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Python AI assistant repositories on GitHub: 15 ranked by stars

15 public Python repositories tagged AI assistant are on GitHub, with 16,824 stars between them; 10 had a push in the last 30 days. The most starred: FlorianBruniaux/claude-code-ultimate-guide (6,154), gptme/gptme (4,448), GH05TCREW/pentestagent (3,180).

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Every repository, most starred first

RepositoryWhat it isStarsForksLicenseLast pushRead
FlorianBruniaux/claude-code-ultimate-guideThe most comprehensive Claude Code guide: agentic workflows, hooks, skills, MCP servers, quizzes, and production-ready templates. 430K+ lines.6,154808CC-BY-SA-4.0Oct 13Oct 14
gptme/gptmeYour agent in your terminal, equipped with local tools: writes code, uses the terminal, browses the web. Make your own persistent autonomous agent on top!4,448450MITOct 14Oct 14
GH05TCREW/pentestagentPentestAgent is an AI agent framework for black-box security testing, supporting bug bounty, red-team, and penetration testing workflows.3,180629MITOct 12Oct 14
LiCinCan/blender-ai-mcp-addonAI assistant and MCP server for Blender: visual chat, scene tools, multi-agent workflows. Works with OpenAI, ChatGPT, Claude, Gemini, Ollama, OpenCode. Blender AI addon and…969389MITOct 20Oct 21
utensils/mcp-nixosMCP-NixOS - Model Context Protocol Server for NixOS resources85447MITSep 5Oct 14
hashgraph-online/awesome-ai-pluginsA curated list of the best awesome AI plugins for AI assistants including Claude Code, OpenAI Codex / ChatGPT, Gemini, Antigravity, Pi / Oh My Pi, Grok, OpenCodek DSH, Kimi and…636654Apache-2.0Oct 14Oct 14
wiresage/mikrotik-mcpMCP server for Mikrotik30167MITOct 11Oct 14
jgouviergmail/LIA-AssistantSmart multi-agent conversational assistant with LangGraph orchestration, Human-in-the-Loop, enterprise-grade observability, and full i18n support (6 languages)7311Oct 13Oct 14
mukul975/mcp-windows-automationAI-Powered Windows Automation Server using Model Context Protocol (MCP) | Control Windows apps, automate tasks, and manage systems through natural language commands with Claude…5915MITJun 3Oct 14
baryhuang/mcp-headless-gmailA MCP (Model Context Protocol) server that provides get, send Gmails without local credential or token setup.5529MITMay 24, 2025Oct 14
trendsmcp-ai/Trends-MCPMCP server for live trend data. Query Google Search, YouTube, TikTok, Reddit, Amazon, Wikipedia, News sentiment, Web Traffic, App Downloads, Steam, npm and more. Works with…443MITAug 29Oct 14
Artem-Kornilov-pro/mcp-ai-assistantPersonal AI assistant powered by LLM and MCP servers. Control files, GitHub repositories, and Google Sheets through natural language — all from the terminal. 134 tools, async chat…201MITSep 5Oct 14
XAIHT/TlamatiniTlamatini is a self-hosted AI developer assistant for local or cloud LLMs: hybrid RAG (FAISS+BM25) over your codebase, a 100+ tool Multi-Turn engine, an 86-agent visual workflow…151MITOct 14Oct 14
bigsk1/jarvis-voicePersonal self-hosted AI assistant. Voice control, 200+ tools. Cloud or fully local with Ollama. UI, CLI, TUI. Deterministic (code-driven) orchestration!81Oct 12Oct 14
ellmos-ai/bachBACH v3.13.0-bluesky: local-first text-based OS for LLM agents with SQLite memory, 113+ handlers, 550+ tools, MCP servers, scheduler and multi-agent orchestration83MITOct 14Oct 14

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Every AI assistant repository

Read from GitHub by SpecStream between October 14, 2026 and October 21, 2026; each row shows the day its repository was read. Stars and pushes change every day, and the GitHub page is the current one. Forks and archived repositories are left out.