Data / Research funding / Spina Bifida
Spina Bifida: 68 NIH awards ($67.8M) to 36 organizations
68 NIH awards ($67.8M) in the NIH spending category Spina Bifida, to 36 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.
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Awards
68 awards in the window.
| Award | Agency | Institute or division | Fiscal year | Amount in window | Start | End | Principal investigator | Source |
|---|---|---|---|---|---|---|---|---|
| Body Composition and Energy Expenditure in Youth with Spina Bifida | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2024 | $4,224,862 | July 1, 2019 | November 30, 2025 | POLFUSS, MICHELE | reporter.nih.gov |
| Human Umbilical Cord as a Regenerative Meningeal Patch to Prevent Tethering and Improve Neurological Function Following In-Utero Spina Bifida Repair | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $3,190,303 | April 1, 2021 | February 28, 2027 | PAPANNA, RAMESHA | reporter.nih.gov |
| Sleep-disordered breathing in infants with myelomeningocele | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,798,528 | January 15, 2020 | November 30, 2025 | BARKS, JOHN D | reporter.nih.gov |
| Intervention Strategies for Non-Folate Responsive Neural Tube Defects | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2024 | $2,575,383 | February 15, 2016 | July 31, 2025 | FINNELL, RICHARD H. | reporter.nih.gov |
| Autophagy and its Regulation in Diabetic Embryopathy | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2024 | $2,402,214 | May 7, 2014 | February 28, 2026 | YANG, PEIXIN | reporter.nih.gov |
| In vivo Evaluation of Safety and Pharmacology of the Sustained Release Formulation of Dolutegravir in Pre-Conception and Early Stages of Pregnancy in Animal Models | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2023 | $2,332,164 | September 13, 2019 | July 31, 2025 | KOVAROVA, MARTINA | reporter.nih.gov |
| Interdisciplinary approaches for understanding how arsenic and micronutrients affect the epigenome to influence spina bifida risk | NIH | National Institute of Environmental Health Sciences | 2023 to 2025 | $2,321,700 | January 20, 2023 | December 31, 2026 | MAZUMDAR, MAITREYI | reporter.nih.gov |
| Role of Slc25a32 and Its Interaction with Lrp6 in the Etiology of Neural Tube Defects | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2024 | $2,311,197 | March 10, 2020 | February 28, 2025 | LEI, YUNPING | reporter.nih.gov |
| Epitranscriptomic Alteration and Planar Cell Polarity Signaling In Diabetic Embroyopathy | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2024 | $2,294,873 | September 21, 2020 | July 31, 2025 | REECE, E. ALBERT | reporter.nih.gov |
| C. elegans Gastrulation: a Model for Understanding Apical Constriction Mechanisms | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,274,307 | January 1, 2020 | December 31, 2028 | GOLDSTEIN, ROBERT P | reporter.nih.gov |
| MicroRNA regulation of neural tube closure | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2024 | $2,271,604 | March 10, 2020 | February 28, 2025 | PARCHEM, RONALD J | reporter.nih.gov |
| Mechanisms of mechanotransduction during neural tube morphogenesis | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2025 | $2,145,119 | September 1, 2022 | June 30, 2027 | LU, XIAOWEI | reporter.nih.gov |
| Understanding Genetic Complexity in Spina Bifida | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $2,136,543 | September 12, 2023 | August 31, 2028 | ROSS, MARGARET ELIZABETH | reporter.nih.gov |
| Plausible Causative Mechanism for Dolutegravir Developmental Toxicity | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2023 | $2,023,722 | September 18, 2019 | July 31, 2025 | CABRERA, ROBERT M | reporter.nih.gov |
| Engineered Neuroprotective Stem-Cell Exosomes for In Utero Spina Bifida Therapy | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $1,972,069 | September 30, 2020 | August 31, 2025 | FARMER, DIANA LEE | reporter.nih.gov |
| Transposable Element Interaction and Its Impact on Human Development and Health | NIH | Office of the Director, National Institutes of Health | 2022 to 2025 | $1,909,873 | September 15, 2022 | August 31, 2027 | XIA, BO | reporter.nih.gov |
| Molecular drivers of tissue-specific morphogenetic programs | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2025 | $1,769,567 | June 22, 2022 | March 31, 2027 | WILLIAMS, MARGOT L.K. | reporter.nih.gov |
| Mechanisms of neural activity during neural tube formation | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $1,642,078 | January 15, 2020 | December 31, 2025 | BORODINSKY, LAURA NOEMI | reporter.nih.gov |
| Integrated Wnt Signaling and Maternal Intervention of Neural Tube Defects | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,495,378 | April 1, 2024 | March 31, 2029 | ZHOU, CHENGJI | reporter.nih.gov |
| Regulation of Cranial Mesenchyme Expansion Driving Neural Fold Elevation | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2024 | $1,487,808 | March 1, 2020 | February 28, 2026 | ZOHN, IRENE E | reporter.nih.gov |
| A Novel Smart Patch for the Fetoscopic Procedure to Repair Spina Bifida | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $1,341,740 | April 1, 2019 | March 31, 2025 | LIN, CHIA-YING JAMES | reporter.nih.gov |
| Dysregulated RNA metabolism in cell fate of maternal diabetes-induced neural tube defects | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2024 to 2025 | $1,336,422 | September 17, 2024 | June 30, 2029 | YANG, PEIXIN | reporter.nih.gov |
| Biomechanics of Neural Tube Development using Brillouin-OCT Multimodality | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2022 | $1,329,503 | September 1, 2018 | June 30, 2024 | LARIN, KIRILL V | reporter.nih.gov |
| Mechanisms of folate action during nervous system development | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $1,231,843 | May 15, 2019 | May 31, 2030 | BORODINSKY, LAURA NOEMI | reporter.nih.gov |
| Defining the impact of dolutegravir on the maternal metabolic environment and its implications on risk of congenital anomalies. | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2024 | $1,164,832 | September 20, 2020 | June 30, 2026 | SERGHIDES, LENA | reporter.nih.gov |
| Biomimetic intervention strategies for endogenous in utero repair of Spina Bifida | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2024 to 2025 | $1,145,380 | September 1, 2024 | May 31, 2029 | CORRADETTI, BRUNA | reporter.nih.gov |
| Epigenetic Mechanisms in Diabetic Embryopathy | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2022 | $1,089,190 | April 1, 2016 | March 31, 2025 | KAPPEN, CLAUDIA T | reporter.nih.gov |
| The Skeleton of Lateral Meningocele Syndrome | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2023 | $862,047 | July 18, 2018 | December 31, 2024 | CANALIS, ERNESTO | reporter.nih.gov |
| The Role of GPR161 in the Etiology of Neural Tube Defects | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2022 | $765,778 | September 1, 2018 | June 30, 2024 | FINNELL, RICHARD H. | reporter.nih.gov |
| Improving Kidney Health Assessment in Young Patients with Spina Bifida | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $760,320 | July 1, 2020 | September 30, 2025 | CHU, DAVID | reporter.nih.gov |
| Mechanisms of neural tube closure | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2022 | $741,562 | December 15, 2017 | November 30, 2023 | SOKOL, SERGEI | reporter.nih.gov |
| The role of extracellular matrix in Myelomeningocele | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2022 | $693,438 | September 1, 2018 | August 31, 2025 | KRYNSKA, BARBARA | reporter.nih.gov |
| Surface ectodermal mechanism and maternal intervention of neural tube defects | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2022 | $693,231 | April 1, 2018 | March 31, 2024 | ZHOU, CHENGJI | reporter.nih.gov |
| Cryopreserved Human Umbilical Cord as a Meningeal Patch in Fetoscopic Spina Bifida Repair (HUC-FICS): Single Arm Phase III Trial | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2025 | $620,820 | August 1, 2025 | July 31, 2030 | PAPANNA, RAMESHA | reporter.nih.gov |
| Engineering the fetal environment for in utero treatment of spina bifida bone defect | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $600,475 | March 24, 2025 | January 31, 2030 | HAO, DAKE | reporter.nih.gov |
| Molecular Basis for Individual Susceptibility to Neural Tube Defects | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 | $568,099 | April 1, 2016 | March 31, 2024 | KAPPEN, CLAUDIA T | reporter.nih.gov |
| The association between the urine microbiome, the host immune response and urinary symptoms in children with spina bifida | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2024 | $562,474 | April 1, 2022 | January 31, 2026 | FORSTER, CATHERINE S | reporter.nih.gov |
| Developing a reproductive health curriculum for adolescent girls with physical disabilities | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2024 | $508,680 | September 30, 2022 | August 31, 2025 | STREUR, COURTNEY S | reporter.nih.gov |
| A patient-centered approach to urinary incontinence and quality of life in childrenand adolescents with spina bifida | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $502,780 | June 1, 2019 | March 31, 2025 | SZYMANSKI, KONRAD | reporter.nih.gov |
| Evaluating Human Pluripotent Stem Cell-Derived Neural Rosette Arrays as a Neural Tube Defect Risk Screening Platform | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2022 | $427,438 | April 1, 2021 | September 30, 2023 | ASHTON, RANDOLPH S | reporter.nih.gov |
| Development of in vitro human spinal neural tube model to study genetic and environmental etiology of Spina Bifida. | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2024 to 2025 | $413,650 | August 5, 2024 | July 31, 2027 | KIM, SUNG EUN | reporter.nih.gov |
| The reverse hingepoint: a novel, essential feature of neurulation | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2022 | $413,519 | July 1, 2021 | June 30, 2024 | BREWSTER, RACHEL MELISSA | reporter.nih.gov |
| Healthy Adolescent and Young Adult Self-Management in Spina Bifida | NIH | National Institute of Nursing Research | 2021 to 2023 | $383,534 | February 26, 2021 | June 30, 2024 | RIDOSH, MONIQUE | reporter.nih.gov |
| Fetal Tissue Engineering to Treat Spina Bifida Before Birth | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $343,438 | August 1, 2017 | April 30, 2023 | WANG, AIJUN | reporter.nih.gov |
| Investigating Mechanisms of Force Transmission in Tissue Morphogenesis | NIH | National Institute of General Medical Sciences | 2021 | $330,549 | May 1, 2013 | December 31, 2022 | MARTIN, ADAM CHRISTOPHER | reporter.nih.gov |
| Stem cell-based biomaterials for spinal regeneration in neural tube defects | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 | $318,709 | September 1, 2017 | May 31, 2023 | KUNISAKI, SHAUN MICHAEL | reporter.nih.gov |
| Assessment of neural tube defects among newborns in Uganda: A study of prevalence, risk factors, and the role of gene-environmental interactions (NTDs in Uganda) | NIH | Fogarty International Center | 2022 to 2023 | $288,499 | September 21, 2022 | April 30, 2025 | HAGLUND, MICHAEL M. | reporter.nih.gov |
| Modeling genetic anencephaly with human brain organoids | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2023 | $247,714 | April 7, 2022 | March 31, 2024 | TIDBALL, ANDREW M | reporter.nih.gov |
| IMMUNE RESPONSES IN THE MOTHER-INFANT DYAD INDUCED BY FETAL SURGERY, AND ASSOCIATIONS WITH PREMATURITY | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $238,341 | February 24, 2020 | January 31, 2024 | ENNINGA, ELIZABETH ANN LIESER | reporter.nih.gov |
| A patient-centered approach to urinary incontinence in adults with spina bifida | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 | $237,750 | July 1, 2023 | June 30, 2025 | SZYMANSKI, KONRAD | reporter.nih.gov |
| Uncovering the cellular and molecular mechanisms of folic acid fortification in neural tube defects | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2024 | $221,230 | April 1, 2022 | March 31, 2025 | KAKEBEEN, ANNEKE D | reporter.nih.gov |
| Optically mapping tissue biomechanics during neural tube closure | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2023 | $219,604 | August 1, 2019 | July 31, 2024 | ZHANG, JITAO | reporter.nih.gov |
| Examining tissue-specific DNA methylation after prenatal exposure to arsenic among infants with spina bifida | NIH | National Institute of Environmental Health Sciences | 2021 | $216,875 | July 16, 2020 | June 30, 2023 | MAZUMDAR, MAITREYI | reporter.nih.gov |
| Evaluating teratogenic risk of anti-seizure medications in single-rosette brain organoids | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2022 | $214,500 | September 20, 2021 | August 31, 2023 | TIDBALL, ANDREW M | reporter.nih.gov |
| Beyond Folate - a Supplementation Strategy to Prevent Neural Tube Defects | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2025 | $187,500 | August 11, 2025 | July 31, 2027 | SALBAUM, JOHANNES MICHAEL | reporter.nih.gov |
| Functions of Lipid Homeostasis During Neural Tube Closure | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2025 | $140,400 | September 1, 2025 | August 31, 2027 | KAKEBEEN, ANNEKE D | reporter.nih.gov |
| Uterine Wall-Membrane Anchor Device for the Prevention of Preterm Premature Rupture of the Membranes Following Fetoscopic Surgery | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 | $139,727 | March 1, 2021 | July 31, 2023 | HEFFERNAN, MICHAEL JOHN | reporter.nih.gov |
| Archiving and Documenting Data from the NICHD MFMU Network and MOMS Studies | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2022 | $126,000 | March 11, 2021 | February 28, 2023 | MACPHERSON, CORA ANN BUCKLEY | reporter.nih.gov |
| Desirability Of Outcome Ranking (DOOR) Analyses for the NICHD MFMU and MOMS Studies | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2025 | $124,666 | June 1, 2025 | May 31, 2027 | SANDOVAL, GRECIO JAN | reporter.nih.gov |
| Optically mapping tissue biomechanics during neural tube closure | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 | $114,021 | August 1, 2019 | July 31, 2024 | ZHANG, JITAO | reporter.nih.gov |
| Mechanisms of Abnormal Cranial Mesenchyme Morphogenesis in the Hectd1 mutant | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2024 | $85,408 | March 15, 2023 | January 10, 2025 | MORAN, CLAIRE MARIE | reporter.nih.gov |
| Regulation of neuroectoderm morphogenesis by Nodal signaling programs | NIH | National Institute of General Medical Sciences | 2023 to 2024 | $81,069 | March 1, 2023 | July 15, 2024 | EMIG, ALYSSA NICOLE | reporter.nih.gov |
| MicroRNA-290 regulates maternal-fetal nutrient exchange during neural tube closure. | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2025 | $49,538 | August 14, 2025 | August 13, 2027 | HARRINGTON, MARGARET MARIA | reporter.nih.gov |
| Investigating the relationship between embryonic glucose homeostasis and neural tube closure | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2025 | $42,798 | April 1, 2025 | March 31, 2028 | FANDEL, JOSHUA YOSHIOKA | reporter.nih.gov |
| Experiences of Bowel Self-Management in Adults with Spina Bifida: A Qualitative Descriptive Study | NIH | National Institute of Nursing Research | 2023 | $41,336 | August 1, 2023 | July 31, 2024 | MRAVEC, MICHELLE LYNN | reporter.nih.gov |
| The 13th International Conference on Neural Tube Defects | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2024 | $21,388 | August 1, 2024 | July 31, 2025 | FINNELL, RICHARD H. | reporter.nih.gov |
| 12th International Conference on Neural Tube Defects | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 | $15,000 | May 1, 2022 | April 30, 2023 | FINNELL, RICHARD H. | reporter.nih.gov |
| Integrated Wnt signaling and maternal intervention of neural tube defects | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $1 | March 1, 2024 | March 31, 2024 | ZHOU, CHENGJI | reporter.nih.gov |
Organizations
Funding by fiscal year
| Fiscal year | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|
| 2025 | 19 | $8,780,334 | 0 | $0 |
| 2024 | 30 | $13,341,667 | 0 | $0 |
| 2023 | 35 | $13,971,894 | 0 | $0 |
| 2022 | 41 | $15,464,900 | 0 | $0 |
| 2021 | 38 | $16,223,313 | 0 | $0 |
Open federal funding opportunities
From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.
Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.