Skip to the page

Data / Federal rules / 2025-09989

Schedules of Controlled Substances: Placement of 2-Methyl AP-237 in Schedule I; Correction

The Drug Enforcement Administration published this final rule in the Federal Register on June 3, 2025. It took effect on June 3, 2025.

SpecStream is the live web data engine for teams and agents. It reads every rule and proposed rule in the Federal Register each morning, and this page is that reading. Name your industry once and new rules, comment deadlines and effective dates arrive in your sheet, CRM, Slack or agent as they are published.

What the agency says

On March 15, 2024, the Drug Enforcement Administration published a final order placing 1-(2-methyl-4-(3-phenylprop-2-en-1- yl)piperazin-1-yl)butan-1-one (commonly known as 2-methyl AP-237), including its optical and geometric isomers, esters, ethers, salts, and salts of isomers, esters, and ethers whenever the existence of such isomers, esters, ethers, and salts is possible within the specific chemical designation, in schedule I of the Controlled Substances Act. The effective date of that final order was 30 days after publication in the Federal Register. Before the effective date, DEA published another final order that made the instructions for 2-methyl AP-237 in the March 15 final order invalid. This document corrects that error, adding 2- methyl AP-237 and its drug code 9664 for regulatory purposes.

Key facts

Document number
2025-09989
Type
Final rule
Action
Correcting amendment
Agency
Justice Department; Drug Enforcement Administration
Published
June 3, 2025
Takes effect
June 3, 2025
Dates
This correcting amendment is effective June 3, 2025, and applicable beginning April 15, 2024.
Docket
Docket No. DEA-1245
Code of Federal Regulations
21 CFR 1308
Topics
Administrative practice and procedure; Drug traffic control; Reporting and recordkeeping requirements
Pages
2

The document on federalregister.gov PDF

Other documents from the Drug Enforcement Administration

Everything from the Drug Enforcement Administration · Rules on administrative practice and procedure · Rules on drug traffic control · Rules on reporting and recordkeeping requirements · Published in June 2025

Read from the Federal Register API, last updated 2026-10-23. The document on federalregister.gov is the official record; dates and dockets can change through later corrections. Free to reuse with credit to SpecStream under CC BY 4.0.