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Data / Research funding / Osteoporosis

Osteoporosis: 514 NIH awards ($663M) to 163 organizations

514 NIH awards ($663M) in the NIH spending category Osteoporosis, to 163 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Awards

The 500 largest of 514 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
FSH - an Aging Hormone?NIHNational Institute on Aging2021 to 2025$15,166,862February 1, 2019April 30, 2029ZAIDI, MONEreporter.nih.gov
Prevention of Fractures in Patients with Parkinson's DiseaseNIHNational Institute on Aging2022 to 2024$13,269,734September 30, 2018February 28, 2026CUMMINGS, STEVEN RONreporter.nih.gov
Trans-omics Integration of Multi-omics Studies for OsteoporosisNIHNational Institute on Aging2021 to 2025$12,202,183September 15, 2017June 30, 2027DENG, HONG-WENreporter.nih.gov
Long term fracture risk and change in peripheral bone in the oldest old men: The MrOS studyNIHNational Institute on Aging2021 to 2024$12,122,513September 30, 2020May 31, 2026CAWTHON, PEGGY MANNENreporter.nih.gov
Beta1-selective blockade for prevention of postmenopausal bone loss: A randomized controlled trialNIHNational Institute on Aging2021 to 2025$12,029,156January 1, 2021December 31, 2026KHOSLA, SUNDEEPreporter.nih.gov
Center for Musculoskeletal Disease Research (CMDR)NIHNational Institute of General Medical Sciences2021 to 2025$11,683,826February 16, 2018January 31, 2028O'BRIEN, CHARLES Areporter.nih.gov
Kynurenine accumulation drives loss of muscle and bone function with agingNIHNational Institute on Aging2021 to 2025$11,563,609May 1, 2011May 31, 2027ISALES, CARLOS M.reporter.nih.gov
Phase II COBRE in Mesenchymal and Neural Regulation of Metabolic NetworksNIHNational Institute of General Medical Sciences2021 to 2025$10,635,678September 1, 2017August 31, 2028LIAW, LUCYreporter.nih.gov
The Aging Pituitary/Gonadal AxisNIHNational Institute on Aging2021 to 2025$8,508,061April 15, 2009May 31, 2028BOUSFIELD, GEORGE Rreporter.nih.gov
A Humanized Monoclonal FSH Blocking Antibody for Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$8,293,749September 30, 2021August 31, 2026ZAIDI, MONEreporter.nih.gov
Center of Biomedical Research Excellence in Matrix Biology Phase IINIHNational Institute of General Medical Sciences2021 to 2023$8,248,947August 1, 2014May 31, 2025OXFORD, JULIA THOMreporter.nih.gov
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC): TASK AREA A AND A2NIHNational Heart, Lung, and Blood Institute2021 to 2025$6,882,445September 29, 2025September 28, 2026WACTAWSKI-WENDE, JEANreporter.nih.gov
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC): TASK AREA A AND A2NIHNational Heart, Lung, and Blood Institute2021 to 2025$6,534,889September 29, 2025September 28, 2026STEFANICK, MARCIAreporter.nih.gov
Exercise and Bisphosphonate Use to Minimize Weight Loss Associated Bone Loss among Older AdultsNIHNational Institute on Aging2022 to 2025$5,597,882September 1, 2022August 31, 2027BEAVERS, KRISTEN MARIEreporter.nih.gov
Adapting MultiPLe behavior Interventions that eFfectively Improve (AMPLIFI) Cancer Survivor HealthNIHNational Cancer Institute2021 to 2023$5,295,451September 1, 2018August 31, 2025DEMARK-WAHNEFRIED, WENDYreporter.nih.gov
Measuring Whole and Tissue Level Bone Strength in menNIHNational Institute on Aging2021 to 2025$5,213,084January 1, 2021May 31, 2027BURKS, PETERreporter.nih.gov
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC): TASK AREA A AND A2NIHNational Heart, Lung, and Blood Institute2021 to 2025$5,000,825September 29, 2025September 28, 2026JACKSON, REBECCAreporter.nih.gov
Calculator for Length of Use of Bisphosphonates (CLUB)NIHNational Institute on Aging2022 to 2025$4,867,837September 15, 2022June 30, 2027CARBONE, LAURA Dreporter.nih.gov
HIV and musculoskeletal frailty: implications for care, policy and researchNIHNational Institute of Nursing Research2022 to 2025$4,358,664August 18, 2022May 31, 2027LOSINA, ELENAreporter.nih.gov
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC): TASK AREA A AND A2NIHNational Heart, Lung, and Blood Institute2021 to 2025$4,249,024September 29, 2025September 28, 2026VITOLINS, MARAreporter.nih.gov
Pooling International Cohort Studies of Long-Term Bisphosphonate Use and Atypical Femur FracturesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$4,209,170September 19, 2022August 31, 2027BAUER, DOUGLAS Creporter.nih.gov
Biomarker-Based Phase IIB Trial of (Bazedoxifene-Conjugated Estrogen) to Reduce Risk for Breast CancerNIHNational Cancer Institute2021 to 2025$4,143,666February 26, 2021July 31, 2027FABIAN, CAROL J.reporter.nih.gov
NIH Osteoporosis and Related Bone Diseases~National Resource Center (NRC)NIHNational Heart, Lung, and Blood Institute2021 to 2022$4,052,641January 15, 2018January 14, 2023BOWEN, MATTreporter.nih.gov
Development of Cortical Bone Mechanics Technology for Enhancing the Diagnosis of OsteoporosisNIHNational Institute on Aging2021 to 2024$4,035,885December 1, 2017June 30, 2025DICK, ANDREWreporter.nih.gov
Core Center for Musculoskeletal Biology and MedicineNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$4,002,359July 15, 2019April 30, 2029HSIAO, EDWARD Creporter.nih.gov
Systemic regulation of metastasisNIHNational Cancer Institute2021 to 2024$3,947,638September 18, 2018August 31, 2025LYDEN, DAVID CHARLESreporter.nih.gov
Proof-of-Concept and Mechanistic Studies to Repurpose Erectile Dysfunction Drugs for Elderly FemalesNIHNational Institute on Aging2021 to 2025$3,872,647May 1, 2021February 28, 2026YUEN, TONYreporter.nih.gov
Urine cadmium and risk of fracture and bone lossNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,838,627September 20, 2021August 31, 2027MELIKER, JAYMIE Rreporter.nih.gov
PPARG regulates osteocyte bioenergetics and function during agingNIHNational Institute on Aging2021 to 2025$3,381,593September 30, 2021May 31, 2027LECKA-CZERNIK, BEATA ANNAreporter.nih.gov
Identification of Novel Genes Impacting Osteoblast ActivityNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,308,234July 12, 2021June 30, 2027ACKERT-BICKNELL, CHERYL LYNNEreporter.nih.gov
Predictors of Antiretroviral Immunereconstitution Bone Loss - the Gut and the MicrobiomeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,266,890September 21, 2021August 31, 2026WEITZMANN, MERVYN NEALEreporter.nih.gov
Small Molecule Signaling in Caenorhabditis elegansNIHNational Institute of General Medical Sciences2021 to 2025$3,212,993May 1, 2019January 31, 2029SCHROEDER, FRANK CLEMENSreporter.nih.gov
Novel Molecular Biomarkers of Bone MicroarchitectureNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,202,138September 30, 1991March 31, 2027KIEL, DOUGLAS P.reporter.nih.gov
Targeting a novel inter-tissue L-BAIBA/FGF23 axis to enhance adaptive musculoskeletal remodeling in agingNIHNational Institute on Aging2025$3,126,515August 15, 2025May 31, 2029WHITE, KENNETH Ereporter.nih.gov
Vascular Mechanisms Underlying Skeletal Fragility in Older AdultsNIHNational Institute on Aging2021 to 2025$3,114,001December 15, 2020November 30, 2026SAMELSON, ELIZABETH Jreporter.nih.gov
Acid-Base Status as a Novel Risk Factor for FracturesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$3,080,006June 1, 2019February 28, 2026PAIK, JULIEreporter.nih.gov
Intensive Lifestyle Intervention, Metabolomics, and Risk of Frailty Fracture in Overweight or Obese Patients with Type 2 DiabetesNIHNational Institute on Aging2021 to 2025$3,069,231September 30, 2021May 31, 2027ZHAO, QIreporter.nih.gov
Effects of Sleep on Bone Density and Strength in Adolescence: A Prospective Longitudinal StudyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,808,161March 1, 2020January 31, 2027MITCHELL, JONATHAN ANDREWreporter.nih.gov
Serotonin and Skeletal HealthNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,794,021August 1, 2022July 31, 2027WALKER, MARCELLA DONOVANreporter.nih.gov
Skeletal Health Outcomes among US Asian WomenNIHNational Institute on Aging2021 to 2025$2,781,738September 15, 2021June 30, 2027LO, JOAN Creporter.nih.gov
Understanding the skeleton in Down SyndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,772,646June 1, 2024May 31, 2027SUVA, LARRY J.reporter.nih.gov
Systems Genetics of Bone RegenerationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,717,663April 15, 2022January 31, 2027FARBER, CHARLES Rreporter.nih.gov
Wearable Vibration Device to Prevent Bone Loss in Postmenopausal WomenNIHNational Institute on Aging2021 to 2022$2,710,602June 15, 2014December 31, 2023HILLSTROM, DEREKreporter.nih.gov
The Role of Erythroferrone in Regulating Bone Metabolism in Beta-ThalassemiaNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,707,032September 1, 2015January 31, 2026GINZBURG, YELENAreporter.nih.gov
Studies of the fate of the osteoclastNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,655,069June 1, 1995December 31, 2026BOYCE, BRENDAN Freporter.nih.gov
Genomics of bone and body composition traits in childrenNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,651,635August 7, 2020June 30, 2026ZEMEL, BABETTE Sreporter.nih.gov
Discovery of osteoblast and osteoclast bone mass effector genes using advanced genomicsNIHNational Institute on Aging2022 to 2025$2,627,548August 3, 2022April 30, 2027HANKENSON, KURT DAVIDreporter.nih.gov
Gastric Endocrine Functions in Skeletal HomeostasisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$2,608,068September 1, 2025August 31, 2029LI, ZIRUreporter.nih.gov
Novel precision medicine approach to treatment of osteoporosis based on bone turnoverNIHNational Institute on Aging2021 to 2025$2,584,593September 30, 2021August 31, 2026RAO, MADHUMATHIreporter.nih.gov
Systemic Bone Loss Following Fracture in HumansNIHNational Institute on Aging2023 to 2025$2,557,825September 30, 2023May 31, 2028KAZAKIA, GALATEIA Jreporter.nih.gov
Roles of Noncoding RNA in Bone RegenerationNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,547,514March 1, 2016August 31, 2025CHEN, JAKE JINKUNreporter.nih.gov
Examining the Skeletal Effects of PsychostimulantsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,545,386August 20, 2020June 30, 2026CALARGE, CHADI A.reporter.nih.gov
Benefits and Harms of Long-term Osteoporosis Pharmacotherapy: Impact of Treatment Length, Type, Switching, and HolidaysNIHNational Institute on Aging2022 to 2025$2,525,120September 15, 2022June 30, 2027HAYES, KALEEN NICOLEreporter.nih.gov
Hip Fracture Pathology in Chronic Kidney DiseaseNIHNational Institute on Aging2021 to 2024$2,515,797March 1, 2020December 31, 2025HUGHES-AUSTIN, JAN MARIEreporter.nih.gov
High-dose Vitamin D Supplementation for ADT-Induced Bone Loss in Older Prostate Cancer PatientsNIHNational Cancer Institute2022 to 2025$2,508,029December 17, 2021November 30, 2026PEPPONE, LUKE JOSEPHreporter.nih.gov
Role of the gut microbiome in the bone loss induced by hyperparathyroidism in mice and humansNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,440,273February 1, 2021January 31, 2026PACIFICI, ROBERTOreporter.nih.gov
Comparative Effectiveness and Safety of Osteoporosis Drug TherapiesNIHNational Institute on Aging2022 to 2025$2,418,555September 15, 2022June 30, 2027BRITO CAMPANA, JUAN Preporter.nih.gov
Skeletal Health and Bone Marrow Composition Among YouthNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,405,377April 6, 2020March 19, 2025DIVASTA, AMY Dreporter.nih.gov
Role for prelamin A in premature and physiological agingNIHNational Institute on Aging2022 to 2025$2,386,276August 1, 2022April 30, 2027MICHAELIS, SUSAN D.reporter.nih.gov
Epithelial Osteoblast Function: The Role of Acid TransportNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,377,265May 1, 2020January 31, 2026BLAIR, HARRY COLBERTreporter.nih.gov
Ultrashort Echo Time (UTE) Magnetic Resonance Imaging of BoneNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,376,673September 17, 2015February 28, 2026DU, JIANGreporter.nih.gov
Identifying A Skeleton-Derived Factor for Vascular AgingNIHNational Institute on Aging2021 to 2025$2,368,758April 1, 2021December 31, 2026WAN, MEIreporter.nih.gov
Causal Genes at BMD LociNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,360,342May 15, 2020April 30, 2027KWON, RONALD Yreporter.nih.gov
PKG Regulation of Sirtuin 1 as a Novel Treatment Strategy for Age-related OsteoporosisNIHNational Institute on Aging2021 to 2025$2,324,065September 5, 2021May 31, 2027PILZ, RENATE Breporter.nih.gov
Control of bone physiology by a novel type of adipose cellsNIHNational Institute on Aging2021 to 2025$2,313,640May 15, 2021February 28, 2027QIN, LINGreporter.nih.gov
Structure and function of PTH class B GPCRNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,299,273April 1, 2018March 31, 2027VILARDAGA, JEAN-PIERREreporter.nih.gov
Computed tomography muscle size and composition associations with hip and spine bone strength over 4 years: SOMMA-CTNIHNational Institute on Aging2023 to 2025$2,284,397September 5, 2023May 31, 2028WEAVER, ASHLEYreporter.nih.gov
A Novel Bone Targeted Antibiotic Therapy for the Treatment of Infected FracturesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,268,141April 22, 2024March 31, 2027EBETINO, FRANK H.reporter.nih.gov
A dual-layer flat panel x-ray detector based on an engineered amorphous chalcogenide alloy for quantifying coronary artery calciumNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$2,262,800September 7, 2022May 31, 2027ABBASZADEH, SHIVAreporter.nih.gov
A lifecourse approach to women's cardiometabolic and bone health: from fertility to perimenopauseNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$2,230,852July 10, 2019April 30, 2025OKEN, EMILYreporter.nih.gov
Leveraging modeling-based bone formation for osteoporosis treatmentNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,226,630March 5, 2021January 31, 2027LIU, XIAOWEI SHERRYreporter.nih.gov
TASK ORDER FOR TWO NATIONAL INFORMATION CLEARNINGHOUSESNIHNational Heart, Lung, and Blood Institute2023 to 2024$2,222,528January 15, 2023June 14, 2024ROBINSON, NATEreporter.nih.gov
Innovative Approach to Geriatric OsteoporosisNIHNational Institute on Aging2021 to 2024$2,220,663June 1, 2020March 31, 2026GREENSPAN, SUSAN Lreporter.nih.gov
Roles of Collagen and Water in the Fracture Resistance of BoneNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,220,473September 1, 2012May 31, 2027NYMAN, JEFFRY STEPHENreporter.nih.gov
Mechanism of action of PTH: New signaling components that regulate bone formation and bone marrow fatNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,199,383May 5, 2020March 31, 2026BARON, ROLAND Ereporter.nih.gov
Informing Osteoporosis GWAS Using NetworksNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,176,376July 15, 2020April 30, 2027FARBER, CHARLES Rreporter.nih.gov
Role of FGF23 in Bone, Kidney, Blood, Crosstalk in Sickle Cell Disease MiceNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,133,643April 1, 2022January 31, 2027HURLEY, MARJA MARIEreporter.nih.gov
Role of IL-32 as a predictor and mediator of Premature Aging Phenotypes(PAP) in HIV infection.NIHNational Institute on Aging2022 to 2025$2,130,370September 30, 2016April 30, 2027TREMBLAY, CECILEreporter.nih.gov
AAV-mediated Interrogation of the Brain FSH ReceptorNIHNational Institute on Aging2025$2,129,396August 1, 2025July 31, 2027YUEN, TONYreporter.nih.gov
Hormone Therapy for Peri- and Postmenopausal Women with HIV (HoT)NIHNational Institute on Aging2023 to 2025$2,125,280September 1, 2023August 31, 2028YIN, MICHAEL Treporter.nih.gov
The role of salt inducible kinases in parathyroid hormone action in boneNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,112,908September 15, 2018April 30, 2027WEIN, MARC NATHANreporter.nih.gov
Novel approaches to promote healing of bone loss in inflammatory arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,084,763March 14, 2022February 28, 2027SHIM, JAE-HYUCKreporter.nih.gov
Sleep, Falls and Fractures in men and women: Role of nocturnal hypoxiaNIHNational Institute on Aging2021 to 2025$2,076,018September 15, 2021May 31, 2027CAULEY, JANE ANNreporter.nih.gov
Novel Strategies for Understanding and Treating Fibrous DysplasiaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$2,059,414July 1, 2023April 30, 2028HSIAO, EDWARD Creporter.nih.gov
Chemical approaches to interrogate neuropeptide and peptide hormone signaling in diseaseNIHNational Institute of General Medical Sciences2021 to 2025$2,053,927August 1, 2021May 31, 2026CHECCO, JAMES WILLIAMreporter.nih.gov
Improved Treatment Options for Vertebral Compression Fractures in Elderly Patients Using Minimally Invasive, Image-Guided Delivery of a Regenerative Bone AdhesiveNIHNational Institute on Aging2025$2,040,626September 30, 2025June 30, 2027MCDONOUGH, BRITTANYreporter.nih.gov
Common Inflammation Pathways between Aging and Hypertension That Weaken BoneNIHNational Institute on Aging2022 to 2025$2,034,707May 15, 2022January 31, 2027HARRISON, DAVID Greporter.nih.gov
Skeletal Health in Type 1 Diabetes and the Role of Diabetic Kidney DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$2,026,915September 10, 2020July 31, 2025SCHAFER, ANNE LOUISEreporter.nih.gov
Software Platform for Automatic, Opportunistic Screening of Vertebral Compression FracturesNIHNational Institute on Aging2023 to 2025$2,022,000September 1, 2024August 31, 2026VAZIRI, ASHKANreporter.nih.gov
Serum PFAS and risk of fracture and bone lossNIHNational Institute on Aging2024 to 2025$2,019,367August 1, 2024April 30, 2029REEVES, KATHERINE WHITNEYreporter.nih.gov
Intra-articular corticosteroid injections for symptomatic osteoarthritis: The effects of injection dose, frequency, and timing on safetyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$2,017,972September 10, 2025August 31, 2028BUTLER, ANNE MOBLEYreporter.nih.gov
Response of the Osteoporotic Skeleton to Mechanical LoadingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,011,907July 13, 2001March 31, 2028SILVA, MATTHEW Jreporter.nih.gov
Preserving Geriatric Muscle with an Osteoporosis MedicationNIHNational Institute on Aging2023 to 2025$1,998,793June 1, 2023May 31, 2028KISTLER, CHRISTINE Ereporter.nih.gov
Improved Treatment of Distal Radius Fractures Using an Image-Guided, Percutaneous Delivery of a Novel Bone AdhesiveNIHNational Institute on Aging2021 to 2022$1,992,936April 1, 2018March 31, 2024HESS, BRIANreporter.nih.gov
Genomic, transcriptomic, and metabolic effects on skeletal health in Mexican AmericansNIHNational Institute on Aging2023 to 2025$1,988,234April 15, 2023January 31, 2028LEE, MIRYOUNGreporter.nih.gov
Role of disrupted polyamine synthesis during CKD-MBD related bone lossNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$1,983,733December 15, 2021November 30, 2026CLINKENBEARD, ERICA Lreporter.nih.gov
A novel cell-autonomous role for β-adrenergic receptor signaling in osteoclastsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,980,632June 1, 2021May 31, 2027MOTYL, KATHERINE JEANreporter.nih.gov
Sleep Health Profiles Predicting Impaired Cognition and Depressive Symptoms in Older Adults: Extending Novel Statistical Methods in Multi-Cohort ApplicationsNIHNational Institute on Aging2021$1,968,065August 1, 2017March 31, 2024WALLACE, MEREDITH JOANNE LOTZreporter.nih.gov
Uncovering the dual anabolic and anti-catabolic effects of Pyk2 inhibition on bone massNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,948,578August 22, 2022July 31, 2027BRUZZANITI, ANGELAreporter.nih.gov
Different Roles for Colony Stimulating Factor 1 Isoforms in Anabolic Therapy for Low Bone MassNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,938,339July 10, 2023June 30, 2028INSOGNA, KARL LEONARDreporter.nih.gov
A randomized, double-blind, placebo-controlled, clinical trial of a probiotic/prebiotic supplement for the dietary management of age-related bone loss.NIHNational Institute on Aging2023 to 2025$1,914,574August 1, 2023April 30, 2028SAHNI, SHIVANIreporter.nih.gov
Different consequences of cellular aging in cortical versus cancellous bone- ResubmissionNIHNational Institute on Aging2021 to 2025$1,910,179April 1, 2021December 31, 2026ALMEIDA, MARIA JOSEreporter.nih.gov
Identification of Genes Regulating PTH-Mediated Skeletal StrengthNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,905,956September 1, 2019July 31, 2025ACKERT-BICKNELL, CHERYL LYNNEreporter.nih.gov
The Microbiome and Bone StrengthNIHNational Institute on Aging2023 to 2025$1,905,914May 15, 2021February 28, 2027HERNANDEZ, CHRISTOPHER JOHNreporter.nih.gov
Automatic, Opportunistic Surveillance of Hip Bone Fragility in X-ray ImagesNIHNational Institute on Aging2023 to 2024$1,884,699June 1, 2023February 28, 2026VAZIRI, ASHKANreporter.nih.gov
Novel mechanisms of muscle and bone loss with HIV infection, antiretroviral therapy, and aging.NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,882,652April 1, 2023March 31, 2028MCGEE-LAWRENCE, MEGHAN E.reporter.nih.gov
Circadian Rest-Activity Rhythms, Metabolomic Profiles, and Incidence of Alzheimer's Disease and Related Dementia in Older Men and WomenNIHNational Institute on Aging2021 to 2023$1,876,331April 15, 2020March 31, 2026XIAO, QIANreporter.nih.gov
Bisphosphonate Use to Mitigate Bone Loss Secondary to Bariatric SurgeryNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,868,909May 20, 2022April 30, 2028BEAVERS, KRISTEN MARIEreporter.nih.gov
Role of Glutamine Metabolism During Osteoblast Differentiation and Bone FormationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,868,808April 1, 2018April 30, 2029KARNER, COURTNEY MICHAELreporter.nih.gov
Bone Quality Assessment with a Novel Three-Bore Magnet Extremity MRI ScannerNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,862,401February 1, 2020November 30, 2026ACKERMAN, JEROME Lreporter.nih.gov
Immunometabolic regulation of bone inflammagingNIHNational Institute on Aging2022 to 2025$1,850,428June 15, 2022March 31, 2027DIXIT, VISHWA DEEPreporter.nih.gov
ENPP1 regulation of mammalian bone massNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,815,638June 1, 2022April 30, 2027BRADDOCK, DEMETRIOSreporter.nih.gov
The cell metabolism basis for bone complications in type I diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,809,435May 1, 2021April 30, 2026LONG, FANXINreporter.nih.gov
Parathyroid hormone (PTH) modulates lipid metabolism in the skeletal nicheNIHNational Institute on Aging2021 to 2025$1,808,961September 30, 2020September 30, 2025RENDINA-RUEDY, ELIZABETHreporter.nih.gov
Regulation of bone homeostasis and remodeling by long noncoding RNA Malat1NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,795,657July 1, 2021February 28, 2027ZHAO, BAOHONGreporter.nih.gov
Contraceptive DMPA-induced bone loss: A novel source of toxic metal lead exposure in young womenNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,781,100September 1, 2023June 30, 2027UPSON, KRISTENreporter.nih.gov
Role of glucocorticoid-suppression of preosteoclast PDGF-BB in skeletal angiogenesisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,776,034April 1, 2021March 31, 2026CRANE, JANETreporter.nih.gov
Mechanisms of bone fragility in Autosomal Dominant Osteopetrosis type II: from human to mouse and backNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,769,891September 1, 2022May 31, 2026CHARLES, JULIA Freporter.nih.gov
Mechanisms Mediating Osseointegration of 3D Printed Titanium ConstructsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,766,718January 7, 2019December 31, 2024BOYAN, BARBARA D.reporter.nih.gov
Fractured Schedules: Skeletal Effects of Acute and Chronic Night Shift WorkNIHNational Heart, Lung, and Blood Institute2021 to 2025$1,761,892July 1, 2021June 30, 2027SWANSON, CHRISTINE Mreporter.nih.gov
3-D Visualization and Prediction of Vertebral FracturesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,757,904July 7, 2008August 31, 2025MORGAN, ELISE Freporter.nih.gov
Incorporating Nutrition, Vests, Education, and Strength Training in Bone Health (INVEST in Bone Health)NIHNational Institute on Aging2021 to 2023$1,749,653September 15, 2019April 30, 2026BEAVERS, KRISTEN MARIEreporter.nih.gov
Clickable Microgel Scaffolds for MSC Expansion and DeliveryNIHNational Institute of Dental & Craniofacial Research2021 to 2023$1,727,811March 5, 2019February 28, 2025ANSETH, KRISTI S.reporter.nih.gov
Identification of Metabolomic Profiles for Sarcopenia Traits in Older Whites and BlacksNIHNational Institute on Aging2021 to 2023$1,718,289September 1, 2019April 30, 2025ZHAO, QIreporter.nih.gov
Role of Macrophage in Osteoimmunology with AgingNIHNational Institute on Aging2022 to 2025$1,705,474May 1, 2022January 31, 2027YAO, ZHENQIANGreporter.nih.gov
Molecular and cellular mechanisms of the actin cytoskeleton organization and functionNIHNational Institute of General Medical Sciences2022 to 2025$1,704,179September 1, 2022August 31, 2026KUDRYASHOV, DMITRIreporter.nih.gov
Novel Small Molecule for Improved Dental Implant OsseointegrationNIHNational Institute of Dental & Craniofacial Research2021 to 2022$1,700,486September 16, 2021August 31, 2025MORANO, MARIA INESreporter.nih.gov
A dual proteolytic axis regulates osteoclast-mediated bone coupling activityNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,691,976September 15, 2019May 31, 2029WEISS, STEPHEN Jreporter.nih.gov
Quantitative bone radiomics using Ultra-High Resolution CTNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$1,691,144July 1, 2021March 31, 2026ZBIJEWSKI, WOJCIECH BARTOSZreporter.nih.gov
Assessment of Frailty Phenotype and Functional Limitations to Improve Prediction of Subsequent Health Care Utilization in Older Community-Dwelling AdultsNIHNational Institute on Aging2021 to 2023$1,675,230September 1, 2020May 31, 2024ENSRUD, KRISTINEreporter.nih.gov
Molecular and cellular mechanisms of prevention of bone loss by beta blockersNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,665,909September 21, 2022August 31, 2027MOTYL, KATHERINE JEANreporter.nih.gov
MRI of Proximal Femur Bone Quality for Monitoring Short-Term Response to Osteoporosis TherapyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,665,189May 1, 2019April 30, 2025CHANG, GREGORYreporter.nih.gov
Regulation of age-related bone loss by PKIgammaNIHNational Institute on Aging2021 to 2024$1,661,587July 15, 2020April 30, 2026GREENFIELD, EDWARD M.reporter.nih.gov
Development of a Photoacoustic Quantitative Ultrasound (PAQUS) device for clinical useNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,654,020September 15, 2017August 31, 2025MORRIS, RICHARD FRANKLINreporter.nih.gov
Endocrine disrupting chemical mixtures and bone health in adolescenceNIHNational Institute of Environmental Health Sciences2023 to 2025$1,653,682September 3, 2021June 30, 2027BUCKLEY, JESSIE Preporter.nih.gov
Lrp5 and Lrp6 signaling in bone mechanotransduction and metabolismNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,651,147September 30, 2005August 31, 2029ROBLING, ALEXANDER Greporter.nih.gov
Precision medicine approaches to renal osteodystrophyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2024$1,649,119September 1, 2022June 30, 2027NICKOLAS, THOMAS L.reporter.nih.gov
Role of Cellular Senescence in the Bone-Brain InterplayNIHNational Institute on Aging2021 to 2024$1,637,500August 15, 2020May 31, 2026WAN, MEIreporter.nih.gov
Determining cell-specific mechanisms that drive aberrant bone regeneration in Down syndromeNIHNational Institute on Aging2023$1,633,451September 1, 2023August 31, 2026DAWSON, LINDSAY Areporter.nih.gov
Muscle Quantity, Quality, Function, and Biomarker Associations with Longitudinal Preservation of Bone Microarchitecture and Bone Strength in Older AdultsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$1,610,219September 15, 2025August 31, 2029STROTMEYER, ELSA S.reporter.nih.gov
The impact of age-related changes in osteoclast function on the skeletonNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,594,526June 15, 2021March 31, 2026WEIVODA, MEGAN M.reporter.nih.gov
Role and Mechanism of Action of Ksr2, an Obesity and Type 2 Diabetes Gene, in Bone MetabolismNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,588,939January 1, 2003December 31, 2026MOHAN, SUBBURAMANreporter.nih.gov
A Systems Genetics Approach to Identify BMD GenesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,580,421April 1, 2018February 29, 2024GERSTENFELD, LOUIS CHARLESreporter.nih.gov
Environmental Chemicals, Adiposity, and Bone Accrual Across AdolescenceNIHNational Institute of Environmental Health Sciences2021 to 2023$1,567,855February 1, 2019January 31, 2026FLEISCH, ABBYreporter.nih.gov
Changes in Bone Quality, Sarcopenia and Fat Distribution in HIV/HCV Patients after HCV TherapyNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,553,826December 1, 2017November 30, 2024LO RE, VINCENTreporter.nih.gov
Origins of Skeletal Fragility in Type 1 DiabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,553,049July 25, 2023April 30, 2027FOWLKES, JOHN Lreporter.nih.gov
Raman spectroscopic platform for transcutaneous monitoring of bone qualityNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,549,080July 1, 2016April 30, 2028BERGER, ANDREW Jreporter.nih.gov
Relating phthalate and metals exposure during pregnancy and perimenopause to bone health and body composition in midlifeNIHNational Institute of Environmental Health Sciences2021 to 2025$1,521,797September 10, 2020June 30, 2027WATKINS, DEBORAH Jreporter.nih.gov
Bone Quality in Patients with Long-Standing Type 1 DiabetesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,502,592August 17, 2022July 31, 2027CARBALLIDO-GAMIO, JULIOreporter.nih.gov
Sustained regulation of hypothalamus-pituitary-ovary hormones with tissue-engineered ovarian constructs as a treatment for osteoporosis in femalesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,502,202May 15, 2023March 31, 2028SAUL, JUSTINreporter.nih.gov
Muscle regulation of bone functionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,481,503April 1, 2019February 28, 2025KARSENTY, GERARDreporter.nih.gov
Large-Scale Genetic Analysis of Bone Strength in Diversity Outbred MiceNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,473,451April 15, 2024January 31, 2029FARBER, CHARLES Rreporter.nih.gov
"Establishing Pathways for Endothelial Support of Bone Formation with SLIT3"NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,465,497April 1, 2020February 28, 2025GREENBLATT, MATTHEW BLAKEreporter.nih.gov
CT-Based Modeling of Bone Micro-Architecture and Fracture-Risk in COPDNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,458,211July 1, 2018April 30, 2025SAHA, PUNAM K.reporter.nih.gov
Mechanistic basis of the role of Cbx3 in negatively regulating osteoclast differentiation through epigenetic modificationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,457,862August 6, 2019July 31, 2025LI, YI-PINGreporter.nih.gov
HIFs in osteocytesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$1,453,169April 1, 2019November 30, 2024YELLOWLEY-GENETOS, CLARE Ereporter.nih.gov
Heterogeneity of bone marrow cavities shaping the hematopoietic microenvironmentNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,449,323December 1, 2023November 30, 2027LIN, CHARLES P.reporter.nih.gov
RAMP-altered class B GPCR hormone binding and signalingNIHNational Institute of General Medical Sciences2021 to 2024$1,439,860September 26, 2012August 31, 2025PIOSZAK, AUGEN Areporter.nih.gov
Pathophysiologic mechanisms during initiation of medication related osteonecrosis of the jawsNIHNational Institute of Dental & Craniofacial Research2021 to 2024$1,434,195September 15, 2009August 31, 2025TETRADIS, SOTIRIOSreporter.nih.gov
MRI Assessment of Hip Fracture Risk and Therapy Response in HIV/HCV CoinfectionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,420,013September 11, 2019July 31, 2025RAJAPAKSE, CHAMITH SUDESHreporter.nih.gov
Effects of bimagrumab on body composition, insulin sensitivity, and bone in adults with obesityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2024$1,410,166August 3, 2023April 30, 2029HAINES, MELANIE SCHORRreporter.nih.gov
IgSF11 Signaling Controls Osteoclast Maturation and Pathogenic Bone LossNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,408,550January 1, 2022November 30, 2026CHOI, YONGWONreporter.nih.gov
Arcuate ERa Signaling in Central Control of Female Bone MetabolismNIHNational Institute on Aging2021 to 2023$1,405,068September 30, 2019May 31, 2024INGRAHAM, HOLLY A.reporter.nih.gov
Development and Application of Organelle Chemotype Fingerprinting for the Functional Investigation of Organellar ChlorideNIHNational Institute of General Medical Sciences2022 to 2025$1,388,647August 1, 2022November 3, 2025LEUNG, KA HOreporter.nih.gov
The Role of TRAPPC9 in Osteoclast Differentiation and FunctionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,384,525August 1, 2020January 31, 2026SAFADI, FAYEZ Freporter.nih.gov
Predicting Fast Bone Mineral Density Decline and Fracture Across the Menopause TransitionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,372,258May 6, 2020December 31, 2026SHIEH, ALBERTreporter.nih.gov
Role of IL-17 receptor A in aging bone remodelingNIHNational Institute on Aging2023 to 2025$1,353,817August 1, 2023April 30, 2028DRISSI, MOULAY HICHAMreporter.nih.gov
DOES LIFESTYLE INTERVENTION IN OBESE OLDER ADULTS IMPROVE BONE QUALITY?NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,351,102June 1, 2017May 31, 2025VILLAREAL, DENNIS T.reporter.nih.gov
Proteoglycans and age-related deterioration of bone toughnessNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,350,478July 1, 2019June 30, 2025WANG, XIAODUreporter.nih.gov
Menopause-related increase in gut leak and its relation to immune activation, bone density decline and fracturesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2024$1,347,632January 25, 2023December 31, 2028SHIEH, ALBERTreporter.nih.gov
Fractures and bone disease in living kidney donorsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,346,118July 9, 2020October 31, 2024KUMAR, RAJIVreporter.nih.gov
Spatial Control of Bone Remodeling by Gap Junction-Communicated cAMPNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,341,582March 1, 2013February 28, 2025STAINS, JOSEPH P.reporter.nih.gov
Endocrine disrupting chemical mixtures and bone health in adolescenceNIHNational Institute of Environmental Health Sciences2021 to 2022$1,328,874September 3, 2021June 30, 2023BUCKLEY, JESSIE Preporter.nih.gov
Targeting Nitrate-Nitrite-NO pathway for Ameliorating Muscle and Bone Comorbidities in Duchenne Muscular DystrophyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,321,811September 15, 2020August 31, 2025LI, HONGSHUAIreporter.nih.gov
Role of LINC-mediated Mechanosignaling in MSC AgingNIHNational Institute on Aging2021 to 2024$1,316,989March 1, 2020January 31, 2026UZER, GUNESreporter.nih.gov
The impact of glomerular disorders on bone quality and strengthNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,315,396September 21, 2018July 31, 2025NICKOLAS, THOMAS L.reporter.nih.gov
Optimization of a Novel Thread Geometry for Various Orthopedic Surgery ApplicationsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,314,888September 20, 2021August 31, 2025FAUTH, ANDREW RAYreporter.nih.gov
The role of Piezo1 in bone homeostasis and mechanotransductionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,314,192August 17, 2020June 30, 2026XIONG, JINHUreporter.nih.gov
Role of Mitochondrial Quality Control in Bone Homeostasis and DiseaseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,302,642August 1, 2022July 31, 2027KIM, HA-NEUIreporter.nih.gov
Modifying the mechanotransduction of bone by targeting purinergic receptorsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,301,223September 1, 2020August 31, 2025GARDINIER, JOSEPH DANIELreporter.nih.gov
Osteocyte Control of Bone RemodelingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,294,128September 29, 2003March 31, 2027O'BRIEN, CHARLES Areporter.nih.gov
Sexually dimorphic regulation of bone mass by the X-linked histone modifier KDM5CNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,285,876August 19, 2024May 31, 2029YANG, TAOreporter.nih.gov
Targeting the ubiquitin-proteasome pathway to reverse catabolic action of PTH in boneNIHNational Institute on Aging2021 to 2024$1,284,307September 30, 2020June 30, 2026WANG, BINreporter.nih.gov
The Role of Proline Metabolism During Osteoblast Differentiation and Bone FormationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,276,069August 10, 2020July 31, 2025KARNER, COURTNEY MICHAELreporter.nih.gov
Severe Trauma Provokes Pathologic Continuum of Plasmin ActivationNIHNational Institute of General Medical Sciences2021 to 2023$1,272,869April 1, 2019December 31, 2024SCHOENECKER, JONATHANreporter.nih.gov
MOLECULAR MECHANISMS OF V-ATPASES: ASSEMBLY, BIOGENESIS, REGULATION, AND FUNCTIONNIHNational Institute of General Medical Sciences2022 to 2024$1,267,302August 1, 2022June 30, 2027FU, TIANMINreporter.nih.gov
The Microbiome and Bone StrengthNIHNational Institute on Aging2021 to 2022$1,254,262May 15, 2021February 28, 2026HERNANDEZ, CHRISTOPHER JOHNreporter.nih.gov
Gene Therapy to Treat Ethanol-induced Osteoporosis Associated with Aldehyde Dehydrogenase 2 Deficiency in Post-menopausal East Asian WomenNIHNational Institute on Alcohol Abuse and Alcoholism2025$1,253,597July 1, 2020August 31, 2027CRYSTAL, RONALD Greporter.nih.gov
Determining Bone Loss and Bone Mineral Density Recovery Following Repeat Pregnancy/Lactation Among HIV Women on ARTNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,247,890June 1, 2023May 31, 2024FOWLER, MARY GLENNreporter.nih.gov
Does Creating Person-specific Precision Thresholds Enhance the Ability of a Single Bone Density Measure to Predict Fractures in Minority Women?NIHNational Institute on Aging2024 to 2025$1,246,122December 1, 2023November 30, 2027WU, QINGreporter.nih.gov
Structural, Molecular and Functional Specialization in Osteocyte MechanosensingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,243,783July 11, 2018April 30, 2026SCHAFFLER, MITCHELL Breporter.nih.gov
Romosozumab as an adjunct to physiologic estrogen replacement in adolescents and young adults with functional hypothalamic amenorrheaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$1,232,978August 6, 2024April 30, 2029MILLER, KAREN Kreporter.nih.gov
Role of Gut Microbiota in Bone Mass Heritability and Skeletal Response to PTHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,230,972March 6, 2019January 31, 2024PACIFICI, ROBERTOreporter.nih.gov
VITamin D and OmegA-3 TriaL (VITAL): Interrelationship of Vitamin D and Vitamin K on BoneNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,210,116August 1, 2012July 31, 2024LEBOFF, MERYL SUSANreporter.nih.gov
Heterogeneous pathways to bone strength decline and hip fractureNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,209,978April 15, 2024January 31, 2029JEPSEN, KARL Jreporter.nih.gov
How bisphosphonates affect bone matrix and remodeling: implications for atypical femoral fracturesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,209,492May 12, 2023March 31, 2028ROSS, RYAN DEEreporter.nih.gov
Clinical Biomechanics of Hip FractureNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,184,778April 15, 2020March 31, 2024KOPPERDAHL, DAVIDreporter.nih.gov
Impact of Concurrent Initiation of DMPA Contraception and Tenofovir PrEP on Bone Loss in Young WomenNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021$1,179,700May 17, 2017March 31, 2024HEFFRON, RENEE A.reporter.nih.gov
The Role of miR-219a-5p in Bone MetabolismNIHNational Institute on Aging2021 to 2024$1,178,717May 1, 2020January 31, 2026MONROE, DAVID Greporter.nih.gov
Tribbles homolog 3 and BMP-2 induced bone formationNIHNational Institute of Dental & Craniofacial Research2021 to 2025$1,175,825June 8, 2018May 31, 2030LEE, MINreporter.nih.gov
Novel Agonists and Inverse Agonists for B-Family GPCRsNIHNational Institute of General Medical Sciences2021 to 2023$1,173,220September 1, 1997January 31, 2024GELLMAN, SAMUEL H.reporter.nih.gov
Processes mediated by polypeptidesNIHNational Institute of General Medical Sciences2024 to 2025$1,163,046February 1, 2024January 31, 2029GELLMAN, SAMUEL H.reporter.nih.gov
Skeletal Microstructure - Racial Differences and Genetic ContributorsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,160,360August 1, 2018July 31, 2024WALKER, MARCELLA DONOVANreporter.nih.gov
Osteocyte Mechanotransduction and the Gabapentin-Sensitive Matrix-Channel Tethering ComplexNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,159,167September 20, 2018June 30, 2025THOMPSON, WILLIAM ROYreporter.nih.gov
Chronic sleep deficiency as a cause of bone loss in agingNIHNational Institute on Aging2024 to 2025$1,158,407April 1, 2024March 31, 2028EVERSON, CAROL Areporter.nih.gov
2/1 - Mongolian Center for Environmental & Occupational Health - MongoliaNIHFogarty International Center2022 to 2025$1,156,208June 13, 2022February 28, 2027DAMBADARJAA, DAVAALKHAM -reporter.nih.gov
Determinants of bone microarchitectural compromise in youth with type 1 diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,152,121September 12, 2019June 30, 2025MITCHELL, DEBORAH MICHELLEreporter.nih.gov
Mechanisms Underlying the Bone Modeling Effects of Combined Anabolic/Antiresorptive AdministrationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,145,186April 1, 2019March 31, 2024LEDER, BENJAMIN Zreporter.nih.gov
EOI:: IMPLEMENTING THE PRESIDENTS DEPARTMENT OF GOVERNMENT EFFICIENCY COST EFFICIENCY INITIATIVE (MARCH 19, 2025):: EOI PARTIAL TERMINATION FOR CONVENIENCE AGREEMENT FOR NIAMS INFORMATION TECHNOLOGY SNIHNational Heart, Lung, and Blood Institute2025$1,114,680September 25, 2024June 30, 2026MILLER, CAROLreporter.nih.gov
Identifying Osteoporosis Genes by Whole Genome Sequencing and Functional Validation in Zebra FishNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,107,437September 1, 2017July 31, 2025HSU, YI-HSIANGreporter.nih.gov
Effects of DHEA and exercise on bone marrow fat in postmenopausal womenNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,103,385July 1, 2021May 31, 2026JANKOWSKI, CATHERINE Mreporter.nih.gov
Signaling mediators of CCL2/CCR2 and natural product discoveryNIHNational Institute of General Medical Sciences2023 to 2025$1,083,333May 1, 2023April 30, 2028WANG, PIWENreporter.nih.gov
Influence of Spinal Loading on Vertebral FractureNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,073,920September 14, 2018August 31, 2025BOUXSEIN, MARY Lreporter.nih.gov
VITamin D OmegA-3 TriaL (VITAL): Fractures, Vitamin D and Genetic MarkersNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,064,382June 1, 2018April 30, 2024LEBOFF, MERYL SUSANreporter.nih.gov
Improving Fracture Healing with Active Plating TechnologyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,062,489September 22, 2021March 31, 2024BOTTLANG, MICHAELreporter.nih.gov
Diverse effects of somatopause and aging on the skeletonNIHNational Institute on Aging2021 to 2022$1,059,992September 15, 2018April 30, 2024YAKAR, SHOSHANAreporter.nih.gov
Evaluating the Association between Cardiometabolic Health Over the Lifespan and Vertebral StrengthNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2024$1,059,026March 1, 2023November 15, 2024WRIGHT, NICOLE Creporter.nih.gov
HIF-2alpha, a Novel Regulator of OsteoblastogenesisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,057,667January 11, 2019December 31, 2023SCHIPANI, ERNESTINAreporter.nih.gov
Bone In CKD Alkali Response Pilot Trial (BICARb Pilot Trial)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2024$1,036,297August 15, 2022July 31, 2025REIDY, KIMBERLY JEANreporter.nih.gov
Impact of Tetracycline Antibiotics on Skeletal MaturationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2024$1,031,114April 1, 2023March 31, 2028WESTWATER, CAROLINEreporter.nih.gov
Interactions of PTH and Wnt signaling in bone formationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,029,029May 1, 2019April 30, 2024WU, JOY Yreporter.nih.gov
Skeletal Effects of Type 1 DiabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,026,893September 12, 2019August 31, 2025AKHTER, MOHAMMED PERVEZreporter.nih.gov
Early Life Phthalate and Perfluoroalkyl Substance Exposures and Childhood Bone HealthNIHNational Institute of Environmental Health Sciences2021 to 2023$1,020,341January 1, 2019June 30, 2023BUCKLEY, JESSIE Preporter.nih.gov
A critical role for PLD1 in osteoclast fusionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,016,484August 1, 2019July 31, 2025DU, GUANGWEIreporter.nih.gov
Regulation of PTH secretion by TRPC1NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,013,396April 1, 2019March 31, 2024TSIOKAS, LEONIDASreporter.nih.gov
Marrow Adipose Compartment Physiology in Caloric Restriction and AgingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,012,616April 5, 2019March 31, 2025STYNER, MAYA SHALEVreporter.nih.gov
Osteocyte CaMKII as a Critical Regulator of Bone Physiology and AnabolismNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,007,915March 21, 2018March 31, 2030STAINS, JOSEPH P.reporter.nih.gov
A Multi-robot System for Semi-automated Image-guided Vertebral AugmentationNIHNational Institute of Biomedical Imaging and Bioengineering2024 to 2025$1,005,979May 10, 2024February 29, 2028UNBERATH, MATHIASreporter.nih.gov
Renewed bone remodeling after pausing long-term bisphosphonate use: Does it replace regions of impaired bone quality and restore mechanical integrity?NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$999,606September 5, 2023March 31, 2029SCHAFFLER, MITCHELL Breporter.nih.gov
Transdermal estrogen for the treatment of bone loss in women with anorexia nervosaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$997,598September 1, 2019June 30, 2025FAZELI, POUNEH KHADEJEHreporter.nih.gov
Mentoring in Endocrine and Metabolic Abnormalities in HIV and AgingNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$968,104July 1, 2015July 31, 2026BROWN, TODD Treporter.nih.gov
Molecular Mechanisms of LRRK1 Regulation of Bone HomeostasisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$957,231January 1, 2022December 31, 2026XING, WEIRONGreporter.nih.gov
Skeletal Health in Youth with Type 1 Diabetes and Gender DiversityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$955,585September 12, 2019March 12, 2025RUBIN, MISHAELA Rreporter.nih.gov
Mentoring Research in Non-infectious Complications of HIVNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$939,620September 17, 2021August 31, 2026YIN, MICHAEL Treporter.nih.gov
Progression and etiology of cortical porosity in diabetic bone diseaseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$930,473March 1, 2017February 29, 2024KAZAKIA, GALATEIA Jreporter.nih.gov
A feasibility study of alendronate therapy for osteonecrosis of the femoral head in adults with sickle cell diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$925,439September 20, 2021August 31, 2026ADESINA, OYEBIMPE OLUYEMISIreporter.nih.gov
Dynamics of Bone ECM Assembly and ResorptionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$924,291July 18, 2024June 30, 2029DALLAS, SARAH Lreporter.nih.gov
Renal Osteodystrophy Precision Medicine ProjectNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2023$898,650September 16, 2022May 31, 2024NICKOLAS, THOMAS L.reporter.nih.gov
Changes in Periosteal and Endocortical Width Across the Menopausal TransitionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$890,732August 1, 2018July 31, 2024JEPSEN, KARL Jreporter.nih.gov
Bone Deficits and Mechanical Loading in Ambulatory Cerebral PalsyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$865,056August 22, 2018May 31, 2025WREN, TISHYA A Lreporter.nih.gov
Antagonism of RANKL signaling by estrogen in osteoclastsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$864,952March 22, 2024February 28, 2029ALMEIDA, MARIA JOSEreporter.nih.gov
The Skeleton of Lateral Meningocele SyndromeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2023$862,047July 18, 2018December 31, 2024CANALIS, ERNESTOreporter.nih.gov
The Nmp4 Anti-Anabolic Bone Axis R01AR070144-01A1NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$851,133August 15, 2018July 31, 2025BIDWELL, JOSEPH Preporter.nih.gov
Osseosurface Electronics: Chronic Wireless Battery Interfaces for Osteoporosis Treatment and DiscoveryNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$846,242April 15, 2024February 28, 2029GUTRUF, PHILIPPreporter.nih.gov
Hypercalciuria and Abnormal Bone in the Genetic Hypercalciuric Stone-Forming RatsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$841,498April 1, 2024January 31, 2029LI, QIAOLIreporter.nih.gov
Ultra-Resolution Imaging on Standard Clinical CTNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2022$838,566August 2, 2020October 2, 2023FU, LINreporter.nih.gov
Contribution of chromosome versus gonadal sex to bone mass and strengthNIHNational Institute on Aging2022 to 2023$832,125July 15, 2022March 31, 2025PLOTKIN, LILIAN IRENEreporter.nih.gov
Bone neuro-mechanosignaling and inflammation: New players in diabetic osteopeniaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$820,919March 1, 2018December 31, 2023THI, MIA Mreporter.nih.gov
Image-Guided Workstation and Tools for Bone DefectsNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2022$810,752September 30, 2013August 1, 2024ARMAND, MEHRANreporter.nih.gov
Adding bone microarchitecture and strength measures to the STRONG BONES randomized trial examining risedronate use to mitigate bone loss after bariatric surgeryNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$808,372February 23, 2024January 31, 2028WEAVER, ASHLEYreporter.nih.gov
Bone Water and Mineralization Measured by Nuclear Magnetic ResonanceNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$806,679September 9, 2003November 30, 2024WEHRLI, FELIX Wreporter.nih.gov
Nuclear Events in PTHR1 Action on BoneNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2024$802,918December 1, 1994August 1, 2024PARTRIDGE, NICOLA Creporter.nih.gov
Deciphering Mechanisms of Nitrogen-Containing BisphosphonatesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$802,912February 1, 2022January 31, 2025SURFACE, LAUREN ELIZABETHreporter.nih.gov
PPARgamma Deacetylation in the Restoration of Metabolic HomeostasisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$800,000December 1, 2017November 30, 2022QIANG, LIreporter.nih.gov
The Mechanistic Effects of Combined Testosterone Therapy and Exercise on Axial Bone and Muscle Post-Hip FractureNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$790,314June 7, 2019August 31, 2024HANNAN, MARIAN T.reporter.nih.gov
Osteogenic and angiogenic tissue regeneration to accelerate secondary bone healing during agingNIHNational Institute on Aging2021 to 2023$788,430August 1, 2019April 30, 2025DRISSI, MOULAY HICHAMreporter.nih.gov
Bone Health in Patients with Urinary Stone DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$772,217January 15, 2022November 30, 2026GANESAN, CALYANIreporter.nih.gov
Nuclear Events in PTHR1 Action on BoneNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$769,300December 1, 1994April 30, 2027PARTRIDGE, NICOLA Creporter.nih.gov
A novel regulating pathway in osteoclastogenesis and arthritic bone resorptionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$756,427April 1, 2018January 31, 2024PARK-MIN, KYUNG-HYUNreporter.nih.gov
Reversing Skeletal Aging by Restoring Functional Skeletal Stem Cell DiversityNIHNational Institute on Aging2023 to 2025$742,021April 1, 2021December 31, 2025AMBROSI, THOMAS HANSreporter.nih.gov
Epigenetic Regulation of Orofacial Bone Homeostasis and Aging by KDM4BNIHNational Institute of Dental & Craniofacial Research2021 to 2022$737,295September 10, 2018May 31, 2024WANG, CUN-YUreporter.nih.gov
A patient-specific computational technique to predict spine injury risks associated with physical activitiesNIHNational Institute on Aging2021 to 2025$737,209April 15, 2021June 30, 2026REZAEI, ASGHARreporter.nih.gov
Bone Health in Adults with Type 1 DiabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$733,688September 13, 2019February 1, 2024SHAH, VIRAL Nreporter.nih.gov
Bone microarchitecture and bone strength relationships to muscle quantity, quality and function in older adultsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2023$729,786September 18, 2019February 28, 2025CAULEY, JANE ANNreporter.nih.gov
Trigeminal Afferents Regulation of Apical Periodontitis DevelopmentNIHNational Institute of Dental & Craniofacial Research2021 to 2022$720,754August 1, 2018July 31, 2024DIOGENES, ANIBALreporter.nih.gov
PFAS and bone health over the life course in Hispanic/Latinos: emerging risk factors and underlying mechanismsNIHNational Institute of Environmental Health Sciences2025$709,575January 3, 2025December 31, 2025CHATZI, VAIA LIDAreporter.nih.gov
An integrated nano- and micro-indentation system for musculoskeletal tissue and biomaterialsNIHOffice of the Director, National Institutes of Health2023$691,040April 1, 2023March 31, 2025LIU, XIAOWEI SHERRYreporter.nih.gov
Leveraging Context-Specific eQTL to Inform BMD GWASNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$685,866August 15, 2025July 31, 2030FARBER, CHARLES Rreporter.nih.gov
Sleep Health Profiles Predicting Impaired Cognition and Depressive Symptoms in Older Adults: Extending Novel Statistical Methods in Multi-Cohort ApplicationsNIHNational Institute on Aging2024$671,852August 1, 2017March 31, 2026WALLACE, MEREDITH JOANNE LOTZreporter.nih.gov
MRI Bone Texture: A Novel Biomarker for Assessment of Bone Quality and Prediction of Complications in Patients Having Spine Fusion SurgeryNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$665,177August 1, 2022May 31, 2027STEIN, EMILY MARGARETreporter.nih.gov
Connexin channels in transducing mechanical signals in boneNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$657,580August 1, 2018July 31, 2024JIANG, JEAN Xreporter.nih.gov
Skeletal Functions of Polycystins and TAZNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$655,424August 24, 2018June 30, 2024XIAO, ZHOUSHENGreporter.nih.gov
Limited-duration anabolic therapy in postmenopausal osteoporosisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$654,829September 20, 2021August 31, 2025LEDER, BENJAMIN Zreporter.nih.gov
Bone Quality Assessment During Breast Cancer Treatment via Wrist Tomosynthesis in the Mammography SettingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$651,514June 16, 2025May 31, 2030YENI, YENER Nreporter.nih.gov
Role and Mechanism of Claudin-11 Action and Signaling in BoneNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2023$641,377August 1, 2017July 31, 2024MOHAN, SUBBURAMANreporter.nih.gov
Influence of SSRI Use During Pregnancy and Lactation on Maternal Bone HealthNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$638,867July 20, 2018April 30, 2024HERNANDEZ, LAURA LORRAINEreporter.nih.gov
Utilizing spatially-informed cell-specific multicellular genome-scale metabolic models to unveil the mechanisms that regulate the decline of the ovarian reserveNIHNational Institute on Aging2024$625,898September 1, 2024August 31, 2027PENALVER BERNABE, BEATRIZreporter.nih.gov
Subchondral Bone Cavities in Osteoarthritis PainNIHNational Institute on Aging2024$620,588September 30, 2020August 31, 2025CAO, XUreporter.nih.gov
A Biophotonics Platform for Mechanotransduction and Metabolic MicroscopyNIHNational Institute of General Medical Sciences2021 to 2022$618,002June 1, 2019March 31, 2025VENUGOPALAN, VASANreporter.nih.gov
Long-Term Approaches to Treating OsteoporosisNIHNational Institute on Aging2023 to 2025$617,788September 30, 2023May 31, 2027NAYAK, SMITAreporter.nih.gov
A Neurosurgical Robotic System for Minimally Invasive Spinal Fusion of Osteoporotic Vertebrae Using Flexible Pedicle ScrewsNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2023$606,790April 1, 2021December 31, 2024ALAMBEIGI, FARSHIDreporter.nih.gov
Molecular mechanisms of lysosome secretion in osteoclasts and bone HomeostasisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$592,733August 1, 2019July 31, 2025ZHAO, HAIBOreporter.nih.gov
Metabolic regulation of osteoclast differentiation and bone resorptionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$588,302February 1, 2025January 31, 2030KARNER, COURTNEY MICHAELreporter.nih.gov
Combined Anabolic Therapy in Postmenopausal OsteoporosisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024$587,840September 23, 2024August 31, 2027LEDER, BENJAMIN Zreporter.nih.gov
The Gut Microbiome and Bone MicroarchitectureNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$581,835May 1, 2012June 30, 2024KIEL, DOUGLAS P.reporter.nih.gov
DHEA augmentation of musculoskeletal adaptations to exercise in older womenNIHNational Institute on Aging2021$575,752July 1, 2017May 31, 2024JANKOWSKI, CATHERINE Mreporter.nih.gov
Bone microarchitecture, diabetes and change in bone mineral density in Puerto Rican adultsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022$538,876August 3, 2018December 31, 2023TUCKER, KATHERINE Lreporter.nih.gov
Study of the Safety, Tolerability, and Efficacy of an iPS Cell-based Therapy for Recessive Dystrophic Epidermolysis Bullosa Delivered with a Spray on Skin DeviceNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023$538,200September 1, 2023August 31, 2025ROOP, DENNISreporter.nih.gov
Mineral Scaffold-Modulated Senescence in Irradiated BoneNIHNational Institute of Dental & Craniofacial Research2025$533,675July 1, 2025March 31, 2030HIXON, KATHERINEreporter.nih.gov
Impact of HIV and antiretroviral initiation on skeletal biologyNIHFogarty International Center2022 to 2023$533,018July 1, 2022June 30, 2025YIN, MICHAEL Treporter.nih.gov
The Impact of Disrupting Sensory Innervation on Tibial Bone MassNIHNational Institute of General Medical Sciences2023 to 2025$532,500August 1, 2023July 31, 2027BECKER, KATHLEEN Areporter.nih.gov
Decoding Methylation Mediated Epigenomic Contributions to Male OsteoporosisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$520,889May 8, 2017March 31, 2023DENG, HONG-WENreporter.nih.gov
Mechanisms of Bone Anabolic and Anticatabolic Activities of ProbioticsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$511,058January 24, 2018December 31, 2022PACIFICI, ROBERTOreporter.nih.gov
Role of Src Kinase in Mechanically-Induced Bone FormationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$503,230March 1, 2017February 28, 2023ROBLING, ALEXANDER Greporter.nih.gov
Resolving the mechanism of osteoclast multinucleation and signaling in bone remodelingNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$498,000September 1, 2024August 31, 2027WHITLOCK, JARRED MARCUSreporter.nih.gov
Multi-omic dissection of clonal hematopoiesis-associated diseasesNIHNational Human Genome Research Institute2024 to 2025$498,000September 17, 2024June 30, 2027YU, ZHIreporter.nih.gov
The impact of age-related changes in osteoclast function on the skeleton (R01)NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$495,592June 15, 2021December 17, 2021WEIVODA, MEGAN Mreporter.nih.gov
Elucidating extragonadal functions of follicle stimulating hormone using genetic approaches in miceNIHNational Institute on Aging2022 to 2023$493,523September 1, 2022June 30, 2026GERMAIN-LEE, EMILY Lreporter.nih.gov
Regulation of Osteoblast Metabolism by Lrp5NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$491,152July 24, 2013June 30, 2022RIDDLE, RYAN Creporter.nih.gov
Bone quality and marrow adiposity in subjects with HIVNIHNational Institute of Allergy and Infectious Diseases2021$487,953December 15, 2016November 30, 2023KAZAKIA, GALATEIA Jreporter.nih.gov
Osteoblast Dopamine Receptor Mediates Diabetic Bone DiseaseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$479,391March 10, 2021February 29, 2024TRACKMAN, PHILIP Creporter.nih.gov
Impacts of parental benzo[a]pyrene exposure on offspring’s bone developmentNIHNational Institute of Environmental Health Sciences2021 to 2023$478,779March 1, 2023March 31, 2025SEEMANN, FRAUKEreporter.nih.gov
Nursing Home Prevention of Injury in Dementia (NH PRIDE)NIHNational Institute on Aging2021$475,896May 1, 2019January 31, 2024BERRY, SARAH DYERreporter.nih.gov
Girk3 in bone biology and diseaseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$473,099May 1, 2023August 31, 2027WEAVER, SAMANTHA Rreporter.nih.gov
Optimizing bone surface targeting of therapeutic antibodies for osteoporosisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$465,663May 6, 2025March 31, 2030GREINEDER, COLIN FREDreporter.nih.gov
Adenosine A2B Receptor in Bone Health and OsteoporosisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$459,607September 1, 2017January 31, 2023VARGHESE, SHYNIreporter.nih.gov
Developing and evaluating bone targeting agents to mimic the skeletal effects of mechanical loadingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2023$457,060September 23, 2022August 31, 2025SATO, TADATOSHIreporter.nih.gov
Diversity Supplement: Talking Back: Leveraging dysfunctional osteoclasts to identify novel pathways of osteoclast-osteoblast communicationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$456,408April 1, 2021March 31, 2023CHARLES, JULIA Freporter.nih.gov
Aging Effects on Mechanoregulation of Osteocytes using Multiscale MultiphysicsNIHNational Institute on Aging2024$456,085June 15, 2024May 31, 2027GANESH, THIAGARAJANreporter.nih.gov
Mechanisms of decreased bone formation with agingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022$455,284September 22, 2022August 31, 2024ALMEIDA, MARIA JOSEreporter.nih.gov
Pixelated scintillators for ultra-high resolution cone-beam CTNIHNational Institute of Biomedical Imaging and Bioengineering2024 to 2025$453,907July 15, 2024June 30, 2027ZBIJEWSKI, WOJCIECH BARTOSZreporter.nih.gov
Mathematical Modeling of the Impacts of Prebiotic Dietary Intervention on Immunomodulation During Estrogen DeficiencyNIHNational Institute on Aging2023 to 2024$453,868April 15, 2023January 31, 2026FORD VERSYPT, ASHLEE NICOLEreporter.nih.gov
Fracture Repair in Aging: Identifying networks by miRNA and mRNA co-sequencingNIHNational Institute on Aging2021 to 2022$451,000September 1, 2021May 31, 2025DELANY, ANNE Mreporter.nih.gov
The role of efferocytic macrophages in bone formationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$445,583September 20, 2021August 31, 2023MCCAULEY, LAURIE K.reporter.nih.gov
The Regulatory Mechanisms of OsteoclastsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$445,217September 1, 2025August 31, 2030PARK-MIN, KYUNG-HYUNreporter.nih.gov
Using Established Leptin Signaling Mutants to Study Cell Physiology and Bone Development in ZebrafishNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$443,905April 19, 2021April 18, 2025LONDRAVILLE, RICHARD LYLEreporter.nih.gov
Molecular Regulation of MSC fate Decision and Bone Formation by PGC-1aNIHNational Institute of Dental & Craniofacial Research2021$442,451February 1, 2017January 31, 2022WANG, CUN-YUreporter.nih.gov
ENZYME THERAPY FOR CKD-MBD: BREAKING THE BARRIER OF VASCULAR CALCIFICATIONNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$441,434April 20, 2020July 31, 2023BRADDOCK, DEMETRIOSreporter.nih.gov
Effect of Acetylcholinesterase inhibitors on Bone Metabolism and Fracture Risk Factors among older adults with mild to moderate Alzheimer's DiseaseNIHNational Institute on Aging2023 to 2024$438,632September 1, 2023August 31, 2025LEE, RICHARD HSANG-YANGreporter.nih.gov
XtremeCT II high-resolution peripheral quantitative computed tomography (HR-pQCT) scannerNIHOffice of the Director, National Institutes of Health2022$437,500May 15, 2022May 14, 2024WEAVER, ASHLEYreporter.nih.gov
Establishing a New Model of Bone Health in Formerly Premature IndividualsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2023$433,429July 1, 2022June 30, 2026SUMNER, D RICKreporter.nih.gov
Image Analysis and Machine Learning Methods for Biomarkers of Age-related and Metabolic DiseasesNIHNational Institute of General Medical Sciences2021 to 2024$431,401April 2, 2015July 31, 2025MAKROGIANNIS, SOKRATISreporter.nih.gov
Jawbone is unique: differential responses to growth factor signaling and mechanical loadingNIHNational Institute of Dental & Craniofacial Research2024$429,000September 1, 2024August 31, 2027MISHINA, YUJIreporter.nih.gov
INvestigative Kyphoplasty Efficacy and Safety Trial (INKTEST)NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$425,720September 22, 2021February 29, 2024KALLMES, DAVID Freporter.nih.gov
Musculoskeletal and Pelvic Floor Health in Female Chronic Overlapping Pelvic Pain Conditions (The MSK-PELVIC Study)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2023$419,450September 16, 2022August 31, 2025FITZGERALD, COLLEEN MARIEreporter.nih.gov
Type 2 Diabetes and Bone Health in YouthNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2023$417,598June 20, 2022May 31, 2025BACHA, FIDAreporter.nih.gov
Modifying fragility fracture healing using a gradient-based mechanotransduction fixation approachNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$411,666July 1, 2021June 30, 2024HAST, MICHAEL WILLIAMreporter.nih.gov
Modulating Cellular Bioenergetics to Improve Skeletal HealthNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2023$410,630July 10, 2022May 31, 2025RENDINA-RUEDY, ELIZABETHreporter.nih.gov
Molecular mechanisms of lysosome remodeling in response to cellular stressNIHNational Institute of General Medical Sciences2025$407,562September 1, 2025August 31, 2030YANG, XIreporter.nih.gov
Influence of Vitamin D Binding Protein on Clinical Measures of Vitamin D Status and Bone HealthNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$406,285July 3, 2018April 30, 2024GINSBERG, CHARLESreporter.nih.gov
Precise Bone Density Reference Ranges to Reduce Systematic Disparities in Osteoporosis Healthcare for Hispanic WomenNIHNational Institute on Minority Health and Health Disparities2022 to 2023$405,274December 8, 2021June 30, 2025WU, QINGreporter.nih.gov
Characterization of a humanized mouse model to study HIV and ARV effects on boneNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$404,063September 27, 2021August 31, 2024ROSS, RYAN DEEreporter.nih.gov
An ounce of prevention: stopping menopausal bone loss before it startsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$403,508January 15, 2021December 31, 2023INSOGNA, KARL LEONARDreporter.nih.gov
A novel bone-targeting AAV-mediated gene therapy to promote bone formation in osteoporosisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$403,139August 1, 2021January 31, 2024SHIM, JAE-HYUCKreporter.nih.gov
Effect of protein supplementation during weight loss on older adult bone healthNIHNational Institute on Aging2021 to 2023$401,060February 15, 2019November 30, 2024WEAVER, ASHLEYreporter.nih.gov
Identification of Genes Regulating Bone Matrix Composition and QualityNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$397,144September 15, 2016January 31, 2024ADAMS, DOUGLAS Jreporter.nih.gov
Senile Osteoporosis as a Neuroskeletal DiseaseNIHNational Institute on Aging2021$396,250July 15, 2017May 31, 2023ELEFTERIOU, FLORENTreporter.nih.gov
Intercellular Communication in Paget's Disease of BoneNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$395,076July 1, 2021October 3, 2024HANSEN, MARC Freporter.nih.gov
Influence of Genetic Background on Bone Anabolic Response to Mechanical LoadingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2023$394,166February 1, 2022January 31, 2025SILVA, MATTHEW Jreporter.nih.gov
Denosumab and sequential zoledronic acid to prevent bone loss and maintain bone mass after spinal cord injuryNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$394,087August 1, 2024July 31, 2026SCHNITZER, THOMAS JACKreporter.nih.gov
A new model for spatio-temporal coupling of bone formation and bone resorption governed by osteoclastsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023$393,490September 1, 2020August 31, 2025MISHINA, YUJIreporter.nih.gov
Epigenetic regulation of autophagy and stemness of MSCs in skeletal agingNIHNational Institute on Aging2023$392,709September 15, 2023August 31, 2024WANG, CUN-YUreporter.nih.gov
Deep learning for opportunistic screening for osteoporosis and osteopenia from radiographsNIHNational Institute of Biomedical Imaging and Bioengineering2024$391,669March 13, 2024December 5, 2024SEBRO, RONNIEreporter.nih.gov
Comprehensive assessment of bone quality using clinical photon-counting detector CTNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024$391,588September 20, 2024August 31, 2026RAJENDRAN, KISHOREreporter.nih.gov
Skeletal Health and Bone Marrow Composition in Adolescents with Crohn’s DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2024$391,380August 4, 2023May 31, 2027GORDON, REBECCA JUDITHreporter.nih.gov
RAMP-altered class B GPCR hormone binding and signalingNIHNational Institute of General Medical Sciences2025$389,310September 1, 2025July 31, 2030PIOSZAK, AUGEN Areporter.nih.gov
Impact of estrogen replacement therapy on bone health in an aging population of women living with HIVNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$387,804August 6, 2024July 31, 2027SAUTER, KRISTIN ADreporter.nih.gov
Bone Health in Adults with Type 1 DiabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024$384,129September 13, 2019August 31, 2025SHAH, VIRAL Nreporter.nih.gov
Behavioral, Lifestyle, and Cultural Risk Factors for Bone Quality and Osteoporosis in the PROSPECT CohortNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$382,896January 1, 2025December 31, 2028NOEL, SABRINAreporter.nih.gov
Mechanistic Determinants of Dietary Polyphenol Bioactivity in BoneNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$382,574June 21, 2021May 31, 2024FUNK, JANET Lreporter.nih.gov
Investigating the Impact of Social Isolation on Bone MetabolismNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$382,281July 1, 2023June 30, 2028MOUNTAIN, REBECCAreporter.nih.gov
The role of Tmem263 in regulation of bone mass and strengthNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$381,827May 5, 2021April 30, 2024ECONS, MICHAEL Jreporter.nih.gov
Genetic Factors of Bone Loss in Older Adults Taking AntidepressantsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$381,270September 1, 2018June 30, 2022PETERSON, TIMOTHY Rreporter.nih.gov
FAT TALKS TO BONENIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$381,250July 11, 2017June 30, 2023TEITELBAUM, STEVEN Lreporter.nih.gov
Novel Molecular and Cellular Mechanisms for Osteoanabolic Action of Parathyroid HormoneNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$380,579April 1, 2019March 31, 2023WANG, BINreporter.nih.gov
Pathogenesis of LRP6 High Bone MassNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$379,418July 6, 2021June 30, 2025MUMM, STEVEN Rreporter.nih.gov
Bone-Adipose Interactions During Skeletal AnabolismNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$377,865April 1, 2021June 30, 2022RIDDLE, RYAN Creporter.nih.gov
Vesicle Trafficking and Osteoblast FunctionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2023$377,584September 23, 2022July 31, 2024WU, JOY Yreporter.nih.gov
Non-Invasive Determination of Bone Quality Markers by Monte Carlo Modeling and Optical SpectroscopyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2023$377,434July 1, 2022June 30, 2025PLESHKO, NANCYreporter.nih.gov
Rdh10 and retinoic acid effects on differentiationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$376,134September 18, 2017July 31, 2023NAPOLI, JOSEPH Lreporter.nih.gov
Cellular Mechanisms of Age-Associated Cortical Bone RemodelingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024$375,100September 20, 2024August 31, 2026BRADLEY, ELIZABETH Wreporter.nih.gov
Improved Treatment of Vertebral Compression Fractures for Elderly Patients Using an Image-Guided, Percutaneous Delivery of a Novel Bone AdhesiveNIHNational Institute on Aging2022$375,000August 15, 2022July 31, 2023HESS, BRIANreporter.nih.gov
Mitochondrial genetics as a determinant of bone healthNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2023$372,680September 20, 2022August 31, 2025ELISEEV, ROMANreporter.nih.gov
Hyponatremia-Induced Osteoporosis and FragilityNIHNational Institute on Aging2021$372,181July 1, 2017May 31, 2023VERBALIS, JOSEPH Greporter.nih.gov
The STING pathway and cytosolic nucleic acid sensors in bone homeostasisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$357,867July 19, 2017May 31, 2022GRAVALLESE, ELLEN Mreporter.nih.gov
PTH (1-34) and pelvic fracture healing: A randomized controlled trialNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$356,297May 23, 2019March 31, 2024NIEVES, JERI WANZORreporter.nih.gov
Lrp5 and Lrp6 signaling in bone mechanotransduction and metabolismNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023$348,748September 18, 2023August 31, 2024ROBLING, ALEXANDER Greporter.nih.gov
Muscle and Bone Growth in AgingNIHNational Institute on Aging2022 to 2025$347,913September 15, 2021August 31, 2026KOK, HUI JEANreporter.nih.gov
Etiology and Prevention of Loss of Fixation in Cemented Knee ReplacementsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$345,708July 15, 1996July 31, 2023MANN, KENNETH A.reporter.nih.gov
Reducing Post-Radiotherapy Bone Fragility Through Orchestrated Cell SurvivalNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$345,708August 1, 2017July 31, 2024OEST, MEGAN ELIZABETHreporter.nih.gov
Determining the Role of Brain-Derived CCN3 in Bone and Marrow Fat MetabolismNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$342,996July 15, 2024March 31, 2029BABEY, MURIELreporter.nih.gov
Mechanisms of Systemic Bone Loss Following Femur Fracture in MiceNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$342,900September 1, 2017July 31, 2023CHRISTIANSEN, BLAINE A.reporter.nih.gov
Marrow adipocytes modify the neural regulation of boneNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022$341,011September 22, 2022August 31, 2024SCHELLER, ERICA LYNNreporter.nih.gov
Heparan Sulfate–Osteoprotegerin Interactions in Bone RemodelingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$338,869August 1, 2017May 31, 2023XU, DINGreporter.nih.gov
Identification of osteoclast endocrine and paracrine communications by systems genetics approachesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023$338,508September 20, 2023August 31, 2025ZHAO, HAIBOreporter.nih.gov
Primary Cilia as Mechanotransducer in BoneNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$335,274August 1, 2012May 31, 2023GUO, X. EDWARDreporter.nih.gov
A new model for spatio-temporal coupling of bone formation and bone resorption governed by osteoclastsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$334,845September 1, 2020August 31, 2023MISHINA, YUJIreporter.nih.gov
Volumetric bone density, geometry, strength and bone tissue material properties in type 1 diabetesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$333,884April 10, 2019March 31, 2024SHAH, VIRAL Nreporter.nih.gov
Veverimer to decrease net acid excretion and bone resorption in adults with osteopenia: a dose-finding randomized controlled trialNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$331,051August 10, 2025July 31, 2028CEGLIA, LISAreporter.nih.gov
Effects of reproduction and lactation on postmenopausal bone health.NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$330,820July 1, 2017April 30, 2023LIU, XIAOWEI SHERRYreporter.nih.gov
Characterizing the mechanism by which endogenous negative regulators of osteoclasts control bone homeostasis under physiological and pathological conditions in mouse modelsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$324,368April 1, 2017March 31, 2024CHEN, WEIreporter.nih.gov
Characterizing neurocognitive symptoms in older adults with primary hyperparathyroidismNIHNational Institute on Aging2023$322,000August 15, 2023August 14, 2025KAZAURE, HADIZA Sreporter.nih.gov
Skeletal Consequences of Mild Autonomous Cortisol SecretionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$314,224August 19, 2019May 31, 2023BANCOS, IRINAreporter.nih.gov
Bone anabolic effects of osteoclast-produced phospho-Wnt5aNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023$313,000September 18, 2023August 31, 2025DRISSI, MOULAY HICHAMreporter.nih.gov
Predicting who will fracture: Exploration of machine learning in the observational Women's Health Initiative Study dataset.NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2023$309,862September 21, 2022August 31, 2025CRANDALL, CAROLYN JANETreporter.nih.gov
Functions of the PH-Domain Leucine Rich Protein Phosphatase (Phlpp)1 in OsteoclastsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$309,097September 21, 2017July 31, 2023BRADLEY, ELIZABETH Wreporter.nih.gov
Elucidating the Role of TGF-Beta Signaling in Craniofacial Fibrous Dysplasia of the BoneNIHNational Institute of Dental & Craniofacial Research2024$306,600September 24, 2024September 23, 2026WENTWORTH, KELLY LEEreporter.nih.gov
Influence of aging on the preB cell product, λ5, and its contribution to age-related bone lossNIHNational Institute on Aging2022$304,425July 1, 2022June 30, 2025KHASS, MOHAMEDreporter.nih.gov
Estrogen receptor reprogramming ligands for the prevention of protracted menopausal symptoms and chronic diseasesNIHNational Institute on Aging2023$298,883September 1, 2023August 31, 2024LEITMAN, DALE Creporter.nih.gov
Multifactorial contribution of bone nanoscale composition to tissue quality in osteoporosisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2024$297,182December 1, 2023June 30, 2024QUERIDO, WILLIAMreporter.nih.gov
AutoChamber: an FDA-Designated Breakthrough AI Add-on to Coronary Artery Calcium and Lung Cancer Screening CT Scans to Flag Patients at High Risk of Atrial Fibrillation, Stroke and Heart FailureNIHNational Heart, Lung, and Blood Institute2024$294,023September 27, 2024September 26, 2025NAGHAVI, MORTEZAreporter.nih.gov
Direct and indirect contributions of perivascular stem cells to bone healingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$275,925August 28, 2017June 30, 2023JAMES, AARON Wreporter.nih.gov
Application of precision medicine to phototherapy: a stepped care approach to consolidate sleep and slow cognitive decline in older adultsNIHNational Institute on Aging2024 to 2025$262,170August 9, 2024December 31, 2025LOK, RENSKEreporter.nih.gov
Discovery of osteoblast and osteoclast bone mass effector genes using advanced genomicsNIHNational Institute on Aging2021$256,985September 30, 2021July 31, 2022HANKENSON, KURT DAVIDreporter.nih.gov
Development of reprogramming ligands for menopausal hormone therapyNIHNational Institute on Aging2021$255,543September 1, 2021August 31, 2022LEITMAN, DALE Creporter.nih.gov
Demystify Heparan Sulfate–Sclerostin Interactions in Bone FormationNIHNational Institute of Dental & Craniofacial Research2023 to 2024$254,934February 1, 2023July 31, 2024LI, MIAOMIAOreporter.nih.gov
The Role of Irisin in Initiating Resorption During the Skeletal Response to ExerciseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2024$254,854February 1, 2023January 31, 2025ESTELL, EBEN GRANTreporter.nih.gov
High Performance Computer for Biomedical ResearchNIHOffice of the Director, National Institutes of Health2022$249,919June 1, 2022May 31, 2025PARISH, CAROL Areporter.nih.gov
Optimizing Small Molecule Mechanomimetics to Treat Age-related Osteoporosis.NIHNational Institute on Aging2023$249,658September 30, 2023August 31, 2025QUARLES, L DARRYLreporter.nih.gov
Fibrinogen coated albumin spheres to accelerate bone healing in older adults.NIHNational Institute on Aging2021$246,634September 30, 2021May 31, 2023YEN, RICHARDreporter.nih.gov
FAS Controls Exosome-Mediated miRNA Transfer in MSC-Based TherapyNIHNational Institute of Dental & Craniofacial Research2021$240,032April 3, 2019March 31, 2023CHEN, CHI-DERreporter.nih.gov
Early Life Phthalate and Perfluoroalkyl Substance Exposures and Childhood Bone HealthNIHNational Institute of Environmental Health Sciences2023$238,560July 1, 2023November 30, 2025BUCKLEY, JESSIE Preporter.nih.gov
Osteocyte CaMKII as a Critical Regulator of Bone Physiology AnabolismNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024$230,089March 21, 2018June 15, 2025STAINS, JOSEPH P.reporter.nih.gov
Osteocyte peri-lacunar/canalicular remodeling in maternal bone adaptationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024$228,125July 1, 2017June 30, 2026LIU, XIAOWEI SHERRYreporter.nih.gov
Reversing Skeletal Aging by Restoring Functional Skeletal Stem Cell DiversityNIHNational Institute on Aging2021 to 2022$227,392April 1, 2021December 31, 2022AMBROSI, THOMAS HANSreporter.nih.gov
Effects of semaglutide on bone and muscle endpoints in adults with obesity: a pilot study.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2023$224,528January 1, 2022December 31, 2024HAINES, MELANIE SCHORRreporter.nih.gov
The role of GGPS1 and CYP1A1 mutations in atypical femoral fractureNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$220,850August 1, 2020July 31, 2024BARON, ROLAND Ereporter.nih.gov
Using In Vitro Culture to Detect Changes in Bone Matrix Mechanical PropertiesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$219,609September 5, 2025August 31, 2027HERNANDEZ, CHRISTOPHER JOHNreporter.nih.gov
Acquisition of a Verasonics Vantage 256 Research Ultrasound PlatformNIHOffice of the Director, National Institutes of Health2022$218,000August 15, 2022August 14, 2023CARDOSO, LUISreporter.nih.gov
Sclerostin Regulation of Skeletal Mineralization and Phosphate MetabolismNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$211,844September 1, 2019August 31, 2023ROSS, RYAN DEEreporter.nih.gov
Girk3 in bone biology and diseaseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2024$209,734May 1, 2023September 3, 2024WEAVER, SAMANTHA Rreporter.nih.gov
The epigenetic role of LSD1 in osteoclast differentiationNIHNational Institute of Dental & Craniofacial Research2021 to 2024$204,112August 29, 2020August 28, 2025ASTLEFORD-HOPPER, KRISTINAreporter.nih.gov
Bone Metabolism in Adolescents UndergoingBariatric SurgeryNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$202,437April 1, 2017September 30, 2023BREDELLA, MIRIAM ANTOINETTEreporter.nih.gov
Functional domains of bone sialoprotein in dentoalveolar development and healingNIHNational Institute of Dental & Craniofacial Research2021 to 2024$197,956August 1, 2021July 31, 2025CHAVEZ, MICHAEL B.reporter.nih.gov
Skeletal Health and Bone Marrow Composition in Adolescents with Crohn's DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$197,640August 4, 2023May 31, 2027GORDON, REBECCA JUDITHreporter.nih.gov
Regulation of Gastric and Osteoclat Acidification by Snx10NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$196,949September 1, 2021March 31, 2022BATTAGLINO, RICARDO ANIBALreporter.nih.gov
Modifying fragility fracture healing using a gradient-based mechanotransduction fixation approachNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$196,323March 1, 2025May 31, 2027HAST, MICHAEL WILLIAMreporter.nih.gov
Urea for chronic hyponatremia: a pilot studyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$195,625August 11, 2020May 31, 2023RONDON BERRIOS, HELBERTreporter.nih.gov
Influence of the gut microbiome on normal and senile fracture healingNIHNational Institute on Aging2021$191,280January 1, 2020November 30, 2022DRISSI, MOULAY HICHAMreporter.nih.gov
Characterization of sodium dependent phosphate transporter 2 signaling in hard tissue mineralizationNIHNational Institute of Dental & Craniofacial Research2021 to 2024$191,056July 1, 2019June 30, 2025WALCZAK, PHILIP ADAMreporter.nih.gov
Targeting cellular senescence with senolytics to improve skeletal health in older humansNIHNational Institute on Aging2021$189,645February 15, 2020January 31, 2023FARR, JOSHUA NICHOLASreporter.nih.gov
Building a Collaborative Research and TrainingPlatform for HIV and Rheumatic and Musculoskeletal Diseases in UgandaNIHFogarty International Center2025$187,169July 21, 2025June 30, 2027KADDUMUKASA, MARKreporter.nih.gov
Aza-Heck/C-C cleavage/cross coupling cascades of pinene derivatives for the synthesis of zoanthamine alkaloidsNIHNational Institute of General Medical Sciences2021 to 2023$185,572January 1, 2021September 15, 2023NA, CHRISTINA GRACEreporter.nih.gov
Thyroid hormone receptor β1 agonist therapy for the treatment of bone marrow adiposity in aging and obesityNIHNational Institute on Aging2021$183,125March 15, 2020December 31, 2023MOHAN, SUBBURAMANreporter.nih.gov
Appraising the Fracture Risk Assessment Tool (FRAX) in persons with rheumatoid arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$177,120September 1, 2025August 31, 2030ELAM, RACHEL ELIZABETHreporter.nih.gov
Metabolomic & Radiographic Markers of Fracture Risk Among Older Adults with DiabetesNIHNational Institute on Aging2021 to 2022$176,371April 15, 2018January 31, 2023LEE, RICHARD HSANG-YANGreporter.nih.gov
Genetic Modifiers and Diagnostics for Bone Health in Cystic FibrosisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$176,040September 1, 2025August 31, 2030WU, MALINDAreporter.nih.gov
Cross Talk of Mechanical and Hormonal Signals to Increase Bone MassNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$175,948June 1, 2025May 31, 2030PAPAIOANNOU, GARYFALLIAreporter.nih.gov
Building a Collaborative Research and Training Platform for HIV and Rheumatic and Musculoskeletal Diseases in UgandaNIHFogarty International Center2024$174,753August 19, 2024June 30, 2026HSIEH, EVELYNreporter.nih.gov
Age Differences and Mechanisms of Ketogenic Diet Induced Bone LossNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2024$171,836August 1, 2023July 31, 2025OSIPOV, BENJAMINreporter.nih.gov
Determining the Role of Plastin-3 in Osteoblast Differentiation and MineralizationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$171,324September 1, 2021August 31, 2025CHIN, SAMANTHA MEAGANreporter.nih.gov
Mechanisms and impact of osteoblast "citration" on skeletal mineralization and global citrate homeostasisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2023$170,860September 1, 2022January 31, 2024DIRCKX, NAOMIreporter.nih.gov
Biasing OGR1 signaling to optimizing PTH therapeutic effectNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$166,452February 1, 2020July 31, 2022WANG, BINreporter.nih.gov
Investigating the Perturbation of Bone Health by Per/Polyfluoroalkyl SubstancesNIHNational Institute of Environmental Health Sciences2023 to 2024$165,000December 1, 2022November 30, 2025SCHLEZINGER, JENNIFER Jreporter.nih.gov
Fracture Risk Prediction After Age 80 YearsNIHNational Institute on Aging2021$164,988September 30, 2020May 31, 2024ENSRUD, KRISTINEreporter.nih.gov
Spatial correlation of osteocyte gene response to local mechanical strain in bone tissueNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$164,851April 1, 2020March 31, 2023NIEBUR, GLEN Lreporter.nih.gov
Impact of Different Classes of Osteoporosis Medications on Muscle Health in Older AdultsNIHNational Institute on Aging2025$162,020August 5, 2025July 31, 2030SAFAI HAERI, NAMIreporter.nih.gov
URBAN ARCH (5/5) Boston Cohort - Alcohol and HIV-associated comorbidity and complications: Frailty, Functional impairment, Falls, and Fractures (the 4F study)NIHNational Institute on Alcohol Abuse and Alcoholism2021$161,316September 20, 2011August 31, 2023HEEREN, TIMOTHY C.reporter.nih.gov
Nuclear Events in PTHR1 Action on BoneNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$158,500December 1, 1994April 30, 2022PARTRIDGE, NICOLA Creporter.nih.gov
The role of cellular senescence in bone loss and recovery in periodontal diseaseNIHNational Institute of Dental & Craniofacial Research2023$158,500July 1, 2023January 31, 2024KITTAKA, MIZUHOreporter.nih.gov
Dissecting the Molecular Mechanisms that Govern Notch Mediated Skeletal Stem Cell Maintenance Throughout Adulthood/Aging.NIHNational Institute on Aging2022 to 2024$158,420February 28, 2022February 27, 2026REMARK, LINDSEY HOPEreporter.nih.gov
Identifying the long-term metabolic complications of in-utero and lactational antiretroviral exposureNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023$158,000September 6, 2023August 31, 2025ROSS, RYAN DEEreporter.nih.gov
The role of osteocytes in alcohol-induced osteopeniaNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2023$157,199June 1, 2021May 31, 2024DENYS, ALEXANDRAreporter.nih.gov
Critical Role of the Gut Microbiota in Prunes’ Prevention of Glucocorticoid Induced OsteoporosisNIHNational Center for Complementary & Integrative Health2023 to 2025$157,195July 6, 2023July 5, 2028CHARGO, NICHOLASreporter.nih.gov
Development and Validation of an Image Based, Computed Trabecular Network Model for Estimating Vertebral Fracture Risk in the Aging PopulationNIHNational Institute on Aging2021 to 2023$155,482April 1, 2019March 31, 2024MOORE, AUSTIN MARKreporter.nih.gov
The Effect of Etelcalcetide on Bone-tissue Properties in End Stage Kidney DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$155,482June 1, 2019May 31, 2024DAMRATH, JOHNreporter.nih.gov
The role of cellular senescence in bone loss and recovery in periodontal diseaseNIHNational Institute of Dental & Craniofacial Research2024$154,000July 1, 2024June 30, 2026KITTAKA, MIZUHOreporter.nih.gov
Mechanistic association of epigenetic bone age and frailty measures with bone imaging studies using novel artificial intelligence approachesNIHNational Institute on Aging2025$149,889September 1, 2025May 31, 2030VAN SCHAIK, KATHERINE DOUGLASreporter.nih.gov
Effects of alcohol on bone remodeling balance in male and female non-human primates and humansNIHNational Institute on Alcohol Abuse and Alcoholism2024 to 2025$148,500September 17, 2024August 31, 2026IWANIEC, URSZULA Treporter.nih.gov
Shape Memory Polymer Scaffolds to Treat Bone Defects in Patients with Alzheimer's DiseaseNIHNational Institute on Aging2021$145,412September 15, 2020June 30, 2023HAHN, MARIAH Sreporter.nih.gov
Does aging decrease osteocyte lacunar-canalicular bone quality?NIHNational Institute on Aging2021 to 2022$144,000April 1, 2021January 31, 2024HEVERAN, CHELSEA MARIEreporter.nih.gov
Prebiotic Activity of Tart Cherry and the Immunoregulation of Bone HomeostasisNIHNational Center for Complementary & Integrative Health2021$142,200September 1, 2020August 31, 2023CLARKE, STEPHEN Lreporter.nih.gov
Exercise for Sarcopenia in Allogeneic Hematopoietic Stem Cell Transplant PatientsNIHNational Cancer Institute2021 to 2022$140,692June 1, 2020May 31, 2023POTIAUMPAI, MELANIEreporter.nih.gov
Multi-omic dissection of clonal hematopoiesis-associated diseasesNIHNational Human Genome Research Institute2023$136,890September 15, 2023September 14, 2024YU, ZHIreporter.nih.gov
Exploring genomic determinants of periodontal disease via shared genetic pathways with cardiovascular disease, diabetes, and bone densityNIHNational Institute of Dental & Craniofacial Research2021$136,629September 13, 2017December 31, 2022YU, YAU-HUAreporter.nih.gov
Effect of a ghrelin receptor agonist on muscle and boneNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022$131,551April 10, 2019February 29, 2024DAWSON-HUGHES, BESSreporter.nih.gov
NMUR2 in bone formationNIHNational Institute on Aging2024$130,600May 15, 2024April 30, 2026LOWERY, JONATHAN WAYNEreporter.nih.gov
Unraveling Mechanisms Driving Female-Specific Osteogenesis after Disrupting a Brain-to-Bone CircuitNIHNational Institute on Aging2021$130,424May 1, 2020January 28, 2022HERBER, CANDICEreporter.nih.gov
Gut microbial factors that increase bone tissue strengthNIHNational Institute on Aging2022 to 2023$127,124September 1, 2022July 1, 2024CYPHERT, ERIKA LEAHreporter.nih.gov
The Role of Irisin in Initiating Resorption During the Skeletal Response to ExerciseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$126,900February 1, 2025January 31, 2028ESTELL, EBEN GRANTreporter.nih.gov
Linking GWAS variants to function with single-cell pooled CRISPR screensNIHNational Human Genome Research Institute2023 to 2024$123,206February 16, 2023March 29, 2024MORRIS, JOHN ALLANreporter.nih.gov
The Myokine Irisin Modulates Bone Resorption via Stimulation of OsteoclastogenesisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$122,352May 5, 2020January 31, 2023ESTELL, EBEN GRANTreporter.nih.gov
Impacts of SARS-CoV-2 Infection and Age on Musculoskeletal HealthNIHNational Institute on Aging2022 to 2024$120,928September 1, 2022August 31, 2025AWOSANYA, OLATUNDUN DUPEreporter.nih.gov
Establishing the role of genetic variation in vitamin D-regulated gene expression in Sjogrens disease pathogenesisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$120,908August 30, 2022August 29, 2025YILMAZ, DEFNEreporter.nih.gov
: Osteoporosis and Sarcopenia in COPD and CT-based PhenotypesNIHNational Heart, Lung, and Blood Institute2025$116,625February 1, 2025January 31, 2027SAHA, PRANAV K.reporter.nih.gov
Developing a Novel Vascularized Bone Microdevice for Investigating the Post-Stroke Bone MicroenvironmentNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$114,749July 1, 2022May 31, 2025STANGELAND-MOLO, SANDRA JEANNEreporter.nih.gov
ASBMR Three Year Pre-Meeting SymposiaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$113,000June 1, 2022May 31, 2025BELLIDO, TERESITA M.reporter.nih.gov
Bone health assessment through magnetic susceptibility mappingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$112,106December 1, 2021February 27, 2024JONES, BRANDON CLINTONreporter.nih.gov
Design of Phosphonate-based Coordination Polymers as Targeted MultidrugDelivery Systems for Bone TherapyNIHNational Institute of General Medical Sciences2021$111,750April 1, 2020December 31, 2021LOPEZ-MEJIAS, VILMALIreporter.nih.gov
The Role of Bone Sialoprotein in Modulating Periodontal Development and RepairNIHNational Institute of Dental & Craniofacial Research2023 to 2024$108,268August 1, 2023December 1, 2025ANDRAS, NATALIE LYNNreporter.nih.gov
In vivo Osteocyte Ca2+ Signaling in Aging BoneNIHNational Institute on Aging2021 to 2023$103,546May 1, 2021April 30, 2024BOORMAN-PADGETT, JAMESreporter.nih.gov
The impact of dysbiosis and the IL-12/23 signaling axis on IBD-associated bone loss.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$99,030February 1, 2019January 31, 2023PEEK, CHRISTOPHER THOMASreporter.nih.gov
INVESTigations of Muscle and Bone Health: Developing Automated Approaches for CT-Based AnalysesNIHNational Institute on Aging2024 to 2025$98,512June 12, 2024June 11, 2027LYNCH, DELANIEreporter.nih.gov
Regulation of PTH-induced RankL transcription in osteoblastsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$92,788September 1, 2020August 31, 2023MOSCA, MICHAEL JOSEPHreporter.nih.gov
Developing an Automated Image Analysis and Finite Element Modeling Platform to Assess the Effects of Supplemental Protein and Weight Loss on Bone Health in Obese Older AdultsNIHNational Institute on Aging2021 to 2022$92,788August 20, 2020August 19, 2023GREENE, KATELYN ANNEreporter.nih.gov
Targeting multiple Wnt inhibitors for synergistic anabolic action in the skeletonNIHNational Institute on Aging2021 to 2023$90,652April 1, 2021July 31, 2023CHOI, ROY BYUNG-JUNreporter.nih.gov
RANKL regulation of human B cell responsesNIHNational Institute of Allergy and Infectious Diseases2025$88,360July 1, 2025June 30, 2026KOTZIN, JONATHAN Jreporter.nih.gov
Hip Fracture Prediction by Combining Fall Risk, Impact Loads and Bone StrengthNIHNational Institute on Aging2021$87,500June 15, 2020March 31, 2023JOHANNESDOTTIR, FJOLAreporter.nih.gov
High-Resolution Plasma Metabolomics to Determine Linkages between Estrogen-Induced Bone Loss and Intestinal Barrier Integrity in HIVNIHNational Institute on Aging2021$78,000January 1, 2020November 30, 2021ALVAREZ, JESSICA ALEJANDRAreporter.nih.gov
Enhancing B cell maturation and function using bisphosphonates in HIVNIHNational Heart, Lung, and Blood Institute2021$78,000August 15, 2020July 31, 2022TITANJI, KEHMIA NUBONYINreporter.nih.gov
Neuroskeletal crosstalk in load-induced bone formationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2023$76,039April 1, 2022May 22, 2023BEEVE, ALEC Treporter.nih.gov
Bone Turnover Responses to Sleep Restriction and Subsequent Sleep RecoveryNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$75,417March 1, 2020February 28, 2022SWANSON, CHRISTINE Mreporter.nih.gov
Follicle Stimulating Hormone and Bone Loss in Postmenopausal WomenNIHNational Institute on Aging2021 to 2022$55,612September 1, 2021December 30, 2022MATTICK, LINDSEY JEANreporter.nih.gov
Role of Hypoxia-inducible factor-2α signaling in age-induced bone lossNIHNational Institute on Aging2025$55,496December 15, 2024November 30, 2026MENDOZA, SARAH VANESSAreporter.nih.gov
Development and Validation of an Image Based, Computed Trabecular Network Model for Estimating Vertebral Fracture Risk in the Aging PopulationNIHNational Institute on Aging2024$53,974April 1, 2019March 31, 2025MOORE, AUSTIN MARKreporter.nih.gov
Regulation of Skeletal Development and Mechanosensitivity by the α2δ1 Auxiliary Voltage Sensitive Calcium Channel SubunitNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$51,422May 1, 2019January 31, 2022WRIGHT, CHRISTIAN STEPHENreporter.nih.gov
Restoring the Responsiveness of Aged Bone to Mechanical LoadingNIHNational Institute on Aging2021$51,036September 16, 2019September 15, 2022CHERMSIDE-SCABBO, CHRISTOPHER JOHNreporter.nih.gov
Investigating the Role of Sclerostin in Calcific Aortic Valve DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2022$50,428February 1, 2020March 31, 2022JOLL, JEFFERY Ereporter.nih.gov
Advances in Musculoskeletal & Neuronal InteractionsNIHNational Institute on Aging2022$50,000February 1, 2022January 31, 2023DRISSI, MOULAY HICHAMreporter.nih.gov
Muscle and Bone Growth in AgingNIHNational Institute on Aging2021$46,435September 15, 2021August 31, 2022KOK, HUI JEANreporter.nih.gov
Investigating the role of FGF21 in bone homeostasis in Duchenne Muscular DystrophyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$46,138May 1, 2025April 30, 2029HURLEY-NOVATNY, AMELIA CHARLOTTEreporter.nih.gov
Investigating miRNA-Mediated Bone Loss from Morphine TreatmentNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$44,119March 11, 2024May 10, 2025LANGLAIS-ELLIOTT, AUDRIEreporter.nih.gov
Adipsin from bone marrow fat as a regulator of bone remodelingNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$43,883September 1, 2020July 31, 2022AARON, NICOLEreporter.nih.gov
Eighteenth Forum on Osteoporosis and Metabolic Bone Diseases for Fellows in TrainingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2024$43,400July 1, 2023June 30, 2025BILEZIKIAN, JOHN Preporter.nih.gov
ASBMR Three Year SymposiaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$40,000April 1, 2019March 30, 2022CAULEY, JANE ANNreporter.nih.gov
Raman spectroscopy as a non-invasive, transcutaneous tool for characterizing bone healthNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022$37,968May 1, 2022December 30, 2022MASSIE, CHRISTINEreporter.nih.gov
Sympathetic signaling as a candidate mechanism underlying bone loss after spinal cord injuryNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$37,568June 1, 2025May 31, 2027BRYAN, JESSICAreporter.nih.gov
Modeling ovarian aging phenotype in mechanically tuned 3D matricesNIHNational Institute on Aging2021$35,227September 1, 2018May 31, 2022GARGUS, EMMAreporter.nih.gov
Mechanisms by Which Bone Marrow Adipose Tissue Expands During Calorie RestrictionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$34,281September 4, 2019March 3, 2022SCHILL, REBECCA L.reporter.nih.gov
The Role of Reactive Oxygen Species in Osteocyte Mechano-Transduction and Sclerostin RegulationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$34,236April 1, 2021March 31, 2023GOULD, NICOLE R.reporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Icahn School of Medicine at Mount SinaiNew York, NY5$32.2 million0$0
California Pacific Med CTR Res InstituteSan Francisco, CA2$25.4 million0$0
Mayo Clinic RochesterRochester, MN11$20.8 million0$0
MainehealthPortland, ME9$19.3 million0$0
Univ of Arkansas for Med ScisLittle Rock, AR7$18.8 million0$0
Augusta UniversityAugusta, GA5$18.6 million0$0
Johns Hopkins UniversityBaltimore, MD17$18.6 million0$0
University of California, San FranciscoSan Francisco, CA12$18.3 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA12$17.3 million0$0
Indiana University IndianapolisIndianapolis, IN18$15.8 million0$0
Columbia University Health SciencesNew York, NY16$15.1 million0$0
Tulane University of LouisianaNew Orleans, LA4$14.5 million0$0
Massachusetts General HospitalBoston, MA15$12.9 million0$0
University of PennsylvaniaPhiladelphia, PA15$12.9 million0$0
Brigham and Women's HospitalBoston, MA7$12.3 million0$0
University of Colorado DenverAurora, CO12$12.3 million0$0
University of Michigan at Ann ArborAnn Arbor, MI14$11.6 million0$0
Hebrew Rehabilitation Center for AgedBoston, MA7$11.2 million0$0
Emory UniversityAtlanta, GA11$10.3 million0$0
Ohio State UniversityColumbus, OH7$9.9 million0$0
Boise State UniversityBoise, ID2$9.6 million0$0
Wake Forest UniversityWinston Salem, NC3$9.2 million0$0
Stanford UniversityStanford, CA6$9.2 million0$0
University of RochesterRochester, NY6$8.8 million0$0
Wake Forest University Health SciencesWinston-Salem, NC9$8.6 million0$0
Wichita State UniversityWichita, KS1$8.5 million0$0
SUNY at BuffaloAmherst, NY5$8 million0$0
Vanderbilt University Medical CenterNashville, TN6$7.9 million0$0
University of California, San DiegoLa Jolla, CA4$7.6 million0$0
University of VirginiaCharlottesville, VA5$7.6 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA3$7.3 million0$0
University of California Los AngelesLos Angeles, CA8$7.2 million0$0
University of Alabama at BirminghamBirmingham, AL3$6.7 million0$0
Yale UniversityNew Haven, CT6$6.6 million0$0
Iq Solutions, Inc.Rockville, MD2$6.3 million0$0
Washington UniversitySaint Louis, MO10$6.2 million0$0
University of Tennessee Health Sci CTRMemphis, TN3$5.4 million0$0
Weill Medical Coll of Cornell UnivNew York, NY2$5.4 million0$0
Active Life Scientific, Inc.Santa Barbara, CA1$5.2 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX3$4.9 million0$0
Baylor College of MedicineHouston, TX4$4.7 million0$0
Revbio, Inc.Lowell, MA3$4.4 million0$0
Texas A&m Agrilife ResearchCollege Station, TX2$4.4 million0$0
University of Connecticut SCH of Med/dntFarmington, CT5$4.3 million0$0
University of Kansas Medical CenterKansas City, KS1$4.1 million0$0
University of KentuckyLexington, KY2$4.1 million0$0
Osteodx Inc.Athens, OH1$4 million0$0
Hospital for Special SurgeryNew York, NY5$4 million0$0
Biosensics, LLCNewton, MA2$3.9 million0$0
SUNY at Stony BrookStony Brook, NY1$3.8 million0$0
Ut Southwestern Medical CenterDallas, TX3$3.7 million0$0
University of WashingtonSeattle, WA3$3.7 million0$0
University of California at DavisDavis, CA6$3.7 million0$0
University of Wisconsin-MadisonMadison, WI4$3.4 million0$0
University of Toledo Health Sci CampusToledo, OH2$3.4 million0$0
Loma Linda Veterans Assn Research & EducRedlands, CA4$3.4 million0$0
Boyce Thompson Institute Plant ResearchIthaca, NY1$3.2 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC5$3.1 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA3$2.9 million0$0
University of IowaIowa City, IA4$2.9 million0$0
University of MinnesotaMinneapolis, MN6$2.9 million0$0
University of Oklahoma HLTH Sciences CTROklahoma City, OK3$2.8 million0$0
Tufts University BostonBoston, MA3$2.8 million0$0
Boston Children's HospitalBoston, MA2$2.8 million0$0
University of Maryland BaltimoreBaltimore, MD5$2.8 million0$0
Kaiser Foundation Research InstituteOakland, CA1$2.8 million0$0
Bone Health Technologies, Inc.Redwood City, CA1$2.7 million0$0
Thomas Jefferson UniversityPhiladelphia, PA4$2.7 million0$0
CUNY City CollegeNew York, NY4$2.6 million0$0
Brown UniversityProvidence, RI1$2.5 million0$0
Harvard Medical SchoolBoston, MA2$2.4 million0$0
Rush University Medical CenterChicago, IL5$2.4 million0$0
Northern California Institute/res/eduSan Francisco, CA2$2.3 million0$0
Biovinc, LLCSanta Barbara, CA1$2.3 million0$0
University of California-Santa CruzSanta Cruz, CA1$2.3 million0$0
Harvard Pilgrim Health Care, Inc.Canton, MA1$2.2 million0$0
Centre Hospitalier de L'universite de Montreal (university of Montreal Hospital)Montreal1$2.1 million0$0
University of Nebraska-LincolnLincoln, NE1$2.1 million0$0
New York UniversityNew York, NY3$2 million0$0
University of Massachusetts AmherstAmherst, MA1$2 million0$0
Michigan State UniversityEast Lansing, MI2$1.9 million0$0
New York University School of MedicineNew York, NY3$1.9 million0$0
Boston University Medical CampusBoston, MA3$1.9 million0$0
Albert Einstein College of MedicineBronx, NY2$1.9 million0$0
Virginia Commonwealth UniversityRichmond, VA2$1.8 million0$0
Trustees of Boston UniversityBoston, MA1$1.8 million0$0
University of Colorado at BoulderBoulder, CO1$1.7 million0$0
Cayman Chemical Company, Inc.Ann Arbor, MI1$1.7 million0$0
If, LLCStoughton, WI1$1.7 million0$0
Miami UniversityOxford, OH1$1.5 million0$0
Duke UniversityDurham, NC4$1.4 million0$0
Clarkson UniversityPotsdam, NY1$1.4 million0$0
Northeast Ohio Medical UniversityRootstown, OH1$1.4 million0$0
Cornell UniversityIthaca, NY2$1.4 million0$0
University of Missouri-Kansas CityKansas City, MO2$1.4 million0$0
University of Texas HLTH Science CenterSan Antonio, TX2$1.4 million0$0
University of Texas at San AntonioSan Antonio, TX1$1.4 million0$0
Osteocentric Technologies, Inc.Austin, TX1$1.3 million0$0
Henry Ford Health SystemDetroit, MI1$1.3 million0$0
Van Andel Research InstituteGrand Rapids, MI1$1.3 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025186$111,239,8830$0
2024236$126,605,5870$0
2023265$144,188,3820$0
2022284$140,443,8790$0
2021285$140,567,1880$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 5 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 2 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)PA-24-184NIHMay 8, 2027Not listedNotice number printed on 1 award here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185NIHMay 7, 2027Not listedNotice number printed on 1 award here
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required)PAR-24-279NIH93.846November 2, 2026Not listedSame assistance listing 93.846 as 209 awards here
Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed)PAR-24-280NIH93.846November 2, 2026Not listedSame assistance listing 93.846 as 209 awards here
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)RFA-AT-25-003NIH93.846November 23, 2026$375,000Same assistance listing 93.846 as 209 awards here
Restoring Joint Health and Function to Reduce Pain (RE-JOIN) 2.0RFA-AR-26-006NIH93.846December 1, 2026Not listedSame assistance listing 93.846 as 209 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.846December 4, 2026Not listedSame assistance listing 93.846 as 209 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)PAR-27-039NIH93.846January 5, 2027Not listedSame assistance listing 93.846 as 209 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)PAR-27-040NIH93.846January 5, 2027Not listedSame assistance listing 93.846 as 209 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.846January 7, 2027Not listedSame assistance listing 93.846 as 209 awards here
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)RFA-NS-25-023NIH93.846January 15, 2027$350,000Same assistance listing 93.846 as 209 awards here
Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)PAR-24-268NIH93.846January 27, 2027$500,000Same assistance listing 93.846 as 209 awards here
NIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)PAR-25-141NIH93.846March 4, 2027Not listedSame assistance listing 93.846 as 209 awards here
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin DiseasesPAR-27-109NIH93.846March 4, 2027$600,000Same assistance listing 93.846 as 209 awards here
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)PA-27-100NIH93.846April 5, 2027Not listedSame assistance listing 93.846 as 209 awards here
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)PA-27-102NIH93.846April 5, 2027Not listedSame assistance listing 93.846 as 209 awards here
Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional)PA-24-201NIH93.846April 18, 2027Not listedSame assistance listing 93.846 as 209 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)PA-24-175NIH93.846May 7, 2027Not listedSame assistance listing 93.846 as 209 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.