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Data / Federal grants / PAR-25-145

Clinical Characterization of Cancer Therapy-induced Adverse Sequelae and Mechanism-based Interventional Strategies (R01 Clinical Trial Optional)

National Institutes of Health (Department of Health and Human Services) is accepting applications until January 7, 2028.

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Key facts

Opportunity number
PAR-25-145
Status
Posted, open
Posted
November 6, 2024
Closes
January 7, 2028
Cost sharing
Not required
Funding instrument
Grant
Category
Education, Health
Assistance listing
93.393 Cancer Cause and Prevention Research; None None
Contact
National Institutes of Health · [email protected] · 301-402-2541

Who can apply

  • Private institutions of higher education
  • Special district governments
  • Public and State controlled institutions of higher education
  • Public housing authorities/Indian housing authorities
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • For profit organizations other than small businesses
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Native American tribal governments (Federally recognized)
  • City or township governments
  • Small businesses
  • County governments
  • State governments
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • Independent school districts

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

What the agency says

The purpose of this Funding Opportunity Announcement (FOA) is to support collaborative research projects designed to address adverse sequelae of cancer therapies that persist and become chronic comorbidities or develop as delayed posttreatment effects. This FOA supports basic, translational, and clinical research projects that seek to identify the mechanisms of therapy-induced adverse sequelae, clinically characterize the adverse sequelae, or translate the mechanistic understanding into therapeutic approaches to prevent or minimize the development of long-term sequelae. Research projects should focus on mechanistic studies with translational endpoints and longitudinal clinical phenotyping to identify and validate clinical endpoints (biomarkers, imaging, patient-reported outcomes, or combined elements) for future use in clinical trials that will evaluate the efficacy of interventions designed to prevent or reduce specific adverse sequelae.

The notice on Grants.gov Full announcement

Other open grants from the Department of Health and Human Services

All grants open to Private colleges and universities · All grants open to Special district governments · All grants open to Public colleges and universities · Everything closing in January 2028

Read from the Grants.gov API, last updated 2026-10-23. The agency's notice on Grants.gov is the official record; check it before you apply.