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Data / Research funding / Serious Mental Illness

Serious Mental Illness: 1,748 NIH awards ($2.3B) to 253 organizations

1,748 NIH awards ($2.3B) in the NIH spending category Serious Mental Illness, to 253 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Awards

The 500 largest of 1,748 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
ProNET: Psychosis-Risk Outcomes NetworkNIHNational Institute of Mental Health2021 to 2025$61,984,741September 8, 2020May 31, 2026WOODS, SCOTT Wreporter.nih.gov
ProCAN: Psychosis Risk Outcomes Compound Assessment NetworkNIHNational Institute of Mental Health2024 to 2025$31,583,752June 14, 2024May 31, 2029WOODS, SCOTT Wreporter.nih.gov
Trajectories and Predictors in the Clinical High Risk for Psychosis Population: Prediction Scientific Global Consortium (PRESCIENT)NIHNational Institute of Mental Health2021 to 2025$24,090,655September 8, 2020May 31, 2026NELSON, CHRISTOPHER BARNABYreporter.nih.gov
Psychosis Risk Evaluation, Data Integration and Computational Technologies (PREDICT): Data Processing, Analysis, and Coordination CenterNIHNational Institute of Mental Health2021 to 2024$23,322,808September 9, 2020May 31, 2026SHENTON, MARTHA E.reporter.nih.gov
Frontotemporal Dementia: Genes, Images, and EmotionsNIHNational Institute on Aging2021 to 2025$20,694,825September 1, 2002April 30, 2028GORNO TEMPINI, MARIA LUISAreporter.nih.gov
Analyses to Reveal Trajectories and Early Markers of Imminent Shifts in Suicidal StatesNIHNational Institute of Mental Health2025$19,515,757August 18, 2025August 17, 2029TURNER, JESSreporter.nih.gov
Dynamic Cognitive Phenotypes for Prediction of Mental Health Outcomes in Serious Mental IllnessNIHNational Institute of Mental Health2025$18,270,924September 10, 2025September 9, 2029GERMINE, LAURA THIreporter.nih.gov
Clinical Trial Data Processing, Analysis, and Coordination Center (CT-DPACC) for Accelerating Medicines Partnership Schizophrenia (AMP SCZ) ProjectNIHNational Institute of Mental Health2024 to 2025$12,671,179June 17, 2024May 31, 2029SHENTON, MARTHA E.reporter.nih.gov
1/4 Powering Genetic Discovery for Severe Mental Illness in Latin American and African AncestriesNIHNational Institute of Mental Health2021 to 2024$11,112,946September 14, 2020July 31, 2025NEALE, BENJAMIN MICHAELreporter.nih.gov
1/3 Genomics of Schizophrenia in the South African XhosaNIHNational Institute of Mental Health2021 to 2025$9,460,283January 1, 2021December 31, 2026KING, MARY-CLAIREreporter.nih.gov
HIV Center for Clinical and Behavioral StudiesNIHNational Institute of Mental Health2021 to 2025$9,131,244September 30, 1987April 30, 2028REMIEN, ROBERT Hreporter.nih.gov
Fragmented early-life experiences, aberrant circuit maturation, emotional vulnerabilitiesNIHNational Institute of Mental Health2021 to 2023$9,060,652June 17, 2013March 31, 2025BARAM, TALLIE Z.reporter.nih.gov
Identifying the genetic causes of depression in a deeply phenotyped population from South KoreaNIHNational Institute of Mental Health2021 to 2025$8,898,757August 17, 2021June 30, 2027FLINT, JONATHANreporter.nih.gov
A Latin American biobank for large-scale genetics research on severe mental illnessNIHNational Institute of Mental Health2021 to 2025$8,484,875May 1, 2020February 28, 2026FREIMER, NELSON B.reporter.nih.gov
Beyond GWAS: High Throughput Functional Genomics & Epigenome Editing to Elucidate the Effects of Genetic Associations for SchizophreniaNIHNational Institute of Mental Health2021 to 2025$8,050,699April 1, 2021January 31, 2027CRAWFORD, GREGORY Ereporter.nih.gov
Sex Differences in Major Depression: Impact of Prenatal Stress-Immune and Autonomic DysregulationNIHNational Institute of Mental Health2021 to 2024$7,968,668February 1, 2020April 24, 2025GOLDSTEIN, JILL Mreporter.nih.gov
1/4 Asian Bipolar Genetics Network (A-BIG-NET)NIHNational Institute of Mental Health2022 to 2025$7,964,900September 19, 2022July 31, 2027HUANG, HAILIANGreporter.nih.gov
Genetic Architecture of Early-Onset Psychosis in Mexicans (EPIMex)NIHNational Institute of Mental Health2023 to 2025$7,156,776July 14, 2023May 31, 2028GLAHN, DAVID Creporter.nih.gov
Neuroplasticity-Based Computerized Cognitive Remediation (nCCR) for Treatment Resistant Late-Life DepressionNIHNational Institute of Mental Health2021 to 2025$7,151,191April 15, 2021February 28, 2027MORIMOTO, SARAH SHIZUKOreporter.nih.gov
Understanding the molecular mechanisms that contribute to neuropsychiatric symptoms in Alzheimer DiseaseNIHNational Institute on Aging2021 to 2023$7,036,460September 15, 2019May 31, 2025ROUSSOS, PANAGIOTISreporter.nih.gov
2/2-Dopaminergic Dysfunction in Late-Life Depression (The D3 Study)NIHNational Institute of Mental Health2021 to 2024$6,409,923September 1, 2020June 30, 2026TAYLOR, WARREN Dreporter.nih.gov
Deep Brain Stimulation for Depression Using Directional Current Steering and Individualized Network TargetingNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$5,832,414September 15, 2017February 28, 2026SHETH, SAMEER ANILreporter.nih.gov
Early Psychosis Intervention Network (EPINET): Data Coordinating CenterNIHNational Institute of Mental Health2021 to 2023$5,780,626September 10, 2019June 30, 2025ROSENBLATT, ABRAMreporter.nih.gov
Multi-site, double-blind, randomized-controlled, efficacy trial of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction for depression symptoms in older adults with high suicide riskNIHNational Institute of Mental Health2024 to 2025$5,369,879September 1, 2024May 31, 2029SMAGULA, STEPHEN Freporter.nih.gov
Assay and Data Generation Center (ADGC) for the Model of iPSC-derived Neurons for NPD (MiNND)NIHNational Institute of Mental Health2023 to 2025$5,271,743May 17, 2023April 30, 2028PANG, ZHIPING P.reporter.nih.gov
Antecedents of Suicidal Behavior Related NeurobiologyNIHNational Institute of Mental Health2021 to 2022$5,218,211July 19, 2013June 30, 2024MANN, JOSEPH JOHNreporter.nih.gov
African Ancestry Genomic Psychiatry CohortNIHNational Institute of Mental Health2022 to 2024$5,119,918July 1, 2021June 30, 2026PATO, MICHELE Treporter.nih.gov
Developing Data-Driven Clinical Signatures for People Who Experience HallucinationsNIHNational Institute of Mental Health2024 to 2025$5,107,023April 1, 2024January 31, 2026BEN-ZEEV, DRORreporter.nih.gov
ICBT for Maternal Depression: Community Implementation in Head StartNIHNational Institute of Mental Health2021 to 2025$5,067,440April 1, 2021March 31, 2027FEIL, EDWARD GUSTAVreporter.nih.gov
Multiethnic genomic epigenomic and transcriptomic fine-mapping and functional validation analysis of schizophrenia and bipolar disorder risk lociNIHNational Institute of Mental Health2021 to 2025$4,996,628January 1, 2021October 31, 2026ROUSSOS, PANAGIOTISreporter.nih.gov
The ROSE Scale-Up Study: Informing a decision about ROSE as universal postpartum depression preventionNIHNational Institute of Mental Health2022 to 2025$4,984,007September 1, 2022June 30, 2027JOHNSON, JENNIFER Ereporter.nih.gov
Efficacy of biomarker-guided rTMS for treatment resistant depressionNIHNational Institute of Mental Health2022 to 2025$4,918,087April 5, 2019February 28, 2026LISTON, CONOR Mreporter.nih.gov
Characterizing Cognitive Decline in Late Life Depression: The ADNI-D ProjectNIHNational Institute of Mental Health2022 to 2025$4,842,533August 1, 2013May 31, 2027MACKIN, ROBERT SCOTTreporter.nih.gov
Electrophysiological Biomarkers to Optimize DBS for DepressionNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$4,795,842September 1, 2017December 31, 2023MAYBERG, HELEN Sreporter.nih.gov
California Collaborative Network to Promote Data Driven Care and Improve Outcomes in Early Psychosis (EPI-CAL)NIHNational Institute of Mental Health2021 to 2024$4,738,039September 10, 2019June 30, 2025NIENDAM, TARA ANNreporter.nih.gov
The BrainCellQTL consortium: QTL mapping in the human brain at the single cell levelNIHNational Institute on Aging2024 to 2025$4,701,117April 15, 2024March 31, 2029ROUSSOS, PANAGIOTISreporter.nih.gov
Aging of Emotion Circuitry and Risk for Alzheimer's disease: Impact of Sex, Immunity, and Fetal OriginsNIHNational Institute on Aging2021 to 2025$4,614,422June 15, 2018February 28, 2029GOLDSTEIN, JILL Mreporter.nih.gov
Early-phase Schizophrenia: Practice-based Research to Improve Treatment Outcomes (ESPRITO)NIHNational Institute of Mental Health2021 to 2023$4,449,258August 22, 2019May 31, 2025ROBINSON, DELBERT Greporter.nih.gov
Statistical methods to localize disease heritability and identify biological mechanismsNIHNational Institute of Mental Health2021 to 2025$4,419,743July 1, 2015May 31, 2028NEALE, BENJAMIN MICHAELreporter.nih.gov
Connecting FEP Research and Practice through a Learning Health SystemNIHNational Institute of Mental Health2021 to 2023$4,395,151September 7, 2020August 31, 2025BENNETT, MELANIE E.reporter.nih.gov
1/2 Neurodevelopmental and clinical trajectories of youth at risk for bipolar I disorderNIHNational Institute of Mental Health2021 to 2025$4,250,595August 1, 2021May 31, 2027STRAKOWSKI, STEPHEN Mreporter.nih.gov
Impact of Depression on Alzheimer's disease: Prenatal Immune Origins and Shared Impact of SexNIHNational Institute on Aging2021 to 2023$4,242,478September 15, 2019May 31, 2026GOLDSTEIN, JILL Mreporter.nih.gov
Latino Ancestry Genomic Psychiatry CohortNIHNational Institute of Mental Health2023 to 2025$4,213,714July 1, 2021June 30, 2026PATO, CARLOS Nreporter.nih.gov
Brain-based Mechanisms of Emotion Regulation in Aging and Mood DisordersNIHNational Institute of Mental Health2021 to 2025$4,145,728December 15, 2020October 31, 2025BURDICK, KATHERINE ELIZABETHreporter.nih.gov
Resolving complex alternative splicing of psychiatric disease genes using single-cell approachesNIHNational Institute of Mental Health2021 to 2025$4,123,629August 5, 2021May 31, 2026FANG, GANGreporter.nih.gov
2/3: Recurrence markers, cognitive burden and neurobiological homeostasis in late-life depression (REMBRANDT)NIHNational Institute of Mental Health2021 to 2024$4,088,394January 15, 2020November 30, 2025ANDREESCU, CARMENreporter.nih.gov
Neurobehavioral mechanisms of social isolation and loneliness in serious mental illnessNIHNational Institute of Mental Health2021 to 2025$4,041,167September 1, 2021June 30, 2026HOLT, DAPHNE Jreporter.nih.gov
Predictors and Moderators of Long-Term Outcome of Persons at Clinical High Risk for PsychosisNIHNational Institute of Mental Health2021 to 2024$4,025,952August 5, 2021May 31, 2026CADENHEAD, KRISTIN S.reporter.nih.gov
1/7 Clozapine for the Prevention of Violence in Schizophrenia: a Randomized Clinical TrialNIHNational Institute of Mental Health2021 to 2025$4,004,222July 1, 2021June 30, 2028GIRGIS, RAGY RAMSISreporter.nih.gov
Longitudinal neuroimaging and neurocognitive assessment of risk and protective factors across the schizophrenia spectrumNIHNational Institute of Mental Health2021 to 2024$4,002,004March 6, 2020December 31, 2025HAZLETT, ERIN A.reporter.nih.gov
Eating Disorders Genetics Initiative (EDGI)NIHNational Institute of Mental Health2021 to 2023$3,994,623September 11, 2019June 30, 2025BULIK, CYNTHIA Mreporter.nih.gov
Computational and electrochemical substrates of social decision-making in humansNIHNational Institute of Mental Health2021 to 2024$3,985,756August 1, 2020April 30, 2026MONTAGUE, P READreporter.nih.gov
Family-Focused Therapy for Individuals at High Clinical Risk for Psychosis: A Confirmatory Efficacy TrialNIHNational Institute of Mental Health2021 to 2023$3,965,959September 7, 2020July 31, 2025MIKLOWITZ, DAVID JAYreporter.nih.gov
Building Mood State Classifiers to Inform Deep Brain Stimulation (DBS) of Treatment-Resistant Bipolar DepressionNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$3,948,909September 1, 2024August 31, 2029GOODMAN, WAYNE Kreporter.nih.gov
Advancing the Early Psychosis Intervention Network in Texas (EPINET-TX)NIHNational Institute of Mental Health2021 to 2023$3,935,428September 11, 2020August 31, 2025LOPEZ, MOLLY A.reporter.nih.gov
Laminar dissection of cortical human brain gene expression in neuropsychiatric disordersNIHNational Institute of Mental Health2021 to 2025$3,916,231June 23, 2021September 30, 2026MARTINOWICH, KERIreporter.nih.gov
Imaging Hippocampal Function in PsychosisNIHNational Institute of Mental Health2021 to 2025$3,898,407February 7, 2005March 31, 2027HECKERS, STEPHANreporter.nih.gov
Invasive decoding and stimulation of altered reward computations in depressionNIHNational Institute of Mental Health2021 to 2025$3,889,326September 1, 2021June 30, 2027SAEZ, IGNACIOreporter.nih.gov
Depression treatment and Aβ dynamics: A study of Alzheimer’s disease riskNIHNational Institute on Aging2021 to 2025$3,865,122August 15, 2021July 31, 2027POMARA, NUNZIOreporter.nih.gov
1/3-Recurrence Markers, Cognitive Burden and Neurobiological Homeostasis in Late-life Depression (Rembrandt)NIHNational Institute of Mental Health2021 to 2024$3,857,339January 15, 2020November 30, 2025TAYLOR, WARREN Dreporter.nih.gov
Integrated Reward-Inflammation Model of First Onset of Major Depression in AdolescenceNIHNational Institute of Mental Health2021 to 2025$3,817,178April 1, 2021March 31, 2027ALLOY, LAUREN BERSHreporter.nih.gov
Integrated Reward-Circadian Rhythm Model of First Onset of Bipolar Spectrum Disorders in AdolescenceNIHNational Institute of Mental Health2021 to 2025$3,813,081September 1, 2021June 30, 2027ALLOY, LAUREN BERSHreporter.nih.gov
Predicting Recurrences in Bipolar Illness (Prompt-BD)NIHNational Institute of Mental Health2021 to 2025$3,784,986September 1, 2021December 31, 2026BIRMAHER, BORISreporter.nih.gov
Neural sensitivity to social evaluation and daily online and in-person social experience with peers: Predicting fluctuations in suicidality, self-harm, and depressive symptoms in adolescent girlsNIHNational Institute of Mental Health2021 to 2025$3,781,212August 1, 2021May 31, 2027SILK, JENNIFER Sreporter.nih.gov
Adaptive intervention to prevent adolescent suicidal behavior following psychiatric hospitalization: A Sequential Multiple Assignment Randomized TrialNIHNational Institute of Mental Health2021 to 2025$3,765,876September 7, 2021June 30, 2027CZYZ, EWA KARINAreporter.nih.gov
4/4 Powering Genetic Discovery for Severe Mental Illness in Latin American and African AncestriesNIHNational Institute of Mental Health2021 to 2024$3,744,312September 14, 2020July 31, 2025FREIMER, NELSON B.reporter.nih.gov
Personalized Integrated Chronotherapy for Perinatal DepressionNIHNational Institute of Mental Health2021 to 2023$3,730,568February 1, 2020June 30, 2025SHARKEY, KATHERINE Mreporter.nih.gov
Connectomic Deep Brain Stimulation for Obsessive Compulsive DisorderNIHNational Institute of Mental Health2021 to 2025$3,728,281May 1, 2021February 28, 2027CHOI, KI SUENGreporter.nih.gov
Targeting Cognition and Motivation in Coordinated Specialty Care for Early PsychosisNIHNational Institute of Mental Health2021 to 2024$3,709,389September 1, 2019July 31, 2025VINOGRADOV, SOPHIAreporter.nih.gov
Behavioral and Neural Heterogeneity in OCD and DepressionNIHNational Institute of Mental Health2021 to 2025$3,699,028August 5, 2021June 30, 2027STERN, EMILY Rreporter.nih.gov
Registration of spatial gene expression in key nodes of reward-related circuitry in the human brainNIHNational Institute on Drug Abuse2021 to 2025$3,694,469September 30, 2021April 30, 2027MARTINOWICH, KERIreporter.nih.gov
Cellular consequences and convergent biology of schizophrenia-associated rare variants in the diverse GPC cohortNIHNational Institute of Mental Health2022 to 2024$3,678,769August 1, 2022May 31, 2027MULLE, JENNIFER GLADYSreporter.nih.gov
Using human brain connectivity to identify the causal neuroanatomical substrate of depression symptomsNIHNational Institute of Mental Health2021 to 2025$3,675,908September 19, 2017June 30, 2027FOX, MICHAEL Dreporter.nih.gov
A Translational and Neurocomputational Evaluation of a D1R Partial Agonist for SchizophreniaNIHNational Institute of Mental Health2022$3,675,188September 23, 2019August 31, 2025KRYSTAL, JOHN H.reporter.nih.gov
Reducing disparities in cardiovascular health in community mental health settings: optimizing implementation strategiesNIHNational Heart, Lung, and Blood Institute2023 to 2025$3,663,171September 10, 2020August 31, 2027DAUMIT, GAIL L.reporter.nih.gov
Disrupted neural synchrony during naturalistic perception in schizophrenia: Toward a new biomarker of social dysfunctionNIHNational Institute of Mental Health2021 to 2025$3,630,321September 8, 2021August 31, 2026REAVIS, ERIC ANDREWreporter.nih.gov
Effort-Based Decision Making and Motivated Behavior in Everyday LifeNIHNational Institute of Mental Health2021 to 2025$3,601,764April 1, 2023January 31, 2028BARCH, DEANNAreporter.nih.gov
Improving Cognition Through Telehealth Aerobic Exercise and Cognitive Training After a First Schizophrenia EpisodeNIHNational Institute of Mental Health2023 to 2025$3,597,774May 1, 2023March 31, 2028NUECHTERLEIN, KEITH Hreporter.nih.gov
Risk and Resilience in Urban Black American Acute Trauma SurvivorsNIHNational Institute of Mental Health2021 to 2025$3,579,657September 16, 2021July 31, 2027LARSON, CHRISTINE Lreporter.nih.gov
Causal Role of Medial Prefrontal Neural Activity in Self-Agency in Schizophrenia (Admin Suppl)NIHNational Institute of Mental Health2021 to 2024$3,564,757May 1, 2020April 30, 2026SUBRAMANIAM, KARUNAreporter.nih.gov
Elucidating neural mechanisms of hypo/mania using theta burst stimulationNIHNational Institute of Mental Health2021 to 2025$3,562,499December 1, 2020October 31, 2025PHILLIPS, MARY LOUISEreporter.nih.gov
Reducing maternal prenatal depression to improve child cardiovascular healthNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,556,305January 15, 2021December 31, 2026DAVIS, ELYSIA POGGIreporter.nih.gov
3/3 Genomics of Schizophrenia in the South African XhosaNIHNational Institute of Mental Health2021 to 2025$3,535,299April 1, 2021December 31, 2025STEIN, DAN JOSEPHreporter.nih.gov
Phenotype Predictors of Cognitive Outcomes in Geriatric DepressionNIHNational Institute of Mental Health2021 to 2025$3,529,689September 13, 2016April 30, 2027STEFFENS, DAVID C.reporter.nih.gov
Longitudinal neuroprotectiveeffects of periconceptional folic acid supplements in help-seeking youth with psychiatric symptomsand healthy controlsNIHNational Institute of Mental Health2021 to 2024$3,513,898August 1, 2020May 31, 2026ROFFMAN, JOSHUA LAWRENCEreporter.nih.gov
Neural response to inflammatory challenge in major depressive disorderNIHNational Institute of Mental Health2021 to 2025$3,484,556May 14, 2021April 30, 2027SAVITZ, JONATHANreporter.nih.gov
Enhancing prefrontal oscillatory activity and working memory performance with noninvasive brain stimulation in early-course schizophreniaNIHNational Institute of Mental Health2021 to 2025$3,482,117September 7, 2021July 31, 2027FERRARELLI, FABIOreporter.nih.gov
Locomotor Activation and Mania Spectrum Risk: Circadian and Reward MechanismsNIHNational Institute of Mental Health2021 to 2025$3,477,441August 6, 2021February 28, 2027SOEHNER, ADRIANE M.reporter.nih.gov
Reward, impulsive sensation seeking and emotional dysregulation: neural mechanisms underlying risk for bipolar disorder in young adultsNIHNational Institute of Mental Health2021 to 2025$3,461,800January 1, 2024December 31, 2028PHILLIPS, MARY LOUISEreporter.nih.gov
Neuromodulatory control of prefrontal circuit function and reward-seekingNIHNational Institute of Mental Health2021 to 2025$3,445,646December 20, 2018October 31, 2028LISTON, CONOR Mreporter.nih.gov
OnTrackNY's LearningHealthcareSystemNIHNational Institute of Mental Health2021 to 2022$3,437,282August 15, 2019July 31, 2026DIXON, LISA B.reporter.nih.gov
2/2 Harnessing Hormonal Variation to Probe Neural Mechanisms and Optimize CBT Outcomes for OCDNIHNational Institute of Mental Health2021 to 2025$3,430,866September 1, 2021June 30, 2027BROWN, LILY Areporter.nih.gov
PATH-Pain: A Primary Care-Based Psychosocial Intervention To Improve Cognitive and Depression Outcomes in Older Adults with MCI and Early Stage ADNIHNational Institute on Aging2021 to 2025$3,411,409August 15, 2021July 31, 2027KIOSSES, DIMITRIS Nreporter.nih.gov
MicroRNA Correlates of Childhood Maltreatment and SuicidalityNIHNational Institute of Mental Health2021 to 2025$3,407,081April 16, 2021March 31, 2027DWIVEDI, YOGESHreporter.nih.gov
2/2-Neurodevelopmental and Clinical Trajectories of Youth at Risk for Bipolar DisorderNIHNational Institute of Mental Health2021 to 2025$3,382,572August 1, 2021May 31, 2027DELBELLO, MELISSA Preporter.nih.gov
Cerebellar Modulation of Cognition in PsychosisNIHNational Institute of Mental Health2021 to 2025$3,380,079January 7, 2019October 31, 2028BRADY, ROSCOE O.reporter.nih.gov
mHealth Mindfulness Intervention for Pregnant Black and Latina Women at Risk of Postpartum DepressionNIHNational Institute of Mental Health2021 to 2023$3,366,058July 1, 2021June 30, 2026KUBO, AIreporter.nih.gov
Multimodal Investigation of Excitatory/Inhibitory Imbalances and Network Dysfunction Related to Motor Control in OCD Youth: ¹H fMRS and fMRI ApplicationsNIHNational Institute of Mental Health2021 to 2025$3,361,339August 20, 1999October 30, 2026ROSENBERG, DAVID Rreporter.nih.gov
Therapeutic Efficacy of Ketamine Metabolites for Depression TreatmentNIHNational Institute of Mental Health2021 to 2025$3,353,675April 1, 2016January 31, 2027GOULD, TODD Dreporter.nih.gov
Negative Valence Systems in SchizophreniaNIHNational Institute of Mental Health2021 to 2025$3,348,565July 1, 2021May 31, 2027FEOLA, BRANDEEreporter.nih.gov
Clinical and Biomarker-Based Trajectories of Psychosis-Risk Populations in KenyaNIHNational Institute of Mental Health2021 to 2025$3,330,526August 18, 2021June 30, 2027MAMAH, DANIELreporter.nih.gov
Early Stage Identification and Engagement to Reduce the Duration of Untreated Psychosis: Evaluating the Impact of Screening and Systematic CommunicationNIHNational Institute of Mental Health2022 to 2025$3,324,711August 4, 2022June 30, 2027LANDA, YULIAreporter.nih.gov
Responsive Neurostimulation for Treatment Resistant DepressionNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$3,319,128June 15, 2023May 31, 2029KRYSTAL, ANDREW Dreporter.nih.gov
Depression and accelerated brain aging: A PET imaging studyNIHNational Institute of Mental Health2022 to 2024$3,319,066August 23, 2019May 31, 2026ESTERLIS, IRINAreporter.nih.gov
1/3 Eating Disorders Genetics Initiative 2 (EDGI2)NIHNational Institute of Mental Health2024 to 2025$3,305,679May 13, 2024February 28, 2029BULIK, CYNTHIA Mreporter.nih.gov
Probing the Functional and Behavioral Impact of Precision Circuit Modulation in Neuropsychiatric DisordersNIHNational Institute of Mental Health2022 to 2025$3,304,938September 7, 2022June 30, 2027ELDAIEF, MARK CHRISTIANreporter.nih.gov
Efficacy of digital cognitive behavior therapy for insomnia for the prevention of perinatal depressionNIHNational Institute of Mental Health2022 to 2025$3,292,920July 1, 2022April 30, 2027FELDER, JENNIFER NICOLEreporter.nih.gov
Aging and Disease Course: Contributions to Lifespan Neurobiology of SchizophreniaNIHNational Institute of Mental Health2021 to 2025$3,283,005July 1, 2021April 30, 2027IVLEVA, ELENA IVANOVNAreporter.nih.gov
Multi-center Randomized Controlled Trial of Refeeding an Anorexia NervosaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,275,089July 13, 2015March 31, 2027GARBER, ANDREA Kreporter.nih.gov
Development and clinical interpretation of machine learning emergency department suicide prediction algorithms using electronic health records and claimsNIHNational Institute of Mental Health2021 to 2024$3,265,508August 5, 2021May 31, 2026MARCUS, STEVEN Creporter.nih.gov
Implicit serial learningNIHNational Institute of Mental Health2021 to 2025$3,256,997July 5, 2018March 31, 2028FERRERA, VINCENT Preporter.nih.gov
1/2 Genetics at an extreme: an efficient genomic study of individuals with clinically severe major depression receiving ECTNIHNational Institute of Mental Health2021 to 2025$3,246,526September 23, 2019July 31, 2026ZANDI, PETER P.reporter.nih.gov
Anti-interneuron antibodies in rapid-onset pediatric OCD: clinical generalization and target identificationNIHNational Institute of Mental Health2022 to 2025$3,227,070September 1, 2022June 30, 2027PITTENGER, CHRISTOPHER JOHNreporter.nih.gov
A neurocomputational assay of gastrointestinal interoception in anorexia nervosaNIHNational Institute of Mental Health2021 to 2025$3,222,559September 1, 2021June 30, 2027KHALSA, SAHIB S.reporter.nih.gov
Loneliness in Aging with SchizophreniaNIHNational Institute of Mental Health2021 to 2024$3,222,032August 1, 2020June 30, 2026PALMER, BARTON W.reporter.nih.gov
Neurocognitive Abnormalities in Stimulant Abuse among High-Risk WomenNIHNational Institute on Drug Abuse2022 to 2025$3,207,045August 1, 2022May 31, 2027KIEHL, KENT Areporter.nih.gov
Early Intervention for Youth At-Risk for Bipolar DisorderNIHNational Institute of Mental Health2021 to 2025$3,205,610June 1, 2021May 31, 2027GOLDSTEIN, TINA Rreporter.nih.gov
Modeling and manipulating social percepts in individualsNIHNational Institute of Mental Health2022 to 2025$3,203,479May 17, 2022March 31, 2026FINN, EMILY SUZANNEreporter.nih.gov
Gene Dosage Imbalance in Neurodevelopmental DisordersNIHNational Institute of Mental Health2022 to 2025$3,189,018March 15, 2005December 31, 2026MARTIN, CHRISTA LESEreporter.nih.gov
A Trans-Nordic Study of Extreme Major DepressionNIHNational Institute of Mental Health2021 to 2024$3,180,792June 10, 2020March 31, 2026SULLIVAN, PATRICK Freporter.nih.gov
Glutamatergic adaptation to stress as a mechanism for anhedonia and treatment response with ketamineNIHNational Institute of Mental Health2022 to 2025$3,175,659March 1, 2022April 23, 2025TREADWAY, MICHAEL TILGHMANreporter.nih.gov
Multivariate methods for identifying multitask/multimodal brain imaging biomarkersNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2025$3,167,639April 1, 2007April 30, 2029CALHOUN, VINCE Dreporter.nih.gov
Data-driven subtyping in major depressive disorderNIHNational Institute of Mental Health2021 to 2024$3,146,195April 16, 2021February 28, 2026PERLIS, ROY H.reporter.nih.gov
Data-driven solutions for temporal, spatial, and spatiotemporal dynamic functional connectivityNIHNational Institute of Mental Health2021 to 2025$3,142,490March 19, 2021January 31, 2027CALHOUN, VINCE Dreporter.nih.gov
Remote computational phenotyping of behavioral and affective dynamics in major depressionNIHNational Institute of Mental Health2021 to 2024$3,137,387September 1, 2020June 30, 2026RUTLEDGE, ROBB BROOKSreporter.nih.gov
Toward Connectomic Deep Brain Stimulation in Obsessive Compulsive DisorderNIHNational Institute of Mental Health2022 to 2025$3,127,915August 1, 2022May 31, 2027FOX, MICHAEL Dreporter.nih.gov
Visual hallucinations and memory impairment in Parkinson's Disease: The role of hippocampal networksNIHNational Institute of Mental Health2021 to 2025$3,119,615September 1, 2021June 30, 2027BAKKER, ARNOLDreporter.nih.gov
Treatment Initiation for New Episodes of Depression in Pregnant WomenNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,116,370May 6, 2021March 31, 2027PALMSTEN, KRISTINreporter.nih.gov
Delineating the network effects of mental disorder-associated variants using convex optimization methodsNIHNational Institute of Mental Health2022 to 2025$3,110,527August 1, 2022May 31, 2027KNOWLES, DAVID ARTHURreporter.nih.gov
Integrative analysis of genetic variation and transcription factor networks to elucidate mechanisms of mental health disordersNIHNational Institute of Mental Health2021 to 2024$3,106,376April 1, 2015October 31, 2025BUSSEMAKER, HARMEN Jreporter.nih.gov
Early Life Stress and Depression: Molecular and Functional Imaging ApproachesNIHNational Institute of Mental Health2021 to 2024$3,104,069September 18, 2012April 30, 2026DU, FEIreporter.nih.gov
Gabapentin for Restoring GABA/glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders: A Randomized, Double-blind, Placebo-controlled, Parallel-group, Clinical MRI StudyNIHNational Institute on Drug Abuse2021 to 2025$3,103,371September 15, 2021June 30, 2026PRISCIANDARO, JAMES JOSEPHreporter.nih.gov
Dysregulation of Appetitive & Aversive Amygdala Circuits in Bipolar DisorderNIHNational Institute of Mental Health2021 to 2024$3,102,252May 20, 2020February 28, 2026BERRETTA, SABINAreporter.nih.gov
Group-based Prevention of Postpartum Depression: In-person vs. Virtual DeliveryNIHNational Institute of Mental Health2022 to 2025$3,089,717August 1, 2022June 30, 2027RHOADES, GALENAreporter.nih.gov
Neural, computational and behavioral characterization of dynamic social behavior in borderline and avoidant personality disorderNIHNational Institute of Mental Health2021 to 2025$3,089,337May 1, 2021February 28, 2026SCHILLER, DANIELAreporter.nih.gov
Neuroimaging Studies of Reward Processing in DepressionNIHNational Institute of Mental Health2022 to 2025$3,073,500March 1, 2022February 28, 2026PIZZAGALLI, DIEGO Areporter.nih.gov
The Impact of the COVID-19 Pandemic on Severe Mental IllnessNIHNational Institute of Mental Health2023$3,072,053April 15, 2023April 14, 2026FREIMER, NELSON B.reporter.nih.gov
Predicting psychosis risk in youth using a novel structural neuroimaging score that measures deviation from normative development. Can we bring it to communities using portable, low-field MRI?NIHNational Institute of Mental Health2022 to 2025$3,067,072May 1, 2022February 28, 2027JALBRZIKOWSKI, MARIAreporter.nih.gov
Adaptive DBS in Non-Motor Neuropsychiatric Disorders: Regulating Limbic Circuit ImbalanceNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$3,065,746September 30, 2016June 30, 2024GOODMAN, WAYNE Kreporter.nih.gov
Distinct Steroid Mechanisms in Menstrual Cycle Exacerbation of PsychopathologyNIHNational Institute of Mental Health2021 to 2025$3,060,986July 15, 2021May 31, 2027PETERS, JESSICA RACHAELreporter.nih.gov
A translational study of neuroinflammatory depression: Understanding mechanism and evaluation of a novel pharmacologic interventionNIHNational Institute of Mental Health2021 to 2024$3,060,008May 5, 2020February 28, 2026PARSEY, RAMIN V.reporter.nih.gov
Molecular Details of Psychoactive Drug ActionsNIHNational Institute of Mental Health2021 to 2025$3,047,615March 6, 2017November 30, 2026ROTH, BRYAN L.reporter.nih.gov
Fine-Mapping Genome-Wide Associated Loci using Multi-omics Data to Identify Mechanisms Affecting Serious Mental IllnessNIHNational Institute of Mental Health2021 to 2024$3,033,957January 1, 2021October 31, 2025MACDONALD, MATTHEW Lreporter.nih.gov
Decision Processes in Late-Life SuicideNIHNational Institute of Mental Health2021 to 2025$3,032,010September 15, 2010February 28, 2030GUJRAL, SWATHIreporter.nih.gov
1/2 Rare Genetic Variation and Risk for Obsessive Compulsive DisorderNIHNational Institute of Mental Health2021 to 2025$3,028,410December 15, 2020October 31, 2026GRICE, DOROTHY Ereporter.nih.gov
Phase III COBRE: Multimodal Imaging of Neuropsychiatric Disorders (MIND)NIHNational Institute of General Medical Sciences2021 to 2022$3,021,811May 18, 2018April 30, 2025MAYER, ANDREW ROBERTreporter.nih.gov
Relapse after Discontinuation of Antipsychotics during Pregnancy (R-DAP study)NIHNational Institute of Mental Health2021 to 2025$3,021,432March 2, 2020January 31, 2029BERGINK, VEERLEreporter.nih.gov
Dysregulation of dopamine receptors in the basal ganglia in OCD and tic disorders: Positron Emission Tomography with [11C]-PHNONIHNational Institute of Mental Health2022 to 2025$3,018,134August 1, 2022May 31, 2027PITTENGER, CHRISTOPHER JOHNreporter.nih.gov
Psychobiology of Suicidal Behavior in Borderline Personality DisorderNIHNational Institute of Mental Health2021 to 2025$3,010,846September 30, 1992January 31, 2028DOMBROVSKI, ALEXANDRE Y.reporter.nih.gov
Integrating case-control transcriptomic and genetic data in admixed individuals to identify disease genes for schizophrenia and bipolar disorderNIHNational Institute of Mental Health2021 to 2025$2,983,860April 6, 2018January 31, 2028OPHOFF, ROEL Areporter.nih.gov
Gene Expression Regulation in Brains of East Asian, African, and European Descent Explains Schizophrenia GWAS Across PopulationsNIHNational Institute of Mental Health2022 to 2025$2,975,872March 25, 2022January 31, 2027LIU, CHUNYUreporter.nih.gov
Ultra-high field GluCEST MRI and MRS in youth at risk for psychosisNIHNational Institute of Mental Health2021 to 2024$2,971,367May 10, 2020February 28, 2026ROALF, DAVID Rreporter.nih.gov
Interpersonal Stress, Social Media, and Risk for Adolescent Suicidal Thoughts and BehaviorsNIHNational Institute of Mental Health2025$2,968,897September 14, 2023July 31, 2028MELHEM, NADINE M.reporter.nih.gov
Using mHealth to improve adherence and reduce blood pressure in individuals with hypertension and bipolar disorderNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,965,831August 17, 2020April 30, 2026LEVIN, JENNIFER BETHreporter.nih.gov
Multi-level Mechanisms of Behavioral Activation Therapy for Adolescent DepressionNIHNational Institute of Mental Health2022 to 2025$2,950,939May 3, 2022February 28, 2027CRAIGHEAD, W. EDWARDreporter.nih.gov
Systems-Level Dysconnectivity in First Episode PsychosisNIHNational Institute of Mental Health2022 to 2025$2,948,956July 1, 2022April 30, 2027COFFMAN, BRIAN Areporter.nih.gov
Prenatal cannabis: A fetal neuroimaging study of neurodevelopmentNIHNational Institute on Drug Abuse2021 to 2025$2,937,376September 1, 2021June 30, 2027POSNER, JONATHAN Ereporter.nih.gov
The Impact of Depression and Preclinical Alzheimer Disease on Driving Among Older AdultsNIHNational Institute on Aging2021 to 2024$2,934,989June 15, 2020March 31, 2026BABULAL, GANESH Mreporter.nih.gov
Effectiveness of a multi-component mHealth intervention to improve post-hospital transitions of care for patients with SMINIHNational Institute of Mental Health2022 to 2025$2,933,730September 1, 2022July 31, 2027GAUDIANO, BRANDON Areporter.nih.gov
Social-Affective Vulnerability to Suicidality among LGBTQ Young Adults: Proximal and Distal FactorsNIHNational Institute of Mental Health2021 to 2024$2,924,151April 1, 2021March 20, 2025FORBES, ERIKA Ereporter.nih.gov
Incentive Processing and Learning in Anorexia Nervosa and Bulimia NervosaNIHNational Institute of Mental Health2022 to 2025$2,916,624February 15, 2022January 31, 2027WIERENGA, CHRISTINA Ereporter.nih.gov
Social Processing Deficits in Remitted Adolescent DepressionNIHNational Institute of Mental Health2021 to 2025$2,913,276December 1, 2019June 30, 2026AUERBACH, RANDY PATRICKreporter.nih.gov
Confirmatory Safety and Efficacy Trial of Magnetic Seizure Therapy for DepressionNIHNational Institute of Mental Health2021 to 2023$2,910,572August 1, 2017April 30, 2025BLUMBERGER, DANIEL M.reporter.nih.gov
Using Multimodal Neuroimaging and Real-World Experience Sampling to Understand Negative Affect and Paranoid Ideation in PsychosisNIHNational Institute of Mental Health2021 to 2024$2,903,780June 1, 2020April 30, 2026BLANCHARD, JACK J.reporter.nih.gov
Genetic Architecture of Early-Onset Psychosis in MexicansNIHNational Institute of Mental Health2021$2,899,776September 1, 2021August 31, 2023GLAHN, DAVID Creporter.nih.gov
Examining the Effects of Estradiol on Neural and Molecular Response to Rewards in Perimenopausal-Onset Anhedonia and PsychosisNIHNational Institute of Mental Health2022 to 2025$2,895,809January 1, 2022December 31, 2026DICHTER, GABRIEL Sreporter.nih.gov
An integrative computational interrogation of circuit dysfunction inschizophrenia via neural timescalesNIHNational Institute of Mental Health2022 to 2025$2,893,070September 15, 2022June 30, 2027HORGA, GUILLERMOreporter.nih.gov
Offline memory processing in schizophreniaNIHNational Institute of Mental Health2021 to 2025$2,888,672July 1, 2012December 31, 2027MANOACH, DARA Sreporter.nih.gov
Investigating Mechanisms of Intra- and Inter-individual Pain Variability in Patients with Comorbid Chronic Pain and DepressionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$2,884,008May 29, 2025April 30, 2028HERBERT, MATTHEW Sreporter.nih.gov
Cognitive Rehabilitation and Exposure Therapy for Geriatric HoardingNIHNational Institute of Mental Health2022 to 2025$2,879,948March 15, 2022December 31, 2026AYERS, CATHERINEreporter.nih.gov
Establishing Network Neuroscience Mechanisms of Efficiency of Evidence Accumulation in a Well-Characterized Sample with Bipolar Disorder: A Multi-Modal Clinical Imaging StudyNIHNational Institute of Mental Health2022 to 2025$2,877,100June 1, 2022March 31, 2027SRIPADA, CHANDRA SEKHARreporter.nih.gov
A translational approach for novel mechanisms of epigenetic regulation in treatment responses: toward a precision medicine modelNIHNational Institute of Mental Health2022 to 2025$2,876,042February 8, 2022December 31, 2026NASCA, CARLAreporter.nih.gov
Hormonal Mechanisms of Perimenopausal Risk for Psychosis in WomenNIHNational Institute of Mental Health2022 to 2025$2,866,305February 1, 2022January 31, 2027KLUMP, KELLY Lreporter.nih.gov
A data-driven reconceptualization of the RDoC construct of working memory: Neural correlates of underlying factors and implications for schizophreniaNIHNational Institute of Mental Health2021 to 2024$2,864,743March 17, 2020December 14, 2024VAN SNELLENBERG, JARED XAVIERreporter.nih.gov
Translational assessment of brain bioenergetic function in schizophreniaNIHNational Institute of Mental Health2021 to 2024$2,863,277December 1, 2019October 31, 2025MARANO, CHRISTOPHERreporter.nih.gov
From Manic Symptoms to Bipolar Disorder: Neural-behavioral Markers Using Two Analytic ModelsNIHNational Institute of Mental Health2021 to 2025$2,863,094March 1, 2020January 31, 2026DILER, RASIM SOMERreporter.nih.gov
Neural Mechanisms of Reading Dysfunction in SchizophreniaNIHNational Institute of Mental Health2021 to 2024$2,859,710July 1, 2020April 23, 2025JAVITT, DANIEL C.reporter.nih.gov
Fatigue, Anhedonia and Cardiac Prognostic Markers in Depressed Patients with Coronary Heart DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,842,930June 1, 2020May 31, 2025FREEDLAND, KENNETH Ereporter.nih.gov
Novel regulatory role of nuclear miRNAs in repatterning the transcriptional and post-transcriptional dynamics in MDD brainNIHNational Institute of Mental Health2022 to 2025$2,835,144July 15, 2022April 30, 2027DWIVEDI, YOGESHreporter.nih.gov
Comprehensive Human Expressed Sequences in Brain (CHESS-BRAIN) and their roles in neuropsychiatric illnessNIHNational Institute of Mental Health2021 to 2025$2,828,233March 2, 2021December 31, 2025SALZBERG, STEVEN L.reporter.nih.gov
Skills to Enhance Positivity (STEP) for Adolescents at Risk for SuicideNIHNational Institute of Mental Health2021 to 2025$2,817,698July 19, 2021June 30, 2026SPIRITO, ANTHONYreporter.nih.gov
iKinnect Mobile Technology to Reduce Teen Substance Misuse and Health DisparitiesNIHNational Institute on Drug Abuse2023 to 2025$2,814,384May 1, 2023April 30, 2027DIMEFF, LINDA Areporter.nih.gov
A prospective longitudinal study of transactional associations between social, neural, and hormonal changes and adolescent girls' mental health trajectoriesNIHNational Institute of Mental Health2022 to 2025$2,813,115May 12, 2022March 31, 2027PFEIFER, JENNIFER HOPEreporter.nih.gov
Development and testing of a digitally assisted risk reduction platform for youth at high risk for suicideNIHNational Institute of Mental Health2022 to 2025$2,810,090September 1, 2022December 31, 2026ALLEN, NICHOLAS Breporter.nih.gov
Attentional Biases for Affective Cues as a Mechanism of Risk in Children of Depressed MothersNIHNational Institute of Mental Health2022 to 2025$2,801,320July 1, 2022May 31, 2027GIBB, BRANDON Ereporter.nih.gov
Effectiveness RCT of Customized Adherence EnhancementNIHNational Institute of Mental Health2021 to 2024$2,799,926April 15, 2020March 31, 2026SAJATOVIC, MARTHA Xreporter.nih.gov
Using allopregnanolone to probe behavioral and neurobiological mechanisms that underlie depression in women across perimenopausal stageNIHNational Institute of Mental Health2022 to 2025$2,797,476February 1, 2022December 31, 2027JOFFE, HADINEreporter.nih.gov
Preventing postpartum depression among immigrant Latinas through a virtual group interventionNIHNational Institute on Minority Health and Health Disparities2022 to 2025$2,787,621September 18, 2022April 30, 2027TANDON, SHIV DARIUSreporter.nih.gov
Nicotinic Modulation of the Cognitive Control System in Late-Life DepressionNIHNational Institute of Mental Health2023 to 2025$2,784,647July 29, 2020November 30, 2026ANDREWS, PATRICIA SERRANOreporter.nih.gov
Cerebellar metabolism, neural circuits, and symptoms in bipolar disorderNIHNational Institute of Mental Health2021 to 2025$2,760,209September 20, 2017June 30, 2028MAGNOTTA, VINCENT Areporter.nih.gov
Cognitive Neuroscience of Attention and Working Memory in SchizophreniaNIHNational Institute of Mental Health2021 to 2025$2,759,904September 27, 2001June 30, 2029GOLD, JAMES M.reporter.nih.gov
Improving the Assessment of Pre-Teen Suicidal Thoughts and Behaviors in the Pediatric Emergency DepartmentNIHNational Institute of Mental Health2021 to 2023$2,751,642April 1, 2021January 31, 2027PAGLIACCIO, DAVIDreporter.nih.gov
Reward Learning in Late-Life Suicidal BehaviorNIHNational Institute of Mental Health2021 to 2024$2,745,458August 1, 2014February 28, 2026DOMBROVSKI, ALEXANDRE Y.reporter.nih.gov
Genetic Risk for Serious Mental Illness and DevelopmentNIHNational Institute of Mental Health2022 to 2025$2,714,386August 1, 2022May 31, 2027FORSYTH, JENNIFER KATHERINEreporter.nih.gov
Combining mHealth and nurse-delivered care to improve the outcomes of people with seriousmental illness in West AfricaNIHNational Institute of Mental Health2022 to 2025$2,710,919August 5, 2022May 31, 2027BEN-ZEEV, DRORreporter.nih.gov
The General Factor of Psychopathology in Psychosis and Severe Mental IllnessNIHNational Institute of Mental Health2021 to 2023$2,682,341August 1, 2019May 31, 2025HECKERS, STEPHANreporter.nih.gov
Empirical validation of a cerebellar-cortical hallucination circuitNIHNational Institute of Mental Health2022 to 2025$2,678,806January 1, 2022October 31, 2026HALKO, MARK Areporter.nih.gov
Active Surveillance of the Safety of Antipsychotic Medications in PregnancyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,677,870April 12, 2021March 31, 2027HUYBRECHTS, KRISTA Freporter.nih.gov
The impact of social isolation on aging health in schizophreniaNIHNational Institute of Mental Health2022 to 2025$2,674,394August 15, 2022May 31, 2027REICHENBERG, ABRAHAMreporter.nih.gov
Combining Voice and Genetic Information to Detect Heterogeneity in Major Depressive DisorderNIHNational Institute of Mental Health2021 to 2024$2,671,028August 14, 2020May 31, 2025FLINT, JONATHANreporter.nih.gov
Confirming the Efficacy/Mechanism of Family Therapy for Children with Low Weight Avoidant/Restrictive Food Intake Disorder (ARFID)NIHNational Institute of Mental Health2021 to 2024$2,666,817July 7, 2020June 30, 2026LOCK, JAMES Dreporter.nih.gov
Regulation of Gene Expression in the Human Habenula in Comorbid Opioid Addiction and DepressionNIHNational Institute on Drug Abuse2022 to 2025$2,665,324July 1, 2022April 30, 2027MAYNARD, KRISTEN ROSEreporter.nih.gov
Confirming the Effectiveness and Efficiency of Online Guided Self-Help Family-Based Treatment for Adolescent Anorexia NervosaNIHNational Institute of Mental Health2022 to 2025$2,642,941September 20, 2022July 31, 2027LOCK, JAMES Dreporter.nih.gov
Spatial Self Boundary, Interpersonal Distance and Social Impairments in SchizophreniaNIHNational Institute of Mental Health2022 to 2025$2,635,834August 1, 2022May 31, 2027PARK, SOHEEreporter.nih.gov
A feasibility trial of esketamine plus cognitive behavioral therapy for patients with major depressive disorder who are hospitalized for suicidal ideationNIHNational Institute of Mental Health2021 to 2023$2,634,706September 15, 2020August 31, 2025WILKINSON, SAMUELreporter.nih.gov
A Multidimensional Dissection of Antipsychotic Treatment Response in Early SchizophreniaNIHNational Institute of Mental Health2021 to 2025$2,629,702June 15, 2021April 30, 2027SARPAL, DEEPAK Kreporter.nih.gov
Identification of molecular rhythm changes in postmortem tissue from individuals with psychiatric illnessNIHNational Institute of Mental Health2021 to 2025$2,615,945July 10, 2018April 30, 2029MCCLUNG, COLLEEN Areporter.nih.gov
Unobtrusive Monitoring of Affective Symptoms and Cognition using Keyboard DynamicsNIHNational Institute of Mental Health2021 to 2024$2,613,912March 1, 2020December 31, 2025AJILORE, OLUSOLA A.reporter.nih.gov
Scalable Biomarkers and Generative Digital Twins for Personalized Neurostimulation in DepressionNIHNational Institute of Mental Health2022 to 2025$2,607,002September 15, 2022July 31, 2027GROSENICK, LOGANreporter.nih.gov
Improving Access and Treatment for Co-occurring Opioid Use Disorders and Mental IllnessNIHNational Institute of Mental Health2022 to 2024$2,601,753September 12, 2019February 28, 2026WATKINS, KATHERINE Ereporter.nih.gov
Inflammatory, mitochondrial and serotonergic interrelationships in the pathogenesis of major depressionNIHNational Institute of Mental Health2021 to 2024$2,601,711June 1, 2020February 28, 2026MANN, JOSEPH JOHNreporter.nih.gov
IPT for major depression following perinatal lossNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,601,028August 7, 2020July 31, 2026JOHNSON, JENNIFER Ereporter.nih.gov
Comparing the Effects of Prenatal Depression and its Treatment on Developmental Outcomes of the OffspringNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,597,768September 25, 2020August 31, 2026AVALOS, LYNDSAY AMMONreporter.nih.gov
Elucidating the Molecular Mechanisms of Neuropsychiatric Symptoms in Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2022$2,589,405September 30, 2018May 31, 2023KELLIS, MANOLISreporter.nih.gov
2/2 TRANS-ANCESTRY GENOMIC ANALYSIS OF OBSESSIVE COMPULSIVE DISORDERNIHNational Institute of Mental Health2021 to 2025$2,559,268August 17, 2021June 30, 2027STORCH, ERIC A.reporter.nih.gov
Next-generation, pathway-specific, polygenic risk scoresNIHNational Institute of Mental Health2021 to 2024$2,544,276April 1, 2020February 28, 2025O'REILLY, PAUL FRANCISreporter.nih.gov
Modeling Temporality with Natural Language Processing to Predict Readmission Risk of Patients with PsychosisNIHNational Institute of Mental Health2022 to 2025$2,541,970August 1, 2022May 31, 2027MILLER, TIMOTHY Areporter.nih.gov
Safety of Benzodiazepines and Non-Benzodiazepine Sedative Hypnotics in PregnancyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,533,175August 1, 2022April 30, 2027HUYBRECHTS, KRISTA Freporter.nih.gov
An Individualized, Multidimensional Dimensional Approach to PsychopathologyNIHNational Institute of Mental Health2021 to 2023$2,520,737August 1, 2019May 31, 2025CONSTABLE, R TODDreporter.nih.gov
Cross-Population Working Group on Genes and Environment in Major Depression (POP-GEM): Advancing the Understating of Etiology through DiversityNIHNational Institute of Mental Health2023 to 2025$2,514,140March 10, 2023October 31, 2026PETERSON, ROSEANN ELIZABETHreporter.nih.gov
5/5 CAPER: Computerized Assessment of Psychosis RiskNIHNational Institute of Mental Health2021 to 2024$2,513,960April 1, 2020February 28, 2026CORLETT, PHILIPreporter.nih.gov
Preventing Adult Mental Health Problems from Early Childhood in the Contexts of Genetic Susceptibility, Financial Strain, and Societal StressorsNIHNational Institute of Mental Health2023 to 2025$2,509,457January 1, 2023November 30, 2027WESTLING, ERIKAreporter.nih.gov
AMPA Receptor Components of the Antidepressant Response to Ketamine in HumansNIHNational Institute of Mental Health2023 to 2025$2,507,930July 3, 2023April 30, 2028DRIESEN, NAOMI Rreporter.nih.gov
Combination of Novel Therapies for CKD Comorbid Depression (CONCORD)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$2,506,802April 15, 2020September 1, 2023HEDAYATI, SUSANreporter.nih.gov
Elevating Voices, Addressing Depression, Toxic Stress and Equity in Group Prenatal Care (EleVATE GC)NIHNational Institute of Mental Health2021 to 2024$2,506,226September 21, 2020April 30, 2025LENZE, SHANNON NICOLEreporter.nih.gov
Leveraging Noninvasive Transcutaneous Vagus Nerve Stimulation and Smartphone Technology to Reduce Suicidal Behaviors and Suicide Among Highly Vulnerable AdolescentsNIHNational Institute of Mental Health2022 to 2024$2,500,913September 15, 2022July 31, 2027VALENTINO, KRISTINreporter.nih.gov
2/3 Sequencing and Trans-Diagnostic Phenotyping of Severe Mental Illness in Diverse PopulationsNIHNational Institute of Mental Health2022 to 2025$2,485,295September 1, 2022June 30, 2028CHARNEY, ALEXANDER Wreporter.nih.gov
2/3 Genomics of Schizophrenia in the South African XhosaNIHNational Institute of Mental Health2021 to 2025$2,483,989January 1, 2021December 31, 2026WALL, MELANIE Mreporter.nih.gov
Genome-Wide Association Analysis of Suicide DeathNIHNational Institute of Mental Health2021 to 2024$2,482,997August 17, 2020May 31, 2026DOCHERTY, ANNA R.reporter.nih.gov
mGluR5 hypoactivity is integral to glutamatergic dysregulation in schizophreniaNIHNational Institute of Mental Health2021 to 2024$2,475,825May 6, 2019November 30, 2025HAHN, CHANG-GYUreporter.nih.gov
Point-of-care prognostic modeling of PTSD risk after traumatic event exposure using digital biomarkers and clinical data from electronic health records in the emergency department setting (PREDICT)NIHNational Institute of Mental Health2023 to 2025$2,472,753July 10, 2023March 31, 2027SCHULTEBRAUCKS, KATHARINAreporter.nih.gov
The Proactive Screening and diagnosis of mild cognitive impairment and depression in patients aged 65 and over: An Implementation StudyNIHNational Institute on Aging2022 to 2023$2,472,345September 30, 2022August 31, 2025GLENN, SHENLYreporter.nih.gov
Achieving Cardiovascular Health Equity in Community Mental Health: Optimizing Implementation StrategiesNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,467,369September 10, 2020August 31, 2023DAUMIT, GAIL L.reporter.nih.gov
Neural Mechanisms of Voluntary Control Over HallucinationsNIHNational Institute of Mental Health2022 to 2024$2,459,914September 15, 2022July 31, 2027POWERS, ALBERT Rreporter.nih.gov
Collaborative Care Model for Perinatal Depression Support Services – Population-Level Upstream Systems Change (COMPASS-PLUS): A Hybrid Type 2 Cluster Randomized TrialNIHNational Institute of Nursing Research2023 to 2025$2,447,542September 19, 2023June 30, 2028MILLER, EMILY STINNETTreporter.nih.gov
Higher Order Chromatin and Genetic Risk for SchizophreniaNIHNational Institute of Mental Health2021 to 2023$2,446,779January 15, 2015July 31, 2025AKBARIAN, SCHAHRAMreporter.nih.gov
Genetic and Functional dissection of frontal thalamocortical circuitryNIHNational Institute of Mental Health2023 to 2025$2,446,235September 1, 2016March 31, 2028HALASSA, MICHAEL Mreporter.nih.gov
Using Ketamine to enhance memory reconsolidation and extinction of overgeneralized fear in individuals diagnosed with PTSDNIHNational Institute of Mental Health2023 to 2024$2,440,264May 15, 2023April 30, 2026HARPAZ-ROTEM, ILANreporter.nih.gov
The Role of Inflammation in CNS Mechanisms of Anhedonia and Psychomotor Slowing in Depressed PWH as Determined using a Next Generation TNF AntagonistNIHNational Institute of Mental Health2021 to 2025$2,439,698September 10, 2021August 31, 2027FELGER, JENNIFER Creporter.nih.gov
Drug interactions involving psychoactive drugsNIHNational Institute on Aging2021 to 2025$2,436,630February 1, 2019November 30, 2028LEONARD, CHARLES EDWARDreporter.nih.gov
Robust Learning Approaches for Assessing Effects and Effect Heterogeneity of Real World Antipsychotic Treatment Regimes in Elderly Persons with SchizophreniaNIHNational Institute of Mental Health2023 to 2025$2,435,333December 1, 2022October 31, 2027NORMAND, SHARON-LISE TERESAreporter.nih.gov
Real time neurofeedback, its neurotransmitter underpinnings, and therapeutic effects, in clinical high risk individualsNIHNational Institute of Mental Health2023 to 2024$2,431,728August 17, 2023July 31, 2026NIZNIKIEWICZ, MARGARET Areporter.nih.gov
Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression (TRIADE)NIHNational Institute of Mental Health2023 to 2025$2,426,941April 1, 2020January 31, 2027IOSIFESCU, DAN VLADreporter.nih.gov
Precision brain charts for imaging-genomics of schizophrenia and the psychosis spectrumNIHNational Institute of Mental Health2023 to 2025$2,414,787July 1, 2023March 31, 2028ALEXANDER-BLOCH, AARON FELIXreporter.nih.gov
Testing a Memory-Based Hypothesis for AnhedoniaNIHNational Institute of Mental Health2023 to 2025$2,413,789January 1, 2023October 31, 2027YASSA, MICHAEL Areporter.nih.gov
Reward Sensitivity as a Mechanism of Positive Affect Treatment for AnhedoniaNIHNational Institute of Mental Health2021 to 2023$2,411,248July 1, 2018May 31, 2025CRASKE, MICHELLE Greporter.nih.gov
Shifting Perspectives: Enhancing outcomes in adolescent anorexia nervosa with cognitive remediation therapyNIHNational Institute of Mental Health2021 to 2023$2,408,167May 1, 2019June 30, 2025TIMKO, C. ALIXreporter.nih.gov
Dynamic Neural Computations Underlying Cognitive Control in Bulimia NervosaNIHNational Institute of Mental Health2023 to 2025$2,406,304March 15, 2023December 31, 2027BERNER, LAURA A.reporter.nih.gov
Acute predictors of long-term post-trauma outcomes in youth victims of violenceNIHNational Institute of Mental Health2021 to 2024$2,395,782August 13, 2020June 30, 2026LARSON, CHRISTINE Lreporter.nih.gov
Biobehavioral perspectives on social connectedness and the “Mindful Moms” intervention for marginalized pregnant women with depressionNIHNational Institute of Nursing Research2021 to 2025$2,390,495May 6, 2021February 28, 2027KINSER, PATRICIA ANNEreporter.nih.gov
ENIGMA Bipolar Initiative: A Global Study of Imaging Genomics & Clinical OutcomesNIHNational Institute of Mental Health2022 to 2025$2,389,972April 1, 2022January 31, 2027THOMPSON, PAUL Mreporter.nih.gov
Reward processing in genetic frontotemporal dementia and mood disordersNIHNational Institute on Aging2021 to 2023$2,382,005March 1, 2019December 31, 2025PERRY, DAVID Creporter.nih.gov
Developing Neuronal KCNQ Channel Modulators for Mood DisordersNIHNational Institute of Mental Health2021 to 2023$2,380,565January 20, 2017February 28, 2025MURROUGH, JAMES WARRENreporter.nih.gov
Dopamine Availability and Developmental Pathways of Adolescent Depression and Anhedonia - Administrative SupplementNIHNational Institute of Mental Health2022 to 2024$2,379,519August 1, 2022March 21, 2025FORBES, ERIKA Ereporter.nih.gov
Computational Strategies to Tailor Existing Interventions for First Major Depressive Episodes to Inform and Test Personalized InterventionsNIHNational Institute of Mental Health2023 to 2025$2,378,286July 19, 2023May 31, 2028ERICKSON-RIDOUT, KATHRYN KELLYreporter.nih.gov
Ambulatory Monitoring of Threat Dysregulation in Adolescents at Risk for PsychosisNIHNational Institute of Mental Health2021 to 2024$2,374,005July 1, 2020April 30, 2026HORTON, LESLIE Ereporter.nih.gov
Inflammatory and Glutamatergic Mechanisms of Sustained Threat in Adolescents with Depression: Toward Predictors of Treatment Response and Clinical CourseNIHNational Institute of Mental Health2022 to 2025$2,371,670June 1, 2022April 30, 2028HO, TIFFANY CHEINGreporter.nih.gov
Low intensity focused ultrasound: a new paradigm for depression and anxietyNIHNational Institute of Mental Health2021 to 2024$2,364,204June 1, 2021March 31, 2026PHILIP, NOAH STEPHENreporter.nih.gov
Risk and resilience to late-life suicidal ideation and behavior after spousal bereavement: Targeting social connectedness to strengthen circadian rhythmicityNIHNational Institute of Mental Health2023 to 2025$2,361,884August 1, 2023May 31, 2028STAHL, SARAH Treporter.nih.gov
A Developmental Approach to Testing Suicidal Phenotypes in Early Childhood in Black YouthNIHNational Institute of Mental Health2023 to 2025$2,352,552August 22, 2023May 31, 2028STEPP, STEPHANIE Dreporter.nih.gov
1/5 CAPER: Computerized Assessment of ProdromE RiskNIHNational Institute of Mental Health2021 to 2024$2,347,166April 1, 2020February 28, 2026GOLD, JAMES M.reporter.nih.gov
In vivo imaging of a neural marker of suicidal behavior in Bipolar DisorderNIHNational Institute of Mental Health2021 to 2024$2,343,420December 1, 2018November 30, 2024ESTERLIS, IRINAreporter.nih.gov
Biobehavioral Predictors of Illness Progression in Adolescent DepressionNIHNational Institute of Mental Health2021 to 2023$2,338,927April 1, 2020October 6, 2023GABBAY, VILMAreporter.nih.gov
PREMAP - Predictors and Risk Evaluation for Menopause-Associated PsychosisNIHNational Institute of Mental Health2023 to 2025$2,337,777January 18, 2023October 31, 2027POWERS, ALBERT Rreporter.nih.gov
The 3D genome in transcriptional regulation across the postnatal life span, with implications for schizophrenia and bipolar disorderNIHNational Institute of Mental Health2021 to 2022$2,335,974September 1, 2018May 31, 2024ROUSSOS, PANAGIOTISreporter.nih.gov
Identification of Epigenetics Correlates between Brain and Peripheral TissuesNIHNational Institute of Mental Health2021 to 2024$2,327,859June 11, 2021November 30, 2025SHINOZAKI, GENreporter.nih.gov
3/3-Recurrence markers, cognitive burden and neurobiological homeostasis in late-life depressionNIHNational Institute of Mental Health2021 to 2024$2,327,640January 1, 2020November 30, 2024AJILORE, OLUSOLA A.reporter.nih.gov
Integrating a Stepped Care Model of Screening and Treatment for Depression into Malawi's National HIV Care Delivery PlatformNIHNational Institute of Mental Health2021 to 2024$2,324,116July 1, 2020June 30, 2025MCBAIN, RYAN Kreporter.nih.gov
Implementing and Sustaining a Transdiagnostic Sleep and Circadian Treatment to Improve Severe Mental Illness Outcomes in Community Mental Health.NIHNational Institute of Mental Health2021 to 2023$2,323,419September 5, 2019February 28, 2025HARVEY, ALLISON Greporter.nih.gov
Establishing that sleep spindle and slow wave deficits are present, are associated with cognitive dysfunction, and can be acutely manipulated in early course schizophreniaNIHNational Institute of Mental Health2023 to 2025$2,321,854June 1, 2023March 31, 2028FERRARELLI, FABIOreporter.nih.gov
Deep Brain Stimulation for Chronic Auditory Hallucinations in Treatment-Resistant Schizophrenia: an early-stage clinical trialNIHNational Institute of Mental Health2023 to 2025$2,302,854May 1, 2023February 28, 2027CASCELLA, NICOLA Greporter.nih.gov
1/4-Deciphering Mechanisms of ECT Outcomes and Adverse Effects (DECODE)NIHNational Institute of Mental Health2022 to 2025$2,301,244August 1, 2022May 31, 2027NARR, KATHERINE Lreporter.nih.gov
2/3 Understanding PTSD through Postmortem Targeted Brain Multi-omicsNIHNational Institute of Mental Health2021 to 2025$2,300,674July 25, 2018February 28, 2030KLEINMAN, JOEL EDWARDreporter.nih.gov
Neural Circuit-Specific Mechanisms of Ketamine's Effect on Anhedonia and Anxiety in Depression Using Ultra-High Field 7-Tesla MRINIHNational Institute of Mental Health2023 to 2025$2,300,316July 21, 2023April 30, 2028MURROUGH, JAMES WARRENreporter.nih.gov
Early life adversities and the emergence of risk and resilience: a longitudinal study of child developmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,298,860May 1, 2014April 30, 2026MASELKO, JOANNAreporter.nih.gov
Human brain multi-omics to decipher major depression pathophysiologyNIHNational Institute of Mental Health2025$2,298,210September 1, 2023June 30, 2028DUPONT, MAURA BOLDRINIreporter.nih.gov
A Wearable Morning Light Treatment for Postpartum Depression: Confirming Efficacy and MechanismsNIHNational Institute of Mental Health2021 to 2024$2,298,045February 1, 2021January 31, 2026SWANSON, LESLIE Mreporter.nih.gov
in vivo investigation of KOR as a marker of BPD and suicide related endophenotypesNIHNational Institute of Mental Health2023 to 2025$2,292,119June 20, 2023April 30, 2026DAVIS, MARGARET TAYLORreporter.nih.gov
2/4 Powering Genetic Discovery for Severe Mental Illness in Latin American and African AncestriesNIHNational Institute of Mental Health2021 to 2024$2,287,666September 18, 2020July 31, 2025KOENEN, KARESTAN Creporter.nih.gov
A translational approach for identifying factors and mechanisms underlying pathological anxiety in preadolescent girlsNIHNational Institute of Mental Health2023 to 2025$2,284,661June 21, 2023April 30, 2026KALIN, NED Hreporter.nih.gov
Developmental Pathways to Borderline Personality Disorder: Longitudinal Observational, Clinical, and Neural Predictors From Early Childhood to Young AdulthoodNIHNational Institute of Mental Health2023 to 2025$2,281,837May 1, 2010April 30, 2026WHALEN, DIANA Jreporter.nih.gov
Mindfulness-based Neurofeedback to augment DBT psychotherapy for adults with Borderline Personality Disorder (MIND-BPD)NIHNational Institute of Mental Health2024 to 2025$2,275,682September 1, 2024May 31, 2027FINEBERG, SARAH Kreporter.nih.gov
Cognitive Genomics as a Window on Neurodevelopment and PsychopathologyNIHNational Institute of Mental Health2021 to 2025$2,275,324June 8, 2018November 30, 2028LENCZ, TODDreporter.nih.gov
Neurobiologically-Based Subtyping of Multi-Cohort Samples with MDD and PTSD SymptomsNIHNational Institute of Mental Health2022 to 2025$2,273,831April 15, 2022January 31, 2026MOREY, RAJENDRA Areporter.nih.gov
Longitudinal Personalized Dynamics Among Anorexia Nervosa Symptoms, Core Dimensions, and Physiology Predicting Suicide RiskNIHNational Institute of Mental Health2023 to 2025$2,270,862September 1, 2023June 30, 2028LEVINSON, CHERI ALICIAreporter.nih.gov
Visual perception as a window onto prediction anomalies in schizophreniaNIHNational Institute of Mental Health2021 to 2025$2,266,778April 1, 2021January 31, 2027THAKKAR, KATHARINE NATASHAreporter.nih.gov
Improving the interpretability of genetic studies of major depressive disorder to identify risk genesNIHNational Institute of Mental Health2022 to 2025$2,264,530June 16, 2022April 30, 2027FLINT, JONATHANreporter.nih.gov
Randomized Controlled Trial of a Novel Smoking Cessation Application Tailored to Individuals with Serious Mental IllnessNIHNational Institute on Drug Abuse2021 to 2024$2,258,650March 15, 2020March 31, 2024VILARDAGA, ROGERreporter.nih.gov
Rule-Based Decision-Making: A Novel Neuroeconomic Mechanism of Anorexia NervosaNIHNational Institute of Mental Health2022 to 2025$2,258,099September 15, 2022May 31, 2027HAYNOS, ANN FRANCESreporter.nih.gov
Suicidality in Bipolar and Major Depression DisordersNIHNational Institute of Mental Health2022 to 2024$2,256,258September 1, 2022June 30, 2027MAGNOTTA, VINCENT Areporter.nih.gov
Neurostimulation Enhanced Cognitive Restructuring for Transdiagnostic Emotional Dysregulation: A Component AnalysisNIHNational Institute of Mental Health2023 to 2025$2,256,194January 1, 2023October 31, 2027NEACSIU, ANDRADA DELIAreporter.nih.gov
Leveraging EHR data to evaluate key treatment decisions to prevent suicide-related behaviorsNIHNational Institute of Mental Health2021 to 2023$2,252,602January 1, 2020October 31, 2025KESSLER, RONALD Creporter.nih.gov
Dynamic Impacts of Sleep Disruption on Ecologically Assessed Affective, Behavioral, and Cognitive Risk Factors for SuicideNIHNational Institute of Mental Health2021 to 2024$2,247,422December 1, 2020October 31, 2025ARMEY, MICHAEL Freporter.nih.gov
An Integrative Approach to the Etiology of Internalizing Disorders in the Lifelines CohortNIHNational Institute of Mental Health2022 to 2025$2,246,333December 10, 2021October 31, 2026KENDLER, KENNETH SEEDMANreporter.nih.gov
Mechanisms of Depression and Anhedonia in Adolescents: Linking Sleep Duration and Timing to Reward- and Stress-Related Brain FunctionNIHNational Institute of Mental Health2022 to 2024$2,246,194February 10, 2022December 31, 2027CASEMENT, MELYNDA Dreporter.nih.gov
Memantine augmentation of cognitive training in schizophreniaNIHNational Institute of Mental Health2021 to 2023$2,246,161February 16, 2021December 31, 2024LIGHT, GREGORY Areporter.nih.gov
Temperamental emotionality in preschoolers and depression riskNIHNational Institute of Mental Health2021 to 2023$2,245,293July 1, 2004June 30, 2026KLEIN, DANIEL Nreporter.nih.gov
1/3 Sequencing and Trans-Diagnostic Phenotyping of Severe Mental Illness in Diverse PopulationsNIHNational Institute of Mental Health2022 to 2025$2,242,089September 1, 2022June 30, 2028SULLIVAN, PATRICK Freporter.nih.gov
Confirmatory Efficacy Clinical Trial of Amygdala Neurofeedback for DepressionNIHNational Institute of Mental Health2023 to 2025$2,234,937February 18, 2025May 31, 2025YOUNG, KYMreporter.nih.gov
Treating Drivers of Suicide in Primary Care using Jaspr Health TABA SupplementNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2023$2,232,676May 3, 2023August 31, 2023DIMEFF, LINDA Areporter.nih.gov
Measurement and manipulation of oscillatory biomarker of working memory in psychosisNIHNational Institute of Mental Health2021 to 2024$2,220,095March 5, 2020January 31, 2026ERICKSON, MOLLYreporter.nih.gov
Site 3/3, Understanding PTSD through Postmortem Targeted Brain MultiomicsNIHNational Institute of Mental Health2021 to 2025$2,218,601July 25, 2018February 28, 2030RESSLER, KERRY J.reporter.nih.gov
Individualized brain biomarkers of late life depression: contributions to heterogeneity and resilienceNIHNational Institute of Mental Health2022 to 2025$2,218,176August 5, 2022May 31, 2027BIJSTERBOSCH, JANINE DIANEreporter.nih.gov
Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in AdolescentsNIHNational Institute of Mental Health2022 to 2024$2,213,790August 16, 2022June 30, 2027DWIVEDI, YOGESHreporter.nih.gov
Cellular consequences and convergent biology of schizophrenia-associated rare variants in the GPC cohortNIHNational Institute of Mental Health2025$2,209,242August 1, 2022May 31, 2027MULLE, JENNIFER GLADYSreporter.nih.gov
The schizophrenia-associated 3q29 deletion: genetic architecture of behavioral phenotypesNIHNational Institute of Mental Health2023 to 2025$2,208,465March 24, 2023December 31, 2026MULLE, JENNIFER GLADYSreporter.nih.gov
Validating of Machine Learning-Based EEG Treatment Biomarkers in DepressionNIHNational Institute of Mental Health2021 to 2022$2,200,606March 1, 2020February 29, 2024ETKIN, AMITreporter.nih.gov
Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCDNIHNational Institute of Mental Health2021 to 2023$2,191,470December 1, 2018May 31, 2024PITTENGER, CHRISTOPHER JOHNreporter.nih.gov
Neuroimaging Dimensions at the Extremes of the Schizophrenia SpectrumNIHNational Institute of Mental Health2023 to 2025$2,186,001September 15, 2023June 30, 2028VAN ERP, THEODORUS G.M.reporter.nih.gov
Prenatal Environmental Mixtures, Cognitive Control and Reward Processes, And Risk for Psychiatric Problems in Adolescence.NIHNational Institute of Environmental Health Sciences2021 to 2024$2,184,629September 1, 2021May 31, 2025MARGOLIS, AMYreporter.nih.gov
Transdiagnostic Reward System Dynamics and Social Disconnection in SuicideNIHNational Institute of Mental Health2023 to 2025$2,183,248May 18, 2023February 29, 2028DEPP, COLIN A.reporter.nih.gov
Drug Interactions Involving Second-generation Antipsychotic Agents Leading to Sudden Cardiac ArrestNIHNational Institute of Mental Health2022 to 2024$2,181,418July 6, 2022May 31, 2026HENNESSY, SEANreporter.nih.gov
Inflammatory factors and kynurenine metabolites tracking suicidal behaviorNIHNational Institute of Mental Health2021 to 2023$2,179,414July 1, 2019April 30, 2025BRUNDIN, LENA CECILIAreporter.nih.gov
Mother-Infant Biobehavioral Synchrony and Postpartum DepressionNIHNational Institute of Mental Health2023 to 2025$2,177,031February 1, 2023October 31, 2027MORGAN, JUDITH K.reporter.nih.gov
Distinguishing Clinical and Genetic Risk of Suicidal Ideation from Attempts to Inform PreventionNIHNational Institute of Mental Health2021 to 2024$2,174,944December 1, 2019October 31, 2024WALSH, COLIN GEORGEreporter.nih.gov
Evolution of Psychosis in Youth: Multimodal Risk and Resilience MarkersNIHNational Institute of Mental Health2021 to 2023$2,174,697July 15, 2019April 30, 2025GUR, RAQUEL Ereporter.nih.gov
Optimizing Mindfulness and Acceptance-Based Treatments for Bulimia Nervosa and Binge Eating Disorder using a Factorial DesignNIHNational Institute of Mental Health2021 to 2023$2,172,458April 1, 2020March 31, 2025JUARASCIO, ADRIENNE SARAHreporter.nih.gov
Utilizing changes in human brain connectivity to establish a dose-response relationship involved in the therapeutic actions of prefrontal brain stimulation on depression symptomsNIHNational Institute of Mental Health2021 to 2024$2,171,935April 1, 2020February 28, 2026WILLIAMS, NOLAN R.reporter.nih.gov
Limbix Spark: a CBT-based mobile intervention for adolescent depressionNIHNational Institute of Mental Health2021 to 2022$2,170,897February 1, 2021October 31, 2023LAKE, JESSICAreporter.nih.gov
Examining Intensive Outpatient Programs as a Potential Mechanism to Reduce Suicide Risk During the Post-Hospitalization Period Among Medicaid RecipientsNIHNational Institute of Mental Health2023 to 2025$2,170,611September 11, 2023July 31, 2028WILKINSON, SAMUELreporter.nih.gov
2/2 Genetics at an extreme: an efficient genomic study of individuals with clinically severe major depression receiving ECTNIHNational Institute of Mental Health2021 to 2023$2,169,657September 23, 2019July 31, 2025SULLIVAN, PATRICK Freporter.nih.gov
Testing a Dyadic Model of Proximal Suicide Risk in Young Adult Romantic CouplesNIHNational Institute of Mental Health2023 to 2025$2,168,826February 15, 2023December 31, 2027STEPP, STEPHANIE Dreporter.nih.gov
Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCDNIHNational Institute of Mental Health2023 to 2025$2,164,606August 23, 2023July 31, 2028RODRIGUEZ, CAROLYN Ireporter.nih.gov
Neurodevelopment and Psychosis in the 22q11.2 Copy Number VariantsNIHNational Institute of Mental Health2023 to 2025$2,163,535December 14, 2009April 30, 2028BEARDEN, CARRIE Ereporter.nih.gov
The Dopamine Synapse and Associative LearningNIHNational Institute on Drug Abuse2021 to 2025$2,161,538July 1, 1991December 31, 2028SULZER, DAVIDreporter.nih.gov
Cognitive Reappraisal Training Targeting Emotion Circuits As a Therapeutic Intervention in Borderline PatientsNIHNational Institute of Mental Health2024 to 2025$2,154,493December 1, 2020July 31, 2027KOENIGSBERG, HAROLD Wreporter.nih.gov
Relationships between Neuroactive Steroids, GABA and Glutamate MRS and Connectivity of the Default Mode Network in Postpartum DepressionNIHNational Institute of Mental Health2021 to 2024$2,150,253May 4, 2020February 28, 2026DELIGIANNIDIS, KRISTINA MARIEreporter.nih.gov
A Confirmatory Efficacy Trial of Engaging a Novel Sleep/Circadian Rhythm Target as Treatment for Depression in AdolescentsNIHNational Institute of Mental Health2023 to 2025$2,148,946March 1, 2023May 31, 2025ASARNOW, LAURENreporter.nih.gov
Harnessing advances in the genetics of suicidality to identify and dissect psychosocial pathways to riskNIHNational Institute of Mental Health2022 to 2025$2,144,932March 1, 2022December 31, 2026EDWARDS, ALEXIS Creporter.nih.gov
Eating Disorders Across Genders, Generations, and Adult Developmental StagesNIHNational Institute of Mental Health2021 to 2025$2,141,933July 1, 2021April 30, 2027KEEL, PAMELA K.reporter.nih.gov
Visual Remediation in SchizophreniaNIHNational Institute of Mental Health2021 to 2023$2,138,056February 8, 2018July 31, 2025SILVERSTEIN, STEVEN Mreporter.nih.gov
Potentiate Cav3.3 To Treat Cognitive Deficits Associated with Impaired Sleep SpindleNIHNational Institute of Mental Health2025$2,128,784September 1, 2022June 30, 2028PAN, JEN QIANreporter.nih.gov
Determining the role of social reward learning in social anhedonia in first-episode psychosis using motivational interviewing as a probe in a perturbation-based neuroimaging approachNIHNational Institute of Mental Health2023 to 2025$2,127,241January 1, 2023October 31, 2027LEE, JUNGHEEreporter.nih.gov
Iron deficits and their relationship with symptoms and cognition in Psychotic Spectrum DisordersNIHNational Institute of Mental Health2023 to 2025$2,125,485April 1, 2023January 31, 2028LAZAR, MARIANAreporter.nih.gov
Digital Strategies to Advance Help-Seeking in Youth at Clinical High Risk for Developing PsychosisNIHNational Institute of Mental Health2024 to 2025$2,123,893August 1, 2024May 31, 2028BIRNBAUM, MICHAEL LEOreporter.nih.gov
Dopamine function, inflammation and connectivity in PTSDNIHNational Institute of Mental Health2021 to 2023$2,122,685August 11, 2020May 31, 2025BREMNER, JAMES DOUGLASreporter.nih.gov
Suicide Circuit Therapeutics: Engaging Novel Targets with Rapid and Individualized MRI-Guided Accelerated TMSNIHNational Institute of Mental Health2023 to 2024$2,117,198May 1, 2023April 30, 2026CAMPRODON, JOAN Areporter.nih.gov
Multimodal Biometrics to Optimize and Scale Decision Support for Depression DBSNIHNational Institute of Neurological Disorders and Stroke2025$2,113,446May 10, 2025April 30, 2030MAYBERG, HELEN Sreporter.nih.gov
The Impact of Alzheimer’s Disease and Related Dementias on Nursing Home Care and Quality for Persons with Serious Mental IllnessNIHNational Institute on Aging2023$2,109,150September 30, 2023August 31, 2026MAUST, DONOVAN Treporter.nih.gov
Implementing mHealth for Schizophrenia in Community Mental Health SettingsNIHNational Institute of Mental Health2021 to 2023$2,106,944January 4, 2019November 30, 2025BEN-ZEEV, DRORreporter.nih.gov
Risk and resilience: Evaluating the multigenerational effect of a psychosocial maternal depression intervention against COVID-19-related stressorsNIHNational Institute of Mental Health2022$2,106,882September 20, 2022September 19, 2025MASELKO, JOANNAreporter.nih.gov
Imaging-guided tDCS therapy in major depressionNIHNational Institute of Mental Health2021 to 2022$2,103,971August 1, 2017July 31, 2024NARR, KATHERINE Lreporter.nih.gov
Individually targeted neuromodulation for contamination-based OCDNIHNational Institute of Mental Health2021 to 2022$2,102,253July 1, 2021June 30, 2024BRENNAN, BRIAN P.reporter.nih.gov
A national birth cohort study of prenatal factors and neurodevelopmental psychiatric disordersNIHNational Institute of Environmental Health Sciences2021 to 2024$2,099,953January 6, 2020October 31, 2025BROWN, ALAN STEWARTreporter.nih.gov
Functional characterization of schizophrenia rare variants using genetically engineered human iPSCsNIHNational Institute of Mental Health2023 to 2025$2,099,952January 1, 2023November 30, 2027LI, PANreporter.nih.gov
Discovery of mGlu receptor PAMs for treatment of schizophreniaNIHNational Institute of Mental Health2021 to 2023$2,099,820February 15, 2019November 30, 2024CONN, P JEFFREYreporter.nih.gov
2/4 Deciphering Mechanisms of ECT Outcomes and Adverse Effects (DECODE)NIHNational Institute of Mental Health2022 to 2025$2,097,342August 1, 2022May 31, 2027ABBOTT, CHRISTOPHER Creporter.nih.gov
Dopaminergic Therapy for Inflammation-Related Anhedonia in DepressionNIHNational Institute of Mental Health2023 to 2025$2,096,259September 1, 2020July 31, 2027FELGER, JENNIFER Creporter.nih.gov
Dynamic imaging-genomic models for characterizing and predicting psychosis and mood disordersNIHNational Institute of Mental Health2021 to 2023$2,086,168May 25, 2019January 31, 2025CALHOUN, VINCE Dreporter.nih.gov
Risk Factors for Psychosis and Mania with Prescription Amphetamine UseNIHNational Institute of Mental Health2021 to 2023$2,082,432June 10, 2020April 30, 2025SHINN, ANN KYUNGAHreporter.nih.gov
4/4-Deciphering Mechanisms of ECT Outcomes and Adverse Effects (DECODE)NIHNational Institute of Mental Health2022 to 2025$2,080,348August 1, 2022May 31, 2027MCCLINTOCK, SHAWN Mreporter.nih.gov
Deriving high-quality evidence from national healthcare databases to improve suicidality detection and treatment outcomes in PTSDNIHNational Institute of Mental Health2023 to 2025$2,075,318December 23, 2022November 30, 2026LAMBERT, CHRISTOPHE G.reporter.nih.gov
Leucine as a Probe of Kynurenine-Induced Glutamate and Neural Circuit Dysfunction in Midlife DepressionNIHNational Institute of Mental Health2023 to 2025$2,074,620July 17, 2023May 31, 2028HAROON, EBRAHIMreporter.nih.gov
Computational phenotyping of face expression in early psychosisNIHNational Institute of Mental Health2023 to 2025$2,074,514April 15, 2023January 31, 2027CORCORAN, CHERYL MARYreporter.nih.gov
The Effects of Statewide Comprehensive Integrated Care for Medicaid Enrollees.NIHNational Institute of Mental Health2021 to 2023$2,074,427July 15, 2020April 30, 2025MCCONNELL, KENNETH JOHNreporter.nih.gov
Medicaid Value Based Payment Models and Healthcare Equity for Adults with Serious Mental IllnessesNIHNational Institute of Mental Health2021 to 2023$2,072,759February 14, 2020November 30, 2024COOK, BENJAMIN LEreporter.nih.gov
Statistical ICA Methods for Analysis and Integration of Multi-dimensional DataNIHNational Institute of Mental Health2021 to 2024$2,066,863September 25, 2014July 31, 2025GUO, YINGreporter.nih.gov
Olfactory and facial markers of developmental risk for psychosis in 22q11 deletion syndromeNIHNational Institute of Mental Health2021 to 2024$2,059,648September 24, 2019January 31, 2025ROALF, DAVID Rreporter.nih.gov
Functional genomic resource and integrative model of dopaminergic circuitry associated with psychiatric diseaseNIHNational Institute on Drug Abuse2021 to 2023$2,057,596May 1, 2019February 28, 2025AKBARIAN, SCHAHRAMreporter.nih.gov
THE SENDEP STUDY: LINKING MOLECULAR SENESCENCE CHANGES TO DEPRESSION AND COGNITIVE IMPAIRMENT IN LATE LIFENIHNational Institute of Mental Health2021 to 2023$2,057,113February 15, 2019December 31, 2024DINIZ, BRENO SATLERreporter.nih.gov
Cognitive Enhancement for Persistent Negative Symptoms in SchizophreniaNIHNational Institute of Mental Health2021 to 2023$2,055,727September 1, 2019June 30, 2025EACK, SHAUN Mreporter.nih.gov
Bringing Health Home: Evaluation of a Residential-based Telehealth Care Coordination InterventionNIHNational Institute of Mental Health2021 to 2023$2,054,790September 14, 2021August 31, 2025UNICK, GEORGE JAYreporter.nih.gov
Targeting adolescent depression symptoms using network-based real-time fMRI neurofeedback and mindfulness meditationNIHNational Institute of Mental Health2023 to 2024$2,051,305March 21, 2023February 28, 2026WHITFIELD-GABRIELI, SUSANreporter.nih.gov
Impact of Recreational and Medical Marijuana legalization on cannabis use disorders, serious mental illness, and mortality outcomes among Medicaid enrolled youthNIHNational Institute on Drug Abuse2023 to 2025$2,046,397August 1, 2023June 30, 2028FONTANELLA, CYNTHIA ANNreporter.nih.gov
Ecological Assessment of Proximal Risk Factors for Suicide During Care TransitionsNIHNational Institute of Mental Health2023 to 2025$2,046,280January 1, 2023October 31, 2027ARMEY, MICHAEL Freporter.nih.gov
Real-time fMRI Neurofeedback as a Tool to Mitigate Auditory Hallucinations in Patients with SchizophreniaNIHNational Institute of Mental Health2022 to 2023$2,043,760June 1, 2018June 30, 2025NIZNIKIEWICZ, MARGARET Areporter.nih.gov
Health Promotion in the Prevention of Anxiety and Depression: The Happy Older Latinos are Active (HOLA Study)NIHNational Institute on Minority Health and Health Disparities2021 to 2023$2,039,948May 9, 2019July 31, 2025JIMENEZ, DANIEL ENRIQUEreporter.nih.gov
Computerized detection and internet-based treatment of common mental disorders among college students in two Latin American LMICsNIHNational Institute of Mental Health2021 to 2024$2,037,463July 1, 2020June 30, 2025BENJET, CORINA L.reporter.nih.gov
1/5 Clinical Outcome Prediction of Psychosis from EHRs (COPPER)NIHNational Institute of Mental Health2024 to 2025$2,037,111September 5, 2024May 31, 2029KUSHNER, STEVEN Areporter.nih.gov
Neurocomputational mechanisms of antidepressant placebo effectsNIHNational Institute of Mental Health2021 to 2024$2,034,314April 9, 2020March 31, 2026PECINA, MARTAreporter.nih.gov
Prefrontal microcircuitry and cognition in schizophreniaNIHNational Institute of Mental Health2021 to 2023$2,029,326September 30, 1988November 30, 2025LEWIS, DAVID Areporter.nih.gov
Multidimensional aging trajectories in mid to late-life psychosis (MAP)NIHNational Institute of Mental Health2024 to 2025$2,026,181December 15, 2023October 31, 2028LEE, JUNGHEEreporter.nih.gov
Neural mechanisms of perceptual abnormalities and their malleability in body dysmorphic disorderNIHNational Institute of Mental Health2021 to 2025$2,023,425July 23, 2020May 31, 2027FEUSNER, JAMIEreporter.nih.gov
Target Engagement During Social Reward Psychotherapy for Mid- and Late-Life Suicidality: A Precision Imaging TrialNIHNational Institute of Mental Health2023 to 2025$2,018,084July 21, 2023April 30, 2028SOLOMONOV, NILIreporter.nih.gov
Multimodal Assessment of Near-term Risk Processes for Suicide Ideation and BehaviorNIHNational Institute of Mental Health2021 to 2023$2,006,802January 5, 2019October 31, 2025SCOTT, LORI Nreporter.nih.gov
Uncovering the Risk Architecture of Suicidal Behaviors: a Representative Sample at High RiskNIHNational Institute of Mental Health2021 to 2023$2,005,331August 2, 2019June 30, 2025HOVEN, CHRISTINA W.reporter.nih.gov
Neural substrates of deficits in naturalistic social cognition in schizophreniaNIHNational Institute of Mental Health2021 to 2023$2,005,192July 1, 2020April 30, 2026PATEL, GAURAV Hreporter.nih.gov
Mechanisms of Serotonin Modulation of PanicNIHNational Institute of Mental Health2021 to 2024$2,002,964March 12, 2020December 31, 2025TRUITT, WILLIAM ANTHONYreporter.nih.gov
Psychosis-related Physiological and Neuronal Phenotypes in 22q11 Deletion SyndromeNIHNational Institute of Mental Health2021 to 2023$1,997,858September 1, 2019September 30, 2024CUBELLS, JOSEPH F.reporter.nih.gov
Personalized Deep Learning Models of Rapid Changes in Major Depressive Disorder Symptoms using Passive Sensor Data from Smartphones and Wearable DevicesNIHNational Institute of Mental Health2021 to 2024$1,997,827August 6, 2020May 31, 2026JACOBSON, NICHOLAS CHARLESreporter.nih.gov
The Etiology of Risk: Alcohol Use Disorder and Suicidal BehaviorNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$1,991,046May 20, 2019August 31, 2029EDWARDS, ALEXIS Creporter.nih.gov
Use of alpha-frequency deep transcranial interference stimulation (tIS) to understand and modify temporal dynamics of face emotion recognition and social/affective function.NIHNational Institute of Mental Health2024 to 2025$1,982,292July 2, 2024February 29, 2028JAVITT, DANIEL C.reporter.nih.gov
Magnetic Resonance-guided Focused Ultrasound Ablation of the Anterior Thalamus as a Novel Treatment Paradigm for AnxietyNIHNational Institute of Mental Health2022 to 2025$1,980,503March 1, 2022December 31, 2026PHAN, K. LUANreporter.nih.gov
Tourette Syndrome genetics and neuroimaging international collaborative studyNIHNational Institute of Mental Health2022 to 2025$1,977,219March 4, 2022December 31, 2026PASCHOU, PERISTERAreporter.nih.gov
Electroconvulsive therapy amplitude titration for improved clinical outcomes in late-life depressionNIHNational Institute of Mental Health2023 to 2025$1,976,307February 4, 2021January 31, 2027ABBOTT, CHRISTOPHER Creporter.nih.gov
Investigating the Systems Genetics of the Patterns of Polysubstance Abuse and AddictionNIHNational Institute on Drug Abuse2021 to 2023$1,975,165February 15, 2019January 31, 2025POLIMANTI, RENATOreporter.nih.gov
Air Pollution and Male-Biased Psychiatric DisordersNIHNational Institute of Environmental Health Sciences2021 to 2025$1,972,362September 18, 2020June 30, 2026CORY-SLECHTA, DEBORAH Areporter.nih.gov
Global studies into the Genetic Architecture of the Brain's White Matter Network through Harmonized and Coordinated Analyses in the ENIGMA-ConsortiumNIHNational Institute of Mental Health2023 to 2025$1,970,498September 1, 2023June 30, 2028JAHANSHAD, NEDAreporter.nih.gov
Development of Kv3.1 potentiators for correcting fast-spiking-interneuron hypofunction in schizophrenia and autism spectrum disorderNIHNational Institute of Mental Health2023 to 2025$1,969,171August 1, 2023May 31, 2027DENTON, JEROD S.reporter.nih.gov
An Efficacy Trial of Mobile Technology for Reducing and Preventing Adolescent SuicideNIHNational Institute of Mental Health2023 to 2025$1,968,083February 15, 2021March 31, 2027SIMON, PATRICIAreporter.nih.gov
The Developmental Psychopathology of Suicidal Ideations and Cognitions in ChildhoodNIHNational Institute of Mental Health2021 to 2023$1,963,703May 15, 2019February 28, 2025LUBY, JOAN L.reporter.nih.gov
Effectiveness Research for Common Mental Disorders in Low and Middle Income Countries: A sequential, multiple assignment randomized trial for non-specialist treatment strategies in KenyaNIHNational Institute of Mental Health2021 to 2023$1,962,290June 1, 2019June 30, 2025MEFFERT, SUSAN M.reporter.nih.gov
Early Psychosis Intervention Network (EPINET) Data Coordinating CenterNIHNational Institute of Mental Health2025$1,960,903September 1, 2025August 31, 2030ROSENBLATT, ABRAMreporter.nih.gov
Reducing Adolescent Suicide Risk: Safety, Efficacy, and Connectome Phenotypes of Intravenous KetamineNIHNational Institute of Mental Health2021 to 2023$1,958,386September 15, 2020April 30, 2025BLOCH, MICHAEL Hreporter.nih.gov
A Randomized, Controlled Trial of Crisis Intervention Team (CIT) Mental Health Training for Police OfficersNIHNational Institute of Mental Health2023 to 2025$1,957,440January 1, 2023December 31, 2026COMPTON, MICHAEL Treporter.nih.gov
A randomized controlled trial of a preventive behavioral intervention for young adults with psychotic experiencesNIHNational Institute of Mental Health2024 to 2025$1,951,537August 1, 2024May 31, 2029HOLT, DAPHNE Jreporter.nih.gov
Multi-modal assessment of GABA function in psychosisNIHNational Institute of Mental Health2021 to 2023$1,949,466September 1, 2019June 30, 2025TAYLOR, STEPHAN Freporter.nih.gov
Cognitive Reappraisal Training Targeting Emotion Circuits As a Therapeutic Intervention in Borderline PatientsNIHNational Institute of Mental Health2021 to 2022$1,947,668July 1, 2021June 30, 2024KOENIGSBERG, HAROLD Wreporter.nih.gov
An examination of psychomotor disturbance in current and remitted MDD: An RDoC StudyNIHNational Institute of Mental Health2021 to 2023$1,938,593April 8, 2019March 31, 2025SHANKMAN, STEWART AARONreporter.nih.gov
Global Deep Learning Initiative to Understand Outcomes in Major DepressionNIHNational Institute of Mental Health2023 to 2025$1,933,396June 1, 2023March 31, 2028THOMPSON, PAUL Mreporter.nih.gov
1/3 Understanding PTSD through Postmortem Targeted Brain Multi-omicsNIHNational Institute of Mental Health2021 to 2025$1,932,852July 25, 2018February 28, 2030NEMEROFF, CHARLES Breporter.nih.gov
Effects of a Prenatal Depression Preventive Intervention on Parenting and Young Children's Self-Regulation and Functioning (EPIC)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,925,858August 7, 2019May 31, 2024TANDON, SHIV DARIUSreporter.nih.gov
CBTpro: Scaling up CBT for psychosis using simulated patients and spoken language technologiesNIHNational Institute of Mental Health2021 to 2023$1,923,480March 11, 2020April 30, 2025KOPELOVICH, SARAH LYNNreporter.nih.gov
Interpersonal Stress, Social Media, and Risk for Adolescent Suicidal Thoughts and BehaviorsNIHNational Institute of Mental Health2023 to 2024$1,921,580September 14, 2023July 31, 2028MELHEM, NADINE M.reporter.nih.gov
3/7-PsycheMERGE: Advancing Precision PsychiatryNIHNational Institute of Mental Health2024 to 2025$1,919,498September 16, 2024May 31, 2029PETERSON, ROSEANN ELIZABETHreporter.nih.gov
Construction of the integrated human cortical organoids to investigate neurodevelopmental disordersNIHNational Institute of Mental Health2021 to 2023$1,916,931September 9, 2019July 31, 2025PARK, IN-HYUNreporter.nih.gov
Antipsychotics and the Risk of Unexpected Death in Children and YouthNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,907,983January 1, 2019December 31, 2024RAY, WAYNE Areporter.nih.gov
Sex and pubertal influences on developmental trajectories of brain networks involved in schizophreniaNIHNational Institute of Mental Health2021 to 2025$1,906,847March 1, 2021December 31, 2026GUYER, AMANDA Ereporter.nih.gov
VoiceLove: NICU Utilization of Remote voice Technology to improve mateRnal Experience (NURTURE)NIHNational Institute of Mental Health2024 to 2025$1,905,381April 12, 2024March 31, 2027OSMUNDSON, SARAH SCHEIDERICHreporter.nih.gov
Comprehensive analysis of genetic pleiotropy in eleven neuropsychiatric disordersNIHNational Institute of Mental Health2021 to 2024$1,904,829December 18, 2019October 31, 2025LEE, PHIL H.reporter.nih.gov
Effectiveness of a Synergistic, Neuroplasticity-Based intervention for Rapid and Durable Suicide Risk ReductionNIHNational Institute of Mental Health2021 to 2023$1,902,116September 15, 2020August 31, 2025PRICE, REBECCAreporter.nih.gov
Prevention of perinatal depression among at-risk individuals through integration of a multimedia, web-based intervention within the healthcare systemNIHNational Institute of Nursing Research2022$1,901,661September 23, 2022August 31, 2025LATENDRESSE, GWEN Areporter.nih.gov
Diversity Supplement: Neural mechanisms of meditation training in healthy and depressed adolescents: An MRI connectome studyNIHNational Center for Complementary & Integrative Health2022 to 2024$1,900,768July 1, 2022August 31, 2025YANG, TONY TUNG-Ireporter.nih.gov
Dissecting and modifying temporal dynamics underlying major depressive disorderNIHNational Institute of Mental Health2021 to 2023$1,899,819September 1, 2019June 30, 2024DZIRASA, KAFUIreporter.nih.gov
Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk in Adolescents at Clinical High Risk for PsychosisNIHNational Institute of Mental Health2023 to 2025$1,897,549May 15, 2021April 30, 2027CARRION, RICARDOreporter.nih.gov
Mapping heterogeneity of brain microstructural abnormalities in psychiatric disorders with normative modellingNIHNational Institute of Mental Health2023 to 2025$1,896,067September 1, 2023July 31, 2028KRAGULJAC, NINA VANESSAreporter.nih.gov
Biotyping Mood Health in Late Adolescence: Neurocognitive Dimensions and Stress PathwaysNIHNational Institute of Mental Health2021 to 2023$1,895,671July 3, 2020April 30, 2026KAISER, ROSELINDE Hreporter.nih.gov
Investigating relationships between problematic social media use and binge-eating disorder to inform precision guidance for adolescentsNIHNational Institute of Mental Health2025$1,894,979September 15, 2023June 30, 2028NAGATA, JASON Mreporter.nih.gov
Reducing Overdose and Suicide Risk in Individuals with OUD and Co-occurring DisordersNIHNational Institute on Drug Abuse2023 to 2025$1,892,256June 15, 2023March 31, 2028WATKINS, KATHERINE Ereporter.nih.gov
Developmental effects of antenatal exposure to antipsychoticsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,888,536June 1, 2023April 30, 2028ROBAKIS, THALIA Kreporter.nih.gov
School based stepped care TrEatment for adolescent depression in Pakistan- a Sequential Multiple Assignment Randomized Trial (SMART-STEP)NIHNational Institute of Mental Health2022 to 2025$1,879,310September 14, 2022June 30, 2027HAMDANI, SYED USMANreporter.nih.gov
Effects of prenatal maternal depression and antidepressant exposures on offspring neurodevelopmental trajectories: A birth cohort studyNIHNational Institute of Mental Health2021 to 2023$1,879,041March 8, 2019January 31, 2025TALATI, ARDESHEERreporter.nih.gov
Maternal Inflammation During Pregnancy: Clinical and Neurocognitive Outcomes in Adult OffspringNIHNational Institute of Mental Health2021 to 2023$1,871,310July 1, 2019March 31, 2025ELLMAN, LAUREN Mreporter.nih.gov
Ketamine Treatment of Youth Suicide Attempters for Fast Reduction of Severe Suicide Risk and Facilitation of Long-term Collaborative Clinical Engagement: A Randomized Placebo Controlled TrialNIHNational Institute of Mental Health2021 to 2025$1,869,024September 15, 2020August 31, 2026FALCONE, TATIANAreporter.nih.gov
Genetic Basis of the Risk and Consequences of Cannabis Exposure in HumansNIHNational Institute on Drug Abuse2023 to 2025$1,866,314September 30, 2023July 31, 2028D'SOUZA, DEEPAK CYRILreporter.nih.gov
Training in Schizophrenia and Psychotic Disorders: From Animal Models to PatientsNIHNational Institute of Mental Health2021 to 2024$1,850,218August 1, 1988March 13, 2025KELLENDONK, CHRISTOPHreporter.nih.gov
MRI Markers of Feedback Timing during Learning in Individuals with TBI with and without Clinical DepressionNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,849,868April 1, 2021January 31, 2027DOBRYAKOVA, EKATERINAreporter.nih.gov
Biological Risk Factors for the Prospective Development of Alcohol Use Disorders in Young Adults with Bipolar Disorder and Typically Developing Young AdultsNIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2025$1,847,726March 10, 2023February 29, 2028LIPPARD, ELIZABETH THOMAS COXreporter.nih.gov
1/2 A Brief Automated Neurocognitive Training to Enhance the Real-World Impact of Ketamine's Rapid Antidepressant EffectNIHNational Institute of Mental Health2024 to 2025$1,847,505July 5, 2024May 31, 2029PRICE, REBECCAreporter.nih.gov
1/5 - Selective Antipsychotic Response to Clozapine in B-SNIP Biotype-1 (Clozapine)NIHNational Institute of Mental Health2021 to 2025$1,844,625May 1, 2021April 30, 2027TAMMINGA, CAROL Areporter.nih.gov
The Effectiveness and Cost-Effectiveness of Implementing Evidence-Based Depression Treatment within the TB Care Platform in South Africa: A Hybrid Effectiveness-Implementation TrialNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,844,087September 1, 2025August 31, 2028SWEETLAND, ANNIKA CLAIREreporter.nih.gov
Potentiate Cav3.3 To Treat Cognitive Deficits Associated with Impaired Sleep SpindleNIHNational Institute of Mental Health2022 to 2023$1,836,115September 1, 2022June 30, 2023PAN, JEN QIANreporter.nih.gov
The GEN-BLIP Study (GENetics of BipoLar Disorder In Pakistan)NIHNational Institute of Mental Health2022 to 2024$1,833,714July 7, 2020April 30, 2026KNOWLES, JAMES Areporter.nih.gov
Deconvoluting Polypharmacologic Contributions of Rapidly-Acting AntidepressantsNIHNational Institute of Mental Health2021 to 2024$1,832,928April 16, 2020January 31, 2025WENTHUR, CODY JAMESreporter.nih.gov
Patient-derived Models of Synaptic Pruning in SchizophreniaNIHNational Institute of Mental Health2021 to 2023$1,832,595July 19, 2019April 30, 2025PERLIS, ROY H.reporter.nih.gov
Sleep to Reduce Incident Depression Effectively in Peripartum - (STRIDE P)NIHNational Institute of Mental Health2024 to 2025$1,823,203August 1, 2024February 29, 2028DRAKE, CHRISTOPHER Lreporter.nih.gov
2/5-Clozapine Response and Biomarker Correlates in Low-IEA Biotype-1NIHNational Institute of Mental Health2021 to 2025$1,822,500May 1, 2021April 30, 2027GERSHON, ELLIOT Sreporter.nih.gov
Pathways from Chronic Prescription Opioid Use to New Onset Mood DisorderNIHNational Institute on Drug Abuse2021 to 2023$1,821,346April 15, 2019January 31, 2025SCHERRER, JEFFREY F.reporter.nih.gov
Optimizing digital health technologies to improve therapeutic skill use and acquisitionNIHNational Institute of Mental Health2022 to 2024$1,820,380April 1, 2022February 28, 2026MANASSE, STEPHANIEreporter.nih.gov
A Randomized Controlled Trial of Sequential Bilateral Accelerated Theta Burst Stimulation in Adolescents with Suicidal Ideation Associated with Major Depressive DisorderNIHNational Institute of Mental Health2021 to 2023$1,817,858September 10, 2020August 31, 2025CROARKIN, PAUL Ereporter.nih.gov
Molecular dissection of synaptic dysfunction in mental disordersNIHNational Institute of Mental Health2021 to 2024$1,815,127April 1, 2020January 31, 2026PAK, CHANGHUIreporter.nih.gov
3/5 Selective Antipsychotic Response to Clozapine in B-SNIP Biotype-1 (CLOZAPINE)NIHNational Institute of Mental Health2021 to 2025$1,814,390May 1, 2021April 30, 2027PEARLSON, GODFREY Dreporter.nih.gov
Cognitive control targets for the treatment of obsessive compulsive disorder in young childrenNIHNational Institute of Mental Health2023 to 2024$1,805,208September 11, 2023August 31, 2025MARSH, RACHELreporter.nih.gov
Prodromal Inventory for Negative Symptoms (PINS): A Development and Validation StudyNIHNational Institute of Mental Health2021 to 2023$1,801,407March 1, 2019November 30, 2025STRAUSS, GREGORY Preporter.nih.gov
2/2 A brief automated neurocognitive training to enhance the real-world impact of ketamine's rapid antidepressant effectNIHNational Institute of Mental Health2024 to 2025$1,797,606July 18, 2024May 31, 2029O'BRIEN, BRITTANYreporter.nih.gov
Characterization of schizophrenia liability genes in models of human microglial synaptic pruningNIHNational Institute of Mental Health2023 to 2025$1,793,419July 12, 2023March 31, 2028SHERIDAN, STEVEN Dreporter.nih.gov
Stress-immune mechanisms for people living with HIV, CUD and DepressionNIHNational Institute on Drug Abuse2024 to 2025$1,790,616September 30, 2024May 31, 2029XU, KEreporter.nih.gov
Quantitative Language and Facial Expression Phenotyping of Chronic PainNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$1,787,594September 23, 2022July 31, 2027GEHA, PAULreporter.nih.gov
Integrative approaches to identification and interpretation of genes underlying psychiatric disordersNIHNational Institute of Mental Health2021 to 2023$1,787,019August 10, 2020May 31, 2025HAN, SHIZHONGreporter.nih.gov
Understanding Schizophrenia Risk Mechanisms Via Multimodal Analysis of Patient-derived Neurons and 3D Cortical Organoids and Correlation with Clinical and Cognitive PhenotypesNIHNational Institute of Mental Health2024 to 2025$1,786,771August 7, 2024April 30, 2026MAHER, BRADY Jreporter.nih.gov
Epitranscriptomic Mapping of Novel N6-Adenosine-based RNA Methylation in MDD BrainNIHNational Institute of Mental Health2021 to 2023$1,776,909July 16, 2019April 30, 2025DWIVEDI, YOGESHreporter.nih.gov
1/2 Large-scale, single-cell characterization of molecular and cellular networks of mood regulation circuitry in major depressive disorderNIHNational Institute of Mental Health2024 to 2025$1,776,475September 7, 2024May 31, 2029HYDE, THOMAS MICHAELreporter.nih.gov
Transdiagnostic Multimodal 7 Tesla MRI of the Locus Coeruleus in Human Pathological AnxietyNIHNational Institute of Mental Health2021 to 2023$1,776,343March 15, 2019June 30, 2024MURROUGH, JAMES WARRENreporter.nih.gov
FastPlex: A Fast Deep Learning Segmentation Method for Accurate Choroid Plexus MorphometryNIHNational Institute of Mental Health2023 to 2025$1,761,887June 1, 2023June 30, 2025LIZANO, PAULO Lreporter.nih.gov
1/2 Trans-ancestry genomic analysis of obsessive-compulsive disorderNIHNational Institute of Mental Health2021 to 2025$1,761,753September 1, 2021June 30, 2027CROWLEY, JAMES JOSEPHreporter.nih.gov
Psychosis Genetics Research in Africa: Building Capacity by Investing in PeopleNIHNational Institute of Mental Health2021 to 2023$1,754,766September 1, 2019June 30, 2025KOENEN, KARESTAN Creporter.nih.gov
Ketogenic Diet in Weight Recovered Anorexia Nervosa to Target Metabolism and Normalize Persistent Eating Disorder PsychopathologyNIHNational Institute of Mental Health2024 to 2025$1,752,406July 15, 2024May 31, 2027FRANK, GUIDO KWreporter.nih.gov
African Ancestry Genomic Psychiatry CohortNIHNational Institute of Mental Health2021$1,751,495July 1, 2021June 30, 2022PATO, MICHELE Treporter.nih.gov
Cardiovascular Disease Risk Factors in At-Risk Hispanic Women following Pregnancy ComplicationsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$1,747,777September 1, 2022August 31, 2027CHASAN-TABER, LISAreporter.nih.gov
Developing an app-based behavioral intervention to help depressed individuals return to workNIHNational Institute of Mental Health2021 to 2023$1,739,340September 20, 2022December 31, 2024LEVIT, ALEXANDRAreporter.nih.gov
Modeling Physiology and Behavior of Veterans to Avert Opioid Related Mortality Through Timely InterventionNIHNational Institute on Drug Abuse2022 to 2025$1,737,174September 15, 2022January 31, 2027GORDON, ELLIEreporter.nih.gov
Developing rumination-focused treatment to reduce risk for depression recurrence (RDR) in adolescenceNIHNational Institute of Mental Health2023 to 2024$1,730,960August 1, 2018April 30, 2026LANGENECKER, SCOTT Areporter.nih.gov
Mapping links between real-world diversity, positive emotion, and neural dynamics in anhedoniaNIHNational Institute of Mental Health2023 to 2025$1,730,956July 1, 2023April 30, 2028HELLER, AARON Sreporter.nih.gov
MomNet: Development of a Coach-Training Program for an Empirically Supported, Guided ehealth Intervention for Depressed MothersNIHNational Institute of Mental Health2023 to 2024$1,730,251August 3, 2020March 31, 2026SMITH, DAVID RANDOLPHreporter.nih.gov
Combining data sources to identify effect moderation for personalized mental health treatmentNIHNational Institute of Mental Health2021 to 2024$1,730,235August 19, 2021May 31, 2026STUART, ELIZABETH A.reporter.nih.gov
Mental Health and Cognition in HIV Infection in Rakai UgandaNIHNational Institute of Mental Health2021 to 2023$1,729,101August 22, 2019June 30, 2025RUBIN, LEAH HELANEreporter.nih.gov
Amygdala rtfMRI Neurofeedback for Treatment Resistant DepressionNIHNational Institute of Mental Health2022 to 2024$1,718,726August 1, 2018April 30, 2026YOUNG, KYMreporter.nih.gov
Clarifying the association of depressive symptoms with cortico-limbic tau, cerebral blood flow, neurodegeneration, and longitudinal cognitive decline in individuals with mild cognitive impairmentNIHNational Institute on Aging2025$1,711,908April 15, 2025March 31, 2030MACKIN, ROBERT SCOTTreporter.nih.gov
Specialized pro-resolving lipid mediators and treatment resistant depressionNIHNational Center for Complementary & Integrative Health2023 to 2025$1,708,287April 10, 2023March 31, 2026KINKEAD, BECKY Lreporter.nih.gov
Longitudinal trajectories in treated and untreated schizophreniaNIHNational Institute of Mental Health2021 to 2023$1,706,634September 16, 2021July 31, 2027YANG, LAWRENCE Hreporter.nih.gov
Improving Preschool Outcomes by Addressing Maternal Depression in Head StartNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$1,706,365January 1, 2022December 31, 2026SILVERSTEIN, MICHAELreporter.nih.gov
EMERGE: Ecological Momentary Evaluation of Responses to Gain/Loss and EmotionsNIHNational Institute of Mental Health2022 to 2025$1,698,012February 15, 2022December 31, 2026DIXON-GORDON, KATHERINE LEEreporter.nih.gov
Noninvasive modulation of deep brain circuits for treatment-resistant depressionNIHNational Institute of Mental Health2024 to 2025$1,689,511June 1, 2024May 31, 2027MICKEY, BRIAN JAMESreporter.nih.gov
Dynamic Decision Support Tools for Precision Treatment-Resistant Depression CareNIHNational Institute of Mental Health2025$1,688,034September 1, 2025August 31, 2027WANG, PHILIP Sreporter.nih.gov
Phenotypic and genetic architecture of OCD in African AmericansNIHNational Institute of Mental Health2024 to 2025$1,684,654May 10, 2024February 28, 2029GRICE, DOROTHY Ereporter.nih.gov
Progression of Social Cognitive Deficits in Mid- and Late-Life Schizophrenia Spectrum DisordersNIHNational Institute of Mental Health2024 to 2025$1,681,147December 15, 2023October 31, 2028TSO, IVY FEIreporter.nih.gov
Evaluating the Impact of Restrictive Eating Disorders on White Matter DevelopmentNIHNational Institute of Mental Health2022 to 2025$1,680,000September 1, 2022June 30, 2027KUBICKI, MAREKreporter.nih.gov
Ketamine to reduce postpartum depression and pain after cesarean deliveryNIHNational Institute of Mental Health2023 to 2025$1,677,192July 1, 2023February 26, 2026LIM, GRACEreporter.nih.gov
Predicting the onset of depression in at-risk adolescents from endophenotype profilesNIHNational Institute of Mental Health2021 to 2024$1,670,023December 11, 2018October 31, 2025WEBB, CHRISTIAN ANTHONYreporter.nih.gov
Application of Advanced Quantitative Methods to Schizophrenia ResearchNIHNational Institute of Mental Health2021 to 2023$1,665,413January 15, 2021November 30, 2024DWORK, ANDREW Jreporter.nih.gov
ENIGMA-COINSTAC: Advanced Worldwide Transdiagnostic Analysis of Valence System Brain CircuitNIHNational Institute of Mental Health2022 to 2023$1,663,302August 2, 2019May 31, 2025TURNER, JESSreporter.nih.gov
Development and Randomized Clinical Trial of an App-based Intervention to Reduce Postpartum Depression in High-Risk WomenNIHNational Institute of Mental Health2022 to 2024$1,660,962March 24, 2017February 28, 2026FOX, DEBRA Lreporter.nih.gov
Translational studies in humans and mice to test a circuit-level computational model of auditory hallucinations..NIHNational Institute of Mental Health2024 to 2025$1,659,265August 13, 2024May 31, 2029HORGA, GUILLERMOreporter.nih.gov
Constructing the subjective value of food in Anorexia NervosaNIHNational Institute of Mental Health2023 to 2025$1,656,420September 14, 2023July 31, 2028BAKKOUR, AKRAMreporter.nih.gov
Using fMRI of Autobiographical Memory Recall to Determine Risk and Resilience Endophenotypes in Familial Major Depressive DisorderNIHNational Institute of Mental Health2021 to 2023$1,654,284April 12, 2019January 31, 2026YOUNG, KYMreporter.nih.gov
Examining racial disparities in fatal overdose, self-harm, and perpetrating assaults following law enforcement-mediated involuntary commitmentNIHNational Institute on Minority Health and Health Disparities2023 to 2025$1,653,293July 15, 2023December 31, 2026ROSEN, DAVID Lreporter.nih.gov
Ascertaining Neurocircuitry to Enhance Neuromodulation Development ASCENDNIHNational Institute of Mental Health2021 to 2023$1,653,181April 5, 2019February 28, 2026MCCLINTOCK, SHAWN Mreporter.nih.gov
Targeting Arc to Improve Cognitive Deficits in Psychotic DisordersNIHNational Institute of Mental Health2024 to 2025$1,651,680July 8, 2024February 28, 2029KARMACHARYA, RAKESHreporter.nih.gov
Efficacy of kTMP, a novel non-invasive brain stimulation method, for the treatment of anhedonia patients.NIHNational Institute of Mental Health2025$1,651,499August 18, 2025July 31, 2028LABRUNA, LUDOVICAreporter.nih.gov
Reward, Salience and Value Processing in Youths at Risk for Psychosis: The RSVP StudyNIHNational Institute of Mental Health2024 to 2025$1,650,098March 1, 2024December 31, 2028WALTZ, JAMES Areporter.nih.gov
1/2 Harnessing Hormonal Variation to Probe Neural Mechanisms and Optimize CBT Outcomes for OCDNIHNational Institute of Mental Health2021 to 2025$1,649,302September 1, 2021June 30, 2028SIMPSON, HELEN BLAIRreporter.nih.gov
Positive Valence Systems and Manic Symptom Trajectories in Adolescent Depression - SupplementNIHNational Institute of Mental Health2021 to 2022$1,648,973December 15, 2017October 31, 2022LADOUCEUR, CECILE D.reporter.nih.gov
A Transdiagnostic Study of Emotional Impulsivity in Suicidal Ideation and BehaviorNIHNational Institute of Mental Health2024 to 2025$1,647,519August 1, 2024May 31, 2029HOPTMAN, MATTHEW Jreporter.nih.gov
Depression in Older Asthmatics: Understanding Inflammatory and Behavioral PathwaysNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,645,945June 1, 2019April 30, 2024WISNIVESKY, JUAN Preporter.nih.gov
Integrated, cell type specific functional genomics analyses of regulatory sequence elements and their dynamic interaction networks in neuropsychiatric brain tissuesNIHNational Institute of Mental Health2023$1,643,250June 20, 2019March 31, 2025URBAN, ALEXANDER ECKEHARTreporter.nih.gov
Modulating spinal interoceptive pathways to evaluate their role and therapeutic potential in MDD symptomatic domainsNIHNational Institute of Mental Health2024 to 2025$1,638,775August 15, 2024July 31, 2027ROMO-NAVA, FRANCISCOreporter.nih.gov
Multisystem Stress Response Biotypes: Deriving Novel Physiological and Neural Risk Factors for Anhedonia in AdolescenceNIHNational Institute of Mental Health2024 to 2025$1,636,030July 12, 2024June 30, 2029BELGER, AYSENILreporter.nih.gov
2/7 PsycheMERGE: Advancing Precision PsychiatryNIHNational Institute of Mental Health2024 to 2025$1,635,902September 1, 2024May 31, 2029SMOLLER, JORDAN Wreporter.nih.gov
Cyclical deficits in emotion regulation as a risk factor for alcohol misuse in premenopausal femalesNIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2025$1,635,157May 1, 2023February 29, 2028PANG, RAINAreporter.nih.gov
Developmental Trajectories of Brain Network Strength and Flexibility: Relationship to Risk, Onset and Course of Depression and Self-Harm in YouthNIHNational Institute of Mental Health2021 to 2024$1,631,675June 1, 2021March 31, 2025CULLEN, KATHRYN REGANreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Yale UniversityNew Haven, CT58$171 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA101$143.8 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY63$109.4 million0$0
Massachusetts General HospitalBoston, MA64$81.3 million0$0
New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INCNew York, NY52$74.6 million0$0
University of California Los AngelesLos Angeles, CA45$72.6 million0$0
Brigham and Women's HospitalBoston, MA24$65.1 million0$0
University of California, San FranciscoSan Francisco, CA35$64 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC45$54.2 million0$0
University of California, San DiegoLa Jolla, CA45$51.7 million0$0
Columbia University Health SciencesNew York, NY39$44.7 million0$0
Mclean HospitalBelmont, MA39$43.2 million0$0
University of PennsylvaniaPhiladelphia, PA31$37 million0$0
Vanderbilt University Medical CenterNashville, TN18$35.8 million0$0
Johns Hopkins UniversityBaltimore, MD31$35.4 million0$0
Washington UniversitySaint Louis, MO35$35.4 million0$0
University of Maryland BaltimoreBaltimore, MD29$34.7 million0$0
Ohio State UniversityColumbus, OH13$32.4 million0$0
Broad Institute, Inc.Cambridge, MA9$31.7 million0$0
University of WashingtonSeattle, WA21$30 million0$0
New York University School of MedicineNew York, NY22$29.3 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ13$28.3 million0$0
Emory UniversityAtlanta, GA30$27.8 million0$0
Weill Medical Coll of Cornell UnivNew York, NY21$25.7 million0$0
Duke UniversityDurham, NC16$24.3 million0$0
Stanford UniversityStanford, CA24$24.2 million0$0
University of MelbourneMelbourne1$24.1 million0$0
University of Alabama at BirminghamBirmingham, AL15$22.5 million0$0
Baylor College of MedicineHouston, TX14$21.9 million0$0
Feinstein Institute for Medical ResearchManhasset, NY22$21.1 million0$0
Albert Einstein College of MedicineBronx, NY3$20.8 million0$0
Lieber Institute, Inc.Baltimore, MD12$20.7 million0$0
University of Michigan at Ann ArborAnn Arbor, MI15$19.9 million0$0
University of UtahSalt Lake City, UT12$19.9 million0$0
SUNY at Stony BrookStony Brook, NY18$19.6 million0$0
Virginia Commonwealth UniversityRichmond, VA17$18.2 million0$0
Ut Southwestern Medical CenterDallas, TX15$17.9 million0$0
University of California-IrvineIrvine, CA8$17.2 million0$0
Boston Children's HospitalBoston, MA7$16.5 million0$0
University of Southern CaliforniaLos Angeles, CA20$15.4 million0$0
University of Texas at AustinAustin, TX11$15.1 million0$0
Michigan State UniversityEast Lansing, MI7$14.4 million0$0
Northwestern University at ChicagoChicago, IL16$13.9 million0$0
University of MinnesotaMinneapolis, MN20$12.9 million0$0
University of California at DavisDavis, CA12$12.8 million0$0
University of IowaIowa City, IA11$12.3 million0$0
Beth Israel Deaconess Medical CenterBoston, MA13$12.2 million0$0
Temple Univ of the CommonwealthPhiladelphia, PA11$11.8 million0$0
Georgia State UniversityAtlanta, GA7$11.5 million0$0
University of RochesterRochester, NY14$10.7 million0$0
Butler Hospital (providence, Ri)Providence, RI8$10.6 million0$0
Kaiser Foundation Research InstituteOakland, CA6$10.3 million0$0
Laureate Institute for Brain ResearchTulsa, OK8$9.6 million0$0
Rand CorporationSanta Monica, CA5$9.6 million0$0
University of Illinois at ChicagoChicago, IL11$9.4 million0$0
Brown UniversityProvidence, RI8$9.3 million0$0
Vanderbilt UniversityNashville, TN11$9.2 million0$0
University of Wisconsin-MilwaukeeMilwaukee, WI4$9.1 million0$0
Centre for Addiction and Mental HealthToronto11$9 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA8$8.8 million0$0
University of Georgia Research Foundation IncAthens, GA10$8.7 million0$0
University of New Mexico Health Scis CTRAlbuquerque, NM6$8.6 million0$0
University of Connecticut SCH of Med/dntFarmington, CT6$8.5 million0$0
University of Oregon EugeneEugene, OR6$8.5 million0$0
University of CincinnatiCincinnati, OH5$8.1 million0$0
Oregon Health & Science UniversityPortland, OR8$8 million0$0
University of DenverDenver, CO5$7.9 million0$0
University of ChicagoChicago, IL6$7.8 million0$0
Harvard Medical SchoolBoston, MA8$7.8 million0$0
Westat, Inc.Bethesda, MD2$7.7 million0$0
Oregon Research InstituteSpringfield, OR2$7.6 million0$0
Case Western Reserve UniversityCleveland, OH5$7.3 million0$0
SUNY Downstate Medical CenterBrooklyn, NY5$6.7 million0$0
Dartmouth CollegeHanover, NH4$6.5 million0$0
University of Massachusetts AmherstAmherst, MA6$6.5 million0$0
Nathan S. Kline Institute for Psych ResOrangeburg, NY7$6.5 million0$0
University of Wisconsin-MadisonMadison, WI8$6.4 million0$0
Lovelace Biomedical Research InstituteAlbuquerque, NM2$6.2 million0$0
New York Genome CenterNew York, NY3$6 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX7$5.6 million0$0
Upstate Medical UniversitySyracuse, NY5$5.5 million0$0
Medical University of South CarolinaCharleston, SC5$5.5 million0$0
University of LouisvilleLouisville, KY7$5.3 million0$0
Virginia Polytechnic Institute and State UniversityBlacksburg, VA2$5.2 million0$0
Research Inst Nationwide Children's HospColumbus, OH4$5.1 million0$0
Evidence-Based Practice Institute, Inc.Seattle, WA2$5 million0$0
University of Colorado at BoulderBoulder, CO4$5 million0$0
Rbhs-Robert Wood Johnson Medical SchoolPiscataway, NJ5$4.9 million0$0
University of Cape TownRondebosch2$4.9 million0$0
Mayo Clinic RochesterRochester, MN5$4.9 million0$0
Geisinger ClinicDanville, PA2$4.8 million0$0
Rhode Island HospitalProvidence, RI3$4.7 million0$0
New York UniversityNew York, NY6$4.6 million0$0
Boston Va Research Institute, Inc.Boston, MA2$4.5 million0$0
Drexel UniversityPhiladelphia, PA4$4.4 million0$0
University of Miami School of MedicineCoral Gables, FL3$4.2 million0$0
Pennsylvania State Univ University ParkUniversity Park, PA5$4.1 million0$0
Wayne State UniversityDetroit, MI3$4.1 million0$0
Thomas Jefferson UniversityPhiladelphia, PA4$4.1 million0$0
University of Notre DameNotre Dame, IN2$3.8 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025735$484,542,7080$0
2024843$485,899,9000$0
2023872$463,703,7660$0
2022883$461,974,9890$0
2021866$451,327,9930$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 6 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIHMay 7, 2027Not listedNotice number printed on 4 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185NIHMay 7, 2027Not listedNotice number printed on 3 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required)PA-24-193NIHMay 7, 2027Not listedNotice number printed on 1 award here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)PA-24-175NIHMay 7, 2027Not listedNotice number printed on 1 award here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 1 award here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)PA-24-184NIHMay 8, 2027Not listedNotice number printed on 1 award here
Developing novel theory and methods for understanding the genetic architecture of complex human traits (R01 Clinical Trial Not Allowed)PAR-25-255NIH93.242November 5, 2026Not listedSame assistance listing 93.242 as 1,490 awards here
Advancing Real-World Effectiveness Evidence for Rapid-Acting Psychotropic Interventional Drugs (RAPIDs)RFA-MH-27-150NIH93.242November 13, 2026Not listedSame assistance listing 93.242 as 1,490 awards here
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)PAR-25-370NIH93.242November 16, 2026$50,000Same assistance listing 93.242 as 1,490 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.242November 18, 2026Not listedSame assistance listing 93.242 as 1,490 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.242November 18, 2026Not listedSame assistance listing 93.242 as 1,490 awards here
Seamless Early-Stage Clinical Drug Development (Phase 1 to 2a) for Novel therapeutic Agents for the Spectrum of Alzheimer's Disease (AD) and AD-related Dementias (ADRD) (UG3/UH3 Clinical Trial Required)PAR-25-226NIH93.242November 19, 2026Not listedSame assistance listing 93.242 as 1,490 awards here
Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional)PA-23-317NIH93.242November 24, 2026Not listedSame assistance listing 93.242 as 1,490 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIH93.242December 3, 2026Not listedSame assistance listing 93.242 as 1,490 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIH93.242December 3, 2026Not listedSame assistance listing 93.242 as 1,490 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.242December 4, 2026Not listedSame assistance listing 93.242 as 1,490 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.242January 7, 2027$375,000Same assistance listing 93.242 as 1,490 awards here
Personal Health Informatics for Delivering Actionable Insights to Individuals (R01 Clinical Trial Optional)PAR-25-235NIH93.242January 7, 2027$250,000Same assistance listing 93.242 as 1,490 awards here
Accelerating Solutions to Improve Access and Quality of Empirically-Supported Practices for Youth Mental Health (R01 Clinical Trial Optional)PAR-25-310NIH93.242January 7, 2027Not listedSame assistance listing 93.242 as 1,490 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.