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Data / Federal grants / PAR-25-321

Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Optional)

National Institutes of Health (Department of Health and Human Services) is accepting applications until January 7, 2028.

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Key facts

Opportunity number
PAR-25-321
Status
Posted, open
Posted
December 10, 2024
Closes
January 7, 2028
Cost sharing
Not required
Funding instrument
Grant
Category
Education, Health
Assistance listing
93.393 Cancer Cause and Prevention Research; 93.394 Cancer Detection and Diagnosis Research; 93.395 Cancer Treatment Research; 93.396 Cancer Biology Research; 93.399 Cancer Control; None None
Contact
National Institutes of Health · [email protected] · 301-402-2541

Who can apply

  • County governments
  • Public housing authorities/Indian housing authorities
  • State governments
  • Independent school districts
  • Public and State controlled institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • City or township governments
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Special district governments
  • Native American tribal governments (Federally recognized)
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • For profit organizations other than small businesses
  • Small businesses
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

What the agency says

Through this engineering-oriented Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to encourage submissions of exploratory/developmental Bioengineering Research Grant (EBRG) applications to demonstrate feasibility and potential utility of new capabilities or improvements in quality, speed, efficacy, operability, costs, and/or accessibility of solutions to problems in basic biomedical, pre-clinical, or clinical research, clinical care delivery, or accessibility.

The notice on Grants.gov Full announcement

Other open grants from the Department of Health and Human Services

All grants open to County governments · All grants open to Public housing authorities/Indian housing authorities · All grants open to State governments · Everything closing in January 2028

Read from the Grants.gov API, last updated 2026-10-23. The agency's notice on Grants.gov is the official record; check it before you apply.