Data / Federal grants / RFA-AI-28-011
Immune Drivers of Autoimmune Disease
National Institutes of Health (Department of Health and Human Services) expects to post this opportunity around February 26, 2027, with applications due around June 11, 2027. It lists $3.6 million in total.
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Key facts
- Opportunity number
- RFA-AI-28-011
- Status
- Forecast
- Posted
- September 24, 2026
- Closes
- June 11, 2027
- Total funding
- $3,600,000
- Cost sharing
- Not required
- Funding instrument
- Cooperative Agreement
- Category
- Health
- Assistance listing
- 93.855 Allergy and Infectious Diseases Research
- Contact
- Division of Allergy, Immunology, and Transplantation · [email protected] · Please contact via email.
Who can apply
- Public and State controlled institutions of higher education
- Public housing authorities/Indian housing authorities
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- County governments
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Private institutions of higher education
- Independent school districts
- Small businesses
- State governments
- Native American tribal organizations (other than Federally recognized tribal governments)
- City or township governments
- Native American tribal governments (Federally recognized)
- Special district governments
- For profit organizations other than small businesses
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
What the agency says
The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission through the continued support of the Immune Drivers of Autoimmune Disease (IDAD) network. This network aims to understand the earliest steps and triggers leading to autoimmunity and flare in humans, with the vision of ultimately preventing autoimmune disease. Priorities include discovering pre-clinical immune mechanisms, developing autoimmunity risk and staging prediction tools and biomarkers, building preclinical cohorts, leveraging remote recruitment and sampling, and artificial intelligence (AI)/big data. This complex, sustained collaboration relies on shared infrastructure to identify common triggers, pathways, and prevention opportunities. An Infrastructure Opportunity Fund (IOF) will be included in the initiative to provide the network the opportunity to conduct collaborative research projects. An IDAD Network Coordinating Center (NCC) will be responsible for administering the IOF and supporting additional coordinating activities amongst IDAD awardees, including the organization of Steering Committee meetings, resource sharing, data harmonization, sample sharing, and administering the IOF. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 2.
Other open grants from the Department of Health and Human Services
| Opportunity | Status | Closes | Award ceiling | Total funding | Record |
|---|---|---|---|---|---|
| Long-term health outcomes of people living with spina bifida CDC-RFA-DD-26-0222 | Open | Oct 26 | $300,000 | $3,000,000 | grants.gov |
| GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed) RFA-HG-27-011 | Open | Oct 30 | $1,250,000 | $2,000,000 | grants.gov |
| GREGoRi Innovation Projects (U01 Clinical Trial Optional) RFA-HG-27-013 | Open | Oct 30 | $500,000 | $7,500,000 | grants.gov |
| GREGoRi Technology Integration Center (U01, Clinical Trials Optional) RFA-HG-27-012 | Open | Oct 30 | $2,250,000 | $3,000,000 | grants.gov |
| HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required) PAR-27-045 | Open | Oct 30 | grants.gov | ||
| Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed) PAR-24-280 | Open | Nov 2 | grants.gov |
All grants open to Public colleges and universities · All grants open to Public housing authorities/Indian housing authorities · All grants open to Nonprofits (501(c)(3)) · Everything closing in June 2027
Read from the Grants.gov API, last updated 2026-10-23. The agency's notice on Grants.gov is the official record; check it before you apply.