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Data / Store locations / The Home Depot / South Carolina

The Home Depot locations in South Carolina: 26 stores, with addresses and phone numbers

The Home Depot has 26 locations in South Carolina, 1.3% of its 2,028 in the United States, in 20 cities. The most are in Columbia, with 3. Each row links to the brand's own store locator, as read on October 24, 2026.

SpecStream is the live web data engine for teams and agents. It reads brand store locators and keeps every location with its address, phone and opening hours. Ask for the brands you track by state or category, and new openings and closures arrive in your sheet, CRM, Slack or agent as the brands publish them.

  • 26Locations
  • 20Cities
  • 1.3%Share of the brand
  • October 24, 2026Run date

The Home Depot locations in South Carolina

All 26 locations, ordered by city.

AddressCityZIPPhoneOpening hoursSource
1785 Whiskey RdAiken29803(803) 648-6291Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
3427 Clemson BlvdAnderson29621(864) 964-0820Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
20 Gateway Village RoadBluffton29910(843) 815-7000Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
2008 Magwood DrCharleston29414(843) 556-2447Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
7554 Northwood BlvdCharleston29406(843) 569-3773Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
285 Forum DriveColumbia29229(803) 419-9336Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
5200 Fernandina RdColumbia29212(803) 781-0877Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
7701 Two Notch RdColumbia29223(803) 736-1666Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
6607 Calhoun Memorial HwyEasley29640(864) 306-0137Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
3051 West Radio DriveFlorence29501(843) 661-2597Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
1339 S Pleasantburg DrGreenville29605(864) 236-0197Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
2490 N Pleasantburg DrGreenville29609(864) 232-0510Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
79 Woodruff Industrial LnGreenville29607(864) 284-0991Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
1385 W Wade Hampton BlvdGreer29650(864) 848-6083Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
1116 Highway 9 Byp WLancaster29720(803) 286-9700Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
5600 Sunset BlvdLexington29072(803) 359-1194Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
2213 North Highway 17Mount Pleasant29466(843) 972-6800Mo-Sa 06:00-21:00; Su 08:00-20:00homedepot.com
12262 Hwy 17 BypassMurrells Inlet29576(843) 357-3777Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
951 Oak Forest LnMyrtle Beach29577(843) 916-2229Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
620 Hwy 17 NNorth Myrtle Beach29582(843) 280-9908Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
2815 Home Depot BlvdRock Hill29730(803) 909-2420Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
1614 Sandifer BlvdSeneca29678(864) 886-0633Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
669 Fairview RoadSimpsonville29680(864) 963-7732Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
121 Dorman Center DriveSpartanburg29301(864) 574-2922Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
2300 E Main StreetSpartanburg29307(864) 579-0382Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com
190 Marymeade DrSummerville29483(843) 851-0468Mo-Sa 06:00-22:00; Su 08:00-20:00homedepot.com

Cities

CityLocations
Columbia3
Greenville3
Charleston2
Spartanburg2
Aiken1
Anderson1
Bluffton1
Easley1
Florence1
Greer1
Lancaster1
Lexington1
Mount Pleasant1
Murrells Inlet1
Myrtle Beach1
North Myrtle Beach1
Rock Hill1
Seneca1
Simpsonville1
Summerville1

Also on SpecStream

Updated November 7, 2026. Read from All the Places. All the Places data is CC0-1.0, a public domain dedication. Each location is read from the brand's own store locator by the All the Places project, which runs about once a week, so a location can have opened or closed since the run date. A brand is keyed on its Wikidata item when the project gives one, else on the project's own name for that brand's locator; two brands are never merged on a name. A repeated address of one brand counts once. Locations named for a private person are left out. Opening hours are shown as the brand lists them. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.