Data / Federal grants / RFA-IP-27-026
Improving Protection against Influenza and Other Respiratory Pathogens: the US Flu VE Network
Centers for Disease Control and Prevention - ERA (Department of Health and Human Services) expects to post this opportunity around October 30, 2026, with applications due around December 31, 2026. It lists awards of up to $3.6 million, 6 awards expected, $75.3 million in total.
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Key facts
- Opportunity number
- RFA-IP-27-026
- Status
- Forecast
- Posted
- July 28, 2026
- Closes
- December 31, 2026
- Award ceiling
- $3,550,000
- Award floor
- $1,350,000
- Expected awards
- 6
- Total funding
- $75,250,000
- Cost sharing
- Not required
- Funding instrument
- Cooperative Agreement
- Category
- Health
- Assistance listing
- 93.185 Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects
- Contact
- Jocelyn Patterson Mosley · [email protected] · 404-639-6437
Who can apply
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- For profit organizations other than small businesses
- Private institutions of higher education
- Independent school districts
- Public housing authorities/Indian housing authorities
- City or township governments
- Native American tribal governments (Federally recognized)
- Special district governments
- Public and State controlled institutions of higher education
- Native American tribal organizations (other than Federally recognized tribal governments)
- State governments
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- County governments
What the agency says
The purpose of this notice of funding opportunity (NOFO) is to continue the work of the US Influenza Vaccine Effectiveness (Flu VE) Network. Influenza and other respiratory pathogens are important causes of morbidity, mortality, and healthcare burden across the age spectrum. This network provides evidence needed to improve the effectiveness of influenza and other respiratory pathogen vaccines. You would propose work under this NOFO to include: 1) annual VE and correlates of protection surveillance from active enrollment and systematic respiratory pathogen testing of outpatients; 2) electronic acute respiratory illness and VE surveillance; 3) household transmission research studies; and 4) immunogenicity research studies. This is a multi-component NOFO of Component A, B, C and D. The anticipated award number for each component is: five for Component A (VE and correlates of protection), one for Component B (Coordination and surge capacity), two for Component C (Household transmission studies) and three for Component D (Immunogenicity studies). You are required to apply for either Component A (VE and correlates of protection) or B (Coordination and surge capacity) but not both. If you apply for Component A, you may also apply for optional Components C (Household transmission studies) or D (Immunogenicity studies) or both. If you apply for Component B, you may also apply for optional Component D. We expect to fund 5 sites for Component A up to $1,800,000 per site annually and 1 site for Component B up to $1,800,000 annually. Up to 2 sites selected for Component A may be awarded optional Component C to be funded up to $1,00,000 per site annually. Up to 3 sites selected for either Components A or B may be awarded optional Component D to be funded up to $750,000 per site annually.
Other open grants from the Department of Health and Human Services
| Opportunity | Status | Closes | Award ceiling | Total funding | Record |
|---|---|---|---|---|---|
| Long-term health outcomes of people living with spina bifida CDC-RFA-DD-26-0222 | Open | Oct 26 | $300,000 | $3,000,000 | grants.gov |
| GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed) RFA-HG-27-011 | Open | Oct 30 | $1,250,000 | $2,000,000 | grants.gov |
| GREGoRi Innovation Projects (U01 Clinical Trial Optional) RFA-HG-27-013 | Open | Oct 30 | $500,000 | $7,500,000 | grants.gov |
| GREGoRi Technology Integration Center (U01, Clinical Trials Optional) RFA-HG-27-012 | Open | Oct 30 | $2,250,000 | $3,000,000 | grants.gov |
| HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required) PAR-27-045 | Open | Oct 30 | grants.gov | ||
| Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed) PAR-24-280 | Open | Nov 2 | grants.gov |
All grants open to Nonprofits (501(c)(3)) · All grants open to For profit organizations other than small businesses · All grants open to Private colleges and universities · Everything closing in December 2026
Read from the Grants.gov API, last updated 2026-10-23. The agency's notice on Grants.gov is the official record; check it before you apply.