Data / Federal grants / CDC-RFA-PS-27-0008
Controlling and Preventing STIs in US Health Departments (CAP-STIs)
Centers for Disease Control - NCHHSTP (Department of Health and Human Services) expects to post this opportunity around November 10, 2026, with applications due around January 11, 2027. It lists 59 awards expected, $500 million in total.
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Key facts
- Opportunity number
- CDC-RFA-PS-27-0008
- Status
- Forecast
- Posted
- May 11, 2026
- Closes
- January 11, 2027
- Expected awards
- 59
- Total funding
- $500,000,000
- Cost sharing
- Not required
- Funding instrument
- Cooperative Agreement
- Category
- Health
- Assistance listing
- 93.977 Sexually Transmitted Diseases (STD) Prevention and Control Grants
- Contact
- Mary McFarland · [email protected] · 404.639.8309
Who can apply
- County governments
- Special district governments
- State governments
- City or township governments
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
All fifty (50) states, the District of Columbia, the US Virgin Islands and Puerto Rico are eligible to apply. To ensure implementation of STI control and prevention nationwide, CDC intends to fund all fifty states, the District of Columbia, the US Virgin Islands and Puerto Rico, non-competitively, according to a funding formula based on the respective jurisdiction"s population & morbidity of three reportable STIs (chlamydia, gonorrhea and primary & secondary syphilis).Section 318(c) of the Public Health Services Act, 42 USC 247c(c), provides that the Secretary of HHS may provide funding to "States and, in consultation with the State health authority, to political subdivisions of States..." to conduct STI prevention & control projects. This language allows CDC to fund cities in addition to their respective states. Under the previous STI prevention & control funding opportunity PS19-1901 (& prior to that, PS14-1402), CDC funded the following cities based upon population, STI morbidity & organizational capacity: New York City, Philadelphia, Baltimore, Chicago, Los Angeles & San Francisco.To maximize the efficiency of program delivery, CDC may again fund a limited number of cities unde
What the agency says
CDC is funding programs that track, prevent, and control sexually transmitted infections (STI) in state, district, territorial, and city or county health departments. The purpose of this NOFO is to track, prevent, and control three common STIs: syphilis, gonorrhea, and chlamydia. The NOFO supports the goals of the Sexually Transmitted Infections National Strategic Plan 2021-2025: Prevent new STIs. Improve the health of people by reducing adverse outcomes of STIs. Implement STI prevention technology and innovations more quickly. Reduce the impact of STIs in areas or populations disproportionately impacted by STIs. Achieve integrated, coordinated efforts that address the STI epidemic. Local surveillance data will determine the priority populations for this NOFO. Each program should focus on populations that are disproportionately impacted by STI transmission. To be successful with this NOFO, you will need to collaborate with partners to address interconnected comorbidities and sexual health.
Other open grants from the Department of Health and Human Services
| Opportunity | Status | Closes | Award ceiling | Total funding | Record |
|---|---|---|---|---|---|
| Long-term health outcomes of people living with spina bifida CDC-RFA-DD-26-0222 | Open | Oct 26 | $300,000 | $3,000,000 | grants.gov |
| GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed) RFA-HG-27-011 | Open | Oct 30 | $1,250,000 | $2,000,000 | grants.gov |
| GREGoRi Innovation Projects (U01 Clinical Trial Optional) RFA-HG-27-013 | Open | Oct 30 | $500,000 | $7,500,000 | grants.gov |
| GREGoRi Technology Integration Center (U01, Clinical Trials Optional) RFA-HG-27-012 | Open | Oct 30 | $2,250,000 | $3,000,000 | grants.gov |
| HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required) PAR-27-045 | Open | Oct 30 | grants.gov | ||
| Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed) PAR-24-280 | Open | Nov 2 | grants.gov |
All grants open to County governments · All grants open to Special district governments · All grants open to State governments · Everything closing in January 2027
Read from the Grants.gov API, last updated 2026-10-23. The agency's notice on Grants.gov is the official record; check it before you apply.