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Data / Federal grants / RFA-AI-27-018

Implementation Science to Advance HIV Prevention, Treatment, and Care (R61/R33 Clinical Trial Optional)

National Institutes of Health (Department of Health and Human Services) is accepting applications until June 20, 2029. It lists 10 awards expected, $7 million in total.

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Key facts

Opportunity number
RFA-AI-27-018
Status
Posted, open
Posted
October 6, 2026
Closes
June 20, 2029
Expected awards
10
Total funding
$7,000,000
Cost sharing
Not required
Funding instrument
Grant
Category
Health
Assistance listing
93.121 Oral Diseases and Disorders Research; 93.233 National Center on Sleep Disorders Research; 93.242 Mental Health Research Grants; 93.273 Alcohol Research Programs; 93.279 Drug Use and Addiction Research Programs; 93.307 Minority Health and Health Disparities Research; 93.310 Trans-NIH Research Support; 93.313 NIH Office of Research on Women's Health; 93.361 Nursing Research; 93.393 Cancer Cause and Prevention Research; 93.394 Cancer Detection and Diagnosis Research; 93.399 Cancer Control; 93.837 Cardiovascular Diseases Research; 93.838 Lung Diseases Research; 93.839 Blood Diseases and Resources Research; 93.840 Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders; 93.846 Arthritis, Musculoskeletal and Skin Diseases Research; 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research; 93.855 Allergy and Infectious Diseases Research; 93.865 Child Health and Human Development Extramural Research; 93.866 Aging Research; 93.879 Medical Library Assistance
Contact
National Institutes of Health · [email protected] · 301-402-2541

Who can apply

  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • State governments
  • Public and State controlled institutions of higher education
  • Small businesses
  • County governments
  • Public housing authorities/Indian housing authorities
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • Special district governments
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • For profit organizations other than small businesses
  • City or township governments
  • Private institutions of higher education
  • Native American tribal governments (Federally recognized)
  • Independent school districts

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

What the agency says

The purpose of this notice of funding opportunity (NOFO) is to support implementation research on strategies to improve the uptake, implementation, sustainment, scale and/or spread of evidence-based prevention, treatment, and care interventions in communities in the U.S. significantly impacted by HIV. Projects should be large in scale with high potential for research and public health impact. Specifically, large single site studies, multi-site studies, and comparative studies are encouraged as scientifically appropriate.

The notice on Grants.gov

Other open grants from the Department of Health and Human Services

All grants open to Nonprofits without 501(c)(3) status · All grants open to State governments · All grants open to Public colleges and universities · Everything closing in June 2029

Read from the Grants.gov API, last updated 2026-10-24. The agency's notice on Grants.gov is the official record; check it before you apply.