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Data / Research funding / Chemistry of Life Processes

NSF program Chemistry of Life Processes (688300): 209 awards, $114.9M to 125 organizations

209 NSF awards ($114.9M) under the program element Chemistry of Life Processes (688300) to 125 organizations, fiscal years 2022 to 2026, read 2026-11-03.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Program element code
688300
Directorate
Directorate for Mathematical and Physical Sciences
Division
Chemistry Section

Awards

209 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
MFB: Evaluating and Advancing Cryo-EM for RNA Conformational EnsemblesNSFChemistry Section2024$1,500,000March 1, 2024February 28, 2027Rhiju Dasnsf.gov
Defining Barriers to Nucleosome Mobility through Single-Molecule ManipulationNSFMolecular Biosciences2025$1,399,593September 1, 2025August 31, 2029Gregory D Bowmannsf.gov
DNA glycosylases involved in interstrand crosslink repair and antibiotic self-resistanceNSFMolecular Biosciences2024$1,300,000April 1, 2024March 31, 2028Brandt F Eichmannsf.gov
PPM: Illuminating the Dihydrouridine EpitranscriptomeNSFMolecular Biosciences2025$1,150,000February 15, 2025January 31, 2028Ralph E Kleinernsf.gov
Development of Natural Product-Inspired Ubiquinone Mimics as Next Generation AgrochemicalsNSFChemistry Section2023$1,067,220September 15, 2023August 31, 2028William M Wuestnsf.gov
CAREER: A Novel Twist in Nature; Proteins with a Pierced Lasso TopologyNSFChemistry Section2022$970,600February 1, 2022January 31, 2029Ellinor B Haglundnsf.gov
Specialized Nucleotide Metabolism and its Molecular Role in Modulating Microbial Community DynamicsNSFChemistry Section2025$960,000April 15, 2025March 31, 2028Jason M Crawfordnsf.gov
The hidden side of selenoprotein S: its binding and reaction partners beyond protein degradationNSFMolecular Biosciences2022$952,813September 1, 2022August 31, 2027Sharon Rozovskynsf.gov
Collaborative Research: De Novo Protein Constructs for Photosynthetic Energy TransductionNSFChemistry Section2025$924,000September 1, 2025August 31, 2028Michael J Theriennsf.gov
How Nature Repurposes Protein Folds to Catalyze Pericyclic Reactions, and New Computational Methods to Understand Pericyclase MechanismsNSFChemistry Section2024$900,000September 1, 2024August 31, 2027Kendall N Houknsf.gov
Nonenzymatic RNA ReplicationNSFChemistry Section2023$899,998April 1, 2023September 30, 2027Jack W Szostaknsf.gov
Role of Coupled Amino Acids in the Mechanisms of Enzyme CatalysisNSFMolecular Biosciences2022$869,536July 1, 2022June 30, 2026Mary Jo Ondrechennsf.gov
CAREER: Elucidating the Chemistry of Biological Lanthanide Chelators for Rare Earth Element SeparationNSFChemistry Section2025$850,000July 15, 2025June 30, 2030Allegra T Aronnsf.gov
New Approaches to Catalyst Screening and DevelopmentNSFChemical, Bioengineering, Environmental, & Transport Systems2024$847,296August 1, 2024July 31, 2027David S Hagensf.gov
CAREER: Illuminating O-GlcNAc-Driven Functions of the Human ProteomeNSFChemistry Section2023$833,727July 15, 2023June 30, 2028Charlie Fehlnsf.gov
PPM - How Is Protein Arginine Methylation Coordinated with Other Modifications to Effect Biological FunctionNSFChemistry Section2026$830,581February 1, 2026January 31, 2029Steven G Clarkensf.gov
CAREER: Computationally Illuminating the Molecular Interplay between N-glycosylation and Ion Channel GatingNSFChemistry Section2025$827,000April 15, 2025March 31, 2030Jing Linsf.gov
CAREER: The Lassa Virus Fusion Domain - A Cyclic Approach to Revealing the Molecular Chemistry behind Membrane FusionNSFChemistry Section2023$820,000April 1, 2023March 31, 2028Jin Woo Leensf.gov
CAREER: Breaking Down the Structure-function Relationships in Enzymes that Catabolize ChlorophyllNSFChemistry Section2024$820,000April 1, 2024March 31, 2029Jennifer Bridwell-Rabbnsf.gov
CAREER: Interrogating Kinetic Mechanisms of Targeted Protein Degradation at ScaleNSFChemistry Section2024$820,000July 1, 2024June 30, 2029Fleur M Fergusonnsf.gov
CAREER: Biochemical and Structural Mechanisms Controlling tRNA-Modifying MetalloenzymesNSFChemistry Section2024$820,000March 1, 2024February 28, 2029Jeffrey S Mugridgensf.gov
CAREER: Rare Sugar Activation and Incorporation into Bacterial Glycan PolymersNSFChemistry Section2022$815,103August 1, 2022July 31, 2027Tania J Lupolinsf.gov
CAREER: Elucidating the Roles of Extracellular Metal Ions in Gut Microbiota InteractionsNSFChemistry Section2023$813,751February 1, 2023January 31, 2028Melissa L Zastrownsf.gov
CAREER: Chemical Tools for Bio-Orthogonal NeuromodulationNSFChemistry Section2023$803,672July 1, 2023June 30, 2028Timothy M Korternsf.gov
CAREER: Understanding and Exploiting Sequence Recognition by Cell Signaling ProteinsNSFChemistry Section2025$801,590April 1, 2025March 31, 2030Neel H Shahnsf.gov
Mapping the Collagenome with Stapled Collagen-Mimetic PeptidesNSFChemistry Section2025$800,000September 1, 2025August 31, 2028Joshua Kritzernsf.gov
CAREER: The Mechanistic Roles of Receptor Oligomerization in Molecular SignalingNSFChemistry Section2025$799,246May 1, 2025April 30, 2030Colin D Kinz-Thompsonnsf.gov
Roles of Heme and Protein Conformation in Ligand Binding Cooperativity and Selectivity in Bacterial Globin Coupled SensorsNSFChemistry Section2023$798,000August 1, 2023July 31, 2026Emily E Weinertnsf.gov
CAREER: Building and controlling the reactivity of a cobalt-porphyrin cofactorNSFChemical, Bioengineering, Environmental, & Transport Systems2023$794,889March 1, 2023July 1, 2026Andrew R Bullernsf.gov
CAREER: Understanding O2 activation by Manganese/Iron Oxygenases and their ModelsNSFChemistry Section2025$780,000August 1, 2025July 31, 2030Jonathan Rittlensf.gov
ATP Analogs to Study Human Histidine KinasesNSFChemistry Section2025$778,507September 1, 2025August 31, 2028Mary Kay H Pflumnsf.gov
CAREER: A Multidisciplinary Approach for the Discovery and Characterization of Hormone Inducers of Natural Product Biosynthetic Gene ClustersNSFChemistry Section2023$759,423February 1, 2023January 31, 2028Elizabeth I Parkinsonnsf.gov
CAREER: Molecular Evolution of Oxidant Specificity in Bacterial Flavoprotein Amine OxidasesNSFChemistry Section2023$757,000July 1, 2023June 30, 2028Frederick Stullnsf.gov
CAREER: Enzymatic Sulfur Incorporation and Modification in the Biosynthesis of Natural ProductsNSFDivision Of Chemistry2023$750,471February 1, 2023March 31, 2026JIE LInsf.gov
CAREER: Carbon Monoxide Sensing, Selectivity, and Signaling in MicrobesNSFChemistry Section2026$749,702April 1, 2026March 31, 2031Matthew R Dentnsf.gov
Biophysical Studies of Bifunctional Peptidylglycine alpha-Amidating Monooxygenase.NSFChemistry Section2025$724,746September 1, 2025August 31, 2028David J Merklernsf.gov
Structure and Function of Animal Polyketide Synthases: Bridging Lipid and Polyketide BiologyNSFDivision Of Chemistry2022$722,998July 1, 2022June 30, 2025Eric W Schmidtnsf.gov
Catalytic halogen bonds in enzymatic bond breaking and making in DNANSFChemistry Section2022$720,779September 1, 2022August 31, 2027Pui S Honsf.gov
Mechanisms of Protein Protection by Desiccation-tolerance MoleculesNSFChemistry Section2022$719,000September 1, 2022August 31, 2027Gary J Pielaknsf.gov
Biophysical Studies of MetalloenzymesNSFChemistry Section2024$705,000April 1, 2024March 31, 2028Brian M Hoffmannsf.gov
CAREER: Advancing Proximity Labeling Mass Spectrometry to Characterize Neuronal Mitochondrial DynamicsNSFChemistry Section2025$703,319September 1, 2025June 30, 2028Ling Haonsf.gov
CAREER: Chemical Probes to Interrogate Real-Time Cellular Activity of Lysine-based Post-translational Modification ErasersNSFChemistry Section2022$700,000December 15, 2021November 30, 2026Rongsheng Wangnsf.gov
CAREER: Peptidic Natural Products in Research and EducationNSFChemistry Section2023$700,000August 1, 2023July 31, 2028Vinayak Agarwalnsf.gov
CAREER: Discovering and Engineering Protein-Based Sensors for Nitrate in BiologyNSFChemistry Section2023$700,000September 1, 2023August 31, 2028Sheel C Dodaninsf.gov
CAREER: Bacterial Cytochrome P450 Enzymes and their Redox PartnersNSFChemistry Section2025$700,000May 1, 2025April 30, 2030Jeffrey D Rudolfnsf.gov
CAREER: New Reporters for Temporally-Gated Integration of Neuronal ActivityNSFChemistry Section2023$698,869September 15, 2023August 31, 2028Wenjing Wangnsf.gov
CAREER: Unraveling Diverse Mechanisms of Heme Degradation ProcessesNSFChemistry Section2022$695,000July 1, 2022June 30, 2027Piotr Maknsf.gov
CAREER: Computational Design of Fluorescent Proteins with Multiscale Excited State QM/MM MethodsNSFChemistry Section2024$690,816April 1, 2024March 31, 2029Alice R Walkernsf.gov
Development of cryogenic electron microscopy for probing phase separation in lipid membranesNSFChemistry Section2022$684,211July 1, 2022June 30, 2026Frederick A Heberlensf.gov
CAREER: Spectroscopic Studies of Functionally Significant Interactions in Iron-dependent Proteins and EnzymesNSFChemistry Section2022$670,000July 15, 2022June 30, 2027Katlyn K Meiernsf.gov
CAREER: Directly Visualizing the Conformational Dynamics and Non-covalent Interactions of Biological Macromolecules in Living Cells using Fast Raman Relaxation ImagingNSFChemistry Section2025$665,769May 1, 2025April 30, 2030David Punihaolensf.gov
DNA Strand Separation: A New Mechanism of DNA RecognitionNSFChemistry Section2024$663,956May 15, 2024April 30, 2027Norbert O Reichnsf.gov
CAREER: The Human Gut as an Untapped Reservoir for Bacteria and Enzymes that Degrade Lignin, a Potential Sustainable Source for Critical ChemicalsNSFChemistry Section2024$663,610April 1, 2024March 31, 2029Elizabeth N Bessnsf.gov
Evolutionarily Conserved Variations in Menaquinone Structure: Functional ImplicationsNSFChemistry Section2022$661,352September 1, 2022August 31, 2026Debbie C Cransnsf.gov
CAREER: Nucleic Acid-Catalyzed HalogenationsNSFChemistry Section2024$660,000July 1, 2024June 30, 2029Aaron E Engelhartnsf.gov
CAREER: Decoding Iron-Catalyzed Oxidation Mechanisms in Biology via Time-Resolved X-ray ApproachesNSFChemistry Section2026$658,531August 15, 2026July 31, 2031Katherine M Davisnsf.gov
Chemical Measurements and Imaging Using Novel Functional Nucleic AcidsNSFChemistry Section2024$658,000September 1, 2024August 31, 2027Hsin-Chih Yehnsf.gov
CAREER: Mechanistic Investigations of Conformational Activation and Catalysis in Emerging CRISPR-Cas SystemsNSFChemistry Section2022$650,111September 1, 2022August 31, 2027Giulia Palermonsf.gov
Structure and Divergent Mechanisms of Heme oxygenase-like dimetal oxidases/oxygenasesNSFChemistry Section2025$645,000September 1, 2025August 31, 2028Thomas M Makrisnsf.gov
CAREER: Understanding the Biosynthesis of Terpenoid MycotoxinsNSFChemistry Section2026$640,000August 15, 2026July 31, 2031Yang Hainsf.gov
Phospholipase D Regulation of Exosome SecretionNSFChemistry Section2023$639,461September 15, 2023August 31, 2027Michelle Knowlesnsf.gov
Chemical Toolkit for Monitoring and Modulating Receptor Tyrosine Phosphatase ActivityNSFChemistry Section2025$639,000September 1, 2025August 31, 2028Amy M Barriosnsf.gov
Exploring the Biosynthetic Landscape and Reaction Mechanisms of Non-Canonical Cytochrome P450 EnzymesNSFChemistry Section2026$630,000August 15, 2026July 31, 2029Mohammad R Seyedsayamdostnsf.gov
CAREER: New Chemical Tools for Probing the Biological Significance of Hydrogen Sulfide and Hydrogen SelenideNSFChemistry Section2022$625,000January 15, 2022December 31, 2026John C Lukeshnsf.gov
CAREER: Imaging the Chemical Nature of Intracellular Phase Separation by Functional Stimulated Raman Scattering Spectro-microscopyNSFChemistry Section2023$625,000April 1, 2023March 31, 2028Lu Weinsf.gov
Expanding the Bio(in)organic Chemistry of Reactive Sulfur and Selenium SpeciesNSFChemistry Section2026$622,797August 15, 2026July 31, 2029Michael D Pluthnsf.gov
Chemoreception: Linking Sequence, Structure, Mechanism, and InhibitionNSFChemistry Section2024$622,000June 1, 2024May 31, 2027Smita Mohantynsf.gov
Mechanistic Studies of C-X Bond Formation ChemistriesNSFChemistry Section2024$614,728August 1, 2024July 31, 2027Pinghua Liunsf.gov
Bifurcation in Context: Essential ingredients and coupling with partnersNSFChemistry Section2025$605,000January 1, 2026December 31, 2028Anne-Frances Millernsf.gov
Exploring Routes to Homochirality in the Synthesis of Biological PolymersNSFChemistry Section2025$602,976September 1, 2025August 31, 2028Donna G Blackmondnsf.gov
MFB: Probing Collective Ribosome Organization with PolySnap-seqNSFChemistry Section2025$600,000September 1, 2025August 31, 2028Oded Regevnsf.gov
Chemical & Biological Interception of Cell-Cell Communication in Gram-Positive BacteriaNSFChemistry Section2025$600,000September 1, 2025August 31, 2028Helen E Blackwellnsf.gov
Unraveling the Principles of Catalytic diversity in the Carotenoid Oxygenase SuperfamilyNSFChemistry Section2026$600,000August 15, 2026July 31, 2029Philip D Kisernsf.gov
Transition from Soluble to Insoluble Glucose Storage Polymers in Biological SystemsNSFChemistry Section2026$599,760September 1, 2026August 31, 2029Alan Myersnsf.gov
CAREER: Enzymatic Sulfur Incorporation and Modification in the Biosynthesis of Natural ProductsNSFChemistry Section2026$598,188February 15, 2026January 31, 2028JIE LInsf.gov
Structure and Function of Cyclodipeptide Oxidase-Like Enzyme FilamentsNSFChemistry Section2024$597,945May 1, 2024April 30, 2027Tobias W Giessennsf.gov
Modulating Copper Enzymatic Activity by Tuning Secondary Coordination Sphere InteractionsNSFChemistry Section2024$594,870August 1, 2024July 31, 2027Yi Lunsf.gov
Collaborative Research: Ethylene-Forming EnzymeNSFChemistry Section2022$593,759September 1, 2022August 31, 2027Robert P Hausingernsf.gov
Diazeniumdiolate Siderophores: Biosynthesis and ReactivityNSFChemistry Section2026$587,894November 1, 2026October 31, 2029Alison Butlernsf.gov
DNA-Protein Cross-link Formation by Chimeric Bis-electrophilesNSFChemistry Section2024$585,427May 1, 2024April 30, 2027Marc M Greenbergnsf.gov
Characterizing CmodAA-Containing Biosynthetic Pathways of Nonribosomal PeptidesNSFChemistry Section2023$577,690July 1, 2023June 30, 2027Bo Linsf.gov
Investigating Membrane Proteins with Magnetic Resonance SpectroscopyNSFChemistry Section2023$577,656September 15, 2023August 31, 2027Gary A Lorigannsf.gov
Chiral Amine Synthesis Using Engineered Pyridoxal-Dependent EnzymesNSFChemistry Section2026$576,000August 15, 2026July 31, 2029Todd K Hysternsf.gov
NSF-BSF: Unraveling Interspecies Communication between Microbes that Colonize HumansNSFChemistry Section2025$575,037September 1, 2025August 31, 2028Yftah Tal-Gannsf.gov
Chemical Affinity Probes for Discovery of Histidine MethylomeNSFChemistry Section2024$574,915July 1, 2024June 30, 2027Monika Rajnsf.gov
Collaborative Research: Exploring the Mechanisms, Functional Diversity, and Conformational Dynamics of Flavin-dependent MonooxygenasesNSFChemistry Section2025$572,018January 1, 2025December 31, 2027Pablo Sobradonsf.gov
CAREER: Diazaborine-Based Tools and Platforms for Mapping Intra- and Extracellular PeroxynitriteNSFChemistry Section2023$571,201April 1, 2023March 31, 2028Dylan W Domaillensf.gov
The Chemistry of Dihydropyrimidine DehydrogenaseNSFChemistry Section2022$567,000August 1, 2022July 31, 2027Graham R Morannsf.gov
Role of protein unfolding in endosomal escapeNSFDivision Of Chemistry2022$567,000August 1, 2022July 31, 2025Alanna Schepartznsf.gov
Menaquinone Biosynthesis via the Futalosine PathwayNSFChemistry Section2022$566,966September 1, 2022August 31, 2026Tadhg P Begleynsf.gov
Modulation of Metalloprotein Activities through Fine-tuning Reduction PotentialsNSFDivision Of Chemistry2022$561,000November 15, 2021September 30, 2024Yi Lunsf.gov
Imaging exocytosis via a combined fluorescence and amperometry approachNSFChemistry Section2022$560,163August 1, 2022July 31, 2026Timothy E Glassnsf.gov
Quantifying and Designing for Electrostatic Preorganization in EnzymesNSFDivision Of Chemistry2022$555,000September 1, 2022August 31, 2025Anastassia N Alexandrovansf.gov
Bacterial Reaction Centers with New Photochemical PropertiesNSFChemistry Section2024$555,000September 1, 2024August 31, 2027James P Allennsf.gov
Enzymatic Hydrolytic Dehalogenation of Chlorinated Aromatic CompoundsNSFChemistry Section2025$555,000September 1, 2025August 31, 2028Richard C Holznsf.gov
Elucidating the Interplay between the ComRS and the ComABCDE Quorum Sensing Circuitries in StreptococciNSFChemistry Section2023$552,000August 1, 2023July 31, 2027Yftah Tal-Gannsf.gov
Harnessing Large Protein Dynamics to Control Chemical TransformationsNSFChemistry Section2026$552,000August 15, 2026July 31, 2029Markos Koutmosnsf.gov
Expedient Synthesis of Glycosaminoglycan Saccharides with Defined Sulfation Patterns for Probing Human Protein Interactions.NSFChemistry Section2026$552,000September 1, 2026August 31, 2029Chi-Huey Wongnsf.gov
Time Resolved Studies of Fundamental Mechanisms in Natural PhotosynthesisNSFChemistry Section2023$550,879September 15, 2023August 31, 2026Yulia Pushkarnsf.gov
Tailoring Azirine Reactivity for Biological ApplicationsNSFChemistry Section2026$548,997August 15, 2026July 31, 2029Jianmin Gaonsf.gov
NSF/BIO-DFG: Biological Fe-S intermediates in the synthesis of nitrogenase metalloclustersNSFMolecular Biosciences2024$548,196February 1, 2024January 31, 2027Patricia C Dos Santosnsf.gov
Glycocalyx Engineering to Probe Mucin Signal TransductionNSFChemistry Section2024$543,251September 1, 2024August 31, 2027Jessica Kramernsf.gov
Mechanism and inhibition of organic and enzymatic isomerizationsNSFChemistry Section2023$543,183October 1, 2023September 30, 2027Andrew S Murkinnsf.gov
Mechanism and Scope of Prenylated-flavin-dependent (De)carboxylase EnzymesNSFDivision Of Chemistry2022$540,405December 15, 2022November 30, 2025E Neil G Marshnsf.gov
Unraveling the mechanistic roles of protein conformational transitions and water dynamics in ligand bindingNSFChemistry Section2025$540,000September 1, 2025August 31, 2028Ao Mansf.gov
The Mechanism of NO Reductases: N-N Bond Formation and Hyponitrite IntermediatesNSFChemistry Section2026$540,000September 1, 2026August 31, 2029Nicolai Lehnertnsf.gov
Biomimetic Reactivity and Spectroscopy of Trinuclear Copper Centers in Multicopper OxidasesNSFChemistry Section2025$539,215September 1, 2025August 31, 2028Shiyu Zhangnsf.gov
Development of Activity-Based Probes for Genome-Modifying EnzymesNSFChemistry Section2022$537,317August 1, 2022July 31, 2026Kabirul Islamnsf.gov
Development of Native-Like Peptoid Macrodiscs and Multidimensional Solid-State NMR Methods for Structural Studies of Membrane ProteinsNSFChemistry Section2024$534,974July 1, 2024June 30, 2027Alexander Nevzorovnsf.gov
Boronic Acid Methods for Chemical Manipulation of BiomacromoleculesNSFChemistry Section2022$531,000September 1, 2022August 31, 2025Zachary Ballnsf.gov
Collaborative Research: Evolution and Chemical Biology of Base Excision RepairNSFChemistry Section2026$529,984August 15, 2026July 31, 2029Sheila S Davidnsf.gov
Synthetic Biology Approaches to Selective Amino Acid Modification and IncorporationNSFChemistry Section2022$528,000September 1, 2022August 31, 2025Michelle Changnsf.gov
Structural and Functional Properties of Enzymes Involved in Persulfide DegradationNSFChemistry Section2025$525,000September 1, 2025August 31, 2028Holly R Ellisnsf.gov
Leveraging releasable aryl diazonium ions to probe biochemical systemsNSFChemistry Section2023$517,703July 1, 2023June 30, 2027John C Jewettnsf.gov
Collaborative Research: Chemical Biology of DNA repairNSFDivision Of Chemistry2022$510,255September 1, 2022August 31, 2025Sheila S Davidnsf.gov
The Role of Thioamides in Natural and Designed ProteinsNSFChemistry Section2022$510,000July 1, 2022June 30, 2026Ernest J Peterssonnsf.gov
New Catalysts by Cofactor ModulationNSFDivision Of Chemistry2022$510,000July 1, 2022June 30, 2025Steven E Rokitansf.gov
Deciphering Post-Translationally Modified Peptides with Arrayed Synthetic ReceptorsNSFChemistry Section2023$510,000August 1, 2023July 31, 2027Richard J Hooleynsf.gov
Development of Photoswitchable Nucleotides to Control RNA BiochemistryNSFChemistry Section2025$510,000September 1, 2025August 31, 2028Jia Shengnsf.gov
Next Generation Protein Arylation ReagentsNSFChemistry Section2026$510,000August 15, 2026July 31, 2029Samuel G Awuahnsf.gov
CAS-Biophysical Studies of Lipid Droplets and their Associate ProteinsNSFChemistry Section2022$506,581September 1, 2022August 31, 2026Kerney J Glovernsf.gov
CAREER: Revealing the interaction mechanisms of PICK1 using multiscale modelingNSFChemistry Section2023$500,369November 1, 2023October 31, 2028Yi Hensf.gov
Expanding and Improving the Toolkit of Mitochondrial Calcium Uptake InhibitorsNSFChemistry Section2024$500,000August 1, 2024July 31, 2027Justin J Wilsonnsf.gov
CAREER: Synthetic Protein Switches for Expanding the Folding CodeNSFChemistry Section2025$500,000August 1, 2025July 31, 2030Nicholas Truexnsf.gov
Development of Cell-Penetrating MonobodiesNSFChemistry Section2024$498,000March 1, 2024February 28, 2027Qing Linnsf.gov
CDS&E: High-throughput Computational Workflow for Elucidating the Origin of Lasso Peptide HandednessNSFChemistry Section2025$497,936September 1, 2025August 31, 2028Zhongyue Yangnsf.gov
CAREER: Engineering and In Vitro Evolution of XNAs as a Platform for Protein Recognition and Aggregation ControlNSFChemistry Section2026$497,504August 15, 2026July 31, 2031Lijun Zhounsf.gov
Elucidating the Hidden Steps of Replicative DNA Synthesis by Time - Resolved X - ray CrystallographyNSFChemistry Section2025$497,092February 1, 2025January 31, 2028John Chaputnsf.gov
Collaborative Research: Unraveling the Initial Charge Separation Mechanism in Photosystem I: A Synergistic ApproachNSFChemistry Section2023$495,983September 15, 2023August 31, 2026Lyudmila V Slipchenkonsf.gov
Controlling Protein Post-translational Modification by Separating Affinity and Catalysis in Designer EnzymesNSFDivision Of Chemistry2022$495,000June 1, 2022May 31, 2025Albert Bowersnsf.gov
Cys-Tyr Cofactor in Iron and Copper ProteinsNSFChemistry Section2022$495,000October 1, 2022September 30, 2026Aimin Liunsf.gov
Investigation of Two New Protein Post-Translational Modifications Derived from a Key Metabolite in Valine MetabolismNSFChemistry Section2022$494,550December 15, 2022January 31, 2027Y George Zhengnsf.gov
Azole Antifungals Coordinate Metals and Create Reactive Oxygen Species That Damage DNA and Cause Chromosomal InstabilityNSFChemistry Section2022$492,000July 15, 2022June 30, 2027Julia L Brumaghimnsf.gov
Riboflavinator: a molecular machine for efficient riboflavin biosynthesisNSFChemistry Section2022$486,057December 15, 2022March 31, 2027Audrey L Lambnsf.gov
CAREER: Mechanistic Investigation of Covalent Protein Targeting via Genetically Encoded ReactivityNSFChemistry Section2026$482,821September 1, 2026August 31, 2031Weixin Tangnsf.gov
Collaborative Research: Mechanistic Insights into Substrate Transformations by the Complex Iron-Sulfur Molybdoenzyme (CISM) FamilyNSFChemistry Section2026$475,056September 1, 2026August 31, 2029Partha Basunsf.gov
Photoswitchable DNA-Encoded Libraries: A Discovery Platform for Light-Controlled Protein BindersNSFChemistry Section2026$472,949August 15, 2026July 31, 2029Raphael M Franzininsf.gov
Collaborative Research: Ethylene-Forming EnzymeNSFChemistry Section2022$471,290September 1, 2022August 31, 2028Christo Z Christovnsf.gov
Collaborative Research: Evolution and Chemical Biology of Base Excision RepairNSFChemistry Section2026$470,014August 15, 2026July 31, 2029Martin P Horvathnsf.gov
Collaborative Research: Nucleobase-Modified PNA for Sequence Selective Triple-Helical Recognition of Non-Coding RNANSFChemistry Section2024$465,000August 15, 2024July 31, 2027Eriks Roznersnsf.gov
Collaborative Research: Probing the role of chemical modifications on structure, folding, and dynamics of tRNA isodecodersNSFChemistry Section2025$460,000September 1, 2025August 31, 2028Harish Vashisthnsf.gov
Phage Display of Multicyclic PeptidesNSFChemistry Section2022$459,001September 1, 2022May 31, 2026Jianmin Gaonsf.gov
Iron-sulfur Clusters as Biological Sensors: Mechanistic Investigations by Synthetic Modeling StudiesNSFChemistry Section2022$450,223July 1, 2022December 31, 2026Eunsuk Kimnsf.gov
Model Systems for Studying Carbohydrate-Carbohydrate InteractionsNSFChemistry Section2022$450,000September 1, 2022August 31, 2027Amit Basunsf.gov
Using Glycodendrimers to Elucidate the Importance of Multivalency in the Structures and Functions of GalectinsNSFChemistry Section2022$450,000November 1, 2022October 31, 2026Mary J Cloningernsf.gov
Collaborative Research: Unraveling the Initial Charge Separation Mechanism in Photosystem I: A synergistic ApproachNSFChemistry Section2023$450,000September 15, 2023August 31, 2027Wu Xunsf.gov
Collaborative Research: Biochemical and Spectroscopic Studies of Mononuclear Iron Enzyme Catalyzed C-X Bond Forming and Cleaving Reactions using O2 as the only Co-SubstrateNSFChemistry Section2024$450,000August 1, 2024July 31, 2027Yisong Guonsf.gov
Collaborative Research: Biochemical and Spectroscopic Studies of Mononuclear Iron Enzyme Catalyzed C-X Bond Forming and Cleaving Reactions using O2 as the only Co-SubstrateNSFChemistry Section2024$450,000August 1, 2024July 31, 2027Wei-chen Changnsf.gov
RUI: Biochemical Comparison of Type II Polyketide Biosynthetic Enzymes Across Phyla for Expanded Access to Chemical DiversityNSFChemistry Section2022$447,000December 15, 2022February 28, 2027Louise Charkoudiannsf.gov
Glyoxal-Based Caging for Temporal Control of Nucleic Acid FunctionNSFDivision Of Chemistry2022$444,812July 1, 2022January 31, 2023Jennifer M Heemstransf.gov
Glyoxal-Based Caging for Temporal Control of Nucleic Acid FunctionNSFChemistry Section2023$444,812December 15, 2022June 30, 2026Jennifer M Heemstransf.gov
Collaborative Research: Conformational Dynamics and Protein Evolution in the Protein Tyrosine Phosphatase Superfamily.NSFChemistry Section2024$440,262July 1, 2024June 30, 2027Sean J Johnsonnsf.gov
Measuring and Manipulating how Proteins Control their Net Charge: Redox Enzymes, Crowded Enzymes, and Aggregated Proteins.NSFDivision Of Chemistry2022$440,000September 1, 2022February 28, 2026Bryan Shawnsf.gov
Chemical Tools for Precision Metabolic Labeling and Detection of Terpenes and Prenylated MoleculesNSFDivision Of Chemistry2022$436,846July 1, 2022June 30, 2025Joshua A Baccilensf.gov
Collaborative Research: Conformational Dynamics and Protein Evolution in the Protein Tyrosine Phosphatase Superfamily.NSFChemistry Section2024$431,392July 1, 2024June 30, 2027Shina C Kamerlinnsf.gov
Collaborative Research: De Novo Protein Constructs for Photosynthetic Energy TransductionNSFChemistry Section2025$426,000September 1, 2025August 31, 2028William F DeGradonsf.gov
New Multifunctional Bioorthogonal ProbesNSFDivision Of Chemistry2022$423,000July 1, 2022December 31, 2025Jennifer M Schomakernsf.gov
New Chemical Tools for Advancing Lipid Metabolic LabelingNSFChemistry Section2023$421,521July 15, 2023June 30, 2027Michael D Bestnsf.gov
Collaborative Research: Interfacing Students at Three Universities to Elucidate Enzymatic Transformations of Guanide Compounds that Impact Health and the EnvironmentNSFChemistry Section2022$421,429June 1, 2022May 31, 2026Martin St Mauricensf.gov
RUI: Allosteric Activators of the Sarco/Endoplasmic Reticulum Calcium ATPaseNSFChemistry Section2023$420,201September 15, 2023August 31, 2027Stefan Paulansf.gov
CAREER: To Be Nitrated or To Be Crosslinked: Illuminating Unusual Cytochrome P450 Enzymes in RiPP BiosynthesisNSFChemistry Section2026$420,000September 1, 2026August 31, 2031Yifan Wangnsf.gov
RUI: Atomic Level Mechanism of NIS SynthetasesNSFChemistry Section2025$417,066September 1, 2025August 31, 2028Katherine M Hoffmannnsf.gov
Collaborative Research: Exploring the Mechanisms, Functional Diversity, and Conformational Dynamics of Flavin-dependent MonooxygenasesNSFChemistry Section2025$412,906January 1, 2025December 31, 2027John J Tannernsf.gov
Collaborative Research: Chemical Tools to Elucidate Glycolipid Biosynthesis and Transport in the CorynebacterineaeNSFChemistry Section2023$406,500July 1, 2023June 30, 2027Benjamin M Swartsnsf.gov
Collaborative Research: Chemical Tools to Elucidate Glycolipid Biosynthesis and Transport in the CorynebacterineaeNSFChemistry Section2023$406,500July 1, 2023June 30, 2027Mary C Jacksonnsf.gov
Mechanisms of Adaptation of Extracellular Nucleases to Extreme ConditionsNSFChemistry Section2023$405,960September 1, 2023August 31, 2026Catherine A Royernsf.gov
RUI: Sugar Probes to Track Utilization, Uptake, and Processing of Monosaccharides by BacteriaNSFChemistry Section2023$402,000April 15, 2023March 31, 2028Danielle H Dubensf.gov
Collaborative Research: Interfacing Students at Three Universities to Elucidate Enzymatic Transformations of Guanide Compounds that Impact Health and the EnvironmentNSFDivision Of Chemistry2022$398,437June 1, 2022May 31, 2025Lawrence P Wackettnsf.gov
Collaborative Research: Chemical Biology of DNA repairNSFDivision Of Chemistry2022$393,263September 1, 2022August 31, 2025Martin P Horvathnsf.gov
Collaborative Research: CAS: Mechanistic Studies on Fe-Type Nitrile Hydration CatalystsNSFChemistry Section2022$391,121September 1, 2022August 31, 2026Brian Bennettnsf.gov
Metal-mediated ligand affinity chemistryNSFDivision Of Chemistry2022$390,000July 1, 2022June 30, 2025Samuel G Awuahnsf.gov
RUI: Expanding the chemical biology toolbox for studying peptidoglycan metabolismNSFChemistry Section2024$390,000May 1, 2024April 30, 2027Christopher W Reidnsf.gov
Chiral Sum-Frequency Generation Microscopy: Mapping Chiral Macromolecular Assemblies in Cells and TissuesNSFChemistry Section2024$388,983July 1, 2024June 30, 2027Eric O Potmansf.gov
Computational Studies on the Modulation of Peptide-lipid Interactions by GlycosaminoglycansNSFDivision Of Chemistry2022$384,000July 1, 2022December 31, 2025Silvina Matysiaknsf.gov
CAREER: BIOCATALYTIC SYNTHESIS OF ENANTIOENRICHED NITROGEN-CONTAINING HETEROCYCLESNSFDivision Of Chemistry2023$365,317September 15, 2023May 31, 2025Todd K Hysternsf.gov
Collaborative Research: Nucleobase-Modified PNA for Sequence Selective Triple-Helical Recognition of Non-Coding RNANSFChemistry Section2024$360,000August 15, 2024August 31, 2027James A MacKaynsf.gov
RUI: Exploring the Utility of Antiparallel Triplex-forming CNA Dimers as Sequence-specific DNA Major Groove Binding AgentsNSFChemistry Section2025$345,248September 1, 2025August 31, 2028Thomas Minehannsf.gov
RUI: Chemoenzymatic fluorination of aromatic compoundsNSFChemistry Section2024$339,471May 1, 2024April 30, 2027Stephen E Nybonsf.gov
RUI: Exploring the Structural Basis of Dynein RegulationNSFChemistry Section2026$334,962August 15, 2026July 31, 2029Nikolaus M Loeningnsf.gov
Collaborative Research: Mechanistic Insights into Substrate Transformations by the Complex Iron-Sulfur Molybdoenzyme (CISM) FamilyNSFChemistry Section2026$334,935September 1, 2026August 31, 2029Jarett M Wilcoxennsf.gov
Collaborative Research: Probing the role of chemical modifications on structure, folding, and dynamics of tRNA isodecodersNSFChemistry Section2025$320,000September 1, 2025August 31, 2028Esteban A Orellana Vinuezansf.gov
CAREER: Next-Generation Flow Cytometry - A New Approach to Cell HeterogeneityNSFChemistry Section2024$316,710April 1, 2024April 30, 2026Ku-Lung Hsunsf.gov
Collaborative Research: RUI: Interrogating Catalytic Efficiency through Kinetic, Structural and Small-Molecule Guided Investigation of L-DOPA 2,3-Dioxygenases.NSFChemistry Section2025$315,000August 1, 2025July 31, 2028Keri L Colabroynsf.gov
Collaborative Research: RUI: An In-depth Characterization of Divalent Cadmium Binding to Human Cardiac Troponin C and the Impact on Subsequent Protein InteractionsNSFChemistry Section2022$312,108September 1, 2022August 31, 2026Anne Marie Spuchesnsf.gov
Collaborative Research: Combining Theory and Experiment to Understand the First Photophysical Events in the Photoactivation of the Orange Carotenoid ProteinNSFChemistry Section2022$308,978September 1, 2022August 31, 2027Warren F Becknsf.gov
RUI: Mechanism of Biomolecule Stabilization in Solution by Tardigrade-specific CAHS ProteinsNSFChemistry Section2024$306,783July 15, 2024June 30, 2027Brooke E Christiannsf.gov
CAREER: Geometric and Electronic Contributions to Bio-inspired Reactivities of Heme-superoxide IntermediatesNSFChemistry Section2024$284,000April 1, 2024May 31, 2026Gayan B Wijeratnensf.gov
Elucidating mechanisms of biological hydrogen conversion through model metalloenzymesNSFChemistry Section2024$280,990April 1, 2024September 30, 2026Hannah S Shafaatnsf.gov
Proteomic Characterization of EV RNA-Binding Proteome Landscape in Cell-Cell CommunicationNSFChemistry Section2024$280,000September 1, 2024August 31, 2027Weiguo A Taonsf.gov
Collaborative Research: Combining Theory and Experiment to Understand the First Photophysical Events in the Photoactivation of the Orange Carotenoid ProteinNSFChemistry Section2022$277,074September 1, 2022August 31, 2026Jose A Gasconnsf.gov
CAREER: Optically Controlled Protein Proximity LabellingNSFDivision Of Chemistry2023$270,000November 1, 2022December 31, 2025Michael Taylornsf.gov
The Bioorganic Chemistry of Electrophilic Sulfur in Cysteine Post-Translational ModificationsNSFDivision Of Chemistry2023$264,696July 15, 2023September 30, 2024Kate S Carrollnsf.gov
Ruthenium Coordination Complexes as Tools for Studying Biological Hydrogen SulfideNSFDivision Of Chemistry2024$249,793July 1, 2024June 30, 2025Justin J Wilsonnsf.gov
LEAPS-MPS: Specificity and Mechanism of Azoreductases Versus Nonenzymatic Hydrogen Sulfide Reduction of Azo Compounds Due to the Human Gut MicrobiomeNSFChemistry Section2025$248,084September 1, 2025August 31, 2027Tyler M Stacknsf.gov
RUI: Re-engineering Ring-Cleaving Dioxygenases for Activity Towards Novel SubstratesNSFChemistry Section2022$240,000July 15, 2022September 30, 2026Timothy E Machonkinnsf.gov
The Bioorganic Chemistry of Electrophilic Sulfur in Cysteine Post-Translational ModificationsNSFChemistry Section2024$234,925August 1, 2024June 30, 2027Kate S Carrollnsf.gov
Collaborative Research: CAS: Mechanistic Studies on Fe-Type Nitrile Hydration CatalystsNSFDivision Of Chemistry2022$208,879September 1, 2022August 31, 2025Richard C Holznsf.gov
Ruthenium Coordination Complexes as Tools for Studying Biological Hydrogen SulfideNSFDivision Of Chemistry2022$200,207July 1, 2022September 30, 2024Justin J Wilsonnsf.gov
Inorganic-aptamer hybrids for live cell imagingNSFDivision Of Chemistry2023$180,330June 15, 2023December 31, 2025Edith C Glazernsf.gov
Collaborative Research: RUI: Interrogating Catalytic Efficiency through Kinetic, Structural and Small-Molecule Guided Investigation of L-DOPA 2,3-Dioxygenases.NSFChemistry Section2025$180,000August 1, 2025July 31, 2028Larryn W Petersonnsf.gov
RUI: Determining Non-Symbiotic Hemoglobin Function in PlantsNSFChemistry Section2025$166,000September 1, 2025August 31, 2028Ryan Sturmsnsf.gov
Allosteric Modulation in Nicotinic Acetylcholine ReceptorsNSFDivision Of Chemistry2022$123,674July 1, 2022June 30, 2025Mark M Levandoskinsf.gov
Collaborative Research: Interfacing Students at Three Universities to Elucidate Enzymatic Transformations of Guanide Compounds that Impact Health and the EnvironmentNSFDivision Of Chemistry2022$118,384June 1, 2022May 31, 2025Betsy M Martinez-Vaznsf.gov
Collaborative Research: RUI: An In-depth Characterization of Divalent Cadmium Binding to Human Cardiac Troponin C and the Impact on Subsequent Protein InteractionsNSFChemistry Section2022$118,157September 1, 2022August 31, 2026Jason Hurlbertnsf.gov
Collaborative Research: CDS&E: Computational Investigation of Solvent Effects on Enzyme CatalysisNSFDivision Of Chemistry2022$96,219March 15, 2022July 31, 2023Gerardo A Cisnerosnsf.gov
CAREER: Advancing Proximity Labeling Mass Spectrometry to Characterize Neuronal Mitochondrial DynamicsNSFDivision Of Chemistry2023$77,443July 1, 2023June 30, 2025Ling Haonsf.gov
RUI: Biosynthetic Diversification of Diketopiperazine Natural ProductsNSFDivision Of Chemistry2024$61,703August 1, 2024July 31, 2025Amy L Lanensf.gov
CAREER: Lipid Regulation of Receptor Tyrosine KinasesNSFDivision Of Chemistry2023$59,220December 15, 2022April 30, 2024Adam W Smithnsf.gov
Deeper Understanding of Factors that Fine-tune Redox Potentials of MetalloproteinsNSFDivision Of Chemistry2022$29,317October 1, 2021May 31, 2022Yi Lunsf.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
University of Michigan at Ann ArborAnn Arbor, MI0$06$3.7 million
University of UtahSalt Lake City, UT0$06$3.2 million
Wayne State UniversityDetroit, MI0$04$3.1 million
University of Texas at AustinAustin, TX0$06$2.8 million
Emory UniversityAtlanta, GA0$04$2.7 million
Princeton UniversityPrinceton, NJ0$04$2.7 million
University of California-Santa BarbaraSanta Barbara, CA0$05$2.6 million
University of California Los AngelesLos Angeles, CA0$04$2.6 million
Johns Hopkins UniversityBaltimore, MD0$03$2.5 million
University of California-IrvineIrvine, CA0$04$2.1 million
Purdue UniversityWest Lafayette, IN0$04$2.1 million
University of Maryland, College ParkCollege Park, MD0$03$1.9 million
University of California-BerkeleyBerkeley, CA0$03$1.9 million
University of Wisconsin-MadisonMadison, WI0$03$1.8 million
North Carolina State UniversityRaleigh, NC0$04$1.8 million
Vanderbilt UniversityNashville, TN0$02$1.8 million
Univ of North Carolina Chapel HillChapel Hill, NC0$03$1.8 million
Colorado State UniversityFort Collins, CO0$03$1.8 million
University of DelawareNewark, DE0$02$1.8 million
University of Tennessee KnoxvilleKnoxville, TN0$03$1.5 million
University of KentuckyLexington, KY0$03$1.5 million
Stanford UniversityStanford, CA0$01$1.5 million
University of DenverDenver, CO0$02$1.5 million
New York UniversityNew York, NY0$02$1.4 million
University of ChicagoChicago, IL0$02$1.4 million
Colorado School of MinesGolden, CO0$03$1.3 million
University of South Carolina at ColumbiaColumbia, SC0$02$1.3 million
Wake Forest UniversityWinston Salem, NC0$02$1.2 million
University of California-RiversideRiverside, CA0$02$1.2 million
Scripps Research Institute, theLa Jolla, CA0$02$1.2 million
Georgia Tech Research CorporationAtlanta, GA0$02$1.1 million
Board of Regents, NSHE, obo University of Nevada, RenoReno, NV0$02$1.1 million
University of MinnesotaMinneapolis, MN0$02$1.1 million
SUNY at BuffaloAmherst, NY0$02$1 million
University of California at DavisDavis, CA0$02$1 million
Boston CollegeChestnut Hill, MA0$02$1 million
University of PennsylvaniaPhiladelphia, PA0$02$1 million
University of Texas at San AntonioSan Antonio, TX0$02$981,057
University of Missouri-ColumbiaColumbia, MO0$02$973,069
University of HawaiiHonolulu, HI0$01$970,600
University of FloridaGainesville, FL0$02$964,696
Yale UniversityNew Haven, CT0$01$960,000
Duke UniversityDurham, NC0$01$924,000
University of Georgia Research Foundation IncAthens, GA0$02$914,550
Michigan State UniversityEast Lansing, MI0$02$902,737
Brown UniversityProvidence, RI0$02$900,223
Northeastern UniversityBoston, MA0$01$869,536
University of Nebraska-LincolnLincoln, NE0$01$847,296
East Carolina UniversityGreenville, NC0$02$837,108
University of MississippiUniversity, MS0$01$827,000
University of California, San DiegoLa Jolla, CA0$01$820,000
University of HoustonHouston, TX0$01$813,751
Marquette UniversityMilwaukee, WI0$02$812,550
Syracuse UniversitySyracuse, NY0$01$803,672
Columbia UniversityNew York, NY0$01$801,590
Tufts UniversityMedford, MA0$01$800,000
Rutgers University NewarkNewark, NJ0$01$799,246
Pennsylvania State Univ University ParkUniversity Park, PA0$01$798,000
University of Texas at DallasRichardson, TX0$02$796,219
University of ArizonaTucson, AZ0$02$787,703
Western Michigan UniversityKalamazoo, MI0$01$757,000
University of South FloridaTampa, FL0$01$724,746
Northwestern University at ChicagoChicago, IL0$01$705,000
Temple Univ of the CommonwealthPhiladelphia, PA0$01$700,000
Saint Louis UniversitySaint Louis, MO0$01$695,000
University of MiamiCoral Gables, FL0$01$670,000
University of Vermont & ST Agric CollegeBurlington, VT0$01$665,769
California Institute of TechnologyPasadena, CA0$01$625,000
University of Oregon EugeneEugene, OR0$01$622,797
Oklahoma State UniversityStillwater, OK0$01$622,000
Trustees of Boston UniversityBoston, MA0$01$614,728
Iowa State UniversityAmes, IA0$01$599,760
Miami UniversityOxford, OH0$01$577,656
Missouri University of Science and TechnologyRolla, MO0$01$572,018
Loyola University of ChicagoChicago, IL0$01$567,000
Texas A&M UniversityCollege Station, TX0$01$566,966
Arizona State UniversityScottsdale, AZ0$01$555,000
University of Illinois at ChicagoChicago, IL0$01$540,000
Ohio State UniversityColumbus, OH0$01$539,215
University of Pittsburgh at PittsburghPittsburgh, PA0$01$537,317
William Marsh Rice UniversityHouston, TX0$01$531,000
SUNY at AlbanyAlbany, NY0$01$510,000
Lehigh UniversityBethlehem, PA0$01$506,581
University of New MexicoAlbuquerque, NM0$01$500,369
Clemson UniversityClemson, SC0$01$492,000
Indiana UniversityBloomington, IN0$01$475,056
Michigan Technological UniversityHoughton, MI0$01$471,290
SUNY at BinghamtonBinghamton, NY0$01$465,000
University of New HampshireDurham, NH0$01$460,000
Montana State UniversityBozeman, MT0$01$450,000
University of Louisiana at LafayetteLafayette, LA0$01$450,000
Carnegie Mellon UniversityPittsburgh, PA0$01$450,000
Haverford CollegeHaverford, PA0$01$447,000
Washington UniversitySaint Louis, MO0$01$444,812
Utah State UniversityLogan, UT0$01$440,262
Baylor UniversityWaco, TX0$01$440,000
University of California, San FranciscoSan Francisco, CA0$01$426,000
University Enterprises, IncorporatedSacramento, CA0$01$420,201
California Lutheran UniversityThousand Oaks, CA0$01$417,066
Central Michigan UniversityMount Pleasant, MI0$01$406,500

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
20260$027$13,882,783
20250$053$26,151,507
20240$052$24,220,690
20230$057$22,085,473
20220$061$25,263,570

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Geometric AnalysisPD-22-1265NSF47.049November 3, 2026Not listedSame assistance listing 47.049 as 206 awards here
TopologyPD-22-1267NSF47.049November 3, 2026Not listedSame assistance listing 47.049 as 206 awards here
Unlocking Dataset Value for AI-Enabled Scientific Discovery (AI Datasets)26-512NSF47.049November 4, 2026Not listedSame assistance listing 47.049 as 206 awards here
Astronomy and Astrophysics Research Grants22-624NSF47.049November 16, 2026Not listedSame assistance listing 47.049 as 206 awards here
Applied MathematicsPD-16-1266NSF47.049November 16, 2026Not listedSame assistance listing 47.049 as 206 awards here
Plasma PhysicsPD-23-1242NSF47.049November 16, 2026Not listedSame assistance listing 47.049 as 206 awards here
National Science Foundation Translation to Practice (NSF TTP)25-540NSF47.049November 17, 2026$2 millionSame assistance listing 47.049 as 206 awards here
Computational MathematicsPD-16-1271NSF47.049December 1, 2026$1.2 millionSame assistance listing 47.049 as 206 awards here
StatisticsPD-18-1269NSF47.049December 15, 2026Not listedSame assistance listing 47.049 as 206 awards here
Training-based Workforce Development for Advanced Cyberinfrastructure23-520NSF47.049January 21, 2027$1 millionSame assistance listing 47.049 as 206 awards here
Security, Privacy, and Trust in Cyberspace (NSF SaTC)25-515NSF47.049January 25, 2027$1.2 millionSame assistance listing 47.049 as 206 awards here
EPSCoR Research Infrastructure Improvement Program: Focused EPSCoR Collaborations (FEC)24-573NSF47.049January 26, 2027$1.5 millionSame assistance listing 47.049 as 206 awards here
Mathematical Sciences Infrastructure ProgramPD-20-1260NSF47.049February 2, 2027Not listedSame assistance listing 47.049 as 206 awards here
GROWING CONVERGENCE RESEARCH (GCR)24-527NSF47.049February 8, 2027$3.6 millionSame assistance listing 47.049 as 206 awards here
Mid-scale Research Infrastructure-124-598NSF47.049February 8, 2027$20 millionSame assistance listing 47.049 as 206 awards here
EMERGING FRONTIERS IN RESEARCH AND INNOVATION (EFRI-2026/27): Wave-Based Computing ( EFRI-WBC)26-524NSF47.049February 11, 2027Not listedSame assistance listing 47.049 as 206 awards here
Pathways to Enable Secure Open-Source Ecosystems (PESOSE)26-506NSF47.049March 2, 2027Not listedSame assistance listing 47.049 as 206 awards here
NSF National Quantum Virtual Laboratory (NQVL)24-586NSF47.049April 6, 2027Not listedSame assistance listing 47.049 as 206 awards here
EPSCoR Research Infrastructure Improvement (RII): EPSCoR Research Fellows24-528NSF47.049April 13, 2027Not listedSame assistance listing 47.049 as 206 awards here
Findable Accessible Interoperable Reusable Open Science (FAIROS)25-533NSF47.049April 14, 2027Not listedSame assistance listing 47.049 as 206 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.