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Data / Research funding / Tuberculosis

Tuberculosis: 1,132 NIH awards ($3.1B) to 245 organizations

1,132 NIH awards ($3.1B) in the NIH spending category Tuberculosis, to 245 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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NIH spending category

Awards

The 500 largest of 1,132 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other InfectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$472,070,715December 1, 2024November 30, 2025CURRIER, JUDITH S.reporter.nih.gov
HIV Vaccines Clinical Trials Network Leadership and Operations CenterNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$244,071,463June 29, 2006November 30, 2027COREY, LAWRENCEreporter.nih.gov
HIV Vaccine Trials Network Laboratory CenterNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$177,480,054June 29, 2006November 30, 2027MCELRATH, MARGARET JULIANAreporter.nih.gov
Statistical and Data Management Center (SDMC), Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (ACTG)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$84,840,845June 29, 2006November 30, 2027HUGHES, MICHAEL DAVIDreporter.nih.gov
IMPAACT Leadership GroupNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$77,468,129December 1, 2024November 30, 2027NACHMAN, SHARON Areporter.nih.gov
Immune Mechanisms of Protection Against Mycobacterium Tuberculosis Center (IMPAC-TB)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$61,029,344September 30, 2019March 31, 2027URDAHL, KEVINreporter.nih.gov
SDMC - IMPAACT Leadership GroupNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$59,233,299June 29, 2006November 30, 2027SHAPIRO, DAVID ERICreporter.nih.gov
AIDS Clinical Trial Group Laboratory CenterNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$56,714,107January 1, 2014November 30, 2027ALDROVANDI, GRACE Mreporter.nih.gov
Immune Mechanisms of Protection Against Mycobacterium Tuberculosis Center (IMPAC-TB)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$38,435,039September 30, 2019September 29, 2026FORTUNE, SARAHreporter.nih.gov
Immune Mechanisms of Protection Against Mycobacterium Tuberculosis Center (IMPAC-TB)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$35,184,139August 1, 2021July 31, 2026COLER, RHEAreporter.nih.gov
University of North Carolina Global HIV Prevention and Treatment Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$24,477,809February 1, 2007November 30, 2027ERON, JOSEPH Jreporter.nih.gov
UZ-UCSF CTUNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$21,624,239September 9, 2025November 30, 2027CHIRENJE, ZVAVAHERA MIKEreporter.nih.gov
UCLA AIDS Prevention and Treatment Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$21,546,764February 1, 2007November 30, 2027LANDOVITZ, RAPHAEL Jreporter.nih.gov
Vaccine and Treatment Evaluation Unit at Saint Louis UniversityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$21,219,564December 11, 2019November 30, 2026HOFT, DANIEL F.reporter.nih.gov
International Maternal, Adolescent and Pediatric Therapeutics Clinical Trials NetworkNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$20,605,531January 1, 2014November 30, 2027ALDROVANDI, GRACE Mreporter.nih.gov
UCSD Collaborative Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$18,116,542December 1, 2024November 30, 2027WILKIN, TIMOTHY J.reporter.nih.gov
East Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional ConsortiumNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$17,134,028June 1, 2025June 30, 2026WOOLS-KALOUSTIAN, KARA KAYreporter.nih.gov
Emory-CDC CTUNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$16,972,899December 1, 2024November 30, 2027KELLEY, COLLEEN Freporter.nih.gov
International epidemiology Databases to Evaluate AIDS (IeDEA) Southern Africa.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$16,840,939May 1, 2025April 30, 2027ROHNER, ELIANEreporter.nih.gov
Central Africa International Epidemiology databases to Evaluate AIDSNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$15,957,495May 1, 2025April 30, 2027YOTEBIENG, MARCELreporter.nih.gov
Transmission Aerobiology of M. tuberculosis: Genes and Metabolic Pathways That Sustain Mtb Across an Evolutionary BottleneckNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$15,828,159May 13, 2021April 30, 2027RHEE, KYU Yreporter.nih.gov
C3PO - The Candidate Clinical Correlate of Prognostic Outcome for TB StudyNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$15,575,398July 1, 2024May 31, 2026NAHID, PAYAMreporter.nih.gov
PERU Clinical Trial UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$15,506,525December 1, 2024November 30, 2027SANCHEZ, JORGE LUISreporter.nih.gov
Caribbean, Central, and South America network for HIV Epidemiology (CCASAnet)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$15,404,946May 1, 2025June 30, 2026CASTILHO, JESSICA Lreporter.nih.gov
PHRU-Setshaba Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$15,110,381December 1, 2024November 30, 2027GRAY, GLENDA Ereporter.nih.gov
Preclinical Design and Clinical Translation of TB Regimens (PReDicTR) ConsortiumNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$14,399,999March 26, 2024February 28, 2029SAVIC, RADOJKAreporter.nih.gov
HIV/AIDS Clinical Trials Units University of Cape Town CTU 2020 to 2027NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$13,518,599April 1, 2007November 30, 2027BEKKER, LINDA-GAILreporter.nih.gov
Metabolic determinants of Mtb virulence, vulnerability and variationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$13,485,680May 1, 2025April 30, 2027MOODY, DAVID BRANCHreporter.nih.gov
Vanderbilt HIV Clinical Trials Unit (CTU)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$12,733,650February 1, 2007November 30, 2027HAAS, DAVID Wreporter.nih.gov
Case Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$12,725,521December 1, 2024November 30, 2027YENDEWA, GEORGEreporter.nih.gov
Respiratory pathogen-specific T cell signatures following vaccination, natural infection, and treatmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$12,580,221June 1, 2025May 31, 2027SETTE, ALESSANDROreporter.nih.gov
Columbia Collaborative HIV/AIDS Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$12,286,513February 1, 2007November 30, 2027SOBIESZCZYK, MAGDALENA ELZBIETAreporter.nih.gov
TB-RICC 3.0NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$11,818,694April 1, 2023March 31, 2028ELLNER, JERROLD J.reporter.nih.gov
Development of an Optimized Adjuvanted TB VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$11,645,061September 30, 2021September 30, 2025EVANS, JAYreporter.nih.gov
KwaZulu-Natal Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$11,302,268December 1, 2024November 30, 2027ABDOOL KARIM, QUARRAISHAreporter.nih.gov
Wits HIV Research Group CLINICAL TRIAL UNIT (CTU) reapplicationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$11,202,199March 15, 2007September 21, 2025SANNE, IAN MATTHIASreporter.nih.gov
Advancing Vaccine Adjuvant Research for Tuberculosis (TB)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$10,964,476September 30, 2022September 29, 2027BRITTON, WARWICKreporter.nih.gov
Johns Hopkins University Baltimore India Clinical Trail Unit (JHUBI CTU)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$10,947,708February 5, 2007November 30, 2027GUPTA, AMITAreporter.nih.gov
Reagent Program for HIV and other Infectious DiseasesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$10,735,388October 15, 2023January 13, 2024RASHID, SUJATHAreporter.nih.gov
Administrative Supplement Request for 2025 Systems Biology for Infectious Diseases Annual MeetingNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$10,511,156August 17, 2018May 31, 2028KROGAN, NEVAN Jreporter.nih.gov
Thailand HIV/AIDS and Infectious Disease Clinical Trials Unit (THAI CTU)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$10,070,868March 15, 2007November 30, 2027SUPPARATPINYO, KHUANCHAIreporter.nih.gov
The Military HIV Research Program (MHRP) Clinical Trial UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$9,910,676December 10, 2013November 30, 2027ROBB, MERLIN Lreporter.nih.gov
Botswana-Harvard T.H. Chan School of Public Health AIDS Initiative Partnership CTUNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$9,824,534February 1, 2007June 30, 2025LOCKMAN, SHAHINreporter.nih.gov
GHESKIO Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$9,655,243February 1, 2007November 30, 2027PAPE, JEAN WILLIAMreporter.nih.gov
DEVELOPMENT OF UM-1098: A NOVEL SYNTHETIC TH17 INDUCING ADJUVANT AND DELIVERY SYSTEMNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$9,566,206September 30, 2023September 29, 2026EVANS, JAYreporter.nih.gov
FEND for TB supplement to accelerate BLINK X developmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$8,340,332June 4, 2020May 31, 2025ELLNER, JERROLD J.reporter.nih.gov
San Francisco Bay Clinical Trials Unit (CTU)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$8,314,128March 2, 2007November 30, 2027BUCHBINDER, SUSANreporter.nih.gov
The FIOCRUZ Therapeutic and Prevention HIV/AIDS Clinical Trials Unit.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$8,239,326January 15, 2008November 30, 2027GRINSZTEJN, BEATRIZreporter.nih.gov
Seattle Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$7,698,581February 1, 2007November 30, 2027MCELRATH, MARGARET JULIANAreporter.nih.gov
FEND for TBNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$7,632,771June 4, 2020May 31, 2026ELLNER, JERROLD J.reporter.nih.gov
The International URBAN Alcohol Research Collaboration on HIV/AIDS (ARCH) CenterNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$7,511,308September 10, 2021August 31, 2027SAMET, JEFFREY H.reporter.nih.gov
Harmonist: A Scalable Toolkit for Standardizing and Coordinating Data Sharing Across International Research NetworksNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$7,298,694May 25, 2016April 30, 2027DUDA, STEPHANY NORAHreporter.nih.gov
Aurum Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,678,965December 1, 2020November 30, 2027CHURCHYARD, GAVIN JOHNreporter.nih.gov
Stellenbosch University Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,524,563April 15, 2007November 30, 2027HESSELING, ANNEKE CATHARINAreporter.nih.gov
METABOLIC ALDEHYDES AS IMMUNE EFFECTORS AGAINST TUBERCULOSISNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,434,161September 11, 2025August 31, 2029DARWIN, KATERINA HERANreporter.nih.gov
Harnessing B cells for TB vaccine development to improve therapy of TB and TB-HIV coinfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,398,428July 1, 2021June 30, 2027GENGENBACHER, MARTIN ALFONSreporter.nih.gov
Evaluation of new diagnostics for incident, active and recurrent TB (ENDx-Tb)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,559,114June 17, 2020January 31, 2027WALZL, GERHARDreporter.nih.gov
DRAMATIC Phase 2 Duration Randomized MDR-TB Treatment TrialNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,484,466August 21, 2020May 31, 2026NAHID, PAYAMreporter.nih.gov
Chicago Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,330,849February 1, 2007November 30, 2027ACHENBACH, CHAD Jreporter.nih.gov
Supplement to G20AI67347 to complete critical upgrades to the Rutgers RBLNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$5,241,770August 22, 2022February 29, 2024ALLAND, DAVIDreporter.nih.gov
Deep spatial immune profiling of granulomas and M. tuberculosis adaptation to disease and treatmentNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,831,256December 1, 2021November 30, 2026RENGARAJAN, JYOTHIreporter.nih.gov
Novel Stem Cell Immunotherapy for MDR-TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,800,190June 4, 2021May 31, 2026JAGANNATH, CHINNASWAMYreporter.nih.gov
Rapid Research for Diagnostics Development in TB Network: Episode 2 (R2D2 TB Network II)NIHNational Institute of Allergy and Infectious Diseases2025$4,760,584September 23, 2025August 31, 2030NAHID, PAYAMreporter.nih.gov
PRESCIENT: A phase IIc, open-label, randomized controlled trial of ultra-short course bedaquiline, clofazimine, pyrazinamide and delamanid versus standard therapy for drug-susceptible tuberculosisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,716,636May 1, 2025April 30, 2027KOENIG, SERENA PATRICIAreporter.nih.gov
Clinical Trial Site Monitoring for PHOENIx MDR-TBNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,653,435April 15, 2025December 14, 2025SMITH, KIMBERLYreporter.nih.gov
MYCOBACTERIUM TUBERCULOSIS (MTB) QUALITY ASSESSMENT PROGRAM (TBQA)NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$4,608,548January 1, 2023December 31, 2023COFFIN, JEANETTEreporter.nih.gov
T cell recognition of the MR1 presented microbial metabolomeNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$4,523,152July 10, 2019June 30, 2025ADAMS, ERIN JUNEreporter.nih.gov
Impact of tuberculosis on the development and function of the immune system in SIV-infected infantsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$4,476,086April 1, 2019March 31, 2025WANG, XIAOLEIreporter.nih.gov
A systems analysis of drug tolerance in Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,414,678December 1, 2016June 30, 2027BALIGA, NITIN Sreporter.nih.gov
Inflammation and Fibrosis in Pulmonary TB: the INFIN-TB StudyNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,248,593July 1, 2025June 30, 2027AULD, SARAreporter.nih.gov
Preventing TB with intravenous BCG in SIV-infected macaquesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,248,442May 5, 2021April 30, 2026SCANGA, CHARLES A.reporter.nih.gov
The Role of Lipid-specific T cells in Mediating Protection Against M. tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,208,331June 1, 2020July 31, 2030SESHADRI, CHETANreporter.nih.gov
The Long-Acting/Extended Release Antiretroviral Resource Program (LEAP)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,204,220May 15, 2015June 30, 2030FLEXNER, CHARLES W.reporter.nih.gov
Capturing spatial patterns of new M. tuberculosis infection in Kampala, UgandaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,188,624August 9, 2019July 31, 2026BARK, CHARLES MARTYNreporter.nih.gov
Role of Inducible Bronchus Associated Lymphoid Tissue in Latent TuberculosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$4,152,012February 1, 2023January 31, 2027KHADER, SHABAANA A.reporter.nih.gov
Mechanisms of Helicases, Translocases and SSB Proteins involved in Genome MaintenanceNIHNational Institute of General Medical Sciences2021 to 2025$4,120,970May 1, 2020July 31, 2030LOHMAN, TIMOTHY Mreporter.nih.gov
A STINGing vaccine for TBNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,090,805June 1, 2020May 31, 2026BISHAI, WILLIAM RAMSESreporter.nih.gov
Childhood Omics and Mycobacterium tuberculosis-derived BiOsignatures (COMBO) for TB diagnosis in high HIV prevalence settingsNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$4,076,080April 22, 2020August 31, 2025CATTAMANCHI, ADITHYAreporter.nih.gov
Optimizing Multi-drug Mycobacterium tuberculosis Therapy for Rapid Sterilization and Resistance SuppressionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$4,042,959January 25, 2023December 31, 2027LOUIE, ARNOLDreporter.nih.gov
Structure/Function of Transcription Complex RegulationNIHNational Institute of General Medical Sciences2021 to 2025$4,041,062July 1, 1987August 31, 2027LANDICK, ROBERTreporter.nih.gov
Development of a novel TB vaccine safer and more effective than BCG based on a precisely controlled replication-limited Mycobacterium tuberculosis engineered for optimal in vivo growth and clearanceNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,876,556March 15, 2021February 28, 2027HORWITZ, MARCUS AARONreporter.nih.gov
Ribosome Structure and FunctionNIHNational Institute of General Medical Sciences2021 to 2025$3,829,940April 1, 2016March 31, 2027NOLLER, HARRY Freporter.nih.gov
Advanced Genotypic and Phenotypic monitoring of Drug Resistant TB to Improve TB Treatment OutcomesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,809,183August 1, 2015July 31, 2030LARSEN, MICHELLE Hreporter.nih.gov
Point-of-care C-reactive protein-based tuberculosis screening in people living with HIV: a randomized trialNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,789,374September 15, 2019May 31, 2025YOON, CHRISTINAreporter.nih.gov
Bacteria and Host in TB TransmissionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$3,731,271April 10, 2020March 31, 2023ALLAND, DAVIDreporter.nih.gov
Discovery of Adjuvants that Direct T-cell Fates for Improved Safety and Efficacy in Vaccines Against Influenza and TuberculosisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,714,524September 30, 2025September 29, 2026ESSER-KAHN, AARONreporter.nih.gov
Conduct Synthesis and Acquire Batches of Compounds for Subsequent Biological In Vitro and In Vivo TestingNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,702,250April 1, 2024March 31, 2025MIDDLETON, MARKreporter.nih.gov
Immunometabolic impact of stress hyperglycemia on tuberculosis treatment outcomes and risk of diabetes mellitusNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,694,016March 4, 2021February 28, 2027MAGEE, MATTHEW JAMESreporter.nih.gov
Mtb and HIV/SIV antigen peptide signatures as blood biomarkers to detect early infection to active disease in young children and NHPNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,693,137May 1, 2021March 31, 2027LYON, CHRISTOPHER Jreporter.nih.gov
The Bring BPaL2Me Trial - Comparing Nurse-Led RR-TB Treatment in Primary Care to Physician-Led, Hospital-Based RR-TB Treatment: A Cluster Randomized, Non-Inferiority TrialNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,655,506March 10, 2023February 29, 2028FARLEY, JASON EDWARDreporter.nih.gov
Effects of HIV SIV on unconventional T cells in immunity to M. tuberculosis in pre adolescentsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,631,144March 4, 2019February 28, 2025SCANGA, CHARLES A.reporter.nih.gov
Mechanisms of cough in Mycobacterium tuberculosis transmissionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,611,276March 8, 2021February 28, 2026SHILOH, MICHAELreporter.nih.gov
Synthetic Nanoparticle-antibody (SNAb) Based Depletion of Myeloid-Derived Suppressor Cells for TB Host-Directed TherapyNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,610,454August 5, 2021July 31, 2025RENGARAJAN, JYOTHIreporter.nih.gov
Molecular Analysis of Host Immune Response in LeprosyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,593,035January 1, 1991May 31, 2029MODLIN, ROBERT Lreporter.nih.gov
Hodgkin Lymphoma in PLWH in South Africa: TB, EBV, and Tumor Molecular MarkersNIHNational Cancer Institute2021 to 2024$3,536,890April 1, 2020September 30, 2025AMBINDER, RICHARD FREDERICKreporter.nih.gov
Defining adaptive immune responses to Mtb-infection and TB disease among young children with and without HIV-exposureNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,527,794April 15, 2021March 31, 2027LANCIONI, CHRISTINA LOUISEreporter.nih.gov
Safety and Tolerability of Ultra-short Course Rifapentine and Isoniazid (1HP) for Prevention of Tuberculosis in HIV-Uninfected IndividualsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,492,579August 1, 2020May 31, 2026CHAISSON, RICHARD E.reporter.nih.gov
Targeting TB transmission hotspots to find undiagnosed TB in South Africa: a genomic, geospatial and modeling study (TARGET- TB)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,433,190May 1, 2025April 30, 2027MATHEMA, BARUNreporter.nih.gov
Mycobacterium Tuberculosis (MTB) Quality Assessment Program (TBQA)NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,397,377November 17, 2024November 16, 2025OLINGER, GENE GARRARDreporter.nih.gov
Socio-spatial Networks and Tuberculosis Infection in Youth in Rural UgandaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,369,946November 16, 2020October 31, 2026MARQUEZ, CARINAreporter.nih.gov
M. tuberculosis exosome detection for pediatric TB diagnosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,323,600June 1, 2025May 31, 2027LACOURSE, SYLVIAreporter.nih.gov
TB Meningitis: Evaluating CSF Immunology to Discover Hidden Disease and Potential Immunomodulatory TherapiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,322,837August 1, 2021July 31, 2026BOULWARE, DAVID Rreporter.nih.gov
Bacteria and Host in TB TransmissionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,309,466April 10, 2020March 31, 2026ALLAND, DAVIDreporter.nih.gov
Lesion-centric optimization of multidrug therapies for tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,301,434January 15, 2020December 31, 2025ALDRIDGE, BREE BEARDSLEYreporter.nih.gov
Role of Ubiquitin Ligases and Deubiquitinases in Host Defense against Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2025$3,278,392August 21, 2025July 31, 2029SHILOH, MICHAELreporter.nih.gov
Informing Drug Synergy: Investigating Mycobacterial Membrane Protein Structure and FunctionNIHNational Institute of Allergy and Infectious Diseases2025$3,262,539August 1, 2025July 31, 2029REGO, ELIZABETH HESPERreporter.nih.gov
Glutamine metabolism inhibitors for TB and TB-HIV: dual action as host-directed therapies with antibacterial activityNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,255,352September 16, 2020August 31, 2025BISHAI, WILLIAM RAMSESreporter.nih.gov
Genetic, Metabolic and Regulatory Control of MIC and Relapse in M. tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,249,590March 10, 2020February 28, 2026SHERMAN, DAVID Rreporter.nih.gov
Video DOT and Economic Incentives to promote adherence to LTBI therapyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,246,780July 8, 2021June 30, 2027SHAH, MAUNANKreporter.nih.gov
PROgression of Tuberculosis infECTion in young children living with and without HIV: the PROTECT studyNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,235,332April 1, 2023March 31, 2028CATTAMANCHI, ADITHYAreporter.nih.gov
Novel Methods to Inform HIV/TB Clinical Trial DevelopmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,228,180September 1, 2011August 31, 2025REDDY, KRISHNA Preporter.nih.gov
Identification of Novel Syk/Raf-1 Mediated CLR Ligands as Vaccine AdjuvantsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,198,798September 30, 2025September 29, 2026EVANS, JAYreporter.nih.gov
Dual Targeting of Mtb Resistance MechanismsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,194,513September 22, 2020August 31, 2025GRUNDNER, CHRISTOPHreporter.nih.gov
Elucidating the path to type I IFNs in TB infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,182,185April 1, 2021March 31, 2026BARCZAK, AMY Kreporter.nih.gov
An Enhanced Package of Care to Reduce Mortality in Persons with Advanced HIV DiseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,179,431August 23, 2021July 31, 2026RAJASINGHAM, RADHAreporter.nih.gov
Biomarker Signatures of TB Infection in Young Children With and Without HIVNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,173,148April 28, 2023March 31, 2028SALGAME, PADMINIreporter.nih.gov
Preclinical modeling to study Tuberculous MeningitisNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,172,738April 1, 2020March 31, 2026JAIN, SANJAYreporter.nih.gov
Improving Diagnostics and Neurocognitive Outcomes in HIV/AIDS-related MeningitisNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,153,952September 1, 2013May 31, 2029BOULWARE, DAVID Rreporter.nih.gov
Urine Colorimetry for Tuberculosis Pharmacokinetics Evaluation in Children and AdultsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,153,883September 24, 2018October 31, 2028HEYSELL, SCOTT Kreporter.nih.gov
Macrophage senescence as a driver of granuloma failure and progression to necrosis in TB and TB/HIVNIHNational Institute of Allergy and Infectious Diseases2025$3,145,850September 19, 2025August 31, 2029BISHAI, WILLIAM RAMSESreporter.nih.gov
Multiplexed Antigen-Specific Antibody Fc Profiling on a Chip for Point-of-Care Diagnosis of TB in HIV-infected ChildrenNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,139,781May 6, 2020April 30, 2026BRYSON, BRYAN DAVIDreporter.nih.gov
Discovery of Phospopantetheinyl Transferse Inhibitors Against Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,136,573July 13, 2021June 30, 2025AUBE, JEFFREYreporter.nih.gov
A New Approach to an Old Problem: Redesigning Latent Tuberculosis Screening and TreatmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,126,853March 17, 2020February 28, 2026TARTOF, SARAreporter.nih.gov
FEND-TBNIHNational Institute of Allergy and Infectious Diseases2025$3,089,360September 10, 2025August 31, 2030ELLNER, JERROLD J.reporter.nih.gov
Tailoring modifications of polysaccharides in Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,062,061September 17, 2021August 31, 2027JACKSON, MARYreporter.nih.gov
Mechanisms of Innate Immune Evasion by Mycobacterium TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,061,547January 1, 2017December 31, 2026PHILIPS, JENNIFER Areporter.nih.gov
Immunometabolic regulations of pulmonary TB pathogenesis by adiposetissueNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,053,206January 10, 2020December 31, 2025NAGAJYOTHI, JYOTHI FALGUNIreporter.nih.gov
Assembly and export of mycobacterial lipoglycansNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,040,802June 10, 2021May 31, 2027JACKSON, MARYreporter.nih.gov
Enhancing cytotoxic lymphocytes in a TB vaccine strategyNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,037,076February 25, 2022January 31, 2027FLYNN, JOANNE L.reporter.nih.gov
Therapeutic vaccination to augment stringent response-specific T-cell immunity to MTB persistersNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,027,518March 17, 2020February 28, 2025KARAKOUSIS, PETROS Creporter.nih.gov
Chemical Biological Discovery of Lipid Virulence Factors in the Major Bacterial PathogensNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,024,614June 22, 2022May 31, 2027MOODY, DAVID BRANCHreporter.nih.gov
Measuring Intralesional Drug Exposures in Cavitary TB using Noninvasive In Vivo PET ImagingNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,024,535July 1, 2020June 30, 2025JAIN, SANJAYreporter.nih.gov
Dissecting the pathogenesis of HIV-TB Immune reconstitution inflammatory syndromeNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,018,989August 17, 2020July 31, 2026LIN, PHILANA LINGreporter.nih.gov
Analysis of Chemical Structures and Therapeutic Activity of Agents for HIV, TB, and HBV (CHEMDB)NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,016,918September 30, 2024September 29, 2025SUMNER, LOUISEreporter.nih.gov
Regional Prospective Observational Research in Tuberculosis (RePORT) – Brazil NetworkNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,000,000January 2, 2023December 31, 2027STERLING, TIMOTHY Rreporter.nih.gov
Improving diagnostic sensitivity for difficult-to-lyse microbial samples with nanodroplet technologyNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,995,731August 3, 2020April 30, 2026KASOJI, SANDEEPreporter.nih.gov
Lab-on-a-Film Multiplexed Test for Respiratory Mycobacterial InfectionsNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,995,164April 21, 2021July 31, 2025COONEY, CHRISTOPHER GERARDreporter.nih.gov
Heterocyclic Inhibitors of QcrB as Novel Drugs for TuberculosisNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,992,852December 13, 2019November 30, 2024HANNAN, THOMAS JOSEPHreporter.nih.gov
Teixobactin Development for TuberculosisNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,988,753September 1, 2022August 31, 2025HUGHES, DALLASreporter.nih.gov
The role of FENDRR in host defense against Mycobacterium tuberculosis infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,963,619September 21, 2022July 31, 2027CHENG, YONGreporter.nih.gov
Handheld and population-based sequencing for rapid detection of new and repurposed drug resistance in M. tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,952,078March 1, 2025February 28, 2027METCALFE, JOHN ZAPATAreporter.nih.gov
Understanding resistance and tolerance to nitroimidazoles in Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2025$2,944,529July 23, 2025June 30, 2029SCHNAPPINGER, DIRKreporter.nih.gov
Investigating bacterial contributions to TB treatment response: a focus on in-host pathogen dynamicsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,943,133September 22, 2020August 31, 2025FARHAT, MAHAreporter.nih.gov
Characterization of the nutrient assimilation pathways in M. tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,936,418November 19, 2020October 31, 2025VANDERVEN, BRIAN Creporter.nih.gov
Advancing Apoptosis-Inducing Agents as Host-Directed Therapy for TBNIHNational Institute of Allergy and Infectious Diseases2025$2,922,220September 3, 2025August 31, 2029KARAKOUSIS, PETROS Creporter.nih.gov
Targeting Membrane Transport Steps in Cell Envelope AssemblyNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,914,356May 21, 2020July 31, 2025KAHNE, DANIELreporter.nih.gov
Translational approaches to improve understanding and outcome in Tuberculous meningitisNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,879,850March 19, 2020March 31, 2026GENGENBACHER, MARTIN ALFONSreporter.nih.gov
A multifactorial pipeline to dissect combinatorial drug efficacy in TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,868,530August 9, 2021July 31, 2025SHERMAN, DAVID Rreporter.nih.gov
Emergence of bedaquiline and clofazimine resistance after interruption of drug-resistant TB therapy in a high HIV prevalence settingNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,868,143December 26, 2019November 30, 2026BRUST, JAMES C Mreporter.nih.gov
Mechanisms of CD4 T cell help to myeloid cells in tuberculosisNIHNational Institute of Allergy and Infectious Diseases2025$2,863,501August 1, 2025July 31, 2029BOLD, TYLER DALLASreporter.nih.gov
Strengthening evidence on optimal multidrug-resistant tuberculosis treatment regimens through improved epidemiologic methodsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,850,504May 1, 2020April 30, 2026FRANKE, MOLLY FORRESTreporter.nih.gov
Design, Syntheses and Studies of Novel Antituberculosis AgentsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,840,145September 1, 2021August 31, 2026MILLER, MARVIN Jreporter.nih.gov
Differentially Culturable Tubercle Bacteria: The missing link in TB Transmission?NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,838,851September 1, 2019August 31, 2025KANA, BAVESH DAVANDRAreporter.nih.gov
HIV, gestational diabetes and TB in pregnancyNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,837,523July 15, 2022June 30, 2027MATHAD, JYOTI Sreporter.nih.gov
Network Dissection of Host-Pathogen Interactions in Mycobacterium tuberculosis InfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,827,500August 3, 2021July 31, 2026MA, SHUYIreporter.nih.gov
Aerobiology, immunology, and Mycobacterium tuberculosis transmissionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,825,908July 10, 2020June 30, 2025HORNE, DAVID J.reporter.nih.gov
Large Scale T Cell Epitope Discovery: Proteome-wide characterization of T cell epitopes from Mycobacterium tuberculosis in vaccination and active infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,815,378September 30, 2019September 29, 2023PETERS, BJOERNreporter.nih.gov
Chemical Probes of MycobacteriaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,777,928February 1, 2017March 31, 2027KIESSLING, LAURA Lreporter.nih.gov
Necrosis in Pulmonary TB granulomas: dynamics, mechanisms, and therapiesNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,774,492May 1, 2016February 28, 2026KRAMNIK, IGORreporter.nih.gov
Undetected Drug resistance and Tolerance in lesions of recurrent TBNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,771,822July 1, 2022June 30, 2027VALAFAR, FARAMARZreporter.nih.gov
Multi-level and Intersectional Stigma and other Social Determinant Effects on TB Case Detection, Care, and Treatment Outcomes: The MISSED TB Outcomes StudyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,767,378December 1, 2020November 30, 2026MEDINA-MARINO, ANDREWreporter.nih.gov
Role of Inducible Bronchus Associated Lymphoid Tissue in Latent TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,754,890April 1, 2015September 1, 2022KHADER, SHABAANA A.reporter.nih.gov
Linking Human TB Genetic Susceptibility Loci to Granuloma BiologyNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,749,788January 11, 2022December 31, 2026TOBIN, DAVID M.reporter.nih.gov
Poor Treatment Response and Outcomes in Bedaquiline-Based Treatment Regimens for Drug-Resistant Tuberculosis in South AfricaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,735,126April 1, 2021March 31, 2027VAN DER HEIJDEN, YURI F.reporter.nih.gov
Adjuvant Development in the context of a vaccine to protect against tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,722,493September 30, 2018September 29, 2023PETROVSKY, NIKOLAIreporter.nih.gov
Generation of a Complete Set of Precise Null Bar-Coded Deletion Mutants of Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,711,266September 14, 2017June 30, 2028JACOBS, WILLIAM ROBERTreporter.nih.gov
Hybrid trial for Alcohol reduction among people with TB and HIV in India (HATHI)NIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$2,710,996September 5, 2020May 31, 2025GUPTA, AMITAreporter.nih.gov
Regulation of innate immunity by self-adjuvated MRNA vaccinesNIHNational Institute of Allergy and Infectious Diseases2025$2,710,680August 12, 2025May 31, 2029JAGANNATH, CHINNASWAMYreporter.nih.gov
Development of Inhaled CPZEN-45 For Tuberculosis TherapyNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,694,338March 1, 2019February 28, 2025SEVERYNSE-STEVENS, DIANA Mreporter.nih.gov
Improving rapid phenotypic drug susceptibility testing for drug resistant tuberculosis in high-burden areasNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,692,722April 6, 2023August 8, 2025TORRELLES, JORDI Breporter.nih.gov
Targeted cell-depleting immunotherapy for TB and HIVNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,691,184February 25, 2020January 31, 2026BISHAI, WILLIAM RAMSESreporter.nih.gov
Pattern Recognition Receptors and Autophagy in Mtb Control in AIDSNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,686,330April 1, 1998March 31, 2028DERETIC, VOJO Preporter.nih.gov
Early and accurate diagnosis of pulmonary and extrapulmonary tuberculosis in all patient groups using a circulating pathogen-derived antigenNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,685,056August 25, 2021July 31, 2025TOMBLER, THOMAS Wreporter.nih.gov
Th9 cells and protective TB immunityNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,670,376March 9, 2022February 28, 2027HOFT, DANIEL F.reporter.nih.gov
Characterizing Macrophages as "Hide-Outs" for Chronic PathogensNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,655,871August 1, 2021July 31, 2027CLAYTON, KIERA L.reporter.nih.gov
Mycobacterial DNA repair and mutagenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,655,624February 1, 2005May 31, 2025GLICKMAN, MICHAEL Sreporter.nih.gov
Evaluating smoking cessation interventions for PWH in South Africa: Efficacy, implementation, and cost-effectiveness.NIHNational Cancer Institute2021 to 2025$2,653,805September 15, 2021August 31, 2027GOLUB, JONATHAN E.reporter.nih.gov
Immune correlates of tuberculosis and non-tuberculosis infectious morbidity in Southern African HIV-exposed, uninfected infants.NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,651,462February 13, 2019January 31, 2025POWIS, KATHLEENreporter.nih.gov
A randomized clinical trial of early empiric anti-Mycobacterium tuberculosis therapy for sepsis in sub-Saharan AfricaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,649,150September 18, 2020June 30, 2025HEYSELL, SCOTT Kreporter.nih.gov
Detecting pathogen and host factors on extracellular vesicles for pediatric TB diagnosis and managementNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,633,435March 17, 2017June 30, 2028HU, TONY Y.reporter.nih.gov
Lung immune function in human TB infection and its perturbation by HIV-1.NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,627,712June 4, 2020May 31, 2025RUSSELL, DAVID Greporter.nih.gov
Tobacco Use and Cessation, HIV, and TB in South Africa: Clinical and Economic Outcomes (Clinical and public health approaches to tobacco cessation in South Africa supplement)NIHNational Institute on Drug Abuse2021 to 2024$2,627,377September 1, 2020July 31, 2025REDDY, KRISHNA Preporter.nih.gov
Immunogenetic predictors of active and incipient TB in HIV-negative and -positive close TB contactsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,623,121June 17, 2019May 31, 2025STERLING, TIMOTHY Rreporter.nih.gov
Using the Mycobacterium tuberculosis Genome to Predict Tuberculosis Pathology, Drug Resistance Acquisition and Identify Community Transmission SitesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,610,785April 15, 2020March 31, 2026GILMAN, ROBERT Hreporter.nih.gov
Dynamics of the cellular and molecular architecture of human pulmonary TB granulomasNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,600,654February 10, 2022January 31, 2027MODLIN, ROBERT Lreporter.nih.gov
Who are the Ultra-positive, culture-negative? Understanding the trajectories of individuals in Uganda with trace M. tuberculosis nucleic acid in sputumNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,597,618September 15, 2020August 31, 2025KENDALL, EMILY Areporter.nih.gov
Strategies for tuberculosis control in prisonsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,581,087March 1, 2017February 29, 2028ANDREWS, JASON RANDOLPHreporter.nih.gov
ULTIMATENIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,579,550April 1, 2019March 31, 2024VAN CREVEL, REINOUTreporter.nih.gov
Improved understanding of TB transmission by accounting for within-host heterogeneity of M. tuberculosis: A population-based molecular epidemiology study in a high HIV prevalent settingNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,579,446February 7, 2020January 31, 2026SHIN, SANGHYUK SAMreporter.nih.gov
Functional dynamics of TB granuloma architectureNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,566,261March 18, 2022February 28, 2027ERNST, JOEL D.reporter.nih.gov
Lung-Protective Mechanisms of Metformin in TBNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,548,097February 5, 2021January 31, 2026KORNFELD, HARDYreporter.nih.gov
MYCOBACTERIUM TUBERCULOSIS PROTEOME-WIDE EPITOPE DISCOVERY AND HOST TRANSCRIPTOME-WIDE T CELL PHENOTYPING IN HIGH DISEASE BURDEN POPULATIONSNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,545,675September 30, 2025September 29, 2026ALTIN, JOHNreporter.nih.gov
Genome-Wide Dissection of Mendelian Susceptibility to Mycobacterial DiseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,542,500May 1, 2011April 30, 2027CASANOVA, JEAN-LAURENTreporter.nih.gov
Functionally distinct human CD4 T cell responses to novel evolutionarily selected M. tuberculosis antigensNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,540,587July 1, 2023June 30, 2028ERNST, JOEL D.reporter.nih.gov
Sirtuins and Host Metabolism in TB Pathogenesis and TreatmentNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,537,961April 15, 2021March 31, 2026KORNFELD, HARDYreporter.nih.gov
Sirtuin -Dependent Regulation of Tuberculosis and HIV Interactions in MacrophagesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,534,348August 1, 2024July 31, 2029JAGANNATH, CHINNASWAMYreporter.nih.gov
B12 Trafficking and Inherited DefectsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,532,174February 1, 1998January 31, 2028BANERJEE, RUMA Vreporter.nih.gov
The role of tyrosine metabolism in tuberculosis pathogenesisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,518,656February 21, 2023January 31, 2028SULIMAN, SARAreporter.nih.gov
Minimally Invasive Tissues Sampling to Evaluate HIV-associated Meningitis in ZambiaNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,516,061June 15, 2022April 30, 2027SIDDIQI, OMAR KHALIKreporter.nih.gov
MmpL3 as a target for novel anti-TB agentsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,515,476June 15, 2015March 31, 2026JACKSON, MARYreporter.nih.gov
Excess cardiovascular inflammation in TB and HIV: EXFIN-TBNIHNational Heart, Lung, and Blood Institute2025$2,513,201September 1, 2025August 31, 2029BISSON, GREGORY P.reporter.nih.gov
Second Generation InSTIs for the Treatment of HIV-1 in patients with TB co-infection on Rifampicin-based Treatment in KwaZulu Natal, South AfricaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,508,444August 3, 2020July 31, 2025NAIDOO, ANUSHKAreporter.nih.gov
The effect of HIV exposure and infection on immunity to TB in childrenNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,482,220January 1, 2019December 31, 2025JOHN-STEWART, GRACE C.reporter.nih.gov
Development of Therapeutic Candidates for Biodefense, Antimicrobial Resistant (AMR) Infections and Emerging Infectious DiseasesNIHNational Institute of Allergy and Infectious Diseases2024$2,475,623May 10, 2024November 9, 2025FOTOUHI, NADERreporter.nih.gov
Chemical genetics of M. tuberculosis DosRST signaling and persistenceNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,472,195September 22, 2020August 31, 2025ABRAMOVITCH, ROBERT Breporter.nih.gov
Novel and Optimized Diagnostics for Pediatric TBNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,461,700May 7, 2020April 30, 2023ELLNER, JERROLD J.reporter.nih.gov
Novel and Optimized Diagnostics for Pediatric TBNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$2,451,069May 7, 2020April 30, 2026ELLNER, JERROLD J.reporter.nih.gov
TB AftermathNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,441,657June 1, 2020May 31, 2027GOLUB, JONATHAN E.reporter.nih.gov
Genetic and hormonal mechanisms mediating sex differences in TB and TB-HIVNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,441,514February 1, 2022January 31, 2028BISHAI, WILLIAM RAMSESreporter.nih.gov
Identifying correlates of risk for future tuberculosis disease progression in children (INTREPID)NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,440,431May 1, 2025April 30, 2028SEDDON, JAMES ALEXANDERreporter.nih.gov
T cell responses to CD1-restricted lipids in tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,419,239March 1, 2001February 28, 2026MOODY, DAVID BRANCHreporter.nih.gov
Host blood biomarkers for the diagnosis prognosis and treatment response of childhood TBNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,409,972February 20, 2019January 31, 2025HATHERILL, MARKreporter.nih.gov
M. tuberculosis carbon metabolism during infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,408,722June 2, 2023May 31, 2028EHRT, SABINEreporter.nih.gov
Manipulation of the host cell inflammasome by Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,406,844June 8, 2021May 31, 2027BRIKEN, VOLKERreporter.nih.gov
Optimization and Advanced Proof-of-Concept Studies of a Listeria-vectored Multi-Antigenic Vaccine against TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,406,319December 1, 2017November 30, 2025HORWITZ, MARCUS AARONreporter.nih.gov
Defining the Immunogenicity and Efficacy of a Durable BCG Vaccine Strategy Optimized for Preventing TB in Pediatric HIV InfectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,404,290July 20, 2023June 30, 2028SCANGA, CHARLES A.reporter.nih.gov
Epigenetic & Post-Translational Mechanisms of Macrophage Resistance to Mycobacterium tuberculosis During HIV Co-InfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,399,976April 1, 2018March 31, 2024HAWN, THOMAS Rreporter.nih.gov
Host-Directed Therapy to Augment anti-M. tuberculosis Responses in the Setting of HIV Co-infection and to Sterilize the TuberculomaNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$2,391,699May 16, 2018April 30, 2025MEHRA, SMRITIreporter.nih.gov
PROTEASOMAL REGULATION AND PROTEIN QUALITY CONTROL IN M. TUBERCULOSISNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,390,710December 1, 2010March 31, 2026DARWIN, KATERINA HERANreporter.nih.gov
A Global Research Resource for Human TuberculosisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,389,377June 18, 2024May 31, 2029STEYN, ADRIE JCreporter.nih.gov
A Preclinical Program for Targeting Mycobacterium tuberculosis KasANIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,385,783August 10, 2021July 31, 2026FREUNDLICH, JOEL STEPHENreporter.nih.gov
Development of a Self Inactivating, Highly Effective TB VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,381,016February 6, 2019January 31, 2024FLYNN, JOANNE L.reporter.nih.gov
Chemical MycobateriologyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,380,609September 1, 2025August 31, 2026BERTOZZI, CAROLYNreporter.nih.gov
Bacterial disruption of neuroimmune pathways in a transparent brainNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,370,000September 15, 2021August 31, 2026MADIGAN, CRESSIDA ARIANNAreporter.nih.gov
Molecular Genetic Analysis of Mycobacterium TuberculosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,368,749December 1, 1988August 31, 2028JACOBS, WILLIAM ROBERTreporter.nih.gov
RNA modification and antibiotic resistanceNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,361,815May 1, 2010April 30, 2026CONN, GRAEME Lreporter.nih.gov
Macrophage nuclear receptors, metabolism and immune effectors during health and M. tuberculosis infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,354,572August 7, 2019July 31, 2030SCHLESINGER, LARRY S.reporter.nih.gov
Targeting Biotin Metabolism in Mycobacterium TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,339,589January 15, 2019December 30, 2023ALDRICH, COURTNEY Creporter.nih.gov
Cavity and Granuloma Oriented Inflammation and Tissue Pharmacokinetics in Pulmonary Tuberculosis (COOK TB)NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,339,351February 9, 2023January 31, 2028KEMPKER, RUSSELL RYANreporter.nih.gov
Characteristics and protective efficacy of human antibodies against M. tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,338,122July 1, 2019June 30, 2025ACHKAR, JACQUELINE MICHELEreporter.nih.gov
Hypoxia, tuberculosis, and T cell dysfunctionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,330,835June 1, 2023May 31, 2028BEHAR, SAMUEL Mreporter.nih.gov
Adaptive evaluation of mHealth and conventional adherence support interventions to optimize outcomes with new treatment regimens for drug-resistant tuberculosis and HIV in South AfricaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,326,177March 10, 2022February 28, 2027O'DONNELL, MAXreporter.nih.gov
Identifying TB transmitters in high TB/HIV burdened communitiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,325,597September 5, 2019August 31, 2025WOOD, ROBINreporter.nih.gov
Macrophage Reprogramming During Granuloma Formation in the ZebrafishNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,325,311March 3, 2017February 28, 2027TOBIN, DAVID M.reporter.nih.gov
One-carbon metabolism and immune cell function in tuberculosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,323,713August 2, 2023July 31, 2027SHI, LANBOreporter.nih.gov
Mechanisms of efficient control of Mycobacterium tuberculosis in the lungs prior to granulomaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,322,288July 9, 2024May 31, 2029KAUSHAL, DEEPAKreporter.nih.gov
Durability of systemic and lung immune correlates of BCG-induced protection against M. tuberculosis infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,311,437August 11, 2020July 31, 2026NEMES, ELISAreporter.nih.gov
Role of IL-17 in Protective Vaccine-induced Immune Responses Against TuberculosisNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,302,219December 15, 2010July 31, 2026KHADER, SHABAANA A.reporter.nih.gov
Genetic dissection of angiogenesis during mycobacterial infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,299,646February 15, 2017January 31, 2027TOBIN, DAVID M.reporter.nih.gov
Optimization and preclinical development of a TB Multiple Antigen Presenting System (MAPS) vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,298,018December 15, 2017November 30, 2023MALLEY, RICHARDreporter.nih.gov
Rapid phenotypic detection of complex and emergent TB drug-resistance using a next-generation nanoluciferase reporter phageNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,278,505April 3, 2023March 31, 2028O'DONNELL, MAXreporter.nih.gov
Emergence of bedaquiline, pretomanid and linezolid resistance after implementation of new drug-resistant tuberculosis regimens in South AfricaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,277,213November 25, 2022October 31, 2027MATHEMA, BARUNreporter.nih.gov
Coronary Atherosclerosis and Immune Activation in HIV and Tuberculosis InfectionNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,274,138August 2, 2022July 31, 2027HUAMAN JOO, MOISES ARTUROreporter.nih.gov
The impact of pyrazinamide on metabolism in Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,264,154March 10, 2021February 28, 2026BAUGHN, ANTHONY Dreporter.nih.gov
Tuberculosis Immunopathogenesis During Superinfection with SARS-CoV2NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,255,725May 15, 2023April 30, 2028TALAAT, ADEL Mreporter.nih.gov
Rapid Detection of TB from Blood using Cell-Free DNA and CRISPRNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,253,957July 17, 2023June 30, 2027RODWELL, TIMOTHY CHARLESreporter.nih.gov
New potent orally bioavailable nitro-containing compounds to treat mycobacterial infectionsNIHNational Institute of Allergy and Infectious Diseases2025$2,248,740July 7, 2025June 30, 2028ABRAMOVITCH, ROBERT Breporter.nih.gov
Prevent TB: Application of choice architecture to implement TB preventive therapy in South AfricaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,248,070February 28, 2020January 31, 2027HOFFMANN, CHRISTOPHER Jreporter.nih.gov
Mechanisms of vitamin A-dependent risk for tuberculosis progression and preventionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,246,313June 15, 2023May 31, 2028PODELL, BRENDANreporter.nih.gov
When are in-person HIV services worth the risk of COVID-19 and other communicable illnesses? Optimizing choices when virtual services are less effectiveNIHNational Institute of Mental Health2022 to 2024$2,244,785September 1, 2022July 31, 2027BERSHTEYN, ANNAreporter.nih.gov
A nanopore biosensor for leveling Mtb antigens in bloodNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,238,457June 15, 2022May 31, 2028LYON, CHRISTOPHER Jreporter.nih.gov
Chemical biology studies of MmpL3 inhibition and resistance in mycobacteriaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,236,678July 13, 2023June 30, 2028ABRAMOVITCH, ROBERT Breporter.nih.gov
Elucidating the mechanisms and consequences of MDSC-regulated immunity in TBNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,236,002July 22, 2022June 30, 2027MATTILA, JOSHUA T.reporter.nih.gov
Hotspot versus clinic-based active case finding for TB in Uganda: A pragmatic randomized trialNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,225,984August 15, 2017November 30, 2026KENDALL, EMILY Areporter.nih.gov
Automated Sequencing for Culture-free Diagnosis of Drug Resistant TBNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,220,441April 17, 2023March 31, 2028RODWELL, TIMOTHY CHARLESreporter.nih.gov
Autophagy Against Tuberculosis and HIVNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,218,437March 1, 2014February 28, 2026DERETIC, VOJO Preporter.nih.gov
Identifying Optimal Treatment Strategies for Tuberculosis TreatmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,217,092January 16, 2019December 31, 2024SAVIC, RADOJKAreporter.nih.gov
Toxin secretion and trafficking by Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,216,121July 17, 2023June 30, 2027NIEDERWEIS, MICHAELreporter.nih.gov
Post-TB epigenetic scars' impact on long-term inflammation, immunity and mortalityNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,213,177July 1, 2023June 30, 2028DINARDO, ANDREW Rreporter.nih.gov
Multiplexed detection of cell-free M. Tuberculosis DNA and its drug-resistant variants in bloodNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,202,681August 11, 2023July 31, 2028HUANG, ZHENreporter.nih.gov
Etiology of Persistent Microalbuminuria in NigeriaNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,202,068July 1, 2021May 31, 2026WESTER, C. WILLIAMreporter.nih.gov
An Antigen-Detection Blood Test for Pulmonary TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,200,977July 3, 2019June 30, 2025CATANZARO, ANTONINOreporter.nih.gov
Integrating genomic and spatial approaches for targeted control of HIV-associated tuberculosis epidemicsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,197,125August 1, 2020July 31, 2025COHEN, THEODORE Hreporter.nih.gov
Transmission Of Tuberculosis Among illicit drug use Linkages (TOTAL)NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,180,842August 1, 2019July 31, 2025JACOBSON, KAREN Rreporter.nih.gov
Bacterial and Molecular Determinants of Mycobacterial ImpermeabilityNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,177,331August 2, 2023July 31, 2028PIRES, MARCOS M.reporter.nih.gov
An RNA Nanosensor for the Diagnosis of Antibiotic Resistance in M. TuberculosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,172,351September 1, 2025August 31, 2028FARHAT, MAHAreporter.nih.gov
INTERCEPTNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,147,632January 1, 2022December 31, 2026VAN CREVEL, REINOUTreporter.nih.gov
Diagnostic Innovations for Pediatric Tuberculosis in BoliviaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,139,484June 1, 2025May 31, 2028OBERHELMAN, RICHARD Areporter.nih.gov
Optimization of Atypical Antimycobacterial Carbapenem AntibioticsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,139,287July 19, 2023June 30, 2028BUYNAK, JOHN Dreporter.nih.gov
A novel cartridge-based sequencing solution for decentralized M. tuberculosis resistance detectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,133,601July 7, 2023June 30, 2028METCALFE, JOHN ZAPATAreporter.nih.gov
Single-cell factors of tuberculosis drug tolerance during adaptation to environmental stressorsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,121,678April 1, 2020March 31, 2025ALDRIDGE, BREE BEARDSLEYreporter.nih.gov
Regulators of IFN-gamma responses during Mycobacterium tuberculosis infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,095,936July 6, 2022June 30, 2027OLIVE, ANDREWreporter.nih.gov
Human-centered Design and Communities of Practice to Improve Delivery of Home-based TB Contact Investigation in UgandaNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,074,247June 17, 2013December 31, 2024DAVIS, JOHN LUCIANreporter.nih.gov
Defining the antibody interface between Mycobacterium tuberculosis and host immunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,063,021September 23, 2021August 31, 2027LU, LENETTEreporter.nih.gov
Tuberculosis Research and Mentorship Program (TB RAMP II)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,053,078September 12, 2025August 31, 2030FAIR, ELIZABETHreporter.nih.gov
Redefining Tuberculosis Meningitis with Metagenomics and Host TransciptomicsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,043,168March 11, 2019February 28, 2025WILSON, MICHAEL Rreporter.nih.gov
Investigating alveolar macrophages in PLWH as targets for HIV persistence, residual inflammation and immune activationNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,041,080July 19, 2024June 30, 2029RENGARAJAN, JYOTHIreporter.nih.gov
The regulation and functions of Group 1 CD1-restricted T cellsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,036,996September 20, 2023July 31, 2028WANG, CHYUNG-RUreporter.nih.gov
Long Acting Injectable Depots for TB TherapyNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,013,687June 22, 2021May 31, 2024STAYTON, PATRICK S.reporter.nih.gov
Childhood ‘Omics’ and Mycobacterium tuberculosis-derived BiOsignatures (COMBO) for TB diagnosis in high HIV prevalence settingsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,008,838April 22, 2020December 31, 2022CATTAMANCHI, ADITHYAreporter.nih.gov
Targeting trans-translation to kill M. tuberculosis non-replicating persister cellsNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,004,012November 1, 2021April 30, 2024KEILER, KENNETH Creporter.nih.gov
Baseline pRescription According to Direct from Sputum Sequencing and TArgeted drug Concentration Strategy (BRASS TACS)NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,998,000April 7, 2023March 31, 2028TORNHEIM, JEFFREYreporter.nih.gov
Seattle-Lausanne Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,995,056February 1, 2007March 31, 2022MCELRATH, MARGARET JULIANAreporter.nih.gov
Optimal targeting for individual and population-level TB preventionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,986,197December 5, 2019November 30, 2025MENZIES, NICOLAS Areporter.nih.gov
Immunotherapeutic approach for the prevention of secondary infection with drug-resistant TBNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,956,687June 13, 2024April 30, 2029COLER, RHEA Nreporter.nih.gov
Interplay of M. tuberculosis trehalose metabolism and its pathogenesis and drug resistanceNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,953,308March 16, 2023February 28, 2027EOH, HYUNGJINreporter.nih.gov
Innovating anti-tuberculosis drug susceptibility testing with a novel and rapid non-culture based phenotypic test using MPT64 biomarkerNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,942,637April 4, 2023March 31, 2028KATO-MAEDA, MIDORIreporter.nih.gov
Identification of new inhibitors of essential functions in M. tuberculosis by high-throughput metabolic profilingNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,927,436November 18, 2022October 31, 2027BERNEY, MICHAELreporter.nih.gov
Parallel phenotyping to dissect genetic determinants of bacterial strain diversityNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,920,876August 9, 2022July 31, 2027CAREY, ALLISONreporter.nih.gov
The effect of inflammation and damage to lymph node structures on durable protective immunity following vaccinationNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,904,986February 25, 2019January 31, 2024SCHACKER, TIMOTHY Wreporter.nih.gov
Molecular Mechanisms of Transcription Initiation and DNA RepairNIHNational Institute of General Medical Sciences2022 to 2025$1,894,422March 1, 2022February 28, 2027GALBURT, ERIC Areporter.nih.gov
Eradicating persistent M. tuberculosis by synthetic lethality of terminal respiratory oxidasesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,893,366November 13, 2018October 31, 2025BERNEY, MICHAELreporter.nih.gov
Real-time tracking of virus evolution for vaccine strain selection and epidemiological investigationNIHNational Institute of General Medical Sciences2021 to 2025$1,886,759August 23, 2016May 31, 2026BEDFORD, TREVOR BCreporter.nih.gov
Targeting NETosis for the Treatment of TuberculosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,886,199June 1, 2023May 31, 2028STALLINGS, CHRISTINA LEIGHreporter.nih.gov
Role of mycobacterial dynamin-like proteins in the biogenesis of membrane vesicles, and host-pathogen interactionsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,878,234July 1, 2021June 30, 2027RODRIGUEZ, GLORIA MARCELAreporter.nih.gov
Heme and hemoglobin utilization by Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,878,218January 1, 2019December 31, 2024NIEDERWEIS, MICHAELreporter.nih.gov
Mechanisms and Consequences of Mycobacterial N-terminal Protein AcetylationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,878,000May 10, 2013August 31, 2025CHAMPION, PATRICIA Areporter.nih.gov
SAIA-TB: Using the Systems Analysis and Improvement Approach (SAIA) to prevent TB in rural South AfricaNIHNational Institute of Nursing Research2023 to 2025$1,875,237May 12, 2023February 29, 2028VAN DE WATER, BRITTNEY JAYNEreporter.nih.gov
Efficacy and Safety of AI-enabled PRS Regimen VI (Clofazimine, Bedaquiline and Pyrazinamide) as Ultra-Short Course Therapy of LTBI in Non-Human Primates in a setting mimicking HIV co-infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,866,727March 1, 2024January 31, 2027HORWITZ, MARCUS AARONreporter.nih.gov
New anti-tubercular agents targeting intracellular bacteriaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,866,467June 21, 2024January 31, 2026PARISH, TANYAreporter.nih.gov
The Effectiveness and Cost-Effectiveness of Implementing Evidence-Based Depression Treatment within the TB Care Platform in South Africa: A Hybrid Effectiveness-Implementation TrialNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,844,087September 1, 2025August 31, 2028SWEETLAND, ANNIKA CLAIREreporter.nih.gov
TB PuRe : Pulmonary rehabilitation to reduce post-tuberculosis morbidityNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,841,700September 1, 2023August 31, 2028GOLUB, JONATHAN E.reporter.nih.gov
Molecular mechanisms of host cell escape by Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,839,756January 10, 2019June 30, 2025BRIKEN, VOLKERreporter.nih.gov
Drifting to victory: resolving the paradox of M. tuberculosis evolutionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,839,296June 15, 2015May 31, 2026PEPPERELL, CAITLIN Sreporter.nih.gov
Automated lung sound analysis to improve the clinical diagnosis of pulmonary tuberculosis in childrenNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,836,717September 15, 2023August 31, 2028JAGANATH, DEVANreporter.nih.gov
Testing of Drug Combinations For Mycobacterium tuberculosis (MTB) in MiceNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,831,148September 1, 2022November 30, 2025SLAYDEN, RICHARDreporter.nih.gov
Personal Respiratory Isolation System for Safe Transport and Treatment of Patients with Highly Transmissible Infectious DiseasesNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,828,885September 18, 2024March 31, 2026KOTA, SRIDHARreporter.nih.gov
Maximizing Investigators' Research Award (R35)NIHNational Institute of General Medical Sciences2021 to 2025$1,821,876June 1, 2021May 31, 2026WHITE, LAURA FORSBERGreporter.nih.gov
Modulating Indoleamines to Optimize Immunity in the Setting of Mtb/HIV Co-infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,820,801June 21, 2024April 30, 2029MEHRA, SMRITIreporter.nih.gov
Molecular mechanisms of modular nuclease domainsNIHNational Institute of General Medical Sciences2021 to 2025$1,812,290September 15, 2021August 31, 2026MANHART, CAROL Mreporter.nih.gov
Functional exploration of a deep Mycobacterium tuberculosis phosphoproteomeNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,806,530February 3, 2023January 31, 2028GRUNDNER, CHRISTOPHreporter.nih.gov
Determining the performance and accuracy of SILVAMP TB LAM and cost-effectiveness of diagnostic testing for TB meningitisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,806,210June 21, 2022May 31, 2027BAHR, NATHANreporter.nih.gov
A dual function TB subunit vaccine designed for non-interference with BCG and post-exposure activityNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,803,446December 1, 2017November 30, 2023MORTENSEN, RASMUS SKAARUPreporter.nih.gov
Targeting trained immunity and Th1/Th17 axis with combination adjuvantsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,799,999July 26, 2021April 30, 2027KHADER, SHABAANA A.reporter.nih.gov
Enhancing Pediatric Diagnosis of Tuberculosis with FLOW TechnologyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2024$1,781,357May 10, 2022November 30, 2024MULLINS, BRIANNAreporter.nih.gov
Understanding the functional role of Myeloid Derived Suppressor cells in tuberculosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$1,779,708July 6, 2020June 30, 2025KHADER, SHABAANA A.reporter.nih.gov
Harnessing potent next-generation diarylquinolines for long-acting injectable formulations to prevent and treat tuberculosisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,778,326June 25, 2021June 30, 2027NUERMBERGER, ERIC Lreporter.nih.gov
Multivalent DNA vaccine-mediated protection against TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,773,692November 23, 2017October 31, 2024WEINER, DAVID B.reporter.nih.gov
A micronized electrostatic precipitator for next-generation respiratory protection against pathogenic aerosolsNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$1,772,894August 17, 2023July 31, 2025HENLEY, JULIANreporter.nih.gov
Type I IFN-dependent and independent contributions to the outcomes of early innate immune cell interactions during HIV/TB co-infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,772,038July 3, 2024June 30, 2029STALLINGS, CHRISTINA LEIGHreporter.nih.gov
Harnessing activated CD4 T cells to define new mechanisms of protection in tuberculosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,770,744July 1, 2023June 30, 2028BOLD, TYLER DALLASreporter.nih.gov
Innovative contact tracing strategies for detecting TB in mobile rural and urban South African populationsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,765,691August 7, 2019July 31, 2025DOWDY, DAVID WESLEYreporter.nih.gov
Role of IL-17 Cytokine Networks in TB Relapse Due to HIVNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,765,428June 21, 2019May 31, 2025ENDSLEY, JANICE Jreporter.nih.gov
Transporter function of the Mycobacterium tuberculosis PE/PPE proteinsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,765,004February 6, 2024December 31, 2028GRUNDNER, CHRISTOPHreporter.nih.gov
Targeting protein secretion in Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,763,806March 1, 2024January 31, 2026PARISH, TANYAreporter.nih.gov
Optimizing vaccine science to improve the outcome of tuberculosis treatmentNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,751,227June 17, 2021May 31, 2027SUBBIAN, SELVAKUMARreporter.nih.gov
Alternative Ribosomes & Antibiotic Tolerance in MycobacteriaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,747,655June 1, 2017July 31, 2028OJHA, ANIL KUMARreporter.nih.gov
SigH based attenuated, efficacious Mtb vaccines to protect against lethal TBNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,745,052May 17, 2018April 30, 2025KAUSHAL, DEEPAKreporter.nih.gov
Mycobacterium tuberculosis environmental signal integration: single cell in vivo understanding of its influence on infection heterogeneity and treatment efficacyNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,740,661September 18, 2019August 31, 2025TAN, SHUMINreporter.nih.gov
Understanding and addressing geographic barriers to accessing TB services in a high-burden urban settingNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,737,469February 1, 2023January 31, 2028JENKINS, HELEN E.reporter.nih.gov
Immune and metabolic dysfunction during aging in human cohortsNIHNational Institute on Aging2022 to 2024$1,732,734September 30, 2022May 31, 2026RESTREPO, BLANCA Ireporter.nih.gov
Mitochondria as crucial regulators of innate immune outcomes during Mycobacterium tuberculosis infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,731,677June 10, 2021July 31, 2024WATSON, ROBERT OWENreporter.nih.gov
Immune correlates of LTBI in HIV-exposed infantsNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,724,753January 5, 2019December 31, 2025PAHWA, SAVITAreporter.nih.gov
Harnessing potent next-generation diarylquinolines for long-acting injectable formulations to prevent and treat tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,723,189June 25, 2021May 31, 2024NUERMBERGER, ERIC Lreporter.nih.gov
Biomimetic Peptide Aerosols for Rapid Clearance of Pulmonary MDR TuberculosisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,718,155November 19, 2021October 31, 2026MEDINA, SCOTT HAMMONDreporter.nih.gov
Enhanced POC assay for TB in HIV-infected children based on the ultrasensitive detection of the urinary form of the lipoarabinomannan antigenNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,715,089April 14, 2020March 31, 2025PINTER, ABRAHAMreporter.nih.gov
Understanding ischemia in children with tuberculous meningitis (iThemba)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$1,692,676August 1, 2022May 31, 2027SEDDON, JAMES ALEXANDERreporter.nih.gov
The Rv2623-Rv1747 interaction: regulation of the in vivo fate of M. tuberculosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,687,352January 16, 2020December 31, 2026CHAN, JOHN R.reporter.nih.gov
Siyakhula: Growing HIV/TB Research Knowledge for Growing Healthy Kids in EswatiniNIHFogarty International Center2021 to 2025$1,686,671July 12, 2021March 31, 2027MANDALAKAS, ANNA Mreporter.nih.gov
Development of a Rapid Phenotypic Pyrazinamide Susceptibility Testing for Mycobacterium tuberculosis Using Well-Standardized ProtocolNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,684,821January 2, 2024December 31, 2026SHI, WANLIANGreporter.nih.gov
A Novel Th17-inducing Mucosal Vaccine for TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,676,215September 9, 2020September 2, 2022KHADER, SHABAANA A.reporter.nih.gov
Evaluating the Role of L,D-Transpeptidases in Mycobacterial PathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,659,285June 18, 2020November 30, 2026BEATTY, KIMBERLY ELIZABETHreporter.nih.gov
Short-course rifapentine for TB prevention for all: clinical pharmacology mattersNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,657,415August 7, 2024June 30, 2029DOOLEY, KELLY E.reporter.nih.gov
Molecular basis of antibiotic resilience in Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,656,213June 1, 2024April 30, 2029FORTUNE, SARAHreporter.nih.gov
"The molecular mechanisms of asymmetric cell division in mycobacteria."NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,655,369May 12, 2020April 30, 2025REGO, ELIZABETH HESPERreporter.nih.gov
Perceived Laws and Infectious Disease Control MeasuresNIHNational Institute of Nursing Research2023 to 2025$1,648,078August 23, 2023May 31, 2028GALLETLY, CAROL Lreporter.nih.gov
RNA Vaccine Innovations for TB: Targeting the MucosaNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,632,094April 22, 2022September 30, 2025REED, STEVEN GREGORYreporter.nih.gov
The role of lymphatic clearance in brain TBNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,623,071May 15, 2022April 30, 2027SANDOR, MATYASreporter.nih.gov
Advancing Innovative Next_generation Heterologous Vaccines Against TuberculosisNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,615,572May 10, 2022April 30, 2026BEAMER, GILLIAN Lreporter.nih.gov
Investigating (di)terpenoid biosynthesisNIHNational Institute of General Medical Sciences2021 to 2023$1,611,459June 1, 2019November 30, 2024PETERS, REUBEN JOHNreporter.nih.gov
Air Pollution Effects on Transmission of Mycobacterium tuberculosis in Urban Slum Community in UgandaNIHNational Institute of Environmental Health Sciences2022 to 2025$1,606,414September 15, 2012June 30, 2028SCHWANDER, STEPHAN Kreporter.nih.gov
Inhalational therapy with spectinamides within new regimens of TB therapyNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,605,491July 5, 2024June 30, 2029GONZALEZ-JUARRERO, MERCEDESreporter.nih.gov
A novel protein export chaperone of Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,598,834January 3, 2020August 31, 2023BRAUNSTEIN, MIRIAM S.reporter.nih.gov
TB/MDR-TB Research training and Capacity Strengthening for LMIC in Southeast Asia Phase IINIHFogarty International Center2021 to 2025$1,596,256May 1, 2015February 28, 2027CHONGSUVIVATWONG, VIRASAKDIreporter.nih.gov
The Role of Casual Contact and Migration in XDR TB Transmission in South Africa: a Geospatial, Genomic and Social Network StudyNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,594,622January 17, 2018December 31, 2024SHAH, NIPPIE SARITAreporter.nih.gov
Understanding the functional role of Myeloid Derived Suppressor cells in tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,589,530July 6, 2020September 2, 2022KHADER, SHABAANA A.reporter.nih.gov
Target based discovery of next generation pyrazinamideNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,586,105August 1, 2013May 31, 2023DICK, THOMASreporter.nih.gov
Type II alveolar epithelial cell-intrinsic IL-1 response in protective immunity against tuberculosisNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,576,457June 1, 2023May 31, 2027MISHRA, BIBHUTI BHUSANreporter.nih.gov
Foam cells as drug targets in tuberculosisNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,575,009August 1, 2019June 30, 2025GENNARO, MARIA LAURAreporter.nih.gov
Mechanisms of IFNg-independent T cell and B cell-mediated protection in TB.NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,569,789August 26, 2024June 30, 2029SALGAME, PADMINIreporter.nih.gov
Synthetic Macrophage-inducible C-type lectin (Mincle) Agonists: Screening, Design, and Formulation in combination Th17 adjuvantsNIHNational Institute of Allergy and Infectious Diseases2024$1,563,776September 30, 2024September 29, 2029reporter.nih.gov
Point of care detection of fluroquinolone, bedaquiline and linezolid resistant Mycobacterium tuberculosis for rapid treatment decisions.NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,555,676February 26, 2024December 31, 2028ALLAND, DAVIDreporter.nih.gov
Control of cell wall synthesis and antibiotic tolerance in mycobacteriaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,552,748June 1, 2020May 31, 2026BOUTTE, CARA CHENEYreporter.nih.gov
Characterization of Genomics and Metabolomics among Individuals Highly-Exposed, but resistant to Mtb InfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,552,036July 1, 2018June 30, 2025GANDHI, NEEL RAJNIKANTreporter.nih.gov
C-type Lectin Receptor Pathways in the Pathogenesis of TB/HIV Co-infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,551,336April 1, 2018April 30, 2025ENDSLEY, JANICE Jreporter.nih.gov
Metabolic regulation of macrophage function during M. tuberculosis infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,550,855April 10, 2015May 31, 2026STANLEY, SARAH Areporter.nih.gov
Structure and function of ClpXPNIHNational Institute of General Medical Sciences2021 to 2024$1,548,938April 1, 2021March 31, 2026SAUER, ROBERT Treporter.nih.gov
Understanding early macrophage-T cell interactions, SLAMF1, and immunity to TBNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,544,840July 1, 2024June 30, 2029PHILIPS, JENNIFER Areporter.nih.gov
Trial of Metformin for TB/HIV Host-directed TherapyNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,542,974May 15, 2019April 30, 2026KORNFELD, HARDYreporter.nih.gov
Development of 1,2,4-Triazolyl Compounds and their derivatives as a New Treatment for TuberculosisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,532,717August 1, 2024July 31, 2029STALLINGS, CHRISTINA LEIGHreporter.nih.gov
Development of Novel Proteins Synthesis Inhibitors for MDR TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,526,635July 6, 2010February 29, 2024LEE, RICHARD E.reporter.nih.gov
Design and characterization of biomimetic nanobiomaterials to elicit CD1-restricted T cell responses during sub-unit vaccinationNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,522,818August 1, 2019July 31, 2025SCOTT, EVAN ALEXANDERreporter.nih.gov
Role of mycobacterial dynamin-like proteins in the biogenesis of membrane vesicles, and host-pathogen interactionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,521,407July 1, 2021June 30, 2026RODRIGUEZ, GLORIA MARCELAreporter.nih.gov
Determining the role of sphingolipids in Mycobacterium tuberculosis infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,520,395December 1, 2019November 30, 2025TAFESSE, FIKADU G.reporter.nih.gov
Development of Drugs to Target Arginine Biosythesis in Mycobacterium tuberculosisNIHNational Institute of General Medical Sciences2021 to 2024$1,510,000April 22, 2021March 31, 2026TIWARI, SANGEETAreporter.nih.gov
The PDIM paradox of M. tuberculosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,505,403February 1, 2023January 31, 2028BERNEY, MICHAELreporter.nih.gov
Development of novel penems for drug-resistant tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,504,818January 3, 2018December 31, 2024TOWNSEND, CRAIG ARTHURreporter.nih.gov
Ontogeny and metabolism of lung alveolar macrophages in tuberculosisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,503,349August 13, 2024July 31, 2029HUANG, LUreporter.nih.gov
RAPID POINT OF CARE TESTS FOR TUBERCULOSISNIHNational Institute of Allergy and Infectious Diseases2021$1,500,000August 12, 2021August 8, 2024ZHOU, YANreporter.nih.gov
INNOVATIVE PEDIATRIC ORAL FORMULATIONS FOR SECOND LINE TUBERCULOSIS DRUGSNIHNational Institute of Allergy and Infectious Diseases2021$1,499,998September 3, 2021BRAUN, NIKOLAIreporter.nih.gov
Siderophore Inhibitors for Tuberculosis that Block Mycobactin BiosynthesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,499,516April 25, 2018March 31, 2023ALDRICH, COURTNEY Creporter.nih.gov
Host-directed therapy of tuberculosis: Rescuing macrophages and enhancing their activationNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,495,330September 24, 2018August 31, 2023NATHAN, CARL FRANCISreporter.nih.gov
HIV-associated Tuberculosis Training Program (HATTP)NIHFogarty International Center2021 to 2025$1,494,206September 11, 2017April 30, 2027MEINTJES, GRAEME AYTONreporter.nih.gov
Development of a highly-multiplexed CRISPR-based TB drug susceptibility testNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,493,529June 24, 2024May 31, 2029XIE, YINGDA LINDAreporter.nih.gov
Ethiopia-Emory TB Research Training ProgramNIHFogarty International Center2021 to 2025$1,483,720July 2, 2013December 31, 2028BLUMBERG, HENRY Mreporter.nih.gov
Enhanced POC assay for TB in HIV-infected children based on the ultrasensitive detection of the urinary form of the lipoarabinomannan antigenNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$1,480,554April 14, 2020March 31, 2026PINTER, ABRAHAMreporter.nih.gov
Impact of TB coinfection on HIV reservoirNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,471,070December 11, 2023October 31, 2028DUPNIK, KATHRYN Mreporter.nih.gov
Identifying individuals at risk of progression to active tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,471,016February 22, 2018January 31, 2025CATANZARO, ANTONINOreporter.nih.gov
Novel next-generation sequencing assay for monitoring multidrug resistant tuberculosis treatment in the setting of HIV infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,468,336January 19, 2018December 31, 2023METCALFE, JOHN ZAPATAreporter.nih.gov
Phase II: Development of Low-Cost, Shelf-Stable Treatment for TuberculosisNIHNational Institute of Allergy and Infectious Diseases2023$1,468,122September 15, 2023September 14, 2026WARNKEN, ZACHARYreporter.nih.gov
Precision immunoprofiling to reveal diagnostic biomarkers of latent TB infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,466,090September 5, 2019August 31, 2025BAILEY, RYAN Creporter.nih.gov
Immunometabolic Biomarkers to Advance TB Diagnosis and Treatment MonitoringNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,465,214April 16, 2024February 28, 2029COLLINS, JEFFREY Mreporter.nih.gov
Ultrasensitive detection of Mycobacterium tuberculosis infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,461,934July 22, 2024June 30, 2029CIRILLO, JEFFREY D.reporter.nih.gov
Understanding How the Ubiquitin Ligase CBL Regulates Innate Immune ResponsesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,457,172September 19, 2019August 31, 2024PENN, BENNETTreporter.nih.gov
Re-evaluating the Duration in Children of TB Treatment (REDUCE TB): A Phase 2 Duration Randomized TrialNIHNational Institute of Allergy and Infectious Diseases2025$1,450,790September 19, 2025August 31, 2030GARCIA-PRATS, ANTHONY JOSEPHreporter.nih.gov
Dissecting the genetic basis of protective immunity to tuberculosis in diverse hostsNIHNational Institute of General Medical Sciences2021$1,449,000September 20, 2021August 31, 2024SMITH, CLARE MARGARETreporter.nih.gov
CRISPR-TB for pediatric TB diagnosis and treatment responseNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,446,304July 11, 2024May 31, 2029LACOURSE, SYLVIAreporter.nih.gov
Tuberculosis & HIV Co-Infection Training Program in KenyaNIHFogarty International Center2021 to 2025$1,438,418May 1, 2021March 31, 2027HAWN, THOMAS Rreporter.nih.gov
Interleukin-6 signaling, lung injury, and post-TB lung disease in TB-HIVNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,430,251September 1, 2025August 31, 2029GUPTE, AKSHAY NITINreporter.nih.gov
Targeting mediators of oxidative stress to limit hyperinflammatory cell death modalities during Mycobacterium tuberculosis infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,429,810June 24, 2024April 30, 2029WATSON, ROBERT OWENreporter.nih.gov
Novel Nanoparticle Respiratory Tract Mucosal VaccineNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,426,482April 1, 2022March 31, 2025QUINN, FREDERICK Dreporter.nih.gov
Autophagy proteins in the immune response to Mycobacterium tuberculosis infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,426,352November 7, 2018October 31, 2024STALLINGS, CHRISTINA LEIGHreporter.nih.gov
Evolution, transmission, and control of drug-resistant tuberculosisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,424,054July 17, 2024May 31, 2029GRUBAUGH, NATHAN DALEreporter.nih.gov
Using Single Cell Biological Approaches to Understand CNS TBNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,419,875August 15, 2023May 31, 2029DULLA, CHRIS Greporter.nih.gov
Quantifiable stool-based TB PCR to Improve Diagnostics and Treatment MonitoringNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,418,806July 1, 2019June 30, 2024MANDALAKAS, ANNA Mreporter.nih.gov
Interaction of Mycobacterium tuberculosis with upper airway mucosal cellsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,414,352June 10, 2024May 31, 2029SHILOH, MICHAELreporter.nih.gov
Optimizing vaccine science to improve the outcome of tuberculosis treatmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,409,583June 17, 2021May 31, 2023SUBBIAN, SELVAKUMARreporter.nih.gov
Regulation of CD8+ T cell immunity to tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,409,160August 2, 2013April 30, 2024BEHAR, SAMUEL Mreporter.nih.gov
Investigating the role of liquid-liquid phase separation in the interaction between Mycobacterium tuberculosis and macrophagesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,398,216August 10, 2021July 31, 2026BELL, SAMANTHA LYNNreporter.nih.gov
Target and Non-target Based Resistance to Bedaquiline in South AfricaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,396,710April 20, 2020March 31, 2025MAKHADO, NDIVHUreporter.nih.gov
Developing a Multivalent Subunit Particle Vaccine Against TuberculosisNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,392,562April 1, 2022March 31, 2025LOVELL, JONATHAN Freporter.nih.gov
Innate immune response of LTBI+HIV+ childrenNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,390,281September 14, 2020February 18, 2024VANKAYALAPATI, RAMAKRISHNAreporter.nih.gov
Rip1 controlled stress resistance and virulence in Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,389,906February 7, 2019January 31, 2024GLICKMAN, MICHAEL Sreporter.nih.gov
Nanoreactor beads for POC TB resistance testingNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,388,246November 7, 2023October 31, 2028ALLAND, DAVIDreporter.nih.gov
Impact of HIV on the human alveolar environment drivingthe early events of Mycobacterium tuberculosis infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,384,896August 16, 2024August 8, 2025TORRELLES, JORDI Breporter.nih.gov
Structural characterization of MCE transport systems from Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,384,410February 3, 2023January 31, 2028BHABHA, GIRAreporter.nih.gov
TB PrEP - Integrating HIV prevention with TB household contact evaluationNIHNational Institute of Mental Health2024 to 2025$1,383,983September 9, 2024August 31, 2029ROSS, JENNIFER Mreporter.nih.gov
Molecular Genetic Analysis of Mycobacterium TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,383,455December 1, 1988August 31, 2023JACOBS, WILLIAM ROBERTreporter.nih.gov
When are in-person HIV services worth the risk of COVID-19 and other communicable illnesses? Optimizing choices when virtual services are less effectiveNIHNational Institute of Mental Health2025$1,375,435September 1, 2022July 31, 2027BERSHTEYN, ANNAreporter.nih.gov
A novel hyper-immunogenic low virulent BCG vaccine against tuberculosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,373,187February 3, 2023April 20, 2025DHANDAYUTHAPANI, SUBRAMANIANreporter.nih.gov
How Mtb 3B-hydroxysteroid dehydrogenase accesses host cholesterolNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,367,738February 13, 2024December 31, 2028PHILIPS, JENNIFER Areporter.nih.gov
High-throughput identification of common CD8+ T cell responses to SIV and M. tuberculosis in rhesus macaquesNIHOffice of the Director, National Institutes of Health2021 to 2022$1,362,096September 1, 2014January 31, 2025O'CONNOR, DAVID H.reporter.nih.gov
Addressing Research Gaps to Optimize Dolutegravir-based ART in Children and AdolescentsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,358,823August 5, 2024June 30, 2029KWARA, AWEWURA JACOBreporter.nih.gov
Lung Resident, MR1-Restricted T Cells: Association with Differential Outcomes Following Exposure to M. TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,355,786June 15, 2018May 31, 2024LEWINSOHN, DAVID M.reporter.nih.gov
Development of Novel mRNA Vaccines Against Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,336,253May 20, 2022March 31, 2025POSTLER, THOMAS SIEGMUNDreporter.nih.gov
Imaging signatures of early tuberculosisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,324,897November 9, 2023October 31, 2028XIE, YINGDA LINDAreporter.nih.gov
A Rapid Phenotypic Drug Susceptibility Testing System for TuberculosisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,312,786August 23, 2024June 30, 2029KAMARIZA, MIREILLEreporter.nih.gov
Mathematical modeling of Mycobacterium tuberculosis disseminationNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,312,263April 22, 2022March 31, 2027GANUSOV, VITALY V.reporter.nih.gov
Improving outcomes in HIV-associated opportunistic infections using CNS pharmacokinetics and pharmacodynamicsNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,308,986August 18, 2024May 31, 2029NICOL, MELANIE RAEreporter.nih.gov
Research Training Program in Adolescent HIV in HaitiNIHFogarty International Center2021 to 2024$1,305,920April 22, 2020December 31, 2025PAPE, JEAN WILLIAMreporter.nih.gov
Immune-mediated adverse drug reactions to HIV and TB treatments in South Africa: predict, prevent and improve long-term outcomes (IMARI SA study)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,298,050April 21, 2020March 31, 2026MEINTJES, GRAEME AYTONreporter.nih.gov
Lung Ultrasound and Artificial Intelligence Technology for the Diagnosis of TB in LMICsNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,295,946February 15, 2024January 31, 2029GILMAN, ROBERT Hreporter.nih.gov
3STEP: A swab-seal-read assay for tuberculosis and RIF resistance enabled by autonomous extraction technologyNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,295,893July 3, 2025June 30, 2027WARRICK, JAY WYATTreporter.nih.gov
Novel nanoparticular diagnostics for cerebral toxoplasmosis and Chagas in HIV patients living in Latin AmericaNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,293,572June 18, 2018May 31, 2024GILMAN, ROBERT Hreporter.nih.gov
Nanoparticle-based host-directed therapies for eradication of Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,286,699April 6, 2020March 31, 2026SAMPSON, SAMANTHA LEIGHreporter.nih.gov
Predicting tuberculosis outcomes using genotypic and biomarker signaturesNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,282,364January 15, 2019June 14, 2022BEAMER, GILLIAN Lreporter.nih.gov
TB-TST (TB treatment support tools): Refinement and evaluation of an interactive mobile app and direct adherence monitoring on TB treatment outcomesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,281,081June 19, 2019May 31, 2025RUBINSTEIN, FERNANDO ADRIÁNreporter.nih.gov
METABOLIC REPROGRAMMING OF T CELL ENERGY METABOLISM IN TUBERCULOSIS AND HIVNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,272,723April 1, 2018March 31, 2025STEYN, ADRIE JCreporter.nih.gov
Defining drivers of TB transmission in the era of universal ART, and implications for finding the walking wellNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,271,880August 8, 2019July 31, 2025GRANT, ALISONreporter.nih.gov
Optimal tuberculosis screening and tuberculosis preventive therapy delivery strategies to improve maternal and birth outcomes among pregnant women with HIV in Uganda: a randomized trialNIHNational Heart, Lung, and Blood Institute2025$1,265,657September 20, 2025August 31, 2026YOON, CHRISTINAreporter.nih.gov
TB detection in children using a novel stool-based GeneXpert assayNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,264,372December 5, 2017November 30, 2023ALLAND, DAVIDreporter.nih.gov
BCG overexpressing a small molecule STING agonist as a vaccine for TBNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,261,288June 20, 2024July 31, 2028WALLACH, TODDreporter.nih.gov
Evaluating the tuberculosis epidemic in South Africa using a novel ten-year cohortNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,258,516April 13, 2020March 31, 2026SCOTT, LESLEYreporter.nih.gov
Peer-led Implementation of TB-HIV Education and Adherence Counseling in UgandaNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,256,909September 5, 2024June 30, 2029DAVIS, JOHN LUCIANreporter.nih.gov
M. tuberculosis metabolites to activate human mucosal-associated invariant T cellsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,256,392June 1, 2023May 31, 2028HUANG, SHOUXIONGreporter.nih.gov
Estimation of risk associated with zoonotic tuberculosis in South IndiaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,255,278February 20, 2024December 31, 2028KAPUR, VIVEKreporter.nih.gov
Structural and Functional Characterization of RNA polymerase and its Regulators from Mycobacterium tuberculosis and Clostridioides difficileNIHNational Institute of General Medical Sciences2021 to 2023$1,247,663April 1, 2015May 31, 2024CAMPBELL, ELIZABETH Areporter.nih.gov
Transcriptome and proteome remodeling by Mycobacterium tuberculosis MazF toxinsNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$1,239,566December 1, 2019November 30, 2025WOYCHIK, NANCY ANNreporter.nih.gov
Options for Delivery of Short-Course Tuberculosis Preventive Therapy: The 3HP Options TrialNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,236,357August 1, 2018July 31, 2030CATTAMANCHI, ADITHYAreporter.nih.gov
Pharmacokinetics of Anti-tuberculosis and Antiretroviral Drugs in ChildrenNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$1,231,172July 15, 2012August 31, 2025KWARA, AWEWURA JACOBreporter.nih.gov
Heart and Lung Outcomes Post-TB (HALO Post-TB)NIHNational Heart, Lung, and Blood Institute2024 to 2025$1,226,165September 25, 2024June 30, 2029HSUE, PRISCILLA Y.reporter.nih.gov
Flow Direct: Next Generation Urine LFA for TB Diagnosis in Point-of-Care SettingsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,216,195September 19, 2025August 31, 2027WARRICK, JAY WYATTreporter.nih.gov
Transcriptome and proteome remodeling by Mycobacterium tuberculosis MazF toxinsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,215,943December 1, 2019November 30, 2022WOYCHIK, NANCY ANNreporter.nih.gov
Building the Next Generation of Researchers in TB/HIV Diagnostics in Mali (B-NextGen)NIHFogarty International Center2021 to 2024$1,203,194April 9, 2016March 31, 2026MURPHY, ROBERT LEOreporter.nih.gov
Interplay between the Mtb electron transport chain and carbon metabolismNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,197,306November 7, 2018October 31, 2024STEYN, ADRIE JCreporter.nih.gov
THWART-TB : Testing Health Workers At Risk to advance our understanding of TB infectionNIHNational Institute of Allergy and Infectious Diseases2023$1,189,520February 16, 2023January 31, 2026NATHAVITHARANA, RUVANDHIreporter.nih.gov
Regulation of Immune Responses to Mycobacterium tuberculosis InfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,188,492September 24, 2018August 31, 2024STALLINGS, CHRISTINA LEIGHreporter.nih.gov
Studies of lipoamide dehydrogenase tight binding inhibition in tuberculous and non-tuberculous mycobacteriaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,188,030November 22, 2023October 31, 2028BRYK, RUSLANAreporter.nih.gov
Emory-Georgia TB Research Training ProgramNIHFogarty International Center2022 to 2025$1,187,449September 27, 2004February 28, 2027BLUMBERG, HENRY Mreporter.nih.gov
The role of non-classical MHC class I molecules in immune responses to Mycobacterium tuberculosis infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,184,815May 14, 2018April 30, 2025WANG, CHYUNG-RUreporter.nih.gov
Infectiousness and social mixing in asymptomatic TB as a driver of population-level transmissionNIHNational Institute of Allergy and Infectious Diseases2025$1,173,748September 16, 2025August 31, 2030SHAH, NIPPIE SARITAreporter.nih.gov
Targeting trained immunity and Th1/Th17 axis with combination adjuvantsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,167,749July 26, 2021September 1, 2022KHADER, SHABAANA A.reporter.nih.gov
Pathogen and host predictors of M. tuberculosis transmissionNIHNational Institute of Allergy and Infectious Diseases2025$1,166,933September 3, 2025August 31, 2030STERLING, TIMOTHY Rreporter.nih.gov
Testing of a Novel Inhaled Clofazimine (CFZ) Dry Powder Formulation in a Mouse Model of Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,164,080August 1, 2023June 30, 2025ENDSLEY, JANICEreporter.nih.gov
Mathematical modeling of Mycobacterium tuberculosis disseminationNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$1,162,376April 22, 2022July 31, 2023GANUSOV, VITALY V.reporter.nih.gov
Oral BCG: Optimizing mucosal vaccination against tuberculosisNIHNational Institute of Allergy and Infectious Diseases2025$1,162,224April 24, 2025March 31, 2030LIN, PHILANA LINGreporter.nih.gov
Mitochondria as crucial regulators of innate immune outcomes during Mycobacterium tuberculosis infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,157,211June 10, 2021May 31, 2027WATSON, ROBERT OWENreporter.nih.gov
2/1 - Mongolian Center for Environmental & Occupational Health - MongoliaNIHFogarty International Center2022 to 2025$1,156,208June 13, 2022February 28, 2027DAMBADARJAA, DAVAALKHAM -reporter.nih.gov
Investigating the role of liquid-liquid phase separation in the interaction between Mycobacterium tuberculosis and macrophagesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,152,144August 10, 2021July 31, 2026BELL, SAMANTHA LYNNreporter.nih.gov
Developing research leaders at the intersection of malnutrition and tuberculosis in TanzaniaNIHFogarty International Center2022 to 2025$1,145,152March 1, 2022February 28, 2027HEYSELL, SCOTT Kreporter.nih.gov
Disrupting Tuberculosis Transmission: Bacterial and Host Drivers of Mycobacterium Tuberculosis AerosolizationNIHNational Institute of Allergy and Infectious Diseases2025$1,141,359September 11, 2025August 31, 2030SHILOH, MICHAELreporter.nih.gov
PREVINE-TB: PRevent: EValuating the implementation of NEw strategies for preventive TB among people living with HIV in BrazilNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,140,930July 1, 2018June 30, 2025GOLUB, JONATHAN E.reporter.nih.gov
The role of nanocompartments in M. tuberculosis pathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,139,634September 18, 2019August 31, 2025STANLEY, SARAH Areporter.nih.gov
Post-Tuberculosis Lung Disease in Youth with and without HIV GloballyNIHNational Institute of Allergy and Infectious Diseases2025$1,136,143August 22, 2025July 31, 2030ENANE, LESLIE ANNEreporter.nih.gov
Dynamic allosteric communication within nonribosomal peptide synthetase cyclization domainsNIHNational Institute of General Medical Sciences2021 to 2023$1,135,905June 1, 2013February 28, 2025FRUEH, DOMINIQUE PASCALreporter.nih.gov
Memory, Phenotype, and Function of TB-reactive Human MR1 Restricted T cellsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,133,140February 1, 2019January 31, 2024LEWINSOHN, DAVID M.reporter.nih.gov
High Dose Oral Rifampicin to Improve Survival from Adult Tuberculous Meningitis: a pharmacokinetic substudy (HARVEST-PK)NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,122,044January 22, 2024November 30, 2028TE BRAKE, LINDSEYreporter.nih.gov
Theory and Modeling of Functional Conformational Changes of RNA PolymerasesNIHNational Institute of General Medical Sciences2023 to 2025$1,120,475June 1, 2023May 31, 2028HUANG, XUHUIreporter.nih.gov
Wastewater surveillance to enhance the public health response to HIV and TB in EswatiniNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$1,120,000September 1, 2024July 31, 2029KAY, ALEXANDER WILLIAMreporter.nih.gov
Conditional Expression of Mycobacterial GenesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,094,554February 15, 2006August 31, 2024EHRT, SABINEreporter.nih.gov
Immunoregulation by indoleamine 2,3-dioxygenases in tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,083,318May 1, 2018April 30, 2024CHAN, JOHN R.reporter.nih.gov
New targets against tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021$1,076,804July 1, 2017June 30, 2023HUNG, DEBORAH Treporter.nih.gov
Development of a novel adjuvanted Th1- and Th17-inducing subunit TB VaccineNIHNational Institute of Allergy and Infectious Diseases2025$1,067,980March 1, 2023August 31, 2027KHADER, SHABAANA A.reporter.nih.gov
The Bacterial Genetic Basis of Bone Disease and Dissemination in Mycobacterial Infection: Roles of ESX-5 Secreted WXG EffectorsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,056,566August 15, 2017October 31, 2028TOBIN, DAVID M.reporter.nih.gov
Khulani Siphile Siphuhle Training Program in South Africa (KiSS-TP)NIHFogarty International Center2023 to 2025$1,042,352April 1, 2023March 31, 2029MEDINA-MARINO, ANDREWreporter.nih.gov
Host-bacterial interactions determining the spectrum of Mtb transmissionNIHNational Institute of Allergy and Infectious Diseases2025$1,041,944September 11, 2025August 31, 2030SALGAME, PADMINIreporter.nih.gov
Transmission Links and Clinical Spectrum of Exhaled Mycobacterium TuberculosisNIHNational Institute of Allergy and Infectious Diseases2025$1,032,233September 10, 2025August 31, 2030XIE, YINGDA LINDAreporter.nih.gov
The Rv2623-Rv1747 interaction: regulation of the in vivo fate of M. tuberculosisNIHNational Institute of Allergy and Infectious Diseases2022$1,020,438January 16, 2020December 31, 2022CHAN, JOHN R.reporter.nih.gov
Understanding HIV's impact on RR/MDR-TB development and transmission through genomicsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,012,877June 1, 2025May 31, 2027BOUTON, TARA CATHERINEreporter.nih.gov
Determinants of antigen specific CD4 T cell function in tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,006,392April 1, 2021September 30, 2026BOLD, TYLER DALLASreporter.nih.gov
Digital adherence technologies to facilitate completion of short-course tuberculosis preventive therapy among people living with HIVNIHNational Heart, Lung, and Blood Institute2021 to 2025$1,005,750September 8, 2021August 31, 2026BERGER, CHRISTOPHER ALLENreporter.nih.gov
TOLLIP Deficiency, Immune Dysregulation, and Tuberculosis SusceptibilityNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,003,164March 1, 2018February 29, 2024SHAH, JAVEED ALIreporter.nih.gov
Feasibility and acceptability of a peer-led strategy to improve community tuberculosis case finding among non-household contacts in ZambiaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$999,000July 15, 2021June 30, 2026KERKHOFF, ANDREWreporter.nih.gov
Bacterial Cell Wall Composition and the Influence of AntibioticsNIHNational Institute of General Medical Sciences2021 to 2023$997,488September 1, 2016May 31, 2025CEGELSKI, LYNETTE Sreporter.nih.gov
Novel Spectinamide Antibiotics for the Treatment of MDR/XDR TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021$996,798August 1, 2012July 31, 2024BUTLER, MICHELLE M.reporter.nih.gov
The Transmission Biology of Mycobacterium TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$974,300June 22, 2021May 31, 2027BROWN, CHRISTOPHER DAVIDreporter.nih.gov
Live nasal recombinant B. pertussis vaccine against tuberculosisNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$972,074May 4, 2022March 31, 2026GOLDSTEIN, PETERreporter.nih.gov
Mechanisms of Viral PersistenceNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$972,000December 1, 2009June 30, 2025BROOKS, DAVID Greporter.nih.gov
Nitrosative stress and NO detoxifying reaction mechanisms in microbial nonheme diiron proteinsNIHNational Institute of General Medical Sciences2023 to 2025$970,200April 1, 2023February 28, 2027MOENNE-LOCCOZ, PIERREreporter.nih.gov
Dissecting the genetic basis of protective immunity to tuberculosis in diverse hostsNIHNational Institute of Allergy and Infectious Diseases2024$966,000September 20, 2021August 31, 2026SMITH, CLARE MARGARETreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
University of California Los AngelesLos Angeles, CA13$588.3 million0$0
Fred Hutchinson Cancer CenterSeattle, WA5$431.4 million0$0
Harvard University D/b/a Harvard School of Public HealthBoston, MA11$196.9 million0$0
Johns Hopkins UniversityBaltimore, MD63$179.1 million0$0
University of California, San FranciscoSan Francisco, CA60$125.6 million0$0
Seattle Children's HospitalSeattle, WA20$117 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ36$62.4 million0$0
Emory UniversityAtlanta, GA29$55.5 million0$0
Vanderbilt University Medical CenterNashville, TN14$53.3 million0$0
Albert Einstein College of MedicineBronx, NY21$43.4 million0$0
Weill Medical Coll of Cornell UnivNew York, NY28$36.1 million0$0
University of WashingtonSeattle, WA31$36 million0$0
Rbhs-New Jersey Medical SchoolNewark, NJ26$35.1 million0$0
Washington UniversitySaint Louis, MO26$31.3 million0$0
University of MinnesotaMinneapolis, MN26$31.1 million0$0
Wits Health Consortium (pty), LTDParktown5$30.9 million0$0
University of California, San DiegoLa Jolla, CA11$30.6 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC6$29.7 million0$0
Brigham and Women's HospitalBoston, MA12$26.5 million0$0
Saint Louis UniversitySaint Louis, MO6$25.4 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA16$25.3 million0$0
Columbia University Health SciencesNew York, NY13$24.7 million0$0
University of MontanaMissoula, MT3$24.4 million0$0
Texas Biomedical Research InstituteSan Antonio, TX19$24 million0$0
University of Cape TownRondebosch10$23.8 million0$0
University of ChicagoChicago, IL13$23 million0$0
Stellenbosch UniversityStellenbosch15$21.2 million0$0
Case Western Reserve UniversityCleveland, OH6$19.4 million0$0
Indiana University IndianapolisIndianapolis, IN3$18.4 million0$0
Tulane University of LouisianaNew Orleans, LA8$18.3 million0$0
Universitat BernBern1$16.8 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA17$16.8 million0$0
Colorado State UniversityFort Collins, CO13$16.6 million0$0
Yale UniversityNew Haven, CT17$16 million0$0
Massachusetts General HospitalBoston, MA8$15.8 million0$0
Asociacion Civil Impacta Salud Y EducacnLima1$15.5 million0$0
La Jolla Institute for ImmunologyLa Jolla, CA2$15.4 million0$0
University of Wisconsin-MadisonMadison, WI9$14.5 million0$0
Centre/aids Programme/res/south AfricaDurban3$14.2 million0$0
Hackensack University Medical CenterHackensack, NJ5$14.2 million0$0
New York University School of MedicineNew York, NY6$13.5 million0$0
Oregon Health & Science UniversityPortland, OR15$13.4 million0$0
Boston Medical CenterBoston, MA7$12.6 million0$0
Ut Southwestern Medical CenterDallas, TX7$12.3 million0$0
Tufts University BostonBoston, MA12$12.2 million0$0
Duke UniversityDurham, NC15$11.9 million0$0
University of Alabama at BirminghamBirmingham, AL11$11.2 million0$0
University of California-IrvineIrvine, CA5$11.2 million0$0
University of VirginiaCharlottesville, VA10$11.1 million0$0
Boston University Medical CampusBoston, MA14$11 million0$0
University of SydneySydney1$11 million0$0
Gheskio CenterPort-Au-Prince2$11 million0$0
Methodist Hospital Research InstituteHouston, TX4$10.9 million0$0
American Type Culture CollectionManassas, VA1$10.7 million0$0
Northwestern University at ChicagoChicago, IL6$10.4 million0$0
Harvard Medical SchoolBoston, MA15$10.3 million0$0
Chiang Mai UniversityChiang Mai1$10.1 million0$0
Henry M. Jackson FDN for the Adv Mil/medBethesda, MD1$9.9 million0$0
Michigan State UniversityEast Lansing, MI8$9.8 million0$0
Midwest Research InstituteKansas City, MO3$8.7 million0$0
Public Health Foundation EnterprisesCity Of Industry, CA1$8.3 million0$0
Fundacao Oswaldo CruzRio de Janeiro1$8.2 million0$0
Cornell UniversityIthaca, NY7$7.8 million0$0
University of FloridaGainesville, FL6$7.7 million0$0
Stanford UniversityStanford, CA7$7.7 million0$0
Baylor College of MedicineHouston, TX6$7.6 million0$0
Aurum Institute NPCParktown, Johannesburg2$6.8 million0$0
University of Notre DameNotre Dame, IN7$6.5 million0$0
Desmond Tutu Health FoundationCape Town4$6.4 million0$0
Stichting Radboud Universitair Medisch Centrum I.o.Nijmegen3$5.8 million0$0
University of Texas Med BR GalvestonGalveston, TX5$5.8 million0$0
University of Georgia Research Foundation IncAthens, GA9$5.3 million0$0
Pennsylvania State Univ University ParkUniversity Park, PA3$5 million0$0
Texas A&m University Health Science CTRCollege Station, TX10$5 million0$0
University of New Mexico Health Scis CTRAlbuquerque, NM2$4.9 million0$0
University of Maryland, College ParkCollege Park, MD4$4.8 million0$0
PPD Development LPWilmington, NC1$4.7 million0$0
Rockefeller UniversityNew York, NY3$4.6 million0$0
Massachusetts Institute of TechnologyCambridge, MA5$4.6 million0$0
Beth Israel Deaconess Medical CenterBoston, MA4$4.6 million0$0
Institute for Systems BiologySeattle, WA1$4.4 million0$0
Wadsworth CenterMenands, NY5$4.4 million0$0
Salus Discovery, LLCMadison, WI3$4.3 million0$0
Fimbrion Therapeutics, Inc.Saint Louis, MO4$4.2 million0$0
SUNY at BuffaloAmherst, NY5$4.1 million0$0
Sloan-Kettering Inst Can ResearchNew York, NY2$4 million0$0
University of Michigan at Ann ArborAnn Arbor, MI2$4 million0$0
Boston Children's HospitalBoston, MA5$3.9 million0$0
University of California-Santa CruzSanta Cruz, CA1$3.8 million0$0
Starks Associates, Inc.Buffalo, NY1$3.7 million0$0
University of California-BerkeleyBerkeley, CA6$3.6 million0$0
SUNY at Stony BrookStony Brook, NY8$3.5 million0$0
San Diego State University FoundationSan Diego, CA2$3.4 million0$0
Oklahoma State UniversityStillwater, OK2$3.4 million0$0
Akonni Biosystems, Inc.Frederick, MD2$3.3 million0$0
University of PennsylvaniaPhiladelphia, PA4$3.3 million0$0
Kaiser Foundation Research InstituteOakland, CA1$3.1 million0$0
Gryphon Scientific, LLCTakoma Park, MD1$3 million0$0
Triangle Biotechnology, Inc.Chapel Hill, NC1$3 million0$0
University of CincinnatiCincinnati, OH3$3 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025524$555,491,3640$0
2024545$560,034,7470$0
2023528$657,198,1400$0
2022531$774,034,4320$0
2021571$564,701,7050$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 7 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 3 awards here
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Not Allowed)PA-24-188NIHMay 7, 2027Not listedNotice number printed on 2 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185NIHMay 7, 2027Not listedNotice number printed on 1 award here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIHMay 7, 2027Not listedNotice number printed on 1 award here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)PA-24-184NIHMay 8, 2027Not listedNotice number printed on 1 award here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIHDecember 3, 2026Not listedNotice number printed on 1 award here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIHDecember 3, 2026Not listedNotice number printed on 1 award here
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)PA-25-304NIHJanuary 7, 2028Not listedNotice number printed on 1 award here
Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required)RFA-AI-27-002NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 875 awards here
Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)RFA-AI-27-005NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 875 awards here
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)PAR-25-370NIH93.855November 16, 2026$50,000Same assistance listing 93.855 as 875 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 875 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 875 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.855January 7, 2027Not listedSame assistance listing 93.855 as 875 awards here
HIV/AIDS Clinical Trials Network Leadership and Operations CentersRFA-AI-28-001NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 875 awards here
HIV/AIDS Clinical Trials Network Laboratory CentersRFA-AI-28-002NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 875 awards here
HIV/AIDS Clinical Trials Network Statistical and Data Management CentersRFA-AI-28-003NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 875 awards here
HIV/AIDS Clinical Trials Network Clinical Trials UnitsRFA-AI-28-004NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 875 awards here
Precision and Systems Biology to Uncover the Link Between Chronic and Infectious DiseasesRFA-AI-28-014NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 875 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.