Data / Federal grants / RFA-HG-28-003
ancient DNA for Modern Genomics (aDMG) Research Projects (U01 Clinical Trials Not Allowed)
National Institutes of Health (Department of Health and Human Services) expects to post this opportunity around August 3, 2027, with applications due around February 1, 2028.
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Key facts
- Opportunity number
- RFA-HG-28-003
- Status
- Forecast
- Posted
- June 2, 2026
- Closes
- February 1, 2028
- Cost sharing
- Not required
- Funding instrument
- Cooperative Agreement
- Category
- Health
- Assistance listing
- 93.172 Human Genome Research
- Contact
- NHGRI Research Funding · [email protected] · Please contact via e-mail.
Who can apply
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Special district governments
- Native American tribal governments (Federally recognized)
- Small businesses
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Public and State controlled institutions of higher education
- For profit organizations other than small businesses
- State governments
- City or township governments
- Public housing authorities/Indian housing authorities
- Private institutions of higher education
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Independent school districts
- County governments
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
What the agency says
The National Human Genome Research Institute (NHGRI) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications to establish an ancient DNA for Modern Genomics (aDMG) program. The goal of aDMG is to establish an ethical resource of ancient and historical human DNA (aDNA) data to advance studies about contemporary human traits and biology. This NOFO aims to solicit applications that will leverage existing and newly generated aDNA data from this consortium to advance the biological and epidemiological understanding of modern human diseases and health-related traits by integrating aDNA with modern human and other species’ data. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U01 activity code. Investigators with expertise and insights into this area of ancient DNA and population genomics are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise in DNA sequencing methods and technology, computational genomics and data science, human evolution, and ancient human populations will be encouraged and these investigators should also begin considering applying for this application.
Other open grants from the Department of Health and Human Services
| Opportunity | Status | Closes | Award ceiling | Total funding | Record |
|---|---|---|---|---|---|
| Long-term health outcomes of people living with spina bifida CDC-RFA-DD-26-0222 | Open | Oct 26 | $300,000 | $3,000,000 | grants.gov |
| GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed) RFA-HG-27-011 | Open | Oct 30 | $1,250,000 | $2,000,000 | grants.gov |
| GREGoRi Innovation Projects (U01 Clinical Trial Optional) RFA-HG-27-013 | Open | Oct 30 | $500,000 | $7,500,000 | grants.gov |
| GREGoRi Technology Integration Center (U01, Clinical Trials Optional) RFA-HG-27-012 | Open | Oct 30 | $2,250,000 | $3,000,000 | grants.gov |
| HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required) PAR-27-045 | Open | Oct 30 | grants.gov | ||
| Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed) PAR-24-280 | Open | Nov 2 | grants.gov |
All grants open to Tribal organizations · All grants open to Nonprofits (501(c)(3)) · All grants open to Special district governments · Everything closing in February 2028
Read from the Grants.gov API, last updated 2026-10-24. The agency's notice on Grants.gov is the official record; check it before you apply.