Data / Research funding / South Dakota
South Dakota: 78 NIH awards ($137.9M) and 172 NSF awards ($107.1M) to 21 organizations
Organizations in South Dakota hold 78 NIH awards ($137.9M) and 172 NSF awards ($107.1M) from NIH and NSF, across 21 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025; NSF fiscal years 2022 to 2026.
SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.
- South DakotaState
Largest awards
250 awards in the window.
| Award | Agency | Institute or division | Fiscal year | Amount in window | Start | End | Principal investigator | Source |
|---|---|---|---|---|---|---|---|---|
| SD INBRE Administrative Supplement Extension | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $21,789,824 | September 24, 2001 | August 31, 2026 | HUBER, VICTOR CHESTER | reporter.nih.gov |
| Environmental influences on Child Health Outcomes in the Northern Plains PASS-ECHO Cohort | NIH | Office of the Director, National Institutes of Health | 2021 to 2025 | $13,912,786 | September 21, 2016 | May 31, 2030 | ELLIOTT, AMY J | reporter.nih.gov |
| Environmental influences on Child Health Outcomes in the Northern Plains PASS-ECHO Cohort | NIH | Office of the Director, National Institutes of Health | 2023 to 2024 | $12,584,157 | September 21, 2016 | May 31, 2025 | ELLIOTT, AMY J | reporter.nih.gov |
| BioSystems Networks and Translational Research - Insights into Inflammation (BioSNTR-II) | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $9,245,870 | March 20, 2022 | January 31, 2027 | HOPPE, ADAM DAVID | reporter.nih.gov |
| STRONG HEART STUDY (SHS)- FIELD CENTER, TASK ORDER 001 | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $5,867,487 | February 15, 2019 | February 14, 2026 | FRETTS, AMANDA MAE | reporter.nih.gov |
| Collaborative Research: E-CORE RII: South Dakota Research Ecosystem Network: Advancing STEM Education | NSF | Office of Integrative Activities | 2024 | $5,237,817 | May 15, 2024 | April 30, 2028 | Bentley Sayler | nsf.gov |
| Center for Pediatric Research | NIH | National Institute of General Medical Sciences | 2021 to 2023 | $5,110,350 | September 1, 2013 | August 31, 2025 | ROUX, KYLE J | reporter.nih.gov |
| ExpandQISE: Track 2: Quantum Materials Institute: 2D Materials, heterostructures and metasurfaces for compact, efficient entangled photon-pair generation for quantum communications | NSF | MPS - Core Programs | 2024 | $5,000,000 | October 1, 2024 | September 30, 2029 | Steve Smith | nsf.gov |
| Sanford Community Cancer Program of the North Central Plains (NCORP) | NIH | National Cancer Institute | 2021 to 2025 | $4,994,838 | August 12, 2014 | July 31, 2026 | MILANOVICH, SAMUEL J. | reporter.nih.gov |
| Collaborative Research: E-RISE RII: BioNitrogen Economy Research Center | NSF | Office of Integrative Activities | 2024 | $4,518,777 | August 1, 2024 | July 31, 2028 | Ruanbao Zhou | nsf.gov |
| Maternal American-Indian Rural Community Health (MARCH) | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $4,473,717 | August 17, 2023 | July 31, 2030 | ELLIOTT, AMY J | reporter.nih.gov |
| Lakota Center for Health Research | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $4,073,634 | September 1, 2022 | July 31, 2027 | HENDERSON, JEFFREY A | reporter.nih.gov |
| RII Track-2 FEC: Advancement of Microbial Technologies for Sustainable Agriculture | NSF | Office of Integrative Activities | 2023 | $4,000,000 | August 1, 2023 | July 31, 2027 | Srinivas Janaswamy | nsf.gov |
| Center for Cancer Biology Research | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $3,735,000 | April 1, 2023 | February 29, 2028 | MISKIMINS, W KEITH | reporter.nih.gov |
| SFS AI + Cybersecurity: Preparing the Next Generation of Public Professionals in Artificial Intelligence and Cybersecurity | NSF | Scholarships, Fellowships, and Traineeships Section | 2025 | $3,596,628 | August 15, 2025 | July 31, 2028 | Michael Ham | nsf.gov |
| NRT: Training Scientists to Solve Biofilm Challenges Using Artificial Intelligence and Smart Materials | NSF | Scholarships, Fellowships, and Traineeships Section | 2025 | $3,025,000 | September 1, 2025 | August 31, 2030 | Venkataramana Gadhamshetty | nsf.gov |
| Collaborative Research: RII FEC: Advancing Quality and Climate-Resilient Water Management with Community Partnerships and Enhanced Sensor Network | NSF | Office of Integrative Activities | 2024 | $2,674,086 | August 1, 2024 | July 31, 2028 | Venkataramana Gadhamshetty | nsf.gov |
| TEA Center: Kaksiza Caŋhdeṡka Center for Dakota Linguistics | NSF | Education Capacity Building & Transformation Section | 2022 | $2,500,000 | December 1, 2021 | November 30, 2027 | Alessandro M Jaker | nsf.gov |
| ICE-TI: Addressing the Socio-Economic needs of the Sisseton Wahpeton Oyate with a bachelor's of science in Behavioral Sciences | NSF | Education Capacity Building & Transformation Section | 2022 | $2,499,999 | May 15, 2022 | April 30, 2028 | Julie K Buckman | nsf.gov |
| Center for Pediatric Research | NIH | National Institute of General Medical Sciences | 2024 to 2025 | $2,484,391 | July 1, 2024 | June 30, 2029 | ROUX, KYLE J | reporter.nih.gov |
| ICE-TI: Maka Kin Awayankapi (Stewards of Earth) | NSF | Education Capacity Building & Transformation Section | 2025 | $2,300,000 | June 1, 2025 | May 31, 2030 | Camille L Griffith | nsf.gov |
| PTSD, AUD, and Interpersonal Conflict: Within-person associations | NIH | National Institute of Mental Health | 2021 to 2024 | $2,272,458 | July 1, 2020 | April 30, 2026 | SIMONS, JEFFREY S | reporter.nih.gov |
| Transdisciplinary approaches to American Indian and rural population health research | NIH | National Institute of General Medical Sciences | 2022 | $2,242,375 | July 1, 2017 | December 31, 2024 | WEIMER, JILL M | reporter.nih.gov |
| Collaborative Research: FEC: Establishing Infrastructure for AI-Driven Discovery of Small Molecules to Combat Antibiotic Resistance, Biofilms, and Aflatoxin Contamination | NSF | Office of Integrative Activities | 2025 | $2,190,786 | August 15, 2025 | July 31, 2029 | Nicholas C Butzin | nsf.gov |
| South Dakota Pediatric Clinical Trials Network (SoDakPCTN) | NIH | Office of the Director, National Institutes of Health | 2021 to 2025 | $2,075,669 | September 1, 2020 | May 31, 2030 | ANGAL, JYOTI | reporter.nih.gov |
| ICE-TI: Thokatakiya (Towards the future) | NSF | Education Capacity Building & Transformation Section | 2023 | $2,000,000 | April 15, 2023 | March 31, 2028 | Charles J Tinant | nsf.gov |
| Scholarships for Academy of Next-Generation Leaders in Engineering and Science | NSF | Scholarships, Fellowships, and Traineeships Section | 2025 | $2,000,000 | October 1, 2025 | September 30, 2030 | Suzette R Burckhard | nsf.gov |
| Research-based Interventions for Engaging Low-Income Undergraduates in STEM | NSF | Scholarships, Fellowships, and Traineeships Section | 2026 | $2,000,000 | February 1, 2027 | January 31, 2033 | Daniel J Asunskis | nsf.gov |
| Supporting Masters Biotechnology Scholars to Serve Regional STEM Workforce Needs | NSF | Scholarships, Fellowships, and Traineeships Section | 2025 | $1,999,742 | July 1, 2025 | June 30, 2030 | Mark Brown | nsf.gov |
| EPSCoR Graduate Fellowship Program (EGFP): Enhancing Development of Innovative Materials for Agriculture, Human Health, and Quantum Science | NSF | Scholarships, Fellowships, and Traineeships Section | 2025 | $1,908,000 | July 15, 2025 | June 30, 2028 | Maribeth H Price | nsf.gov |
| Trophic Factors in Cognition | NIH | National Institute of Mental Health | 2021 to 2025 | $1,867,708 | February 11, 2016 | December 31, 2026 | SATHYANESAN, SAMUEL NEWTON | reporter.nih.gov |
| Molecular and cellular basis of the renal diseases associated with Alagille Syndrome | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $1,811,392 | May 1, 2021 | February 28, 2027 | SURENDRAN, KAMESWARAN | reporter.nih.gov |
| Cardiac Pathophysiology of Proteasome Phosphoregulation | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $1,800,966 | September 1, 2020 | April 30, 2029 | WANG, XUEJUN | reporter.nih.gov |
| Factors Influencing Pediatric Asthma into Adulthood (FIPA2) | NIH | National Institute on Minority Health and Health Disparities | 2023 to 2025 | $1,740,885 | September 25, 2023 | April 30, 2028 | BEST, LYLE G | reporter.nih.gov |
| Dietary interventions to modulate heart health in offspring born to diabetic mothers and the subsequent generation. | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $1,660,000 | January 15, 2022 | December 31, 2026 | BAACK, MICHELLE LEIGH | reporter.nih.gov |
| Genetic analyses of molybdenum cofactor biology | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $1,660,000 | September 1, 2022 | June 30, 2027 | WARNHOFF, KURT | reporter.nih.gov |
| Priming the proteasome to protect against aging and Alzheimer's disease | NIH | National Institute on Aging | 2022 | $1,625,919 | July 1, 2022 | June 30, 2025 | WANG, XUEJUN | reporter.nih.gov |
| Collaborative Research: E-RISE RII: Germanium-based Science and Technology Advancement Research | NSF | Office of Integrative Activities | 2025 | $1,562,289 | July 1, 2025 | June 30, 2029 | Dongming Mei | nsf.gov |
| Research-based Interventions for STEM Engagement | NSF | Scholarships, Fellowships, and Traineeships Section | 2022 | $1,499,928 | February 1, 2023 | January 31, 2029 | Daniel J Asunskis | nsf.gov |
| The immune regulation of macrophage antibody dependent cellular phagocytosis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $1,490,240 | July 10, 2020 | April 30, 2026 | HOPPE, ADAM DAVID | reporter.nih.gov |
| Uncovering cargo and cell type specific molecular mechanisms of renal tubular epithelial transport | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $1,484,250 | September 15, 2022 | April 30, 2027 | CHANDRASEKAR, INDRA | reporter.nih.gov |
| PKG and PKA Duo-Activation to Treat Cardiac Proteotoxicity | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,446,719 | July 1, 2003 | June 30, 2026 | WANG, XUEJUN | reporter.nih.gov |
| Equipment: MRI: Track 1 Acquisition of a Scanning Transmission Electron Microscope for Materials Research at the South Dakota School of Mines and Technology | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $1,398,445 | August 1, 2024 | July 31, 2027 | SHAN ZHOU | nsf.gov |
| Intra-tumoral neurons contribute to head and neck cancer pain | NIH | National Institute of Dental & Craniofacial Research | 2023 to 2025 | $1,375,081 | April 1, 2023 | March 31, 2028 | VERMEER, PAOLA DRAPKIN | reporter.nih.gov |
| CAREER: Mechanisms and drivers underlying thermal specialization patterns in elastic recoil and muscle powered movements | NSF | Cell Development & Physiology | 2022 | $1,287,864 | July 1, 2022 | June 30, 2027 | Christopher V Anderson | nsf.gov |
| Transcriptional regulation of neural progenitor divisions and cell fate in the developing cortex | NIH | National Institute of Mental Health | 2023 to 2025 | $1,245,000 | August 15, 2023 | May 31, 2028 | PILAZ, LOUIS-JAN | reporter.nih.gov |
| Identifying regulatory networks that govern primary cilia remodeling and neural signaling | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $1,245,000 | August 1, 2023 | May 31, 2028 | LOUKIL, ABDELHALIM | reporter.nih.gov |
| CAREER: The interaction of deficits in cellular regulation and divergent parental environments to postzygotic isolation in hybridizing milkweeds (Asclepias) | NSF | Infrastructure, Institutes, & Centers | 2023 | $1,212,093 | June 15, 2023 | May 31, 2028 | Carrie F Olson-Manning | nsf.gov |
| A Mobile Web App Intervention to Promote Cervical Cancer Screening among Indigenous Women | NIH | National Cancer Institute | 2024 to 2025 | $1,196,713 | September 1, 2024 | August 31, 2028 | ROH, SOONHEE | reporter.nih.gov |
| Oncogenic mechanism of Sox2 in Rb-deficient tumors | NIH | National Cancer Institute | 2021 to 2023 | $1,124,765 | July 23, 2019 | June 30, 2025 | KARETA, MICHAEL S. | reporter.nih.gov |
| Targeting HIV Myeloid Reservoirs in the CNS by IAP and TREM1 Inhibition | NIH | National Institute of Mental Health | 2023 to 2025 | $1,121,250 | December 1, 2022 | April 30, 2027 | CAMPBELL, GRANT R | reporter.nih.gov |
| MRI: Track 1 Acquisition of Nexsa G2 XPS Surface Analysis System | NSF | Civil, Mechanical, & Manufacturing Innovation | 2023 | $1,097,251 | September 1, 2023 | August 31, 2026 | Alevtina White Smirnova | nsf.gov |
| Community Based System Dynamics Models of Alcohol and Substance Exposed Pregnancy in Northern Plains American Indian Women | NIH | National Institute on Drug Abuse | 2021 to 2023 | $1,078,186 | October 1, 2020 | May 31, 2025 | DEUTSCH, ARIELLE R. | reporter.nih.gov |
| Collaborative Research: E-RISE RII: BioNitrogen Economy Research Center | NSF | Office of Integrative Activities | 2024 | $1,054,895 | August 1, 2024 | July 31, 2028 | Nick J Klein | nsf.gov |
| CAREER: Bacterial heterogeneity in stress survival | NSF | Cell Development & Physiology | 2023 | $1,045,632 | April 1, 2023 | March 31, 2028 | Nicholas C Butzin | nsf.gov |
| G-RISE University of South Dakota | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $1,018,930 | May 1, 2020 | April 30, 2026 | BURRELL, BRIAN DONALD | reporter.nih.gov |
| CPS-CIR, CPS-FR: HiddenObjects: Physics-Guided Latent Space Models for Detecting Occluded Objects | NSF | Cyber, Physical, & Intelligent Systems | 2026 | $1,000,000 | September 1, 2026 | August 31, 2030 | Shabbir Ahmed | nsf.gov |
| RII-BEC: Grounding Science Education in Indigenous Knowledges, Food Systems, and Sustainability | NSF | Office of Integrative Activities | 2022 | $999,976 | September 1, 2022 | August 31, 2027 | Meghann E Jarchow | nsf.gov |
| RCN:CIP: A Connect.CI-based Community-Wide Mentorship Network (CCMnet) for the Advancement of Science and Engineering Research and Education | NSF | Office of Advanced Cyberinfrastructure | 2022 | $999,797 | January 1, 2023 | December 31, 2027 | Rajesh Kavasseri | nsf.gov |
| CC* Regional: SD-REDI: The South Dakota Research and Education Data Interchange | NSF | Office of Advanced Cyberinfrastructure (OAC) | 2022 | $998,750 | July 1, 2022 | June 30, 2025 | Liza Clark | nsf.gov |
| Beginnings: Dakota Biotechnology Rural Workforce Development Program | NSF | Workforce and Capacity Building Section | 2025 | $998,061 | October 1, 2025 | September 30, 2028 | Mark Brown | nsf.gov |
| Building a Sense of Belonging for Talented, Low-Income Students through Engagement | NSF | Scholarships, Fellowships, and Traineeships Section | 2023 | $996,266 | October 15, 2023 | September 30, 2029 | Richard I Avery | nsf.gov |
| Collaborative Research: RII FEC: Harnessing Controlled Environment Agriculture to Secure Sustainability and Economic Growth | NSF | Office of Integrative Activities | 2024 | $991,072 | September 1, 2024 | August 31, 2028 | Meghann E Jarchow | nsf.gov |
| MRI: Acquisition of a Heterogeneous High-Performance Computing Cluster Driven by Computational and Data-Intensive Multidisciplinary Research | NSF | Office of Advanced Cyberinfrastructure (OAC) | 2022 | $978,708 | October 1, 2022 | September 30, 2025 | Kevin L Brandt | nsf.gov |
| Collaborative Research: E-RISE RII: Germanium-based Science and Technology Advancement Research | NSF | Office of Integrative Activities | 2025 | $932,864 | July 1, 2025 | June 30, 2029 | Xinhua Bai | nsf.gov |
| CAREER: Discovery of Composition-Enriched Cosmic Ray Anisotropy with the IceCube Neutrino Observatory | NSF | Physics Section | 2025 | $900,000 | July 1, 2025 | June 30, 2030 | Matthias Plum | nsf.gov |
| Evolution and application of proximity protein labeling | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $820,000 | September 1, 2018 | February 28, 2025 | ROUX, KYLE J | reporter.nih.gov |
| Collaborative Research: FEC: Establishing Infrastructure for AI-Driven Discovery of Small Molecules to Combat Antibiotic Resistance, Biofilms, and Aflatoxin Contamination | NSF | Office of Integrative Activities | 2025 | $809,743 | August 15, 2025 | July 31, 2029 | Rajesh K Sani | nsf.gov |
| ExpandQISE: Track 1: Ferroelectric Ordering and Polarization-Coupled Transport Properties in 2D Van der Waals Materials | NSF | MPS - Core Programs | 2023 | $800,000 | October 1, 2023 | September 30, 2027 | Alexey Lipatov | nsf.gov |
| EPSCoR Graduate Fellowship Program (EGFP): IMPACTS - Integrating Mentorship and Practice to Advance Careers in Technology & Science | NSF | Scholarships, Fellowships, and Traineeships Section | 2026 | $795,000 | March 15, 2027 | February 28, 2030 | Randolph S Faustino | nsf.gov |
| Collaborative Research: RII Track-2 FEC: STORM: Data-Driven Approaches for Secure Electric Grids | NSF | Office of Integrative Activities | 2023 | $750,000 | September 15, 2023 | August 31, 2027 | Kwanghee Won | nsf.gov |
| Dual Effects of Endocannabinoid Modulation in Nociception | NSF | Cell Development & Physiology | 2024 | $750,000 | July 1, 2024 | June 30, 2027 | Brian Burrell | nsf.gov |
| Biological vector borne transmission of Salmonella by cockroaches | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $749,279 | November 1, 2022 | November 2, 2024 | PIETRI, JOSE ENRIQUE | reporter.nih.gov |
| FOXOs in ischemic stroke | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2023 | $747,292 | May 15, 2022 | June 30, 2023 | WANG, HONGMIN | reporter.nih.gov |
| Influence of early developmental ethanol exposure on genes, the mTOR signaling pathway and behavior | NIH | National Institute on Alcohol Abuse and Alcoholism | 2021 to 2023 | $747,000 | September 10, 2021 | August 31, 2025 | FERNANDES, YOHAAN M | reporter.nih.gov |
| CER: Helping Adults Make Safe and Informed Decisions About Artificial Intelligence Across the Lifespan | NSF | Human Centered Computing & Education | 2026 | $726,518 | October 1, 2026 | September 30, 2029 | Taher Deemyad | nsf.gov |
| The role of pro-BDNF/mature-BDNF balance in skeletal muscle inactivity-induced capillary regression | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $725,128 | July 1, 2019 | December 31, 2024 | LI, YIFAN | reporter.nih.gov |
| Collaborative Research: Costs and Trade-offs of Phenotypically Flexible Responses to Winter Temperature Variability in Birds | NSF | Infrastructure, Institutes, & Centers | 2023 | $693,863 | May 1, 2023 | April 30, 2027 | David L Swanson | nsf.gov |
| An interactive tool for in-depth and reproducible analysis of RNA-seq data | NIH | National Human Genome Research Institute | 2021 to 2023 | $689,557 | September 2, 2020 | June 30, 2025 | GE, XIJIN | reporter.nih.gov |
| Equipment: MRI: Track 1 Acquisition of Microbioreactor for Advancing Biological, Environmental, and Biomanufacturing Research | NSF | Infrastructure, Institutes, & Centers | 2025 | $687,304 | September 15, 2025 | August 31, 2028 | TANVI GOVIL | nsf.gov |
| Collaborative Research: An Integrative Approach To Examine Freshwater Mussel Physiological Responses to Multiple Stressors | NSF | Cell Development & Physiology | 2026 | $658,292 | January 1, 2027 | December 31, 2030 | Omera B Matoo | nsf.gov |
| CAREER: Determining the Metabolic Organization and Enzymology of the Fundamentally Important Flavonoid Biosynthetic Pathway | NSF | Cell Development & Physiology | 2024 | $644,302 | February 15, 2024 | February 28, 2027 | Daniel K Owens | nsf.gov |
| CONNECT TASK ORDER 8 | NIH | National Cancer Institute | 2024 | $594,940 | September 27, 2024 | September 19, 2025 | CHUN-HUNG, CHAN | reporter.nih.gov |
| Elucidating spatiotemporal dynamics of nascent extracellular matrix in response to platinum treatment in ovarian cancer | NIH | National Cancer Institute | 2025 | $584,081 | May 12, 2025 | April 30, 2030 | DE LA PUENTE, PILAR | reporter.nih.gov |
| CAREER: Determining and Tuning the Impact of Low-Level Metal-Based Nanoparticles on Actin Cytoskeleton in Normal and Cancer Cells | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2022 | $575,725 | February 1, 2022 | January 31, 2027 | Steve Smith | nsf.gov |
| Assessing the paleoenvironmental and geobiological significance of carbonates from the Eocene-Oligocene boundary of the White River Group | NSF | GEO - Core Programs | 2023 | $563,380 | January 1, 2024 | December 31, 2027 | Sarah W Keenan | nsf.gov |
| CAREER: Parahydrogen-Induced Polarization (PHIP) of Nitrogen as a Path to Metabolic Sensing and Breakthroughs in Fundamental Science | NSF | Chemistry Section | 2026 | $559,325 | August 1, 2026 | July 31, 2031 | Roman Shchepin | nsf.gov |
| CAREER: The Contagion Science: Integration of inhaled transport mechanics principles inside the human upper respiratory tract at multi scales | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $557,486 | January 1, 2024 | December 31, 2028 | Saikat Basu | nsf.gov |
| CAREER: Data-Driven Prioritization and Control of Disinfection Byproducts in Drinking Water | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2025 | $550,000 | September 1, 2025 | December 31, 2025 | Tao Ye | nsf.gov |
| MRI: Acquisition of a nanoIR3 for Polymers and Life Science Research | NSF | Division of Biological Infrastructure | 2022 | $548,158 | September 1, 2022 | August 31, 2025 | Rajesh K Sani | nsf.gov |
| Investigating environmental identity development among children in rural Alaska Native communities through intergenerational, culturally responsive community science programming | NSF | Division of Research on Learning in Formal and Informal Settings (DRL) | 2022 | $538,911 | February 1, 2022 | January 31, 2025 | Carie J Green | nsf.gov |
| NSFGEO-NERC: Carbon concentration and variability in Earth’s mantle | NSF | GEO - Core Programs | 2026 | $536,839 | March 15, 2026 | February 28, 2029 | Gokce K Ustunisik | nsf.gov |
| Assessing the Strength of Weak Ties | NIH | National Institute of General Medical Sciences | 2025 | $533,726 | September 20, 2019 | July 31, 2028 | CHAKRAVARTY, SUVOBRATA | reporter.nih.gov |
| CAREER: Evaluating models of intracratonic structural reactivation: A case study of the Black Hills, western South Dakota | NSF | GEO - Core Programs | 2025 | $519,681 | June 1, 2025 | May 31, 2030 | Trevor S Waldien | nsf.gov |
| Probing the mechanisms of dependency underlying skeletal genetic pathways of p53 and Notch in the pathogenesis of osteosarcoma | NIH | National Cancer Institute | 2025 | $514,405 | April 1, 2025 | March 31, 2030 | TAO, JIANNING | reporter.nih.gov |
| CAS: Tuning Deoxyfluorination Reactivity and Selectivity by Coherently Modulating Fluoride-pi Interaction Strength, SNAr Kinetics, and Leaving Group Ability | NSF | Chemistry Section | 2023 | $512,777 | July 1, 2023 | June 30, 2027 | Haoran Sun | nsf.gov |
| Priming the proteasome to protect against aging and Alzheimer's disease | NIH | National Institute on Aging | 2025 | $507,242 | July 1, 2022 | June 30, 2027 | WANG, XUEJUN | reporter.nih.gov |
| Developing a blood fatty acid-based algorithm as an early predictor of cognitive decline and dementia: Applying machine learning to harmonized data from prospective cohort studies | NIH | National Institute on Aging | 2024 | $506,500 | December 1, 2023 | November 30, 2025 | HARRIS, BILL | reporter.nih.gov |
| CPS: Small: Cybersickness Mitigation and Test Suite Development | NSF | Cyber, Physical, & Intelligent Systems | 2022 | $502,844 | October 1, 2022 | May 31, 2027 | Lisa R Rebenitsch | nsf.gov |
| FMSG: Bio: RAMP-Bio-CAFe: Routing Advanced Manufacturing of BioPolymer(s): Capturing Agri-feedstocks in Cell free Factories | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $500,000 | October 1, 2023 | September 30, 2027 | TANVI GOVIL | nsf.gov |
| Research Infrastructure: CC* Campus Compute: Lawrence 2.0: Advancing Multi-Disciplinary Research and Education in South Dakota | NSF | Office of Advanced Cyberinfrastructure | 2024 | $499,920 | July 1, 2024 | June 30, 2027 | Ryan M Johnson | nsf.gov |
| Equipment: MRI: Track 1 Acquisition of an Illumina NextSeq 2000 to Support Genomics Research and Training Capacity in South Dakota | NSF | Infrastructure, Institutes, & Centers | 2026 | $495,290 | August 1, 2026 | July 31, 2029 | Shyam Solanki | nsf.gov |
| BRC-BIO: Towards mechanistic elucidation of wall-associated kinase immunity receptors in barley-spot blotch interaction | NSF | Infrastructure, Institutes, & Centers | 2024 | $494,829 | August 1, 2024 | July 31, 2027 | Gazala Ameen | nsf.gov |
| Collaborative Research: The great Alaskan escape room: Has Northern Cordilleran escape tectonics fluctuated with time and why? | NSF | GEO - Core Programs | 2022 | $487,091 | August 1, 2022 | July 31, 2026 | Trevor S Waldien | nsf.gov |
| Aptamers as Novel Inhibitors of the Neurotoxin Beta-methylamino-L-alanine (BMAA) | NIH | National Institute of Environmental Health Sciences | 2025 | $484,122 | August 20, 2025 | July 31, 2028 | PAWLUS, MATTHEW RYAN | reporter.nih.gov |
| Neurotrophic Drug Development for Alzheimer's Disease | NIH | National Institute on Aging | 2025 | $475,014 | September 22, 2025 | March 22, 2027 | SATHYANESAN, SAMUEL NEWTON | reporter.nih.gov |
| Data-Driven Discovery of Governing Equations for Multidimensional Engineering Systems | NSF | Civil, Mechanical, & Manufacturing Innovation | 2026 | $473,503 | October 1, 2026 | September 30, 2029 | Randy C Hoover | nsf.gov |
| REU Site: Back to the Future - Metallurgical and Materials Engineering Summer Program | NSF | Engineering Education Centers | 2025 | $458,070 | September 1, 2025 | August 31, 2028 | Michael K West | nsf.gov |
| REU Site: Black Hills Applied Ceramic Engineering | NSF | GEO - Core Programs | 2024 | $457,223 | September 1, 2024 | August 31, 2027 | Katrina J Donovan | nsf.gov |
| BRC-BIO: Mechanistic regulation of dynamic gene expression patterns by temporal JNK activation | NSF | Infrastructure, Institutes, & Centers | 2025 | $452,892 | May 1, 2025 | April 30, 2028 | Ryan L Hanson | nsf.gov |
| BRC-BIO: Advancing Conservation Paleobiology through Ecometrics: Integrating Functional Traits and Environments of Past, Present, and Future Faunas | NSF | Infrastructure, Institutes, & Centers | 2024 | $452,670 | June 1, 2024 | May 31, 2027 | Rachel A Short | nsf.gov |
| REU Site: Pioneering Opportunities Within Energy & Resource Systems for Undergraduate Research (POWER-UP) | NSF | Engineering Education Centers | 2025 | $451,379 | January 1, 2026 | December 31, 2028 | Jeffrey Doom | nsf.gov |
| REU site: Lithium Sustainability, Mining, Recycling, and Technology (Li-SMART) | NSF | Chemistry Section | 2025 | $450,000 | May 1, 2025 | April 30, 2028 | Fan Zheng | nsf.gov |
| Understanding the role of microbial nanowires as a biosensing tool for peptide detection | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2026 | $450,000 | September 1, 2026 | August 31, 2029 | Saurabh Dhiman | nsf.gov |
| Collaborative Research: Mechanisms to explain continental scaling of size spectra in freshwater streams. | NSF | Organismal Interactions & Ecology | 2025 | $444,570 | January 1, 2026 | December 31, 2028 | Jeff Wesner | nsf.gov |
| Strategy for Safe Colon-targeted Local Therapy of Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $441,111 | September 22, 2021 | June 30, 2025 | TUMMALA, HEMACHAND | reporter.nih.gov |
| Collaborative Research: Facility: Next Generation Interoperable Data Infrastructure for Geoscience Sample Data | NSF | GEO - Core Programs | 2022 | $436,082 | August 15, 2022 | July 31, 2027 | Gokce K Ustunisik | nsf.gov |
| An interactive and reproducible tool for enrichment analysis | NIH | National Human Genome Research Institute | 2024 to 2025 | $429,102 | September 16, 2024 | June 30, 2029 | GE, XIJIN | reporter.nih.gov |
| Sex Differences in the Neurobiological Significance of Orexin Stress Signaling | NIH | National Institute of Mental Health | 2021 | $427,255 | July 1, 2021 | June 30, 2025 | SUMMERS, CLIFF H | reporter.nih.gov |
| Collaborative Research: NSFGEO-NERC: Recent changes in Arctic biogenic sulfur aerosol from a central Greenland ice core | NSF | Office of Polar Programs | 2023 | $424,310 | April 1, 2023 | March 31, 2027 | Jihong Cole-Dai | nsf.gov |
| Role of extracellular matrix remodeling on high-grade serous ovarian carcinoma immune evasion | NIH | National Cancer Institute | 2022 to 2023 | $422,948 | April 1, 2022 | March 31, 2025 | DE LA PUENTE, PILAR | reporter.nih.gov |
| Collaborative Research: RESEARCH-PGR: Deconstructing Plasticity in Perennial Plants: Genomic and Epigenomic Architecture of Scion and Rootstock Traits in Grafted Grapevines | NSF | Innovation Tools, Informatics, & Functional Genomics | 2025 | $419,348 | February 15, 2025 | January 31, 2029 | Anne Fennell | nsf.gov |
| Structure and Function Studies of GPCRome | NIH | National Institute of General Medical Sciences | 2025 | $415,000 | July 1, 2025 | June 30, 2030 | MASUHO, IKUO | reporter.nih.gov |
| Reversing epithelial-mesenchymal transition in metastatic cancer cells using engineered nanomaterials and a mild photothermal effect | NIH | National Cancer Institute | 2022 | $413,479 | September 1, 2022 | August 31, 2025 | WANG, CONGZHOU | reporter.nih.gov |
| Novel methods to improve the utility of genomics summary statistics | NIH | National Human Genome Research Institute | 2023 | $412,245 | September 19, 2023 | August 31, 2025 | TINTLE, NATHAN L | reporter.nih.gov |
| Neural mechanisms of ASH1L in autism spectrum disorder | NIH | National Institute of Mental Health | 2023 | $411,125 | July 15, 2023 | July 14, 2025 | QIN, LUYE | reporter.nih.gov |
| Surveillance of wildlife and livestock for novel and emerging coronaviruses | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $408,375 | July 1, 2021 | June 30, 2023 | NELSON, ERIC A | reporter.nih.gov |
| Collaborative Research: Understanding the influence of tectonic setting on the depth of magmatic processes in the mid-ocean ridge system | NSF | GEO - Core Programs | 2022 | $405,037 | February 1, 2022 | January 31, 2027 | Gokce K Ustunisik | nsf.gov |
| Collaborative Research: Impacts of Organic Nitrogen Dynamics in the Vadose Zone on Groundwater Quality | NSF | GEO - Core Programs | 2026 | $397,098 | August 1, 2026 | July 31, 2029 | Rajesh K Sani | nsf.gov |
| CAREER: Fast-Charging Energy Storage Devices Enabled by Modulating Internal Electric Field of Heterostructure | NSF | Division of Electrical, Communications and Cyber Systems | 2022 | $396,608 | April 1, 2022 | September 30, 2022 | Yue Zhou | nsf.gov |
| Commercializing iDEP, an interactive and reproducible tool for analyzing RNA-Seq data | NIH | National Human Genome Research Institute | 2025 | $395,316 | September 4, 2025 | August 31, 2026 | GE, XIJIN | reporter.nih.gov |
| Collaborative Research: The saboteur's tools in action: cytoplasmic incompatibility genes of the bacterial arthropod symbiont Cardinium hertigii | NSF | Cell Development & Physiology | 2025 | $384,104 | June 1, 2025 | July 31, 2028 | Stephan Schmitz-Esser | nsf.gov |
| A design strategy to quantify unconjugated Nedd8 using genetically encoded sensors. | NIH | National Institute of General Medical Sciences | 2024 | $383,091 | September 1, 2024 | August 31, 2027 | CHOI, YUN SEOK | reporter.nih.gov |
| REU Site in Cellular and Molecular Biology at Sanford Research | NSF | Infrastructure, Institutes, & Centers | 2023 | $378,652 | February 1, 2024 | January 31, 2028 | Lance Lee | nsf.gov |
| Collaborative Research: Assessing current and future dust flux from the Northern Great Plains, U.S. with extreme climate variability and insights from the 1930s Dust Bowl drought | NSF | GEO - Core Programs | 2025 | $377,096 | June 1, 2025 | May 31, 2028 | Mark R Sweeney | nsf.gov |
| Culturally Responsive Palliative Care Messaging for American Indians: An Efficacy Trial | NIH | National Institute of Nursing Research | 2022 to 2023 | $368,794 | September 23, 2022 | January 31, 2025 | ISAACSON, MARY J | reporter.nih.gov |
| REU Site: Back to the Future | NSF | Division Of Materials Research | 2022 | $360,723 | March 1, 2022 | February 28, 2026 | Michael K West | nsf.gov |
| ATD: Development of Statistical Methods for Detection and Characterization of Latent Subpopulations of Classes | NSF | Mathematical Science Section | 2024 | $350,796 | September 1, 2024 | August 31, 2027 | Semhar Michael | nsf.gov |
| REU Site: Molecules Meet Materials | NSF | Chemistry Section | 2022 | $349,990 | June 1, 2022 | May 31, 2026 | James D Hoefelmeyer | nsf.gov |
| Development of Germanium Ring-Contact Detectors for LEGEND-1000 | NSF | Physics Section | 2023 | $343,667 | August 1, 2023 | July 31, 2027 | Dongming Mei | nsf.gov |
| Collaborative Research: Construction and Deployment of a Cryogenic, Undoped CsI Scintillator at the Spallation Neutron Source within the COHERENT Experiment | NSF | Physics Section | 2024 | $343,512 | September 1, 2024 | August 31, 2027 | Jing Liu | nsf.gov |
| Cultivating Career Pathways for Advanced Manufacturing Technicians | NSF | Workforce & Talent Continuum Section | 2023 | $342,504 | October 1, 2023 | September 30, 2027 | Brooks Jacobsen | nsf.gov |
| Collaborative Research: E-RISE RII: Germanium-based Science and Technology Advancement Research | NSF | Office of Integrative Activities | 2025 | $337,678 | July 1, 2025 | June 30, 2029 | Brianna Mount | nsf.gov |
| Dysfunction of the Cerebral Microcirculation by In Utero Exposure to Alcohol | NIH | National Institute on Alcohol Abuse and Alcoholism | 2021 | $330,750 | September 20, 2018 | August 31, 2024 | MAYHAN, WILLIAM G | reporter.nih.gov |
| Developing a blood fatty acid-based algorithm as an early predictor of insulin resistance: Applying machine learning to harmonized data from prospective cohort studies | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 | $327,420 | May 22, 2023 | May 21, 2025 | JACKSON, KRISTINA HARRIS | reporter.nih.gov |
| The Pediatric Biomedical Research Program | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2023 | $311,959 | January 10, 2019 | December 31, 2025 | LEE, LANCE | reporter.nih.gov |
| Collaborative Research: RUI: Topologically protected magnetic phases in Heusler alloys | NSF | Materials Research Section | 2025 | $310,230 | October 1, 2025 | September 30, 2028 | Parashu Kharel | nsf.gov |
| Engineering Human T Regulatory Cells with Chimeric Antigen Receptor Targeting NTPDase3 on the Surface of β cells for Type 1 Diabetes Control | NIH | National Institute of Allergy and Infectious Diseases | 2024 | $300,000 | September 6, 2024 | August 31, 2025 | SAVINOV, ALEXEI YURIEVITCH | reporter.nih.gov |
| EAGER: PBI: Collaboration Patterns and Socio-Economic Impacts Analysis in Emerging Science and Technology with Machine Learning Algorithms | NSF | Regional Innovation Section | 2024 | $300,000 | September 1, 2024 | August 31, 2027 | Kaiqun Fu | nsf.gov |
| POSE: Phase I: Open-Source Decision Support in the Design of Engineering Systems | NSF | TIP - Core Programs | 2025 | $300,000 | January 1, 2026 | December 31, 2027 | Lin Guo | nsf.gov |
| EAGER: SYNPLASOMES - SYNthetic PLAnt epiSOMES for plant genome editing and engineering | NSF | Innovation Tools, Informatics, & Functional Genomics | 2024 | $299,988 | August 1, 2024 | July 31, 2027 | Bernie Wone | nsf.gov |
| EPSCoR Research Fellows: NSF: Toward Simulating Few-Nucleon Interactions on Quantum Computers | NSF | Office of Integrative Activities | 2025 | $299,956 | February 1, 2026 | January 31, 2028 | Peng Guo | nsf.gov |
| RII Track-4: NSF: Bio-inspired Solutions to Prevent Soil Erosion in Farmland and Scouring in Fluvial Regions | NSF | Office of Integrative Activities | 2024 | $299,797 | February 1, 2024 | January 31, 2027 | Aritra Banerjee | nsf.gov |
| EPSCoR Research Fellows: NSF: Evolution of Planetary Interiors - Insights from Orthopyroxene/Melt Trace Element Partitioning Experiments | NSF | Office of Integrative Activities | 2026 | $292,174 | January 1, 2027 | December 31, 2028 | Gokce K Ustunisik | nsf.gov |
| Collaborative Research: How do accretionary sutures evolve into Cordilleran strike-slip faults? | NSF | GEO - Core Programs | 2024 | $291,843 | August 15, 2024 | July 31, 2027 | Trevor S Waldien | nsf.gov |
| CAREER: Deciphering Large-Scale Real Outage Data for Cascading Failure Analysis, Prevention, and Intervention | NSF | Electrical, Communications, & Cyber Systems | 2024 | $289,837 | October 1, 2023 | May 31, 2027 | Junjian Qi | nsf.gov |
| LUBAC-dependent regulation of cell death | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $280,102 | September 1, 2021 | February 28, 2023 | LOPEZ-MOSQUEDA, JAIME | reporter.nih.gov |
| Collaborative Research: E-CORE RII: South Dakota Research Ecosystem Network: Advancing STEM Education | NSF | Office of Integrative Activities | 2024 | $278,407 | May 15, 2024 | April 30, 2028 | Alessandra Higa | nsf.gov |
| SPURA - Summer Program for Undergraduate Research in Addiction | NIH | National Institute on Drug Abuse | 2021 to 2023 | $277,278 | June 15, 2013 | February 28, 2025 | BURRELL, BRIAN DONALD | reporter.nih.gov |
| Democratizing statistical computing through AI | NIH | National Institute of General Medical Sciences | 2024 | $273,987 | July 15, 2024 | July 14, 2025 | BURKHALTER, DANIEL | reporter.nih.gov |
| Collaborative Research: Design and mechanistic studies on microenvironment-sensitive polymeric nanoparticles for simultaneous contents release and ultrasound imaging | NSF | Materials Research Section | 2025 | $272,799 | June 1, 2025 | August 31, 2027 | Sanku Mallik | nsf.gov |
| Enhancing Vivarium Efficiency and Safety at South Dakota State University with a Modernized Pass-Through Autoclave | NIH | Office of the Director, National Institutes of Health | 2023 | $258,080 | July 1, 2023 | June 30, 2024 | MUCCIANTE, MICHELE RENE | reporter.nih.gov |
| EPSCoR Research Fellows: NSF: Machine Learning for Faster Simulation of Neutrino Detectors | NSF | Office of Integrative Activities | 2026 | $257,733 | January 1, 2027 | December 31, 2028 | Doojin Kim | nsf.gov |
| LEAPS-MPS: Topological Machine Learning and Cryo-EM | NSF | Mathematical Science Section | 2024 | $256,891 | September 1, 2024 | August 31, 2027 | Michael A Puthawala | nsf.gov |
| REU Site: Multidisciplinary Underground Science at the Sanford Underground Research Facility | NSF | Physics Section | 2025 | $252,269 | May 1, 2025 | April 30, 2028 | Brianna Mount | nsf.gov |
| REU Site: Multidisciplinary Underground Science at the Sanford Underground Research Facility | NSF | Division Of Physics | 2022 | $251,244 | May 1, 2022 | April 30, 2026 | Brianna Mount | nsf.gov |
| LEAPS-MPS: Toward Extracting the Scattering Phase Shift from Integrated Correlation Functions of Two-Nucleon Interaction in LQCD | NSF | Physics Section | 2024 | $250,000 | August 1, 2024 | July 31, 2027 | Peng Guo | nsf.gov |
| LEAPS-MPS: Water-soluble Afterglow Luminescent Nanocomposites for Bioimaging and Bioanalysis | NSF | Chemistry Section | 2023 | $249,128 | September 15, 2023 | August 31, 2026 | Steven X Wu | nsf.gov |
| CAREER: Understanding Structure-Function Relationships of Polyoxovanadate-Alkoxide Clusters from a Bottom-Up Perspective | NSF | Division Of Chemistry | 2022 | $247,711 | March 1, 2022 | October 31, 2024 | Pere Miro | nsf.gov |
| Collaborative Research: Mechanistic study of mesoporous carbon formation from food waste | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $245,000 | August 1, 2023 | July 31, 2027 | Rajesh V Shende | nsf.gov |
| Eco-Design of Hydrogenation Catalysts for Oxyanion Reduction: The Overlooked Roles of Nitrogen-Containing Groups on the Catalyst Supports | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2023 | $231,037 | January 1, 2024 | April 30, 2026 | Tao Ye | nsf.gov |
| RUI: Strong-Field Control of Intramolecular Dynamics in Polyatomic Molecules | NSF | Physics Section | 2026 | $230,573 | July 1, 2026 | June 30, 2029 | Eric Wells | nsf.gov |
| Collaborative Research: Transformation of Phenols to Aliphatic Disinfection Byproducts: Identifying Critical Factors and Strategies that Minimize Intermediate Halophenols | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $229,589 | January 1, 2025 | December 31, 2027 | Guanghui Hua | nsf.gov |
| Collaborative Research: E-RISE RII: Germanium-based Science and Technology Advancement Research | NSF | Office of Integrative Activities | 2025 | $218,423 | July 1, 2025 | June 30, 2029 | Robert J McTaggart | nsf.gov |
| RUI: Strong-Field Control of Intramolecular Dynamics in Polyatomic Molecules | NSF | Physics Section | 2023 | $216,613 | August 1, 2023 | July 31, 2027 | Eric Wells | nsf.gov |
| Transonic Flows in Multidimensional Conservation Laws | NSF | Mathematical Science Section | 2025 | $215,000 | September 1, 2025 | November 30, 2026 | Eun Heui Kim | nsf.gov |
| Collaborative Research: Advanced Oxidation Processes for the Control of Iodinated Disinfection Byproducts in Drinking Water | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $209,472 | September 1, 2023 | August 31, 2027 | Guanghui Hua | nsf.gov |
| CHAI: Improving the Resiliency and Security of the Cyber-Infrastructure at SWC | NSF | Div. of Equity for Excellence in STEM | 2022 | $208,258 | August 15, 2022 | July 31, 2023 | Scott Morgan | nsf.gov |
| Collaborative Research: The DarkSide Dark-Matter Search Using Liquid Argon | NSF | Physics Section | 2023 | $202,015 | September 1, 2023 | August 31, 2027 | Andrew K Alton | nsf.gov |
| ERI: Meniscus Tear Healing with Hydrophilic Polydopamine (hPDA) Fueled Hydrogel Bioadhesive | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $200,000 | September 1, 2024 | February 28, 2027 | Solaiman Tarafder | nsf.gov |
| ERI: Ultrasonic Guided Wave-based Battery Monitoring Algorithms and Remaining Useful Life Prediction | NSF | Electrical, Communications, & Cyber Systems | 2025 | $200,000 | July 1, 2025 | June 30, 2027 | Shabbir Ahmed | nsf.gov |
| ERI: Adaptive Multi-Fidelity Framework for Modeling Heterogeneous Materials Under Extreme Conditions | NSF | Civil, Mechanical, & Manufacturing Innovation | 2025 | $200,000 | June 15, 2025 | May 31, 2027 | Prashant K Jha | nsf.gov |
| ERI: A Portable Wideband Rydberg Atom-Based Quantum Antenna for HF/VHF Communications | NSF | Electrical, Communications, & Cyber Systems | 2026 | $200,000 | May 15, 2026 | April 30, 2028 | Kai Ren | nsf.gov |
| ERI: Understanding and Harnessing Exciton Polaritons for High-Performance 2D Heterostructure Optoelectronic Devices | NSF | Electrical, Communications, & Cyber Systems | 2026 | $200,000 | June 1, 2026 | May 31, 2028 | Mingyuan Chen | nsf.gov |
| ERI: Towards Engineered LiVIng metaSurfaces (ELVIS)- Understanding and Modeling Biofilm Growth on a Heterogeneous Surface for Environmentally Benign Biofouling Mitigation | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2026 | $199,994 | July 1, 2026 | June 30, 2028 | Joseph J Thalakkottor | nsf.gov |
| Research Initiation: Investigating the Connection Among Undergraduate Engineering Students Data Proficiency, Motivation, and Engineering Identity | NSF | Division of Engineering Education and Centers | 2022 | $199,286 | September 1, 2022 | November 30, 2022 | Kim-Doang Nguyen | nsf.gov |
| Conference: Workshop for Artificial Intelligence-powered Materials Discovery at Grant Plains | NSF | Office of Integrative Activities | 2024 | $199,280 | October 1, 2024 | September 30, 2026 | Dongming Mei | nsf.gov |
| ERI: Data-Driven Analysis and Dynamic Modeling of Residential Power Demand Behavior: Using Long-Term Real-World Data from Rural Electric Systems | NSF | Electrical, Communications, & Cyber Systems | 2023 | $198,740 | January 1, 2024 | December 31, 2026 | Long Zhao | nsf.gov |
| Development of a Clinically Relevant Genetically Engineered Mouse Model for Human High-Risk Rhabdomyosarcoma | NIH | National Cancer Institute | 2025 | $194,013 | December 11, 2024 | November 30, 2026 | TAO, JIANNING | reporter.nih.gov |
| ERI: Revealing the Reconfiguration Dynamics of Lipid Bilayer and Its Hydration Structures with Nanoscale Resolution during Electroporation | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $191,995 | June 1, 2023 | May 31, 2027 | SHAN ZHOU | nsf.gov |
| Equipment: MRI Track 1: Acquisition of NextGen-O2k all-in-one System for Multidisciplinary Research and Education at The University of South Dakota. | NSF | Infrastructure, Institutes, & Centers | 2024 | $186,930 | September 1, 2024 | August 31, 2027 | Omera B Matoo | nsf.gov |
| RUI: Studying the Strong Nuclear Force at Augustana University | NSF | Physics Section | 2023 | $183,219 | September 1, 2023 | August 31, 2027 | Nathan Grau | nsf.gov |
| RII Track-4: Research and Development of Ring-Contact Germanium Detectors | NSF | OIA-Office of Integrative Activities | 2022 | $182,744 | February 1, 2022 | May 31, 2023 | Wenzhao Wei | nsf.gov |
| Collaborative Research: REU Site: C3: Collaboration to Combat Crime - An Interdisciplinary Approach | NSF | Engineering Education Centers | 2024 | $177,162 | September 1, 2024 | August 31, 2027 | Rachel A Willand-Charnley | nsf.gov |
| RUI: Studying the Strong Nuclear Force at Augustana University | NSF | Physics Section | 2026 | $175,000 | August 15, 2026 | July 31, 2029 | Nathan Grau | nsf.gov |
| CRII: NeTS: Resource Management for Mobile Terminal Collaboration with Incomplete Information: From Theory to Practice | NSF | Software & Systems Foundations | 2024 | $174,892 | October 1, 2024 | September 30, 2026 | Jun Huang | nsf.gov |
| CAREER: Uncovering Mechanisms of DNA-protein Crosslink Repair | NSF | Division of Molecular and Cellular Biosciences | 2022 | $174,062 | May 1, 2022 | August 31, 2023 | Jaime Lopez-Mosqueda | nsf.gov |
| CAREER: Integrin-Mediated Mechanotransduction of Articular Chondrocytes | NSF | Division of Civil, Mechanical, and Manufacturing Innovation | 2022 | $172,252 | August 15, 2022 | November 30, 2024 | Scott Wood | nsf.gov |
| RII Track-4:NSF: Exploring the Potential of ANNIE Physics Phase and Beyond | NSF | OIA-Office of Integrative Activities | 2022 | $169,803 | February 1, 2022 | January 31, 2026 | Jingbo Wang | nsf.gov |
| Upgrade of geochemical analytical facilities at South Dakota Mines | NSF | Division Of Earth Sciences | 2022 | $158,475 | February 15, 2022 | January 31, 2024 | Sarah W Keenan | nsf.gov |
| CAREER: CAS-Climate: Sustainable Design Principles for Emerging Photovoltaics | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2023 | $158,158 | June 1, 2023 | November 30, 2023 | ilke celik | nsf.gov |
| Collaborative Research: REU Site: C3: Collaboration to Combat Crime - An Interdisciplinary Approach | NSF | Engineering Education Centers | 2024 | $156,680 | September 1, 2024 | August 31, 2027 | Randy C Hoover | nsf.gov |
| "SMART" nanoparticle delivery of veratridine overcomes clinical challenges in metastatic colorectal cancer. | NIH | National Cancer Institute | 2024 to 2025 | $149,500 | May 1, 2024 | October 31, 2026 | REZVANI, KHOSROW SAMUEL | reporter.nih.gov |
| Stress and Affective Mechanisms that Relate to Inflammation in Diverse Older Men and Women | NIH | National Institute on Aging | 2024 | $148,500 | September 15, 2024 | August 31, 2026 | WITZEL, DAKOTA DANIELLE | reporter.nih.gov |
| Collaborative Research: E-RISE RII: Germanium-based Science and Technology Advancement Research | NSF | Office of Integrative Activities | 2025 | $145,770 | July 1, 2025 | June 30, 2029 | Varghese M Vaidyan | nsf.gov |
| Documenting and archiving the Safe Passage Study in NICHD Data and Specimen Hub (DASH) | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2023 | $145,000 | September 8, 2022 | August 31, 2024 | HOCKETT, CHRISTINE W | reporter.nih.gov |
| MRI: Track 1 Acquisition of a Bench Top Powder X-ray Diffractometer Enabling Research, Education, and Outreach in the Upper Great Plains | NSF | Chemistry Section | 2025 | $142,977 | September 1, 2025 | August 31, 2028 | James D Hoefelmeyer | nsf.gov |
| Collaborative Research: E-CORE RII: South Dakota Research Ecosystem Network: Advancing STEM Education | NSF | Office of Integrative Activities | 2024 | $140,865 | May 15, 2024 | April 30, 2028 | Daniel Mourlam | nsf.gov |
| Probing the Dark Sector with AI/ML and Quantum Sensing | NSF | Physics Section | 2026 | $140,000 | August 15, 2026 | July 31, 2028 | Doojin Kim | nsf.gov |
| Collaborative Research: REU Site: C3: Collaboration to Combat Crime - An Interdisciplinary Approach | NSF | Engineering Education Centers | 2024 | $139,546 | September 1, 2024 | August 31, 2027 | Chaoyang Jiang | nsf.gov |
| Collaborative Research: Advanced and Highly Integrated Power Conversion Systems for Grid Stability and Resiliency | NSF | Division of Electrical, Communications and Cyber Systems | 2024 | $135,956 | October 1, 2023 | June 30, 2025 | Junjian Qi | nsf.gov |
| CAREER: A longitudinal study of the emotional and behavioral processes of Environmental Identity Development among rural and non-rural Alaskan children | NSF | Division of Behavioral and Cognitive Sciences | 2022 | $132,491 | October 1, 2021 | June 30, 2024 | Carie J Green | nsf.gov |
| Collaborative Research: Advanced Oxidation Processes for the Control of Iodinated Disinfection Byproducts in Drinking Water | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2023 | $114,421 | September 1, 2023 | December 31, 2025 | Tao Ye | nsf.gov |
| Collaborative Research: E-CORE RII: South Dakota Research Ecosystem Network: Advancing STEM Education | NSF | Office of Integrative Activities | 2024 | $110,846 | May 15, 2024 | April 30, 2028 | Sharon S Vestal | nsf.gov |
| RII Track-4:NSF: The Monitoring of Invasive Yellow Sweet Clover Using Landsat/Sentinel-2, UAV Imagery and Machine Learning | NSF | Office of Integrative Activities | 2023 | $100,607 | January 15, 2023 | December 31, 2026 | Ranjeet John | nsf.gov |
| Molecular Regulators of Renal Collecting Duct Differentiation and Maintenance | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 | $100,000 | July 1, 2016 | February 29, 2024 | SURENDRAN, KAMESWARAN | reporter.nih.gov |
| Planning: South Dakota NSF EPSCoR Track-1 Planning Grant | NSF | Office of Integrative Activities | 2023 | $100,000 | January 15, 2023 | August 31, 2024 | Kinchel C Doerner | nsf.gov |
| Conference: Creating Capacity and Connections to Expand Research Support Across the Northern Plains | NSF | OIA-Office of Integrative Activities | 2023 | $99,998 | August 1, 2023 | July 31, 2025 | Dianne L Nagy | nsf.gov |
| PFI-TT: Validation of a Modular Osteoarthritis Disease Model System for Early Stage Pharmaceutical Drug Screening | NSF | Translational Impacts | 2023 | $80,475 | September 1, 2023 | February 28, 2025 | Scott Wood | nsf.gov |
| Great Plains Rare Disease Summit | NIH | National Center for Advancing Translational Sciences | 2021 to 2024 | $75,001 | April 1, 2020 | March 31, 2026 | WEIMER, JILL M | reporter.nih.gov |
| Building Capacity to Address STEM Educator Shortages in Rural South Dakota | NSF | Division Of Undergraduate Education | 2023 | $74,992 | April 1, 2023 | March 31, 2025 | Bentley Sayler | nsf.gov |
| Tracing Intratumoral Cellular Heterogeneity using genetic barcoding in small cell lung cancer | NIH | National Cancer Institute | 2021 to 2022 | $68,043 | February 1, 2021 | August 19, 2022 | WOLLENZIEN, HANNAH G. | reporter.nih.gov |
| Metal-organic Framework Encapsulation of Biomolecules for Ultra-stable Diagnostic Assays and Sensors in Resource-limited Settings | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 | $65,786 | February 1, 2020 | August 22, 2022 | WANG, CONGZHOU | reporter.nih.gov |
| Collaborative Research: RAPID: Typhoon Merbok in coastal western Alaska: Extent of flooding and impacts on plant communities and ecosystem function | NSF | Office of Polar Programs (OPP) | 2023 | $63,362 | December 1, 2022 | November 30, 2024 | A Joshua Leffler | nsf.gov |
| Collaborative Research: E-CORE RII: South Dakota Research Ecosystem Network: Advancing STEM Education | NSF | Office of Integrative Activities | 2024 | $57,601 | May 15, 2024 | April 30, 2028 | Betsy Schamber | nsf.gov |
| RII Track-4 NSF: Novel Structure and Properties of Hybrid Electrolytes for Lithium Metal Batteries | NSF | Office of Integrative Activities | 2022 | $55,910 | February 1, 2022 | May 31, 2023 | Yue Zhou | nsf.gov |
| Graduate Research Fellowship Program (GRFP) | NSF | Scholarships, Fellowships, and Traineeships Section | 2026 | $53,000 | August 15, 2026 | July 31, 2031 | Maribeth H Price | nsf.gov |
| Graduate Research Fellowship Program (GRFP) | NSF | Scholarships, Fellowships, and Traineeships Section | 2026 | $53,000 | August 15, 2026 | July 31, 2031 | Katherine E Wenzell | nsf.gov |
| The role of proBDNF-p75NTR signaling in hind limb ischemia. | NIH | National Heart, Lung, and Blood Institute | 2023 to 2024 | $52,632 | February 1, 2023 | May 31, 2024 | ABY, KATHERINE | reporter.nih.gov |
| Dynamic Regulation of Vesicular Trafficking by Altered Sterol Homeostasis | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $51,036 | February 20, 2018 | February 19, 2022 | ANDERSON, RUTHELLEN HOPE | reporter.nih.gov |
| I-Corps: Activated carbon pad to deliver glucosinolates and myrosinase enzymes to extend the shelf-life of strawberries | NSF | Translational Impacts | 2022 | $50,000 | April 1, 2022 | September 30, 2023 | Zhengrong Gu | nsf.gov |
| I-Corps: Wastewater Treatment Using Anaerobic Membranes Bioreactor with Electrolyte Regeneration | NSF | Translational Impacts | 2022 | $50,000 | April 15, 2022 | March 31, 2024 | Travis W Walker | nsf.gov |
| I-Corps: Dentifrices With Targeted Drug Release | NSF | Translational Impacts | 2024 | $50,000 | December 1, 2023 | November 30, 2024 | Grigoriy Sereda | nsf.gov |
| I-Corps: Translation Potential of a Remote Sensing-Based Measurement, Reporting, and Verification Tool for Sustainable Agriculture | NSF | Pathways for Translation Section | 2024 | $50,000 | May 15, 2024 | December 31, 2026 | Ranjeet John | nsf.gov |
| I-Corps: Translation Potential of a Tailored Drug Delivery Device for Peripheral Artery Disease | NSF | Pathways for Translation Section | 2025 | $50,000 | December 1, 2024 | November 30, 2026 | Daniel Engebretson | nsf.gov |
| I-Corps: Translation potential of a helmet designed to offer protection for individuals engaging in head-directed self-injurious behaviors | NSF | Pathways for Translation Section | 2026 | $50,000 | August 1, 2026 | July 31, 2027 | Lacy Knutson | nsf.gov |
| Collaborative Research: E-CORE RII: South Dakota Research Ecosystem Network: Advancing STEM Education | NSF | Office of Integrative Activities | 2024 | $49,353 | May 15, 2024 | April 30, 2028 | Jon C Mitchell | nsf.gov |
| ERI: Advancing understanding of data-driven wildfire evacuation planning for communities with transient populations in the wildland-urban interface | NSF | Division of Civil, Mechanical, and Manufacturing Innovation | 2022 | $44,040 | March 1, 2022 | November 30, 2023 | Dapeng Li | nsf.gov |
| Developmental Research Program for Medical Students (DRPMS) | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 | $36,508 | August 17, 2017 | July 31, 2022 | MANZERRA, PASQUALE | reporter.nih.gov |
| Conference: The Midwest Optimization Meeting 2026 | NSF | Mathematical Science Section | 2026 | $33,495 | September 1, 2026 | August 31, 2027 | Thi Dai Trang Nguyen | nsf.gov |
| Collaborative Research: Transformation of Phenols to Aliphatic Disinfection Byproducts: Identifying Critical Factors and Strategies that Minimize Intermediate Halophenols | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2024 | $25,393 | January 1, 2025 | December 31, 2025 | Tao Ye | nsf.gov |
| Collaborative Research: E-CORE RII: South Dakota Research Ecosystem Network: Advancing STEM Education | NSF | Office of Integrative Activities | 2024 | $20,165 | May 15, 2024 | April 30, 2028 | Randy C Hoover | nsf.gov |
| Collaborative Research: E-CORE RII: South Dakota Research Ecosystem Network: Advancing STEM Education | NSF | Office of Integrative Activities | 2024 | $19,624 | May 15, 2024 | April 30, 2028 | Sally Mallowa | nsf.gov |
| ERI: CAS- Climate: Design for Recyclability: Perovskite Solar Technology for Sustainable Energy Future | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2022 | $16,748 | February 15, 2022 | November 30, 2023 | ilke celik | nsf.gov |
| Conference: 2024 Conference on Science at Sanford Underground Research Facility | NSF | Division Of Physics | 2024 | $10,000 | May 15, 2024 | October 31, 2024 | Jingbo Wang | nsf.gov |
| Graph Theoretical Methods for Blockchain Data Analysis | NSF | Division Of Mathematical Sciences | 2022 | $7,562 | July 1, 2022 | December 31, 2022 | Christopher Saunders | nsf.gov |
| Conference: SDSU Data Science Symposium | NSF | Division Of Mathematical Sciences | 2025 | $7,502 | February 15, 2025 | July 31, 2025 | Frederick J Boehm | nsf.gov |
| Conference: SDSU Data Science Symposium | NSF | Division Of Mathematical Sciences | 2024 | $7,500 | February 1, 2024 | July 31, 2024 | Semhar Michael | nsf.gov |
| CRII: III: Learning Spatiotemporal Impacts of Text-enriched Traffic Events with Injection of Interpretability from Graph Neural Networks and Physics-Informed Machine Learning | NSF | Division of Information & Intelligent Systems | 2024 | $5,822 | August 1, 2024 | October 31, 2025 | Kaiqun Fu | nsf.gov |
| Evolution of Salmonella in a cockroach vector | NIH | National Institute of Allergy and Infectious Diseases | 2024 | $1 | July 5, 2024 | September 17, 2024 | PIETRI, JOSE ENRIQUE | reporter.nih.gov |
Organizations by funding
| Organization | Place | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|---|
| University of South Dakota Main Campus | Vermillion, SD | 24 | $39.4 million | 30 | $13 million |
| South Dakota State University | Brookings, SD | 11 | $14.3 million | 52 | $27.5 million |
| Sanford Research/usd | Sioux Falls, SD | 24 | $34.5 million | 1 | $378,652 |
| Avera Mckennan | Sioux Falls, SD | 6 | $34.3 million | 0 | $0 |
| South Dakota School of Mines and Technology | Rapid City, SD | 0 | $0 | 56 | $33.6 million |
| Black Hills State University | Spearfish, SD | 2 | $867,213 | 7 | $9.7 million |
| Missouri Breaks Research, Inc. | Eagle Butte, SD | 2 | $7.6 million | 0 | $0 |
| Oglala Lakota College | Kyle, SD | 0 | $0 | 4 | $5.6 million |
| Dakota State University | Madison, SD | 0 | $0 | 6 | $5.3 million |
| Sisseton Wahpeton Community College | Agency Village, SD | 0 | $0 | 3 | $5.2 million |
| Black Hills Ctr/american Indian Health | Rapid City, SD | 1 | $4.1 million | 0 | $0 |
| Mount Marty College | Yankton, SD | 0 | $0 | 2 | $3 million |
| Augustana University Association | Sioux Falls, SD | 0 | $0 | 7 | $2.2 million |
| South Dakota Board of Regents | Pierre, SD | 0 | $0 | 2 | $1.1 million |
| Omegaquant Analytics, LLC | Sioux Falls, SD | 2 | $833,920 | 0 | $0 |
| Rtutor, LLC | Brookings, SD | 2 | $669,303 | 0 | $0 |
| South Dakota School of Mines and Techn'y | Rapid City, SD | 2 | $479,265 | 0 | $0 |
| Enrectec LLC | Sioux Falls, SD | 1 | $475,014 | 0 | $0 |
| Fatty Acid Research Institute | Sioux Falls, SD | 1 | $412,245 | 0 | $0 |
| Lake Area Technical College | Watertown, SD | 0 | $0 | 1 | $342,504 |
| Northern State University | Aberdeen, SD | 0 | $0 | 1 | $49,353 |
Funding by fiscal year
| Fiscal year | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|
| 2026 | 0 | $0 | 38 | $15,560,175 |
| 2025 | 34 | $28,843,305 | 48 | $34,097,440 |
| 2024 | 36 | $28,564,624 | 52 | $23,701,888 |
| 2023 | 42 | $30,519,012 | 40 | $15,769,930 |
| 2022 | 38 | $29,187,472 | 31 | $15,307,516 |
| 2021 | 31 | $20,792,870 | 0 | $0 |
Open federal funding opportunities
From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.
| Open opportunity | Number | Agency | Listing | Closes | Award ceiling | Why it matches |
|---|---|---|---|---|---|---|
| Unlocking Dataset Value for AI-Enabled Scientific Discovery (AI Datasets) | 26-512 | NSF | 47.041 | November 4, 2026 | Not listed | Same assistance listing 47.041 as 41 awards here |
| PFE: Research Initiation in Engineering Formation (PFE: RIEF) | 20-558 | NSF | 47.041 | November 10, 2026 | Not listed | Same assistance listing 47.041 as 41 awards here |
| National Science Foundation Translation to Practice (NSF TTP) | 25-540 | NSF | 47.041 | November 17, 2026 | $2 million | Same assistance listing 47.041 as 41 awards here |
| Training-based Workforce Development for Advanced Cyberinfrastructure | 23-520 | NSF | 47.041 | January 21, 2027 | $1 million | Same assistance listing 47.041 as 41 awards here |
| EPSCoR Research Infrastructure Improvement Program: Focused EPSCoR Collaborations (FEC) | 24-573 | NSF | 47.041 | January 26, 2027 | $1.5 million | Same assistance listing 47.041 as 41 awards here |
| GROWING CONVERGENCE RESEARCH (GCR) | 24-527 | NSF | 47.041 | February 8, 2027 | $3.6 million | Same assistance listing 47.041 as 41 awards here |
| Mid-scale Research Infrastructure-1 | 24-598 | NSF | 47.041 | February 8, 2027 | $20 million | Same assistance listing 47.041 as 41 awards here |
| EMERGING FRONTIERS IN RESEARCH AND INNOVATION (EFRI-2026/27): Wave-Based Computing ( EFRI-WBC) | 26-524 | NSF | 47.041 | February 11, 2027 | Not listed | Same assistance listing 47.041 as 41 awards here |
| Pathways to Enable Secure Open-Source Ecosystems (PESOSE) | 26-506 | NSF | 47.041 | March 2, 2027 | Not listed | Same assistance listing 47.041 as 41 awards here |
| NSF National Quantum Virtual Laboratory (NQVL) | 24-586 | NSF | 47.041 | April 6, 2027 | Not listed | Same assistance listing 47.041 as 41 awards here |
| EPSCoR Research Infrastructure Improvement (RII): EPSCoR Research Fellows | 24-528 | NSF | 47.041 | April 13, 2027 | Not listed | Same assistance listing 47.041 as 41 awards here |
| IUSE / Professional Formation of Engineers: Revolutionizing Engineering Departments (IUSE/PFE: RED) | 24-564 | NSF | 47.041 | April 13, 2027 | $2 million | Same assistance listing 47.041 as 41 awards here |
| Findable Accessible Interoperable Reusable Open Science (FAIROS) | 25-533 | NSF | 47.041 | April 14, 2027 | Not listed | Same assistance listing 47.041 as 41 awards here |
| EPSCoR Graduate Fellowship Program (EGFP) | 24-588 | NSF | 47.041 | June 1, 2027 | $3.2 million | Same assistance listing 47.041 as 41 awards here |
| Faculty Early Career Development Program (CAREER) | 22-586 | NSF | 47.041 | July 28, 2027 | Not listed | Same assistance listing 47.041 as 41 awards here |
| Research Experiences for Undergraduates (REU) | 23-601 | NSF | 47.041 | August 18, 2027 | $500,000 | Same assistance listing 47.041 as 41 awards here |
| Engineering Research Initiation (ERI) | 24-590 | NSF | 47.041 | September 16, 2027 | Not listed | Same assistance listing 47.041 as 41 awards here |
| Research Experiences for Teachers (RET) in Engineering and Computer Science | 24-503 | NSF | 47.041 | October 13, 2027 | Not listed | Same assistance listing 47.041 as 41 awards here |
| Historically Black Colleges and Universities - Excellence in Research (HBCU - EiR) | 23-598 | NSF | 47.041 | October 19, 2027 | Not listed | Same assistance listing 47.041 as 41 awards here |
| Transport Phenomena (TP) | PD-26-366Y | NSF | 47.041 | August 20, 2076 | Not listed | Same assistance listing 47.041 as 41 awards here |
Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.