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Data / Federal rules / 2026-16413

Schedules of Controlled Substances: Temporary Placement of O-Desmethyltramadol in Schedule I

The Drug Enforcement Administration published this final rule in the Federal Register on August 12, 2026. It took effect on August 12, 2026.

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What the agency says

The Drug Enforcement Administration issues this temporary order to schedule O-desmethyltramadol (other names: O-DSMT; desmetramadol; 3-[(1R,2R)-2-[(dimethylamino)methyl]-1- hydroxycyclohexyl]phenol), including its isomers, esters, ethers, salts, and salts of isomers, esters and ethers, in schedule I of the Controlled Substances Act. DEA bases this action on a finding that placing O-DSMT in schedule I is necessary to avoid an imminent hazard to public safety. This order imposes the regulatory controls and administrative, civil, and criminal sanctions applicable to schedule I controlled substances on persons who handle (manufacture, distribute, reverse distribute, import, export, engage in research, conduct instructional activities or chemical analysis with, or possess) or propose to handle O-DSMT.

Key facts

Document number
2026-16413
Type
Final rule
Action
Temporary amendment; temporary scheduling order
Agency
Justice Department; Drug Enforcement Administration
Published
August 12, 2026
Takes effect
August 12, 2026
Dates
This temporary order is effective August 12, 2026, until August 12, 2028. If this order is extended or made permanent, DEA will publish a document in the Federal Register.
Docket
Docket No. DEA-1641
Code of Federal Regulations
21 CFR 1308
Topics
Administrative practice and procedure; Drug traffic control; Reporting and recordkeeping requirements
Pages
6

The document on federalregister.gov PDF

Other documents from the Drug Enforcement Administration

Everything from the Drug Enforcement Administration · Rules on administrative practice and procedure · Rules on drug traffic control · Rules on reporting and recordkeeping requirements · Published in August 2026

Read from the Federal Register API, last updated 2026-10-23. The document on federalregister.gov is the official record; dates and dockets can change through later corrections. Free to reuse with credit to SpecStream under CC BY 4.0.