Data / Federal rules / 2025-10880

Vadescana Double-Stranded RNA; Exemption From the Requirement of a Tolerance

The Environmental Protection Agency published this final rule in the Federal Register on June 16, 2025. It took effect on June 16, 2025.

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What the agency says

This regulation establishes an exemption from the requirement of a tolerance for residues of Vadescana double-stranded (ds) RNA in or on honey and honeycomb if used according to the label and good agricultural practices. GreenLight Biosciences, Inc. submitted a petition to the EPA under the Federal Food, Drug, and Cosmetic Act (FFDCA), requesting an exemption from the requirement of a tolerance. This regulation eliminates the need to establish a maximum permissible level for residues of Vadescana dsRNA (Varroa destructor-Specific Recombinant Double-Stranded Interfering Oligonucleotide EP15) under FFDCA when used in accordance with this exemption.

Key facts

Document number: 2025-10880
Type: Final rule
Action: Final rule
Agency: Environmental Protection Agency
Published: June 16, 2025
Takes effect: June 16, 2025
Dates: This regulation is effective June 16, 2025. Objections and requests for hearings must be received on or before August 15, 2025 and must be filed in accordance with the instructions provided in 40 CFR part 178 (see also Unit I.C. of the SUPPLEMENTARY INFORMATION).
Docket: EPA-HQ-OPP-2023-0561; FRL-12759-01-OCSPP
Code of Federal Regulations: 40 CFR 180
Topics: Administrative practice and procedure; Agricultural commodities; Environmental protection; Pesticides and pests; Reporting and recordkeeping requirements
Pages: 4

The document on federalregister.gov PDF

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Everything from the Environmental Protection Agency · Rules on administrative practice and procedure · Rules on agricultural commodities · Rules on environmental protection · Published in June 2025

Read from the Federal Register API, last updated 2026-10-23. The document on federalregister.gov is the official record; dates and dockets can change through later corrections. Free to reuse with credit to SpecStream under CC BY 4.0.