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Data / Research funding / Chronic Fatigue Syndrome (ME/CFS)

Chronic Fatigue Syndrome (ME/CFS): 26 NIH awards ($34M) to 19 organizations

26 NIH awards ($34M) in the NIH spending category Chronic Fatigue Syndrome (ME/CFS), to 19 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

Topic
NIH spending category

Awards

26 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
DMCC for ME/CFS: Recompete 2022 + CDE Admin SupplementNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,108,200September 25, 2017May 31, 2028CARNES, MEGANreporter.nih.gov
Maintenance and Incidence of ME/CFS following MonoNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$3,284,564January 1, 2020November 30, 2025JASON, LEONARD Areporter.nih.gov
A Cardiovascular Analysis of Post-exertional Malaise.NIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,609,705May 1, 2021February 28, 2026NATELSON, BENJAMINreporter.nih.gov
Altered T Cell Responses in Myalgic Enchephalomeylitis/Chronic Fatigue Syndrome (ME/CFS)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,446,878March 8, 2021February 28, 2027SELIN, LIISA KAARINAreporter.nih.gov
Center for Solutions for ME/CFSNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,443,290September 22, 2017August 31, 2024LIPKIN, W. IANreporter.nih.gov
Mechanistic Assessment of N-Acetylcysteine as an Antioxidant Therapy for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Through Dose Response and Treatment Target EngagementNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,274,092July 15, 2020April 30, 2027SHUNGU, DIKOMA Creporter.nih.gov
Human Herpesvirus 6B in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome pathogenesis: temporal analysis of viral reactivation and immunity to elucidate cause vs effectNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,078,193September 9, 2022August 31, 2027CLIFF, JACKIEreporter.nih.gov
Stress effects on virus protein induced inflammation and sickness behaviorNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,049,448April 15, 2010June 30, 2026ARIZA, MARIA-EUGENIAreporter.nih.gov
Long COVID as a putative subtype of chronic fatigue syndromeNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,837,410August 18, 2022July 31, 2027SAXENA, RICHAreporter.nih.gov
Molecular and single-cell immunology of myalgic encephalomyelitis/chronic fatigue syndromeNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,433,385June 15, 2018May 31, 2024DAVIS, RONALD WAYNEreporter.nih.gov
Mechanisms of Cognitive Control Impairment in ME/CFS and PASC-ME/CFSNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,430,688September 1, 2023July 31, 2028ERYILMAZ, H HAMDIreporter.nih.gov
Measuring neuroinflammation in chronic fatigue syndrome with whole-brain magnetic resonance spectroscopyNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,379,796July 1, 2019March 31, 2025YOUNGER, JARRED W.reporter.nih.gov
Cerebral Energy Metabolism in ME/CFS with and without PASCNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,308,958July 1, 2024June 30, 2029XU, XIANGreporter.nih.gov
Evaluating the Epidemiology and Determinants of Neurologic Post-acute Sequelae of SARS-CoV-2NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$753,698August 16, 2022July 31, 2026PURPURA, LAWRENCE JAMESreporter.nih.gov
Proteomic identification of Myalgic encephalomyelitis/chronic fatigue syndromeNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$604,257December 1, 2021August 31, 2022NATELSON, BENJAMINreporter.nih.gov
Structural and Metabolic Neuroimaging of ME/CFS Occurring with and without COVID-19 InfectionNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$464,750March 1, 2022February 28, 2025XU, XIANGreporter.nih.gov
Correlating neutrophil function and plasma cytokine profiles with progression of ME/CFS and Long-Covid/PASCNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$462,000December 5, 2022November 30, 2025ELLETT, FELIXreporter.nih.gov
ATG13: A new player in ME/CFSNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$450,000May 1, 2023April 30, 2025ROY, AVIKreporter.nih.gov
Mechanophenotyping RBC subpopulations in ME/CFSNIHNational Heart, Lung, and Blood Institute2025$432,431January 15, 2025December 31, 2027RAMASUBRAMANIAN, ANAND Kreporter.nih.gov
Imaging inflammation in the whole body and brain of ME/CFS patientsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$431,651December 15, 2020November 30, 2022JAMES, MICHELLE LOUISEreporter.nih.gov
Develop a novel red blood cell-based microfluidic approach to assess and diagnose ME/CFSNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$407,024December 1, 2023October 31, 2026WAN, JIANDIreporter.nih.gov
Development of humanized microbiota mouse models of ME/CFSNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$400,950May 7, 2024March 31, 2027LOMBARDI, VINCENT Creporter.nih.gov
Transcriptional profiling of proliferative skeletal muscle mononucleated cells coupled with broadband electrical cytometry towards diagnosis of myalgic encephalomyelitis/chronic fatigue syndromeNIHNational Institute of Neurological Disorders and Stroke2024$390,178September 4, 2024August 31, 2026CHENG, XUANHONGreporter.nih.gov
Endogenous retrovirus analyses in myalgic encephalomyelitisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$240,821January 19, 2021June 30, 2023LI, DAWEIreporter.nih.gov
MSC exosomes as probes for ME/CSF immune cell dysfunctionNIHNational Institute of Allergy and Infectious Diseases2025$224,070December 1, 2024November 30, 2026BELJANSKI, VLADIMIRreporter.nih.gov
Viral Infection and Inflammation Workshop 2024NIHNational Institute of Allergy and Infectious Diseases2024$7,000July 17, 2024June 30, 2025KURITZKES, DANIEL R.reporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Icahn School of Medicine at Mount SinaiNew York, NY4$5 million0$0
Research Triangle InstituteResearch Triangle Park, NC1$4.1 million0$0
Massachusetts General HospitalBoston, MA3$3.7 million0$0
DePaul UniversityChicago, IL1$3.3 million0$0
Columbia University Health SciencesNew York, NY2$3.2 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA1$2.4 million0$0
Weill Medical Coll of Cornell UnivNew York, NY1$2.3 million0$0
London Sch/hygiene & Tropical MedicineLondon1$2.1 million0$0
Ohio State UniversityColumbus, OH1$2 million0$0
Stanford UniversityStanford, CA2$1.9 million0$0
University of Alabama at BirminghamBirmingham, AL1$1.4 million0$0
Simmaron Research INCIncline Village, NV1$450,0000$0
San Jose State University FoundationSan Jose, CA1$432,4310$0
University of California at DavisDavis, CA1$407,0240$0
Board of Regents, NSHE, obo University of Nevada, RenoReno, NV1$400,9500$0
Lehigh UniversityBethlehem, PA1$390,1780$0
Florida Atlantic UniversityBoca Raton, FL1$240,8210$0
Nova Southeastern UniversityFort Lauderdale-Davie, FL1$224,0700$0
Brigham and Women's HospitalBoston, MA1$7,0000$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
202512$5,710,6470$0
202416$6,474,8440$0
202314$6,917,3810$0
202216$6,621,2520$0
202112$8,229,3130$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Functional Target Validation for Alzheimer's Disease-Related DementiasRFA-NS-26-034NIH93.853November 6, 2026Not listedSame assistance listing 93.853 as 13 awards here
Clinical Trials and Ancillary Studies Conducted within NIH-Funded Clinical Trial Research Networks (UG3/UH3 - Clinical Trial Required)PAR-27-007NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 13 awards here
Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)RFA-NS-26-001NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 13 awards here
Genomic and Biologic Therapies for ADRD (U01 Clinical Trial Optional)RFA-NS-26-030NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 13 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.853November 18, 2026Not listedSame assistance listing 93.853 as 13 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.853November 18, 2026Not listedSame assistance listing 93.853 as 13 awards here
NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional)PAR-25-052NIH93.853November 19, 2026Not listedSame assistance listing 93.853 as 13 awards here
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)RFA-AT-25-003NIH93.853November 23, 2026$375,000Same assistance listing 93.853 as 13 awards here
Maximizing the Scientific Value of Data Generated by the Environmental Influences on Child Health Outcomes (ECHO) Program: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (F32)RFA-OD-27-008NIH93.853December 2, 2026Not listedSame assistance listing 93.853 as 13 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIH93.853December 3, 2026Not listedSame assistance listing 93.853 as 13 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIH93.853December 3, 2026Not listedSame assistance listing 93.853 as 13 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.853December 4, 2026Not listedSame assistance listing 93.853 as 13 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.853January 7, 2027$375,000Same assistance listing 93.853 as 13 awards here
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)RFA-NS-25-023NIH93.853January 15, 2027$350,000Same assistance listing 93.853 as 13 awards here
HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)RFA-DA-28-011NIH93.853January 26, 2027Not listedSame assistance listing 93.853 as 13 awards here
HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) - Building Engagement, Assistance, Capacity, Outreach, and Networks (BEACON) Center (U2C Clinical Trial Not Allowed)RFA-DA-28-012NIH93.853January 26, 2027Not listedSame assistance listing 93.853 as 13 awards here
Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)PAR-24-268NIH93.853January 27, 2027$500,000Same assistance listing 93.853 as 13 awards here
Translational Neural Devices (R61/R33 - Clinical Trial Optional)PAR-25-053NIH93.853January 28, 2027Not listedSame assistance listing 93.853 as 13 awards here
BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)RFA-NS-24-031NIH93.853January 28, 2027$750,000Same assistance listing 93.853 as 13 awards here
BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous SystemRFA-NS-28-006NIH93.853January 28, 2027Not listedSame assistance listing 93.853 as 13 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.