Data / Research funding / Orthopoxviruses

Orthopoxviruses: 36 NIH awards ($75.8M) to 29 organizations

Name: NIH and NSF awards on Orthopoxviruses
Creator: SpecStream
License: https://creativecommons.org/licenses/by/4.0/

36 NIH awards ($75.8M) in the NIH spending category Orthopoxviruses, to 29 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Topic: NIH spending category

Awards

36 awards in the window.

Award	Agency	Institute or division	Fiscal year	Amount in window	Start	End	Principal investigator	Source
Task V15: Development of Assays and Reagents for mpox Vaccines	NIH	National Institute of Allergy and Infectious Diseases	2021 to 2025	$28,751,383	September 1, 2022	April 30, 2026	RUDGE, THOMAS	reporter.nih.gov
B-CELL EPITOPE DISCOVERY AND MECHANISMS OF ANTIBODY PROTECTION	NIH	National Institute of Allergy and Infectious Diseases	2021 to 2024	$5,936,710	September 16, 2019	August 31, 2025	CROWE, JAMES E	reporter.nih.gov
Advancement of a poxvirus antiviral	NIH	National Institute of Allergy and Infectious Diseases	2021 to 2025	$5,192,454	March 12, 2020	August 31, 2029	CONNOR, JOHN H	reporter.nih.gov
Novel Translational Control Mechanisms in Host Range Restriction of Poxvirus	NIH	National Institute of Allergy and Infectious Diseases	2021 to 2025	$2,420,139	September 22, 2020	August 31, 2030	XIANG, YAN	reporter.nih.gov
Viral inhibition of cell death in host immune responses	NIH	National Institute of Allergy and Infectious Diseases	2021 to 2024	$2,337,050	June 22, 2020	May 31, 2025	MIAO, EDWARD A	reporter.nih.gov
Biomarker Identification, Viral Susceptibility and Management in S. aureus Colonized AD Patients	NIH	National Institute of Allergy and Infectious Diseases	2021 to 2025	$2,310,254	April 6, 2020	March 31, 2027	BECK, LISA ANN	reporter.nih.gov
Poxvirus manipulation of the host cell protein synthesis machinery	NIH	National Institute of Allergy and Infectious Diseases	2021 to 2025	$2,267,115	November 23, 2016	December 31, 2026	WALSH, DEREK	reporter.nih.gov
IL-27-producing B cells in the antibody response	NIH	National Institute of Allergy and Infectious Diseases	2021 to 2025	$2,209,265	February 2, 2021	January 31, 2027	XU, ZHENMING	reporter.nih.gov
Mechanisms of protective memory CD8 T-cell induction by mRNA-LNP vaccines	NIH	National Institute of Allergy and Infectious Diseases	2023 to 2025	$2,140,211	June 1, 2023	May 31, 2028	SIGAL, LUIS J	reporter.nih.gov
Monkeypox virus, Interferon, and Necroptosis	NIH	National Institute of Allergy and Infectious Diseases	2021 to 2024	$1,856,868	May 24, 2012	July 31, 2025	JACOBS, BERTRAM L.	reporter.nih.gov
Development of novel antivirals against mpox (monkeypox) virus	NIH	National Institute of Allergy and Infectious Diseases	2024 to 2025	$1,550,961	June 14, 2024	April 30, 2029	WANG, ZHENGQIANG	reporter.nih.gov
Discovery of Antivirals Targeting Mpox Virus	NIH	National Institute of Allergy and Infectious Diseases	2024 to 2025	$1,549,199	May 8, 2024	March 31, 2029	SARAFIANOS, STEFAN G	reporter.nih.gov
Vertical transmission, pregnancy outcomes and treatment of Mpox virus infection in a translational pregnant macaque model	NIH	National Institute of Allergy and Infectious Diseases	2024 to 2025	$1,487,989	February 19, 2024	December 31, 2028	MOHR, EMMA L	reporter.nih.gov
Molecular mechanisms and ramifications of horizontal gene transfer into poxviruses	NIH	National Institute of Allergy and Infectious Diseases	2021 to 2024	$1,483,958	February 18, 2020	January 31, 2026	ROTHENBURG, STEFAN	reporter.nih.gov
The B22 family of orthopoxvirus virulence factors: Investigating structure/function of these potent, multifaceted immunoevasins	NIH	National Institute of Allergy and Infectious Diseases	2024 to 2025	$1,462,194	February 6, 2024	December 31, 2028	EISENLOHR, LAURENCE CRANE	reporter.nih.gov
New mechanisms governing skin tissue residency memory T cells	NIH	National Institute of Arthritis and Musculoskeletal and Skin Diseases	2024 to 2025	$1,428,241	April 1, 2024	March 31, 2029	ANANDASABAPATHY, NIROSHANA	reporter.nih.gov
Subversion of Cellular Mitotic and Antiviral Signaling by Poxviral Kinases	NIH	National Institute of Allergy and Infectious Diseases	2023 to 2025	$1,331,244	December 3, 2022	November 30, 2027	WIEBE, MATTHEW S	reporter.nih.gov
The role of mTOR dysregulation in poxvirus infection	NIH	National Institute of Allergy and Infectious Diseases	2024 to 2025	$1,315,135	November 17, 2023	October 31, 2028	WALSH, DEREK	reporter.nih.gov
TASK ORDER B03: EVALUATION OF ANTIVIRAL DRUG CANDIDATES AGAINST MPOX IN NHPS	NIH	National Institute of Allergy and Infectious Diseases	2024 to 2025	$1,258,076	September 30, 2025	September 29, 2026	SIVKO, GLORIA	reporter.nih.gov
Gigapixel Next-Generation-Sequencing: An Ultra-Sensitive Diagnostic for Infections of the CNS	NIH	National Institute of Allergy and Infectious Diseases	2024 to 2025	$1,221,032	November 1, 2023	October 31, 2027	ABATE, ADAM R.	reporter.nih.gov
Understanding the Function of F13 as a Matrix Protein for Poxvirus Intracellular Envelopment	NIH	National Institute of Allergy and Infectious Diseases	2023 to 2025	$1,143,450	February 10, 2023	January 31, 2027	WARD, BRIAN M	reporter.nih.gov
Defining Ocular Monkey Pox Pathogenic Mechanisms	NIH	National Eye Institute	2025	$713,991	July 1, 2025	June 30, 2030	ARUMUGASWAMI, VAITHILINGARAJA	reporter.nih.gov
Discovery of antiviral inhibitors for the treatment of orthopoxvirus infections	NIH	National Institute of Allergy and Infectious Diseases	2023 to 2024	$600,000	July 24, 2023	December 31, 2025	COBURN, GLEN	reporter.nih.gov
Microneedle patch delivery of replication-inducible monkeypox vaccine	NIH	National Institute of Allergy and Infectious Diseases	2025	$547,988	August 11, 2025	July 31, 2030	GAMBOTTO, ANDREA	reporter.nih.gov
Emerging and Re-Emerging Pathogens Research Training Program in DRC (EREP-RTP-DRC)	NIH	Fogarty International Center	2024 to 2025	$495,039	June 1, 2024	May 31, 2029	MUYEMBE-TAMFUM, JEAN-JACQUES TAMFUM	reporter.nih.gov
Decoding the Molecular and Antigenic Interactions in Orthopox Virus Entry	NIH	National Institute of Allergy and Infectious Diseases	2025	$466,125	August 1, 2025	July 31, 2027	DUERR, RALF	reporter.nih.gov
Comprehensive genetic dissection of poxvirus membrane assembly and function	NIH	National Institute of Allergy and Infectious Diseases	2023 to 2024	$462,000	December 1, 2022	November 30, 2025	CHANDRAN, KARTIK	reporter.nih.gov
Safer, More Effective Mpox/Smallpox Vaccine	NIH	National Institute of Allergy and Infectious Diseases	2025	$431,750	August 1, 2025	July 31, 2027	JACOBS, BERTRAM L.	reporter.nih.gov
Genomic Surveillance of Mpox through the Development of a Wastewater Intelligence Model and Data Analytics Platform	NIH	National Institute of Allergy and Infectious Diseases	2025	$416,625	August 7, 2025	July 31, 2027	OH, EDWIN C.	reporter.nih.gov
Poxvirus-encoded noncanonical open reading frames	NIH	National Institute of Allergy and Infectious Diseases	2023 to 2024	$404,584	May 5, 2023	April 30, 2026	YANG, ZHILONG	reporter.nih.gov
APOBEC3-driven host mechanism promotes poxvirus diversification to overcome host immune restriction	NIH	National Institute of Allergy and Infectious Diseases	2025	$221,105	May 1, 2025	April 30, 2027	LIU, JIA	reporter.nih.gov
Establishing Human 2D and 3D Testicular Models to Elucidate Monkeypox Virus Tropism and Pathogenic Mechanisms in the Testes	NIH	National Institute of Allergy and Infectious Diseases	2025	$156,500	August 1, 2025	July 31, 2027	VERMA, SAGUNA	reporter.nih.gov
Antiviral Resistance to Acyclic Phosphonates in Orthopoxviruses	NIH	National Institute of Allergy and Infectious Diseases	2025	$80,224	September 11, 2025	September 10, 2028	LEE, JASPER	reporter.nih.gov
Epidemiological factors related to human monkeypox virus (MPOX) in men who have sex with men (MSM) in the United States	NIH	National Institute of Allergy and Infectious Diseases	2024	$48,974	June 1, 2024	March 10, 2025	CARPINO, THOMAS	reporter.nih.gov
Characterization of a sensor domain for cytoplasmic nucleic acid in the antiviral factor, SAMD9	NIH	National Institute of Allergy and Infectious Diseases	2024	$38,314	September 1, 2024	August 31, 2025	MORALES, MARISOL	reporter.nih.gov
Uncovering the molecular underpinnings of C15, a potent orthopoxvirus virulence factor	NIH	National Institute of Allergy and Infectious Diseases	2024	$36,803	August 1, 2024	July 31, 2025	CARRO, STEPHEN DAVID	reporter.nih.gov

Organizations

Organization	Place	NIH awards	NIH amount	NSF amount
Battelle Memorial Institute	Columbus, OH	2	$30 million	$0
Vanderbilt University Medical Center	Nashville, TN	1	$5.9 million	$0
Boston University Medical Campus	Boston, MA	1	$5.2 million	$0
University of Texas HLTH Science Center	San Antonio, TX	3	$4.7 million	$0
Northwestern University at Chicago	Chicago, IL	2	$3.6 million	$0
University of Rochester	Rochester, NY	2	$3.5 million	$0
Duke University	Durham, NC	1	$2.3 million	$0
Arizona State University	Scottsdale, AZ	2	$2.3 million	$0
Thomas Jefferson University	Philadelphia, PA	1	$2.1 million	$0
Emory University	Atlanta, GA	2	$1.6 million	$0
University of Minnesota	Minneapolis, MN	1	$1.6 million	$0
University of Wisconsin-Madison	Madison, WI	1	$1.5 million	$0
University of California at Davis	Davis, CA	1	$1.5 million	$0
Children's Hosp of Philadelphia	Philadelphia, PA	1	$1.5 million	$0
Weill Medical Coll of Cornell Univ	New York, NY	1	$1.4 million	$0
University of Nebraska-Lincoln	Lincoln, NE	1	$1.3 million	$0
University of California, San Francisco	San Francisco, CA	1	$1.2 million	$0
University of California Los Angeles	Los Angeles, CA	1	$713,991	$0
Venatorx Pharmaceuticals, Inc.	Malvern, PA	1	$600,000	$0
University of Pittsburgh at Pittsburgh	Pittsburgh, PA	1	$547,988	$0
Institut National de Recherche Biomedical	Kinshasa	1	$495,039	$0
New York University School of Medicine	New York, NY	1	$466,125	$0
Albert Einstein College of Medicine	Bronx, NY	1	$462,000	$0
University of Nevada Las Vegas	Las Vegas, NV	1	$416,625	$0
Texas A&m Agrilife Research	College Station, TX	1	$404,584	$0
Univ of Arkansas for Med Scis	Little Rock, AR	1	$221,105	$0
University of Hawaii	Honolulu, HI	1	$156,500	$0
Johns Hopkins University	Baltimore, MD	1	$48,974	$0
University of Pennsylvania	Philadelphia, PA	1	$36,803	$0

Funding by fiscal year

Fiscal year	NIH awards	NIH amount	NSF amount
2025	26	$17,741,419	$0
2024	28	$25,107,112	$0
2023	16	$11,285,996	$0
2022	10	$13,400,994	$0
2021	10	$8,237,429	$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunity	Number	Agency	Listing	Closes	Award ceiling	Why it matches
Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required)	RFA-AI-27-002	NIH	93.855	November 10, 2026	Not listed	Same assistance listing 93.855 as 30 awards here
Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)	RFA-AI-27-005	NIH	93.855	November 10, 2026	Not listed	Same assistance listing 93.855 as 30 awards here
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)	PAR-25-370	NIH	93.855	November 16, 2026	$50,000	Same assistance listing 93.855 as 30 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)	PAR-25-369	NIH	93.855	November 18, 2026	Not listed	Same assistance listing 93.855 as 30 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)	PAR-25-371	NIH	93.855	November 18, 2026	Not listed	Same assistance listing 93.855 as 30 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)	PAR-25-379	NIH	93.855	January 7, 2027	Not listed	Same assistance listing 93.855 as 30 awards here
HIV/AIDS Clinical Trials Network Leadership and Operations Centers	RFA-AI-28-001	NIH	93.855	January 22, 2027	Not listed	Same assistance listing 93.855 as 30 awards here
HIV/AIDS Clinical Trials Network Laboratory Centers	RFA-AI-28-002	NIH	93.855	January 22, 2027	Not listed	Same assistance listing 93.855 as 30 awards here
HIV/AIDS Clinical Trials Network Statistical and Data Management Centers	RFA-AI-28-003	NIH	93.855	January 22, 2027	Not listed	Same assistance listing 93.855 as 30 awards here
HIV/AIDS Clinical Trials Network Clinical Trials Units	RFA-AI-28-004	NIH	93.855	January 22, 2027	Not listed	Same assistance listing 93.855 as 30 awards here
Precision and Systems Biology to Uncover the Link Between Chronic and Infectious Diseases	RFA-AI-28-014	NIH	93.855	January 22, 2027	Not listed	Same assistance listing 93.855 as 30 awards here
Immune Tolerance Network (UM1 Clinical Trial Required)	RFA-AI-28-005	NIH	93.855	January 29, 2027	Not listed	Same assistance listing 93.855 as 30 awards here
Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)	RFA-AI-28-012	NIH	93.855	January 29, 2027	Not listed	Same assistance listing 93.855 as 30 awards here
Accelerating Research and Development of Next Generation Vaccines against Malaria - a Model for Mosquito-Borne Diseases (R61/R33 Clinical Trial Not Allowed)	RFA-AI-28-024	NIH	93.855	February 11, 2027	Not listed	Same assistance listing 93.855 as 30 awards here
NLM Institutional Grants for Research Training in Biomedical Informatics, Data Science, and AI (T15 Independent Clinical Trial Not Allowed)	RFA-LM-28-001	NIH	93.855	February 11, 2027	$775,000	Same assistance listing 93.855 as 30 awards here
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)	PA-27-100	NIH	93.855	April 5, 2027	Not listed	Same assistance listing 93.855 as 30 awards here
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)	PA-27-102	NIH	93.855	April 5, 2027	Not listed	Same assistance listing 93.855 as 30 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)	PA-24-176	NIH	93.855	May 7, 2027	Not listed	Same assistance listing 93.855 as 30 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)	PA-24-185	NIH	93.855	May 7, 2027	Not listed	Same assistance listing 93.855 as 30 awards here
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Required)	PA-24-187	NIH	93.855	May 7, 2027	Not listed	Same assistance listing 93.855 as 30 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.