Skip to the page

Data / Federal rules / 2025-22540

Schedules of Controlled Substances: Extension of Temporary Placement of MDMB-4en-PINACA in Schedule I of the Controlled Substances Act

The Drug Enforcement Administration published this final rule in the Federal Register on December 11, 2025. It took effect on December 12, 2025.

SpecStream is the live web data engine for teams and agents. It reads every rule and proposed rule in the Federal Register each morning, and this page is that reading. Name your industry once and new rules, comment deadlines and effective dates arrive in your sheet, CRM, Slack or agent as they are published.

What the agency says

The Administrator of the Drug Enforcement Administration is issuing this temporary scheduling order to extend the temporary schedule I status of MDMB-4en-PINACA. The schedule I status of MDMB- 4en-PINACA is in effect through December 12, 2025. This temporary order will extend the temporary scheduling of MDMB-4en-PINACA for one year, or until the permanent scheduling action for this substance is completed, whichever occurs first. As a result of this order, the regulatory controls and administrative, civil, and criminal sanctions applicable to schedule I controlled substances will continue to be imposed on persons who handle (manufacture, distribute, reverse distribute, import, export, engage in research, conduct instructional activities or chemical analysis with, or possess) or propose to handle MDMB-4en-PINACA.

Key facts

Document number
2025-22540
Type
Final rule
Action
Temporary scheduling order; extension
Agency
Justice Department; Drug Enforcement Administration
Published
December 11, 2025
Takes effect
December 12, 2025
Dates
This temporary scheduling order, which extends schedule I control of MDMB-4en-PINACA covered by an order (88 FR 86040, December 12, 2023), is effective December 12, 2025, and expires on December 12, 2026. If DEA publishes a final rule making this scheduling action permanent, this order will expire on the effective date of that rule, if the effective date is earlier than December 12, 2026.
Docket
Docket No. DEA-1356
Code of Federal Regulations
21 CFR 1308
Pages
3

The document on federalregister.gov PDF

Other documents from the Drug Enforcement Administration

Everything from the Drug Enforcement Administration · Published in December 2025

Read from the Federal Register API, last updated 2026-10-23. The document on federalregister.gov is the official record; dates and dockets can change through later corrections. Free to reuse with credit to SpecStream under CC BY 4.0.