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Data / Federal grants / RFA-AI-28-031

Centers for Structural Biology of HIV and Other Infectious Diseases (U54 Clinical Trial Not Allowed)

National Institutes of Health (Department of Health and Human Services) is accepting applications until May 28, 2027. It lists awards of up to $3.5 million, $33 million in total.

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Key facts

Opportunity number
RFA-AI-28-031
Status
Posted, open
Posted
October 2, 2026
Closes
May 28, 2027
Award ceiling
$3,500,000
Total funding
$33,000,000
Cost sharing
Not required
Funding instrument
Cooperative Agreement
Category
Health
Assistance listing
93.310 Trans-NIH Research Support; 93.855 Allergy and Infectious Diseases Research
Contact
National Institutes of Health · [email protected] · 301-402-2541

Who can apply

  • Public and State controlled institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • County governments
  • State governments
  • Public housing authorities/Indian housing authorities
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • For profit organizations other than small businesses
  • Special district governments
  • Private institutions of higher education
  • Independent school districts
  • Small businesses
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Native American tribal governments (Federally recognized)
  • City or township governments
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed. NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. See NIH Grants Policy Statement 16.8 Collaborative International Research Awards.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consult

What the agency says

The purpose of this notice of funding opportunity (NOFO) is to  support multidisciplinary consortia of structural biologists, microbiologists, and associated experts to solve complex biological structures related to the prevention, treatment, and cure of HIV and other infectious diseases. Centers are expected to facilitate new collaborations, leverage shared resources, offer services and resources to the research community, and train the next generation of scientists engaged in structural biology of infectious diseases.

The notice on Grants.gov

Other open grants from the Department of Health and Human Services

All grants open to Public colleges and universities · All grants open to Nonprofits without 501(c)(3) status · All grants open to County governments · Everything closing in May 2027

Read from the Grants.gov API, last updated 2026-10-23. The agency's notice on Grants.gov is the official record; check it before you apply.