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Data / Federal grants / RFA-CA-28-001

Early-Stage Innovative Technology Development for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)

National Institutes of Health (Department of Health and Human Services) expects to post this opportunity around January 15, 2027, with applications due around June 4, 2027. It lists awards of up to $150,000, 23 awards expected, $5.4 million in total.

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Key facts

Opportunity number
RFA-CA-28-001
Status
Forecast
Posted
July 14, 2026
Closes
June 4, 2027
Award ceiling
$150,000
Expected awards
23
Total funding
$5,400,000
Cost sharing
Not required
Funding instrument
Grant
Category
Health
Assistance listing
93.394 Cancer Detection and Diagnosis Research
Contact
IMAT Program Contact · [email protected] · 240-255-0917

Who can apply

  • Native American tribal organizations (other than Federally recognized tribal governments)
  • For profit organizations other than small businesses
  • City or township governments
  • Public and State controlled institutions of higher education
  • Private institutions of higher education
  • Independent school districts
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • State governments
  • Native American tribal governments (Federally recognized)
  • Small businesses
  • County governments
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Special district governments
  • Public housing authorities/Indian housing authorities
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

What the agency says

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits grant applications proposing to develop innovative technologies for cancer research or clinical care. The emphasis of this NOFO is on early-stage projects proposing proof-of-concept/pilot studies to test the technical feasibility of the proposed method, tool, assay, platform, or instrument.  Well-suited applications must offer a high degree of technical innovation and the potential to accelerate and/or enhance research in the areas of cancer biology, early detection and screening, clinical diagnosis, treatment, cancer control, and/or epidemiology. Projects that are in-scope include technologies with new or significantly improved technical capabilities to measure, analyze, model, or interrogate cancer-related systems. These may include, but are not limited to, advanced molecular and cellular analysis platforms, multi-omic and spatial profiling methods, imaging and sensing technologies, immuno-engineering approaches, and innovations in biospecimen processing, modeling, and quality assessment. Technologies proposed for development may have potential for widespread applicability but must be focused in this proposal on cancer applications.  This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program.

The notice on Grants.gov

Other open grants from the Department of Health and Human Services

All grants open to Tribal organizations · All grants open to For profit organizations other than small businesses · All grants open to City or township governments · Everything closing in June 2027

Read from the Grants.gov API, last updated 2026-10-24. The agency's notice on Grants.gov is the official record; check it before you apply.