Data / Research funding / Spinal Muscular Atrophy
Spinal Muscular Atrophy: 41 NIH awards ($50M) to 25 organizations
41 NIH awards ($50M) in the NIH spending category Spinal Muscular Atrophy, to 25 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.
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Awards
41 awards in the window.
| Award | Agency | Institute or division | Fiscal year | Amount in window | Start | End | Principal investigator | Source |
|---|---|---|---|---|---|---|---|---|
| Translating Pathomechanisms into Treatment for Spinal Muscular Atrophies | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $5,290,574 | May 5, 2021 | April 30, 2029 | SUMNER, CHARLOTTE JANE | reporter.nih.gov |
| Manipulating and Interrogating Spatial Transcriptomics | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $3,242,400 | September 1, 2023 | July 31, 2028 | QI, LEI STANLEY | reporter.nih.gov |
| Genetic Suppression of SMN Mutations in Spinal Muscular Atrophy | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,542,317 | July 1, 2021 | June 30, 2026 | BURGHES, ARTHUR H. M. | reporter.nih.gov |
| Mechanisms of Central Synaptic Dysfunction in SMA | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,443,464 | April 1, 2012 | April 30, 2028 | MENTIS, GEORGE Z | reporter.nih.gov |
| Biochemistry of Pre-mRNA Splicing | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $2,419,200 | July 1, 1989 | February 28, 2027 | KRAINER, ADRIAN R | reporter.nih.gov |
| Essential role of Stasimon in motor circuit development and disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,309,922 | December 1, 2019 | November 30, 2025 | PELLIZZONI, LIVIO | reporter.nih.gov |
| Mechanisms and SMN-Independent Therapies for Spinal Muscular Atrophy | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,966,695 | April 1, 2022 | March 31, 2027 | MONANI, UMRAO | reporter.nih.gov |
| Calcium Dysregulation and Cell Function in Spinal Muscular Atrophy | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $1,951,881 | January 20, 2021 | December 31, 2026 | FLAGG, THOMAS | reporter.nih.gov |
| Clinical Research Sites for the Network of Excellence in Neuroscience Clinical Trials (NeuroNEXT sites) (U24 Clinical Trial Not Allowed) | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $1,950,438 | July 15, 2018 | June 30, 2028 | MARDER, KAREN S | reporter.nih.gov |
| Mechanisms and Therapeutic Targeting of Motor Neuron Death in SMA | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $1,875,026 | February 1, 2020 | January 31, 2026 | PELLIZZONI, LIVIO | reporter.nih.gov |
| Oligodendrocyte-focused rAAV gene therapy strategies for Canavan disease and Leukodystrophies | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $1,838,158 | September 1, 2012 | January 31, 2030 | GAO, GUANGPING | reporter.nih.gov |
| DMA-Tudor interaction modules: a novel approach to Survival Motor Neuron protein (SMN) and Cajal body function | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,743,267 | July 15, 2022 | June 30, 2027 | NEUGEBAUER, KARLA M | reporter.nih.gov |
| RNA-Mediated Mechanisms of Motor System Dysfunction in Spinal Muscular Atrophy | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $1,643,716 | June 1, 2017 | February 28, 2029 | PELLIZZONI, LIVIO | reporter.nih.gov |
| Identifying the molecular mechanisms of GEMIN5 mutations in a novel cerebellar ataxia syndrome | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,603,046 | September 15, 2023 | June 30, 2028 | PANDEY, UDAI B | reporter.nih.gov |
| Novel SMARD1 Mouse Models: Characterization and Evaluation of Potential Therapeutic Targets | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $1,380,377 | February 1, 2020 | January 31, 2026 | LORSON, CHRISTIAN L. | reporter.nih.gov |
| Mechanisms of synaptic loss by the classical complement pathway in motor circuit development and disease | NIH | National Institute on Alcohol Abuse and Alcoholism | 2021 to 2022 | $1,340,135 | September 15, 2018 | June 30, 2024 | MENTIS, GEORGE Z | reporter.nih.gov |
| The functions of the zinc finger protein ZPR1 in R-loop metabolism and neurodegeneration. | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $1,203,169 | January 1, 2021 | January 2, 2023 | GANGWANI, LAXMAN DASS | reporter.nih.gov |
| Understanding the role of patient-derived Ighmbp2 mutations in neurodegeneration and pre-rRNA processing | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,181,939 | January 1, 2024 | December 31, 2028 | LORSON, CHRISTIAN L. | reporter.nih.gov |
| Cellular and Molecular Mechanisms of FUS-related ALS/FTD | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $1,161,739 | April 15, 2013 | January 31, 2025 | PANDEY, UDAI B | reporter.nih.gov |
| The COPA vesicle protein and pathogenesis of spinal muscular atrophy | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $1,151,742 | August 15, 2013 | April 30, 2025 | ANDROPHY, ELLIOT J. | reporter.nih.gov |
| Establishing Walking-related Digital Biomarkers in Rare Childhood Onset Progressive Neuromuscular Disorders | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2024 to 2025 | $1,068,101 | May 1, 2024 | March 31, 2028 | MONTES, JACQUELINE | reporter.nih.gov |
| Splicing Regulation of Spinal Muscular Atrophy Genes | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $1,004,064 | July 6, 2006 | March 31, 2025 | SINGH, RAVINDRA N | reporter.nih.gov |
| Dissecting RNA regulation in single cells and tissues | NIH | National Institute of General Medical Sciences | 2024 to 2025 | $828,132 | August 1, 2019 | May 31, 2029 | NORRIS, ADAM | reporter.nih.gov |
| The functions of the zinc finger protein ZPR1 in R-loop metabolism and neurodegeneration. | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $823,812 | January 1, 2021 | December 31, 2027 | GANGWANI, LAXMAN DASS | reporter.nih.gov |
| Spinal muscular atrophy: Mechanisms & treatment strategies. | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2022 | $793,297 | December 15, 2018 | November 30, 2024 | MONANI, UMRAO | reporter.nih.gov |
| Electrical impedance myography in an animal model | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2022 | $766,280 | August 1, 2007 | July 31, 2024 | RUTKOVE, SEWARD B. | reporter.nih.gov |
| Neuroinflammation and motor neuron loss in SMA | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $565,054 | September 1, 2023 | February 28, 2025 | EBERT, ALLISON D | reporter.nih.gov |
| Precision Base Editing for the Treatment of Motor Neuron Diseases | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2024 | $490,531 | August 1, 2021 | December 31, 2026 | ARBAB, MANDANA | reporter.nih.gov |
| Development of in Vivo Base Editing as a Genetic Treatment for Spinal Muscular Atrophy | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $488,483 | February 1, 2024 | August 31, 2025 | ALVES, CHRISTIANO | reporter.nih.gov |
| Biomarkers and additive therapies to enhance symptomatic treatment of Spinal Muscular Atrophy | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 | $461,828 | July 17, 2009 | April 30, 2023 | BURGHES, ARTHUR H. M. | reporter.nih.gov |
| Evaluating the feasibility of an innovative point-of-care screening tool for detection of infant motor delay within the newborn period | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 | $429,000 | August 22, 2023 | August 21, 2025 | ALFANO, LINDSAY N | reporter.nih.gov |
| The neuropathology of cerebellum in spinal muscular atrophy | NIH | National Institute of Neurological Disorders and Stroke | 2022 | $400,839 | March 1, 2022 | February 28, 2026 | SUN, JIANLI | reporter.nih.gov |
| IND Enabling Non-Clinical Development of E1v1.11, a Morpholino Anti-Sense Oligonucleotide for the treatment of Spinal Muscular Atrophy. | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $360,937 | April 1, 2023 | March 31, 2024 | OCONNOR, STEVE | reporter.nih.gov |
| Developmental mechanisms in the formation and function of sensory-motor circuits responsible for suckling and mastication. | NIH | National Institute of Dental & Craniofacial Research | 2024 to 2025 | $333,288 | September 1, 2024 | August 31, 2027 | FLOREZ PAZ, DANNY MAURICIO | reporter.nih.gov |
| Enhancing CRISPR-mediated homology-directed repair using anti-CRISPR proteins | NIH | National Institute of General Medical Sciences | 2022 | $256,580 | February 15, 2022 | November 14, 2022 | RABUKA, DAVID | reporter.nih.gov |
| Precision Base Editing for the Treatment of Motor Neuron Diseases | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2022 | $252,990 | August 1, 2021 | June 30, 2023 | ARBAB, MANDANA | reporter.nih.gov |
| Identifying Developmental and Degenerative Mechanisms of SMA Using Single Motor Neuron Nucleus RNA Sequencing | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $184,324 | August 9, 2024 | August 8, 2026 | MOLOTSKY, ELANA | reporter.nih.gov |
| Transcriptome-Wide Effect of Therapeutic Antisense Oligonucleotides for the Treatment of Spinal Muscular Atrophy | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $153,000 | May 1, 2024 | April 30, 2026 | SINGH, RAVINDRA N | reporter.nih.gov |
| Investigating the Role of the Helicase, IGHMBP2, and the RIG-I-Like Receptor Pathway in Spinal Muscular Atrophy with Respiratory Distress Type 1 and Neuromuscular Development (SMARD1) | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2023 | $62,446 | August 1, 2022 | July 31, 2024 | HOLBROOK, SARAH | reporter.nih.gov |
| The role of microglia in TRPV4 mediated neurodegeneration | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $49,538 | June 2, 2025 | December 1, 2026 | ALEVY, JONATHAN | reporter.nih.gov |
| Speech development in spinal muscular atrophy after disease-modifying therapies | NIH | National Institute on Deafness and Other Communication Disorders | 2025 | $37,973 | June 1, 2025 | May 31, 2027 | JENSEN, SYDNEY ANNMARIE | reporter.nih.gov |
Organizations
Funding by fiscal year
| Fiscal year | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|
| 2025 | 22 | $9,996,161 | 0 | $0 |
| 2024 | 22 | $10,693,312 | 0 | $0 |
| 2023 | 24 | $11,410,025 | 0 | $0 |
| 2022 | 21 | $9,330,425 | 0 | $0 |
| 2021 | 19 | $8,619,779 | 0 | $0 |
Open federal funding opportunities
From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.
Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.