Data / Federal rules / 2025-18431
Procedures for Chemical Risk Evaluation Under the Toxic Substances Control Act (TSCA)
The Environmental Protection Agency published this proposed rule in the Federal Register on September 23, 2025. Comments closed on November 7, 2025.
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What the agency says
The U.S. Environmental Protection Agency (EPA, "the Agency") is proposing to amend the procedural framework rule for conducting existing chemical risk evaluations under the Toxic Substances Control Act (TSCA). When conducting an existing chemical risk evaluation under TSCA, EPA must determine whether a chemical substance presents an unreasonable risk of injury to health or the environment, without consideration of costs or non-risk factors, including unreasonable risk to a potentially exposed or susceptible subpopulation identified as relevant to the risk evaluation, under the conditions of use. In this action, EPA proposes to rescind or revise certain 2024 amendments to the procedural framework rule to effectuate the best reading of the statute and ensure that the procedural framework rule does not impede the timely completion of risk evaluations or impair the effective and efficient protection of health and the environment.
Key facts
- Document number
- 2025-18431
- Type
- Proposed rule
- Action
- Proposed rule
- Agency
- Environmental Protection Agency
- Published
- September 23, 2025
- Comments due
- November 7, 2025
- Dates
- Comments must be received on or before November 7, 2025. Under the Paperwork Reduction Act, comments on the information collection provisions are best assured of consideration if the Office of Management and Budget (OMB) receives a copy of your comments on or before October 23, 2025.
- Docket
- EPA-HQ-OPPT-2025-0260; FRL-8529.1-01-OCSPP
- Regulation ID (RIN)
- 2070-AL27
- Code of Federal Regulations
- 40 CFR 702
- Topics
- Chemicals; Environmental protection; Hazardous substances
- Significant
- Yes, under Executive Order 12866
- Pages
- 28
Other documents from the Environmental Protection Agency
Everything from the Environmental Protection Agency · Rules on chemicals · Rules on environmental protection · Rules on hazardous substances · Published in September 2025
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