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Data / Research funding / Prescription Drug Abuse

Prescription Drug Abuse: 60 NIH awards ($27.7M) to 49 organizations

60 NIH awards ($27.7M) in the NIH spending category Prescription Drug Abuse, to 49 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

Topic
NIH spending category

Awards

60 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Opiod Analgesic Reduction Study (OARS): Managing Acute Post-Operative Surgical PainNIHNational Institute of Dental & Craniofacial Research2021$3,127,499August 1, 2020July 31, 2024FELDMAN, CECILEreporter.nih.gov
Development of an intranasal, long duration opioid antagonist to treat opioid overdoseNIHNational Institute on Drug Abuse2021$1,800,581May 1, 2018March 31, 2022CRYSTAL, ROGERreporter.nih.gov
Development of a novel analgesic for mixed inflammatory and neuropathic pain statesNIHNational Institute of Neurological Disorders and Stroke2021$1,734,409September 15, 2021August 31, 2023GHETTI, ANDREAreporter.nih.gov
Non-Opioid Post-Operative Pain Management Using Bupivacaine-loaded Poly(ester urea) MeshNIHNational Institute of General Medical Sciences2021$1,730,751September 13, 2021August 31, 2023YU, JIAYIreporter.nih.gov
Application of Economics & Social psychology to improve Opioid Prescribing Safety (AESOPS) TrialNIHNational Institute on Aging2021$1,225,740September 15, 2017August 31, 2023DOCTOR, JASON N.reporter.nih.gov
BioMote for Opioid Use Disorder (OUD) RecoveryNIHNational Institute on Drug Abuse2021$1,193,511August 1, 2017May 31, 2023SCHMIDLE, PATRIKreporter.nih.gov
Clinical and Genetic Study of Prescription Opioid AddictionNIHNational Institute on Drug Abuse2021$737,349September 1, 2017May 31, 2024TROIANI, VANESSAreporter.nih.gov
NON-DEPENDENT OPIOID MISUSERS AS GWAS CONTROLSNIHNational Institute on Drug Abuse2021$648,323September 1, 2017May 31, 2023NELSON, ELLIOT Creporter.nih.gov
Evaluation of Marijuana and Opioid Drug Interactions: Assessment of the Safety Profile, Abuse-Related Pharmacodynamic Effects and Models of Drug IntakeNIHNational Institute on Drug Abuse2021$609,253August 1, 2018May 31, 2025BABALONIS, SHANNAreporter.nih.gov
Adapting the HOPE Online Support Intervention to Increase MAT Uptake Among OUD PatientsNIHNational Center for Complementary & Integrative Health2021$588,750September 28, 2019August 31, 2024YOUNG, SEANreporter.nih.gov
Intervention to Increase Naloxone Engagement and Distribution in Community Pharmacies: A Four-State Randomized TrialNIHNational Institute on Drug Abuse2021$587,534May 1, 2020October 31, 2023GREEN, TRACI Creporter.nih.gov
Reducing ethnic and language disparities in Spanish-speaking patients who receive opioids for postsurgical painNIHNational Institute on Drug Abuse2021$581,748September 30, 2020August 31, 2023URMAN, RICHARD D.reporter.nih.gov
Bivalent Ligands as Chemical Probes to Study Opioid Abuse-enhanced HIV InfectionNIHNational Institute on Drug Abuse2021$567,877July 1, 2017May 31, 2023ZHANG, YANreporter.nih.gov
oPIOIDS: Prevention of Iatrogenic Opioid Dependence after SurgeryNIHNational Institute on Drug Abuse2021$561,528July 1, 2017April 30, 2023WALJEE, JENNIFER FILIPreporter.nih.gov
Reducing Non-Medical Opioid Use: An automatically adaptive mHealth InterventionNIHNational Institute on Drug Abuse2021$552,775May 1, 2016January 31, 2023BOHNERT, AMY S Breporter.nih.gov
Probing mechanisms of amphetamine action at plasma membrane and vesicular transporters in vitro and in vivoNIHNational Institute on Drug Abuse2021$539,654April 1, 2017January 31, 2023JAVITCH, JONATHAN Areporter.nih.gov
Multi-organ-on-chip device for modeling opioid reinforcement and withdrawal, and the negative affective component of pain: a therapeutic screening tool.NIHNational Center for Advancing Translational Sciences2021$531,057September 26, 2019July 31, 2022MAIDMENT, NIGEL Treporter.nih.gov
Examining the Consequences of Reductions in Opioid Prescribing on Patients, Clinical Care, and Community HealthNIHNational Institute on Drug Abuse2021$514,868May 1, 2017February 29, 2024KNIGHT, KELLY RAYreporter.nih.gov
OPTIMIZING OUTPATIENT ANESTHESIA: IMPROVING ANALGESIA AND REDUCING OPIOID MISADVENTURENIHNational Institute on Drug Abuse2021$505,171July 1, 2018December 31, 2023KHARASCH, EVAN D.reporter.nih.gov
EpiCenter ? EPIdemiology of opioid prescribing in community health CENTERsNIHNational Institute on Drug Abuse2021$490,523August 1, 2018April 30, 2022MUENCH, JOHNreporter.nih.gov
Pharmacological and behavioral effects of MCAM: a long-acting, μ opioid receptor antagonist for treatment of opioid overdose and opioid abuse disorderNIHNational Institute on Drug Abuse2021$461,788May 15, 2019January 31, 2023CLARKE, WILLIAM Preporter.nih.gov
Novel opioids that protect against oral overdose and disrupt the progression to misuse, abuse, and addictionNIHNational Institute on Drug Abuse2021$452,530June 15, 2018December 31, 2022JENKINS, THOMAS Ereporter.nih.gov
Neurobiological mechanisms of prescription opioid withdrawalNIHNational Institute on Drug Abuse2021$447,386September 15, 2017December 31, 2022CHARTOFF, ELENA Hreporter.nih.gov
Real-time Predictors of Prescription Drug Misuse by College Students and Assessment of Misuse on Their Developmental TrajectoriesNIHNational Institute on Drug Abuse2021$394,779May 16, 2021February 28, 2023PAPP, LAUREN Mreporter.nih.gov
Opioid Treatment and Recovery through a Safe Pain Management ProgramNIHNational Institute on Drug Abuse2021$378,392September 30, 2018June 30, 2023PRICE-HAYWOOD, EBONI Greporter.nih.gov
Role of SK2 channels in morphine dependenceNIHNational Institute on Drug Abuse2021$374,464May 1, 2017January 31, 2023MORON-CONCEPCION, JOSE Areporter.nih.gov
A High School Program for Preventing Prescription Drug AbuseNIHNational Institute on Drug Abuse2021$371,950May 1, 2017July 31, 2023WILLIAMS, CHRISTOPHERreporter.nih.gov
The role of the VTA-lateral habenula circuit in opioid mediated behaviorsNIHNational Institute on Drug Abuse2021$356,625September 1, 2017June 30, 2023MARGOLIS, ELYSSAreporter.nih.gov
Alternatives to prescription opioids: a precision medicine approach to harnessing endogenous opioids for pain relief and circumvention of prescription opioid abuseNIHNational Institute on Drug Abuse2021$351,379August 1, 2017May 31, 2024STEWART, MARK Greporter.nih.gov
Identification of cells and signaling mechanisms underlying opioid analgesia and side effectsNIHNational Institute on Drug Abuse2021$349,875June 1, 2020May 31, 2023SCHERRER, GREGORYreporter.nih.gov
Mining Social Media Big Data for Toxicovigilance: Automating the Monitoring of Prescription Medication Abuse via Natural Language Processing and Machine Learning MethodsNIHNational Institute on Drug Abuse2021$332,121September 1, 2019May 31, 2023SARKER, ABEED Hreporter.nih.gov
The Microbiome in opioid use and abuseNIHNational Institute on Drug Abuse2021$280,577June 1, 2020May 31, 2023WHISTLER, JENNIFER Lreporter.nih.gov
Targeting Leptin Pathway to Treat Opioid-Induced Respiratory DepressionNIHNational Institute on Drug Abuse2021$259,438November 15, 2020October 31, 2022POLOTSKY, VSEVOLOD Yreporter.nih.gov
MyTPill: A Novel Strategy to Monitor Antiretroviral Adherence among HIV+ Prescription Opioid UsersNIHNational Institute on Drug Abuse2021$252,947June 1, 2019August 31, 2021BOYER, EDWARD Wreporter.nih.gov
Molecular basis for ligand and cell type specific regulation of opioid receptorsNIHNational Institute on Drug Abuse2021$249,000September 1, 2019August 31, 2023LOBINGIER, BRADENreporter.nih.gov
Characterization GPR83 and identification of small molecule ligands targeting this receptor for the treatment of substance use disorders.NIHNational Institute on Drug Abuse2021$247,028December 1, 2020November 30, 2021DEVI, LAKSHMI Areporter.nih.gov
Real Time Monitoring of Prescription Opioid and Cannabis Co-Use in Patients with Chronic PainNIHNational Institute on Drug Abuse2021$245,625March 15, 2020February 28, 2023THRUL, JOHANNESreporter.nih.gov
In vivo characterization of opioid biased agonistsNIHNational Institute on Drug Abuse2021$245,568January 1, 2019November 30, 2022PARONIS, CAROL Areporter.nih.gov
Connectomics of relapse to aggression seekingNIHNational Institute on Drug Abuse2021$241,782August 1, 2019July 31, 2022GOLDEN, SAMreporter.nih.gov
Opioid Support and Risk Reduction Online PlatformNIHNational Institute on Drug Abuse2021$238,994January 1, 2021December 31, 2022GARETT, RENEEreporter.nih.gov
Impact of prenatal opioid exposure on long-range brain circuit connectivity and behaviorNIHNational Institute on Drug Abuse2021$231,250July 1, 2020April 1, 2022MILLER, COURTNEY Areporter.nih.gov
Exploring steroid-based therapies to reduce opioid abuseNIHNational Institute on Drug Abuse2021$190,625April 15, 2020March 31, 2023BORTOLATO, MARCOreporter.nih.gov
iTransform: Wearable Biosensors to Detect the Evolution of Opioid Tolerance in Opioid Naïve IndividualsNIHNational Institute on Drug Abuse2021$188,616April 1, 2019March 31, 2023CARREIRO, STEPHANIE Preporter.nih.gov
Pilot Implementation of Measurement-Based Care in Community Opioid Treatment ProgramsNIHNational Institute on Drug Abuse2021$186,362April 1, 2021February 28, 2026SCOTT, KELLIreporter.nih.gov
A Behavioral Intervention to Engage Emerging Adults in Addiction Treatment after a Non-fatal Opioid OverdoseNIHNational Institute on Drug Abuse2021$180,122July 15, 2017June 30, 2023BAGLEY, SARAH Mreporter.nih.gov
Understanding the Impact of Opioid Policies on the Opioid Epidemic Using Graphical Causal Models and Causal DiscoveryNIHNational Institute on Drug Abuse2021$180,021June 15, 2020January 1, 2022JALAL, HAWREreporter.nih.gov
Adaptive Treatment Models for the Management of Drug Use DisordersNIHNational Institute on Drug Abuse2021$177,902September 1, 2010April 30, 2024MCKAY, JAMES R.reporter.nih.gov
Circuit-specific molecular mechanisms in fentanyl use and relapseNIHNational Institute on Drug Abuse2021$175,792April 1, 2020September 30, 2021FOX, MEGAN ELIZABETHreporter.nih.gov
Discovery of novel pharmacotherapeutic targets for opioid addictionNIHNational Institute on Drug Abuse2021$171,504August 1, 2020November 30, 2021SMITH, ALEXANDER WANLESSreporter.nih.gov
Developing a public health measure of built environment to assess risk of nonmedical opioid use and related mortality in urban and non-urban areas in New JerseyNIHNational Institute on Drug Abuse2021$167,983April 15, 2020March 31, 2023TEMPALSKI, BARBARAreporter.nih.gov
Nonmedical prescription drug misuse among US older adults: subtypes,motives, and diversion sourcesNIHNational Institute on Drug Abuse2021$135,875August 15, 2017February 28, 2022SCHEPIS, TY STEPHENreporter.nih.gov
Metabotropic glutamate regulation of synaptic rewiring in opioid addictionNIHNational Institute on Drug Abuse2021$77,142April 1, 2019March 31, 2022ZUCCA, STEFANOreporter.nih.gov
Developing a Novel Mixed Opioid Agonist for the Treatment of OUDNIHNational Institute on Drug Abuse2021$55,000May 24, 2021March 31, 2022VERSI, EBRAHIMreporter.nih.gov
Development of the Strength Band Platform, a Technology Assisted Therapy Platform to Aid with Opioid Abuse Treatment.NIHNational Institute on Drug Abuse2021$55,000September 15, 2020June 30, 2022REESER, DAVIDreporter.nih.gov
Pre-clinical assessments of dose-sparing and anti-addictive adjuvants to prevent the future abuse of opioid analgesicsNIHNational Institute on Drug Abuse2021$53,965September 30, 2020January 19, 2023WHITE, ALLISONreporter.nih.gov
Opioid-induced changes to cannabinergic regulation of dopamine and motivation during protracted withdrawalNIHNational Institute of Neurological Disorders and Stroke2021$31,156July 1, 2021June 30, 2022GOMEZ, DEVAN MARCreporter.nih.gov
Identifying mechanisms and biomarkers predictive of individual variability in efficacy of vaccines against opioid use disorderNIHNational Institute on Drug Abuse2021$26,961November 1, 2021August 19, 2022CROUSE, BETHANY Kreporter.nih.gov
Distress Tolerance and Benzodiazepine Discontinuation in Opioid Agonist TherapyNIHNational Institute on Drug Abuse2021$15,459August 15, 2017September 11, 2021PARK, TAE WOOreporter.nih.gov
Therapeutic selectivity of biased mu-opioid agonists.NIHNational Institute on Drug Abuse2021$13,490April 2, 2019June 30, 2021ZAMARRIPA, CARLOS AUSTINreporter.nih.gov
Collaborative Care Office-Based Opioid Treatment for Adolescents and Young AdultsNIHNational Institute on Drug Abuse2021$564July 1, 2018July 14, 2021HADLAND, SCOTT EVANreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Rbhs-School of Dental MedicineNewark, NJ1$3.1 million0$0
Opiant Pharmaceuticals, Inc.Santa Monica, CA1$1.8 million0$0
Anabios CorporationSan Diego, CA1$1.7 million0$0
21medtech LLCDurham, NC1$1.7 million0$0
University of Southern CaliforniaLos Angeles, CA1$1.2 million0$0
Cari Health, Inc.San Diego, CA1$1.2 million0$0
University of Michigan at Ann ArborAnn Arbor, MI2$1.1 million0$0
Washington UniversitySaint Louis, MO2$1 million0$0
University of California, San FranciscoSan Francisco, CA2$871,4930$0
Brigham and Women's HospitalBoston, MA2$834,6950$0
Oregon Health & Science UniversityPortland, OR2$739,5230$0
Geisinger ClinicDanville, PA1$737,3490$0
Mclean HospitalBelmont, MA2$692,9540$0
University of KentuckyLexington, KY1$609,2530$0
University of California-IrvineIrvine, CA1$588,7500$0
Brandeis UniversityWaltham, MA1$587,5340$0
Virginia Commonwealth UniversityRichmond, VA1$567,8770$0
Columbia University Health SciencesNew York, NY1$539,6540$0
University of California Los AngelesLos Angeles, CA1$531,0570$0
Duke UniversityDurham, NC1$505,1710$0
Johns Hopkins UniversityBaltimore, MD2$505,0630$0
University of Texas HLTH Science CenterSan Antonio, TX1$461,7880$0
Elysium Therapeutics, Inc.Lyons, CO1$452,5300$0
Icahn School of Medicine at Mount SinaiNew York, NY2$418,5320$0
University of Wisconsin-MadisonMadison, WI1$394,7790$0
Ochsner Clinic FoundationNew Orleans, LA1$378,3920$0
National Health Promotion AssociatesWhite Plains, NY1$371,9500$0
SUNY Downstate Medical CenterBrooklyn, NY1$351,3790$0
Univ of North Carolina Chapel HillChapel Hill, NC1$349,8750$0
Emory UniversityAtlanta, GA1$332,1210$0
Scripps FloridaJupiter, FL2$308,3920$0
University of California at DavisDavis, CA1$280,5770$0
University of WashingtonSeattle, WA1$241,7820$0
ElevateuLos Angeles, CA1$238,9940$0
Boston Medical CenterBoston, MA3$196,1450$0
University of UtahSalt Lake City, UT1$190,6250$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA1$188,6160$0
Brown UniversityProvidence, RI1$186,3620$0
University of Pittsburgh at PittsburghPittsburgh, PA1$180,0210$0
University of PennsylvaniaPhiladelphia, PA1$177,9020$0
University of Maryland BaltimoreBaltimore, MD1$175,7920$0
Ndri-Usa, Inc.New York, NY1$167,9830$0
Texas State University - San MarcosSan Marcos, TX1$135,8750$0
DMK Pharmaceuticals, Inc.Somerville, NJ1$55,0000$0
Opiaid, Inc.Wilmington, NC1$55,0000$0
West Virginia University Research CorporationMorgantown, WV1$53,9650$0
Marquette UniversityMilwaukee, WI1$31,1560$0
University of MinnesotaMinneapolis, MN1$26,9610$0
University of Mississippi Med CTRJackson, MS1$13,4900$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
202160$27,675,9380$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
NIDA Mentored Clinical Scientist Development Program Award in Substance Use and Substance Use Disorder Research (K12 Clinical Trial Optional)PAR-24-089NIH93.279November 13, 2026$750,000Same assistance listing 93.279 as 53 awards here
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)PAR-25-370NIH93.279November 16, 2026$50,000Same assistance listing 93.279 as 53 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.279November 18, 2026Not listedSame assistance listing 93.279 as 53 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.279November 18, 2026Not listedSame assistance listing 93.279 as 53 awards here
Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional)PA-23-317NIH93.279November 24, 2026Not listedSame assistance listing 93.279 as 53 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIH93.279December 3, 2026Not listedSame assistance listing 93.279 as 53 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIH93.279December 3, 2026Not listedSame assistance listing 93.279 as 53 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.279December 4, 2026Not listedSame assistance listing 93.279 as 53 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)PAR-27-039NIH93.279January 5, 2027Not listedSame assistance listing 93.279 as 53 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)PAR-27-040NIH93.279January 5, 2027Not listedSame assistance listing 93.279 as 53 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.279January 7, 2027$375,000Same assistance listing 93.279 as 53 awards here
Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)PAR-25-378NIH93.279January 7, 2027Not listedSame assistance listing 93.279 as 53 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.279January 7, 2027Not listedSame assistance listing 93.279 as 53 awards here
HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)RFA-DA-28-011NIH93.279January 26, 2027Not listedSame assistance listing 93.279 as 53 awards here
HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) - Building Engagement, Assistance, Capacity, Outreach, and Networks (BEACON) Center (U2C Clinical Trial Not Allowed)RFA-DA-28-012NIH93.279January 26, 2027Not listedSame assistance listing 93.279 as 53 awards here
Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)PAR-24-268NIH93.279January 27, 2027$500,000Same assistance listing 93.279 as 53 awards here
BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)RFA-NS-24-031NIH93.279January 28, 2027$750,000Same assistance listing 93.279 as 53 awards here
Neural Ensembles & Used Substances (NExUS) Collaboratory: Building a Multimodal Inventory of Cell Ensembles Encoding the Effects of Addictive Substances (U01 Clinical Trial Not Allowed)RFA-DA-28-013NIH93.279February 8, 2027Not listedSame assistance listing 93.279 as 53 awards here
BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)RFA-MH-26-170NIH93.279February 8, 2027Not listedSame assistance listing 93.279 as 53 awards here
NIDA Animal Genomics Program (U01 Clinical Trial Not Allowed)PAR-24-269NIH93.279February 11, 2027Not listedSame assistance listing 93.279 as 53 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.