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Data / Federal grants / PAR-25-081

National Cancer Institute's Investigator-Initiated Early Phase Clinical Trials for Cancer Treatment and Diagnosis (R01 Clinical Trial Required)

National Institutes of Health (Department of Health and Human Services) is accepting applications until January 7, 2027. It lists awards of up to $499,999, $499,999 in total.

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Key facts

Opportunity number
PAR-25-081
Status
Posted, open
Posted
November 12, 2024
Closes
January 7, 2027
Award ceiling
$499,999
Total funding
$499,999
Cost sharing
Not required
Funding instrument
Grant
Category
Education, Health
Assistance listing
93.393 Cancer Cause and Prevention Research; 93.394 Cancer Detection and Diagnosis Research; 93.395 Cancer Treatment Research; 93.399 Cancer Control; None None
Contact
National Institutes of Health · [email protected] · 301-402-2541

Who can apply

  • State governments
  • Public housing authorities/Indian housing authorities
  • Independent school districts
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • For profit organizations other than small businesses
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Native American tribal governments (Federally recognized)
  • Private institutions of higher education
  • Small businesses
  • Public and State controlled institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • County governments
  • City or township governments
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Special district governments

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

What the agency says

Through this Notice of Funding Opportunity, the National Cancer Institute (NCI) seeks research projects that implement early phase (Phase 0, I, and II) investigator-initiated clinical trials focused on cancer-targeted diagnostic and therapeutic interventions of direct relevance to the research mission of DCTD and OHAM. The proposed project must involve at least 1 clinical trial related to the scientific interests of one or more of the following research programs: Cancer Therapy Evaluation Program, Cancer Imaging Program, Cancer Diagnosis Program, Radiation Research Program, Complementary and Alternative Medicine Program and/or the HIV and AIDS Malignancies Research Programs. Applicants may propose to conduct an early phase trial by itself, or in combination with another research aim(s) as appropriate.

The notice on Grants.gov Full announcement

Other open grants from the Department of Health and Human Services

All grants open to State governments · All grants open to Public housing authorities/Indian housing authorities · All grants open to Independent school districts · Everything closing in January 2027

Read from the Grants.gov API, last updated 2026-10-23. The agency's notice on Grants.gov is the official record; check it before you apply.