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Data / Federal grants / PAR-25-273

Development of Animal Models and Related Biological Materials for Research (R21 Clinical Trial Not Allowed)

National Institutes of Health (Department of Health and Human Services) is accepting applications until January 7, 2028. It lists awards of up to $200,000, $200,000 in total.

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Key facts

Opportunity number
PAR-25-273
Status
Posted, open
Posted
November 15, 2024
Closes
January 7, 2028
Award ceiling
$200,000
Total funding
$200,000
Cost sharing
Not required
Funding instrument
Grant
Category
Health
Assistance listing
93.351 Research Infrastructure Programs; None None
Contact
National Institutes of Health · [email protected] · 301-402-2541

Who can apply

  • County governments
  • For profit organizations other than small businesses
  • Native American tribal governments (Federally recognized)
  • Small businesses
  • Special district governments
  • Public and State controlled institutions of higher education
  • Independent school districts
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • Public housing authorities/Indian housing authorities
  • State governments
  • City or township governments
  • Native American tribal organizations (other than Federally recognized tribal governments)

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

What the agency says

This notice of funding opportunity (NOFO) encourages innovative research to develop, improve, characterize, and preserve animal models as well as animal model related biological materials, technologies, and new approach methodologies (NAMs) for studies relevant to human health and disease. This NOFO also seeks projects aimed at improving the diagnosis and control of diseases that could confound or interfere with animal use in biomedical research. The proposed project must have broad applicability to multiple NIH Institutes or Centers (ICs) to align with the NIH-wide mission of the Office of Research Infrastructure Programs (ORIP). The proposed studies must include animal models and explore multiple body systems or multiple categories of diseases. Applications that develop models focused on a specific disease or area of research, or only propose studies primarily relevant to a single NIH IC, will be considered not acceptable to this NOFO and will be withdrawn.

The notice on Grants.gov Full announcement

Other open grants from the Department of Health and Human Services

All grants open to County governments · All grants open to For profit organizations other than small businesses · All grants open to Tribal governments · Everything closing in January 2028

Read from the Grants.gov API, last updated 2026-10-24. The agency's notice on Grants.gov is the official record; check it before you apply.