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Data / Research funding / Natural Products

Natural Products: 856 NIH awards ($1.1B) to 277 organizations

856 NIH awards ($1.1B) in the NIH spending category Natural Products, to 277 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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NIH spending category

Awards

The 500 largest of 856 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
SCREENING OF INVESTIGATIONAL AGENTS THROUGH THE NINDS PRECLINICAL SCREENING PLATFORM FOR PAIN (PSPP)NIHNational Institute on Drug Abuse2024 to 2025$21,254,211September 6, 2024September 5, 2026HANANIA, TALEENreporter.nih.gov
West Virginia IDeA Network of Biomedical Research Excellence (WV-INBRE)NIHNational Institute of General Medical Sciences2021 to 2025$20,261,619September 30, 2001July 31, 2029JOSHI, TRUPTIreporter.nih.gov
Discovery of Chemical Probes and Therapeutic Leads, Phase IINIHNational Institute of General Medical Sciences2021 to 2024$12,886,039September 1, 2014June 30, 2026FOX, JOSEPH Mreporter.nih.gov
Cannabidiol in the treatment of opioid use disorderNIHNational Institute on Drug Abuse2024$10,316,590September 30, 2019August 31, 2027HURD, YASMIN L.reporter.nih.gov
TO AWARD THE BASE PERIOD FOR NIMH PSYCHOACTIVE DRUG SCREENING PROGRAM (PDSP). BASE POP: 08/30/2023-08/29/2024.NIHNational Institute on Drug Abuse2023 to 2025$8,957,809August 30, 2023August 29, 2026ROTH, BRYANreporter.nih.gov
Rocky Mountain Cannabis Research CenterNIHNational Institute on Drug Abuse2023 to 2025$8,380,548September 1, 2023June 30, 2028HUTCHISON, KENT E.reporter.nih.gov
Development of SBS-226, a MOR agonist / DOR antagonist, for OUDNIHNational Institute on Drug Abuse2024 to 2025$7,941,988September 30, 2024August 31, 2027REICH, JEFFREYreporter.nih.gov
Microbial Chemical Sensing and Host ResponsesNIHNational Institute of General Medical Sciences2021 to 2025$7,729,035April 1, 2021June 30, 2026CRAWFORD, JASON MICHAELreporter.nih.gov
REGISTRATION, STORAGE AND DISTRIBUTION OF CHEMICALS AND DRUGS FOR PRE-CLINICAL DISCOVERY, EVALUATION AND DEVELOPMENTNIHNational Cancer Institute2023 to 2025$7,231,030March 1, 2024February 28, 2025SCHROCK, RICHARDreporter.nih.gov
Elucidating single cell changes in neurogenic brain regions during HIV and cannabinoid exposureNIHNational Institute on Drug Abuse2023 to 2025$7,084,951May 15, 2023March 31, 2028NDHLOVU, LISHOMWA Creporter.nih.gov
Integrative Multidisciplinary Discovery Platform to Unlock Marine Natural Products Therapeutic OpportunitiesNIHNational Institute of General Medical Sciences2022 to 2025$7,069,063August 1, 2022July 31, 2027LUESCH, HENDRIKreporter.nih.gov
PhytoSERM Efficacy to Prevent Menopause Associated Decline in Brain Metabolism and Cognition: A Double-Blind, Randomized, Placebo-Controlled Phase 2 Clinical TrialNIHNational Institute on Aging2022 to 2025$6,295,083February 15, 2022January 31, 2027BRINTON, ROBERTA EILEENreporter.nih.gov
Natural products as probes of the pain pathwayNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$5,820,560December 15, 2017November 30, 2025JULIUS, DAVIDreporter.nih.gov
Scalable Synthesis and New Bond DisconnectionsNIHNational Institute of General Medical Sciences2021 to 2025$5,750,475April 1, 2016November 30, 2026BARAN, PHIL Sreporter.nih.gov
Drug Induced Liver Injury Network Data Coordinating CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$5,081,421September 30, 2003July 31, 2028BARNHART, HUIMAN Xreporter.nih.gov
Achieving specificity in imaging neurodegeneration with visible light Optical Coherence TomographyNIHOffice of the Director, National Institutes of Health2024 to 2025$4,798,178September 15, 2024September 14, 2027SRINIVASAN, VIVEK JAYreporter.nih.gov
Opioid use disorders: UF Pharmacy medications discovery and developmentNIHNational Institute on Drug Abuse2021 to 2023$4,479,677December 15, 2018November 30, 2024MCCURDY, CHRISTOPHER Rreporter.nih.gov
Translational Studies of Cannabis Administration, Cognition, and the Endocannabinoid System in HIVNIHNational Institute on Drug Abuse2021 to 2025$4,324,439May 1, 2021July 31, 2026MINASSIAN, ARPIreporter.nih.gov
TrmD-targeting actinobacterial natural products as next generation antibioticsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,187,325June 25, 2021May 31, 2027HOU, YA-MINGreporter.nih.gov
Site-Selective Catalysis for Bioactive Scaffold DiversificationNIHNational Institute of General Medical Sciences2021 to 2025$4,180,650June 1, 2019May 31, 2029MILLER, SCOTT Jreporter.nih.gov
Unified Computation Tools for Natural Products researchNIHNational Institute of General Medical Sciences2021 to 2025$4,056,858September 5, 2013August 31, 2029GERWICK, WILLIAM HENRYreporter.nih.gov
Novel therapeutic approaches to treatment of botulinum neurotoxin poisoningNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,954,829April 15, 2011June 30, 2027ICHTCHENKO, KONSTANTINreporter.nih.gov
Evaluation of Cannabidiol for Reduction of Brain NeuroinflammationNIHNational Institute on Drug Abuse2021 to 2025$3,931,875June 1, 2021March 31, 2027LOGGIA, MARCO LUCIANOreporter.nih.gov
The Center for High Content Functional Annotation of Natural ProductsNIHNational Center for Complementary & Integrative Health2021 to 2024$3,906,784September 1, 2015June 30, 2025MACMILLAN, JOHN Breporter.nih.gov
The role of hypoxia in venous neointimal hyperplasia in hemodialysis graftsNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,815,411February 1, 2010April 30, 2028MISRA, SANJAYreporter.nih.gov
A Next-Generation Scalable Platform to Discover Antimicrobials of Ribosomal OriginNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,775,416March 25, 2019May 31, 2029ZHAO, HUIMINreporter.nih.gov
Unusual Pharmacophores and New Tools for Cross-CouplingNIHNational Institute of General Medical Sciences2021 to 2025$3,734,184April 1, 2017March 31, 2027SHENVI, RYAN ASHOKreporter.nih.gov
Cannabis and Pathogenic Mechanisms influencing Blood Brain Barrier Function in HIVNIHNational Institute on Drug Abuse2023 to 2025$3,726,178August 15, 2023June 30, 2028IUDICELLO, JENNIFER Ereporter.nih.gov
Chemical Synthesis of Complex Natural Products for Translational ScienceNIHNational Institute of General Medical Sciences2021 to 2025$3,701,049May 1, 2016August 31, 2026PORCO, JOHN A.reporter.nih.gov
Understanding the role of senescence on post-operative neuroinflammationNIHNational Institute on Aging2022 to 2025$3,674,270September 15, 2022August 31, 2027VARGHESE, SHYNIreporter.nih.gov
Development of a Safer and More Effective Ibogaine Analog for the Treatment of Opioid Use DisorderNIHNational Institute on Drug Abuse2024 to 2025$3,588,425March 1, 2024October 17, 2025MAREK, GERARD JOSEPHreporter.nih.gov
Effects of Cannabidiol and Tetrahydrocannabinol on the Microbiome, Endocannabinoids and Neuroinflammation in HIVNIHNational Institute on Drug Abuse2022 to 2025$3,584,464June 15, 2022March 31, 2027ELLIS, RONALD J.reporter.nih.gov
Cannabidiol for postoperative Opioid Reduction in primary total Knee arthroplasty – a randomized, 2x2 factorial, double-blind, placebo-controlled clinical trial (The CORK trial)NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$3,579,362September 18, 2023August 31, 2028BRUMMETT, CHAD Mreporter.nih.gov
Inter- and Intra-cellular effects of cannabinoids, HIV and ART in the CNSNIHNational Institute on Drug Abuse2021 to 2025$3,529,874August 1, 2020May 31, 2027JORDAN-SCIUTTO, KELLY Lreporter.nih.gov
Phase 1 study of oral epigallocatechin-3-gallate (EGCG) in IPF patientsNIHNational Heart, Lung, and Blood Institute2024 to 2025$3,521,973August 31, 2024April 30, 2027MARTINEZ, FERNANDO Jreporter.nih.gov
Metalloenzymes and metal homeostasisNIHNational Institute of General Medical Sciences2021 to 2025$3,495,303April 1, 2016March 31, 2026ROSENZWEIG, AMY C.reporter.nih.gov
Renewal: Strategies and Methods for Complex Molecule SynthesisNIHNational Institute of General Medical Sciences2021 to 2025$3,491,989January 1, 2019December 31, 2027SARPONG, RICHMONDreporter.nih.gov
Development of New Strategies for Chemical Synthesis and Study of Complex Natural ProductsNIHNational Institute of General Medical Sciences2021 to 2025$3,479,127May 1, 2021May 31, 2026MOVASSAGHI, MOHAMMADreporter.nih.gov
Characteristics of Botulinum Neurotoxins the Determine PotencyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,427,741January 18, 2019June 30, 2029PELLETT, SABINEreporter.nih.gov
Molecular underpinnings of the developmental Effects of CannabisNIHNational Institute on Drug Abuse2022 to 2025$3,375,521August 15, 2022May 31, 2027HURD, YASMIN L.reporter.nih.gov
COCOA flavanols to improve walking performance in PAD: the COCOA-PAD II TrialNIHNational Institute on Aging2021 to 2025$3,367,372July 1, 2021June 30, 2027MCDERMOTT, MARY MCGRAEreporter.nih.gov
Longitudinal assessment of benefits and harms of cannabis use among community-based cancer patients during initial cancer treatmentNIHNational Cancer Institute2023 to 2025$3,343,401September 19, 2023August 31, 2028POTOSKY, ARNOLD Lreporter.nih.gov
Exploiting Unconventional Building Blocks in Chemical SynthesisNIHNational Institute of General Medical Sciences2021 to 2025$3,314,724February 1, 2021July 31, 2025GARG, NEIL K.reporter.nih.gov
Targeted Delivery of Therapeutics into Motor Neurons for Post-exposure Treatment of BotulismNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,307,348August 1, 2021July 31, 2027DONG, MINreporter.nih.gov
Epigenetic mechanisms underlying cannabinoid modulation of neuroinflammation in HIV/SIV infectionNIHNational Institute on Drug Abuse2021 to 2024$3,267,557September 30, 2020June 30, 2026MOHAN, MAHESHreporter.nih.gov
NP-MRD: Natural Products Magnetic Resonance DatabaseNIHNational Center for Complementary & Integrative Health2021 to 2024$3,264,473July 1, 2020June 30, 2026CORT, JOHN Rreporter.nih.gov
MIRA: Enzymology and Self-Resistance of Natural Product BiosynthesisNIHNational Institute of General Medical Sciences2021 to 2025$3,260,469May 1, 2016March 31, 2026TANG, YIreporter.nih.gov
Indoles from commensal microbiota promote mobility during agingNIHNational Institute on Aging2025$3,251,767September 1, 2025August 31, 2029KALMAN, DANIELreporter.nih.gov
Effects of full-spectrum cannabidiol on alcohol consumption and alcohol use disorder phenotypes: implications for precision medicineNIHNational Institute on Alcohol Abuse and Alcoholism2025$3,227,517September 20, 2025August 31, 2029KAROLY, HOLLIS Creporter.nih.gov
Synthesis and Evaluation of Carbohydrate Vaccine AdjuvantsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,192,190June 10, 2022May 31, 2027NGUYEN, HIEN Mreporter.nih.gov
Peripherally-restricted non-addictive cannabinoids for cancer pain treatmentNIHNational Institute of Neurological Disorders and Stroke2023$3,174,343August 1, 2023July 31, 2025SPIGELMAN, IGORreporter.nih.gov
ERP studies of acute influences of THC and CBD on memory encoding and retrieval processesNIHNational Institute on Drug Abuse2021 to 2025$3,173,683August 1, 2021May 31, 2027CURRAN, TIMOTHY Ereporter.nih.gov
Neural and Behavioral Consequences of Chronic THC Exposure During AdolescenceNIHNational Institute on Drug Abuse2021 to 2025$3,173,342July 1, 2019March 31, 2030BERGMAN, JACKreporter.nih.gov
Chemical Synthesis of Chiral Bioactive MoleculesNIHNational Institute of General Medical Sciences2021 to 2025$3,165,278May 1, 2016June 30, 2026REISMAN, SARAH ELIZABETHreporter.nih.gov
Modulation of pain mechanisms by cannabis-derived phytochemicals.NIHNational Center for Complementary & Integrative Health2021 to 2025$3,150,461December 1, 2020November 30, 2026SETO, TODD Breporter.nih.gov
Macrophage senescence as a driver of granuloma failure and progression to necrosis in TB and TB/HIVNIHNational Institute of Allergy and Infectious Diseases2025$3,145,850September 19, 2025August 31, 2029BISHAI, WILLIAM RAMSESreporter.nih.gov
Genomics-Assisted Antibiotic Discovery from Unprecedented Microbes of the Great Salt LakeNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,135,301July 12, 2021April 30, 2027WINTER, JACLYN MARIEreporter.nih.gov
Microbiota, Metabolites, and Colon NeoplasiaNIHNational Cancer Institute2021 to 2025$3,124,761May 1, 2021April 30, 2027ROSENBERG, DANIEL WILLIAMreporter.nih.gov
GENETIC TOXICOLOGY SUPPORT FOR THE NTP AND THE NIEHSNIHNational Institute of Environmental Health Sciences2021 to 2024$3,123,963September 6, 2020September 5, 2025HOBBS, CHERYL A.reporter.nih.gov
Discriminative Stimulus Effects of Opioid WithdrawalNIHNational Institute on Drug Abuse2021 to 2025$3,097,773May 1, 1995December 31, 2026FRANCE, CHARLES Preporter.nih.gov
Analgesic and subjective effects of terpenes administered alone and in combination with THC: Potential THC- and opioid-sparing effects of myrcene and ß-caryophylleneNIHNational Center for Complementary & Integrative Health2021 to 2025$3,089,484February 15, 2020January 31, 2026COOPER, ZIVA Dreporter.nih.gov
MAEVE: Microbiota mediated flavonoid metabolites for cognitive healthNIHNational Institute on Aging2024 to 2025$3,084,260July 15, 2024June 30, 2029CHURCH, ARPANAreporter.nih.gov
Use of De Novo Synthesis Approaches and Structure-guided Design to Optimize Therapeutic Properties of Streptothricin Class AntimicrobialsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,077,792September 23, 2020August 31, 2025KIRBY, JAMES Ereporter.nih.gov
Computation and Development of New, Enabling Synthetic MethodsNIHNational Institute of General Medical Sciences2021 to 2025$3,060,360June 1, 2019May 31, 2029KOZLOWSKI, MARISA Creporter.nih.gov
Cannabis use among older adults: Potential risks and benefits to an aging populationNIHNational Institute on Aging2021 to 2025$3,055,285February 15, 2021January 31, 2027BRYAN, ANGELAreporter.nih.gov
Single Cell Methods for Bioeffector Discovery and AnalysisNIHNational Cancer Institute2021 to 2025$3,031,845December 18, 2018July 31, 2029BACHMANN, BRIAN Oreporter.nih.gov
Enhancing parasympathetic activity to reduce vascular oxidative stress and endothelial dysfunctionNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,026,236June 1, 2021May 31, 2026SHIBAO, CYNDYA ADRIANAreporter.nih.gov
Novel Antimalarials from FungiNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,025,049May 18, 2020April 30, 2026CHAKRABARTI, DEBOPAMreporter.nih.gov
Symbiotic-based discovery of turbinmicin, a safe and selective antifungal against resistant fungiNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,015,316March 4, 2022February 28, 2027ANDES, DAVID Rreporter.nih.gov
AIM(2)ing at the inflammasome: Impact of MAVS signaling in cocaine-and HIV-1 induced neuroinflammationNIHNational Institute on Drug Abuse2021 to 2025$3,004,104March 15, 2021February 28, 2027CISNEROS, IRMAreporter.nih.gov
The role of cannabinoids in the regulation of the blood brain barrier in the context of NeuroHIV and anti-retroviral therapyNIHNational Institute on Drug Abuse2021 to 2025$2,992,059April 1, 2021December 31, 2025PERSIDSKY, YURIreporter.nih.gov
Synthetic and translational studies of antitumor and antimicrobial natural products.NIHNational Institute of General Medical Sciences2021 to 2025$2,988,144May 1, 2019April 30, 2029HERZON, SETH B.reporter.nih.gov
Effects of cannabis on age-related cognitive decline and Alzheimers disease pathologyNIHNational Institute on Aging2021 to 2025$2,987,650August 15, 2021May 31, 2027SETLOW, BARRYreporter.nih.gov
Development of KLS-13019 for Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,970,772September 30, 2021August 31, 2025BRENNEMAN, DOUGLAS ERICreporter.nih.gov
Rapid dissection of the biosynthesis of antiMRSA antibiotics produced in co-culture by extremophilic fungi through the development of Fungal Artificial ChromosomesNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,942,798July 1, 2022December 31, 2025WU, CHENGCANG CHARLESreporter.nih.gov
Enhancing Children's Cognitive Function and Achievement through Carotenoid ConsumptionNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,916,241September 17, 2021May 31, 2027KHAN, NAIMANreporter.nih.gov
Effect of randomized cocoa supplementation on inflammaging and epigenetic agingNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,908,307July 15, 2021May 31, 2026DONG, YANBINreporter.nih.gov
Targeting PDGFR-b promoter vacancy G-quadruplex to suppress gene expressionNIHNational Cancer Institute2025$2,906,409August 1, 2025July 31, 2029YANG, DANZHOUreporter.nih.gov
Mechanism and optimization of CBD-mediated analgesic effects (Diversity Supplement)NIHNational Center for Complementary & Integrative Health2021 to 2023$2,902,023September 15, 2019June 30, 2025HE, ZHIGANGreporter.nih.gov
New Catalysts, Strategies and Methods for Stereoselective Chemical SynthesisNIHNational Institute of General Medical Sciences2021 to 2025$2,884,150January 1, 2019July 31, 2029HOVEYDA, AMIR Hreporter.nih.gov
Optimization of Cannabinoids for Development as FDA-Approved Migraine TherapeuticsNIHNational Institute on Drug Abuse2024 to 2025$2,883,639September 30, 2020August 31, 2026PAPPAS, GEORGEreporter.nih.gov
Cannabinoid interactions with central and peripheral pain mechanisms in osteoarthritis of the kneeNIHNational Center for Complementary & Integrative Health2021 to 2024$2,864,374August 1, 2020May 31, 2026HARTE, STEVEN EDWARDreporter.nih.gov
A New Class of Broad-Spectrum Antibacterial Agents to Treat Multi-Drug Resistant PathogensNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,858,436July 21, 2023June 30, 2027SEBAHAR, PAULreporter.nih.gov
CHEMICAL SYNTHESIS FACILITY FOR CONTRACEPTIVE DEVELOPMENTNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,852,434September 29, 2022September 28, 2026GURVICH, VADIMreporter.nih.gov
Opioid and cannabinoid interactions in pain and rewardNIHNational Institute on Drug Abuse2021 to 2024$2,852,096September 30, 2020June 30, 2026NEUBERT, JOHN Kreporter.nih.gov
Mechanism of Cannabidiol Effects on HIV Expression, Neuroinflammation, and HIV Cognitive Disease in Chronically-infected Immunocompetent MiceNIHNational Institute on Drug Abuse2021 to 2024$2,851,386September 30, 2020July 31, 2025VOLSKY, DAVID Jreporter.nih.gov
Discovery and mechanisms of biosynthetic enzymesNIHNational Institute of General Medical Sciences2021 to 2025$2,838,667May 1, 2018August 31, 2028BANDARIAN, VAHEreporter.nih.gov
Supratherapeutic PTX Buttresses Reduce Locoregional Recurrence Rates Following Surgery for Soft Tissue SarcomasNIHNational Cancer Institute2022 to 2025$2,833,313August 1, 2022July 31, 2027RAUT, CHANDRAJIT PREMANANDreporter.nih.gov
Selective C(sp3)-H Oxidations and Functionalizations with Tunable Metal Catalysts for SynthesisNIHNational Institute of General Medical Sciences2021 to 2025$2,805,104May 1, 2017April 30, 2027WHITE, MARIA CHRISTINAreporter.nih.gov
Cannabis Effects on Antiretroviral Therapy, Pharmacokinetics, and NeurotoxicityNIHNational Institute on Drug Abuse2021 to 2024$2,756,681July 1, 2020April 30, 2026LETENDRE, SCOTT Lreporter.nih.gov
Mechanisms of cannabidiol in persons with MS: the role of sleep and pain phenotypeNIHNational Center for Complementary & Integrative Health2021 to 2024$2,725,289August 15, 2021May 31, 2026BRALEY, TIFFANY JOYreporter.nih.gov
Assessing pharmacokinetic and pharmacodynamic variability of Δ9-tetrahydrocannabinol delivered from vaping products with and without concurrent use of nicotineNIHNational Institute on Drug Abuse2022 to 2025$2,720,537September 30, 2022June 30, 2027SMITH, DANIELLEreporter.nih.gov
New Catalytic Methods for the Synthesis of Complex MoleculesNIHNational Institute of General Medical Sciences2021 to 2025$2,719,827August 1, 2020May 31, 2030NICEWICZ, DAVID Areporter.nih.gov
Determining the function of medium to large diameter sensory neurons in paclitaxel-induced pain via large-scale in vivo DRG imagingNIHNational Cancer Institute2025$2,714,830August 6, 2025July 31, 2030ZHENG, QINreporter.nih.gov
COcoa Supplement and Multivitamins Outcomes Study (COSMOS): Effects on Falls and Physical PerformanceNIHNational Institute on Aging2021 to 2024$2,711,621May 15, 2021February 28, 2026LEBOFF, MERYL SUSANreporter.nih.gov
Cannabis' Impact on Alcohol Consumption: Integrating Laboratory and Ecological Momentary Assessment MethodsNIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2025$2,671,024April 1, 2022March 31, 2027METRIK, JANEreporter.nih.gov
Vaccines Against BotulismNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,665,989July 15, 2015May 31, 2026BARBIERI, JOSEPH Treporter.nih.gov
Chemistry and Pharmacology of Iboga AlkaloidsNIHNational Institute on Drug Abuse2021 to 2024$2,661,356June 15, 2020December 31, 2025SAMES, DALIBORreporter.nih.gov
Coffee and metabolites modulating the gut microbiome for improved colorectal cancer survivalNIHNational Cancer Institute2022 to 2025$2,628,801June 2, 2022May 31, 2027SONG, MINGYANGreporter.nih.gov
Discovery of Antibiotics from Soil Microbiomes Using MetagenomicsNIHNational Institute of General Medical Sciences2021 to 2025$2,627,250May 1, 2017August 31, 2028BRADY, SEAN Freporter.nih.gov
Development and validation of a high-throughput MicroED-driven platform technology for natural product discoveryNIHNational Center for Complementary & Integrative Health2022 to 2025$2,613,903May 6, 2022February 28, 2027QUAVE, CASSANDRA LEAHreporter.nih.gov
Systems Genetics Dissection of Non-alcoholic SteatohepatitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,612,818July 1, 2019March 31, 2028LUSIS, ALDONS JAKEreporter.nih.gov
Pre-IND Development of Polymeric Micelles with Dual Drug Payloads for HCC TherapyNIHNational Cancer Institute2022 to 2025$2,603,837August 1, 2022June 30, 2027LI, CHUNreporter.nih.gov
Microbial Ecology-Guided Discovery of Antibacterial DrugsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,576,398February 7, 2022January 31, 2027SCHMIDT, ERIC Wreporter.nih.gov
Cannabis use frequency and its impact on monocyte-mediated inflammation in HIV patientsNIHNational Institute on Drug Abuse2021 to 2025$2,570,020September 1, 2021July 31, 2027KAMINSKI, NORBERT Ereporter.nih.gov
The Use of Senolytic and Anti-Fibrotic Agents to Improve the Beneficial Effect of Bone Marrow Stem Cells for OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,563,053August 1, 2020July 31, 2025HUARD, JOHNNYreporter.nih.gov
The Synthesis of Bioactive Natural Products as a Driving Force for Discovery in Organic ChemistryNIHNational Institute of General Medical Sciences2022 to 2025$2,542,460April 1, 2022March 31, 2027STOLTZ, BRIAN Mreporter.nih.gov
PhytoSERM for Menopausal Hot Flashes and Sustained Brain HealthNIHNational Institute on Aging2022 to 2023$2,536,705September 30, 2022August 31, 2025RINEHART, JOHNreporter.nih.gov
Cannabis, inflammation, and the brain in persons with HIVNIHNational Institute on Drug Abuse2021 to 2024$2,527,684September 30, 2020June 30, 2025IUDICELLO, JENNIFER Ereporter.nih.gov
Synthesis and Chemical Biology of Bioactive Natural ProductsNIHNational Institute of General Medical Sciences2021 to 2025$2,523,386January 1, 2021December 31, 2026PIERCE, JOSHUA G.reporter.nih.gov
Cannabinoid CB2 Receptor Structure and Allosteric ModulatorsNIHNational Institute on Drug Abuse2021 to 2024$2,521,841July 15, 2021April 30, 2026XIE, XIANG-QUNreporter.nih.gov
Drug-gene-nutraceutical interactions of cannabidiolNIHNational Center for Complementary & Integrative Health2022 to 2025$2,519,234February 22, 2022January 31, 2027EADON, MICHAEL THOMASreporter.nih.gov
Bulgecin Template for Potentiation of beta-Lactam AntibioticsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,516,168July 1, 2020June 30, 2025MOBASHERY, SHAHRIARreporter.nih.gov
Cellular Senescence in Neonatal AirwaysNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,503,972July 1, 2022June 30, 2027PRAKASH, Y. S.reporter.nih.gov
Benefit and Safety of Cytisinicline (cytisine) for Cessation of Nicotine E-cigarette UseNIHNational Institute on Drug Abuse2022 to 2023$2,497,896August 1, 2021February 29, 2024JACOBS, CINDYreporter.nih.gov
Novel Approaches to Opiate Use ReductionNIHNational Institute on Drug Abuse2021 to 2024$2,469,078April 1, 2020January 31, 2026HUTCHISON, KENT E.reporter.nih.gov
“Conus venom peptides and their molecular targets: Using pharmaconomics and neuroethology as a framework for discovery”NIHNational Institute of General Medical Sciences2022 to 2025$2,461,992March 15, 2022February 28, 2026OLIVERA, BALDOMERO Mreporter.nih.gov
TOWARD TRANSLATION OF NANFORMULATED PACLITAXEL-PLATINUM COMBINATIONNIHNational Cancer Institute2021 to 2024$2,460,645August 1, 2021July 31, 2025KABANOV, ALEXANDER Vreporter.nih.gov
Behavior-based discovery of small-molecule modulators of neurochemical signaling pathways that underlie addictionNIHNational Institute on Drug Abuse2022 to 2025$2,427,182July 15, 2022May 31, 2027RINGSTAD, NIELSreporter.nih.gov
Natural Product-Inspired Approaches Toward The Development Of Antivirulence And Species-Specific InhibitorsNIHNational Institute of General Medical Sciences2021 to 2025$2,417,560June 30, 2016June 30, 2026WUEST, WILLIAM Mreporter.nih.gov
Molecular Prosthetics and Lego ChemistryNIHNational Institute of General Medical Sciences2023 to 2025$2,415,883June 1, 2016February 29, 2028BURKE, MARTIN Dreporter.nih.gov
Genetic modifiers of the Mediterranean-DASH diet Intervention for Neurodegenerative Delay (MIND) responseNIHNational Institute on Aging2021 to 2024$2,385,503September 15, 2020April 30, 2026CORNELIS, MARILYN Creporter.nih.gov
Hemp-derived Cannabidiol for the treatment of cannabis use disorder in concentrate users: A double-blind placebo-controlled randomized trialNIHNational Institute on Drug Abuse2023 to 2025$2,376,018September 15, 2023July 31, 2028BIDWELL, L. CINNAMONreporter.nih.gov
Protein-protein interactions in natural product biosynthesisNIHNational Institute of General Medical Sciences2021 to 2025$2,360,682March 1, 2012August 31, 2026BURKART, MICHAEL D.reporter.nih.gov
Synthesis and Optimization of the Aleutianamine Class of AlkaloidsNIHNational Institute of General Medical Sciences2022 to 2025$2,360,261September 1, 2022June 30, 2026HAMANN, MARK Treporter.nih.gov
Translating CBD Treatment for Heroin AddictionNIHNational Institute on Drug Abuse2021 to 2023$2,349,864August 1, 2019June 30, 2025HURD, YASMIN L.reporter.nih.gov
Mining Actinobacterial Genomes for Natural Product Discovery and BiosynthesisNIHNational Institute of General Medical Sciences2022 to 2025$2,333,969January 1, 2020January 31, 2029SHEN, BENreporter.nih.gov
Development of a Mirror-Image Natural Product as an Antiarrhythmic TherapeuticNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,330,311March 17, 2020February 28, 2025JOHNSTON, JEFFREY NICHOLASreporter.nih.gov
Biology and Engineering of Botulinum Neurotoxins.NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,317,212March 1, 2013July 31, 2029DONG, MINreporter.nih.gov
Synthesis of Bioactive Small Molecule Building BlocksNIHNational Institute of General Medical Sciences2021 to 2025$2,303,395May 1, 2016June 30, 2026JOHNSON, JEFFREY Sreporter.nih.gov
Metallacycle-mediated coupling in stereoselective synthesisNIHNational Institute of General Medical Sciences2021 to 2024$2,296,000January 1, 2020December 31, 2025MICALIZIO, GLENN Creporter.nih.gov
The Impact of Cannabidiol (CBD) Health Claims at Point-of-Sale on Consumer Perceptions and BehaviorNIHNational Institute on Drug Abuse2021 to 2025$2,287,873July 15, 2021May 31, 2027WAGONER, KIMBERLY G.reporter.nih.gov
Soy Isoflavones for Inner City Infants at Risk for Asthma (SIRA)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,286,643April 14, 2021March 31, 2028KUMAR, RAJESHreporter.nih.gov
Cannabidiol and Macrophage Chronic Inflammation in a Virally Suppressed Rhesus Macaque ModelNIHNational Institute on Drug Abuse2021 to 2023$2,266,058September 30, 2020June 30, 2025WILLIAMS, DIONNA WHITNEYreporter.nih.gov
Targeting PKR-Bcl2 Signaling to Overcome Paclitaxel Resistance in Ovarian CancerNIHNational Cancer Institute2022 to 2025$2,255,717August 1, 2022July 31, 2027DONG, JIXINreporter.nih.gov
Tryptophan derivatives in EHEC pathogenesisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,253,769August 8, 2022January 31, 2027SPERANDIO, VANESSAreporter.nih.gov
Harnessing Alkyl Amines and Alkyl Alcohols in Cross-Coupling ReactionsNIHNational Institute of General Medical Sciences2021 to 2025$2,250,697June 1, 2019May 31, 2029WATSON, MARY Preporter.nih.gov
Development of natural product inhibitors of Nef for clearance of HIV reservoirsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,246,547July 1, 2019June 30, 2025SHERMAN, DAVID Hreporter.nih.gov
Identification of gene variants mediating the behavioral and physiological response to THCNIHNational Institute on Drug Abuse2023 to 2025$2,243,926July 1, 2023April 30, 2028MULLIGAN, MEGAN KATHLEENreporter.nih.gov
GUARD: A global unbiased antimicrobial discovery platformNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,236,619November 7, 2022October 31, 2027JAYARAMAN, ARULreporter.nih.gov
Kratom alkaloids: in vitro and in vivo pharmacological mechanismsNIHNational Institute on Drug Abuse2021 to 2023$2,226,033April 15, 2019February 28, 2025MCCURDY, CHRISTOPHER Rreporter.nih.gov
New reagents for C-C and C-N bond formationNIHNational Institute of General Medical Sciences2021 to 2025$2,203,498July 1, 2021April 30, 2026LOPCHUK, JUSTIN MATTHEWreporter.nih.gov
Phase 1 study of oral epigallocatechin-3-gallate (EGCG) in IPF patientsNIHNational Heart, Lung, and Blood Institute2023 to 2024$2,201,114May 20, 2022June 25, 2024MARTINEZ, FERNANDO Jreporter.nih.gov
Understanding the clinical pharmacology of marijuana-tobacco co-administrationNIHNational Institute on Drug Abuse2023 to 2025$2,179,609May 15, 2023February 29, 2028ST.HELEN, GIDEONreporter.nih.gov
The Effects of Cannabinoids and Route of Cannabis Administration on Subclinical Cardiovascular Disease RiskNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,169,132August 1, 2020June 30, 2025VIDOT, DENISE CHRISTINAreporter.nih.gov
Caffeine and Postoperative Neurocognitive RecoveryNIHNational Institute on Aging2022 to 2025$2,166,523August 2, 2022April 30, 2027VLISIDES, PHILLIP ELEASreporter.nih.gov
Modulating single cell types in the sensory nervous systemNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,152,157July 1, 2022June 30, 2027SCHMIDT, ERIC Wreporter.nih.gov
Cannabidiol for Individuals at Risk for Alzheimer's Disease: A Randomized Placebo Controlled TrialNIHNational Institute on Aging2023 to 2025$2,143,253July 1, 2023June 30, 2028HUTCHISON, KENT E.reporter.nih.gov
Late Stage Stereochemical Editing to Transform the Synthesis of Bioactive MoleculesNIHNational Institute of General Medical Sciences2021 to 2024$2,143,149September 23, 2021August 31, 2026WENDLANDT, ALISONreporter.nih.gov
Role of PXR in drug-elicited cardiovascular diseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,135,638December 15, 2022November 30, 2026ZHOU, CHANGCHENGreporter.nih.gov
Mining Cryptic Biosynthetic Gene Clusters for Novel Bioactive Compounds and BiocatalystsNIHNational Institute of General Medical Sciences2021 to 2025$2,126,227July 1, 2020May 31, 2030PARKINSON, ELIZABETH IVYreporter.nih.gov
Sex-dependent effects of cannabis: Assessing abuse-related and pharmacokinetic differences between men and womenNIHNational Institute on Drug Abuse2021 to 2024$2,123,819September 15, 2019June 30, 2026COOPER, ZIVA Dreporter.nih.gov
Validation of Retinal Abeta as a Potential Biomarker of Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2023$2,113,690September 1, 2019November 30, 2025PHAM, WELLINGTONreporter.nih.gov
Impact of maternal marijuana use on epigenetic regulation of offspring neurodevelopmentNIHNational Institute on Drug Abuse2022 to 2025$2,100,000September 15, 2022August 31, 2027LO, JAMIEreporter.nih.gov
Brain and behavior correlates of prenatal cannabis exposureNIHNational Institute on Drug Abuse2023 to 2025$2,095,376July 15, 2023May 31, 2028KLEINHANS, NATALIA Mreporter.nih.gov
High-Throughput NMJ Assay for Botox Potency ScreeningNIHNational Center for Advancing Translational Sciences2023 to 2025$2,086,960August 1, 2023January 31, 2027GEISSE, NICHOLAS ANDREWreporter.nih.gov
Modeling CNS dynamics in HIV infection and cannabinoids with forebrain organoidsNIHNational Institute on Drug Abuse2021 to 2023$2,085,642August 1, 2019June 30, 2025JORDAN-SCIUTTO, KELLY Lreporter.nih.gov
Prenatal alcohol/cannabinoid co-exposures and fetal brain developmentNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$2,076,761May 1, 2020April 30, 2026MIRANDA, RAJESH Creporter.nih.gov
Life’s end Benefits of CannaBidiol and TetrahYdrocannabinol (LiBBY) Open-Label Extension (OLE) StudyNIHNational Institute on Aging2025$2,072,617August 15, 2025July 31, 2028MINTZER, JACOBOreporter.nih.gov
Mapping and Understanding Production of Natural Products in FungiNIHNational Center for Complementary & Integrative Health2022 to 2025$2,063,341April 1, 2016May 31, 2027KELLEHER, NEIL Lreporter.nih.gov
Pharmacophore - Directed Retrosynthesis Applied to Bioactive Natural Products Informing Mechanism of Action StudiesNIHNational Institute of General Medical Sciences2021 to 2025$2,056,227January 1, 2020December 31, 2029ROMO, DANIELreporter.nih.gov
SimplePath II: A Cell-free Enzymatic Platform for Cannabinoid BiosynthesisNIHNational Center for Complementary & Integrative Health2021 to 2023$2,054,674September 1, 2021August 31, 2024KORMAN, TYLER Preporter.nih.gov
Effects of High Potency Cannabis Products on Mental Health and Psychosocial FunctioningNIHNational Institute on Drug Abuse2023 to 2025$2,053,256May 15, 2023March 31, 2028HOPFER, CHRISTIAN Jreporter.nih.gov
Cannabidiol/Palmitoylethanolamide sublingual tablets for the treatment of Painful Diabetic Peripheral NeuropathyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2024$2,051,325September 20, 2023July 31, 2025KIMLESS, DEBRAreporter.nih.gov
Preclinical Assessment of Medications for Alcohol AbuseNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2023$2,042,668September 28, 2007March 31, 2025WEERTS, ELISE Mreporter.nih.gov
Synthetic biology tools for scalable production of medicinal plant terpenesNIHNational Center for Complementary & Integrative Health2021 to 2023$2,036,524September 15, 2019June 30, 2025SATTELY, ELIZABETH SUSANreporter.nih.gov
Alcohol Use Disorder and Cannabis: Testing Novel Harm Reduction StrategiesNIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2025$2,030,405April 20, 2022March 31, 2027HUTCHISON, KENT E.reporter.nih.gov
Targeting Senescence to Mitigate Chemotherapy-induced Functional DeclineNIHNational Cancer Institute2023 to 2025$2,026,604September 1, 2023August 31, 2028SEDRAK, MINA Sreporter.nih.gov
A Drug Discovery Platform to Prioritize Development of Natural Product Neuromodulators for Treating Cognitive ImpairmentNIHNational Institute on Aging2024 to 2025$2,019,940December 1, 2023March 31, 2027BROWN, JEFFREY M.reporter.nih.gov
Chemoenzymatic Synthesis, Mode of Action and Evolution of Natural Product-based MacrocyclesNIHNational Institute of General Medical Sciences2021 to 2025$2,015,905September 5, 2017August 31, 2027BOWERS, ALBERT Areporter.nih.gov
Effect of Microbial Metabolites on Growth of CryptosporidiumNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,012,133December 13, 2019November 30, 2024SIBLEY, L. DAVIDreporter.nih.gov
In vivo study of THC-induced immunogenome changes at single cell resolution in HIV-infected humansNIHNational Institute on Drug Abuse2021 to 2025$2,010,652September 30, 2020June 30, 2027XU, KEreporter.nih.gov
Mechanisms and Evolution of Assembly-Line Polyketide SynthasesNIHNational Institute of General Medical Sciences2021 to 2025$2,008,493June 1, 2021May 31, 2026KHOSLA, CHAITANreporter.nih.gov
Novel approaches to assessing cannabis impaired drivingNIHNational Institute on Drug Abuse2021 to 2024$2,006,137July 1, 2020October 31, 2025BROOKS-RUSSELL, ASHLEYreporter.nih.gov
BASE IDIQ TITLE: PREVENT CANCER PRECLINICAL DRUG DEVELOPMENT PROGRAM: PRECLINICAL EFFICACY AND INTERMEDIATE ENDPOINT BIOMARKERSTASK ORDER TITLE: FURTHER DEVELOPMENT OF MITOCHONDRIA-TARGETED HONOKIOLNIHNational Cancer Institute2024 to 2025$2,002,559September 25, 2025March 24, 2028reporter.nih.gov
Assigning mode of action to phenotypically discovered anticancer leads.NIHNational Cancer Institute2023 to 2024$2,000,000September 21, 2023July 31, 2025MAKAROV, SERGEI Sreporter.nih.gov
Human NeuromuscularJunction Platform to Evaluate Botulinum Toxin PotencyNIHNational Center for Advancing Translational Sciences2024 to 2025$2,000,000April 24, 2024March 31, 2026KRONAUGE, JAMES Freporter.nih.gov
New oral antibiotics focused on treating MDR Gram-negative infectionsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,000,000July 9, 2024June 30, 2027TESTA, CHARLESreporter.nih.gov
A new class of antibiotic to address Antimicrobial ResistanceNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,999,995May 1, 2024April 30, 2027TESTA, CHARLESreporter.nih.gov
A microbial engineering platform for sustainable, scalable, and cost-effective production of pharmaceutical grade cannabinoids and related compoundsNIHNational Center for Complementary & Integrative Health2024 to 2025$1,999,908May 16, 2024April 30, 2026KAMBOURAKIS, SPIROSreporter.nih.gov
Ceraxa (Ceramide NanoLiposome) and Vinblastine For the Improved Treatment of Relapsed or Refractory Acute Myeloid LeukemiaNIHNational Cancer Institute2022 to 2023$1,999,256September 14, 2022August 31, 2025ADAIR, BERNADETTE MCMAHONreporter.nih.gov
Defining the impact of cannabinoids on the latent HIV reservoir through multi-omic analysisNIHNational Institute on Drug Abuse2021 to 2023$1,995,250July 1, 2021May 31, 2024BROWNE, EDWARD Preporter.nih.gov
Biomarkers of Dietary Flavonoid Intake, Carbonyl Stress, and Metabolic RiskNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$1,983,942August 1, 2022May 31, 2027SANG, SHENGMINreporter.nih.gov
Influence of bacterial tryptophan metabolism on inflammatory arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,982,751April 10, 2019July 31, 2029KUHN, KRISTINE A.reporter.nih.gov
Novel Targeted Anticancer Agents from Marine CyanobacteriaNIHNational Cancer Institute2021 to 2025$1,978,529March 6, 2013January 31, 2030LUESCH, HENDRIKreporter.nih.gov
Targeting immunoproteasome-mediated antigen presentation in colorectal cancer immunotherapyNIHNational Cancer Institute2022 to 2025$1,972,182January 1, 2022December 31, 2026ZHANG, XINNAreporter.nih.gov
Discovery and Biosynthesis of Bacterial TerpenoidsNIHNational Institute of General Medical Sciences2021 to 2025$1,950,115August 1, 2021July 31, 2026RUDOLF, JEFFREY DANIELreporter.nih.gov
Tethered aza-Wacker Technology for Complex Antibiotic AssemblyNIHNational Institute of General Medical Sciences2021 to 2025$1,930,783September 1, 2021July 31, 2027SATHYAMOORTHI, SHYAMreporter.nih.gov
Synthesis, Structure, and Mechanism of Biorelevant Molecules and ReactionsNIHNational Institute of General Medical Sciences2021 to 2025$1,930,646April 1, 2018July 31, 2028HOYE, THOMAS R.reporter.nih.gov
Indole dysbiosis and mucosal inflammationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,930,131June 1, 2012December 31, 2028COLGAN, SEAN Preporter.nih.gov
Assessing Benefits and Harms of Cannabis and Cannabinoid Use Among a Cohort of Cancer Patients Treated in Community Oncology ClinicsNIHNational Cancer Institute2023 to 2025$1,930,054September 21, 2023August 31, 2028REBOUSSIN, BETH A.reporter.nih.gov
Accessing and expanding microbial bioactive chemical diversity by synthetic biology and new enzymologyNIHNational Institute of General Medical Sciences2021 to 2025$1,927,447July 1, 2018June 30, 2028DING, YOUSONGreporter.nih.gov
Discovery and Characterization of Natural Product SystemsNIHNational Institute of General Medical Sciences2021 to 2025$1,917,817June 1, 2016May 31, 2026SHERMAN, DAVID Hreporter.nih.gov
Cannabis for Palliative Care in Cancer: A Placebo-controlled Randomized Trial of Full Spectrum Hemp-derived CBD/THCNIHNational Cancer Institute2023 to 2025$1,915,200August 1, 2023July 31, 2028BRYAN, ANGELAreporter.nih.gov
Machine learning approaches for the discovery, repurposing, and optimization of natural products with therapeutic potentialNIHNational Institute of General Medical Sciences2022 to 2025$1,912,959September 1, 2022August 31, 2027WALKER, ALLISON SARAreporter.nih.gov
Biochemistry and Pharmacology of the Macular CarotenoidsNIHNational Eye Institute2021 to 2025$1,908,354August 1, 1997April 30, 2027BERNSTEIN, PAUL STEVENreporter.nih.gov
Covalent Inhibition as a Method to Counteract Botulinum IntoxicationNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,905,848June 2, 2020November 30, 2024JANDA, KIMreporter.nih.gov
Synthesis and Evaluation of Alkaloids to Probe Membrane ReceptorsNIHNational Institute of General Medical Sciences2022 to 2025$1,905,708August 1, 2022June 30, 2027RILEY, ANDREWreporter.nih.gov
Quercetin prevent airway epithelial remodeling and promote lung health in OPDNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,898,463July 1, 2021June 30, 2025SAJJAN, UMADEVI SIVANAPPAreporter.nih.gov
Heme-Dependent Chemistry in Aromatic OxidationNIHNational Institute of General Medical Sciences2021 to 2025$1,887,949August 1, 2014August 31, 2026LIU, AIMINreporter.nih.gov
Development of an intravenous CB1 antagonist for acute cannabinoid intoxication and cannabis hyperemesis syndromeNIHNational Institute on Drug Abuse2024 to 2025$1,886,590August 1, 2024July 31, 2026CUNDY, KENNETHreporter.nih.gov
Halogenation Biochemistry in Human and Environmental HealthNIHNational Institute of General Medical Sciences2021 to 2025$1,868,760July 1, 2021April 30, 2027AGARWAL, VINAYAKreporter.nih.gov
Bio-Responsive and Immune Protein-Based Therapies for Inhibition of Proteolytic Enzymes in Dental TissuesNIHNational Institute of Dental & Craniofacial Research2023 to 2025$1,867,660March 17, 2023February 28, 2028PIOVEZAN FUGOLIN, ANA PAULAreporter.nih.gov
Novel neuroprotective activities of flavonoids against retinal degenerative diseasesNIHNational Eye Institute2022 to 2025$1,867,600September 30, 2022May 31, 2026JASTRZEBSKA, BEATAreporter.nih.gov
Genetic Basis of the Risk and Consequences of Cannabis Exposure in HumansNIHNational Institute on Drug Abuse2023 to 2025$1,866,314September 30, 2023July 31, 2028D'SOUZA, DEEPAK CYRILreporter.nih.gov
Aging-associated mammary cancer-initiating cellsNIHNational Cancer Institute2021 to 2025$1,860,500September 17, 2021August 31, 2026SUN, LUZHEreporter.nih.gov
Validation of biomarkers of infant and toddler carotenoid intakeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,852,489May 1, 2023April 30, 2028MORAN, NANCY Ereporter.nih.gov
Targeting Inflammasome with stable endocannabinoid ligand AMG315. CRISPR/Cas9 and nanotechnology study in the context of HIV and cannabinoidNIHNational Institute on Drug Abuse2021 to 2024$1,847,120July 1, 2020May 31, 2026LAKSHMANA, MADEPALLI KRISHNAPPAreporter.nih.gov
Functional implications of stroke and Botulinum Neurotoxin on ankle stiffness and viscosity during gaitNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,843,778May 1, 2023March 31, 2028ROUSE, ELLIOTT Jreporter.nih.gov
Evolution and consequences of multidrug resistant ribosomeNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,843,401September 16, 2020August 31, 2025YAP, M.-N. FRANCESreporter.nih.gov
New Methods and Strategies for the Synthesis and Selective Derivatization of Natural ProductsNIHNational Institute of General Medical Sciences2021 to 2025$1,840,796May 2, 2020March 31, 2030NAGORNY, PAVELreporter.nih.gov
HIV-1 Neurotoxicity: Mechanism & Modulation by CannabinoidsNIHNational Institute on Drug Abuse2021 to 2024$1,839,474March 15, 1992February 28, 2026THAYER, STANLEY Areporter.nih.gov
Structure and Function of Biosynthetic EnzymesNIHNational Institute of General Medical Sciences2021 to 2025$1,838,353August 1, 1998August 31, 2026CHRISTIANSON, DAVID Wreporter.nih.gov
Mechanistic investigations of microbiome-driven aryl hydrocarbon receptor activity and macrophage function in pancreatic cancer.NIHNational Cancer Institute2021 to 2025$1,832,774May 1, 2021April 30, 2026MCGAHA, TRACY Lreporter.nih.gov
Blood-brain barrier disruption with implantable ultrasound to enhance paclitaxel delivery: A Phase 1-2 clinical trial in recurrent glioblastomaNIHNational Cancer Institute2021 to 2024$1,825,419September 15, 2020June 30, 2026SONABEND, ADAM Mreporter.nih.gov
Modulating Indoleamines to Optimize Immunity in the Setting of Mtb/HIV Co-infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,820,801June 21, 2024April 30, 2029MEHRA, SMRITIreporter.nih.gov
Engineering Yeast towards High Titer Production of Monoterpene Indole Alkaloid Natural ProductsNIHNational Center for Complementary & Integrative Health2021 to 2025$1,819,978July 1, 2018March 31, 2028TANG, YIreporter.nih.gov
IgE Suppressing Berberine Nanomedicine for Treatment of Food AllergiesNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$1,814,418May 11, 2023April 30, 2026YANG, NANreporter.nih.gov
Harnessing the power of p53 with Panaxynol from American Ginseng to suppress colitis and prevent colon cancerNIHNational Cancer Institute2021 to 2024$1,813,414January 1, 2020December 31, 2024HOFSETH, LORNE Jreporter.nih.gov
Guanidinium Toxins as Molecular Probes for NaV StudyNIHNational Institute of General Medical Sciences2021 to 2024$1,805,820September 1, 2016March 31, 2026DU BOIS, JUSTINreporter.nih.gov
600 MHz NMR spectrometer with 1.7mm micro-cryoprobeNIHOffice of the Director, National Institutes of Health2023$1,802,603September 1, 2023August 31, 2025DUGGAN, BRENDAN MICHAELreporter.nih.gov
Lead optimization of a novel cyclic aryl-indole efflux pump inhibitor (EPI) series in combination with levofloxacin against Pseudomonas aeruginosaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,799,789May 1, 2024April 30, 2027PARHI, AJIT Kreporter.nih.gov
Production of Natural Deoxysugars for Use in Chemical Synthesis of GlycosidesNIHNational Institute of General Medical Sciences2023 to 2024$1,798,147March 17, 2022July 31, 2025TURNER, ROBERT J.reporter.nih.gov
Defining the role of isoprenylated xanthones from the mangosteen for enhancing degradation of full length and variant forms of androgen receptor in prostate cancerNIHNational Cancer Institute2021 to 2025$1,796,578January 1, 2019April 30, 2027JOHNSON, JEREMY JAMESreporter.nih.gov
Phase II Clinical trial of GTC in Men on Active SurveillanceNIHNational Cancer Institute2021 to 2024$1,792,639June 1, 2019May 31, 2026KUMAR, NAGI B.reporter.nih.gov
Biomarkers of Sulforaphane/Broccoli Sprout Extract in Prostate CancerNIHNational Cancer Institute2021 to 2023$1,788,361January 1, 2019December 31, 2024SINGH, SHIVENDRAreporter.nih.gov
Connecting specialized metabolism to social cues in actinomycete bacteriaNIHNational Institute of General Medical Sciences2021 to 2025$1,787,304August 1, 2018May 31, 2028TRAXLER, MATTHEW Freporter.nih.gov
Mechanisms and treatment of adolescent phytocannabinoid impairment of prefrontal cortex functionNIHNational Institute on Drug Abuse2022 to 2025$1,784,987May 1, 2022February 28, 2027LU, HUI-CHENreporter.nih.gov
Twist1 as a Target for Prevention and Treatment of Cutaneous Squamous Cell CarcinomaNIHNational Cancer Institute2021 to 2025$1,780,213July 1, 2021December 31, 2026DIGIOVANNI, JOHNreporter.nih.gov
AI-based Mapping of Complex Cannabis Extracts in Pain PathwaysNIHNational Center for Complementary & Integrative Health2023 to 2025$1,776,225February 14, 2023November 30, 2027VRANA, KENT Ereporter.nih.gov
Synthesis of Neurologically Active Small MoleculesNIHNational Institute of General Medical Sciences2021 to 2025$1,773,111September 1, 2017May 31, 2027NEWHOUSE, TIMOTHYreporter.nih.gov
Optical Redox Probe for Continuous Metabolic Monitoring during Natural Products BioprocessingNIHNational Center for Complementary & Integrative Health2022 to 2023$1,772,804December 20, 2019July 31, 2025ZHAO, YOUBOreporter.nih.gov
Therapeutic bubble tea: Preventing the formation of uremic toxins with hydrogel immobilized microbesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$1,772,161January 1, 2022December 31, 2026WINKLER, MARI-KAROLIINAreporter.nih.gov
Enabling synthetic biology through single cell functional genomicsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,766,196February 1, 2022January 31, 2027BURKART, MICHAEL D.reporter.nih.gov
Microbially guided discovery and biosynthesis of biologically active natural productsNIHNational Institute of General Medical Sciences2021 to 2025$1,763,162July 1, 2021April 30, 2027FOX, JEROMEreporter.nih.gov
Synthesis and Study of Medicinally Important MoleculesNIHNational Institute of General Medical Sciences2022 to 2025$1,762,112August 4, 2018July 31, 2028DAI, MINGJIreporter.nih.gov
MegaTrans – human transporter machine learning modelsNIHNational Institute of General Medical Sciences2022 to 2023$1,729,534April 1, 2019August 31, 2025EKINS, SEANreporter.nih.gov
Structural Biology of Complex EnzymesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,723,943February 1, 1990May 31, 2026SMITH, JANET L.reporter.nih.gov
Prevention of paclitaxel-induced peripheral neuropathy with nilotinibNIHNational Cancer Institute2021 to 2023$1,723,403April 17, 2019March 31, 2025HU, SHUIYINGreporter.nih.gov
Botanical Approaches to Combat Metabolic SyndromeNIHNational Center for Complementary & Integrative Health2021 to 2024$1,722,093May 1, 2009April 30, 2026BRANTLEY, PHILLIP Jreporter.nih.gov
Cannabidiol and terpenoid interactions in amygdalar regulation of pain statesNIHNational Center for Complementary & Integrative Health2022 to 2025$1,717,472May 1, 2022January 31, 2027LAND, BENJAMINreporter.nih.gov
Cannabidiol-enhanced cognitive behavioral therapy for generalized anxiety disorderNIHNational Institute of Mental Health2025$1,715,387June 1, 2025May 31, 2027MARUSAK, HILARYreporter.nih.gov
High throughput biosynthesis of ribosomally synthesized and post-translationally modified peptide natural productsNIHNational Institute of General Medical Sciences2021 to 2025$1,714,719July 1, 2021May 31, 2027WALKER, MARK CHALFANTreporter.nih.gov
Islet encapsulation to elicit localized immunosuppression and immune modulation following transplantationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,713,109September 15, 2023July 31, 2028TSE, HUBERT Mreporter.nih.gov
Harnessing light and model endosymbiosis to produce natural productsNIHNational Institute of General Medical Sciences2021 to 2025$1,709,070September 20, 2021June 30, 2027MEHTA, ANGADreporter.nih.gov
Elucidating the mechanisms of cannabinoids on HIV-1 infection and inflammasome activationNIHNational Institute on Drug Abuse2021 to 2024$1,704,831August 1, 2020June 30, 2025SWARTZ, TALIA Hreporter.nih.gov
Role of the Macrophage in Developmentally Programmed NAFLDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,703,451July 1, 2020June 30, 2025FRIEDMAN, JACOB Ereporter.nih.gov
Chemical Synthesis of Bioactive DiterpenoidsNIHNational Institute of General Medical Sciences2022 to 2025$1,702,724September 1, 2022June 30, 2027VANDERWAL, CHRISTOPHER Dreporter.nih.gov
Antitumor AntibioticsNIHNational Cancer Institute2021 to 2024$1,702,340February 1, 1986March 31, 2026BOGER, DALE Lreporter.nih.gov
Carotenoids in VisionNIHNational Eye Institute2021 to 2024$1,698,273August 1, 2011April 30, 2026VON LINTIG, JOHANNES FRIEDRICHreporter.nih.gov
Cannabis use and cardiovascular health outcomes among patients with high blood pressureNIHNational Institute on Drug Abuse2023 to 2025$1,692,524September 15, 2023July 31, 2028ALSHAARAWY, OMAYMA Oreporter.nih.gov
Neuro-immune mechanisms of minor cannabinoids in inflammatory and neuropathic painNIHNational Center for Complementary & Integrative Health2021 to 2023$1,692,291September 15, 2019June 30, 2025HELLMAN, JUDITHreporter.nih.gov
Combinatorial epigenetic-based prevention of breast cancerNIHNational Cancer Institute2021 to 2025$1,689,846April 1, 2014December 31, 2026TOLLEFSBOL, TRYGVE Oreporter.nih.gov
Impact of THC on Extracellular Vesicle SignalingNIHNational Institute on Drug Abuse2021 to 2024$1,685,105June 15, 2020April 30, 2026FOWLER, CHRISTIE Dreporter.nih.gov
Intracellular Stress Inputs to SAPK Signaling PathwaysNIHNational Institute of General Medical Sciences2022 to 2025$1,679,716September 30, 1992May 31, 2026LEVIN, DAVID E.reporter.nih.gov
Glutamatergic plasticity that drives cannabinoid withdrawal and cravingNIHNational Institute on Drug Abuse2023 to 2025$1,674,683September 1, 2023July 31, 2028SPENCER, SADE MONIQUEreporter.nih.gov
Deconvolution of Galbulimima bark pharmacology through chemical synthesis and target assignmentNIHNational Center for Complementary & Integrative Health2023 to 2025$1,661,440June 8, 2023February 28, 2027SHENVI, RYAN ASHOKreporter.nih.gov
New Cooperative Catalysis Concepts for Asymmetric SynthesisNIHNational Institute of General Medical Sciences2021 to 2024$1,661,400June 1, 2020May 31, 2025SCHEIDT, KARL Areporter.nih.gov
A universal droplet microfluidic platform for ultrahigh-throughput biocatalyst evolutionNIHNational Institute of General Medical Sciences2022 to 2023$1,654,892September 25, 2021August 31, 2025PRINCE, ROBINreporter.nih.gov
Exploring the anti-inflammatory properties of cannabis and their relevance to insulin sensitivityNIHNational Institute on Drug Abuse2021 to 2023$1,652,097September 1, 2019May 31, 2026BRYAN, ANGELAreporter.nih.gov
Decoding and targeting saccharopine pathway in cancer metastasisNIHNational Cancer Institute2022 to 2025$1,649,759February 1, 2022January 31, 2027KANG, SUMINreporter.nih.gov
Administrative supplement to promote diversity in health-related research: Melisa GonzalezNIHNational Institute of General Medical Sciences2022 to 2025$1,649,257December 1, 2021November 30, 2026BUTCHER, REBECCA Areporter.nih.gov
Controlled Release Eczema Bandage (CREB)NIHNational Center for Complementary & Integrative Health2024 to 2025$1,626,559August 1, 2025April 15, 2026SINGHAL, AJreporter.nih.gov
Symbiosis and Chemical Diversity GenerationNIHNational Institute of General Medical Sciences2023 to 2025$1,620,154February 1, 2023January 31, 2028SCHMIDT, ERIC Wreporter.nih.gov
Senolytics To slOw Progression of Sepsis (STOP-Sepsis) trialNIHNational Institute on Aging2022 to 2024$1,615,531July 15, 2022June 30, 2025PUSKARICH, MICHAEL A.reporter.nih.gov
Unlocking the biomedical potential of microbial symbionts from complex ecosystemsNIHNational Institute of General Medical Sciences2022 to 2025$1,613,534July 1, 2022April 30, 2027MEVERS, EMILY ELIZABETHreporter.nih.gov
Stimuli-responsive mucin1-specific nanoparticles for efficacious combinatorial chemotherapy of pancreatic ductal adenocarcinomaNIHNational Cancer Institute2022 to 2025$1,611,629August 1, 2022July 31, 2027VIVERO-ESCOTO, JUAN LUISreporter.nih.gov
Investigating (di)terpenoid biosynthesisNIHNational Institute of General Medical Sciences2021 to 2023$1,611,459June 1, 2019November 30, 2024PETERS, REUBEN JOHNreporter.nih.gov
OPTIMIZATION OF NANOPARTICLE TUMOR-LOCALIZATION AND DRUG-LOADINGFOR TREATING MESOTHELIOMANIHNational Cancer Institute2021 to 2023$1,608,570February 1, 2019January 31, 2025GRINSTAFF, MARK W.reporter.nih.gov
Understanding How Nonheme Iron-Dependent Enzymes Assemble Pharmacophores: Studies of Cyclopropane, Aziridine, and Isonitrile FormationNIHNational Institute of General Medical Sciences2021 to 2025$1,604,936June 1, 2018June 30, 2028CHANG, WEI-CHENreporter.nih.gov
Hearing Protection in Cisplatin ChemotherapyNIHNational Institute on Deafness and Other Communication Disorders2022 to 2025$1,600,000February 1, 2022January 31, 2027TAN, XIAODONGreporter.nih.gov
Biosynthesis and Enzymology of Antifungal Natural ProductsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,593,275November 15, 2018October 31, 2024TANG, YIreporter.nih.gov
MUFA-SIRT1 signaling as a central node regulating healthspanNIHNational Institute on Aging2021 to 2024$1,588,424September 15, 2020May 31, 2025MASHEK, DOUGLAS Greporter.nih.gov
Molecular effects of cannabinoids on the Blood Brain Barrier in HIV-infected brainNIHNational Institute on Drug Abuse2024 to 2025$1,588,360August 15, 2024May 31, 2029MARCONDES, MARIA CECILIA GARIBALDIreporter.nih.gov
Determining the Architectures and Activities of Polyketide Synthase ModulesNIHNational Institute of General Medical Sciences2021 to 2025$1,582,712July 1, 2013April 30, 2027KEATINGE-CLAY, ADRIAN TRISTANreporter.nih.gov
Structural Studies of Nonribosomal Peptide SynthesisNIHNational Institute of General Medical Sciences2021 to 2024$1,582,452April 1, 2020March 31, 2026GULICK, ANDREW Mreporter.nih.gov
Investigating mechanisms mediating enhanced THC reinforcement by nicotineNIHNational Institute on Drug Abuse2023 to 2025$1,579,328July 1, 2023May 31, 2028TORREGROSSA, MARY Mreporter.nih.gov
Development of a new marine natural product for the treatment of cryptosporidiosis, an AIDS-defining diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,575,153June 12, 2020May 31, 2026O'CONNOR, ROBERTA Mreporter.nih.gov
Synthetic Macrophage-inducible C-type lectin (Mincle) Agonists: Screening, Design, and Formulation in combination Th17 adjuvantsNIHNational Institute of Allergy and Infectious Diseases2024$1,563,776September 30, 2024September 29, 2029reporter.nih.gov
Biosynthesis of marine terpenoid natural productsNIHNational Institute of General Medical Sciences2023 to 2025$1,561,415August 1, 2023May 31, 2027MOORE, BRADLEY Sreporter.nih.gov
Therapeutic and Mechanistic Evaluation of Cannabis sativa Terpenes in Neuropathic PainNIHNational Center for Complementary & Integrative Health2021 to 2025$1,560,823July 1, 2021April 30, 2027STREICHER, JOHN MICHAELreporter.nih.gov
Cannabinoid modulation of EV composition and function in HIV/SIV infectionNIHNational Institute on Drug Abuse2022 to 2023$1,560,682August 1, 2022July 31, 2025OKEOMA, CHIOMA Mreporter.nih.gov
Natural Product Genome MiningNIHNational Institute of General Medical Sciences2021 to 2024$1,554,961August 1, 2009July 31, 2025MOORE, BRADLEY Sreporter.nih.gov
CB2 Cannabinoid Mechanisms for Suppressing Opioid Tolerance and DependenceNIHNational Institute on Drug Abuse2021 to 2023$1,551,552April 15, 2019February 28, 2026HOHMANN, ANDREA GRACEreporter.nih.gov
Methylotrophs: underexplored bacteria for discovering novel natural products and biochemistryNIHNational Institute of General Medical Sciences2022 to 2025$1,548,728July 1, 2022June 30, 2027PURI, AARON WEBSTERreporter.nih.gov
Chemoproteomic mapping of the ligandable ribonucleoproteome using phloroglucinol meroterpenoidsNIHNational Institute of General Medical Sciences2021 to 2024$1,543,181July 1, 2021December 31, 2024ABBASOV, MIKAIL Ereporter.nih.gov
Discovery and characterization of biocatalysts and metabolites for ribosomally encoded alpha-N-methylated peptide natural productsNIHNational Institute of General Medical Sciences2021 to 2025$1,541,928August 1, 2019April 30, 2030FREEMAN, MICHAEL Freporter.nih.gov
Modeling the effects of chronic marijuana use on neuroinflammation and HIV-related neuronal injuryNIHNational Institute on Drug Abuse2023 to 2025$1,527,736September 30, 2020August 31, 2026MEADE, CHRISTINA Sreporter.nih.gov
Therapeutic small molecule modulation of Kv channelsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,525,426April 1, 2019July 31, 2030ABBOTT, GEOFFREY Wreporter.nih.gov
Mechanistic studies of hirsutinolides and azetidine-based small molecule inhibitors of STAT3NIHNational Cancer Institute2024 to 2025$1,519,343April 1, 2024March 31, 2029TURKSON, JAMES Kreporter.nih.gov
Polyketides via Redox-Triggered Alcohol C-H FunctionalizationNIHNational Institute of General Medical Sciences2021 to 2024$1,515,454May 1, 2011May 31, 2025KRISCHE, MICHAEL Jreporter.nih.gov
Vibrio microcins. A hidden field of targeted anti-cholerae natural products.NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,511,046June 1, 2024April 30, 2029DAVIES, BRYAN WILLIAMreporter.nih.gov
Novel Dearomative Indole Annulation Reactions, Beckmann Fragmentations, and Their Applications to SynthesisNIHNational Institute of General Medical Sciences2022 to 2025$1,502,537September 1, 2022July 31, 2026WU, JIMMYreporter.nih.gov
Posttranslational Modifications during Natural Product BiosynthesisNIHNational Institute of General Medical Sciences2021 to 2025$1,500,616February 1, 1999May 31, 2026VAN DER DONK, WILFRED A.reporter.nih.gov
Electrochemically-Controlled Rapid Chromatographic Separation of Nuisance Compounds from Natural Product ExtractsNIHNational Center for Complementary & Integrative Health2022 to 2023$1,498,000September 19, 2022August 31, 2024SITHARAMAN, BALAJIreporter.nih.gov
New Photocatalytic Coupling Reactions to Prepare Bioactive MoleculesNIHNational Institute of General Medical Sciences2021 to 2024$1,497,816August 1, 2020November 30, 2025MARTIN, DAVIDreporter.nih.gov
Novel antifungal agents against coccidioidomycosisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,496,572July 17, 2024May 31, 2029WALCZAK, MACIEJreporter.nih.gov
Synthesis of Partially Saturated Nitrogen Heterocycles Through Stereo- And Regioselective Dearomatization of HeteroarenesNIHNational Institute of General Medical Sciences2022 to 2025$1,496,033August 15, 2022June 30, 2027KARIMOV, RASHAD RISHADreporter.nih.gov
Identification, characterization, and application of bacterial site-specific vanadium-dependent haloperoxidase enzymesNIHNational Institute of General Medical Sciences2022 to 2025$1,491,048August 1, 2022May 31, 2027MCKINNIE, SHAUN MITCHELL KIRKreporter.nih.gov
Chemical Synthesis and Biology of Complex AlkaloidsNIHNational Institute of General Medical Sciences2021 to 2023$1,490,085April 1, 2020March 31, 2024MAIMONE, THOMAS JOHNreporter.nih.gov
New Methods for the Synthesis of Biologically Active CompoundsNIHNational Institute of General Medical Sciences2023 to 2025$1,489,963June 1, 2023March 31, 2028WOERPEL, KEITH ALLENreporter.nih.gov
Biosensor-driven Platforms for Biosynthesis of Natural Products in BacteriaNIHNational Institute of General Medical Sciences2021 to 2025$1,487,976September 1, 2018November 30, 2028YAN, YAJUNreporter.nih.gov
Identification of Natural Compound Combinations for Prevention of Prostate CancerNIHNational Cancer Institute2021 to 2023$1,485,787February 1, 2019January 31, 2025DIGIOVANNI, JOHNreporter.nih.gov
Bioinformatic Guided Discovery and Characterization of New RiPP Natural ProductsNIHNational Institute of General Medical Sciences2022 to 2025$1,482,563August 1, 2022May 31, 2027CHEKAN, JONATHAN RODIreporter.nih.gov
Define the effects and mechanism of THC and CBD on IFN-I mediated inflammation and immune dysfunction during HIV infectionNIHNational Institute on Drug Abuse2021 to 2024$1,482,000September 30, 2020July 31, 2025ZHEN, ANJIEreporter.nih.gov
Assessing Benefits and Harms of Medical Cannabis and Cannabinoid Use in Breast Cancer Patients During and After TreatmentsNIHNational Cancer Institute2023 to 2025$1,471,480September 20, 2023August 31, 2029HU, JENNIFER Jreporter.nih.gov
Catalytic Processes for Stereoselective Radical Cyclization ReactionsNIHNational Institute of General Medical Sciences2021 to 2024$1,464,433September 1, 2015August 31, 2027ZHANG, X. PETERreporter.nih.gov
Control of Facial Amphiphilicity to Tune Macromolecular Interactions with BacteriaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,460,600December 1, 2019July 31, 2025TANG, CHUANBINGreporter.nih.gov
Defining the impact of cannabinoids on the latent HIV reservoir through multi-omic analysisNIHNational Institute on Drug Abuse2024 to 2025$1,460,156July 1, 2021June 30, 2027BROWNE, EDWARD Preporter.nih.gov
Mechanisms of novel biological nitrogen chemistriesNIHNational Institute of General Medical Sciences2022 to 2025$1,458,552August 1, 2022July 31, 2027CARANTO, JONATHAN Dreporter.nih.gov
Discovery and characterization of a novel natural product for the treatment of both diabetes and obesityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,457,887September 1, 2023June 30, 2027LIU, DONGMINreporter.nih.gov
Discovery, Biosynthesis and Engineering of Side-Chain-Macrocyclic Plant PeptidesNIHNational Institute of General Medical Sciences2022 to 2025$1,451,177July 1, 2022April 30, 2027KERSTEN, ROLAND DAVIDreporter.nih.gov
A Chemoenzymatic Approach to Accessing Novel Isoprenoid ScaffoldsNIHNational Institute of General Medical Sciences2022 to 2025$1,442,826January 1, 2022December 31, 2026SINGH, SHANTERIreporter.nih.gov
Phosphine-Catalyzed Annulations and their ApplicationsNIHNational Institute of General Medical Sciences2021 to 2025$1,430,462May 1, 2006June 30, 2027KWON, OHYUNreporter.nih.gov
Novel nutriceuticals relax airway smooth muscle and decrease inflammation in allergic lung diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,425,021December 1, 2019November 30, 2024EMALA, CHARLES Wreporter.nih.gov
Targeting autophagy to reduce inflammasome-mediated inflammation and immune dysfunction in HIV and methamphetamine useNIHNational Institute on Drug Abuse2024 to 2025$1,416,081June 1, 2024March 31, 2029ZHEN, ANJIEreporter.nih.gov
International Research Training Center for Botanicals and Chronic Diseases in Indonesia, Ecuador and TajikistanNIHFogarty International Center2021 to 2025$1,414,949July 28, 2014May 31, 2030RASKIN, ILYAreporter.nih.gov
Risk and resilience pathways linking community adversity, decision making, and alcohol misuse: A prospective study of Appalachian adolescentsNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2023$1,412,134September 10, 2019June 30, 2025KRISTJANSSON, ALFGEIRreporter.nih.gov
Examining Gut Microbiome as a Determinant of Blueberry Polyphenol Bioavailability to Optimize Dose and Phytochemical Standardization for Functional Effects in HumansNIHNational Center for Complementary & Integrative Health2025$1,407,811September 1, 2025August 31, 2030WEIR, TIFFANY Lreporter.nih.gov
Atom-swapping reaction sequences enabled by decarbonylation and decarboxylationNIHNational Institute of General Medical Sciences2022 to 2025$1,405,931July 5, 2022May 31, 2027LI, JUNQIreporter.nih.gov
Understanding the specificity and non-native catalytic activity of PLP-dependent enzymesNIHNational Institute of General Medical Sciences2023 to 2025$1,405,308August 1, 2023May 31, 2028HAI, YANGreporter.nih.gov
Identification of mechanisms by which cytisine and estrogen inhibit ER stress and exert neuroprotection in Parkinson's diseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,398,086February 15, 2020January 31, 2026SRINIVASAN, RAHULreporter.nih.gov
Studies in the Synthesis of Complex Organic Molecules with Donor-Donor CarbenesNIHNational Institute of General Medical Sciences2023 to 2025$1,397,125September 1, 2023March 31, 2026SHAW, JARED THOMASreporter.nih.gov
3D Printed Calcium Phosphate Scaffolds with Natural Medicinal Compounds for Dental ApplicationsNIHNational Institute of Dental & Craniofacial Research2021 to 2024$1,391,424August 1, 2020July 31, 2026BOSE, SUSMITAreporter.nih.gov
Alkaloid Biosynthetic StudiesNIHNational Institute of General Medical Sciences2021 to 2024$1,390,322August 1, 2021June 30, 2025LIU, PINGHUAreporter.nih.gov
Integrative Model of Metabolomics, Equol and Atherosclerotic cardiovascular disease (IMMEA)NIHNational Heart, Lung, and Blood Institute2024 to 2025$1,385,831September 1, 2024May 31, 2028SEKIKAWA, AKIRAreporter.nih.gov
Optimizing Treatment of Co-occurring Smoking and Unhealthy Alcohol use among PWH in Nairobi, KenyaNIHNational Cancer Institute2024 to 2025$1,382,393September 18, 2024August 31, 2029HIMELHOCH, SETH Sreporter.nih.gov
Discovery and development of drug cocktails evolved by NatureNIHNational Institute of General Medical Sciences2022 to 2025$1,379,650July 1, 2022April 30, 2027ZHU, XUEJUNreporter.nih.gov
Iterative Polyketide Synthase Function, Structure and PathwaysNIHNational Institute of Environmental Health Sciences2021 to 2023$1,374,999February 1, 1978December 31, 2025TOWNSEND, CRAIG ARTHURreporter.nih.gov
Biosynthesis and biological mechanism of minor cannabinoidsNIHNational Center for Complementary & Integrative Health2024 to 2025$1,373,136December 20, 2023October 31, 2028MOORE, BRADLEY Sreporter.nih.gov
Genomics-Accelerated Discovery and Biosynthesis of Phosphonic Acid Natural ProductsNIHNational Institute of General Medical Sciences2021 to 2024$1,369,457September 15, 2020July 31, 2025JU, KOU-SANreporter.nih.gov
EXCITED-STATE CATALYSIS IN ORGANIC SYNTHESISNIHNational Institute of General Medical Sciences2023 to 2025$1,362,969August 5, 2016May 31, 2026NGAI, MING-YUreporter.nih.gov
Advancing the basic science of membrane permeability in macrocyclic peptidesNIHNational Institute of General Medical Sciences2023 to 2025$1,353,856January 1, 2023December 31, 2027LOKEY, ROBERT SCOTTreporter.nih.gov
Deconstructive Molecular Editing Technology Involving C-C Bond ScissionNIHNational Institute of General Medical Sciences2021 to 2024$1,353,593April 1, 2021December 31, 2024KWON, OHYUNreporter.nih.gov
Novel Mechanisms of Catalysis in Natural Product BiosynthesisNIHNational Institute of General Medical Sciences2024 to 2025$1,353,592June 1, 2024May 31, 2029LIU, HUNG-WENreporter.nih.gov
Clinical Trial of Maternal Choline Supplements to Mitigate Effects of Prenatal Cannabis Exposure on Early Brain Development.NIHNational Institute on Drug Abuse2024 to 2025$1,348,364May 1, 2024February 28, 2029HUNTER, SHARON Kreporter.nih.gov
Selective Catalytic Strategies for Carbohydrate SynthesisNIHNational Institute of General Medical Sciences2022 to 2025$1,344,888April 1, 2022January 31, 2026WENDLANDT, ALISONreporter.nih.gov
Repeated Administration of Cannabis Varying in THC and CBD: Effects on Abuse Liability, Experimental Pain and Plasma EndocannabinoidsNIHNational Institute on Drug Abuse2022 to 2023$1,341,614August 15, 2022May 31, 2028HANEY, MARGARETreporter.nih.gov
Effect of Cannabinoids on Tobacco Product Demand and PharmacodynamicsNIHNational Institute on Drug Abuse2024 to 2025$1,337,048May 1, 2024February 28, 2029LEE, DUSTIN CLARKreporter.nih.gov
Health effects of cannabidiol vaping productsNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,323,987March 1, 2024December 31, 2027REBULI, MEGHAN ELIZABETHreporter.nih.gov
Equipment Supplement: Methods and Strategies for the Concise Synthesis of Complex Alkaloid Natural ProductsNIHNational Institute of General Medical Sciences2021 to 2024$1,317,729September 10, 2021August 31, 2025RAWAL, VIRESH H.reporter.nih.gov
Natural Products Research Training in Complementary and Integrative HealthNIHNational Center for Complementary & Integrative Health2021 to 2025$1,315,994December 1, 2019November 30, 2029VAN BREEMEN, RICHARD Breporter.nih.gov
Tissue senescence and age-associated metabolic dysfunction: the role of immune cell mediated inflammationNIHNational Institute on Aging2023 to 2025$1,315,608March 15, 2023December 31, 2027LESNIEWSKI, LISA Areporter.nih.gov
Psychopharmacological effects of cannabidiol on responses to stress and nicotine withdrawalNIHNational Institute on Drug Abuse2024 to 2025$1,303,839September 30, 2010February 28, 2029AL'ABSI, MUSTAFAreporter.nih.gov
Phytotherapy for EndometriosisNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$1,299,643September 1, 2022May 31, 2027AROSH, JOE A.reporter.nih.gov
Defining the complex genetic basis of Plasmodium falciparum resistance to artemisinin and quinine and identifying resistance-refractory therapeuticsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,297,430May 17, 2024March 31, 2029FIDOCK, DAVID Areporter.nih.gov
Mechanisms underlying reversal of cardiac aging by urolithin a treatmentNIHNational Institute on Aging2024 to 2025$1,282,390September 15, 2024August 31, 2029MARCINEK, DAVID J.reporter.nih.gov
Harnessing Polyketide Assembly Lines for Medicinal ChemistryNIHNational Institute of General Medical Sciences2022 to 2025$1,272,120July 1, 2022May 31, 2027KEATINGE-CLAY, ADRIAN TRISTANreporter.nih.gov
Gut Microbiota Underlies the Heterogeneity of Aging Brain's Susceptibility to Postoperative DeliriumNIHNational Institute on Aging2024 to 2025$1,271,798August 1, 2021July 31, 2027SHEN, SHIQIANreporter.nih.gov
Epigallocatechin gallate for prevention of lethal cirrhosis complicationsNIHNational Cancer Institute2023 to 2024$1,270,168September 6, 2023August 31, 2028HOSHIDA, YUJINreporter.nih.gov
Resource Center for Cannabis and Cannabinoid Research (R3CR)NIHNational Center for Complementary & Integrative Health2025$1,260,872April 1, 2025March 31, 2030KHAN, IKHLAS AHMADreporter.nih.gov
Mechanisms of Novel Herbal Therapies for Sepsis.NIHNational Center for Complementary & Integrative Health2021 to 2023$1,256,250September 1, 2010June 30, 2025WANG, HAICHAOreporter.nih.gov
Discovery and characterization of synthetic bioinformatic natural product anticancer agentsNIHNational Cancer Institute2023 to 2025$1,248,263May 1, 2023April 30, 2028BRADY, SEAN Freporter.nih.gov
A Divergent Platform to Chemically Redesign Bioactive 5-8-5 TerpenoidsNIHNational Institute of General Medical Sciences2021 to 2025$1,245,359September 15, 2017December 31, 2026FREDERICH, JAMES H.reporter.nih.gov
Accessing the hidden biosynthetic capabilities of fungiNIHNational Institute of General Medical Sciences2021 to 2023$1,244,288December 15, 2014April 30, 2025KELLER, NANCY Preporter.nih.gov
Impact of Senolytics on Aged Vaccine ResponsesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,244,166November 1, 2022October 31, 2027BARTLEY, JENNAreporter.nih.gov
Mechanisms of Biosynthetic Formation of Deoxy SugarsNIHNational Institute of General Medical Sciences2021 to 2023$1,243,033January 1, 1986May 31, 2025LIU, HUNG-WENreporter.nih.gov
Exploring a New Dimension of Microbial Secondary MetabolismNIHNational Institute of General Medical Sciences2021 to 2024$1,237,932July 5, 2021May 31, 2025SEYEDSAYAMDOST, MOHAMMAD Rreporter.nih.gov
Cellular Senescence in Trisomy 21 lung diseaseNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,236,223September 1, 2024June 30, 2028AL ALAM, DENISEreporter.nih.gov
Research Training in Natural Product Complementary and Integrative HealthNIHNational Center for Complementary & Integrative Health2021 to 2025$1,235,148January 1, 2013July 31, 2029PAULI, GUIDO Freporter.nih.gov
Investigating neofunctionalized alpha-carbonic anhydrases as an emerging class of biosynthetic enzyme in plant and animal metabolismNIHNational Institute of General Medical Sciences2023 to 2025$1,233,380July 1, 2023April 30, 2028NETT, RYAN STEPHANreporter.nih.gov
Discovery and Engineering of Plant Natural Product PathwaysNIHNational Institute of General Medical Sciences2022 to 2025$1,223,671August 1, 2017November 30, 2025SATTELY, ELIZABETH SUSANreporter.nih.gov
Cold triggered Local Anesthesia for Pain ManagementNIHNational Institute of General Medical Sciences2022 to 2025$1,223,651September 1, 2022November 21, 2025ZHAO, CHAOreporter.nih.gov
Genomics Accelerated Natural Product DiscoveryNIHNational Institute of General Medical Sciences2021 to 2024$1,220,277September 15, 2017December 31, 2024MITCHELL, DOUGLAS ALANreporter.nih.gov
Modulation of Protein Biogenesis and Secretion by Natural Product Translocon LigandsNIHNational Institute of General Medical Sciences2021 to 2024$1,219,744April 1, 2019September 30, 2024MCPHAIL, KERRY LEIGHreporter.nih.gov
Synthesis of Complex Terpenes From Simple Precursors: RenewalNIHNational Institute of General Medical Sciences2021 to 2024$1,209,973April 1, 2016March 31, 2025MAIMONE, THOMAS JOHNreporter.nih.gov
Chemical and Molecular Tools for Modulating GPCR FunctionNIHNational Institute of General Medical Sciences2023 to 2025$1,208,259June 1, 2023May 31, 2028OLSON, DAVID Ereporter.nih.gov
Plant terpenoids: Deciphering metabolic pathways and improving production in microbesNIHNational Institute of General Medical Sciences2023 to 2025$1,198,795September 1, 2023June 30, 2028WANG, ZHENreporter.nih.gov
Analgesic efficacy of single and combined minor cannabinoids and terpenesNIHNational Center for Complementary & Integrative Health2021 to 2023$1,188,750September 15, 2019June 30, 2025WARD, SARA Jreporter.nih.gov
Enabling Plant Natural Product Biosynthesis by Debugging Heterologous Protein Expression in YeastNIHNational Institute of General Medical Sciences2021 to 2023$1,187,225August 1, 2019May 31, 2025BLENNER, MARK ALANreporter.nih.gov
Directed Evolution of Isoprenoid BiosynthesisNIHNational Institute of General Medical Sciences2021 to 2024$1,183,677August 1, 2021May 31, 2026WILLIAMS, GAVIN Jreporter.nih.gov
Randomized placebo controlled trial to determine the biological signature of cannabidiol as a treatment for social anxiety disorderNIHNational Center for Complementary & Integrative Health2022 to 2023$1,180,991September 19, 2022February 28, 2026SIMON, NAOMI Mreporter.nih.gov
Targeting Senescence Specific Mechanisms of NF-κB Activation to Reverse Chronic Pulmonary FibrosisNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,178,040May 1, 2024February 28, 2029HAAK, ANDREW JONreporter.nih.gov
Biosynthesis of antifungal nucleoside antibioticsNIHNational Institute of General Medical Sciences2021 to 2023$1,176,963July 1, 2015August 31, 2024YOKOYAMA, KENICHIreporter.nih.gov
Development of Strategies for the Enantioselective Synthesis of Heterocycles and Acyclic AminesNIHNational Institute of General Medical Sciences2022 to 2025$1,171,481July 1, 2022April 30, 2026APONICK, AARONreporter.nih.gov
Biosynthesis of unusual bio-orthogonal functionalities in natural productsNIHNational Institute of General Medical Sciences2021 to 2023$1,164,036July 1, 2020June 30, 2025ZHANG, WENJUNreporter.nih.gov
Antitumor Agents: Structure and SynthesisNIHNational Cancer Institute2021 to 2024$1,163,899June 30, 1976January 31, 2025SMITH, AMOS Breporter.nih.gov
Mechanistic Studies of Lantibiotic Biosynthetic and Tailoring EnzymesNIHNational Institute of General Medical Sciences2021 to 2023$1,161,927February 1, 2006June 30, 2024NAIR, SATISH Kreporter.nih.gov
Development and Exploitation of New Synthetic Strategies for TropolonesNIHNational Institute of General Medical Sciences2021 to 2023$1,155,911May 1, 2015April 30, 2025MURELLI, RYANreporter.nih.gov
Botanical derived progestins and their impact on women's healthNIHNational Center for Complementary & Integrative Health2023 to 2025$1,151,280May 1, 2016February 29, 2028BURDETTE, JOANNA Ereporter.nih.gov
Mechanism of botulinum neurotoxin transport across membranesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,147,915June 1, 2019May 31, 2025BALDWIN, MICHAEL Rreporter.nih.gov
microRNA regulation of NMNAT-mediated Neuroprotection against Peripheral Neuropathy and Chronic PainNIHNational Center for Complementary & Integrative Health2022 to 2023$1,145,822August 16, 2019June 30, 2025ZHAI, RONG GRACEreporter.nih.gov
Optical Control of the Actin CytoskeletonNIHNational Institute of General Medical Sciences2023 to 2025$1,145,446August 1, 2018August 31, 2027TRAUNER, DIRK HARTWIGreporter.nih.gov
Mechanisms of alcohol and menthol dependent pharmaco-neurological interactions with arecoline, an addictive and toxic areca (betel) nut xenobioticNIHNational Institute on Drug Abuse2023 to 2025$1,138,715July 1, 2023May 31, 2028MYERS, ALAN Lreporter.nih.gov
Herbal and Dietary Supplement Induced Liver Injury in the U.S.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,136,701September 30, 2008July 31, 2028HALEGOUA-DEMARZIO, DINAreporter.nih.gov
Resolving the intoxication mechanism of botulinum neurotoxins using single molecule structural biologyNIHNational Institute of General Medical Sciences2023 to 2025$1,134,828September 20, 2023June 30, 2027BOWEN, MARK Ereporter.nih.gov
Impact of quercetin on inflammatory and oxidative stress markers in COPDNIHNational Center for Complementary & Integrative Health2022 to 2024$1,133,111September 9, 2022May 31, 2026SAJJAN, UMADEVI SIVANAPPAreporter.nih.gov
Attacking the Global Problem of Antimicrobial ResistanceNIHNational Eye Institute2021 to 2023$1,131,900January 1, 2005August 31, 2024HAZLETT, LINDA Dreporter.nih.gov
Molecular analysis of bacterial interactionsNIHNational Institute of General Medical Sciences2023 to 2025$1,121,256July 1, 2023April 30, 2028GARG, NEHAreporter.nih.gov
Dearomative Functionalization with ArenophilesNIHNational Institute of General Medical Sciences2021 to 2023$1,116,438July 15, 2017June 30, 2026SARLAH, DAVIDreporter.nih.gov
Age-related Cognitive Changes: Effects of Combined Flavonoid Intake and Physical Exertion Mediated by the Gut MicrobiomeNIHNational Institute on Aging2024 to 2025$1,109,703September 1, 2024April 30, 2030LILA, MARY ANN ANNreporter.nih.gov
Development of a Bacterial Host for Natural Product Discovery and ProductionNIHNational Institute of General Medical Sciences2021 to 2023$1,108,817September 20, 2020June 30, 2025EUSTAQUIO, ALESSANDRA Sreporter.nih.gov
Discovery, biosynthesis and bioactivity of phosphonic acid natural productsNIHNational Institute of General Medical Sciences2021 to 2024$1,103,591April 1, 2018August 31, 2025METCALF, WILLIAM Wreporter.nih.gov
Supplement to Advancing CRISPR-Cas Technologies for the Discovery and Characterization of Novel Fungal Natural ProductsNIHNational Institute of General Medical Sciences2021 to 2023$1,103,196August 1, 2020March 31, 2024GAO, XUEreporter.nih.gov
Lewis Base Ligands Designed to Control Carbon-Carbon Bond FormationNIHNational Institute of General Medical Sciences2023 to 2025$1,102,807August 1, 2023July 31, 2028THOMAS, ANDY ALEXANDERreporter.nih.gov
Synthesis of Bioactive Natural Products and Unnatural CongenersNIHNational Institute of General Medical Sciences2023 to 2025$1,100,985August 1, 2023May 31, 2028SMITH, JOEL MICHAELreporter.nih.gov
Endocannabinoid System Engagement and Clinical Symptom Change with Cannabidiol for Social Anxiety DisorderNIHNational Center for Complementary & Integrative Health2022 to 2023$1,099,216January 18, 2022April 30, 2025TAYLOR, CHARLESreporter.nih.gov
The biosynthesis of N-N bond-containing natural productsNIHNational Institute of General Medical Sciences2021 to 2023$1,093,330January 1, 2020November 30, 2024BALSKUS, EMILY PATRICIAreporter.nih.gov
Investigation of Unusual Cyclization Reactions in BiocatalysisNIHNational Institute of General Medical Sciences2021 to 2023$1,092,447April 1, 1989June 30, 2025LIU, HUNG-WENreporter.nih.gov
Mechanisms of paclitaxel sensitivity and resistanceNIHNational Cancer Institute2024 to 2025$1,089,160March 4, 2024February 28, 2029WEAVER, BETH Areporter.nih.gov
Targeting microtubule stabilization to reduce breast tumor metastasisNIHNational Cancer Institute2021 to 2023$1,086,136September 6, 2012June 30, 2024MARTIN, STUART Sreporter.nih.gov
Signaling mediators of CCL2/CCR2 and natural product discoveryNIHNational Institute of General Medical Sciences2023 to 2025$1,083,333May 1, 2023April 30, 2028WANG, PIWENreporter.nih.gov
CXCR4 as a target for colon cancer chemopreventionNIHNational Cancer Institute2021 to 2023$1,083,245July 1, 2019June 30, 2024BISSONNETTE, BRUCE MARCreporter.nih.gov
Investigating biosynthetic enzymes to enhance natural product discoveryNIHNational Institute of General Medical Sciences2023 to 2025$1,082,531August 5, 2023May 31, 2028HIGGINS, MELANIE ANNreporter.nih.gov
CCAR2 as a Target for Prevention of Colorectal Cancer.NIHNational Cancer Institute2021 to 2023$1,080,815April 1, 2008February 28, 2025DASHWOOD, RODERICK Hreporter.nih.gov
Enzyme Chemistry and Biological Function of RiPP-like ModificationsNIHNational Institute of General Medical Sciences2021 to 2024$1,076,415February 1, 2012December 31, 2024MITCHELL, DOUGLAS ALANreporter.nih.gov
Salivary Protein Influence on Taste and FeedingNIHNational Institute on Deafness and Other Communication Disorders2021 to 2023$1,076,004January 1, 2019December 31, 2024TORREGROSSA, ANN-MARIEreporter.nih.gov
Discovery and Application of New HalogenasesNIHNational Institute of General Medical Sciences2021 to 2023$1,066,740April 1, 2020March 31, 2025CHANG, MICHELLE Creporter.nih.gov
Carbon isotope exchange mediated by vanadium complexesNIHNational Institute of General Medical Sciences2023 to 2025$1,065,309August 1, 2023July 31, 2028BUKHRYAKOV, KONSTANTINreporter.nih.gov
The Role of FoxQ1 in Breast Cancer Chemoprevention by Allium Constituents - R01CA219180NIHNational Cancer Institute2021 to 2023$1,059,662April 1, 2019March 31, 2025SINGH, SHIVENDRAreporter.nih.gov
Defining the impact of cannabinoids on the HIV reservoir in humanized miceNIHNational Institute on Drug Abuse2023 to 2024$1,053,744September 30, 2023July 31, 2025BROWNE, EDWARD Preporter.nih.gov
Therapeutics to prevent aminoglycoside-induced hearing lossNIHNational Institute on Deafness and Other Communication Disorders2024 to 2025$1,048,600July 17, 2020July 31, 2027ZUO, JIANreporter.nih.gov
Applications of Biocatalytic C–H Functionalization in Complex Molecule SynthesisNIHNational Institute of General Medical Sciences2022 to 2025$1,045,595July 1, 2018November 30, 2028RENATA, HANSreporter.nih.gov
Reproductive Medicine Collaborative Consortium: a randomized placebo-controlled trial of EGCG to improve fertility in women with uterine fibroids- Application 4/4NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,034,609September 26, 2019August 31, 2025TAYLOR, HUGH SMITHreporter.nih.gov
Anti-inflammatory Effects of Novel Minor Cannabinoids and Terpenes on Cellular and Murine Models of HIV and HIV ProteinsNIHNational Institute on Drug Abuse2021 to 2023$1,034,538September 30, 2020July 31, 2025PARIS, JASON RICHARDreporter.nih.gov
New Methods for Nitrogen and Oxygen Heterocycle SynthesisNIHNational Institute of General Medical Sciences2021 to 2023$1,029,619July 1, 2006December 31, 2024CHEMLER, SHERRY Rreporter.nih.gov
Multi-omics approaches to lower the barriers to sustainable production of plant natural products with relevance to human healthNIHNational Center for Complementary & Integrative Health2024 to 2025$1,014,698March 1, 2024December 31, 2028BUELL, CAROL ROBINreporter.nih.gov
Prenatal Tobacco and Cannabis Exposure: A Translational StudyNIHNational Institute on Drug Abuse2021 to 2023$999,338September 30, 2018August 31, 2025THANOS, PANAYOTIS Kreporter.nih.gov
Neonatal cerebral vascular injury by prolonged asphyxiaNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$997,190July 1, 2024June 30, 2029PARFENOVA, HELENAreporter.nih.gov
Repurposing Clinical ACT Antimalarials for Experimental Melanoma InterventionNIHNational Cancer Institute2021 to 2023$996,514February 1, 2019January 31, 2025WONDRAK, GEORG Treporter.nih.gov
Method and Strategy Development for the Synthesis of Physiologically Important Natural ProductsNIHNational Institute of General Medical Sciences2021 to 2023$993,113April 1, 2020March 31, 2025WOOD, JOHN Lreporter.nih.gov
The potential of kava in enabling tobacco cessation - its holistic effects in managing stress and insomnia associated with abstinenceNIHNational Center for Complementary & Integrative Health2023 to 2025$984,579August 1, 2023January 31, 2027XING, CHENGGUOreporter.nih.gov
Cannabinoids Modulate Immune Cell-provoked Astrocyte Functions to Suppress HIV-Associated Neuroinflammatory ResponsesNIHNational Institute on Drug Abuse2022 to 2023$976,880August 1, 2018May 31, 2025KAMINSKI, NORBERT Ereporter.nih.gov
Expanding the Metabolic Currencies of LifeNIHNational Institute of General Medical Sciences2024 to 2025$969,365June 1, 2024March 31, 2029LI, HANreporter.nih.gov
Effects of Early-life Cannabinoid Exposure on Prefrontal Circuitry and Cognitive Behavior across DevelopmentNIHNational Institute on Drug Abuse2024 to 2025$967,695June 1, 2024March 31, 2029CHE, ALICIA YUEreporter.nih.gov
Cannabidiol Pharmacotherapy for Comorbid Opioid Addiction and Chronic PainNIHNational Institute on Drug Abuse2021 to 2025$958,500May 1, 2021April 30, 2026DE AQUINO, JOAO PAULOreporter.nih.gov
Cannabis Toxicology in Relation to Neurocognitive Outcomes in AdolescentsNIHNational Institute on Drug Abuse2021 to 2025$956,790March 15, 2021February 28, 2027WADE, NATASHA Ereporter.nih.gov
microRNA regulation of NMNAT-mediated Neuroprotection against Peripheral Neuropathy and Chronic PainNIHNational Center for Complementary & Integrative Health2024$949,953July 10, 2024June 30, 2025ZHAI, RONG GRACEreporter.nih.gov
Directed evolution of broadly fungible biosensorsNIHNational Institute of General Medical Sciences2023 to 2025$943,461January 5, 2023November 30, 2026ELLINGTON, ANDREW Dreporter.nih.gov
Complement in Paclitaxel-induced peripheral neuropathyNIHNational Cancer Institute2021 to 2024$936,532March 5, 2020February 28, 2026XU, JIJUNreporter.nih.gov
3/4, University of Illinois at Chicago Clinical Site- Reproductive Medicine Collaborative Consortium: A randomized placebo-controlled trial of EGCG to improve fertility in women with uterine fibroidsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$934,920September 26, 2019August 31, 2025GONZALEZ, FRANKreporter.nih.gov
The Effects of Cannabidiol on the Driving Performance of Healthy AdultsNIHNational Institute on Drug Abuse2024 to 2025$920,550September 1, 2024May 31, 2029RUDISILL, TONI MARIEreporter.nih.gov
Developing natural compound emodin as a therapy for alcoholic cardiomyopathyNIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2024$918,358March 15, 2023February 28, 2026CARVER, WAYNE Ereporter.nih.gov
Innovation in Catalyst and Oxidative Amination Reaction Development for the Synthesis of Darobactin and Other Ribosomally Synthesized Post-translationally Modified Peptides (RiPPs)NIHNational Institute of General Medical Sciences2021 to 2023$910,532September 20, 2020August 31, 2024BLAKEY, SIMON B.reporter.nih.gov
Exploring the Effects of Cannabinoids on Alcohol Consumption and the Microbiota-Gut-Brain AxisNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$909,791February 1, 2021December 31, 2024KAROLY, HOLLIS Creporter.nih.gov
Cannabinoid inhibition of CNS inflammasome activation via modulation of the gut-brain axisNIHNational Institute on Drug Abuse2025$898,025April 15, 2025February 28, 2030BYRAREDDY, SIDDAPPA Nreporter.nih.gov
Harnessing divergent reactivities of unusual reactive intermediates as platforms to explore high Fsp3 amine chemical spaceNIHNational Institute of General Medical Sciences2024 to 2025$896,558August 1, 2024May 31, 2029SCHOMAKER, JENNIFER MARIEreporter.nih.gov
Excited-State Catalysis in Organic SynthesisNIHNational Institute of General Medical Sciences2021 to 2023$896,285August 5, 2016June 30, 2023NGAI, MING-YUreporter.nih.gov
Investigating the bidirectional relationship between circadian rhythms and cannabinoid useNIHNational Institute on Drug Abuse2024 to 2025$887,766July 15, 2024May 31, 2029KETCHESIN, KYLEreporter.nih.gov
Modular synthesis of antibiotic and anticancer classes of natural productsNIHNational Institute of General Medical Sciences2024 to 2025$887,450August 1, 2023July 31, 2028SEIPLE, IAN BASSreporter.nih.gov
Discovery and Characterization of Manganese-dependent MonooxygenasesNIHNational Institute of General Medical Sciences2024 to 2025$886,587March 15, 2024February 28, 2029RITTLE, JONATHAN Dreporter.nih.gov
Vulnerability and Persistence of Neuroinflammation and Behavioral Deficits from Developmental Cannabinoid ExposureNIHNational Institute on Drug Abuse2024 to 2025$885,374July 1, 2024May 31, 2029WILLETT, KRISTINE Lreporter.nih.gov
Safety, Feasibility and Efficacy of Sulforaphane in Chronic Kidney DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$884,203September 1, 2021June 30, 2025LE, THU H.reporter.nih.gov
Combination of THC and CBD as a Novel Treatment for Co-Occurring Opioid Addiction and Chronic PainNIHNational Institute on Drug Abuse2024 to 2025$883,050May 1, 2024February 28, 2028DE AQUINO, JOAO PAULOreporter.nih.gov
Identification of botanical hHv1 channel blockers as analgesics for neuropathic painNIHNational Center for Complementary & Integrative Health2024 to 2025$873,042June 8, 2023June 30, 2027ZHAO, RUIMINGreporter.nih.gov
Mechanisms of Probiotics in Alcoholic Liver DiseaseNIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2024$854,074September 15, 2015July 31, 2025FENG, WENKEreporter.nih.gov
Development of a phenotypic screening assay for novel compounds that inhibit peripheral pain-sensing neuronsNIHNational Center for Complementary & Integrative Health2023 to 2024$852,338March 17, 2023February 28, 2026CLARKE, WILLIAM Preporter.nih.gov
Synthetic biology to discover kratom natural product biosynthetic pathways for biased analgesic developmentNIHNational Center for Complementary & Integrative Health2024 to 2025$847,954June 6, 2024March 31, 2029LI, SIJINreporter.nih.gov
Chemical biology tools for illuminating cannabinoid signaling pathways in opioid use disorder.NIHNational Institute on Drug Abuse2024 to 2025$842,400August 15, 2024May 31, 2029FRANK, JAMES ALLENreporter.nih.gov
Design, Synthesis, and Evaluation of ant-Glioblastoma AgentsNIHNational Institute of General Medical Sciences2021 to 2023$830,442September 15, 2020June 30, 2025FLOREANCIG, PAUL Ereporter.nih.gov
Natural Phenolic Compounds against Oral Candidiasis (OC)NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$817,417August 9, 2024July 31, 2029MYLONAKIS, ELEFTHERIOSreporter.nih.gov
An Novel Medical System for Quantitative Diagnosis and Personalized Precision Botulinum Neurotoxin Injection in Chronic Pelvic Pain ManagementNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$815,161August 15, 2024September 30, 2027DIAS, NICHOLASreporter.nih.gov
The role of acute excitation of sensory neurons in the development of paclitaxel-induced peripheral neuropathyNIHNational Cancer Institute2024 to 2025$805,748September 1, 2024August 31, 2029YANG, QINGreporter.nih.gov
Gut Microbiota Dysbiosis in Major Depressive Disorder is Associated with Altered Production of Aryl Hydrocarbon Receptor Ligands and Altered Microglia FunctionNIHNational Institute of Mental Health2021 to 2024$804,600September 22, 2021June 30, 2025RAMPERSAUD, RYANreporter.nih.gov
Minor Cannabinoids and Terpenes: Preclinical Evaluation as AnalgesicsNIHNational Center for Complementary & Integrative Health2023 to 2024$797,291September 15, 2019June 30, 2026GAMAGE, THOMAS Freporter.nih.gov
Pathophysiological mechanisms of cannabidiol in stress regulationNIHNational Institute of Mental Health2025$794,696May 1, 2025February 28, 2030BACHI, KERENreporter.nih.gov
Quantifying effects of comorbidities and genetics on cannabinoid exposure in the elderlyNIHNational Institute of General Medical Sciences2022 to 2025$794,611August 1, 2022February 28, 2026ZHOU, ZHUreporter.nih.gov
Hands-on Education and Research for Biomedical and Analytical Learning (HERBAL)NIHNational Center for Complementary & Integrative Health2023 to 2025$788,778July 3, 2023June 30, 2028ROWLEY, DAVID Creporter.nih.gov
Structural Biology of Complex EnzymesNIHNational Institute of General Medical Sciences2025$785,056February 1, 1990August 31, 2027SMITH, JANET L.reporter.nih.gov
Splicing Modulators for Rare Disease IndicationsNIHNational Institute of General Medical Sciences2022 to 2023$782,480September 1, 2022August 31, 2025TAYLOR, RICHARD E.reporter.nih.gov
A novel platform for nonribosomal peptide discoveryNIHNational Institute of General Medical Sciences2025$781,502July 1, 2025June 30, 2028BEHSAZ, BAHARreporter.nih.gov
Cellular mechanisms of astringency transduction and sensationNIHNational Institute on Deafness and Other Communication Disorders2025$780,751August 1, 2025July 31, 2030MOAYEDI-ESFAHANI, YALDAreporter.nih.gov
New Methods and Strategies for the Scalable Synthesis of Complex Bioactive MoleculesNIHNational Institute of General Medical Sciences2024 to 2025$780,000August 1, 2024May 31, 2029ROMITI, FILIPPOreporter.nih.gov
The impact of medical cannabis on pain and inflammation in people living with HIVNIHNational Institute on Drug Abuse2021 to 2024$776,700July 15, 2021February 28, 2026SLAWEK, DEEPIKAreporter.nih.gov
New Methods for Nitrogen and Oxygen Heterocycle SynthesisNIHNational Institute of General Medical Sciences2024 to 2025$773,357July 1, 2024April 30, 2029CHEMLER, SHERRY Rreporter.nih.gov
Dronabinol for the reduction of chronic pain and inflammation in people with sickle cell diseaseNIHNational Heart, Lung, and Blood Institute2022 to 2025$773,104June 1, 2022May 31, 2027CURTIS, SUSANNAreporter.nih.gov
Fetal neuronal extracellular vesicle biomarkers of in-utero effects of maternal cannabinoid use and human fetal brain development and neurobehavioral outcomesNIHNational Institute on Drug Abuse2025$761,367September 1, 2025May 31, 2030GOETZL, LAURAreporter.nih.gov
Computational Exploration of Plant Natural Products Bioactivity and Bioavailability in Human HealthNIHNational Institute of General Medical Sciences2024 to 2025$749,756June 10, 2024April 30, 2029VERMAAS, JOSHUA V.reporter.nih.gov
Development of new methods and strategies for the synthesis of complex moleculesNIHNational Institute of General Medical Sciences2024 to 2025$748,404March 5, 2024January 31, 2029PRONIN, SERGEYreporter.nih.gov
Interrogation of Microbial Natural Product MethyltransferasesNIHNational Institute of General Medical Sciences2021 to 2023$746,999July 15, 2021June 30, 2025DAVIS, TONY D.reporter.nih.gov
Role of Macrophages in CBD mediated attenuation of SEB-induced ARDSNIHNational Institute of General Medical Sciences2023 to 2025$746,874February 1, 2022July 31, 2026WILSON, KIESHAreporter.nih.gov
Development of Mirror-Image Natural Products as Antiarrhythmic TherapeuticsNIHNational Heart, Lung, and Blood Institute2025$744,145September 4, 2025May 31, 2029JOHNSTON, JEFFREY NICHOLASreporter.nih.gov
Biochemistry of membrane proteins involved in lipid and cannabinoid metabolismNIHNational Institute of General Medical Sciences2024 to 2025$743,818August 1, 2024July 31, 2029DAS, ADITIreporter.nih.gov
Predoctoral Training: Innovative Technologies for Natural Products and Integrative Medicine ResearchNIHNational Center for Complementary & Integrative Health2021 to 2025$742,810March 1, 2016March 31, 2027CECH, NADJA Breporter.nih.gov
Discovery of PD-1/PDL-1 inhibitors from marine microbial natural productsNIHNational Cancer Institute2021 to 2024$741,335July 14, 2020June 30, 2025FENICAL, WILLIAMreporter.nih.gov
Understanding and manipulating biosynthetic mechanisms for formation of terpenes relevant to human healthNIHNational Institute of General Medical Sciences2024 to 2025$739,465July 15, 2024May 31, 2029TANTILLO, DEANreporter.nih.gov
Defining the impact of cannabinoids on the HIV reservoir in humanized miceNIHNational Institute on Drug Abuse2025$738,616September 30, 2023July 31, 2028BROWNE, EDWARD Preporter.nih.gov
Mechanistic studies of the menthol receptor TRPM8: a novel target for analgesic drugsNIHNational Center for Complementary & Integrative Health2021 to 2023$738,361September 1, 2019August 31, 2024DIVER, MELINDAreporter.nih.gov
From Genes to Molecules and Back: Expanding the Chemical Space of Microbial and Microbiome Natural ProductsNIHNational Institute of General Medical Sciences2024 to 2025$738,000September 1, 2024August 31, 2029SEYEDSAYAMDOST, MOHAMMAD Rreporter.nih.gov
Development of novel computational protocols to study amyloid oligomerizationNIHNational Institute on Aging2021 to 2025$736,374August 15, 2021July 31, 2027MAN, VIET HOANGreporter.nih.gov
Identification of Biomarkers of Plant-Rich Diets and Carbonyl Stress and Their Associations with Cardiovascular RiskNIHNational Heart, Lung, and Blood Institute2025$733,785September 15, 2025June 30, 2030HU, FRANK Breporter.nih.gov
An LCMS-guided bioanalytical approach for rational natural product library design and optimizationNIHNational Institute of General Medical Sciences2023 to 2025$730,689September 5, 2022June 30, 2027MCCALL, LAURA-ISOBELreporter.nih.gov
Chemical synthesis to access rare heterocycles and tool compounds to probe bacterial polysaccharide metabolismNIHNational Institute of General Medical Sciences2024 to 2025$721,207September 1, 2024June 30, 2029WHITEHEAD, DANIEL CHARLESreporter.nih.gov
A scalable cruciferous vegetable intervention to reduce bladder cancer recurrence and progressionNIHNational Cancer Institute2025$717,150January 1, 2025December 31, 2029YEARY, KAREN HYE-CHEON KIMreporter.nih.gov
Oral THC consumption during adolescence and its impact on adult mouse brainNIHNational Institute on Drug Abuse2025$716,455July 1, 2025March 31, 2030STELLA, NEPHIreporter.nih.gov
Biosynthesis of Unusual Bio-Orthogonal Functionalities in Natural ProductsNIHNational Institute of General Medical Sciences2024 to 2025$716,231April 1, 2024March 31, 2029ZHANG, WENJUNreporter.nih.gov
Influence of microbial metabolites on mitosome function in CryptosporidiumNIHNational Institute of Allergy and Infectious Diseases2025$715,894August 8, 2025July 31, 2030SIBLEY, L. DAVIDreporter.nih.gov
Convergent Evolution in Natural Product BiosynthesisNIHNational Institute of General Medical Sciences2024 to 2025$713,639August 1, 2024May 31, 2029NEWTON, CHRISTOPHERreporter.nih.gov
Bioactive natural product discovery from human oral microbesNIHNational Institute of Dental & Craniofacial Research2024 to 2025$707,318February 16, 2024January 31, 2029ZHANG, WENJUNreporter.nih.gov
Countering microtubule stabilization within hair follicles in ovarian cancer chemotherapyNIHNational Cancer Institute2024 to 2025$702,262April 4, 2024March 31, 2029XU, XIANGXI MIKEreporter.nih.gov
C. officinalis induction of Nrf2 inhibiting type 1 diabetesNIHNational Center for Complementary & Integrative Health2024 to 2025$699,848March 25, 2024December 31, 2028BURKHARDT, BRANT ROGERreporter.nih.gov
Developing ribosome biogenesis inhibitors for the prevention of cancerNIHNational Cancer Institute2024 to 2025$697,000May 21, 2024April 30, 2027BUSZCZAK, MICHAELreporter.nih.gov
Indole Metabolites as Xenobiotic Danger signals in Acute Lung InjuryNIHNational Heart, Lung, and Blood Institute2025$688,163September 1, 2025May 31, 2029EVANKOVICH, JOHN Wreporter.nih.gov
Phase 1 Translational Diabetes Research Using The DYRK1A inhibitor, HarmineNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2023$676,000July 15, 2022June 30, 2024STEWART, ANDREW F.reporter.nih.gov
Cannabidiol as an Adjunct Treatment for Alcohol Withdrawal and CravingNIHNational Institute on Alcohol Abuse and Alcoholism2025$672,377September 20, 2025August 31, 2030WOLINSKY, DAVIDreporter.nih.gov
Characterizing the Epidemiology of Cannabidiol (CBD) Use Among US adultsNIHNational Institute on Drug Abuse2022 to 2025$668,431April 1, 2022March 31, 2027LEAS, ERICreporter.nih.gov
Nautral products for targeting Skp2 in cancer interceptionNIHNational Cancer Institute2024 to 2025$667,250June 1, 2024April 30, 2027ZI, XIAOLINreporter.nih.gov
Discovery of novel natural TEAD inhibitors for the chemoprevention of liver tumorsNIHNational Cancer Institute2024 to 2025$657,145May 14, 2024April 30, 2027CAO, SHUGENGreporter.nih.gov
Expanding Access to Molecular Complexity through Natural Product SynthesisNIHNational Institute of General Medical Sciences2024 to 2025$656,000August 1, 2024May 31, 2029SMITH, MYLES WARWICKreporter.nih.gov
Nanoparticles with Two-Stage Delivery of Tetrodotoxin for Prolonged Duration Local AnesthesiaNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$652,659June 21, 2022May 31, 2024ZHAO, CHAOreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
University of California, San DiegoLa Jolla, CA30$39.3 million0$0
University of California Los AngelesLos Angeles, CA23$34.7 million0$0
University of FloridaGainesville, FL16$32.7 million0$0
University of Colorado DenverAurora, CO19$29.8 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC16$27 million0$0
University of Michigan at Ann ArborAnn Arbor, MI28$26.5 million0$0
Yale UniversityNew Haven, CT15$25.4 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY8$22.8 million0$0
University of Illinois at Urbana-ChampaignUrbana, IL14$22.2 million0$0
Psychogenics, Inc.Paramus, NJ1$21.3 million0$0
Marshall University Research CorporationHuntington, WV1$20.3 million0$0
University of UtahSalt Lake City, UT11$20.2 million0$0
University of MinnesotaMinneapolis, MN14$17.8 million0$0
Johns Hopkins UniversityBaltimore, MD15$17.2 million0$0
University of DelawareNewark, DE3$16.3 million0$0
University of Colorado at BoulderBoulder, CO10$16.1 million0$0
Scripps Research Institute, theLa Jolla, CA8$15.9 million0$0
University of Texas at AustinAustin, TX11$14.2 million0$0
Emory UniversityAtlanta, GA13$14.1 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA16$13.8 million0$0
University of PennsylvaniaPhiladelphia, PA10$13.6 million0$0
University of California-BerkeleyBerkeley, CA13$13.4 million0$0
University of Wisconsin-MadisonMadison, WI9$12.9 million0$0
New York University School of MedicineNew York, NY4$12.4 million0$0
Northwestern University at ChicagoChicago, IL8$12.1 million0$0
University of California, San FranciscoSan Francisco, CA5$11 million0$0
Vanderbilt UniversityNashville, TN10$10.6 million0$0
Duke UniversityDurham, NC3$9.9 million0$0
University of California-IrvineIrvine, CA10$9.5 million0$0
University of Illinois at ChicagoChicago, IL11$9.4 million0$0
Weill Medical Coll of Cornell UnivNew York, NY3$9.4 million0$0
University of ArizonaTucson, AZ3$8.9 million0$0
Boston Children's HospitalBoston, MA3$8.5 million0$0
University of WashingtonSeattle, WA9$8.4 million0$0
Sparian Biosciences, Inc.New York City, NY1$7.9 million0$0
Mayo Clinic RochesterRochester, MN5$7.8 million0$0
Temple Univ of the CommonwealthPhiladelphia, PA5$7.6 million0$0
Massachusetts Institute of TechnologyCambridge, MA4$7.4 million0$0
Stanford UniversityStanford, CA5$7.3 million0$0
Fisher Bioservices, Inc.Rockville, MD1$7.2 million0$0
Northwestern UniversityChicago, IL3$7.2 million0$0
Curza INCSalt Lake City, UT3$6.9 million0$0
North Carolina State UniversityRaleigh, NC5$6.8 million0$0
Purdue UniversityWest Lafayette, IN4$6.8 million0$0
University of California-Santa CruzSanta Cruz, CA3$6.8 million0$0
Trustees of Boston UniversityBoston, MA3$6.7 million0$0
SUNY at BuffaloAmherst, NY6$6.7 million0$0
California Institute of TechnologyPasadena, CA8$6.5 million0$0
University of Texas HLTH Science CenterSan Antonio, TX5$6.1 million0$0
Brigham and Women's HospitalBoston, MA3$6.1 million0$0
Wayne State UniversityDetroit, MI3$6 million0$0
Wake Forest University Health SciencesWinston-Salem, NC4$6 million0$0
Massachusetts General HospitalBoston, MA3$5.7 million0$0
University of ChicagoChicago, IL7$5.7 million0$0
Thomas Jefferson UniversityPhiladelphia, PA2$5.3 million0$0
Oregon Health & Science UniversityPortland, OR4$5.3 million0$0
Vanderbilt University Medical CenterNashville, TN2$5.1 million0$0
Texas Biomedical Research InstituteSan Antonio, TX2$5.1 million0$0
The University of Central Florida Board of TrusteesOrlando, FL3$4.9 million0$0
University of South Carolina at ColumbiaColumbia, SC7$4.9 million0$0
Medical University of South CarolinaCharleston, SC3$4.8 million0$0
Texas A&m University Health Science CTRCollege Station, TX5$4.8 million0$0
Michigan State UniversityEast Lansing, MI5$4.7 million0$0
Indiana University IndianapolisIndianapolis, IN3$4.6 million0$0
University of Miami School of MedicineCoral Gables, FL6$4.6 million0$0
University of Connecticut SCH of Med/dntFarmington, CT2$4.4 million0$0
Boston CollegeChestnut Hill, MA2$4.3 million0$0
University of Oklahoma HLTH Sciences CTROklahoma City, OK3$4.3 million0$0
H. Lee Moffitt Cancer CTR & Res InstTampa, FL2$4 million0$0
Ohio State UniversityColumbus, OH5$4 million0$0
Case Western Reserve UniversityCleveland, OH3$4 million0$0
Oregon State UniversityCorvallis, OR6$3.9 million0$0
Rockefeller UniversityNew York, NY2$3.9 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA2$3.9 million0$0
University of Georgia Research Foundation IncAthens, GA4$3.9 million0$0
Dartmouth CollegeHanover, NH3$3.8 million0$0
University of Texas Med BR GalvestonGalveston, TX2$3.8 million0$0
University of MississippiUniversity, MS4$3.8 million0$0
Georgia Tech Research CorporationAtlanta, GA3$3.7 million0$0
University of Nebraska Medical CenterOmaha, NE4$3.7 million0$0
University of Tennessee Health Sci CTRMemphis, TN3$3.6 million0$0
Texas A&M Engineering Experiment StationCollege Station, TX2$3.6 million0$0
Gilgamesh Pharmaceuticals INCNew York, NY1$3.6 million0$0
Augusta UniversityAugusta, GA3$3.5 million0$0
Virginia Polytechnic Institute and State UniversityBlacksburg, VA4$3.5 million0$0
University of Alabama TuscaloosaTuscaloosa, AL5$3.5 million0$0
Roswell Park Cancer Institute CorpBuffalo, NY2$3.4 million0$0
Iowa State UniversityAmes, IA3$3.4 million0$0
Baylor UniversityWaco, TX3$3.4 million0$0
Georgetown UniversityWashington, DC2$3.4 million0$0
Harvard University D/b/a Harvard School of Public HealthBoston, MA2$3.4 million0$0
University of California at DavisDavis, CA3$3.3 million0$0
Indiana UniversityBloomington, IN2$3.3 million0$0
University of Notre DameNotre Dame, IN2$3.3 million0$0
Battelle Pacific Northwest LaboratoriesRichland, WA1$3.3 million0$0
Florida International UniversityMiami, FL4$3.3 million0$0
William Marsh Rice UniversityHouston, TX5$3.3 million0$0
Mclean HospitalBelmont, MA1$3.2 million0$0
Queen's Medical CenterHonolulu, HI1$3.2 million0$0
Integrated Laboratory Systems, LLCResearch Triangle Park, NC1$3.1 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025492$269,126,5920$0
2024557$286,478,7040$0
2023551$257,088,3300$0
2022395$185,166,5730$0
2021261$130,831,6220$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 6 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 1 award here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)PA-24-175NIHMay 7, 2027Not listedNotice number printed on 1 award here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 1 award here
Limited Competition: NIH Research Evaluation and Commercialization Hubs (REACH) (SB0 Clinical Trial Optional)RFA-OD-27-009NIH93.859November 10, 2026Not listedSame assistance listing 93.859 as 259 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)PAR-27-039NIH93.859January 5, 2027Not listedSame assistance listing 93.859 as 259 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)PAR-27-040NIH93.859January 5, 2027Not listedSame assistance listing 93.859 as 259 awards here
Medical Scientist Training Program (MSTP) (T32)PAR-24-128NIH93.859January 25, 2027Not listedSame assistance listing 93.859 as 259 awards here
Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) Program (UE5/T32)PAR-24-235NIH93.859January 25, 2027Not listedSame assistance listing 93.859 as 259 awards here
Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) Program (UE5/T34)PAR-24-236NIH93.859January 25, 2027Not listedSame assistance listing 93.859 as 259 awards here
National Centers for Cryo-electron Tomography (cryoET) (R24 -Clinical Trial Not Allowed)PAR-26-138NIH93.859January 26, 2027Not listedSame assistance listing 93.859 as 259 awards here
Tribal Institutional Review Board Establishment and Enhancement (TIRBEE) (R24 - Clinical Trial Not Allowed)PAR-24-260NIH93.859January 27, 2027Not listedSame assistance listing 93.859 as 259 awards here
Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)PAR-24-268NIH93.859January 27, 2027$500,000Same assistance listing 93.859 as 259 awards here
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)PA-27-100NIH93.859April 5, 2027Not listedSame assistance listing 93.859 as 259 awards here
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)PA-27-102NIH93.859April 5, 2027Not listedSame assistance listing 93.859 as 259 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185NIH93.859May 7, 2027Not listedSame assistance listing 93.859 as 259 awards here
Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed)PA-24-191NIH93.859May 7, 2027Not listedSame assistance listing 93.859 as 259 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)PA-24-184NIH93.859May 8, 2027Not listedSame assistance listing 93.859 as 259 awards here
IDeA Networks of Biomedical Research Excellence (INBRE)PAR-26-026NIH93.859May 18, 2027Not listedSame assistance listing 93.859 as 259 awards here
Medical Scientist Training Program (MSTP)PAR-27-002NIH93.859May 25, 2027Not listedSame assistance listing 93.859 as 259 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.