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Data / Research funding / Malaria

Malaria: 641 NIH awards ($758.7M) to 178 organizations

641 NIH awards ($758.7M) in the NIH spending category Malaria, to 178 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

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Awards

The 500 largest of 641 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
University of Washington Vaccine and Treatment Evaluation UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$15,173,751December 11, 2019November 30, 2026WALD, ANNAreporter.nih.gov
Kaiser Washington Vaccine and Treatment Evaluation UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$14,173,633December 11, 2019November 30, 2026JACKSON, LISA Areporter.nih.gov
Realizing Effectiveness Across Continents with Hydroxyurea(REACH): A Phase I/II Pilot Study of Hyroxyurea for Children with Sickle Cell AnemiaNIHNational Heart, Lung, and Blood Institute2021 to 2025$6,498,374August 1, 2017July 31, 2027WARE, RUSSELL Ereporter.nih.gov
Biologically informed design of CD8+ T cell-dependent pre-erythrocytic stage malaria vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,330,175February 4, 2021January 31, 2026KAPPE, STEFAN HIreporter.nih.gov
Enhancing immunity to malaria in young children with effective chemopreventionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,263,495July 1, 2025June 30, 2027JAGANNATHAN, PRASANNAreporter.nih.gov
Expanding the breadth, magnitude, and durability of PfSPZ vaccines by creating multi-strain vaccines, designer hybrid and genetically altered parasite vaccines and use of a unique adjuvant.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,933,702April 8, 2021March 31, 2027SIM, B. KIM LEEreporter.nih.gov
Computational models of naturally acquired immunity to falciparum malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$5,666,873April 1, 2020March 31, 2026GREENHOUSE, BRYAN Rreporter.nih.gov
Improving Neonatal health Through Rapid malaria testing in Early Pregnancy with high-sensitivity Diagnostics (INTREPiD)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$5,664,388April 1, 2022March 31, 2027TAYLOR, STEVE MYERreporter.nih.gov
DON in Pediatric Cerebral Malaria: A Phase I / II Dose-Escalation Safety StudyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,567,850June 1, 2025May 31, 2027POSTELS, DOUGLASreporter.nih.gov
Focal mass drug administration (fMDA) to reduce Plasmodium vivax transmission, a pragmatic cluster randomized controlled trial in PeruNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$5,036,878June 1, 2025May 31, 2027HSIANG, MICHELLE SANGreporter.nih.gov
Accelerating discovery of an efficacious Plasmodium vivax multivalent multi-stage vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,835,728December 1, 2020November 30, 2026ADAMS, JOHN Hreporter.nih.gov
Optimal chemopreventive regimens to prevent malaria and improve birth outcomes in UgandaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,809,096April 15, 2020March 31, 2026DORSEY, MATTHEW Greporter.nih.gov
Development of Non-Human Primate Models to Assess Immunological Mechanisms and Antigenic Targets of Protective Sporozoite (SPZ) Vaccines and Establish Superior Efficacy of Next Generation SPZ vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,717,265April 1, 2021March 31, 2027HOFFMAN, STEPHEN LEVreporter.nih.gov
Mechanisms of innate immune dysfunction in SIV/malaria co-infection in pregnancyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$4,672,308September 24, 2021July 31, 2026MANUZAK, JENNIFERreporter.nih.gov
Long-term health and socioeconomic impact of interventions targeting low-density malaria infection (LMI) among children in TanzaniavNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,537,676April 15, 2022March 31, 2027HSIANG, MICHELLE SANGreporter.nih.gov
Structural Analysis and Inhibitor Optimization of Cryptosporidium n-myristoyltransferase for Drug DiscoveryNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,163,372November 15, 2020October 31, 2026STAKER, BART LEEreporter.nih.gov
Integrating human and non-human primate data to understand the acquisition of pre-erythrocytic immunity in the face of previous malaria exposureNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,114,200February 10, 2022January 31, 2027WILDER, BRANDON KEITHreporter.nih.gov
Development of an oral liver-targeted prime-and-trap malaria vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,104,491December 1, 2020November 30, 2026MURPHY, SEAN Creporter.nih.gov
Mosquito SAMSP1 and SAMSP2 influence the initial stage of Plasmodium infection of miceNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,052,693April 14, 2021March 31, 2027FIKRIG, EROLreporter.nih.gov
Defining functional humoral correlates of immunity to guide vaccine designNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,023,233November 24, 2020October 31, 2025BATISTA, FACUNDO DAMIANreporter.nih.gov
A systems immunology approach to evaluate malaria vaccine performance in endemic regions of KenyaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,921,000February 1, 2022January 31, 2027MOORMANN, ANN Mreporter.nih.gov
Selective Plasmodium proteasome inhibitors as novel multi-stage antimalarialsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,856,328September 1, 2019August 31, 2029LIN, GANGreporter.nih.gov
Optimization of novel phenotypic screening hits for treatment of MalariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,843,960April 1, 2021March 31, 2027PHILLIPS, MARGARET A.reporter.nih.gov
Lead Optimization of DHODH Inhibitors for MalariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,721,559January 1, 2013June 30, 2028PHILLIPS, MARGARET A.reporter.nih.gov
Malaria across borders: Measuring imported infections and contributions to local transmission in Uganda and ZimbabweNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,679,817June 16, 2021May 31, 2027RODRÍGUEZ-BARRAQUER, ISABELreporter.nih.gov
Severe Malaria And Risk to The Brain (SMART Brain)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,674,964April 15, 2008January 31, 2029JOHN, CHANDY C.reporter.nih.gov
Optimizing the dose of tafenoquine for the radical cure of Plasmodium vivax malaria in Southeast AsiaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,588,034September 8, 2023August 31, 2028CHU, CINDY Sreporter.nih.gov
Inducing durable, protective immune memory against malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,488,192January 16, 2019December 31, 2023KAPPE, STEFAN HIreporter.nih.gov
Mechanisms of varied sensitivity of P. falciparum field isolates to the antimalarial drug pipelineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,469,861July 1, 2025June 30, 2028ROSENTHAL, PHILIP JONreporter.nih.gov
Evaluating the role of P53 pathways in malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,424,681February 1, 2021January 31, 2027TRAN, TUAN MANHreporter.nih.gov
Chemogenomic Profiling of Plasmodium Falciparum Responses and ResistanceNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,402,300February 10, 2015June 30, 2027ADAMS, JOHN Hreporter.nih.gov
Uncovering the parasite and host determinants of Plasmodium vivax hypnozoite formation and development using single cell sequencing and human liver-chimeric miceNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,399,010February 7, 2022January 31, 2027VAUGHAN, ASHLEY Mreporter.nih.gov
Structure and function of the Plasmodium myosin XIV-actin glideosome.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,384,780May 11, 2017June 30, 2027TRYBUS, KATHLEEN Mreporter.nih.gov
Improving Response to Malaria Outbreaks in Amazon-Basin CountriesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,375,825September 1, 2025August 31, 2026PAN, WILLIAM KUANG-YAOreporter.nih.gov
Innate Immune Activation in MalariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,341,812September 24, 2009February 28, 2025GOLENBOCK, DOUGLAS Treporter.nih.gov
Elucidating the role of TSR glycosylation in Plasmodium parasitesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,339,688June 1, 2020May 31, 2026SWEARINGEN, KRISTIAN EDWARDreporter.nih.gov
Second-Generation Novel Liver Stage Active AntimalarialsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,320,110April 1, 2021March 31, 2027KELLY, JANE Xreporter.nih.gov
Defining the resistome in P. falciparum: evolution and mechanismNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,309,597November 2, 2022October 31, 2027WINZELER, ELIZABETH Areporter.nih.gov
A structured transcriptional switching network that coordinates antigenic variation by malaria parasitesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,290,341September 22, 2021August 31, 2027DEITSCH, KIRK Wreporter.nih.gov
Malaria parasite determinants of host cell tropismNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,286,067July 1, 2022June 30, 2027DURAISINGH, MANOJ Treporter.nih.gov
Once Bitten: Acquisition of Malaria Adaptive Immunity (OBAMA - Immunity)NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,285,014July 1, 2025June 30, 2028PRUDHOMMEOMEARA, WENDYreporter.nih.gov
Treating Brain Swelling in Pediatric Cerebral MalariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,271,417December 12, 2016November 30, 2023TAYLOR, TERRIE ELLENreporter.nih.gov
Pathogenic low affinity CD8 T cells in malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,264,359September 17, 2021August 31, 2026LAMB, TRACEY JANEreporter.nih.gov
Spatial Targeting and Adaptive Vector Control for Residual Transmission and Malaria Elimination in Urban African SettingsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,239,370June 9, 2021May 31, 2027SMITH, DAVID L.reporter.nih.gov
Mechanisms and consequences of extrafollicular B cell activation during malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,235,595September 24, 2021August 31, 2027BUTLER, NOAH SULLIVANreporter.nih.gov
Drivers of strain-specific and strain-transcendent antimalarial immunity in childhoodNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,209,021June 17, 2020May 31, 2026GREENHOUSE, BRYAN Rreporter.nih.gov
Impact of gene-drive systems for population modification on malaria vector mosquitoesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,173,474June 9, 2023May 31, 2026JAMES, ANTHONY A.reporter.nih.gov
The role of γδ T cells in fetal and infant immune defense against malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,151,506March 15, 2011May 31, 2027FEENEY, MARGARET Ereporter.nih.gov
Plasmodium Protein Kinase Focused Antimalarials DiscoveryNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,144,589July 11, 2022June 30, 2027CHAKRABARTI, DEBOPAMreporter.nih.gov
Redefining thermal suitability for urban malaria transmission in the context of humidityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,108,969September 14, 2020August 31, 2027MURDOCK, COURTNEYreporter.nih.gov
Novel Therapeutics to Target Parasite Cytochrome bc1NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,077,845July 15, 2012June 30, 2027RISCOE, MICHAEL KEVINreporter.nih.gov
Molecular basis of antimalarial drug resistance in Plasmodium vivaxNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,064,807March 18, 2022February 28, 2027DURAISINGH, MANOJ Treporter.nih.gov
Systems biological assessment of vaccination-induced protective immunity in African childrenNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,037,984February 1, 2022January 31, 2027PULENDRAN, BALIreporter.nih.gov
Innate Immune Mechanisms Governing Subclinical Malaria in ChildrenNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,030,131September 1, 2022August 31, 2026KAZURA, JAMES WALTERreporter.nih.gov
Novel Antimalarials from FungiNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,025,049May 18, 2020April 30, 2026CHAKRABARTI, DEBOPAMreporter.nih.gov
A Unique Automated Bioreactor for Rearing Aseptic Mosquitoes from Larvae to Adults to Support Manufacture of Sanaria PfSPZ ProductsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,000,000July 18, 2018March 31, 2025BILLINGSLEY, PETER F.reporter.nih.gov
Long Lasting Organic Semiochemical Formulation to Effectively Manage Blood Sucking Diptera.NIHNational Institute of Allergy and Infectious Diseases2022 to 2024$3,000,000July 12, 2017January 31, 2026MAFRA-NETO, AGENORreporter.nih.gov
Cofactor metabolism and mitochondrial function in malaria parasitesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,998,772August 18, 2023July 31, 2027PRIGGE, SEAN TAYLORreporter.nih.gov
A genetically modified Plasmodium falciparum sporozoite vaccine attenuated at the late-liver stageNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,998,001April 21, 2020March 31, 2027SIM, B. KIM LEEreporter.nih.gov
Progressing PfSPZ vaccines for malaria to licensure and commercializationNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,994,338April 14, 2023March 31, 2027HOFFMAN, STEPHEN LEVreporter.nih.gov
Functional investigation of a novel and essential subcellular compartment in Plasmodium falciparum transmission stage parasitesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,972,178March 4, 2022February 28, 2027DVORIN, JEFFREY Dreporter.nih.gov
Optimization of antimalarials targeting multiple life stages of the parasiteNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,967,032August 4, 2021July 31, 2027CARLIER, PAUL Rreporter.nih.gov
Advancing Fast-acting Antimalarials that Disrupt Na+ Homeostasis in ParasitesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,964,364August 12, 2020July 31, 2026VAIDYA, AKHIL Breporter.nih.gov
Pharmacological insights into antimalarial exposure, clinical outcomes, and drug resistance in AfricaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,963,157February 10, 2015April 30, 2026ROSENTHAL, PHILIP JONreporter.nih.gov
Artemisinin Resistance in Africa: its emergence and evolution in RwandaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,954,668August 5, 2021July 31, 2025BAILEY, JEFFREY A.reporter.nih.gov
Determining the interactions between mosquito oogenesis and Plasmodium falciparum survival and transmissionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,950,744June 11, 2020May 9, 2025CATTERUCCIA, FLAMINIAreporter.nih.gov
A glycolipid adjuvant to promote dose sparing, accelerate immunization schedules and extend durability of high-level protection with an attenuated, live sporozoite malaria vaccineNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,935,817July 1, 2016June 30, 2025HOFFMAN, STEPHEN LEVreporter.nih.gov
A universal malaria T cell vaccine based on HLA-E presentationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,934,908May 20, 2022April 30, 2027WILDER, BRANDON KEITHreporter.nih.gov
Phase II STTR development of an intranasal/oral Spirulina-based PfCSP malaria vaccine.NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,925,300May 17, 2018June 30, 2025KHUONG, NHIreporter.nih.gov
Automating mosquito microdissection for a malaria PfSPZ vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,924,306June 20, 2017April 30, 2025HOFFMAN, STEPHEN LEVreporter.nih.gov
Genomic and geospatial analyses of malaria parasite migration to inform eliminationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,915,635March 1, 2020February 28, 2026HARRISON, SHANNON TAKALAreporter.nih.gov
Leveraging PfCRT Structure to Discern Function and Predict Emergence of Drug-Resistant MalariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,908,665July 1, 2019November 30, 2029MANCIA, FILIPPOreporter.nih.gov
The synergistic contributions of EBV and malaria to the etiology of Burkitt lymphomaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,895,508December 12, 2019January 31, 2025SAMAYOA REYES, GABRIELA Mreporter.nih.gov
PreQuine Platform. A novel point of care device for the diagnosis andmonitoring of Glucose-6-Phosphate Dehydrogenase (G6PD)NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,893,164February 8, 2017August 31, 2025HARPER, ROBERTreporter.nih.gov
Malaria transmission blocking through mosquito contact with treated surfacesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,877,675February 4, 2020January 31, 2026CATTERUCCIA, FLAMINIAreporter.nih.gov
Dual artemisinin action combats resistanceNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,862,998March 18, 2021February 28, 2027SULLIVAN, DAVID JOSEPHreporter.nih.gov
Gut microbiota and human malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,860,358July 1, 2020June 30, 2026SCHMIDT, NATHANreporter.nih.gov
Defining targets of protective immunity to vivax malaria using human monoclonal antibodiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,825,320March 24, 2020February 28, 2026KING, CHRISTOPHER Lreporter.nih.gov
Relapsing malaria in Africa: mechanisms for persistence amid falciparum declineNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,825,021July 25, 2022June 30, 2027JULIANO, JONATHAN Jreporter.nih.gov
Importation and transmission of malaria in Zanzibar: a case study for eliminationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,816,019August 1, 2021July 31, 2025JULIANO, JONATHAN Jreporter.nih.gov
Mechanisms of endothelial dysfunction in cerebral malaria and barrier restorative pathwaysNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,808,572September 23, 2020August 31, 2025SMITH, JOSEPH Dreporter.nih.gov
Accelerating Malaria Vaccines with a Custom Preclinical Humanized Mouse Model PlatformNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,803,324March 1, 2022February 28, 2027BATISTA, FACUNDO DAMIANreporter.nih.gov
Developing a multi-component vaccine harnessing potent antibody and cellular responses against the blood-stage of Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,802,178May 1, 2022April 30, 2027SRINIVASAN, PRAKASHreporter.nih.gov
After the flood: Optimal strategies to prevent malaria epidemics caused by severe floodingNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,800,889September 1, 2025August 31, 2028BOYCE, ROSS MATHEWreporter.nih.gov
Discovery of long-acting, chemoprotective antimalarial compoundsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,791,259March 25, 2020February 28, 2026WINZELER, ELIZABETH Areporter.nih.gov
Evaluating the Functional Impact of Genetic Diversity on Malaria Vaccine CandidatesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,788,646August 1, 2025July 31, 2027BEI, AMY KRISTINEreporter.nih.gov
Mapping Drug Resistance Genes in Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,782,422September 1, 2000November 30, 2027ANDERSON, TIM Jreporter.nih.gov
Collective Responses to Malaria VaccinationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,779,001February 9, 2022January 31, 2027STUART, KENNETH Dreporter.nih.gov
Host and parasite factors influencing P. vivax RBC invasion and asexual developmentNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,748,338June 1, 2025May 31, 2027SERRE, DAVIDreporter.nih.gov
Harnessing the Malarial Immunity Omics Landscape in Vaccinated and Unvaccinated Children for Improved Therapeutic StrategiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,743,704July 1, 2025June 30, 2029PERKINS, DOUGLAS JAYreporter.nih.gov
Proline homeostasis: a novel mediator of drug tolerance in Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,742,796April 1, 2020March 31, 2025MAZITSCHEK, RALPHreporter.nih.gov
Defining conserved epitopes on polymorphic malaria antigensNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,726,813February 19, 2021January 31, 2027BUNNIK, EVELIEN MARGARETHAreporter.nih.gov
COVID Transmission and Morbidity in Malawi (COVID-TMM)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,666,340April 1, 2025March 31, 2027VALIM, CLARISSAreporter.nih.gov
Molecular pathways affected by drugs that disrupt Na+ and lipid homeostasis in malaria parasitesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,652,142May 5, 2017December 31, 2027VAIDYA, AKHIL Breporter.nih.gov
Lead optimization and target identification of drugs targeting hypnozoitesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,647,674August 7, 2020July 31, 2025KYLE, DENNIS Ereporter.nih.gov
Resistance of Malaria Parasites to Artemisinin-Based Combination Therapies in UgandaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,627,211August 1, 2008August 31, 2025ROSENTHAL, PHILIP JONreporter.nih.gov
Baseline host and environmental factors that impact pre-erythrocytic malaria vaccine (hypo)responsiveness in endemic regionsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,600,040March 8, 2022February 28, 2027YAZDANBAKHSH, MARIAreporter.nih.gov
Global Research Endeavors to Advance Treatment of Neurological Disorders in Africa (GREAT Neurology)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,561,391May 1, 2021April 30, 2029BIRBECK, GRETCHEN L.reporter.nih.gov
Defining the Role of PfCRT and PfMDR1 as Pleiotropic Mediators of Plasmodium falciparum Multidrug ResistanceNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,538,591August 1, 2001January 31, 2028FIDOCK, DAVID Areporter.nih.gov
Novel Multiple-Stage Active AntimalarialsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,520,964June 14, 2019August 31, 2030KANCHARLA, PAPIREDDYreporter.nih.gov
A GLYCOLIPID ADJUVANT 7DW8-5 FOR MALARIA VACCINESNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$2,501,040September 30, 2023September 29, 2028TSUJI, MORIYAreporter.nih.gov
Malaria associated pathogenesis of chronic kidney disease (MAP-CKD)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,470,944June 1, 2025May 31, 2027CONROY, ANDREA L.reporter.nih.gov
Development of a pre-erythrocytic P. vivax vaccine to prevent clinical relapseNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,467,626January 1, 2019December 31, 2023SATHER, D. NOAHreporter.nih.gov
Impairment of anti-Plasmodium T cell memory by type I Interferon SignalingNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,456,734June 1, 2023May 31, 2028MINKAH, NANA KWAKUreporter.nih.gov
Immunity to Liver-stage malariaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,414,340January 12, 2022January 14, 2025HARTY, JOHN Treporter.nih.gov
Epidemiology and determinants of emerging artemisinin-resistant malaria in EthiopiaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,413,258June 9, 2023May 31, 2028PARR, JONATHAN BOYDreporter.nih.gov
Impact of malaria on shaping immunity to EBV in the etiology of Burkitt lymphomaNIHNational Cancer Institute2021 to 2024$2,374,490July 10, 2014June 30, 2025MOORMANN, ANN Mreporter.nih.gov
Liver resident memory for malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,368,344November 23, 2018October 31, 2024MURPHY, SEAN Creporter.nih.gov
Maturation of human humoral immunity through repeat malaria challengesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,367,571May 24, 2023April 30, 2028WILLIAMSON, KIM Creporter.nih.gov
Rigorous Assessment of P. vivax Relapses and Primaquine Efficacy for Radical CureNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,362,550July 17, 2020June 30, 2026SERRE, DAVIDreporter.nih.gov
Parasite and host cell factors involved in the formation and persistence of Plasmodium vivax hypnozoitesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,358,624February 9, 2023January 31, 2028KAPPE, STEFAN HIreporter.nih.gov
Hijacking Plasmodium ubiquitin-proteasome system to defeat drug resistanceNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,334,364July 1, 2023June 30, 2028LIN, GANGreporter.nih.gov
Elucidating the functions of red blood cell factors in malaria parasite invasionNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,314,537July 1, 2023June 30, 2028EGAN, ELIZABETH S.reporter.nih.gov
Surveillance to track and characterize antimalarial resistance trends in Ugandan Plasmodium falciparum parasites (STARTUP)NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,293,828December 20, 2022November 30, 2025CONRAD, MELISSA Dreporter.nih.gov
Development of next-generation gene drive technologies for Anopheles population engineeringNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,276,593June 1, 2021May 31, 2026BIER, ETHANreporter.nih.gov
A modular platform for infectious disease surveillance at point-of-need.NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,274,286August 7, 2020August 31, 2025FISHER, JAY KENNETHreporter.nih.gov
Defining P. falciparum resistance to artemisinin-based combination therapiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,262,645August 1, 2014February 28, 2027FIDOCK, DAVID Areporter.nih.gov
CD8 T cell mediated disruption of Blood Brain Barrier Tight JunctionsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,226,916July 1, 2017February 28, 2030JOHNSON, AARON Jreporter.nih.gov
MEP pathway resistance in Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,223,785December 1, 2012March 31, 2028ODOM JOHN, AUDREY RAGANreporter.nih.gov
Biogenic amines, malaria and manipulation of mosquito physiology and behavior.NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,184,819August 8, 2022July 31, 2027LUCKHART, SHIRLEYreporter.nih.gov
Defining the mechanism of coma in cerebral malariaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,123,692July 8, 2022June 30, 2027DAILY, JOHANNA PATRICIAreporter.nih.gov
Multi-Omics Characterization of Plasmodium Vivax HypnozoitesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,118,231December 22, 2022November 30, 2027SERRE, DAVIDreporter.nih.gov
Orally Bioavailable 4(1H)-Quinolones with Multi-Stage Antimalarial ActivityNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,114,325April 11, 2019March 31, 2025MANETSCH, ROMANreporter.nih.gov
Genome-wide sieve analysis and immunological validation to identify targets of protective efficacy in field trials of a whole-organism malaria vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,110,841January 15, 2019December 31, 2024CARNEIRO DA SILVA, JOANAreporter.nih.gov
The role of natural killer cells and antibodies in protection from malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,108,688March 25, 2020February 28, 2026HART, GEOFFREY Treporter.nih.gov
Statistical Methods for Efficacy Trials of Vaccines and Monoclonal Antibodies Against Genetically-Diverse PathogensNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,067,031April 1, 2003June 30, 2029GILBERT, PETER B.reporter.nih.gov
Epitope-Based CSP Vaccines Optimized to Achieve Long-Term Sterile ImmunityNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,065,107August 23, 2023July 31, 2027MILICH, DAVID R.reporter.nih.gov
Plasmodium falciparum gametocytogenesis in vitro and in vivoNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,054,301January 8, 2020December 31, 2025WILLIAMSON, KIM Creporter.nih.gov
The Function of Antimalarial Drug Resistance ProteinsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,016,655June 15, 2003October 31, 2026ROEPE, PAUL D.reporter.nih.gov
The evolution of copy number variations in the AT-rich Plasmodium genomeNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,000,646April 1, 2021March 31, 2027GULER, JENNIFER LYNNreporter.nih.gov
Recombinant Outer Membrane Vesicles as a Novel Adjuvant for a Malaria VaccineNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,999,755December 8, 2023November 30, 2026LOCHER, CHRISTOPHERreporter.nih.gov
Manufacture of aseptic, purified, cryopreserved Plasmodium vivax sporozoitesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,995,482April 21, 2016July 31, 2027CHAKRAVARTY, SUMANAreporter.nih.gov
Malarial retinopathy screening system for improved diagnosis of cerebral malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,992,098May 6, 2021April 30, 2024JOSHI, VINAYAK Sreporter.nih.gov
PfSPZ Vaccine for Malaria: Towards a Successful Biologics License Application and CommercializationNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,973,577February 15, 2004June 30, 2023HOFFMAN, STEPHEN LEVreporter.nih.gov
Identifying functional antibody responses that protect against malaria in childrenNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,938,902August 1, 2025July 31, 2027SEYDEL, KARL BOYNTONreporter.nih.gov
Manufacture of aseptic, purified, cryopreserved Plasmodium vivax sporozoitesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,938,759April 21, 2016May 31, 2024CHAKRAVARTY, SUMANAreporter.nih.gov
Perturbations of host cell signaling by a complex hepatotropic pathogenNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,938,593April 1, 2013January 31, 2028KAUSHANSKY, ALEXISreporter.nih.gov
Cryopreservation of Anopheles EmbryosNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,928,928August 1, 2010January 31, 2024BILLINGSLEY, PETER F.reporter.nih.gov
Dissecting the role of EBV and P. falciparum in endemic Burkitt lymphoma pathogenesisNIHNational Cancer Institute2021 to 2023$1,923,862August 14, 2019January 31, 2025LUFTIG, MICAH A.reporter.nih.gov
Defining the immunogenic landscape of early mosquito-stage P. falciparum to accelerate malaria transmission-blocking vaccine discoveryNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,917,896July 5, 2024May 31, 2029SWEARINGEN, KRISTIAN EDWARDreporter.nih.gov
In-Vitro Culture of Plasmodium falciparum Sporozoites for Malaria VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,912,715February 15, 2010May 31, 2025HOFFMAN, STEPHEN LEVreporter.nih.gov
Molecular mechanisms of schizogony in malaria parasitesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,900,856June 1, 2019May 31, 2025DVORIN, JEFFREY Dreporter.nih.gov
Natural Product Inspired Novel Antimalarials with Radical Cure PotentialNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,900,470April 4, 2023March 31, 2028KANCHARLA, PAPIREDDYreporter.nih.gov
Role of Translesional Polymerases in Genome Diversification of the Malaria ParasiteNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,889,240June 10, 2019May 31, 2025KIRKMAN, LAURAreporter.nih.gov
Type-I Interferons drive cell-autonomous immunity to malariaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,887,500June 21, 2022May 31, 2027KURUP, SAMreporter.nih.gov
How to starve a parasite: Manipulating CoA biosynthesis to control Plasmodium development in the mosquitoNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,855,815April 14, 2023March 31, 2027RIEHLE, MICHAEL ALLENreporter.nih.gov
Primaquine metabolism and treatment of P. vivax in MadagascarNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,843,113January 1, 2020September 19, 2023ZIMMERMAN, PETER A.reporter.nih.gov
Virus-like Particle based malaria vaccines targeting vulnerable epitopes in the circumsporozoite proteinNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,841,511November 9, 2022October 31, 2027CHACKERIAN, BRYCE Creporter.nih.gov
Genome-based diagnostics for mapping, monitoring and management of insecticide resistance in major African malaria vectorsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,808,286February 15, 2016May 31, 2027DONNELLY, MARTIN JAMESreporter.nih.gov
Optimizing HIV-malaria treatment in a shifting treatment and resistance landscape in AfricaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$1,796,782December 23, 2010June 30, 2029PARIKH, SUNILreporter.nih.gov
Extent, dynamics and mechanisms of Plasmodium vivax immune evasion caused by PvDBP gene amplificationNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,777,806July 1, 2025June 30, 2028POPOVICI, JEANreporter.nih.gov
Immunological characterization of the P. vivax DBPNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,773,948August 1, 2006March 31, 2026ADAMS, JOHN Hreporter.nih.gov
Essential PK/PD relationships of antimalarial drugsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,753,200February 1, 2012August 31, 2025SHAPIRO, THERESA Areporter.nih.gov
The role of ascorbate in myelopoiesis and infectionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,753,030April 1, 2021July 31, 2026AGATHOCLEOUS, MICHALISreporter.nih.gov
DISCOVERY AND PRECLINICAL DEVELOPMENT OF EFFICACIOUS P. vivax PRE-ERYTHROCYTIC STAGE MALARIA VACCINESNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,745,498November 20, 2020October 31, 2023HERRERA VALENCIA, SOCRATESreporter.nih.gov
Comprehensive characterization of the genetic factors and the host immune response associated to protection from clinical Plasmodium vivax malariaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,744,699March 16, 2023February 29, 2028POPOVICI, JEANreporter.nih.gov
Once bitten: A longitudinal, observational study of successful malaria parasite transmission events between humans and mosquitosNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,739,571July 16, 2019June 30, 2024PRUDHOMMEOMEARA, WENDYreporter.nih.gov
Mitochondrial Functions in Malaria ParasitesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,717,892July 1, 1989October 31, 2028VAIDYA, AKHIL Breporter.nih.gov
ER-shaping proteins of PlasmodiumNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,698,924June 1, 2021May 31, 2027BHANOT, PURNIMAreporter.nih.gov
Harnessing the Unique Biogenesis of the Apicomplexan plastid organelle forAntimalarial TargetsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,687,625June 1, 2019May 31, 2025YEH, ELLENreporter.nih.gov
In vitro modeling of blood brain barrier dysfunction on a chip to elucidate the pathogenesis of cerebral malariaNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,675,237September 15, 2021August 31, 2023GOLIGHTLY, LINNIEreporter.nih.gov
Regulation of Sexual Differentiation in Malaria ParasitesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,670,733June 12, 2019May 31, 2025KAFSACK, BJORN FELIX CAESARreporter.nih.gov
Exposure to Insecticides and Child Growth and Pubertal Development in a South African Population Exposed Through Indoor Residual SprayingNIHNational Institute of Environmental Health Sciences2022 to 2025$1,663,772November 22, 2019October 31, 2026CHEVRIER, JONATHANreporter.nih.gov
Protective role of Neuregulin-1 against cerebral malaria-induced neuronal injury and behavioral sequelaeNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$1,644,196January 1, 2022December 31, 2027STILES, JONATHAN K.reporter.nih.gov
Rationally-Designed, Spontaneous-Particleized Pfs48/45 for a Multivalent Malaria VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,631,717May 20, 2020April 30, 2026LOVELL, JONATHAN Freporter.nih.gov
Molecular basis of effector protein export in the malaria parasite Plasmodium falciparumNIHOffice of the Director, National Institutes of Health2021 to 2024$1,620,000September 10, 2020August 31, 2025HO, CHI-MINreporter.nih.gov
Identification & Evaluation of Novel Malaria Anti-Gametocyte Transmission Blocking Vaccine Candidate AntigensNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,594,902August 29, 2019July 31, 2025NIXON, CHRISTIAN PARCHERreporter.nih.gov
Role of erythrocyte band 3 in malaria adhesionNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,591,509July 10, 1998July 31, 2025CHISHTI, ATHAR H.reporter.nih.gov
Development of a Sustained Release Injectable Formulation for Long-Term Delivery of ELQsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,582,032June 5, 2019May 31, 2024RISCOE, MICHAEL KEVINreporter.nih.gov
Latitudinal Landscape Genomics and Ecology of Anopheles DarlingiNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,580,362June 15, 2014August 31, 2025CONN, JAN Ereporter.nih.gov
Chemical Biology Strategies to Resolve Plasmodium Heat Shock Protein FunctionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,568,340June 1, 2023May 31, 2028DERBYSHIRE, EMILY Rreporter.nih.gov
Exploring Wolbachia for malaria controlNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,567,394February 1, 2024December 31, 2028XI, ZHIYONGreporter.nih.gov
MOLECULAR ANALYSIS OF MALARIA MITOCHONDRIAL GENE REGULATIONNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,564,992January 1, 2022December 31, 2026LANE, KRISTIN Dreporter.nih.gov
Targeting the compromised brain endothelial barrier function during cerebral malaria with AT2 receptor agonistsNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,539,586December 15, 2019November 30, 2024RODRIGUEZ, ANAreporter.nih.gov
Interactions between drug combinations and resistance acquisition risk for antimalarial ATP4 inhibitorsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,532,785June 7, 2024May 31, 2029GUY, RODNEY KIPLINreporter.nih.gov
Role of the Gut Microbiota in Shaping Severity of MalariaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,532,068May 3, 2024April 30, 2029SCHMIDT, NATHANreporter.nih.gov
Evolutionary dynamics of zoonotic malariaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,531,736January 25, 2023June 30, 2025GOLDBERG, AMYreporter.nih.gov
Exploring the etiology of oxidative damage and cell death in placental malariaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,525,553September 20, 2022July 31, 2027MOORE, JULIE Mreporter.nih.gov
Understanding and Targeting Host Processes Essential to Plasmodium InfectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,516,224June 1, 2023May 31, 2028DERBYSHIRE, EMILY Rreporter.nih.gov
Mechanisms of compromised CD8 T cell responses to vaccination in malaria experienced hostsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,507,165June 24, 2024April 30, 2029HARTY, JOHN Treporter.nih.gov
SBIR Topic 109: Development of Monoclonal Antibody- Mediated Interventions to Combat MalariaNIHNational Institute of Allergy and Infectious Diseases2024$1,500,000September 18, 2024September 17, 2027MILLER, JACQUELINEreporter.nih.gov
CRISPR-based Assay for Portable Tropical Infection DiagnosisNIHNational Institute of Allergy and Infectious Diseases2025$1,499,763September 15, 2025September 14, 2028ZHUKOV, DMITRIYreporter.nih.gov
Mobile Health Point-of-Care Diagnostics for MalariaNIHNational Institute of Allergy and Infectious Diseases2021$1,498,121July 19, 2021July 18, 2024PRICE, RHODAreporter.nih.gov
Proteostasis in Plasmodium falciparum artemisinin resistanceNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,493,872January 11, 2024November 30, 2028NG, CAROLINE Lreporter.nih.gov
Mechanisms of environmental sensing and responses by malaria parasitesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,491,706June 1, 2018May 31, 2024DEITSCH, KIRK Wreporter.nih.gov
Population Biology of African Malaria Vectors and ParasitesNIHFogarty International Center2021 to 2025$1,490,400September 29, 2000March 31, 2030YAN, GUIYUNreporter.nih.gov
Elucidating the molecular basis of piperaquine resistance in Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,485,044February 1, 2016November 30, 2027FIDOCK, DAVID Areporter.nih.gov
Data and analysis ecosystem for eukaryotic pathogen targeted sequencingNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,481,893June 21, 2024May 31, 2027GREENHOUSE, BRYAN Rreporter.nih.gov
Epigenetic drivers of quiescence in artemisinin-resistant Plasmodium falciparum malariaNIHNational Institute of Allergy and Infectious Diseases2024$1,480,500September 3, 2024August 31, 2027SMALL-SAUNDERS, JENNIFER L.reporter.nih.gov
Characterization of Ionotropic Receptors in Mating and Blood Feeding in Anopheles mosquitoesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,479,639June 2, 2023May 31, 2028ZWIEBEL, LAURENCE Jreporter.nih.gov
Spatial, temporal, and functional study of the basal complex in Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,475,886March 18, 2024January 31, 2029DVORIN, JEFFREY Dreporter.nih.gov
Nqo2 in Primaquine-Induced Hemolysis of G6PD-deficient RBCsNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,463,166May 15, 2024April 30, 2028GOLDFARB, ADAM N.reporter.nih.gov
From bench to bednet: Developing novel mitochondrial inhibitors for killing Plasmodium in the malaria mosquitoNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,461,927December 18, 2023October 31, 2028CATTERUCCIA, FLAMINIAreporter.nih.gov
Multivalent mRNA-based malaria vaccinesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,456,890August 1, 2024July 31, 2029BURNS, JAMES MATTHEWreporter.nih.gov
Environmental determinants of KSHV transmission in rural UgandaNIHNational Cancer Institute2021 to 2023$1,454,511June 7, 2019July 31, 2024SABOURIN, KATHERINE Rreporter.nih.gov
Exploiting cross-reactive, conserved epitopes in Plasmodium vivax to develop a vaccine against falciparum placental malaria.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,453,074March 10, 2020February 28, 2027YANOW, STEPHANIEreporter.nih.gov
Determinants of apicoplast maintenance in malaria parasitesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,435,500May 20, 2016April 30, 2028PRIGGE, SEAN TAYLORreporter.nih.gov
Structural Vaccinology and Design of Novel Imunogens for Malaria Vaccine DevelopmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,430,568February 1, 2018January 31, 2024GOLDBERG, DANIEL E.reporter.nih.gov
Human-informed data-driven development of next-generation T cell vaccine against malariaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,424,256September 2, 2022August 31, 2026DOOLAN, DENISE L.reporter.nih.gov
Tracking the flow of malaria parasites and drug resistance within the DRC and across its bordersNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,422,383June 21, 2018May 31, 2024BAILEY, JEFFREY A.reporter.nih.gov
RDT-undetectable Malaria in the DR Congo: Epidemiology and Development of AlternativesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,422,114February 22, 2018January 31, 2024JULIANO, JONATHAN Jreporter.nih.gov
Boron-containing antimalarial drug discoveryNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$1,417,295July 8, 2020September 2, 2024BAKER, STEVEreporter.nih.gov
Hit-to-Lead Development of the Kalihinol Scaffold for Malaria TreatmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,406,400September 21, 2018August 31, 2024VANDERWAL, CHRISTOPHER Dreporter.nih.gov
Malaria diagnostic testing and conditional subsidies to target ACTs in the retail sector: the TESTsmART trialNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,404,675September 14, 2018August 31, 2024PRUDHOMMEOMEARA, WENDYreporter.nih.gov
Plasmodium vivax Erythrocyte Invasion Mechanisms and Humoral Immune Response in Duffy Negative AfricansNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,400,309February 9, 2022January 31, 2027LO, EUGENIAreporter.nih.gov
Defining and Exploiting the Circadian Clocks in Malaria ParasitesNIHNational Institute of General Medical Sciences2023$1,399,125September 25, 2023August 31, 2026RIJO-FERREIRA, FILIPAreporter.nih.gov
Regulation of the Immune Response to Plasmodium by IL-10 Producing Natural Killer CellsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,392,951February 8, 2019January 31, 2025HAMILTON HART, SARA ELIZABETHreporter.nih.gov
Training and Research on Severe Malarial AnemiaNIHFogarty International Center2021 to 2025$1,391,750April 22, 2002February 28, 2027PERKINS, DOUGLAS JAYreporter.nih.gov
Noncoding DNA regulatory elements and Anopheles vector biologyNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,390,052February 1, 2020January 31, 2026RIEHLE, MICHELLE Mreporter.nih.gov
Protein glycosylation and trafficking in Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,388,153June 6, 2024April 30, 2029MURALIDHARAN, VASANTreporter.nih.gov
Development and function of CD4+ memory T cells during malariaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,385,505June 15, 2016January 31, 2028BUTLER, NOAH SULLIVANreporter.nih.gov
Regulation of Plasmodium-specific CD4+ T cellsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,385,505September 26, 2016January 31, 2028BUTLER, NOAH SULLIVANreporter.nih.gov
Brain endothelial barrier disruption during cerebral malariaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,381,992May 15, 2024March 31, 2029RODRIGUEZ, ANAreporter.nih.gov
Molecular Mechanisms in Pediatric Cerebral Malaria Pathogenesis and ImmunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,375,854August 1, 2019July 31, 2024SMITH, JOSEPH Dreporter.nih.gov
Functional assays of Plasmodium vivax DBP, EBP, and RBP2b in erythrocyte invasion in Duffy-Negative AfricansNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$1,372,763February 9, 2022October 1, 2023LO, EUGENIAreporter.nih.gov
Dissecting mRNA-ribosome interaction in AU-rich transcriptome of Plasmodium falciparumNIHNational Institute of General Medical Sciences2021 to 2024$1,371,447June 1, 2021March 31, 2025DJURANOVIC, SERGEJreporter.nih.gov
Impacts of Environment, Host Genetics and Antigen Diversity on Malaria Vaccine EfficacyNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,363,169March 1, 2018February 28, 2025BAILEY, JEFFREY A.reporter.nih.gov
Repeat Ivermectin Mass Drug Administrations for MALaria control II (RIMDAMAL II): a double-blind cluster randomized trial for integrated control of malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,352,862August 1, 2018July 31, 2024FOY, BRIAN DAVIDreporter.nih.gov
In vitro modeling of blood brain barrier dysfunction on a chip to elucidate the pathogenesis of cerebral malariaNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,352,800September 15, 2021August 31, 2026GOLIGHTLY, LINNIEreporter.nih.gov
Chromatin structure and control of gene expression in the human malaria parasiteNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,350,090May 2, 2018April 30, 2025LE ROCH, KARINE GAELLEreporter.nih.gov
Deciphering mechanisms of CD4+ T cell-dependent clinical immunity to repeated Plasmodium infectionsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,327,045March 15, 2024January 31, 2029JAGANNATHAN, PRASANNAreporter.nih.gov
ER-shaping proteins of PlasmodiumNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,319,152June 1, 2021May 31, 2023BHANOT, PURNIMAreporter.nih.gov
The genetic basis of emerging multidrug resistance in Plasmodium falciparum African malariaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,318,091March 11, 2024January 31, 2029MOK, SACHELreporter.nih.gov
Defining the complex genetic basis of Plasmodium falciparum resistance to artemisinin and quinine and identifying resistance-refractory therapeuticsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,297,430May 17, 2024March 31, 2029FIDOCK, DAVID Areporter.nih.gov
The mutagenic chain reaction: a method for autocatalyic gene disseminationNIHNational Institute of General Medical Sciences2021 to 2024$1,295,344April 1, 2016March 31, 2025BIER, ETHANreporter.nih.gov
Impact of early childhood malaria prevention on malaria risk at school entry (ERASE)NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,276,157July 10, 2024May 31, 2029HARRISON, SHANNON TAKALAreporter.nih.gov
Inflammatory Suppression of Adaptive Immunity by Plasmodium MIFNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,256,250April 1, 2014April 30, 2025BUCALA, RICHARD Jreporter.nih.gov
Regional Centre for Vector Borne Diseases in West Africa (RCVBD)NIHFogarty International Center2021 to 2025$1,242,000March 16, 2021February 28, 2026AFRANE, YAW ASAREreporter.nih.gov
Malaria and Mosquito/Tick-borne DiseasesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,232,416July 1, 2019July 31, 2030SULLIVAN, DAVID JOSEPHreporter.nih.gov
Repurposing kinase inhibitor chemotypes as antimalarialsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,217,031April 3, 2020March 31, 2026CHIBALE, KELLYreporter.nih.gov
Training in Malaria Epidemiology, Translational Research, and Implementation Science to Strengthen Malaria Policy and Control in UgandaNIHFogarty International Center2021 to 2025$1,187,583June 1, 2017December 31, 2027KAMYA, MOSES ROBERTreporter.nih.gov
Determinants of malaria transmission by submicroscopic gametocytemiaNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,187,247June 22, 2018May 31, 2024LIN, JESSICAreporter.nih.gov
Temporal strain structure and response to interventions in a high endemicity region of Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,178,028July 19, 2019September 1, 2023PASCUAL, MERCEDESreporter.nih.gov
Proton pumping and energy metabolism of the ring stage malaria parasitesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,163,818June 17, 2024April 30, 2029KE, HANGJUNreporter.nih.gov
Malaria variant surface antigen expression and vulnerability to disease in Malian children with Hemoglobin C traitNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,156,266July 15, 2019June 30, 2025TRAVASSOS, MARK Areporter.nih.gov
Cluster randomized trial of intermittent preventive treatment of malaria in school-agechildren to improve the health of students and decrease community transmission(CRITICal)NIHNational Institute of Allergy and Infectious Diseases2025$1,126,029August 7, 2025June 30, 2030DORSEY, MATTHEW Greporter.nih.gov
RAPs-mediated post-transcriptional control in Apicomplexan parasitesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,121,140September 19, 2018August 31, 2025LE ROCH, KARINE GAELLEreporter.nih.gov
Multi-target blood stage vaccine against Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,107,549December 13, 2019November 30, 2026RAJ, DIPAK KUMARreporter.nih.gov
PTEX mechanism in malaria parasite effector protein export and host cell subversionNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,098,864July 1, 2023June 30, 2028BECK, JOSH RYANreporter.nih.gov
The protease network that regulates innate immunity in mosquitoesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,082,384September 13, 2018August 31, 2025MICHEL, KRISTINreporter.nih.gov
Mali-Guinea Research Leadership Training Program for Sustainable control and elimination of Malaria and Neglected tropical diseasesNIHFogarty International Center2021 to 2025$1,068,308June 1, 2010December 31, 2027DOUMBIA, SEYDOUreporter.nih.gov
Optimizing Benefits While Reducing Risks of Iron in Malaria-Endemic AreasNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$1,062,973July 5, 2018May 31, 2024CUSICK, SARAHreporter.nih.gov
Role of TAM receptors in modulating humoral immunity against parasitic infectionsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,041,618September 5, 2024August 31, 2029VIJAY, RAHULreporter.nih.gov
PROTOZOAN PURINE PHOSPHORIBOSYLTRANSFERASES AS TARGETS TO TREAT MALARIA, AFRICAN TRYPANOSOMIASIS AND CHAGAS'S DISEASENIHNational Institute of Allergy and Infectious Diseases2021$1,003,662September 25, 2017August 31, 2023MEEK, THOMASreporter.nih.gov
Malarial Retinopathy Screening System for Improved Diagnosis of Cerebral MalariaNIHNational Institute of Allergy and Infectious Diseases2021$1,000,000June 1, 2014November 30, 2023JOSHI, VINAYAK Sreporter.nih.gov
PfSPZ Vaccine for Prevention of Plasmodium falciparum malariaNIHNational Institute of Allergy and Infectious Diseases2022$988,772September 1, 2022June 30, 2024HOFFMAN, STEPHEN LEVreporter.nih.gov
Novel Plasmodial Surface Anion Channel Inhibitors as Antimalarial DrugsNIHNational Institute of Allergy and Infectious Diseases2021$982,478September 21, 2012May 31, 2023BUTLER, MICHELLE M.reporter.nih.gov
Training in Malaria Research in MyanmarNIHFogarty International Center2021 to 2025$978,258March 15, 2021February 28, 2027CUI, LIWANGreporter.nih.gov
Mentoring translational scientists in international infectious disease researchNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$969,511January 22, 2019December 31, 2028GREENHOUSE, BRYAN Rreporter.nih.gov
An MRI Ancillary Study of Malaria Fever Control RCTNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$969,288March 15, 2020April 30, 2025BIRBECK, GRETCHEN L.reporter.nih.gov
Preparing for a world with artemisinin resistance: using individual-based epidemiological modeling to minimize the long-term detrimental effects of antimalarial drug resistanceNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$966,314August 10, 2020December 31, 2023BONI, MACIEJ Freporter.nih.gov
Predicting Epilepsy in Cerebral Malaria: Working Toward Identifying Biomarkers of Epileptogenesis in ChildrenNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$961,585September 1, 2021December 31, 2025PATEL, ARCHANA A.reporter.nih.gov
Elucidating the trafficking mechanisms of effector proteins to the Plasmodium infected red blood cellNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$935,451January 11, 2022December 31, 2023MURALIDHARAN, VASANTreporter.nih.gov
Mapping Drug Resistance Genes in Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2021$923,047September 1, 2000November 30, 2022ANDERSON, TIM Jreporter.nih.gov
Essential functions of the mitochondrion in malaria parasitesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$921,732August 20, 2024July 31, 2029RAJARAM, KRITHIKAreporter.nih.gov
Elucidating the mechanism for malaria rhythmicity: an underlying circadian clock of the parasiteNIHNational Institute of General Medical Sciences2022 to 2024$894,503September 18, 2019April 30, 2026RIJO-FERREIRA, FILIPAreporter.nih.gov
Mentoring in Translational Malaria GenomicsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$868,031January 12, 2018December 31, 2027JULIANO, JONATHAN Jreporter.nih.gov
Serological markers of natural immunity to Plasmodium falciparum infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$858,047July 12, 2021January 23, 2026FRIEDMAN-KLABANOFF, DEANNAreporter.nih.gov
Geo-enabled detect and respond system for antimalarial resistance in Ghana: GDRS - GhanaNIHFogarty International Center2023 to 2025$853,846February 23, 2024May 31, 2027ABIMIKU, ALASH'LE G.reporter.nih.gov
Species-transcending prevention of mosquito vector infectionNIHNational Institute of Allergy and Infectious Diseases2025$832,071November 14, 2024October 31, 2029SATHER, D. NOAHreporter.nih.gov
Rapid, Point of Care Diagnostic for Malaria, highly sensitive for P. vivax, with species differentiationNIHNational Institute of Allergy and Infectious Diseases2021$827,800August 6, 2020July 31, 2022GALEN, PETERreporter.nih.gov
mRNA-LNP vaccines targeting multiple stages and multiple species of human malaria parasiteNIHNational Institute of Allergy and Infectious Diseases2025$813,160December 26, 2024November 30, 2029KUMAR, NIRBHAYreporter.nih.gov
The function of atypical B cells in the immune response against malariaNIHNational Institute of Allergy and Infectious Diseases2025$812,704January 3, 2025December 31, 2026BUNNIK, EVELIEN MARGARETHAreporter.nih.gov
Potent Antibody Protection Against P. falciparum and P. vivax MalariaNIHNational Institute of Allergy and Infectious Diseases2025$807,330August 12, 2025July 31, 2030DEKOSKY, BRANDON JAMESreporter.nih.gov
Targeting mosquito complement to alter the specificity of the innate immune responseNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$805,000May 4, 2018April 30, 2024POVELONES, MICHAEL JOSEPHreporter.nih.gov
Improving the accuracy of malaria surveillance with serology and parasite genetic dataNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$799,646December 8, 2021November 30, 2026BRIGGS, JESSICAreporter.nih.gov
Kinase Targeted Antimalarial AgentsNIHNational Institute of Allergy and Infectious Diseases2021$798,586December 16, 2019November 30, 2022ZUTSHI, REENAreporter.nih.gov
Functional analysis of epigenetic regulators of malaria blood-stage proliferation and transmissionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$797,500February 20, 2018April 30, 2023DURAISINGH, MANOJ Treporter.nih.gov
Elucidating ligand-receptor interactions required for Plasmodium vivax blood-stage infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$797,500July 1, 2018December 31, 2023DURAISINGH, MANOJ Treporter.nih.gov
Deciphering the Role of Non-Coding RNAs in Gene RegulationNIHNational Institute of Allergy and Infectious Diseases2025$791,864December 1, 2024November 30, 2029LE ROCH, KARINE GAELLEreporter.nih.gov
Innate-adaptive immune bridging in gravidity-dependent immunity against placental malaria: a multi-omics approachNIHNational Institute of Allergy and Infectious Diseases2025$789,442July 17, 2025June 30, 2030JAGANNATHAN, PRASANNAreporter.nih.gov
A systems analysis to understand the differential pharmacokinetics and protective efficacy of anti-malarial monoclonal antibodies in field trials.NIHNational Institute of Allergy and Infectious Diseases2025$781,241August 5, 2025July 31, 2030TRAN, TUAN MANHreporter.nih.gov
Genomic surveillance for artemisinin resistance in Africa: moving beyond a candidate gene approachNIHNational Institute of Allergy and Infectious Diseases2025$776,905December 1, 2024November 30, 2029HARRISON, SHANNON TAKALAreporter.nih.gov
tRNA modification reprogramming in artemisinin-resistant Plasmodium falciparum: An epigenetic driver of resistance?NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$768,864September 1, 2021August 31, 2025SMALL-SAUNDERS, JENNIFER L.reporter.nih.gov
Optimization of antimalarials targeting multiple life stages of the parasiteNIHNational Institute of Allergy and Infectious Diseases2021$768,193August 4, 2021July 31, 2026CARLIER, PAUL Rreporter.nih.gov
Plasmepsin X function in PlasmodiumNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$762,500January 2, 2018December 31, 2023GOLDBERG, DANIEL E.reporter.nih.gov
Mentoring in patient-oriented research in global healthNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$759,276January 11, 2016July 31, 2027LAUFER, MIRIAM K.reporter.nih.gov
Target-specific antimalarial compound identification using phenotypic assaysNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$753,000June 3, 2019May 31, 2024NILES, JACQUIN Creporter.nih.gov
Automated Mobile Microscopy for Malaria Diagnosis and surveillance in UgandaNIHNational Institute of Biomedical Imaging and Bioengineering2023 to 2025$751,421September 18, 2023July 31, 2026NAKASI, ROSEreporter.nih.gov
Examining the mechanisms and optimization of malaria chemoprevention strategies to improve birth outcomes in AfricaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$743,488July 1, 2025June 30, 2028ROH, MICHELLEreporter.nih.gov
Discovery of Antimalarials with Novel Mechanism of ActionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$740,914January 1, 2018December 31, 2023CHAKRABARTI, DEBOPAMreporter.nih.gov
Malaria Management through an On-demand Diagnostic Approach using Novel Ionic ProbesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$735,349May 15, 2019April 30, 2025BADU-TAWIAH, ABRAHAMreporter.nih.gov
Identifying the targets of protective immunity to severe falciparum malariaNIHNational Institute of Allergy and Infectious Diseases2025$708,202December 20, 2024November 30, 2029KURTIS, JONATHAN D.reporter.nih.gov
Chemosensory Mechanisms Driving Malaria TransmissionNIHNational Institute of Allergy and Infectious Diseases2025$707,696November 15, 2024October 31, 2029MCMENIMAN, CONOR JAMESreporter.nih.gov
Malaria vaccine evaluation in a novel infant NHP challenge modelNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$706,000November 4, 2022October 31, 2025SHEARS, MELANIE JANETreporter.nih.gov
Understanding Emerging artemisinin partner drug resistance in eastern AfricaNIHNational Institute of Allergy and Infectious Diseases2025$705,896August 12, 2025July 31, 2030FERDIG, MICHAEL Treporter.nih.gov
The Malaria Transfusion Risk (MATRix) StudyNIHNational Heart, Lung, and Blood Institute2021 to 2024$705,384May 3, 2020April 30, 2026BLOCH, EVAN MARTINreporter.nih.gov
Predicting the spread of antimalarial drug resistance using deep learning surrogatesNIHNational Institute of Allergy and Infectious Diseases2025$703,807September 25, 2025August 31, 2030JULIANO, JONATHAN Jreporter.nih.gov
Discovery and preclinical evaluation of Plasmodium falciparum and P. vivax coiled coil antigens for malaria vaccine developmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$702,029January 3, 2020December 31, 2022HERRERA VALENCIA, SOCRATESreporter.nih.gov
Phenotype-based Screens to Identify Genetic Factors Associated with Gametocyte Development in Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2025$700,288November 12, 2024October 31, 2029ADAMS, JOHN Hreporter.nih.gov
Plasmodium and Anopheles midgut interactive proteins influence malaria transmissionNIHNational Institute of Allergy and Infectious Diseases2025$699,814November 20, 2024October 31, 2029LI, JUNreporter.nih.gov
Evolution and coevolution of invasive Anopheles stephensi and sympatric Plasmodium populations in Africa: A genomic investigationNIHNational Institute of Allergy and Infectious Diseases2025$695,801September 17, 2025August 31, 2026CARTER, TAMARreporter.nih.gov
Novel Genetic Mechanism of Artemisinin Resistance for MalariaNIHNational Institute of Allergy and Infectious Diseases2021$694,949April 5, 2013June 30, 2023WIRTH, DYANN Freporter.nih.gov
Exploring the roles of acquired immunity and functional constraint in sculpting malaria antigenic diversity in a longitudinal cohortNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$694,822September 25, 2018October 31, 2024NEAFSEY, DANIEL Ereporter.nih.gov
Determinants of poor responsiveness to the booster dose of the RTS,S malaria vaccine in African childrenNIHNational Institute of Allergy and Infectious Diseases2025$690,500December 6, 2024November 30, 2029VALIM, CLARISSAreporter.nih.gov
Next Generation ELQs for Treatment and Once-Monthly Protection Against MalariaNIHNational Institute of Allergy and Infectious Diseases2024$686,895September 2, 2024April 30, 2025RISCOE, MICHAEL KEVINreporter.nih.gov
Impact of early-life pathogen exposures on pre-erythrocytic malaria vaccine effectiveness in Kenyan infantsNIHNational Institute of Allergy and Infectious Diseases2025$682,200August 22, 2025July 31, 2030DOBBS, KATHERINE ROSEreporter.nih.gov
Neutrophil-driven mucosal dysfunction in SIV/malaria co-infectionNIHOffice of the Director, National Institutes of Health2021 to 2022$680,000April 1, 2021January 31, 2023MANUZAK, JENNIFERreporter.nih.gov
Sickle Cell Anemia, Splenic Pathology, and Hydroxyurea in Sub-Saharan AfricaNIHNational Heart, Lung, and Blood Institute2021 to 2024$678,240July 21, 2020June 30, 2025SMART, LUKEreporter.nih.gov
Characterizing the interaction between human and vector behaviors to enhance the impact of malaria control interventions in UgandaNIHNational Institute of Allergy and Infectious Diseases2025$675,962August 11, 2025July 31, 2030KREZANOSKI, PAUL JOSEPHreporter.nih.gov
Emerging zoonotic malaria in Malaysia: strengthening surveillance and evaluating population genetic structure to improve regional risk prediction toolsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$674,176September 1, 2021August 31, 2026RAJAHRAM, GIRIreporter.nih.gov
The age-specific impact of seasonal malaria chemoprevention on malaria incidence, antibody responses, and parasite reservoirs in Malian childrenNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$672,338April 23, 2021March 31, 2027COULIBALY, DRISSAreporter.nih.gov
Red blood cell modifiers for Plasmodium falciparum growth in sickle cell disease erythrocytesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$671,760August 1, 2020April 30, 2025ARCHER, NATASHA MARIE BERNADETTEreporter.nih.gov
Tfh responses to novel vaccine candidates and protection from pediatric falciparum malariaNIHNational Institute of Allergy and Infectious Diseases2021$668,302August 11, 2017July 31, 2023KURTIS, JONATHAN D.reporter.nih.gov
Memory Regulatory T cells in Recurring MalariaNIHNational Institute of Allergy and Infectious Diseases2025$650,020August 1, 2025July 31, 2030KURUP, SAMreporter.nih.gov
Mosquito extracellular vesicles in malaria parasite killing and immune primingNIHNational Institute of Allergy and Infectious Diseases2025$648,924February 24, 2025January 31, 2030SMITH, RYAN C.reporter.nih.gov
Regulation of brain endothelial integrity by angiotensin receptors as treatment for cerebral malariaNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$646,503June 1, 2018February 29, 2024RODRIGUEZ, ANAreporter.nih.gov
Discovering the essential genome of Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2021$643,737June 15, 2018May 31, 2024ADAMS, JOHN Hreporter.nih.gov
Integrative Multiomics to Probe Interactions of the Gut Microbiome with Malaria Pathogenesis and Antimalarial Pharmacokinetics in HumansNIHNational Institute of Allergy and Infectious Diseases2025$636,193August 25, 2025July 31, 2030IPPOLITO, MATTHEW MICHAELreporter.nih.gov
Function of PfNCR1 at the PPM/PVM InterfaceNIHNational Institute of Allergy and Infectious Diseases2025$633,218July 17, 2025June 30, 2030GOLDBERG, DANIEL E.reporter.nih.gov
Toward field-ready paratransgenesis for malaria: bacterial strain optimization and microbiota interactionsNIHNational Institute of Allergy and Infectious Diseases2025$606,815April 18, 2025March 31, 2030LAMPE, DAVID Jreporter.nih.gov
Enhancing T and B cell responses to Plasmodium infection and vaccination via IL-15NIHNational Institute of Allergy and Infectious Diseases2024$606,767June 20, 2024April 30, 2025BURRACK, KRISTINA STOERMERreporter.nih.gov
Aggressive Antipyretics in CNS Malaria: A Randomized-Controlled Trial Assessing Antipyretic Efficacy and Parasite ClearanceNIHNational Institute of Neurological Disorders and Stroke2021$602,537September 15, 2017May 31, 2023BIRBECK, GRETCHEN L.reporter.nih.gov
Attenuation of Liquid Formulation for PfSPZ Vaccine by X-RayNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$600,000April 12, 2021March 31, 2024JAMES, ERIC ROBERTreporter.nih.gov
In vitro bioreactor production of a genetically modified late liver stage-arresting replication competent Plasmodium falciparum sporozoite vaccineNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$600,000June 3, 2022May 31, 2025SIM, B. KIM LEEreporter.nih.gov
Epitope-directed monoclonal antibody production for mosquito immune cells (for malaria)NIHNational Institute of Allergy and Infectious Diseases2023$599,993September 1, 2023August 31, 2025YU, YANGreporter.nih.gov
Conditional male lethal Anopheles stephensi line for the efficient manufacture of malaria vaccinesNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$599,951February 14, 2023January 31, 2025BILLINGSLEY, PETER F.reporter.nih.gov
Delivery of a candidate AgTRIOVx malaria vaccine by thermostable microneedle patchesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$599,740June 1, 2024May 31, 2027ANTHONY, KAREN G.reporter.nih.gov
Spatial repellents to reduce the outdoor transmission of malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$599,147January 1, 2021June 30, 2025CHEN, INGRID TING-TINGreporter.nih.gov
The Development and Function of Plasmodium-specific memory B cellsNIHNational Institute of Allergy and Infectious Diseases2021$596,609December 16, 2016November 30, 2022PEPPER, MARIONreporter.nih.gov
Identifying gaps between LLIN use and vector exposure to improve malaria controlNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$591,145July 1, 2019December 31, 2024KREZANOSKI, PAUL JOSEPHreporter.nih.gov
An instrument-free malaria diagnosticNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$588,900June 1, 2024May 31, 2026TOBIN, GREGORY JOHNreporter.nih.gov
Next Generation ELQs for Treatment and Once-Monthly Protection Against MalariaNIHNational Institute of Allergy and Infectious Diseases2025$587,318May 1, 2025April 30, 2029RISCOE, MICHAEL KEVINreporter.nih.gov
Memory T follicular helper cell kinetics and localization during recall immune responses to tetanus vaccinationNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$586,904August 12, 2019July 31, 2024FROSCH, ANNE ELIZABETH PARKERreporter.nih.gov
Impact of gestational SARS-CoV-2 and maternal inflammation on child growth and neurodevelopment in a malaria-endemic settingNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$579,960September 1, 2023August 31, 2028JACOBSON, KAREN BLAKEreporter.nih.gov
Genetic and social network analysis to target interventions for malaria eliminationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$579,756July 22, 2020June 30, 2025SMITH, JENNIFER LINNEAreporter.nih.gov
Kruppel-Like Factor 2 Counters Vascular and Immunologic Dysfunction in Child Cerebral MalariaNIHNational Institute of Allergy and Infectious Diseases2021$576,496February 15, 2017January 31, 2023KAZURA, JAMES WALTERreporter.nih.gov
Mentoring Translational Researchers for Careers in Pediatric Global HealthNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$574,659June 3, 2014June 30, 2025FEENEY, MARGARET Ereporter.nih.gov
Clinical Pharmacology of Malaria Control and Elimination: Pharmacodynamics ofArtemisinin-based Combination Agents and their Barriers to Drug ResistanceNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$574,240February 13, 2020January 31, 2025IPPOLITO, MATTHEW MICHAELreporter.nih.gov
Placental malaria: The role of inflammation at the maternal-fetal interfaceNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$569,958December 4, 2018November 30, 2023GAW, STEPHANIE LINAreporter.nih.gov
Serial Killers to Mosquitos: The Spatial Targeting of Larval habitats in rural Uganda using geographic ProfilingNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$564,641December 1, 2018November 30, 2024BOYCE, ROSS MATHEWreporter.nih.gov
The Germinal Center and T cell help in Three Phases of Clearance of PlasmodiumNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$564,054November 1, 2017July 15, 2022STEPHENS, ROBINreporter.nih.gov
Modularizing manufacture of PfSPZ vaccines: ookinete production for PfSPZ manufacture in mosquitoes and in vitroNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$559,942September 6, 2023August 31, 2025HOFFMAN, STEPHEN LEVreporter.nih.gov
Directed in vivo assembly of a robust biopolymer particle-based multistage malaria vaccineNIHNational Institute of Allergy and Infectious Diseases2025$549,032September 10, 2025August 31, 2028REHM, BERNDreporter.nih.gov
Discovering the Essential Genome of Plasmodium FalciparumNIHNational Institute of Allergy and Infectious Diseases2024$543,940June 15, 2018June 30, 2026ADAMS, JOHN Hreporter.nih.gov
Unravelling disease tolerance and host resistance in afebrile P. falciparum infections: a prospective study in Mozambican adultsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$540,228June 1, 2020May 31, 2026AIDE, PEDROreporter.nih.gov
Exocytosis of Plasmodium egress and invasion organellesNIHNational Institute of Allergy and Infectious Diseases2023$540,193August 22, 2023July 31, 2025MURALIDHARAN, VASANTreporter.nih.gov
Antigen discovery for transmission-blocking vaccines in Plasmodium vivaxNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$540,000April 6, 2020February 28, 2025CAO, YAMINGreporter.nih.gov
Monitoring the development of resistance to the novel insecticide clothianidin in Anopheles gambiaeNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$540,000May 1, 2020April 30, 2025KAMGANG, BASILEreporter.nih.gov
The Skin Phase of Malaria InfectionNIHNational Institute of Allergy and Infectious Diseases2021$536,335July 6, 2017June 30, 2024SINNIS, PHOTINIreporter.nih.gov
Impact of malaria vector diversity on intervention strategiesNIHFogarty International Center2021 to 2024$534,732September 18, 2020August 31, 2025MCCANN, ROBERT SEANreporter.nih.gov
"Investigating the rebound effects of seasonal malaria chemoprevention (SMC) in Mali"NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$525,914September 5, 2022August 31, 2027TOURE, MAHAMOUDOUreporter.nih.gov
Preparing for a world with artemisinin resistance: using individual-based epidemiological modeling to minimize the long-term detrimental effects of antimalarial drug resistanceNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$523,000August 10, 2020July 31, 2025BONI, MACIEJ Freporter.nih.gov
Evaluating the impact of pre-existing humoral immunity on hepatocyte deathNIHNational Institute of Allergy and Infectious Diseases2025$516,175June 23, 2025May 31, 2027KAUSHANSKY, ALEXISreporter.nih.gov
Risk stratification of malaria among school-age children with mHealth spectroscopy of blood analysisNIHFogarty International Center2024 to 2025$513,058September 1, 2022May 31, 2027KIM, YOUNG Lreporter.nih.gov
Novel artemisinin derivatives for chemogenomic profiling of Plasmodium falciparumNIHNational Institute of General Medical Sciences2021 to 2023$512,118June 1, 2020May 31, 2024CARVALHO, PAULO BATISTA DEreporter.nih.gov
Role of the gut microbiota in shaping severity of malariaNIHNational Institute of Allergy and Infectious Diseases2021$511,182January 11, 2017December 31, 2022SCHMIDT, NATHANreporter.nih.gov
Epidemiology of Malaria Invasion in Mutare City and Targets for Elimination, ZimbabweNIHFogarty International Center2021 to 2025$506,128September 17, 2021May 31, 2026MHARAKURWA, SUNGANOreporter.nih.gov
Development of phenolic small molecule inhibitors of PfATP6, a Plasmodium calcium ATPaseNIHNational Institute of General Medical Sciences2023 to 2025$502,201May 1, 2023April 30, 2027PAULA, STEFAN FRANZreporter.nih.gov
Cryo-ET structure of the Plasmodium basal complexNIHNational Institute of Allergy and Infectious Diseases2025$501,800August 4, 2025July 31, 2027DVORIN, JEFFREY Dreporter.nih.gov
Identifying the targets of protective immunity to severe falciparum malariaNIHNational Institute of Allergy and Infectious Diseases2023$500,144September 4, 2023August 31, 2024KURTIS, JONATHAN D.reporter.nih.gov
Human-informed data-driven development of next-generation T cell vaccine against malariaNIHNational Institute of Allergy and Infectious Diseases2022$495,904September 2, 2022January 1, 2023DOOLAN, DENISE L.reporter.nih.gov
Determining Mechanisms of Cerebral Blood Flow and Metabolism Derangements in Pediatric Cerebral Malaria (FLOW)NIHNational Institute of Neurological Disorders and Stroke2024$490,977May 15, 2024April 30, 2026OBRIEN, NICOLEreporter.nih.gov
Empowering functional genomics of An. gambiae through inversion genotypingNIHNational Institute of Allergy and Infectious Diseases2021$490,582February 14, 2017January 31, 2024BESANSKY, NORA JESSIEreporter.nih.gov
Functional characterization of striated fiber assemblins in malaria parasitesNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$486,750August 21, 2023July 31, 2025DVORIN, JEFFREY Dreporter.nih.gov
Generating a novel dual stage malaria vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$485,375September 24, 2021August 31, 2023PEPPER, MARIONreporter.nih.gov
Multiplex analysis of IgA and IgG antibody responses to early childhood malaria infections to inform vaccine developmentNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$482,617May 2, 2023April 30, 2026BERRY, ANDREAreporter.nih.gov
Collaborative Research: Impacts of the African Origin of Plasmodium vivax on Contemporary Parasite PopulationsNIHFogarty International Center2021$479,595July 20, 2017March 31, 2023JULIANO, JONATHAN Jreporter.nih.gov
Mechanisms Governing Translational Regulation During Plasmodium TransmissionNIHNational Institute of Allergy and Infectious Diseases2022$477,453November 1, 2016August 31, 2024LINDNER, SCOTT Ereporter.nih.gov
Mechanisms of acute kidney injury in malaria - Resubmission - 1NIHNational Institute of Allergy and Infectious Diseases2021 to 2022$476,248December 15, 2020November 30, 2023RODRIGUEZ, ANAreporter.nih.gov
A Chemical Vaccine for MalariaNIHNational Institute of Allergy and Infectious Diseases2021$473,670September 19, 2019August 31, 2023SHAPIRO, THERESA Areporter.nih.gov
Investigating the Mechanisms Underlying Mosquito Infectiousness in MalariaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$472,836June 6, 2024April 30, 2027SINNIS, PHOTINIreporter.nih.gov
Molecular Determinants of Sporozoite / Host Cell InteractionsNIHNational Institute of Allergy and Infectious Diseases2021$470,750July 9, 2018June 30, 2022KAPPE, STEFAN HIreporter.nih.gov
Novel nanoparticles function as chemo- and adjunctive-therapy against experimental cerebral malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$468,500December 1, 2020November 30, 2023VAN DER HEYDE, HENRI Creporter.nih.gov
New strategies to study malaria-induced acute kidney injuryNIHNational Institute of General Medical Sciences2021 to 2023$467,755September 15, 2021August 31, 2024GALLEGO-DELGADO, JULIOreporter.nih.gov
Mechanisms of anemia in malariaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$466,125June 13, 2024April 30, 2026RODRIGUEZ, ANAreporter.nih.gov
Measuring the transmissibility of recurrent parasitemias that arise following artemisinin-based combination therapyNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$465,093January 17, 2024November 30, 2026LIN, JESSICAreporter.nih.gov
Molecular Genetics of Avian Malaria VirusesNIHNational Institute of General Medical Sciences2022 to 2025$465,000May 1, 2022March 31, 2027SEHGAL, RAVINDER NATH MARIUSreporter.nih.gov
Development and Composition of the Basal Complex During Plasmodium SporogonyNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$463,973May 23, 2024September 30, 2026LINDNER, SCOTT Ereporter.nih.gov
Identifying adjunctive therapy in the experimental model of malaria to improve cerebral malaria outcomesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$462,000June 11, 2021May 31, 2024DAILY, JOHANNA PATRICIAreporter.nih.gov
Malaria and allergic inflammatory changes to the gut barrierNIHNational Institute of Allergy and Infectious Diseases2021$460,341June 1, 2018May 31, 2024LUCKHART, SHIRLEYreporter.nih.gov
Designing a diversity-covering multiantigen multi-strain malaria vaccineNIHNational Heart, Lung, and Blood Institute2021 to 2023$457,659August 2, 2019July 31, 2025OUATTARA, AMEDreporter.nih.gov
Parasite-specific proteasome inhibitors to combat multi-drug resistant malariaNIHNational Institute of Allergy and Infectious Diseases2021$454,467December 9, 2016February 28, 2023BOGYO, MATTHEWreporter.nih.gov
Mitigation of erythrocyte adhesion in human malariaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$453,750July 9, 2024November 30, 2026CHISHTI, ATHAR H.reporter.nih.gov
Precise field-friendly methods for quantification of antimalarial drugs in dried blood spotsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$451,000July 17, 2024May 31, 2027HUANG, LIUSHENGreporter.nih.gov
Comprehensive, high-resolution arrays to trace the development of antibody responses to variant Plasmodium falciparum antigens in naturally exposed cohortsNIHNational Institute of Allergy and Infectious Diseases2025$451,000August 15, 2025July 31, 2027GREENHOUSE, BRYAN Rreporter.nih.gov
Complete Plasmodium falciparum infection cycle modelNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$450,313November 7, 2022October 31, 2025DIMOPOULOS, GEORGEreporter.nih.gov
Effect of gut microbiota composition on malaria vaccine-induced immune responsesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$449,728June 24, 2024April 30, 2026SCHMIDT, NATHANreporter.nih.gov
Parasite variant surface antigen expression and immune gaps in severe malariaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$448,550July 9, 2024May 31, 2027TRAVASSOS, MARK Areporter.nih.gov
Deciphering the role of Plasmodium falciparum plasmepsin 2/3 amplifications in mutant pfcrt-driven piperaquine resistanceNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$445,500March 18, 2021February 29, 2024FIDOCK, DAVID Areporter.nih.gov
Characterization of Plasmodium falciparum long non-coding RNAs and their roles in gene regulationNIHNational Institute of Allergy and Infectious Diseases2025$445,488July 1, 2025June 30, 2027SERRE, DAVIDreporter.nih.gov
Longitudinal cohort study of SARS-CoV2 sero-conversion in a malaria-endemic community in Western KenyaNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$445,240December 10, 2021November 30, 2024TAYLOR, STEVE MYERreporter.nih.gov
Assessing the role of liver stage antigens-specific antibodies against Plasmodium falciparum liver stage infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$445,142April 15, 2021October 31, 2024KRZYCH, URSZULAreporter.nih.gov
Unbound piperaquine pharmacokinetic exposure in Ugandan pregnant women and children receiving malaria chemopreventionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$444,125June 28, 2021May 31, 2024HUANG, LIUSHENGreporter.nih.gov
Delineating host, parasite and pharmacologic factors impacting the treatment of malaria in children with and without HIVNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2023$441,844September 7, 2022August 31, 2025PARIKH, SUNILreporter.nih.gov
Novel Dual-Stage Antimalarials: Machine learning prediction, validation and evolutionNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$441,319July 3, 2023December 31, 2025FREUNDLICH, JOEL STEPHENreporter.nih.gov
Discovering resistance-resistant antimalarial drug targetNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$441,100June 23, 2023May 31, 2026LLINAS, MANUELreporter.nih.gov
Non-invasive detection of malaria parasites in vitro and in Cameroonian adultsNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$439,420April 25, 2022March 31, 2025PARIKH, SUNILreporter.nih.gov
Developing a barcoded malaria parasite panel to assess broadly neutralizing antibodiesNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$438,625June 29, 2022November 30, 2024DURAISINGH, MANOJ Treporter.nih.gov
Evaluating host-directed therapeutics against blood-stage malaria parasitesNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$438,625July 14, 2022June 30, 2024DURAISINGH, MANOJ Treporter.nih.gov
Linking metabolite sensing and gene expression in malaria parasitesNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$438,625November 9, 2022October 31, 2025DURAISINGH, MANOJ Treporter.nih.gov
Understanding Plasmodium vivax transmission networks through a novel microhaplotype and kinship analysis approachNIHNational Institute of Allergy and Infectious Diseases2025$437,625August 1, 2025July 31, 2027HEMMING-SCHROEDER, ELIZABETH ANNEreporter.nih.gov
A chromosome-level genome assembly for the major African malaria vector Anopheles gambiaeNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$435,912February 5, 2021January 31, 2025SHARAKHOV, IGOR Vreporter.nih.gov
Fungal metabolites block malaria transmissionNIHNational Institute of Allergy and Infectious Diseases2021$435,341July 15, 2017June 30, 2024LI, JUNreporter.nih.gov
Structure of Malaria Parasite RNA polymeraseNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$435,023January 21, 2022December 31, 2024MURAKAMI, KATSUHIKOreporter.nih.gov
Understanding immune regulation in blood-stage malariaNIHNational Institute of Allergy and Infectious Diseases2021$433,809May 1, 2012June 30, 2022HARTY, JOHN Treporter.nih.gov
Buy the world a coke and keep it mosquito freeNIHNational Institute of Allergy and Infectious Diseases2025$433,303June 18, 2025May 31, 2027SCHEEL, MOLLY DUMANreporter.nih.gov
Investigating gene regulatory networks in immune cells of children who differ in susceptibility to malaria infection using single-cell approachesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$432,218January 1, 2021June 30, 2024TRAN, TUAN MANHreporter.nih.gov
Development of Novel Natural Product Inspired Antileishmanial DrugsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$431,186April 2, 2021March 31, 2024LANDFEAR, SCOTT Mreporter.nih.gov
Specificity of Plasmodium falciparum protein exportNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$430,834June 1, 2022May 31, 2024GOLDBERG, DANIEL E.reporter.nih.gov
The Impact of Novel Vector Control Tools on Asymptomatic Plasmodium falciparum Infection Prevalence and Transmission PotentialNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$430,375June 10, 2024April 30, 2027KOEPFLI, CRISTIANreporter.nih.gov
Deciphering P. falciparum artemisinin resistance in Bangladesh: a genotypic-phenotypic evaluation of Kelch13 dependent and independent determinantsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$430,375May 31, 2024March 31, 2027MUKHERJEE, ANGANAreporter.nih.gov
Silencing Anopheles stephensiNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$429,931November 16, 2023October 31, 2025SCHEEL, MOLLY DUMANreporter.nih.gov
High throughput chemoenzymatic synthesis of antimalarial compoundsNIHNational Center for Complementary & Integrative Health2022 to 2023$429,000September 1, 2022August 31, 2025NARAYAN, ALISONreporter.nih.gov
A chromatin structure informed exploration of gene regulation in Anopheles coluzziiNIHNational Institute of Allergy and Infectious Diseases2025$429,000June 25, 2025May 31, 2027RIEHLE, MICHELLE Mreporter.nih.gov
Computer Vision for Malaria Microscopy: Automated Detection and Classification of Plasmodium for Basic Science and Pre-Clinical ApplicationsNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$428,284September 1, 2023August 31, 2025IPPOLITO, MATTHEW MICHAELreporter.nih.gov
Defining the effect of Plasmodium infection on Ebola virus vaccine efficacyNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$427,625August 11, 2023July 31, 2025MAURY, WENDY JEANreporter.nih.gov
Mechanism of neutrophil dysfunction by Plasmodium falciparum secreted histidine-rich protein IINIHNational Institute of Allergy and Infectious Diseases2024 to 2025$427,625July 22, 2024May 31, 2027GOLDBERG, DANIEL E.reporter.nih.gov
Paired inhibition of falciparum merozoite invasionNIHNational Institute of Allergy and Infectious Diseases2025$426,938August 1, 2025July 31, 2027SHAPIRO, THERESA Areporter.nih.gov
Serological Biomarkers for Monitoring Human-Vector Contact by Invasive Anopheles stephensi in AfricaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$425,863February 2, 2024December 31, 2026YAN, GUIYUNreporter.nih.gov
Developing resistance-breaking insecticides at mosquito muscarinic acetylcholine receptors to reduce malaria transmissionNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$424,925August 20, 2021July 31, 2025GROSS, AARON DONALDreporter.nih.gov
Design and Evaluation of a Plasmodium vivax ultra-dense peptide arrayNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$424,875March 15, 2021February 28, 2023SERRE, DAVIDreporter.nih.gov
Impact of infection complexity on P. falciparum sexual commitment and gametocytemiaNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$424,875April 1, 2023March 31, 2026HARRISON, SHANNON TAKALAreporter.nih.gov
Intracellular-acting antibodies for the prevention of malaria liver stage infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$423,500November 4, 2022October 31, 2024WILDER, BRANDON KEITHreporter.nih.gov
Function of a putative iron transporter in the Plasmodium apicoplastNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$423,500May 16, 2024March 31, 2026SIGALA, PAUL Areporter.nih.gov
Innate iNKT Cells Shape Organ-Specific Pathogenesis in Plasmodium InfectionNIHNational Institute of Allergy and Infectious Diseases2025$423,500July 17, 2025June 30, 2027LAMB, TRACEY JANEreporter.nih.gov
New tools for antimalarial target identificationNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$422,977March 22, 2019February 28, 2025WICHT, KATHRYN JEANreporter.nih.gov
Development of genetic tools for the study of mosquito hemocytesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$420,750September 24, 2021August 31, 2024SMITH, RYAN C.reporter.nih.gov
Molecular mechanism of gamete fusion in malaria parasiteNIHNational Institute of Allergy and Infectious Diseases2025$420,750August 6, 2025July 31, 2027KUMAR, SUDHIRreporter.nih.gov
Quantifying Redox Potentials for Artemisinin Resistant (ARTR) MalariaNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$419,760April 8, 2022March 31, 2025ROEPE, PAUL D.reporter.nih.gov
Genetic and Immunological Control for Development of Asymptomatic MalariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$419,375June 1, 2021May 31, 2024LAMB, TRACEY JANEreporter.nih.gov
Plasmodium ovale hypnozoite development and relapse: a coordinated in vivo in vitro studyNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$417,602November 17, 2020October 31, 2024LIN, JESSICAreporter.nih.gov
A Novel Hydrology-based Malaria Transmission Model and Field ApplicationsNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$417,500November 7, 2022October 31, 2025YAN, GUIYUNreporter.nih.gov
Training of machine learning algorithms for the classification of accelerometer-measured bednet use and related behaviors associated with malaria riskNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$416,901August 4, 2023July 31, 2025KREZANOSKI, PAUL JOSEPHreporter.nih.gov
Integrating a pre-erythrocytic component into a multistage malaria vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$416,125November 12, 2020October 31, 2023BURNS, JAMES MATTHEWreporter.nih.gov
Longitudinal Antibody Profiles Correlated with Protection from Malaria in MalawiNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$415,919January 8, 2021December 31, 2023VALIM, CLARISSAreporter.nih.gov
Essential function of a putative glycosyltransferase in P. falciparumNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$415,250April 5, 2021March 31, 2024MURALIDHARAN, VASANTreporter.nih.gov
Elucidating mechanisms for artemisinin-induced dormancy in Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$415,250August 16, 2023July 31, 2025KYLE, DENNIS Ereporter.nih.gov
Comparative transcriptomics of Plasmodium vivax strains to understand hypnozoite formationNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$415,250June 7, 2024April 30, 2027JOYNER, CHESTER J.reporter.nih.gov
Sensitive and quantitative malaria diagnostic using nanoscale porous silicon.NIHNational Institute of Allergy and Infectious Diseases2021 to 2022$414,988November 24, 2020October 31, 2023WEISS, SHARON Mreporter.nih.gov
Investigating the role of oxygen on Plasmodium multiplication rateNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$414,537November 10, 2022October 31, 2025CORDY, REGINA Jreporter.nih.gov
PfVP1, a battery of the malaria parasite, is critical for ring stage developmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$413,790November 10, 2020October 31, 2023KE, HANGJUNreporter.nih.gov
Larval Ecology of Invasive Anopheles stephensi in EthiopiaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$413,617February 7, 2024December 31, 2026ZHOU, GUOFAreporter.nih.gov
Acute brain injury and blood-brain barrier dysfunction in cerebral malaria (ABC)NIHNational Institute of Neurological Disorders and Stroke2022 to 2023$413,606February 15, 2022January 31, 2024DATTA, DIBYADYUTIreporter.nih.gov
High Throughput Screening of Medicines for Malaria Ventures Chemical Libraries to Identify Novel Inhibitors of Candida aurisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$412,500April 6, 2021March 31, 2025LOPEZ-RIBOT, JOSE L.reporter.nih.gov
Evaluation of Immunodominant fragments of PfGARP for malaria vaccine developmentNIHNational Institute of Allergy and Infectious Diseases2025$412,500July 3, 2025June 30, 2027RAJ, DIPAK KUMARreporter.nih.gov
Malaria parasite harbors a unique protein lysine methyltransferase targeting both chromatin and motility machineryNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$412,375May 24, 2023April 30, 2026MIAO, JUNreporter.nih.gov
UIS2 function in establishing transport mechanisms at the malaria parasite-host cell interfaceNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$411,719November 10, 2022October 31, 2025BECK, JOSH RYANreporter.nih.gov
Perturbations of host cell signaling by a complex hepatotropic pathogenNIHNational Institute of General Medical Sciences2021$411,599April 1, 2013February 19, 2023KAUSHANSKY, ALEXISreporter.nih.gov
Assessing the Impact of Treatment of Asymptomatic Malaria Infections on Inflammation and Cognition in SchoolchildrenNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$410,699January 25, 2024November 30, 2025TRAN, TUAN MANHreporter.nih.gov
Evolutionary Dynamics of Zoonotic MalariaNIHNational Institute of Allergy and Infectious Diseases2025$409,943January 25, 2023December 31, 2027GOLDBERG, AMYreporter.nih.gov
Molecular mechanisms of Plasmodium fertilizationNIHNational Institute of Allergy and Infectious Diseases2021$409,375December 7, 2016November 30, 2022JACOBS-LORENA, MARCELOreporter.nih.gov
Regulation of macrophage function during acute infection with PlasmodiumNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$409,172June 1, 2024April 30, 2026STUMHOFER, JASON Sreporter.nih.gov
Ecology and genetics of insecticide resistance in African malaria vectorsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$407,000March 1, 2016February 29, 2028AFRANE, YAW ASAREreporter.nih.gov
Continuous in vitro culture and genetics of Plasmodium vivax in a bespoke blood cell bioreactorNIHNational Institute of Allergy and Infectious Diseases2025$406,450April 7, 2025March 31, 2028DURAISINGH, MANOJ Treporter.nih.gov
Multi-target blood stage vaccine against Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2021$406,250December 13, 2019November 30, 2021RAJ, DIPAK KUMARreporter.nih.gov
Quantifying the dual threat of Plasmodium vivax and Anopheles stephensi in a P. falciparum endemic pre-elimination setting in sub-Saharan AfricaNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$406,015August 1, 2023July 31, 2025PRUDHOMMEOMEARA, WENDYreporter.nih.gov
Genomics and sero-epidemiology of Plasmodium falciparum malaria in a pre-elimination settingNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$401,331April 1, 2023March 31, 2028SAENZ, FABIAN ERNESTOreporter.nih.gov
Profiling malarial lipid biosynthesis and key acyl-coenzyme A synthetase activities with fatty acid alkynesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$400,625July 2, 2024May 31, 2027KLEMBA, MICHAELreporter.nih.gov
Anti-Malarial Drug Leads from FungiNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$398,769May 21, 2021April 30, 2024OBERLIES, NICHOLAS H.reporter.nih.gov
New approaches to measuring and containing the spatial spread of human pathogensNIHNational Institute of General Medical Sciences2021$398,323August 15, 2017July 31, 2022BUCKEE, CAROLINE O'FLAHERTYreporter.nih.gov
Transcranial Doppler Ultrasonography Clinical and Research Centers of Excellence in Sub-Saharan AfricaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$393,121August 1, 2021July 31, 2024OBRIEN, NICOLEreporter.nih.gov
Characterizing malaria vector competence among natural populations of AnophelesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$392,833December 15, 2020November 30, 2023LAUFER, MIRIAM K.reporter.nih.gov
Establishing strains and conditions for long-term P. vivax culturesNIHNational Institute of Allergy and Infectious Diseases2025$392,710December 6, 2024November 30, 2027JOYNER, CHESTER J.reporter.nih.gov
Disrupting Apicoplast DNA Replication in Plasmodium: Identifying Key Proteases for Antimalarial TherapyNIHNational Institute of Allergy and Infectious Diseases2025$385,816July 24, 2025June 30, 2027NELSON, SCOTT W.reporter.nih.gov
Mechanisms Governing Translational Regulation During Plasmodium TransmissionNIHNational Institute of Allergy and Infectious Diseases2021$385,703November 1, 2016October 31, 2021LINDNER, SCOTT Ereporter.nih.gov
Anopheles FBG: a novel malaria transmission-blocking vaccine targetNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$384,730November 8, 2022October 31, 2025LI, JUNreporter.nih.gov
Suppression of anti-malarial humoral immune responses by gamaherpesvirusesNIHNational Institute of Allergy and Infectious Diseases2021$383,290March 1, 2017November 30, 2021LAMB, TRACEY JANEreporter.nih.gov
Impact of P. falciparum diversity on transmission reducing immunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$382,428July 1, 2018June 30, 2024COHEE, LAUREN Mreporter.nih.gov
Gene delivery for Anopheles mosquitoesNIHNational Institute of Allergy and Infectious Diseases2022$380,762May 10, 2017April 30, 2024RASGON, JASON Lreporter.nih.gov
Epigenetic Reprogramming of Monocyte Functions during Acute Uncomplicated Malaria in Kenyan ChildrenNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$379,150January 24, 2018December 31, 2023DOBBS, KATHERINE ROSEreporter.nih.gov
Analysis of active genetic elements in germline and somatic cell lineagesNIHNational Institute of General Medical Sciences2025$376,498August 1, 2025July 31, 2030BIER, ETHANreporter.nih.gov
Functions of mRNPs in RNA metabolism in Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2025$375,000June 10, 2025May 31, 2030CUI, LIWANGreporter.nih.gov
Mechanisms of Neuroinflammation in Experimental Cerebal MalariaNIHNational Institute of Neurological Disorders and Stroke2021$373,913September 1, 2018August 31, 2022STEPHENS, ROBINreporter.nih.gov
Characterizing the spatial epidemiology of urban malaria infection in Accra, Ghana (MUSE)NIHNational Institute of Allergy and Infectious Diseases2023 to 2024$371,618February 28, 2023January 31, 2026STRESMAN, GILLIANreporter.nih.gov
Modulation of the B cell response to dengue virus infection by Plasmodium falciparum co-infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$370,546July 1, 2018June 30, 2024VU, DAVID MANH-TUNGreporter.nih.gov
Synthesizing immunoinformatics and genetic epidemiology to identify signatures of natural functional immunity to malaria parasitesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$369,354March 1, 2023February 29, 2028MARKWALTER, CHRISTINEreporter.nih.gov
Development of novel malaria pre-erythrocytic vaccine antigens targeting Plasmodium sporozoite liver infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$368,224January 4, 2023December 31, 2025CHA, SUNG-JAEreporter.nih.gov
The development and evaluation of portable experimental huts for global malaria vector control decision-makingNIHNational Institute of Allergy and Infectious Diseases2025$366,845August 18, 2025July 31, 2027MESSENGER, LOUISA ALEXANDRAreporter.nih.gov
High-throughput mapping of human antibody sequences to PfEMP1 malaria antigen specificityNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$360,399July 7, 2021June 30, 2024HVIID, LARSreporter.nih.gov
EphA2 mediates opening of the blood brain barrier in cerebral malariaNIHNational Institute of Neurological Disorders and Stroke2021$356,155March 1, 2017February 28, 2023LAMB, TRACEY JANEreporter.nih.gov
Blood-Biomarkers and Risk Factors of Acute Brain Injury associated with Neurodisability in Ugandan Children [BRAIN-Child]NIHNational Institute of Neurological Disorders and Stroke2022 to 2023$351,649August 15, 2022July 31, 2025DATTA, DIBYADYUTIreporter.nih.gov
The Effect of Maternal Cells on Infant ImmunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$341,450December 12, 2017July 31, 2023HARRINGTON, WHITNEY ELIZABETHreporter.nih.gov
Reducing malaria in pregnancy through focal drug administration in household members: A pilot feasibility trialNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$341,293June 1, 2025May 31, 2027BOYCE, ROSS MATHEWreporter.nih.gov
Noguchi Institute Initiative for NTDs Elimination (NIINE)NIHNational Institute of Allergy and Infectious Diseases2021$339,541April 14, 2017March 31, 2023WILSON, MICHAEL Dreporter.nih.gov
Risk stratification of malaria among school-age children with mHealth spectroscopy of blood analysisNIHFogarty International Center2022 to 2023$339,338September 1, 2022July 31, 2024KIM, YOUNG Lreporter.nih.gov
Large Scale systematic priorization of Plasmodium vivax blood stage vaccine antigensNIHNational Institute of Allergy and Infectious Diseases2021$318,040February 14, 2018January 31, 2023RAYNER, JULIAN CHARLESreporter.nih.gov
Mechanisms of Neuroinflammation in Experimental Cerebal MalariaNIHNational Institute of Neurological Disorders and Stroke2023$308,938September 1, 2022August 31, 2024STEPHENS, ROBINreporter.nih.gov
A systems biology investigation of the interplay between gut microbes and blood metabolites in the development of malarial anemiaNIHNational Heart, Lung, and Blood Institute2021 to 2022$305,027August 20, 2018July 31, 2024CORDY, REGINA Jreporter.nih.gov
Mathematical modeling of immune response to malariaNIHNational Institute of General Medical Sciences2021$303,690March 1, 2017February 28, 2023GANUSOV, VITALY V.reporter.nih.gov
A genetically modified Plasmodium falciparum sporozoite vaccine attenuated at the late-liver stage.NIHNational Institute of Allergy and Infectious Diseases2021$300,000April 21, 2020March 31, 2023HOFFMAN, STEPHEN LEVreporter.nih.gov
Development of Monoclonal Antibody-mediated Interventions to Combat MalariaNIHNational Institute of Allergy and Infectious Diseases2022$300,000July 5, 2022GAO, WENDAreporter.nih.gov
NOVEL DIAGNOSTIC BIOMARKERS DISCOVERY AND VALIDATION FOR MALARIANIHNational Institute of Allergy and Infectious Diseases2025$300,000December 1, 2024November 30, 2025LEDIZET, MICHELreporter.nih.gov
Enhancement of gametocytogenesis in Plasmodium falciparum by genetic engineering for improved PfSPZ Vaccine ManufactureNIHNational Institute of Allergy and Infectious Diseases2021$299,994August 17, 2020July 31, 2023HOFFMAN, STEPHEN LEVreporter.nih.gov
PfAg, a multivalent peptide vaccine against malariaNIHNational Institute of Allergy and Infectious Diseases2025$299,954September 15, 2025August 31, 2027CHUANG, YU-MINreporter.nih.gov
CRISPR-based Tropical Infection DiagnosticsNIHNational Institute of Allergy and Infectious Diseases2023$299,937September 15, 2023September 14, 2024ZHUKOV, DMITRYreporter.nih.gov
Development of monoclonal antibody-mediated interventions to combat malariaNIHNational Institute of Allergy and Infectious Diseases2022$299,777August 26, 2022MILLER, JACQUELINEreporter.nih.gov
A vaccine targeting mosquito metabolic pathways to eradicate malariaNIHNational Institute of Allergy and Infectious Diseases2025$299,644September 23, 2025August 31, 2027CHUANG, YU-MINreporter.nih.gov
Benzoxaborole-based antimalarial drug discoveryNIHNational Institute of Allergy and Infectious Diseases2021$299,639July 8, 2020June 30, 2023AUBREY, MARISSAreporter.nih.gov
CRISPR-Based in Vitro Diagnostic Device for Rapid Detection of Eukaryotic PathogensNIHNational Institute of Allergy and Infectious Diseases2023$299,610September 15, 2023September 14, 2024SILVERMAN, ANDREWreporter.nih.gov
Development of monoclonal antibody-mediated interventions to combat malariaNIHNational Institute of Allergy and Infectious Diseases2022$298,596August 30, 2022August 31, 2023RUPPRECHT, SUSANreporter.nih.gov
E. coli platform for expression of low-cost malaria fusion proteinsNIHNational Institute of Allergy and Infectious Diseases2024$297,809January 1, 2024June 30, 2025LEES, ANDREWreporter.nih.gov
Identification and validation of molecular markers of piperaquine resistanceNIHNational Institute of Allergy and Infectious Diseases2021$289,910February 3, 2017January 31, 2024HARRISON, SHANNON TAKALAreporter.nih.gov
Delineating the kidney brain axis in children with severe malaria (KID-BRAIN)NIHFogarty International Center2023 to 2025$289,502August 20, 2023April 30, 2028BATTE, ANTHONYreporter.nih.gov
Role of primaquine pharmacokinetics in treatment efficacy for vivax malariaNIHNational Institute of Allergy and Infectious Diseases2022$284,968June 10, 2022May 31, 2023SPRING, MICHELEreporter.nih.gov
The impact of antimalarials and insecticide resistance on malaria transmission in UgandaNIHFogarty International Center2021 to 2022$282,448September 21, 2018January 31, 2023CONRAD, MELISSA Dreporter.nih.gov
Real-World Impact of Next Generation Insecticidal Nets for Malaria Control in Rural Western KenyaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$280,939April 1, 2024March 31, 2029MANGENI, JUDITHreporter.nih.gov
Functional characterization of the Plasmodium falciparum invasion ligand bindomeNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$277,318May 16, 2024May 14, 2025KANJEE, USHEERreporter.nih.gov
Leveraging access to parasite natural diversity to identify Plasmodium vivax culture-adaptable strain.NIHNational Institute of Allergy and Infectious Diseases2025$267,168December 27, 2024November 30, 2027POPOVICI, JEANreporter.nih.gov
Measuring spillover effects of reactive, focal malaria elimination interventionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$258,515June 10, 2019May 31, 2024BENJAMIN-CHUNG, JADEreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
University of California, San FranciscoSan Francisco, CA32$52.4 million0$0
Sanaria, Inc.Rockville, MD20$39.5 million0$0
Seattle Children's HospitalSeattle, WA18$36.4 million0$0
University of WashingtonSeattle, WA12$27.3 million0$0
Duke UniversityDurham, NC19$24 million0$0
Harvard University D/b/a Harvard School of Public HealthBoston, MA21$22.2 million0$0
University of Maryland BaltimoreBaltimore, MD26$22 million0$0
Johns Hopkins UniversityBaltimore, MD23$20 million0$0
Columbia University Health SciencesNew York, NY13$18.9 million0$0
Indiana University IndianapolisIndianapolis, IN16$18.5 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC19$18 million0$0
Weill Medical Coll of Cornell UnivNew York, NY10$18 million0$0
Stanford UniversityStanford, CA11$16.6 million0$0
University of South FloridaTampa, FL16$16.2 million0$0
Kaiser Foundation Research InstituteOakland, CA2$14.8 million0$0
Oregon Health & Science UniversityPortland, OR10$14.7 million0$0
Drexel UniversityPhiladelphia, PA9$12.4 million0$0
Yale UniversityNew Haven, CT12$11.5 million0$0
University of IowaIowa City, IA12$11.3 million0$0
University of California, San DiegoLa Jolla, CA7$10.4 million0$0
University of Georgia Research Foundation IncAthens, GA13$10.1 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA4$9.8 million0$0
Brown UniversityProvidence, RI8$9.6 million0$0
Ut Southwestern Medical CenterDallas, TX5$9.5 million0$0
Boston Children's HospitalBoston, MA8$9 million0$0
Case Western Reserve UniversityCleveland, OH6$8.8 million0$0
Portland State UniversityPortland, OR3$7.7 million0$0
Massachusetts General HospitalBoston, MA3$7.6 million0$0
University of California-IrvineIrvine, CA8$7.5 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH2$7.2 million0$0
The University of Central Florida Board of TrusteesOrlando, FL3$6.9 million0$0
Michigan State UniversityEast Lansing, MI4$6.9 million0$0
University of New Mexico Health Scis CTRAlbuquerque, NM3$6 million0$0
Children's Research InstituteWashington, DC2$5.7 million0$0
University of UtahSalt Lake City, UT8$5.6 million0$0
Washington UniversitySaint Louis, MO9$5.4 million0$0
Tulane University of LouisianaNew Orleans, LA2$5.4 million0$0
Institute for Systems BiologySeattle, WA2$5.3 million0$0
Henry M. Jackson FDN for the Adv Mil/medBethesda, MD4$5.2 million0$0
University of MinnesotaMinneapolis, MN4$4.8 million0$0
New York University School of MedicineNew York, NY5$4.5 million0$0
University of Colorado DenverAurora, CO2$4.4 million0$0
University of RochesterRochester, NY4$4.2 million0$0
Boston University Medical CampusBoston, MA4$3.9 million0$0
Institut Pasteur du CambodgePhnom Penh3$3.8 million0$0
Texas Biomedical Research InstituteSan Antonio, TX2$3.7 million0$0
University of Texas HLTH Science CenterSan Antonio, TX4$3.7 million0$0
University of OxfordOxford1$3.6 million0$0
Pennsylvania State Univ University ParkUniversity Park, PA7$3.6 million0$0
University of California-RiversideRiverside, CA4$3.5 million0$0
University of VirginiaCharlottesville, VA2$3.5 million0$0
Iowa State UniversityAmes, IA6$3.4 million0$0
University of Vermont & ST Agric CollegeBurlington, VT1$3.4 million0$0
Chromologic, LLCMonrovia, CA3$3.3 million0$0
Cornell UniversityIthaca, NY1$3.1 million0$0
Isca Technologies, Inc.Riverside, CA1$3 million0$0
Visionquest Biomedical INCAlbuquerque, NM2$3 million0$0
University of Illinois at ChicagoChicago, IL1$3 million0$0
Lumen Bioscience, Inc.Seattle, WA1$2.9 million0$0
Analytical Diagnostic Solutions, Inc.Mount Laurel, NJ1$2.9 million0$0
Albert Einstein College of MedicineBronx, NY3$2.8 million0$0
Regents of the University of IdahoMoscow, ID2$2.6 million0$0
Georgetown UniversityWashington, DC3$2.6 million0$0
Leiden University Medical CenterLeiden1$2.6 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ3$2.4 million0$0
Caucaseco Scientific Research CenterCali2$2.4 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA2$2.4 million0$0
Virginia Polytechnic Institute and State UniversityBlacksburg, VA6$2.4 million0$0
University of California-BerkeleyBerkeley, CA2$2.3 million0$0
Redbud Labs, Inc.Durham, NC1$2.3 million0$0
Mayo Clinic RochesterRochester, MN2$2.3 million0$0
Univ of Sciences, Tech & Tech of BamakoBamako3$2.3 million0$0
University of Notre DameNotre Dame, IN5$2.2 million0$0
Makerere University College of Health SciencesKampala3$2.2 million0$0
Northeastern UniversityBoston, MA1$2.1 million0$0
Fred Hutchinson Cancer CenterSeattle, WA1$2.1 million0$0
Vaccine Research Institute of San DiegoSan Diego, CA1$2.1 million0$0
Vanderbilt UniversityNashville, TN3$2.1 million0$0
Tufts University BostonBoston, MA2$2 million0$0
Versatope Therapeutics, Inc.Lowell, MA1$2 million0$0
Medical College of WisconsinMilwaukee, WI3$1.9 million0$0
Morehouse School of MedicineAtlanta, GA2$1.9 million0$0
University of ArizonaTucson, AZ1$1.9 million0$0
Tmliverpool School of Tropical MedicineLiverpool1$1.8 million0$0
Cure Systems LLCNewton Center, MA2$1.8 million0$0
Colorado State UniversityFort Collins, CO2$1.8 million0$0
SUNY at BuffaloAmherst, NY2$1.7 million0$0
Mcgill UniversityMontreal1$1.7 million0$0
Ohio State UniversityColumbus, OH2$1.7 million0$0
University of FloridaGainesville, FL2$1.7 million0$0
University of GhanaLegon2$1.6 million0$0
University of Cape TownRondebosch2$1.6 million0$0
Wadsworth CenterMenands, NY1$1.6 million0$0
Hennepin Healthcare Research InstituteMinneapolis, MN4$1.6 million0$0
Idaho State UniversityPocatello, ID1$1.6 million0$0
University of KentuckyLexington, KY1$1.5 million0$0
Florida International UniversityMiami, FL3$1.5 million0$0
L2 Diagnostics, LLCNew Haven, CT4$1.5 million0$0
University of Nebraska Medical CenterOmaha, NE1$1.5 million0$0
University of AlbertaEdmonton1$1.5 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025296$150,812,7510$0
2024310$154,917,9840$0
2023307$152,799,0340$0
2022299$148,863,3480$0
2021307$151,331,7330$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 5 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 1 award here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 1 award here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185NIHMay 7, 2027Not listedNotice number printed on 1 award here
Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required)RFA-AI-27-002NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 533 awards here
Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)RFA-AI-27-005NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 533 awards here
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)PAR-25-370NIH93.855November 16, 2026$50,000Same assistance listing 93.855 as 533 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 533 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 533 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.855January 7, 2027Not listedSame assistance listing 93.855 as 533 awards here
HIV/AIDS Clinical Trials Network Leadership and Operations CentersRFA-AI-28-001NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 533 awards here
HIV/AIDS Clinical Trials Network Laboratory CentersRFA-AI-28-002NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 533 awards here
HIV/AIDS Clinical Trials Network Statistical and Data Management CentersRFA-AI-28-003NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 533 awards here
HIV/AIDS Clinical Trials Network Clinical Trials UnitsRFA-AI-28-004NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 533 awards here
Precision and Systems Biology to Uncover the Link Between Chronic and Infectious DiseasesRFA-AI-28-014NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 533 awards here
Immune Tolerance Network (UM1 Clinical Trial Required)RFA-AI-28-005NIH93.855January 29, 2027Not listedSame assistance listing 93.855 as 533 awards here
Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)RFA-AI-28-012NIH93.855January 29, 2027Not listedSame assistance listing 93.855 as 533 awards here
Accelerating Research and Development of Next Generation Vaccines against Malaria - a Model for Mosquito-Borne Diseases (R61/R33 Clinical Trial Not Allowed)RFA-AI-28-024NIH93.855February 11, 2027Not listedSame assistance listing 93.855 as 533 awards here
NLM Institutional Grants for Research Training in Biomedical Informatics, Data Science, and AI (T15 Independent Clinical Trial Not Allowed)RFA-LM-28-001NIH93.855February 11, 2027$775,000Same assistance listing 93.855 as 533 awards here
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)PA-27-100NIH93.855April 5, 2027Not listedSame assistance listing 93.855 as 533 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.