Data / Research funding / Cellular & Biochem Engineering
NSF program Cellular & Biochem Engineering (149100): 151 awards, $69.3M to 84 organizations
151 NSF awards ($69.3M) under the program element Cellular & Biochem Engineering (149100) to 84 organizations, fiscal years 2022 to 2026, read 2026-11-03.
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- Program element code
- 149100
- Directorate
- Directorate for Engineering
- Division
- Chemical, Bioengineering, Environmental, & Transport Systems
Awards
151 awards in the window.
| Award | Agency | Institute or division | Fiscal year | Amount in window | Start | End | Principal investigator | Source |
|---|---|---|---|---|---|---|---|---|
| Laying the Scientific and Engineering Foundation for Sustainable Cultivated Meat Production | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $2,400,000 | September 15, 2023 | August 31, 2027 | David E Block | nsf.gov |
| EFRI ELiS: Mechanically Adaptive Living Structural Materials | NSF | ENG - Core Programs | 2022 | $2,012,000 | September 1, 2022 | August 31, 2027 | Jingjie Yeo | nsf.gov |
| EFRI ELiS: Desiccatable living cell-based sensors to monitor pollutants and pathogens in built environments | NSF | ENG - Core Programs | 2023 | $2,007,356 | September 1, 2023 | August 31, 2027 | Elisabeth Smela | nsf.gov |
| RECODE: Single Cell-Level Programming of Human Induced Pluripotent Stem Cell Directed Differentiation to Chamber-Specific Cardiomyocytes | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2022 | $1,500,000 | October 1, 2022 | September 30, 2027 | Sean P Palecek | nsf.gov |
| MFB: Characterization of the Biogenesis, Uptake, and Cellular Response to the Ribonucleoprotein Cargoes of Extracellular Vesicles using EV-CLASP | NSF | Molecular Biosciences | 2024 | $1,500,000 | March 1, 2024 | February 28, 2027 | Manuel Ascano | nsf.gov |
| PlantSynBio: Construction of a plant chassis as a platform for biological discoveries and innovations | NSF | Molecular Biosciences | 2023 | $1,042,495 | July 15, 2023 | June 30, 2027 | Carol R Buell | nsf.gov |
| Development of a machine learning pipeline for assisting strain design of nonmodel yeasts | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2022 | $963,286 | October 1, 2022 | September 30, 2027 | Yinjie Tang | nsf.gov |
| Collaborative Research: Closed-loop control of microbial communities by integrating optogenetics and metabolite biosensing | NSF | Molecular Biosciences | 2023 | $947,750 | June 15, 2023 | May 31, 2027 | Jose L Avalos | nsf.gov |
| CAREER: Decoding the Code of Glycan-Collectin Interactions: Computational Engineering of Surfactant Proteins for Tailored Glycan Recognition | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $827,316 | February 1, 2024 | January 31, 2029 | Mona S Minkara | nsf.gov |
| CAREER: Building and controlling the reactivity of a cobalt-porphyrin cofactor | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $794,889 | March 1, 2023 | July 1, 2026 | Andrew R Buller | nsf.gov |
| Engineering autoregulation of the epitranscriptome to track and control stress responses | NSF | Molecular Biosciences | 2022 | $788,204 | July 15, 2022 | June 30, 2026 | Lydia M Contreras | nsf.gov |
| Engineering a fully-integrated translation system for production of proteins and peptides | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $724,140 | June 15, 2024 | May 31, 2028 | Alexander S Mankin | nsf.gov |
| CAREER: Learning and teaching how to program morphogenesis with synthetic genetic circuits, a case study for elongation of mammalian cell spheroids | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2022 | $708,481 | March 15, 2022 | February 28, 2027 | Leonardo Morsut | nsf.gov |
| CAREER: Defining bacterial extracellular vesicle biogenesis and interactions within the host environment | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $671,681 | July 1, 2025 | June 30, 2030 | Hannah Zierden | nsf.gov |
| CAREER: Identification and characterization of low toxicity cryoprotective solutions | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $650,267 | July 15, 2025 | June 30, 2030 | Rebecca Sandlin | nsf.gov |
| Resource allocation through systematic codon usage bias to develop robust engineered HEK293 cells | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2026 | $650,000 | July 1, 2026 | June 30, 2029 | Emmanuel S Tzanakakis | nsf.gov |
| CAREER: Creating and evolving antibodies from scratch in yeast | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2026 | $647,941 | June 1, 2026 | May 31, 2031 | John J Blazeck | nsf.gov |
| CAREER: Understanding and Harnessing Host-derived Small RNAs Against Opportunistic Pathogens | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $636,110 | June 1, 2023 | June 30, 2028 | Jiahe Li | nsf.gov |
| CAREER: Understanding the Impact of Dephosphorylation Kinetics and Adapter Specificity on Synthetic T Cell Receptor Signaling and Function | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $636,088 | February 1, 2024 | January 31, 2029 | Lawrence A Stern | nsf.gov |
| Enhancing cellulase activity through single-molecule imaging and protein engineering as a testbed for understanding and improving enzymatic deconstruction of insoluble substrates | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $629,976 | April 15, 2023 | March 31, 2027 | William O Hancock | nsf.gov |
| GOALI: Leveraging the interconnectedness between mass transfer and cell metabolism for process control of mammalian cell fed-batch and perfusion cultures | NSF | Cell Development & Physiology | 2024 | $629,853 | May 1, 2024 | April 30, 2027 | Sarah W Harcum | nsf.gov |
| Mining and Engineering New Biocatalysts for Sustainable Chemoenzymatic Synthesis | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2026 | $625,000 | September 1, 2026 | August 31, 2029 | Yi Tang | nsf.gov |
| CAREER: Development of novel biocatalyst for consolidated bioprocessing of plastic (CBPP) | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $624,500 | September 1, 2024 | August 31, 2029 | Lahiru N Jayakody | nsf.gov |
| CAREER: Engineering and design of multifunctional protein inhibitors to understand and control complex biological systems | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $621,001 | May 1, 2025 | April 30, 2030 | Maryam Raeeszadeh Sarmazdeh | nsf.gov |
| CAREER: Selectively Reprogramming Proteases through the High-Throughput Discovery of Functional Protein-Protein Interactions. | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $617,187 | February 1, 2023 | January 31, 2028 | Carl A Denard | nsf.gov |
| CAREER: Characterization and Evolution of N-hydroxylase Biocatalysts: Solutions to Catalysis and Remediating Metal Pollution | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $615,416 | March 1, 2023 | February 29, 2028 | Lesley-Ann Giddings | nsf.gov |
| Leveraging Extreme Thermoacidophily for Sustainable Purification of Rare Earth Elements | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $612,653 | May 1, 2025 | April 30, 2028 | Robert M Kelly | nsf.gov |
| CAREER: Regulating the nitrogen cycle via bioelectrochemical fertilizer production and informed food consumption | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2026 | $608,871 | April 1, 2026 | March 31, 2031 | Ruggero Rossi | nsf.gov |
| CAREER: Next-generation protease inhibitor discovery with chemically diversified antibodies | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $608,195 | February 1, 2024 | January 31, 2029 | James A Van Deventer | nsf.gov |
| Collaborative Research: RUI: Elucidating Design Rules for non-NRPS Incorporation of Amino Acids on Polyketide Scaffolds | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $608,177 | April 15, 2023 | March 31, 2028 | Katharine Watts | nsf.gov |
| CAREER: Unraveling the impact of decoupling the carbon metabolism of microbial cell factories on bioproduction | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2022 | $607,598 | February 15, 2022 | January 31, 2027 | Arul Mozhy Varman | nsf.gov |
| CAREER: Deciphering T Cell Reprogramming - Toward Biomanufacturing of Regulatory T Cells | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2026 | $605,420 | May 1, 2026 | April 30, 2031 | Aaron H Morris | nsf.gov |
| CAREER: Enhancing probiotic yeast colonization for stable in situ biomanufacturing | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $604,657 | January 15, 2023 | December 31, 2027 | Nathan C Crook | nsf.gov |
| CAREER: Using Microbial Bioproduction Platform to Elucidate Phytochemical Biosynthesis - Strigolactone as An Example | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $603,048 | January 1, 2024 | August 31, 2027 | Yanran Li | nsf.gov |
| CDS&E: Computational Design of Peptide-Based Biorecognition Elements | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $603,000 | April 15, 2024 | March 31, 2027 | Carol K Hall | nsf.gov |
| Deciphering the Drug Synergy in Pharmacological Rejuvenation of Mesenchymal Stromal Cells | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $601,874 | June 1, 2023 | November 30, 2027 | Neil Y Lin | nsf.gov |
| BMP Signaling and the Robustness of In Vivo Stem Cell Decisions | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $601,071 | August 1, 2023 | July 31, 2027 | Gregory T Reeves | nsf.gov |
| Engineering human stem cell-derived cardiomyocyte maturation using phototunable matrices and machine learning approaches | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $600,000 | September 1, 2024 | August 31, 2027 | Xiaojing Zhang | nsf.gov |
| CAREER: Engineering thermal biosensors for remote control of mammalian cells | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2022 | $595,171 | February 15, 2022 | January 31, 2027 | Lukasz J Bugaj | nsf.gov |
| Saturated fatty acids involved in DNA damage response, mediated by IRE1a, to promote chemotolerance | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $594,628 | July 15, 2023 | June 30, 2027 | Christina Chan | nsf.gov |
| Genetics and Biosynthesis of Novel Forms of Methanobactin | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $592,188 | September 1, 2024 | August 31, 2027 | Jeremy D Semrau | nsf.gov |
| Improving the performance and efficiency of heterotrophic carbon fixation through strain engineering and membrane-based CO2 delivery | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2022 | $588,786 | May 1, 2022 | April 30, 2026 | David Nielsen | nsf.gov |
| Expanding the universe of functional metalloproteins through AI-assisted computational design | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2022 | $585,000 | September 1, 2022 | August 31, 2026 | Parisa Hosseinzadeh | nsf.gov |
| Synergizing Enzyme and Encapsulation Engineering to Develop Superoptimal Biocatalysts | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2022 | $583,993 | October 1, 2022 | September 30, 2027 | Nikhil U Nair | nsf.gov |
| CAREER: Engineering crop plants to metabolize products of CO2 electrolysis to enable food production with artificial photosynthesis | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $582,520 | July 1, 2023 | June 30, 2028 | Robert E Jinkerson | nsf.gov |
| CAREER: Engineering next-generation chimeric antigen receptors for cancer immunotherapy using phospho-proteomics | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2022 | $582,257 | April 1, 2022 | March 31, 2027 | Nicholas A Graham | nsf.gov |
| Semi-Automated Discovery of Synthetic Polymers with Protein Features | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $579,734 | July 15, 2023 | June 30, 2027 | Adam J Gormley | nsf.gov |
| CAREER: Programmable Cell-Matrix Interactions for Regenerative Engineering | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $579,250 | April 1, 2023 | March 31, 2028 | Jonathan M Brunger | nsf.gov |
| CAREER: Metabolic 'doping' to enhance production of biochemicals from sustainable C1 feedstocks | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $575,765 | July 1, 2025 | June 30, 2030 | Benjamin Woolston | nsf.gov |
| CAREER: Origins of Cellular Heterogeneity by Dynamically-linked Multiplexed Imaging | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $574,808 | May 1, 2025 | April 30, 2030 | John W Hickey | nsf.gov |
| CAREER: Investigating the Cellular Electrome as a Biomarker in Red Blood Cell Physiology and Pathology | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2022 | $571,441 | May 15, 2022 | April 30, 2027 | Erin A Henslee | nsf.gov |
| Tuning intercellular cues to regulate paracrine secretion for enhanced neovascularization | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $565,222 | June 15, 2023 | May 31, 2027 | Deborah E Leckband | nsf.gov |
| CAREER: Engineered multispecific antibodies to interrogate and manipulate immune checkpoint protein trafficking | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2022 | $553,546 | February 15, 2022 | January 31, 2028 | Jamie Spangler | nsf.gov |
| CAREER: Micromechanics and Metabolic Properties of Living Interfacial Materials | NSF | Civil, Mechanical, & Manufacturing Innovation | 2024 | $553,156 | October 1, 2023 | March 31, 2027 | Tagbo H Niepa | nsf.gov |
| CAREER: Engineering Light-Controlled Proteins for Sustainable Biomanufacturing | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2026 | $551,083 | September 1, 2026 | August 31, 2031 | Leah Spangler | nsf.gov |
| CAREER: Elucidating the Interaction(s) Between Bacteria and Archaea in a Biocathode | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2022 | $550,000 | August 1, 2022 | July 31, 2027 | Christine M Dykstra | nsf.gov |
| Confined enzyme catalysis in engineered protein nanoreactors | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $550,000 | April 1, 2024 | March 31, 2027 | Tobias W Giessen | nsf.gov |
| CAREER: Developing Electrode Interfaces for Bioelectrochemical Synthesis | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $550,000 | September 1, 2025 | August 31, 2030 | David Hickey | nsf.gov |
| CDS&E: Simulation- and Data-driven Peptide Antibody Design Targeting RBD and non-RBD Epitopes of SARS-CoV-2 Spike Protein | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2022 | $549,351 | September 1, 2022 | May 31, 2023 | Baofu Qiao | nsf.gov |
| CDS&E: Simulation- and Data-driven Peptide Antibody Design Targeting RBD and non-RBD Epitopes of SARS-CoV-2 Spike Protein | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $549,351 | October 1, 2022 | September 30, 2027 | Baofu Qiao | nsf.gov |
| Collaborative Research: Investigating the role and interplay of microenvironment, manufacturing, and metabolism on MSC production of extracellular vesicles | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $547,347 | June 15, 2023 | May 31, 2027 | Ross Marklein | nsf.gov |
| NSF-DBT: Exploiting codon usage bias to maximize the productivity of recombinant Komagataella pastoris | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $545,000 | May 15, 2025 | April 30, 2028 | Nikhil U Nair | nsf.gov |
| CAREER: Development and Application of Novel Methods for Rapid, Facile Chemical Protein Synthesis | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2026 | $542,746 | August 1, 2026 | July 31, 2031 | Timothy M Reichart | nsf.gov |
| CAREER: Defining kinase-driven cellular response networks using single-cell genomics | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2022 | $542,418 | February 15, 2022 | January 31, 2027 | Jose L McFaline-Figueroa | nsf.gov |
| CAREER: Micromechanics and Metabolic Properties of Living Interfacial Materials | NSF | Division of Civil, Mechanical, and Manufacturing Innovation | 2022 | $541,588 | February 1, 2022 | March 31, 2024 | Tagbo H Niepa | nsf.gov |
| NSF-BSF: Molding a Better Future: Filamentous Fungi for Circular Biomanufacturing of Growth Factors | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2026 | $522,776 | August 1, 2026 | July 31, 2029 | Jay D Keasling | nsf.gov |
| CRISPRai-regulated stress response modulation for cell factory engineering | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2026 | $521,194 | July 1, 2026 | June 30, 2029 | Laura Segatori | nsf.gov |
| Logic-gated pro-MMP activation for tumor-specific motility in nanocarriers | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $520,992 | March 15, 2023 | February 29, 2028 | Wilfred Chen | nsf.gov |
| NSF-DBT: Biomolecular Engineering for Critical Mineral Recovery | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $520,855 | May 15, 2025 | April 30, 2028 | Brent L Nannenga | nsf.gov |
| Optogenetic control for metabolic engineering using protein-level regulation | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $519,071 | April 15, 2025 | March 31, 2028 | Mary J Dunlop | nsf.gov |
| CDS&E: Accelerating the Computational Design of Nanoparticle-Protein Interactions via Molecular Simulations, Topological Data Analysis, and Machine Learning | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $510,959 | September 1, 2024 | August 31, 2027 | Reid C Van Lehn | nsf.gov |
| Engineering probiotic yeast to release intracellular molecules into the mammalian gut | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $500,000 | April 15, 2023 | March 31, 2027 | Nathan C Crook | nsf.gov |
| Reprogramming therapy cell secretion capacity | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $500,000 | September 1, 2025 | August 31, 2028 | Michael R Diehl | nsf.gov |
| CAREER: Understanding and Harnessing Host-derived Small RNAs Against Opportunistic Pathogens | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2023 | $499,872 | June 1, 2023 | August 31, 2023 | Jiahe Li | nsf.gov |
| NSF-DBT: Structural and Biophysical Analysis of Evolved Fe(II)/2-Ketoglutarate-Dependent Azidases to Understand and Expand the Substrate Scope of Enzymatic C-H Functionalization | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $494,253 | April 15, 2025 | March 31, 2028 | Jared C Lewis | nsf.gov |
| Collaborative Research: Expanding the substrate range of Clostridium thermocellum to improve understanding of its metabolism | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $479,855 | December 15, 2023 | November 30, 2027 | Daniel G Olson | nsf.gov |
| BioMADE: Driving Cost Reduction in Biomanufacturing Biomaterials from Methane: Engineering Novel Strains to Increase Downstream Processing Efficiency | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $458,552 | October 1, 2025 | September 30, 2027 | Yi Wang | nsf.gov |
| NSF-BSF: Design of Batch Biochemical Oscillators | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $454,056 | August 1, 2024 | July 31, 2027 | Jerome M Fox | nsf.gov |
| BioMADE: Reducing Cost Drivers for Cell Cultured Chocolate | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $450,000 | August 1, 2025 | July 31, 2027 | Karen A McDonald | nsf.gov |
| BioMADE: Development of genomic language models to predict optimal genomes for commercial protein production | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $449,999 | September 1, 2025 | August 31, 2027 | Yun S Song | nsf.gov |
| BioMADE: In-Fermenter Cell Datastreams: Wireless Networks of Free-Floating Microbial-Electronic Sensors | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $449,999 | November 1, 2025 | October 31, 2027 | Rabia T Yazicigil Kirby | nsf.gov |
| Multiplex Next Generation Sequencing of Glycans and Nucleic Acids for Accelerating the Development of Cell Factories and Bioprocesses for Glycoprotein Biomanufacturing | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2026 | $449,962 | February 15, 2026 | July 31, 2028 | Nathan E Lewis | nsf.gov |
| UNDERSTANDING AND CONTROLLING THE COLONIZATION CAPACITIES OF PERSISTER CELLS | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $441,868 | April 1, 2024 | March 31, 2027 | Mehmet A Orman | nsf.gov |
| Mapping and Engineering Structural Coupling Networks that Control Enzyme Catalysis | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2026 | $439,707 | November 1, 2026 | October 31, 2029 | Shuaihua Gao | nsf.gov |
| Divergent binder engineering through multi-pathway protein display | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2026 | $427,467 | May 1, 2026 | April 30, 2029 | Yongku P Cho | nsf.gov |
| Single-cell dynamic analysis to improve the biomanufacturing process for engineering of cell therapy products | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $398,495 | August 1, 2023 | July 31, 2027 | Tania Konry | nsf.gov |
| Engineering GPI-anchored Proteins in Plant Cells for Enhanced Protein Production and Applications | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $394,063 | July 1, 2024 | June 30, 2027 | Jianfeng Xu | nsf.gov |
| RUI: Development of Improved Aromatic-Metabolizing Enzymes Through the Application of Generalizable Enzyme Engineering Strategies | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2026 | $392,649 | May 1, 2026 | April 30, 2029 | Jordan T Froese | nsf.gov |
| Collaborative Research: Synthetic methane fixation cascades based on engineered membrane vesicles for biofuel cell applications | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2022 | $382,376 | September 1, 2022 | August 31, 2025 | Qing Sun | nsf.gov |
| RUI: BIOPOLYMER - BIObricks POLYketide Metabolic EngineeRing platform for unraveling the biosynthesis of higher anthracyclines | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $369,651 | March 1, 2024 | February 28, 2027 | Stephen E Nybo | nsf.gov |
| RUI: Development of New Green-Chemical Catalysts Based on Rieske Dioxygenase Scaffolds Through Directed Evolution | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2022 | $366,434 | April 1, 2022 | March 31, 2026 | Jordan T Froese | nsf.gov |
| CAREER: BIOCATALYTIC SYNTHESIS OF ENANTIOENRICHED NITROGEN-CONTAINING HETEROCYCLES | NSF | Division Of Chemistry | 2023 | $365,317 | September 15, 2023 | May 31, 2025 | Todd K Hyster | nsf.gov |
| Protein Manipulation and Engineering with an Electronic Biochemical Approach | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $357,033 | August 15, 2023 | July 31, 2027 | Yongki Choi | nsf.gov |
| Collaborative Research: Data-driven engineering of the yeast Kluyveromyces marxianus for enhanced protein secretion | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $350,000 | February 15, 2024 | January 31, 2027 | Ian Wheeldon | nsf.gov |
| Collaborative Research: Chimeric Antigen Receptor Engineered Neutrophil Extracellular Vesicles Targeting Glioblastoma | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $350,000 | September 1, 2025 | August 31, 2028 | Yan Li | nsf.gov |
| Collaborative Research: Data-driven engineering of the yeast Kluyveromyces marxianus for enhanced protein secretion | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $349,999 | February 15, 2024 | January 31, 2027 | Nancy A Da Silva | nsf.gov |
| Directed evolution of immobilized enzymes on bacterial spores | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2026 | $343,554 | May 1, 2026 | April 30, 2029 | Seunghyun Sim | nsf.gov |
| Collaborative Research: Deciphering complex phenotypes in bacteria aided by continuous genome shuffling and high throughput analytical technologies | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2022 | $335,214 | January 15, 2022 | December 31, 2025 | Katy C Kao | nsf.gov |
| Collaborative Research: Quantitative analysis and modeling to determine the role of lipids in lymphatic permeability | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $333,567 | August 1, 2024 | July 31, 2027 | Vincenza Cifarelli | nsf.gov |
| Collaborative Research: RUI: Elucidating Design Rules for non-NRPS Incorporation of Amino Acids on Polyketide Scaffolds | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $324,771 | April 15, 2023 | March 31, 2027 | Shaun M McKinnie | nsf.gov |
| Collaborative Research: Deciphering complex phenotypes in bacteria aided by continuous genome shuffling and high throughput analytical technologies | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2022 | $300,000 | January 15, 2022 | December 31, 2025 | Hung-Jen Wu | nsf.gov |
| EAGER: PUF-based Probe Design for Secure Access to DNA Storage | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2023 | $300,000 | February 15, 2023 | January 31, 2026 | Leonidas Bleris | nsf.gov |
| Collaborative Research: Chimeric Antigen Receptor Engineered Neutrophil Extracellular Vesicles Targeting Glioblastoma | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $300,000 | September 1, 2025 | August 31, 2028 | Xiaoping Bao | nsf.gov |
| BRING-SynBio: Proteolytic Dosage Control of Protein Circuits to Modulate Intercellular Communications | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $300,000 | September 1, 2025 | August 31, 2027 | Xiaojing Gao | nsf.gov |
| BRING-SynBio: Dynamic cooperative binders for endogenously gated cellular control | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $300,000 | October 1, 2025 | September 30, 2027 | Bryan Dickinson | nsf.gov |
| BRING-SynBio: Erythritol-Driven and Spatiotemporal-Controlled Probiotics for Precise Delivery of Checkpoint-Blocking Nanobodies | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $300,000 | September 1, 2025 | August 31, 2029 | Qing Sun | nsf.gov |
| BRING-SynBio: Deciphering and directing lactylation epigenetics to control macrophage immune cell phenotype | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2025 | $300,000 | September 1, 2025 | August 31, 2027 | Catherine Fromen | nsf.gov |
| EAGER: Magnetothermal Control of Cell Fates and Function | NSF | Division of Molecular and Cellular Biosciences | 2022 | $299,999 | July 1, 2022 | June 30, 2024 | Christopher H Contag | nsf.gov |
| CAREER: Develop PROTAC-CID, a Novel Small Molecule Inducible Platform for Controllable Gene Expression in Mammalian Cells | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $286,360 | June 1, 2024 | June 30, 2027 | Xue Gao | nsf.gov |
| Collaborative Research: Synthetic acetyl-CoA-responsive metabolons for enhanced biosynthesis in yeast | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2026 | $282,710 | September 1, 2026 | August 31, 2029 | Nancy A Da Silva | nsf.gov |
| Collaborative Research: Synthetic acetyl-CoA-responsive metabolons for enhanced biosynthesis in yeast | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2026 | $281,224 | September 1, 2026 | August 31, 2029 | Wilfred Chen | nsf.gov |
| Collaborative Research: Quantitative analysis and modeling to determine the role of lipids in lymphatic permeability | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $265,151 | August 1, 2024 | July 31, 2027 | Stacey Finley | nsf.gov |
| Collaborative Research: Synthetic methane fixation cascades based on engineered membrane vesicles for biofuel cell applications | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2022 | $263,126 | September 1, 2022 | September 30, 2026 | Wilfred Chen | nsf.gov |
| Collaborative Research: Expanding the substrate range of Clostridium thermocellum to improve understanding of its metabolism | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $219,985 | December 15, 2023 | November 30, 2026 | Daniel Amador-Noguez | nsf.gov |
| CAREER: Develop PROTAC-CID, a Novel Small Molecule Inducible Platform for Controllable Gene Expression in Mammalian Cells | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2022 | $215,711 | July 1, 2022 | September 30, 2024 | Xue Gao | nsf.gov |
| ERI: Controlling Non-Specific Peptide Degradation in Hydrogels | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2022 | $207,000 | April 1, 2022 | March 31, 2025 | Eugene T Pashuck | nsf.gov |
| ERI: Multi-Activity Proteins for Improved Carbohydrate Deconstruction | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2022 | $200,000 | April 1, 2022 | March 31, 2026 | Renaud Berlemont | nsf.gov |
| ERI: Development of Non-native Sigma Factors for Metabolic Engineering | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2022 | $200,000 | June 1, 2022 | May 31, 2025 | Jason T Boock | nsf.gov |
| EAGER: Developing Biological drones for attacking targeted bacteria | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2022 | $200,000 | October 1, 2022 | September 30, 2025 | Christie A Peebles | nsf.gov |
| Collaborative Research: Investigating the role and interplay of microenvironment, manufacturing, and metabolism on MSC production of extracellular vesicles | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $200,000 | June 15, 2023 | May 31, 2027 | Donald R Griffin | nsf.gov |
| ERI: Integrating Non-Viral CRISPR Gene Activation and Deep Learning for Biomanufacturing Precision Stem Cell Products | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $200,000 | September 1, 2024 | August 31, 2027 | Tomas Gonzalez-Fernandez | nsf.gov |
| ERI: Modeling Bacterial Microcompartment Assembly Using a Data-Driven Multiscale Framework | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2022 | $199,998 | May 1, 2022 | April 30, 2025 | Alexander J Pak | nsf.gov |
| EAGER: Unveiling the transport mechanism of biosynthetic curcumin in engineered Escherichia coli | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2024 | $185,706 | September 1, 2024 | February 28, 2026 | Jixun Zhan | nsf.gov |
| Multiplex Next Generation Sequencing of Glycans and Nucleic Acids for Accelerating the Development of Cell Factories and Bioprocesses for Glycoprotein Biomanufacturing | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2024 | $159,541 | July 15, 2024 | March 31, 2026 | Nathan E Lewis | nsf.gov |
| Collaborative Research: Cell-free glycoprotein synthesis technology for point-of-care vaccine biomanufacturing | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2023 | $128,816 | March 1, 2023 | April 30, 2026 | Michael Jewett | nsf.gov |
| Conference: Biochemical and Molecular Engineering XXIII | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2024 | $99,950 | July 1, 2024 | December 31, 2024 | Michelle A O'Malley | nsf.gov |
| Conference: How SynBio can realistically impact crop improvement and agriculture | NSF | Division of Molecular and Cellular Biosciences | 2025 | $98,467 | January 1, 2025 | December 31, 2025 | Catalin Voiniciuc | nsf.gov |
| Collaborative Research: Investigating the role and interplay of microenvironment, manufacturing, and metabolism on MSC production of extracellular vesicles | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2023 | $86,662 | June 15, 2023 | May 31, 2027 | Sudhir K Khetan | nsf.gov |
| CAREER: Using Microbial Bioproduction Platform to Elucidate Phytochemical Biosynthesis - Strigolactone as An Example | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2022 | $86,154 | September 1, 2022 | March 31, 2024 | Yanran Li | nsf.gov |
| Workshop to Identify Convergent Nanotechnology Approaches for Precision Delivery of Active Agents in Plants | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2022 | $59,046 | August 1, 2022 | July 31, 2025 | Gregory V Lowry | nsf.gov |
| Conference: Facilitating Advanced Tissue Manufacturing | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2023 | $55,619 | March 15, 2023 | December 31, 2024 | Thomas Bollenbach | nsf.gov |
| Collaborative Research: Protein engineering and processing of plant viral templates for controlled nanoparticle synthesis | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $51,974 | January 15, 2024 | August 31, 2026 | Shohreh Hemmati | nsf.gov |
| Conference: An International Conference on Engineering Synthetic Cells and Organelles | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2023 | $50,000 | April 1, 2023 | March 31, 2024 | Kate Adamala | nsf.gov |
| 17th International Water Association World Conference on Anaerobic Digestion: Biogas and Beyond: Expanding Applications of Anaerobic Biotechnologies in a Circular Economy | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2022 | $49,975 | July 15, 2022 | June 30, 2023 | Lutgarde M Raskin | nsf.gov |
| Conference: Summer Biomechanics, Bioengineering, and Biotransport Conference (SB3C 2023); Vail, Colorado; 4-8 June 2023 | NSF | Division of Civil, Mechanical, and Manufacturing Innovation | 2023 | $49,433 | June 1, 2023 | May 31, 2024 | Stavros Thomopoulos | nsf.gov |
| Conference: Rapidly Addressing Gaps and Solutions in AI Education for Bioprocessing and Smart Manufacturing in Biotech (RAGSAB) | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2024 | $48,420 | September 15, 2024 | February 28, 2025 | Gabriel Levesque Tremblay | nsf.gov |
| Participant Support for the Eighth Triennial Conference on Foundations of Molecular Modeling and Simulation (FOMMS 2022) | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2022 | $48,375 | July 1, 2022 | June 30, 2023 | Jeffrey R Errington | nsf.gov |
| Conference: 2024 International Conference on Microbiome Engineering | NSF | Division of Molecular and Cellular Biosciences | 2024 | $47,525 | August 1, 2024 | July 31, 2025 | Evan Flach | nsf.gov |
| Students, Diversity Events, and a Systems Workshop at the 2022 Summer Biomechanics, Bioengineering, and Biotransport Conference (SB3C); Cambridge, Maryland; 20-23 June 2022 | NSF | Division of Civil, Mechanical, and Manufacturing Innovation | 2022 | $45,083 | June 1, 2022 | May 31, 2024 | Alisa M Clyne | nsf.gov |
| Conference: International Conference on Epigenetics & Bioengineering | NSF | Division of Molecular and Cellular Biosciences | 2024 | $33,400 | July 15, 2024 | December 31, 2024 | Evan Flach | nsf.gov |
| Conference: 12th International Conference on Biomolecular Engineering | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2023 | $29,805 | February 15, 2023 | January 31, 2024 | Evan Flach | nsf.gov |
| Conference: 2026 International Conference on Microbiome Engineering | NSF | Cell Development & Physiology | 2026 | $29,340 | August 15, 2026 | January 31, 2027 | Evan Flach | nsf.gov |
| Collaborative Research: Protein engineering and processing of plant viral templates for controlled nanoparticle synthesis | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2022 | $27,000 | October 1, 2021 | February 28, 2025 | Kevin Solomon | nsf.gov |
| CAREER: Degron-based substrates: A novel toolkit for biosensing and targeted inhibition | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2024 | $26,320 | October 1, 2023 | May 31, 2025 | Adam Melvin | nsf.gov |
| Collaborative Research: Mechanisms of Catalytic Enhancement of Immobilized Lipases by Tunable Polymer Materials | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2025 | $24,118 | October 1, 2024 | October 31, 2025 | Jim Pfaendtner | nsf.gov |
| 6th International Conference on Plant Synthetic Biology, Bioengineering and Biotechnology, Fort Lauderdale (FL), December 9-11, 2022 | NSF | Division Of Integrative Organismal Systems | 2023 | $23,295 | December 15, 2022 | November 30, 2023 | Kelsey Kettelhut | nsf.gov |
| Conference: Participant Support for the 2023 Biomedical Engineering Society - Cellular and Molecular Bioengineering Conference; Palm Springs, California; 2-6 January 2023 | NSF | Division of Civil, Mechanical, and Manufacturing Innovation | 2023 | $19,800 | December 1, 2022 | November 30, 2023 | Jianping Fu | nsf.gov |
| Travel: Symposium on Science and Technology Driving the Bioeconomy 2024 | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2024 | $19,000 | June 1, 2024 | May 31, 2026 | Christopher M Saffron | nsf.gov |
| Travel: Symposium on Science and Technology Driving the Bioeconomy 2023 | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2023 | $18,000 | June 1, 2023 | January 31, 2024 | Christopher M Saffron | nsf.gov |
| Conference: 2026 International Mammalian Synthetic Biology Workshop (mSBW) | NSF | Chemical, Bioengineering, Environmental, & Transport Systems | 2026 | $16,500 | August 1, 2026 | July 31, 2027 | Tara L Deans | nsf.gov |
| Conference: 2023 Mammalian Synthetic Biology Workshop | NSF | Division of Chemical, Bioengineering, Environmental, and Transport Systems | 2023 | $15,000 | August 1, 2023 | July 31, 2024 | Evan Flach | nsf.gov |
Organizations
Funding by fiscal year
| Fiscal year | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|
| 2026 | 0 | $0 | 19 | $7,627,978 |
| 2025 | 0 | $0 | 48 | $14,477,246 |
| 2024 | 0 | $0 | 45 | $14,352,166 |
| 2023 | 0 | $0 | 48 | $15,436,487 |
| 2022 | 0 | $0 | 40 | $15,929,607 |
Open federal funding opportunities
From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.
| Open opportunity | Number | Agency | Listing | Closes | Award ceiling | Why it matches |
|---|---|---|---|---|---|---|
| Unlocking Dataset Value for AI-Enabled Scientific Discovery (AI Datasets) | 26-512 | NSF | 47.041 | November 4, 2026 | Not listed | Same assistance listing 47.041 as 151 awards here |
| PFE: Research Initiation in Engineering Formation (PFE: RIEF) | 20-558 | NSF | 47.041 | November 10, 2026 | Not listed | Same assistance listing 47.041 as 151 awards here |
| National Science Foundation Translation to Practice (NSF TTP) | 25-540 | NSF | 47.041 | November 17, 2026 | $2 million | Same assistance listing 47.041 as 151 awards here |
| Training-based Workforce Development for Advanced Cyberinfrastructure | 23-520 | NSF | 47.041 | January 21, 2027 | $1 million | Same assistance listing 47.041 as 151 awards here |
| EPSCoR Research Infrastructure Improvement Program: Focused EPSCoR Collaborations (FEC) | 24-573 | NSF | 47.041 | January 26, 2027 | $1.5 million | Same assistance listing 47.041 as 151 awards here |
| GROWING CONVERGENCE RESEARCH (GCR) | 24-527 | NSF | 47.041 | February 8, 2027 | $3.6 million | Same assistance listing 47.041 as 151 awards here |
| Mid-scale Research Infrastructure-1 | 24-598 | NSF | 47.041 | February 8, 2027 | $20 million | Same assistance listing 47.041 as 151 awards here |
| EMERGING FRONTIERS IN RESEARCH AND INNOVATION (EFRI-2026/27): Wave-Based Computing ( EFRI-WBC) | 26-524 | NSF | 47.041 | February 11, 2027 | Not listed | Same assistance listing 47.041 as 151 awards here |
| Pathways to Enable Secure Open-Source Ecosystems (PESOSE) | 26-506 | NSF | 47.041 | March 2, 2027 | Not listed | Same assistance listing 47.041 as 151 awards here |
| NSF National Quantum Virtual Laboratory (NQVL) | 24-586 | NSF | 47.041 | April 6, 2027 | Not listed | Same assistance listing 47.041 as 151 awards here |
| EPSCoR Research Infrastructure Improvement (RII): EPSCoR Research Fellows | 24-528 | NSF | 47.041 | April 13, 2027 | Not listed | Same assistance listing 47.041 as 151 awards here |
| IUSE / Professional Formation of Engineers: Revolutionizing Engineering Departments (IUSE/PFE: RED) | 24-564 | NSF | 47.041 | April 13, 2027 | $2 million | Same assistance listing 47.041 as 151 awards here |
| Findable Accessible Interoperable Reusable Open Science (FAIROS) | 25-533 | NSF | 47.041 | April 14, 2027 | Not listed | Same assistance listing 47.041 as 151 awards here |
| EPSCoR Graduate Fellowship Program (EGFP) | 24-588 | NSF | 47.041 | June 1, 2027 | $3.2 million | Same assistance listing 47.041 as 151 awards here |
| Faculty Early Career Development Program (CAREER) | 22-586 | NSF | 47.041 | July 28, 2027 | Not listed | Same assistance listing 47.041 as 151 awards here |
| Research Experiences for Undergraduates (REU) | 23-601 | NSF | 47.041 | August 18, 2027 | $500,000 | Same assistance listing 47.041 as 151 awards here |
| Engineering Research Initiation (ERI) | 24-590 | NSF | 47.041 | September 16, 2027 | Not listed | Same assistance listing 47.041 as 151 awards here |
| Research Experiences for Teachers (RET) in Engineering and Computer Science | 24-503 | NSF | 47.041 | October 13, 2027 | Not listed | Same assistance listing 47.041 as 151 awards here |
| Historically Black Colleges and Universities - Excellence in Research (HBCU - EiR) | 23-598 | NSF | 47.041 | October 19, 2027 | Not listed | Same assistance listing 47.041 as 151 awards here |
| Transport Phenomena (TP) | PD-26-366Y | NSF | 47.041 | August 20, 2076 | Not listed | Same assistance listing 47.041 as 151 awards here |
Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.