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Data / Federal grants / RFA-AI-28-003

HIV/AIDS Clinical Trials Network Statistical and Data Management Centers

National Institutes of Health (Department of Health and Human Services) expects to post this opportunity around August 25, 2026, with applications due around January 22, 2027.

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Key facts

Opportunity number
RFA-AI-28-003
Status
Forecast
Posted
April 8, 2026
Closes
January 22, 2027
Cost sharing
Not required
Funding instrument
Cooperative Agreement
Category
Health
Assistance listing
93.310 Trans-NIH Research Support; 93.855 Allergy and Infectious Diseases Research
Contact
Division of AIDS · [email protected] · Please contact via e-mail.

Who can apply

  • Small businesses
  • State governments
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • For profit organizations other than small businesses
  • Independent school districts
  • County governments
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • City or township governments
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Special district governments
  • Public housing authorities/Indian housing authorities

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.

What the agency says

The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance the National Institutes of Health (NIH) mission by supporting four Clinical Trials Networks (CTNs) each comprised of a Leadership and Operations Center, Statistical and Data Management Center (SDMC), and Laboratory Center (LC) working with Clinical Trials Units (CTUs), to advance prevention, treatment, and implementation research on HIV and HIV-associated diseases. This NOFO will solicit applications for up to four SDMCs to provide leadership for developing and implementing each CTN research agenda with the goal of ending the HIV epidemic. Each SDMC will coordinate study design and execution, including data collection, monitoring, and analyses. SDMCs manage clinical and laboratory data submitted by CTUs and the LC ensuring data quality, regulatory compliance, and continual reporting of protocol and site performance. SDMCs foster innovative trial design and statistical methods, statistical and data practices harmonization, and ensure validated systems for data capture and integration, according to NIH data sharing policies. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

The notice on Grants.gov

Other open grants from the Department of Health and Human Services

All grants open to Small businesses · All grants open to State governments · All grants open to Private colleges and universities · Everything closing in January 2027

Read from the Grants.gov API, last updated 2026-10-23. The agency's notice on Grants.gov is the official record; check it before you apply.