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Data / Federal grants / PAS-28-073

HIV Prevention and Alcohol (R61/R33 Clinical Trials Optional)

National Institutes of Health (Department of Health and Human Services) expects to post this opportunity around July 7, 2027, with applications due around September 7, 2027.

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Key facts

Opportunity number
PAS-28-073
Status
Forecast
Posted
October 1, 2026
Closes
September 7, 2027
Cost sharing
Not required
Funding instrument
Grant
Category
Health
Assistance listing
93.273 Alcohol Research Programs
Contact
HIV/AIDS and Alcohol Research Program · [email protected] · 301-402-0332

Who can apply

  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Private institutions of higher education
  • City or township governments
  • Special district governments
  • Small businesses
  • State governments
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • County governments
  • Public housing authorities/Indian housing authorities
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • For profit organizations other than small businesses
  • Independent school districts
  • Public and State controlled institutions of higher education

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.

What the agency says

This Notice of Funding Opportunity (NOFO) uses a R61/R33 Phased Innovation Award to support milestone-driven research that advances innovative HIV prevention interventions from development and feasibility testing to larger-scale efficacy, effectiveness, implementation, and dissemination studies. The R61 phase will support the development, refinement, adaptation, and pilot testing of novel or enhanced HIV prevention and treatment strategies, including studies designed to address key scientific, operational, or implementation questions necessary to establish feasibility and readiness for larger-scale evaluation. Projects may generate evidence needed to optimize intervention design, delivery, and implementation in diverse populations and settings. The R33 phase will support expanded testing of interventions and implementation strategies that have successfully met R61 milestones. Studies may evaluate effectiveness, implementation, scalability, sustainability, clinical management, or delivery of HIV prevention interventions that include integrated approaches addressing alcohol use and related comorbidities.

The notice on Grants.gov

Other open grants from the Department of Health and Human Services

All grants open to Tribal governments · All grants open to Tribal organizations · All grants open to Private colleges and universities · Everything closing in September 2027

Read from the Grants.gov API, last updated 2026-10-23. The agency's notice on Grants.gov is the official record; check it before you apply.