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Data / Research funding / Tuberculosis Vaccine

Tuberculosis Vaccine: 127 NIH awards ($584.7M) to 59 organizations

127 NIH awards ($584.7M) in the NIH spending category Tuberculosis Vaccine, to 59 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

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Awards

127 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
HIV Vaccines Clinical Trials Network Leadership and Operations CenterNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$244,071,463June 29, 2006November 30, 2027COREY, LAWRENCEreporter.nih.gov
Immune Mechanisms of Protection Against Mycobacterium Tuberculosis Center (IMPAC-TB)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$61,029,344September 30, 2019March 31, 2027URDAHL, KEVINreporter.nih.gov
Immune Mechanisms of Protection Against Mycobacterium Tuberculosis Center (IMPAC-TB)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$38,435,039September 30, 2019September 29, 2026FORTUNE, SARAHreporter.nih.gov
Immune Mechanisms of Protection Against Mycobacterium Tuberculosis Center (IMPAC-TB)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$35,184,139August 1, 2021July 31, 2026COLER, RHEAreporter.nih.gov
Vaccine and Treatment Evaluation Unit at Saint Louis UniversityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$21,219,564December 11, 2019November 30, 2026HOFT, DANIEL F.reporter.nih.gov
Development of an Optimized Adjuvanted TB VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$11,645,061September 30, 2021September 30, 2025EVANS, JAYreporter.nih.gov
Advancing Vaccine Adjuvant Research for Tuberculosis (TB)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$10,964,476September 30, 2022September 29, 2027BRITTON, WARWICKreporter.nih.gov
DEVELOPMENT OF UM-1098: A NOVEL SYNTHETIC TH17 INDUCING ADJUVANT AND DELIVERY SYSTEMNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$9,566,206September 30, 2023September 29, 2026EVANS, JAYreporter.nih.gov
Harnessing B cells for TB vaccine development to improve therapy of TB and TB-HIV coinfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,398,428July 1, 2021June 30, 2027GENGENBACHER, MARTIN ALFONSreporter.nih.gov
Preventing TB with intravenous BCG in SIV-infected macaquesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,248,442May 5, 2021April 30, 2026SCANGA, CHARLES A.reporter.nih.gov
The Role of Lipid-specific T cells in Mediating Protection Against M. tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,208,331June 1, 2020July 31, 2030SESHADRI, CHETANreporter.nih.gov
Role of Inducible Bronchus Associated Lymphoid Tissue in Latent TuberculosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$4,152,012February 1, 2023January 31, 2027KHADER, SHABAANA A.reporter.nih.gov
A STINGing vaccine for TBNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,090,805June 1, 2020May 31, 2026BISHAI, WILLIAM RAMSESreporter.nih.gov
Development of a novel TB vaccine safer and more effective than BCG based on a precisely controlled replication-limited Mycobacterium tuberculosis engineered for optimal in vivo growth and clearanceNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,876,556March 15, 2021February 28, 2027HORWITZ, MARCUS AARONreporter.nih.gov
Discovery of Adjuvants that Direct T-cell Fates for Improved Safety and Efficacy in Vaccines Against Influenza and TuberculosisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,714,524September 30, 2025September 29, 2026ESSER-KAHN, AARONreporter.nih.gov
Identification of Novel Syk/Raf-1 Mediated CLR Ligands as Vaccine AdjuvantsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,198,798September 30, 2025September 29, 2026EVANS, JAYreporter.nih.gov
Enhancing cytotoxic lymphocytes in a TB vaccine strategyNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,037,076February 25, 2022January 31, 2027FLYNN, JOANNE L.reporter.nih.gov
Therapeutic vaccination to augment stringent response-specific T-cell immunity to MTB persistersNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,027,518March 17, 2020February 28, 2025KARAKOUSIS, PETROS Creporter.nih.gov
Mechanisms of CD4 T cell help to myeloid cells in tuberculosisNIHNational Institute of Allergy and Infectious Diseases2025$2,863,501August 1, 2025July 31, 2029BOLD, TYLER DALLASreporter.nih.gov
Adjuvant Development in the context of a vaccine to protect against tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,722,493September 30, 2018September 29, 2023PETROVSKY, NIKOLAIreporter.nih.gov
Regulation of innate immunity by self-adjuvated MRNA vaccinesNIHNational Institute of Allergy and Infectious Diseases2025$2,710,680August 12, 2025May 31, 2029JAGANNATH, CHINNASWAMYreporter.nih.gov
Th9 cells and protective TB immunityNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,670,376March 9, 2022February 28, 2027HOFT, DANIEL F.reporter.nih.gov
Lung immune function in human TB infection and its perturbation by HIV-1.NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,627,712June 4, 2020May 31, 2025RUSSELL, DAVID Greporter.nih.gov
Functionally distinct human CD4 T cell responses to novel evolutionarily selected M. tuberculosis antigensNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,540,587July 1, 2023June 30, 2028ERNST, JOEL D.reporter.nih.gov
Optimization and Advanced Proof-of-Concept Studies of a Listeria-vectored Multi-Antigenic Vaccine against TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,406,319December 1, 2017November 30, 2025HORWITZ, MARCUS AARONreporter.nih.gov
Defining the Immunogenicity and Efficacy of a Durable BCG Vaccine Strategy Optimized for Preventing TB in Pediatric HIV InfectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,404,290July 20, 2023June 30, 2028SCANGA, CHARLES A.reporter.nih.gov
Development of a Self Inactivating, Highly Effective TB VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,381,016February 6, 2019January 31, 2024FLYNN, JOANNE L.reporter.nih.gov
Molecular Genetic Analysis of Mycobacterium TuberculosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,368,749December 1, 1988August 31, 2028JACOBS, WILLIAM ROBERTreporter.nih.gov
Characteristics and protective efficacy of human antibodies against M. tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,338,122July 1, 2019June 30, 2025ACHKAR, JACQUELINE MICHELEreporter.nih.gov
Mechanisms of efficient control of Mycobacterium tuberculosis in the lungs prior to granulomaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,322,288July 9, 2024May 31, 2029KAUSHAL, DEEPAKreporter.nih.gov
Durability of systemic and lung immune correlates of BCG-induced protection against M. tuberculosis infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,311,437August 11, 2020July 31, 2026NEMES, ELISAreporter.nih.gov
Role of IL-17 in Protective Vaccine-induced Immune Responses Against TuberculosisNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,302,219December 15, 2010July 31, 2026KHADER, SHABAANA A.reporter.nih.gov
Optimization and preclinical development of a TB Multiple Antigen Presenting System (MAPS) vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,298,018December 15, 2017November 30, 2023MALLEY, RICHARDreporter.nih.gov
Mechanisms of vitamin A-dependent risk for tuberculosis progression and preventionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,246,313June 15, 2023May 31, 2028PODELL, BRENDANreporter.nih.gov
Defining the antibody interface between Mycobacterium tuberculosis and host immunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,063,021September 23, 2021August 31, 2027LU, LENETTEreporter.nih.gov
Immunotherapeutic approach for the prevention of secondary infection with drug-resistant TBNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,956,687June 13, 2024April 30, 2029COLER, RHEA Nreporter.nih.gov
A dual function TB subunit vaccine designed for non-interference with BCG and post-exposure activityNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,803,446December 1, 2017November 30, 2023MORTENSEN, RASMUS SKAARUPreporter.nih.gov
Targeting trained immunity and Th1/Th17 axis with combination adjuvantsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,799,999July 26, 2021April 30, 2027KHADER, SHABAANA A.reporter.nih.gov
Multivalent DNA vaccine-mediated protection against TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,773,692November 23, 2017October 31, 2024WEINER, DAVID B.reporter.nih.gov
Harnessing activated CD4 T cells to define new mechanisms of protection in tuberculosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,770,744July 1, 2023June 30, 2028BOLD, TYLER DALLASreporter.nih.gov
Optimizing vaccine science to improve the outcome of tuberculosis treatmentNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,751,227June 17, 2021May 31, 2027SUBBIAN, SELVAKUMARreporter.nih.gov
SigH based attenuated, efficacious Mtb vaccines to protect against lethal TBNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,745,052May 17, 2018April 30, 2025KAUSHAL, DEEPAKreporter.nih.gov
A Novel Th17-inducing Mucosal Vaccine for TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,676,215September 9, 2020September 2, 2022KHADER, SHABAANA A.reporter.nih.gov
RNA Vaccine Innovations for TB: Targeting the MucosaNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,632,094April 22, 2022September 30, 2025REED, STEVEN GREGORYreporter.nih.gov
Advancing Innovative Next_generation Heterologous Vaccines Against TuberculosisNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,615,572May 10, 2022April 30, 2026BEAMER, GILLIAN Lreporter.nih.gov
Mechanisms of IFNg-independent T cell and B cell-mediated protection in TB.NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,569,789August 26, 2024June 30, 2029SALGAME, PADMINIreporter.nih.gov
Understanding early macrophage-T cell interactions, SLAMF1, and immunity to TBNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,544,840July 1, 2024June 30, 2029PHILIPS, JENNIFER Areporter.nih.gov
Design and characterization of biomimetic nanobiomaterials to elicit CD1-restricted T cell responses during sub-unit vaccinationNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,522,818August 1, 2019July 31, 2025SCOTT, EVAN ALEXANDERreporter.nih.gov
Ontogeny and metabolism of lung alveolar macrophages in tuberculosisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,503,349August 13, 2024July 31, 2029HUANG, LUreporter.nih.gov
Ultrasensitive detection of Mycobacterium tuberculosis infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,461,934July 22, 2024June 30, 2029CIRILLO, JEFFREY D.reporter.nih.gov
Novel Nanoparticle Respiratory Tract Mucosal VaccineNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,426,482April 1, 2022March 31, 2025QUINN, FREDERICK Dreporter.nih.gov
Optimizing vaccine science to improve the outcome of tuberculosis treatmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,409,583June 17, 2021May 31, 2023SUBBIAN, SELVAKUMARreporter.nih.gov
Regulation of CD8+ T cell immunity to tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,409,160August 2, 2013April 30, 2024BEHAR, SAMUEL Mreporter.nih.gov
Developing a Multivalent Subunit Particle Vaccine Against TuberculosisNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,392,562April 1, 2022March 31, 2025LOVELL, JONATHAN Freporter.nih.gov
A novel hyper-immunogenic low virulent BCG vaccine against tuberculosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,373,187February 3, 2023April 20, 2025DHANDAYUTHAPANI, SUBRAMANIANreporter.nih.gov
Development of Novel mRNA Vaccines Against Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,336,253May 20, 2022March 31, 2025POSTLER, THOMAS SIEGMUNDreporter.nih.gov
BCG overexpressing a small molecule STING agonist as a vaccine for TBNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,261,288June 20, 2024July 31, 2028WALLACH, TODDreporter.nih.gov
The role of non-classical MHC class I molecules in immune responses to Mycobacterium tuberculosis infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,184,815May 14, 2018April 30, 2025WANG, CHYUNG-RUreporter.nih.gov
Targeting trained immunity and Th1/Th17 axis with combination adjuvantsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,167,749July 26, 2021September 1, 2022KHADER, SHABAANA A.reporter.nih.gov
Oral BCG: Optimizing mucosal vaccination against tuberculosisNIHNational Institute of Allergy and Infectious Diseases2025$1,162,224April 24, 2025March 31, 2030LIN, PHILANA LINGreporter.nih.gov
Memory, Phenotype, and Function of TB-reactive Human MR1 Restricted T cellsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,133,140February 1, 2019January 31, 2024LEWINSOHN, DAVID M.reporter.nih.gov
Immunoregulation by indoleamine 2,3-dioxygenases in tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,083,318May 1, 2018April 30, 2024CHAN, JOHN R.reporter.nih.gov
Development of a novel adjuvanted Th1- and Th17-inducing subunit TB VaccineNIHNational Institute of Allergy and Infectious Diseases2025$1,067,980March 1, 2023August 31, 2027KHADER, SHABAANA A.reporter.nih.gov
Determinants of antigen specific CD4 T cell function in tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,006,392April 1, 2021September 30, 2026BOLD, TYLER DALLASreporter.nih.gov
TOLLIP Deficiency, Immune Dysregulation, and Tuberculosis SusceptibilityNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,003,164March 1, 2018February 29, 2024SHAH, JAVEED ALIreporter.nih.gov
Live nasal recombinant B. pertussis vaccine against tuberculosisNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$972,074May 4, 2022March 31, 2026GOLDSTEIN, PETERreporter.nih.gov
Developing a Multivalent Subunit Particle Vaccine Against TuberculosisNIHNational Institute of Allergy and Infectious Diseases2025$955,150April 1, 2022May 31, 2027LOVELL, JONATHAN Freporter.nih.gov
Development of a novel adjuvanted Th1- and Th17-inducing subunit TB VaccineNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$952,443March 1, 2023February 28, 2026KHADER, SHABAANA A.reporter.nih.gov
Influence of SIV replication on TB progression and immunityNIHNational Institute of Allergy and Infectious Diseases2021$945,816June 26, 2017May 31, 2023AMBROSE, ZANDREAreporter.nih.gov
The Role of Group 3 Innate Lymphoid cells (ILC3) in TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021$915,731May 22, 2020September 30, 2022KHADER, SHABAANA A.reporter.nih.gov
A Novel Th17-inducing Mucosal Vaccine for TuberculosisNIHNational Institute of Allergy and Infectious Diseases2023$914,044September 9, 2020August 31, 2025KHADER, SHABAANA A.reporter.nih.gov
Evaluating the safety, immunogenicity and efficacy of a robust attenuated Mtb vaccine in the setting of HIV co-infectionNIHNational Institute of Allergy and Infectious Diseases2025$905,998June 17, 2025May 31, 2030KAUSHAL, DEEPAKreporter.nih.gov
A Neonatal Monkey Model of Tuberculosis VaccinationNIHNational Institute of Allergy and Infectious Diseases2021$893,080June 1, 2019May 31, 2023JAGANNATH, CHINNASWAMYreporter.nih.gov
Immune Correlates of Protection from TBNIHNational Institute of Allergy and Infectious Diseases2022$889,259July 1, 2017June 30, 2024KAUSHAL, DEEPAKreporter.nih.gov
PROTECTIVE CD8 T CELL RESPONSES to TUBERCULOSISNIHNational Institute of Allergy and Infectious Diseases2025$832,076August 8, 2025July 31, 2030BEHAR, SAMUEL Mreporter.nih.gov
Evaluating human T cells specific for Mycobacterium tuberculosis antigens that are processed and presented by infected macrophagesNIHNational Institute of Allergy and Infectious Diseases2025$813,450August 1, 2025July 31, 2030CARPENTER, STEPHEN MATTHEWreporter.nih.gov
Determining Protective Features of Human Memory T-cells to Inform Mycobacterium tuberculosis Vaccine DevelopmentNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$773,280August 11, 2022July 31, 2027CARPENTER, STEPHEN MATTHEWreporter.nih.gov
Novel Nanoparticle Respiratory Tract Mucosal VaccineNIHNational Institute of Allergy and Infectious Diseases2025$763,709April 1, 2022July 31, 2027QUINN, FREDERICK Dreporter.nih.gov
Molecular basis of BCG vaccine sub-strain heterogeneityNIHNational Institute of Allergy and Infectious Diseases2025$749,192November 22, 2024October 31, 2029CIRILLO, JEFFREY D.reporter.nih.gov
HLA-E restricted T-cell immunity in Mycobacterium tuberculosis infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$734,192September 4, 2019August 31, 2024JOOSTEN, SIMONE ANNEreporter.nih.gov
Development of Novel mRNA Vaccines Against Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2025$700,469May 20, 2022May 31, 2027POSTLER, THOMAS SIEGMUNDreporter.nih.gov
Dissecting the role of vaccine-promoted Th17 cells in protective immunity against tuberculosisNIHNational Institute of Allergy and Infectious Diseases2025$666,567August 19, 2025July 31, 2030MORTENSEN, RASMUS SKAARUPreporter.nih.gov
Eliciting lung-localized CD4 T cell responses against Mycobacterium tuberculosis in preventive and post-exposure settingsNIHNational Institute of Allergy and Infectious Diseases2021$660,785August 22, 2017July 31, 2023URDAHL, KEVIN Breporter.nih.gov
Innate-adaptive crosstalk in protective and vaccine-induced immunity to TBNIHNational Institute of Allergy and Infectious Diseases2021$648,004June 20, 2017May 31, 2022RENGARAJAN, JYOTHIreporter.nih.gov
A novel quadruple knockout MTb vaccine against tuberculosis (Supplement Resubmission)NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$626,202June 8, 2021May 31, 2025DHANDAYUTHAPANI, SUBRAMANIANreporter.nih.gov
Estimating the Epidemiologic Impact of TB Vaccines using Mathematical ModelsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$599,924August 18, 2022July 31, 2027NELSON, KRISTIN NICOLE BRATTONreporter.nih.gov
Therapeutic vaccine platform to boost immune responses in TuberculosisNIHNational Institute of Allergy and Infectious Diseases2025$599,471August 1, 2025July 31, 2027ANTHONY, KAREN G.reporter.nih.gov
Immunometabolic signatures of BCG-induced neonatal trained immunityNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$528,634July 6, 2023June 30, 2028ANGELIDOU, ASIMENIAreporter.nih.gov
Immunoregulation by indoleamine 2,3-dioxygenases in tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021$506,563May 1, 2018September 15, 2021CHAN, JOHN R.reporter.nih.gov
Conditionally replicating Mycobacterium tuberculosis vaccinesNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$479,204September 1, 2018August 31, 2024EHRT, SABINEreporter.nih.gov
Development of a novel adjuvanted Th1- and Th17-inducing subunit TB VaccineNIHNational Institute of Allergy and Infectious Diseases2022$467,889March 1, 2022September 1, 2022KHADER, SHABAANA A.reporter.nih.gov
The impact of IL-4 and IL-4-producing cells on protective immunity to tuberculosisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$464,662December 8, 2023October 31, 2025BEHAR, SAMUEL Mreporter.nih.gov
The impact of mucociliary clearance on Mycobacterium tuberculosis pathogenesisNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$456,550March 21, 2023February 28, 2026SHAH, JAVEED ALIreporter.nih.gov
High-Throughput TB Vaccine Antigen DiscoveryNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$454,497June 1, 2019August 31, 2024MARTINOT, AMANDAreporter.nih.gov
A novel c-di-AMP-based recombinant BCG vaccineNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$448,250February 9, 2023January 31, 2026BAI, GUANGCHUNreporter.nih.gov
The human lung and lung-draining lymph node response to Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$433,592January 12, 2023December 31, 2024ROY CHOWDHURY, ROSHNIreporter.nih.gov
Epigenetic Study of Resistance to Infection by Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$430,188June 8, 2021May 31, 2025SUN, YANreporter.nih.gov
Novel multivalent viral vectored tuberculosis vaccines targeting lung immunityNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$416,946June 23, 2023May 31, 2025TISCHLER, ANNA DEGRAFFreporter.nih.gov
Mechanisms of a therapeutic DNA vaccine targeting Mycobacterium tuberculosis persistersNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$401,760December 11, 2023November 30, 2028KARANIKA, STYLIANIreporter.nih.gov
Mycobacterial determinants of escape from pathogen-specific immunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$397,440June 14, 2018May 31, 2023CAREY, ALLISONreporter.nih.gov
Live Imaging of Immunity to M. tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$390,866January 6, 2021December 31, 2023ERNST, JOEL D.reporter.nih.gov
A novel approach to determine the value of ESAT-6 as an antigen in M. tuberculosis infection and vaccinesNIHNational Institute of Allergy and Infectious Diseases2025$278,390February 1, 2025January 31, 2027ERNST, JOEL D.reporter.nih.gov
Effect of Community Wide Deworming on Hookworm Modulated Immune Responses to Bystander Antigens and Vaccines in Southern IndiaNIHFogarty International Center2021 to 2024$276,148February 28, 2020January 31, 2025AJJAMPUR, SITARA SWARNA RAOreporter.nih.gov
A whole-cell inactivated vaccine for improved protection against tuberculosisNIHNational Institute of Allergy and Infectious Diseases2025$269,874August 1, 2025July 31, 2027ARTINGER, MICHAELreporter.nih.gov
Non-tuberculous mycobacterium and B cells in the stimulation of ectopic germinal centers and immunological control of pulmonary tuberculosisNIHNational Institute of Allergy and Infectious Diseases2025$249,000August 1, 2023August 31, 2027DUTT, TARU S.reporter.nih.gov
Acellular TB vaccines adjuvanted with BcfANIHNational Institute of Allergy and Infectious Diseases2021$234,000March 5, 2020February 28, 2023DUBEY, PURNIMAreporter.nih.gov
Non-tuberculous mycobacterium and B cells in the stimulation of ectopic germinal centers and immunological control of pulmonary tuberculosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$224,722August 1, 2023July 31, 2025DUTT, TARU S.reporter.nih.gov
Early T cell responses in tuberculosisNIHNational Institute of Allergy and Infectious Diseases2025$209,408September 19, 2025August 31, 2030SIMONSON, ANDREW WILLIAMreporter.nih.gov
The Role of SLAMF1 in TB ImmunityNIHNational Institute of Allergy and Infectious Diseases2021$196,875June 1, 2020May 31, 2023PHILIPS, JENNIFER Areporter.nih.gov
Role of molecular drivers in memory group 1 CD1-restricted T cell differentiation and Mycobacterium tuberculosis infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$195,960September 15, 2021August 31, 2025MORGUN, EVAreporter.nih.gov
Cross development of surrogate efficacy mycobacterial growth inhibition assay endpoint for the translational guinea pig modelNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$195,700May 16, 2024March 31, 2026COLER, RHEA Nreporter.nih.gov
Mucosal Adjuvant to Induce Multipronged T Cell Immunity to TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021$194,167March 12, 2020August 31, 2022SURESH, MARULASIDDAPPAreporter.nih.gov
Interferon gamma-dependent immunity to Mycobacterium tuberculosis mediated by regulation of inflammation by lung macrophagesNIHNational Institute of Allergy and Infectious Diseases2025$188,760September 1, 2025August 31, 2030MACIAG, KAROLINAreporter.nih.gov
Host genetic diversity, T cell responses, and outcomes of TBNIHNational Institute of Allergy and Infectious Diseases2021$181,165September 1, 2020August 31, 2023ERNST, JOEL D.reporter.nih.gov
Host genetic diversity, mononuclear phagocytes, and outcomes of TBNIHNational Institute of Allergy and Infectious Diseases2021$161,500June 16, 2020May 30, 2022ERNST, JOEL D.reporter.nih.gov
Mechanistic investigation of differential T cell responses to distinct Mycobacterium tuberculosis antigensNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$131,910July 1, 2022June 30, 2025HOWARD, ZACHARYreporter.nih.gov
The role of antigen-independent T cell activation in controlling M. tuberculosis infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$98,512February 1, 2024January 31, 2027WINTER, CASSANDRAreporter.nih.gov
Investigating the role of gamma delta (γδ) T cells in the control of Mycobacterium tuberculosis infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$98,512August 1, 2024July 31, 2027TAPPEN, VICTORIAreporter.nih.gov
Development of Small Molecule Probes for the Selective Modification and Labeling of the Mycobacterial Cell WallNIHNational Institute of General Medical Sciences2021 to 2022$85,245April 6, 2021June 30, 2022KIM, DARIA ELDAROVNAreporter.nih.gov
Impact of Mycobacterium tuberculosis on monocyte differentiation in vivoNIHNational Heart, Lung, and Blood Institute2023$80,928February 1, 2023January 31, 2024MOHAPATRA, ALEXANDERreporter.nih.gov
The impact of two-pore channel calcium signaling on MR1 antigen presentation of Mycobacterium tuberculosis metabolitesNIHNational Institute of Allergy and Infectious Diseases2025$49,538September 1, 2025August 31, 2027TAMMEN, ALLISONreporter.nih.gov
Elucidating the mechanism and correlates of protection elicited by CDN adjuvanted vaccines for M. tuberculosis.NIHNational Institute of Allergy and Infectious Diseases2025$48,395November 1, 2025June 30, 2027LAMB-ECHEGARAY, ISABELreporter.nih.gov
Cytomegalovirus as a risk factor for exacerbation of Mycobacterium tuberculosis infectionNIHNational Institute of Allergy and Infectious Diseases2021$39,793April 1, 2020April 2, 2021IZZO, ANGELO Areporter.nih.gov
Exploiting Fc-engineering to dissect mechanisms of anti-microbial action of M. tuberculosis-specific antibodiesNIHNational Institute of Allergy and Infectious Diseases2021$32,020September 1, 2020July 5, 2022IRVINE, EDWARD BUFORDreporter.nih.gov
Infectious Diseases in Africa: Correlates of Protection, Lessons from Vaccines and Natural Infection StudiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$25,001March 3, 2020February 28, 2023FERRARI, GUIDOreporter.nih.gov
6th Global Forum on TB VaccinesNIHNational Institute of Allergy and Infectious Diseases2021$6,500April 16, 2021March 31, 2022FREVOL, AUDEreporter.nih.gov
Tuberculosis: Heterogeneity from Experimental Models to Human DiseaseNIHNational Institute of Allergy and Infectious Diseases2025$6,500January 23, 2025December 31, 2025SHEPPARD, TERRY L.reporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Fred Hutchinson Cancer CenterSeattle, WA1$244.1 million0$0
Seattle Children's HospitalSeattle, WA5$99 million0$0
Harvard University D/b/a Harvard School of Public HealthBoston, MA2$38.5 million0$0
University of MontanaMissoula, MT3$24.4 million0$0
Saint Louis UniversitySaint Louis, MO2$23.9 million0$0
University of ChicagoChicago, IL8$15.3 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA7$14.4 million0$0
University of SydneySydney1$11 million0$0
Johns Hopkins UniversityBaltimore, MD3$7.5 million0$0
Texas Biomedical Research InstituteSan Antonio, TX5$7.5 million0$0
Hackensack University Medical CenterHackensack, NJ1$6.4 million0$0
University of California Los AngelesLos Angeles, CA2$6.3 million0$0
University of MinnesotaMinneapolis, MN4$6.1 million0$0
University of WashingtonSeattle, WA6$6.1 million0$0
Washington UniversitySaint Louis, MO6$6 million0$0
Albert Einstein College of MedicineBronx, NY3$5.2 million0$0
University of California, San FranciscoSan Francisco, CA7$3.8 million0$0
Methodist Hospital Research InstituteHouston, TX2$3.6 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ2$3.3 million0$0
Vaxine Pty LTDBedford Park1$2.7 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA3$2.7 million0$0
Cornell UniversityIthaca, NY1$2.6 million0$0
Colorado State UniversityFort Collins, CO3$2.5 million0$0
Rbhs-New Jersey Medical SchoolNewark, NJ2$2.5 million0$0
Statens Serum InstituteCopenhagen2$2.5 million0$0
SUNY at BuffaloAmherst, NY2$2.3 million0$0
University of Cape TownRondebosch1$2.3 million0$0
Boston Children's HospitalBoston, MA1$2.3 million0$0
Texas A&m University Health Science CTRCollege Station, TX2$2.2 million0$0
University of Georgia Research Foundation IncAthens, GA2$2.2 million0$0
Ut Southwestern Medical CenterDallas, TX1$2.1 million0$0
International Aids Vaccine InitiativeNew York, NY3$2 million0$0
Texas Tech University Health Sciences Center at El PasoEl Paso, TX2$2 million0$0
Wistar InstitutePhiladelphia, PA1$1.8 million0$0
Emory UniversityAtlanta, GA3$1.7 million0$0
HDT Bio CorporationSeattle, WA1$1.6 million0$0
Case Western Reserve UniversityCleveland, OH2$1.6 million0$0
Northwestern UniversityChicago, IL1$1.5 million0$0
Univ of Arkansas for Med ScisLittle Rock, AR1$1.5 million0$0
Northwestern University at ChicagoChicago, IL2$1.4 million0$0
Oncosting LLCBaltimore, MD1$1.3 million0$0
Oregon Health & Science UniversityPortland, OR2$1.2 million0$0
Iliad Biotechnologies, LLCNew York, NY1$972,0740$0
Leiden University Medical CenterLeiden1$734,1920$0
L2 Diagnostics, LLCNew Haven, CT1$599,4710$0
Beth Israel Deaconess Medical CenterBoston, MA1$528,6340$0
Weill Medical Coll of Cornell UnivNew York, NY1$479,2040$0
Tufts University BostonBoston, MA1$454,4970$0
Albany Medical CollegeAlbany, NY1$448,2500$0
University of UtahSalt Lake City, UT1$397,4400$0
Christian Medical CollegeVellore1$276,1480$0
Solaris Vaccines, Inc.Fort Collins, CO1$269,8740$0
University of Alabama at BirminghamBirmingham, AL1$249,0000$0
Ohio State UniversityColumbus, OH1$234,0000$0
University of Wisconsin-MadisonMadison, WI1$194,1670$0
Massachusetts Institute of TechnologyCambridge, MA1$85,2450$0
University of California-BerkeleyBerkeley, CA1$48,3950$0
Duke UniversityDurham, NC1$25,0010$0
Keystone SymposiaSilverthorne, CO1$6,5000$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
202564$90,612,1340$0
202462$100,434,8350$0
202353$130,296,3670$0
202258$197,346,4460$0
202155$66,046,3760$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 1 award here
Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required)RFA-AI-27-002NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 113 awards here
Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)RFA-AI-27-005NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 113 awards here
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)PAR-25-370NIH93.855November 16, 2026$50,000Same assistance listing 93.855 as 113 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 113 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 113 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.855January 7, 2027Not listedSame assistance listing 93.855 as 113 awards here
HIV/AIDS Clinical Trials Network Leadership and Operations CentersRFA-AI-28-001NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 113 awards here
HIV/AIDS Clinical Trials Network Laboratory CentersRFA-AI-28-002NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 113 awards here
HIV/AIDS Clinical Trials Network Statistical and Data Management CentersRFA-AI-28-003NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 113 awards here
HIV/AIDS Clinical Trials Network Clinical Trials UnitsRFA-AI-28-004NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 113 awards here
Precision and Systems Biology to Uncover the Link Between Chronic and Infectious DiseasesRFA-AI-28-014NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 113 awards here
Immune Tolerance Network (UM1 Clinical Trial Required)RFA-AI-28-005NIH93.855January 29, 2027Not listedSame assistance listing 93.855 as 113 awards here
Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)RFA-AI-28-012NIH93.855January 29, 2027Not listedSame assistance listing 93.855 as 113 awards here
Accelerating Research and Development of Next Generation Vaccines against Malaria - a Model for Mosquito-Borne Diseases (R61/R33 Clinical Trial Not Allowed)RFA-AI-28-024NIH93.855February 11, 2027Not listedSame assistance listing 93.855 as 113 awards here
NLM Institutional Grants for Research Training in Biomedical Informatics, Data Science, and AI (T15 Independent Clinical Trial Not Allowed)RFA-LM-28-001NIH93.855February 11, 2027$775,000Same assistance listing 93.855 as 113 awards here
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)PA-27-100NIH93.855April 5, 2027Not listedSame assistance listing 93.855 as 113 awards here
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)PA-27-102NIH93.855April 5, 2027Not listedSame assistance listing 93.855 as 113 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIH93.855May 7, 2027Not listedSame assistance listing 93.855 as 113 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185NIH93.855May 7, 2027Not listedSame assistance listing 93.855 as 113 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.