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Data / Federal grants / RFA-MH-26-170

BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)

National Institutes of Health (Department of Health and Human Services) is accepting applications until February 8, 2027.

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Key facts

Opportunity number
RFA-MH-26-170
Status
Posted, open
Posted
November 15, 2024
Closes
February 8, 2027
Cost sharing
Not required
Funding instrument
Grant
Category
Education, Health, Income Security and Social Services
Assistance listing
93.173 Research Related to Deafness and Communication Disorders; 93.213 Research and Training in Complementary and Integrative Health; 93.242 Mental Health Research Grants; 93.273 Alcohol Research Programs; 93.279 Drug Use and Addiction Research Programs; 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health; 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders; 93.865 Child Health and Human Development Extramural Research; 93.866 Aging Research; 93.867 Vision Research; None None
Contact
National Institutes of Health · [email protected] · 301-402-2541

Who can apply

  • For profit organizations other than small businesses
  • Small businesses
  • County governments
  • Private institutions of higher education
  • Independent school districts
  • Public and State controlled institutions of higher education
  • Public housing authorities/Indian housing authorities
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Native American tribal governments (Federally recognized)
  • City or township governments
  • State governments
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Special district governments
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

What the agency says

The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate novel tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function. The new tools and technologies should inform and/or exploit cell-type and/or circuit-level specificity. Plans for validating the utility of the tool/technology will be an essential feature of a successful application. The development of new genetic and non-genetic tools for delivering genes, proteins and chemicals to cells of interest or approaches that are expected to target specific cell types and/or circuits in the nervous system with greater precision and sensitivity than currently established methods are encouraged. Tools that can be used in a number of species/model organisms rather than those restricted to a single species are highly desired. Applications that provide approaches that break through existing technical barriers to substantially improve current capabilities are highly encouraged.

The notice on Grants.gov Full announcement

Other open grants from the Department of Health and Human Services

All grants open to For profit organizations other than small businesses · All grants open to Small businesses · All grants open to County governments · Everything closing in February 2027

Read from the Grants.gov API, last updated 2026-10-23. The agency's notice on Grants.gov is the official record; check it before you apply.