375,000
- Expected awards
- 5
- Total funding
- $3,000,000
- Cost sharing
- Not required
- Funding instrument
- Grant
- Category
- Health
- Assistance listing
- 93.279 Drug Use and Addiction Research Programs
- Contact
- National Institute on Drug Abuse (NIDA · [email protected] · Please contact via e-mail.
Who can apply
- State governments
- Independent school districts
- County governments
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Public and State controlled institutions of higher education
- Special district governments
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- City or township governments
- Private institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Native American tribal organizations (other than Federally recognized tribal governments)
- Small businesses
- For profit organizations other than small businesses
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;
What the agency says
Avenir, the French word for "future," reflects NIDA's commitment to developing the next generation of leaders in addiction science. Since 2015, the Avenir Program has supported exceptionally creative early stage investigators (ESIs) in launching innovative research programs. NIDA is now expanding this program to support bold mechanistic research across a broader range of addiction science, including genetic, epigenetic, molecular, cellular, circuit, chemical, pharmacological, behavioral, and cognitive processes relevant to Substance Use Disorders (SUDs). This initiative is intended to catalyze high-risk, high-reward research and attract outstanding new investigators, including those from outside the addiction field. Applications proposing novel, unconventional, or interdisciplinary wet-lab and/or data science approaches to advance understanding of the mechanisms underlying SUDs are encouraged. The Avenir Program is designed for ESIs who may lack the preliminary data needed for an R01 application but propose high-impact research and show strong potential to become future leaders in fundamental mechanistic addiction science. Grant authorities that allow NIDA to forecast this opportunity are 42 U.S.C. §§ 241 and 284.
Other open grants from the Department of Health and Human Services
| Opportunity | Status | Closes | Award ceiling | Total funding | Record |
|---|---|---|---|---|---|
| Long-term health outcomes of people living with spina bifida CDC-RFA-DD-26-0222 | Open | Oct 26 | $300,000 | $3,000,000 | grants.gov |
| GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed) RFA-HG-27-011 | Open | Oct 30 | $1,250,000 | $2,000,000 | grants.gov |
| GREGoRi Innovation Projects (U01 Clinical Trial Optional) RFA-HG-27-013 | Open | Oct 30 | $500,000 | $7,500,000 | grants.gov |
| GREGoRi Technology Integration Center (U01, Clinical Trials Optional) RFA-HG-27-012 | Open | Oct 30 | $2,250,000 | $3,000,000 | grants.gov |
| HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required) PAR-27-045 | Open | Oct 30 | grants.gov | ||
| Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed) PAR-24-280 | Open | Nov 2 | grants.gov |
All grants open to State governments · All grants open to Independent school districts · All grants open to County governments · Everything closing in May 2027
Read from the Grants.gov API, last updated 2026-10-24. The agency's notice on Grants.gov is the official record; check it before you apply.