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Data / Federal grants / RFA-AT-25-003

HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)

National Institutes of Health (Department of Health and Human Services) is accepting applications until November 23, 2026. It lists awards of up to $375,000.

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Key facts

Opportunity number
RFA-AT-25-003
Status
Posted, open
Posted
January 8, 2025
Closes
November 23, 2026
Award ceiling
$375,000
Cost sharing
Not required
Funding instrument
Grant
Category
Health, Income Security and Social Services
Assistance listing
93.121 Oral Diseases and Disorders Research; 93.213 Research and Training in Complementary and Integrative Health; 93.273 Alcohol Research Programs; 93.846 Arthritis, Musculoskeletal and Skin Diseases Research; 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders; 93.865 Child Health and Human Development Extramural Research; 93.866 Aging Research; None None
Contact
National Institutes of Health · [email protected] · 301-402-2541

Who can apply

  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • Public and State controlled institutions of higher education
  • Private institutions of higher education

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) ; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

What the agency says

The purpose of this initiative is to: (1) support the efforts by R15-eligible Principal Investigators (PIs) to conduct rigorous basic and/or mechanistic pain research projects; (2) promote integrated, interdisciplinary research partnerships between R15-eligible PIs and additional investigators from U.S. domestic institutions, and (3) enhance the pain research environment at the R15-eligible institution for health professional trainees or undergraduate and/or graduate students by actively engaging them in the proposed pain research projects.

The notice on Grants.gov Full announcement

Other open grants from the Department of Health and Human Services

All grants open to Public colleges and universities · All grants open to Private colleges and universities · Everything closing in November 2026

Read from the Grants.gov API, last updated 2026-10-23. The agency's notice on Grants.gov is the official record; check it before you apply.