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Data / Research funding / Innovation: Research Methods

NSF program Innovation: Research Methods (166Y00): 18 awards, $11.3M to 17 organizations

18 NSF awards ($11.3M) under the program element Innovation: Research Methods (166Y00) to 17 organizations, fiscal years 2022 to 2026, read 2026-11-03.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

Program element code
166Y00
Directorate
Directorate for Biological Sciences
Division
Innovation Tools, Informatics, & Functional Genomics

Awards

18 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Tools4Cells: TimeCLIP technology to enable time-resolved detection of protein-RNA interactionsNSFInnovation Tools, Informatics, & Functional Genomics2026$1,000,000September 1, 2026August 31, 2029Jernej Murnnsf.gov
IIBR Research Methods: Developing novel methods to sequence, visualize and analyze GlycoRNAs in diverse organismsNSFInnovation Tools, Informatics, & Functional Genomics2024$997,082August 1, 2024July 31, 2027Yi Lunsf.gov
Tools4Cells: Development of self-amplifying RNA systems for bacterial protein synthesisNSFInnovation Tools, Informatics, & Functional Genomics2025$986,944September 1, 2025August 31, 2028Pedro J Alvareznsf.gov
Highly-Multiplexed Fluorescence with DNA-Nanoruler Spectral BarcodesNSFInnovation Tools, Informatics, & Functional Genomics2025$926,816September 15, 2025August 31, 2028Marc R Birtwistlensf.gov
CAREER: Multiplexed mRNA detection at nanometer resolutionNSFInnovation Tools, Informatics, & Functional Genomics2026$874,717July 1, 2026June 30, 2031Diana P Goncalves Schmidtnsf.gov
UKRI/BBSRC-NSF/BIO: Interpretable and Noise-Robust Machine Learning for NeurophysiologyNSFInnovation Tools, Informatics, & Functional Genomics2023$851,348October 1, 2023March 31, 2028Mohsen Imaninsf.gov
IIBR Research Methods: Probing the structure, abundance, dynamics, and function of protein complexes within their cellular environmentNSFInnovation Tools, Informatics, & Functional Genomics2023$737,906October 1, 2023September 30, 2026Valerica Raicunsf.gov
Transforming Protein Engineering Infrastructure: Using PicoShells for Rapid Directed Evolution of Complex FunctionsNSFInnovation Tools, Informatics, & Functional Genomics2024$730,000August 1, 2024July 31, 2027Dino Di Carlonsf.gov
CAREER: Discovering the Spatial Modes of Tissue Perturbation with Volumetric DNA MicroscopyNSFInnovation Tools, Informatics, & Functional Genomics2026$688,712September 1, 2026August 31, 2031Joshua Weinsteinnsf.gov
CAREER: Revealing the Connection between Invasive Species Distributions and Disturbance Events Using Satellite Remote SensingNSFInnovation Tools, Informatics, & Functional Genomics2026$591,565August 1, 2026July 31, 2031Susan K Meerdinknsf.gov
Collaborative Research: Research Infrastructure: Moth Monitoring 2.0: Developing an integrated monitoring framework across life stages to understand insect declinesNSFInnovation Tools, Informatics, & Functional Genomics2025$569,960September 15, 2025August 31, 2028Allen H Hurlbertnsf.gov
Collaborative Research: Two-photon DeepSpiral super-resolution imaging of in vivo molecular dynamics in deep tissueNSFInnovation Tools, Informatics, & Functional Genomics2026$491,215August 15, 2026July 31, 2029Emily Gibsonnsf.gov
Collaborative Research: Research Infrastructure: Moth Monitoring 2.0: Developing an integrated monitoring framework across life stages to understand insect declinesNSFInnovation Tools, Informatics, & Functional Genomics2025$429,998September 15, 2025August 31, 2028Robert P Guralnicknsf.gov
Collaborative Research: Two-photon DeepSpiral super-resolution imaging of in vivo molecular dynamics in deep tissueNSFInnovation Tools, Informatics, & Functional Genomics2026$360,000August 15, 2026July 31, 2029Juliet T Gopinathnsf.gov
Collaborative Research: Two-photon DeepSpiral super-resolution imaging of in vivo molecular dynamics in deep tissueNSFInnovation Tools, Informatics, & Functional Genomics2026$339,612August 15, 2026July 31, 2029Mark Siemensnsf.gov
CAREER: Deep-tissue optical imaging via inverse-scatteringNSFInnovation Tools, Informatics, & Functional Genomics2025$303,958August 15, 2025July 31, 2030Shwetadwip Chowdhurynsf.gov
Collaborative Research: Research Infrastructure: Moth Monitoring 2.0: Developing an integrated monitoring framework across life stages to understand insect declinesNSFInnovation Tools, Informatics, & Functional Genomics2025$230,000September 15, 2025August 31, 2028Mariana Abarcansf.gov
Desiccation-based microbial sample preservation in remote regionsNSFInnovation Tools, Informatics, & Functional Genomics2023$190,467October 1, 2023September 30, 2027Stilianos Loucansf.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
University of Texas at AustinAustin, TX0$02$1.3 million
University of California-RiversideRiverside, CA0$01$1 million
William Marsh Rice UniversityHouston, TX0$01$986,944
Clemson UniversityClemson, SC0$01$926,816
Kent State UniversityKent, OH0$01$874,717
University of California-IrvineIrvine, CA0$01$851,348
University of Wisconsin-MilwaukeeMilwaukee, WI0$01$737,906
University of California Los AngelesLos Angeles, CA0$01$730,000
University of ChicagoChicago, IL0$01$688,712
University of IowaIowa City, IA0$01$591,565
Univ of North Carolina Chapel HillChapel Hill, NC0$01$569,960
University of Colorado DenverAurora, CO0$01$491,215
University of FloridaGainesville, FL0$01$429,998
University of Colorado at BoulderBoulder, CO0$01$360,000
University of DenverDenver, CO0$01$339,612
Smith CollegeNorthampton, MA0$01$230,000
University of Oregon EugeneEugene, OR0$01$190,467

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
20260$08$4,400,369
20250$07$4,136,459
20240$04$2,084,657
20230$03$678,815

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Unlocking Dataset Value for AI-Enabled Scientific Discovery (AI Datasets)26-512NSF47.074November 4, 2026Not listedSame assistance listing 47.074 as 18 awards here
National Science Foundation Translation to Practice (NSF TTP)25-540NSF47.074November 17, 2026$2 millionSame assistance listing 47.074 as 18 awards here
EPSCoR Research Infrastructure Improvement Program: Focused EPSCoR Collaborations (FEC)24-573NSF47.074January 26, 2027$1.5 millionSame assistance listing 47.074 as 18 awards here
GROWING CONVERGENCE RESEARCH (GCR)24-527NSF47.074February 8, 2027$3.6 millionSame assistance listing 47.074 as 18 awards here
Mid-scale Research Infrastructure-124-598NSF47.074February 8, 2027$20 millionSame assistance listing 47.074 as 18 awards here
Mid-Career Advancement (MCA)22-603NSF47.074March 1, 2027Not listedSame assistance listing 47.074 as 18 awards here
Pathways to Enable Secure Open-Source Ecosystems (PESOSE)26-506NSF47.074March 2, 2027Not listedSame assistance listing 47.074 as 18 awards here
NSF National Quantum Virtual Laboratory (NQVL)24-586NSF47.074April 6, 2027Not listedSame assistance listing 47.074 as 18 awards here
EPSCoR Research Infrastructure Improvement (RII): EPSCoR Research Fellows24-528NSF47.074April 13, 2027Not listedSame assistance listing 47.074 as 18 awards here
Findable Accessible Interoperable Reusable Open Science (FAIROS)25-533NSF47.074April 14, 2027Not listedSame assistance listing 47.074 as 18 awards here
EPSCoR Graduate Fellowship Program (EGFP)24-588NSF47.074June 1, 2027$3.2 millionSame assistance listing 47.074 as 18 awards here
Faculty Early Career Development Program (CAREER)22-586NSF47.074July 28, 2027Not listedSame assistance listing 47.074 as 18 awards here
Research Experiences for Undergraduates (REU)23-601NSF47.074August 18, 2027$500,000Same assistance listing 47.074 as 18 awards here
Postdoctoral Research Fellowships in Biology (PRFB)26-504NSF47.074September 28, 2027Not listedSame assistance listing 47.074 as 18 awards here
Historically Black Colleges and Universities - Excellence in Research (HBCU - EiR)23-598NSF47.074October 19, 2027Not listedSame assistance listing 47.074 as 18 awards here
Plant Biotic Interactions20-576NSF47.074October 5, 2076Not listedSame assistance listing 47.074 as 18 awards here
Core Research in Biological Sciences (BIO Core)26-517NSF47.074October 5, 2076Not listedSame assistance listing 47.074 as 18 awards here
National Science Foundation National Innovation Corps Teams (NSF National I-CorpsTM Teams) Program25-549NSF47.074October 6, 2076Not listedSame assistance listing 47.074 as 18 awards here
Facilitating Research at Primarily Undergraduate Institutions: (RUI and ROA-PUI)14-579NSF47.074October 14, 2076Not listedSame assistance listing 47.074 as 18 awards here
Infrastructure Innovation for Biological Research (Innovation)23-578NSF47.074October 30, 2076$800,000Same assistance listing 47.074 as 18 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.