Data / Nonprofits / Virginia / Roanoke
Nonprofits in Roanoke, VA: 1,088 registered with the IRS
1,088 nonprofits are registered with the IRS in Roanoke, VA, 921 of them 501(c)(3) charities; the 340 that report revenue took in $5.54 billion. The largest by revenue: Carilion Medical Center ($2.32 billion), Delta Dental Plan of Virginia ($861.5 million), Carilion Services Inc ($514.3 million). Most common causes: religion-related (92), human services (83), education (75).
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The 500 largest by revenue
| Organization | Category | Type | Since | Revenue | Assets | Filing |
|---|---|---|---|---|---|---|
| Carilion Medical Center | Health care | 501(c)(3) | 1980 | $2.32 billion | $2.38 billion | 2025-09 |
| Delta Dental Plan of Virginia | Health care | 501(c)(4) | 1971 | $861.5 million | $207.7 million | 2024-12 |
| Carilion Services Inc | Health care | 501(c)(3) | 1982 | $514.3 million | $1.34 billion | 2025-09 |
| Carilion New River Valley Medical Center | Health care | 501(c)(3) | 1941 | $407.8 million | $579.6 million | 2025-09 |
| Carilion Giles Community Hospital | Health care | 501(c)(3) | 1952 | $136.6 million | $71.2 million | 2025-09 |
| Carilion Franklin Memorial Hospital | Health care | 501(c)(3) | 1956 | $114.9 million | $65.1 million | 2025-09 |
| Goodwill Industries of the Valley Works | Human services | 501(c)(3) | 2009 | $104.2 million | $47.5 million | 2024-12 |
| Carilion Rockbridge Community Hospital | Health care | 501(c)(3) | 1955 | $101.2 million | $100.4 million | 2025-09 |
| Richfield Living | Health care | 501(c)(3) | 1940 | $85.9 million | $434,323 | 2024-09 |
| Hollins University Corporation | Education | 501(c)(3) | 1925 | $77.4 million | $425.4 million | 2025-06 |
| Lutheran Family Services of Virginia Inc | Human services | 501(c)(3) | 2000 | $59.9 million | $22.5 million | 2025-06 |
| Friendship Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1989 | $45 million | $111.1 million | 2025-06 |
| Carilion Clinic | Health care | 501(c)(3) | 1982 | $42.3 million | $257.9 million | 2025-09 |
| Friendship Health and Rehab Center Inc | Health care | 501(c)(3) | 1973 | $32.9 million | $38.6 million | 2025-06 |
| Virginia Lutheran Homes Inc | 501(c)(3) | 1963 | $32.3 million | $112.2 million | 2025-12 | |
| Depaul Community Resources | 501(c)(3) | 2005 | $27.4 million | $13.2 million | 2025-06 | |
| Total Action Against Poverty in Roanoke Valley | Human services | 501(c)(3) | 1965 | $27.1 million | $18.4 million | 2025-06 |
| Carilion Tazewell Community Hospital | Health care | 501(c)(3) | 1968 | $27 million | $9.7 million | 2025-09 |
| Goodwill Industries of the Valleys Inc | Employment | 501(c)(3) | 1970 | $24 million | $76 million | 2024-12 |
| Good Samaritan Hospice Inc | Health care | 501(c)(3) | 1992 | $20.5 million | $19.7 million | 2025-12 |
| Our Lady of Hope Health Center Inc | 501(c)(3) | 1946 | $20.5 million | $22.3 million | 2025-06 | |
| Friendship Health and Rehab Center South Inc | Health care | 501(c)(3) | 2014 | $18.1 million | $25.6 million | 2025-06 |
| Our Lady of the Valley Inc | 501(c)(3) | 1946 | $16.6 million | $22.1 million | 2025-06 | |
| North Cross School | Education | 501(c)(3) | 1964 | $16.2 million | $25.3 million | 2025-06 |
| Carilion Clinic Foundation | Health care | 501(c)(3) | 1982 | $15.5 million | $85.3 million | 2025-09 |
| Young Mens Christian Association of Virginias Blue Ridge Inc | 501(c)(3) | 1937 | $14.9 million | $30.3 million | 2025-08 | |
| Our Lady of Peace Inc | Housing and shelter | 501(c)(3) | 1946 | $13.9 million | $17.7 million | 2025-06 |
| Kuumba Community Health & Wellness Center Inc | Health care | 501(c)(3) | 1999 | $13.6 million | $11.8 million | 2025-05 |
| Community Foundation Serving Western Virginia | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2000 | $13.3 million | $138.6 million | 2025-06 |
| Our Lady of Perpetual Help Health Center Inc | Human services | 501(c)(3) | 1946 | $12.8 million | $15.2 million | 2025-06 |
| Virginia Transformer Corp Health Care Benefits Trust | 501(c)(9) | 1995 | $12.8 million | $0 | 2024-12 | |
| Virginia Utility Protection Service Inc | Community improvement and capacity building | 501(c)(6) | 2006 | $11.3 million | $18.9 million | 2025-12 |
| Southeast Rural Community Assistance Project Inc | Public and societal benefit | 501(c)(3) | 1977 | $10.7 million | $12.1 million | 2025-09 |
| Marian Manor Inc | Human services | 501(c)(3) | 1984 | $8.5 million | $11 million | 2025-06 |
| Unified Human Services Transportation System Inc | Human services | 501(c)(3) | 1977 | $7.8 million | $6.4 million | 2025-09 |
| Council of Community Services | Human services | 501(c)(3) | 1964 | $7.4 million | $3.1 million | 2025-06 |
| Bradley Free Clinic of Roanoke Valley | 501(c)(3) | 1975 | $7.1 million | $11.4 million | 2025-06 | |
| Chesterbrook Residences Inc | Human services | 501(c)(3) | 2002 | $6.6 million | $17.6 million | 2024-12 |
| Friendship Apartment Village Corporation | Housing and shelter | 501(c)(3) | 1979 | $6.4 million | $30.2 million | 2025-06 |
| United Way of Virginias Blue Ridge | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1942 | $6.1 million | $7.5 million | 2025-06 |
| Rescue Mission of Roanoke Inc | Human services | 501(c)(3) | 1954 | $5.8 million | $11.2 million | 2024-12 |
| Habitat for Humanity in the Roanoke Valley Inc | 501(c)(3) | 1987 | $5.4 million | $12.8 million | 2025-06 | |
| Blue Ridge Public Television | Arts, culture and humanities | 501(c)(3) | 1966 | $5.3 million | $8.2 million | 2025-06 |
| Renewanation | Education | 501(c)(3) | 2009 | $5.1 million | $6.3 million | 2024-12 |
| Assisi Animal Clinics of Virginia Inc | Animal-related | 501(c)(3) | 2001 | $4.7 million | $6 million | 2025-12 |
| Faith Christian School | Education | 501(c)(3) | 1997 | $4.5 million | $6.4 million | 2025-06 |
| The Taubman Museum of Art | Arts, culture and humanities | 501(c)(3) | 1954 | $4.5 million | $73.7 million | 2025-06 |
| Eastwood Assisted Living Inc | Health care | 501(c)(3) | 1979 | $4.4 million | $2.4 million | 2025-06 |
| Disabled American Veterans | 501(c)(4) | 1946 | $4.4 million | $23.1 million | 2025-06 | |
| Roanoke Country Club Inc | 501(c)(7) | 1952 | $4.3 million | $4.3 million | 2024-12 | |
| Life Sciences Trainers & Educators | Health care | 501(c)(3) | 2006 | $4.3 million | $5.9 million | 2025-12 |
| Roanoke Valley Convention and Vis- Itors Bureau | 501(c)(6) | 1990 | $4.3 million | $3 million | 2025-06 | |
| Local Office On Aging Inc | Human services | 501(c)(3) | 1973 | $3.9 million | $5 million | 2025-09 |
| Western Virginia Foundation for the Arts and Sciences | Arts, culture and humanities | 501(c)(3) | 1979 | $3.7 million | $31.7 million | 2025-06 |
| Certified Medical Representatives Institute Inc | 501(c)(3) | 1970 | $3.2 million | $3.9 million | 2025-06 | |
| Local Environmental Agriculture Project Incorporated | Food, agriculture and nutrition | 501(c)(3) | 2013 | $3 million | $3.3 million | 2025-12 |
| Blue Ridge Behavioral Healthcare Inc | 501(c)(3) | 2007 | $3 million | $14.5 million | 2025-06 | |
| RBM Opco of Fincastle LLC | 501(c)(3) | 1993 | $2.8 million | $370,548 | 2005-12 | |
| National Pku Alliance Inc | Medical research | 501(c)(3) | 2009 | $2.7 million | $6.2 million | 2025-12 |
| Ronald McDonald House Charities of Southwest Virginia Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1985 | $2.6 million | $3.6 million | 2024-12 |
| Kissito Healthcare Inc | 501(c)(3) | 1993 | $2.6 million | $371,044 | 2005-12 | |
| Roanoke Area Ministries | 501(c)(3) | 1976 | $2.6 million | $2.4 million | 2024-12 | |
| Greater Roanoke Workforce Development Board | Human services | 501(c)(3) | 2006 | $2.5 million | $807,999 | 2025-06 |
| Girl Scouts of Virginia Skyline Council Inc | 501(c)(3) | 1945 | $2.4 million | $5.8 million | 2025-09 | |
| Virginia Western Community College Educational Founation Inc | Education | 501(c)(3) | 1981 | $2.4 million | $34.6 million | 2024-07 |
| Family Service of Roanoke Valley | Human services | 501(c)(3) | 1972 | $2.4 million | $2.5 million | 2025-06 |
| Boys & Girls Clubs of Southwest Virginia Inc | Youth development | 501(c)(3) | 1997 | $2.3 million | $2.5 million | 2024-12 |
| Saint Francis Service Dogs | Human services | 501(c)(3) | 1996 | $2.3 million | $6.2 million | 2026-05 |
| Jefferson Center Foundation LTD | Arts, culture and humanities | 501(c)(3) | 1989 | $2.3 million | $22.7 million | 2025-06 |
| Community School | Education | 501(c)(3) | 1971 | $2.3 million | $5.3 million | 2025-07 |
| Boy Scouts of America | 501(c)(3) | 1965 | $2.2 million | $2.9 million | 2024-12 | |
| Laborers International Union of North America | 501(c)(5) | 1966 | $2.2 million | $9.8 million | 2025-06 | |
| Brain Injury Services of Swva | Diseases, disorders and medical disciplines | 501(c)(3) | 2001 | $2.1 million | $2.5 million | 2025-06 |
| Legal Aid Society of Roanoke Valley Inc | 501(c)(3) | 1968 | $2.1 million | $1.9 million | 2025-06 | |
| Western Virginia Emergency Medical Services Council Inc | Health care | 501(c)(3) | 1976 | $2 million | $2.7 million | 2025-06 |
| Delta Dental of Virginia Foundation Inc | Health care | 501(c)(3) | 2012 | $2 million | $521,140 | 2024-12 |
| Scott Hill Incorporated | Housing and shelter | 501(c)(3) | 1981 | $2 million | $2.3 million | 2025-01 |
| The Russell House Inc | Housing and shelter | 501(c)(3) | 1979 | $1.9 million | $4.6 million | 2025-12 |
| Restoration Housing | Housing and shelter | 501(c)(3) | 2015 | $1.9 million | $5.1 million | 2025-12 |
| Virginia Crisis Intervention Team Coalition | Mental health and crisis intervention | 501(c)(3) | 2022 | $1.9 million | $1.9 million | 2025-06 |
| Friendship Outpatient & Wellnessservices Inc | Health care | 501(c)(3) | 2007 | $1.9 million | $551,550 | 2025-06 |
| Presbyterian Community Center Inc | Human services | 501(c)(3) | 1992 | $1.9 million | $6.8 million | 2025-06 |
| Downtown Roanoke Incorporated | 501(c)(6) | 1984 | $1.8 million | $1.1 million | 2025-06 | |
| Life Ring Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2012 | $1.8 million | $1.9 million | 2024-12 |
| Virginia Harm Reduction Coalition | Mental health and crisis intervention | 501(c)(3) | 2018 | $1.8 million | $508,171 | 2025-06 |
| Free Foundation for Rehabilitation Equipment & Endowment | Human services | 501(c)(3) | 1999 | $1.7 million | $671,343 | 2025-12 |
| Va United Futbol Club | Recreation and sports | 501(c)(3) | 2025 | $1.7 million | $262,572 | 2025-06 |
| Child Health Investment Partnership | 501(c)(3) | 1992 | $1.6 million | $3.9 million | 2025-06 | |
| The Shenandoah Club | 501(c)(7) | 1929 | $1.6 million | $737,706 | 2025-01 | |
| Community High School of the Roanoke Valley | Education | 501(c)(3) | 2005 | $1.6 million | $852,671 | 2025-07 |
| Blue Ridge Zoological Society of Virginia Inc | Animal-related | 501(c)(3) | 1976 | $1.6 million | $2 million | 2025-06 |
| Better Business Bureau of Western Virginia Inc | 501(c)(6) | 1940 | $1.6 million | $1.6 million | 2024-12 | |
| Roanoke Regional Partnership | 501(c)(6) | 1984 | $1.5 million | $2 million | 2025-06 | |
| Roanoke Symphony Orchestra | Arts, culture and humanities | 501(c)(3) | 1956 | $1.5 million | $1.8 million | 2025-06 |
| Edinburgh Square Foundation | Housing and shelter | 501(c)(3) | 1988 | $1.5 million | $3.3 million | 2025-09 |
| Virginia Community Action Reentry System | Crime and legal-related | 501(c)(3) | 1982 | $1.4 million | $372,833 | 2025-06 |
| Culpepper Garden I Incorporated | Housing and shelter | 501(c)(3) | 1972 | $1.4 million | $23 million | 2025-06 |
| Childrens Trust Foundation Roanoke Valley Inc | Crime and legal-related | 501(c)(3) | 1979 | $1.4 million | $689,162 | 2025-06 |
| Project Discovery Inc | Education | 501(c)(3) | 1986 | $1.4 million | $118,859 | 2025-06 |
| Veterans Community Development Corporation Inc | Human services | 501(c)(3) | 2014 | $1.4 million | $1.5 million | 2024-12 |
| Marywood Inc | 501(c)(3) | 1981 | $1.4 million | $2.7 million | 2024-12 | |
| Cardinal Productions | Public and societal benefit | 501(c)(3) | 2022 | $1.4 million | $1.3 million | 2024-12 |
| Harvey W Peters Virginia Holding Corporation | Community improvement and capacity building | 501(c)(2) | 2003 | $1.3 million | $18.8 million | 2025-06 |
| Blue Ridge Independent Living Center Inc | Human services | 501(c)(3) | 1989 | $1.3 million | $593,877 | 2025-09 |
| Sullivan House Inc | 501(c)(3) | 1946 | $1.3 million | $5.9 million | 2024-12 | |
| Blue Ridge Womens Center Inc | Health care | 501(c)(3) | 1984 | $1.3 million | $2.9 million | 2024-12 |
| I C Corporation | 501(c)(3) | 1983 | $1.2 million | $3.6 million | 2025-06 | |
| Virginia Lutheran Homes Home Care Inc | 501(c)(3) | 1988 | $1.2 million | $226,599 | 2025-12 | |
| Roanoke Valley Spca | Animal-related | 501(c)(3) | 1958 | $1.2 million | $5.6 million | 2025-06 |
| Grandin Theatre Foundation Inc | Arts, culture and humanities | 501(c)(3) | 2002 | $1.2 million | $2.8 million | 2024-12 |
| Mill Mountain Playhouse Co | Arts, culture and humanities | 501(c)(3) | 1967 | $1.2 million | $1.2 million | 2025-12 |
| Virginia Museum of Transportation Inc | Arts, culture and humanities | 501(c)(3) | 1977 | $1.2 million | $6.3 million | 2025-06 |
| Lifeline Foundation | 501(c)(3) | 1992 | $1.2 million | $4.4 million | 2024-12 | |
| Straight Street Roanoke Valley Inc | Youth development | 501(c)(3) | 1995 | $1.2 million | $2.1 million | 2024-12 |
| Roanoke Valley Speech and Hearing Center Inc | Health care | 501(c)(3) | 1962 | $1.2 million | $575,523 | 2024-06 |
| Renovation Alliance | Housing and shelter | 501(c)(3) | 2000 | $1.2 million | $119,401 | 2026-06 |
| New Vista Montessori School | Education | 501(c)(3) | 2002 | $1.1 million | $324,488 | 2025-06 |
| Roanoke Valley Association of Realtors | 501(c)(6) | 1972 | $1.1 million | $3.8 million | 2024-12 | |
| International Swim Coaches Association | Recreation and sports | 501(c)(3) | 2014 | $1.1 million | $1.1 million | 2025-12 |
| Roanoke Cultural Endowment | Arts, culture and humanities | 501(c)(3) | 2015 | $1.1 million | $8.5 million | 2025-12 |
| Mountain View Humane | Animal-related | 501(c)(3) | 2009 | $1.1 million | $964,544 | 2025-06 |
| Ward Transitional Services Inc | Human services | 501(c)(3) | 2016 | $1 million | $211,582 | 2024-12 |
| Symbiosis Coalition | Environment | 501(c)(4) | 2026 | $973,567 | $828,125 | 2024-12 |
| Benevolent & Protective Order of Elks of the USA | 501(c)(8) | 1951 | $970,192 | $980,187 | 2026-03 | |
| Five Points Music Foundation | Arts, culture and humanities | 501(c)(3) | 2017 | $939,918 | $228,836 | 2024-12 |
| My Fathers House International Inc | International, foreign affairs and national security | 501(c)(3) | 2005 | $938,222 | $195,681 | 2025-12 |
| Answering the Call Inc | International, foreign affairs and national security | 501(c)(3) | 2002 | $885,134 | $1 million | 2024-12 |
| Kovar Corporation | Human services | 501(c)(3) | 1983 | $868,070 | $2.8 million | 2025-06 |
| Chamber of Commerce of Roanoke | 501(c)(6) | 1937 | $856,212 | $1.4 million | 2024-12 | |
| Kings Christian Academy Roanoke Inc | Education | 501(c)(3) | 2020 | $812,038 | $15,338 | 2025-06 |
| Roanoke Outside | Recreation and sports | 501(c)(3) | 2013 | $779,110 | $637,751 | 2025-06 |
| Southwest Virginia Wildlife Center of Roanoke Inc | Animal-related | 501(c)(3) | 2016 | $730,756 | $653,297 | 2025-12 |
| Science Museum of Western Virginia | Arts, culture and humanities | 501(c)(3) | 1970 | $693,769 | $344,158 | 2023-06 |
| Ridgely Senior Care Corp | Human services | 501(c)(3) | 2020 | $690,671 | $16.1 million | 2024-12 |
| Non-Union Retirees of Roanoke Gas Co Voluntary Empls Beneficiary PLN | 501(c)(9) | 1994 | $668,805 | $12.7 million | 2024-12 | |
| West End Center Inc | Education | 501(c)(3) | 1984 | $655,934 | $2 million | 2025-06 |
| FV Cemetery Company Inc | 501(c)(13) | 1908 | $645,649 | $2 million | 2026-04 | |
| A Tree Planted Inc | Mental health and crisis intervention | 501(c)(3) | 2018 | $627,121 | $77,318 | 2025-12 |
| Eastern Dominican Christian Mission Inc | Religion-related | 501(c)(3) | 2020 | $625,235 | $214,477 | 2025-12 |
| USA Softball of Virginia Inc | Recreation and sports | 501(c)(3) | 2016 | $621,497 | $16,278 | 2024-12 |
| Blue Ridge Fellows Program Inc | 501(c)(3) | 2015 | $616,933 | $636,327 | 2025-06 | |
| Friends of the Blue Ridge Parkway Inc | Environment | 501(c)(3) | 1989 | $597,602 | $415,710 | 2026-06 |
| Saint Basil Academy Trust | 501(c)(3) | 2017 | $592,102 | $8.5 million | 2024-12 | |
| Valley Youth Hockey Association Inc | 501(c)(3) | 1990 | $588,471 | $233,929 | 2025-06 | |
| Warrior Expeditions | Human services | 501(c)(3) | 2015 | $586,157 | $341,589 | 2025-09 |
| Next Revolution Volleyball Corp | Recreation and sports | 501(c)(3) | 2017 | $577,558 | $131,289 | 2025-06 |
| International Alliance for Mercy Inc | International, foreign affairs and national security | 501(c)(3) | 2014 | $554,084 | $641,568 | 2025-12 |
| Least of These Ministry | Religion-related | 501(c)(3) | 2018 | $551,745 | $517,544 | 2025-12 |
| Elm Manor Homes | 501(c)(3) | 1983 | $483,269 | $909,531 | 2025-10 | |
| Roanoke Ballet Theatre Inc | Arts, culture and humanities | 501(c)(3) | 1980 | $474,019 | $179,249 | 2024-12 |
| Cca Marlins | 501(c)(3) | 2021 | $457,321 | $254,301 | 2025-06 | |
| Land Savers United | Environment | 501(c)(3) | 1997 | $448,093 | $1.8 million | 2025-06 |
| Huddle Up Moms | Human services | 501(c)(3) | 2021 | $444,990 | $274,178 | 2025-09 |
| Apple Ridge Farm Incorporated | 501(c)(3) | 1989 | $439,755 | $2 million | 2025-12 | |
| Prevention Council of Roanoke County | 501(c)(3) | 2008 | $420,524 | $160,640 | 2025-09 | |
| Christ Together Inc | Religion-related | 501(c)(3) | 2010 | $410,786 | $153,687 | 2024-12 |
| Scottish Rite Foudation of Virginia | Education | 501(c)(3) | 2022 | $406,386 | $2.4 million | 2025-08 |
| Kids Soar | Human services | 501(c)(3) | 2003 | $388,901 | $44,844 | 2023-06 |
| Shenandoah Valley Lutheran Housing Incorporated | 501(c)(3) | 1983 | $388,353 | $530,189 | 2025-12 | |
| Family Promise of Greater Roanoke Inc | Human services | 501(c)(3) | 1997 | $372,028 | $815,519 | 2024-12 |
| Blue Ridge Literacy | Education | 501(c)(3) | 2004 | $366,374 | $526,654 | 2025-06 |
| Blue Ridge Partnership for Health Science Careers of Virginia | Science and technology | 501(c)(4) | 2024 | $353,887 | $363,588 | 2025-12 |
| Opera Roanoke | Arts, culture and humanities | 501(c)(3) | 1977 | $346,545 | $641,374 | 2025-06 |
| Friendship House Roanoke Inc | Human services | 501(c)(3) | 2019 | $335,397 | $711,471 | 2024-12 |
| Sexual Assault Response and Awareness Inc | Mental health and crisis intervention | 501(c)(3) | 2011 | $333,429 | $383,507 | 2025-06 |
| On Our Own of Roanoke Valley Inc | Arts, culture and humanities | 501(c)(3) | 1995 | $328,995 | $65,615 | 2025-12 |
| Southwest Virginia Ballet Company | Arts, culture and humanities | 501(c)(3) | 1993 | $312,109 | $334,289 | 2024-06 |
| Scott Robertson Memorial Junior Golf Academy | Recreation and sports | 501(c)(3) | 2004 | $311,292 | $949,902 | 2024-12 |
| Virginia Association for Biological Farming | Food, agriculture and nutrition | 501(c)(3) | 2009 | $310,509 | $85,788 | 2025-03 |
| Center in the Square Endowment Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1996 | $305,895 | $3.8 million | 2025-06 |
| Pathfinders for Greenways | Environment | 501(c)(3) | 1998 | $305,024 | $623,672 | 2025-12 |
| Roanoke Valley Swimming Inc | Recreation and sports | 501(c)(3) | 1988 | $299,625 | $827,700 | 2025-08 |
| Knights Booster Foundation | Education | 501(c)(3) | 2005 | $293,096 | $299,539 | 2025-06 |
| Community Housing Corporation | Housing and shelter | 501(c)(3) | 2020 | $286,961 | $1.3 million | 2024-12 |
| Miss Virginia Opportunity Inc | Education | 501(c)(4) | 2026 | $282,778 | $116,358 | 2025-09 |
| Historical Society of Western Virginia | Arts, culture and humanities | 501(c)(3) | 1964 | $281,044 | $2.9 million | 2025-06 |
| The Roanoke Jewish Federation | Religion-related | 501(c)(3) | 2012 | $278,093 | $2.9 million | 2025-12 |
| Valley Afc Inc | Recreation and sports | 501(c)(3) | 1997 | $276,307 | $746,700 | 2024-12 |
| Operation Walk - Women Orthopaedist Global Outreach | Health care | 501(c)(3) | 2010 | $272,267 | $909,093 | 2024-12 |
| Roanoke Valley Youth Soccer Club Inc | Recreation and sports | 501(c)(3) | 1987 | $267,404 | $1.4 million | 2025-06 |
| Market Building Foundation Inc | Community improvement and capacity building | 501(c)(3) | 2020 | $264,417 | $6.6 million | 2024-12 |
| India Heritage Society | 501(c)(3) | 1989 | $256,678 | $939,737 | 2025-12 | |
| International Association of Fire Fighters | 501(c)(5) | 1964 | $249,103 | $500,370 | 2025-12 | |
| Community Youth Program at St Johns Inc | Education | 501(c)(3) | 1998 | $243,355 | $328,161 | 2025-06 |
| Roanoke Juniors Volleyball Association Inc | Recreation and sports | 501(c)(7) | 2004 | $242,033 | $4,110 | 2025-12 |
| Roanoke Childrens Theatre Inc | Arts, culture and humanities | 501(c)(3) | 2009 | $235,675 | $69,510 | 2024-08 |
| Compress and Shock Foundation | Public safety, disaster preparedness and relief | 501(c)(3) | 2018 | $234,099 | $119,236 | 2025-12 |
| Junior Achievement of Southwest Virginia Inc | International, foreign affairs and national security | 501(c)(3) | 1994 | $231,603 | $424,912 | 2025-06 |
| Roanoke Higher Education Center Foundation | Education | 501(c)(3) | 1999 | $216,633 | $449,942 | 2025-06 |
| Humble Hustle Company Inc | Mental health and crisis intervention | 501(c)(3) | 2016 | $214,309 | $65,259 | 2024-12 |
| Veterans of Foreign Wars of the United States Dept of Virginia | 501(c)(19) | 1965 | $214,137 | $792,928 | 2024-12 | |
| Four Truths Recovery | 501(c)(3) | 2024 | $213,568 | $54,218 | 2025-06 | |
| Virginia Egg Council Inc | 501(c)(6) | 1986 | $211,429 | $182,013 | 2025-06 | |
| Junior League of Roanoke Va Inc | Community improvement and capacity building | 501(c)(3) | 1943 | $209,333 | $2.6 million | 2025-05 |
| Down By Downtown Music Inc | 501(c)(3) | 2016 | $209,065 | $41,545 | 2025-12 | |
| Deaf & Hard of Hearing Services Center Inc | Human services | 501(c)(3) | 1997 | $208,988 | $319,906 | 2024-12 |
| Patrick Henry School Boosters Assoc | 501(c)(3) | 1963 | $206,708 | $155,888 | 2024-06 | |
| Hidden Valley High School Athletic Booster Club Inc | Education | 501(c)(3) | 2025 | $205,575 | $0 | 2025-06 |
| Vinton Chamber of Commerce Inc | 501(c)(6) | 1958 | $205,221 | $34,063 | 2024-12 | |
| Mish Moves Dance Company Inc | Arts, culture and humanities | 501(c)(3) | 2020 | $198,243 | $198,243 | 2024-12 |
| Clean Valley Council Inc | Environment | 501(c)(3) | 1978 | $194,336 | $219,180 | 2025-06 |
| Teachers of Promise Foundation | Education | 501(c)(3) | 2011 | $190,205 | $164,083 | 2025-12 |
| Shield Chaplaincy Inc | Mental health and crisis intervention | 501(c)(3) | 2022 | $189,129 | $30,029 | 2025-12 |
| Williamson Road Area Business Association Inc | 501(c)(6) | 1989 | $182,551 | $88,288 | 2025-12 | |
| Communication Workers of America | 501(c)(5) | 1950 | $174,152 | $787,737 | 2025-09 | |
| Harrison Museum of African American Culture | Arts, culture and humanities | 501(c)(3) | 1993 | $173,305 | $449,124 | 2025-06 |
| Star City Canine Club Inc | Animal-related | 501(c)(4) | 2016 | $162,254 | $246,975 | 2024-12 |
| Floyd Ward Dance Ensembles Inc | Recreation and sports | 501(c)(3) | 2018 | $161,531 | $82,788 | 2025-07 |
| Roanoke Public Library Foundation | 501(c)(3) | 1954 | $158,037 | $2 million | 2024-12 | |
| Norfolk & Western Historical Society Inc | 501(c)(3) | 1990 | $157,299 | $847,475 | 2025-12 | |
| Keystone Community Center Inc | Religion-related | 501(c)(3) | 2018 | $156,720 | $266,523 | 2025-12 |
| Roanoke Asylum-Seekers Support Network | Human services | 501(c)(3) | 2020 | $155,561 | $60,457 | 2026-02 |
| Associaton of United States Night Vision Manufacturers | 501(c)(6) | 1980 | $150,750 | $118,649 | 2024-12 | |
| American Federation of Government Employees | 501(c)(5) | 1940 | $150,465 | $213,249 | 2025-12 | |
| First Fridays at Five Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1991 | $148,555 | $39,499 | 2024-12 |
| New Hope Korean Presbyterian Church | Religion-related | 501(c)(3) | 2017 | $148,540 | $230,829 | 2024-12 |
| Amvets | 501(c)(19) | 1954 | $141,369 | $836,890 | 2024-12 | |
| Kiwanis Foundation of Roanoke | Community improvement and capacity building | 501(c)(3) | 1957 | $140,212 | $1.7 million | 2025-10 |
| Flames Way Inc | Public and societal benefit | 501(c)(3) | 2023 | $138,065 | $21,333 | 2024-12 |
| The Bridge Institute Inc | Human services | 501(c)(3) | 2006 | $135,859 | $11,650 | 2025-06 |
| Roanoke Refugee Partnership | Civil rights, social action and advocacy | 501(c)(3) | 2017 | $133,402 | $210,599 | 2025-12 |
| Orchard Hills Achievement Center Inc | Human services | 501(c)(3) | 2015 | $130,302 | $42,605 | 2024-12 |
| Barnabas Stables Inc | Recreation and sports | 501(c)(3) | 2023 | $129,715 | $340,607 | 2025-12 |
| Mill Mountain Garden Club Inc | Education | 501(c)(3) | 2008 | $128,504 | $263,337 | 2026-05 |
| Roanoke County Public Schools Education Foundation Inc | Education | 501(c)(3) | 1992 | $127,885 | $770,367 | 2025-06 |
| North Roanoke Recreation Club | Recreation and sports | 501(c)(3) | 2026 | $126,901 | $41,450 | 2025-12 |
| Spring Run Swim Club Inc | 501(c)(7) | 1968 | $123,958 | $104,517 | 2024-12 | |
| Virginia Association for Health Pe and Dance | Youth development | 501(c)(3) | 2018 | $122,498 | $823,226 | 2026-05 |
| Shriners International | 501(c)(10) | 1949 | $120,394 | $231,993 | 2024-12 | |
| Roanoke Assembly | 501(c)(7) | 1963 | $119,680 | $123,065 | 2025-12 | |
| Elbyrne G Gill Eye and Ear Foundation | 501(c)(3) | 1957 | $119,148 | $1.2 million | 2025-06 | |
| Ancient & Accepted Scottish Rite of Free Masonry Southern Jurisdiction | Arts, culture and humanities | 501(c)(10) | 1940 | $118,792 | $1.2 million | 2024-12 |
| Hope Center 11TH St NW | Community improvement and capacity building | 501(c)(3) | 2024 | $117,719 | $13,783 | 2025-12 |
| Omnah Foundation | Animal-related | 501(c)(3) | 2021 | $117,020 | $41,267 | 2025-12 |
| Studio School | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2000 | $116,417 | $38,586 | 2024-12 |
| Virginia Cavaliers Baseball | 501(c)(3) | 2023 | $115,281 | $33,602 | 2025-12 | |
| Deeper Waters Ministry | Human services | 501(c)(3) | 2018 | $110,260 | $47,467 | 2025-12 |
| Trust for the Benefit of Union Retirees of Roanoke Gas Company | 501(c)(9) | 1994 | $108,918 | $1.9 million | 2024-12 | |
| Roanoke Valley Volleyball Incorporated | Recreation and sports | 501(c)(7) | 2022 | $108,773 | $121,519 | 2025-11 |
| National Association of Letter Carriers | 501(c)(5) | 1944 | $107,217 | $385,051 | 2025-12 | |
| Northwest Neighborhood Enviromental Organization Incorporated | Community improvement and capacity building | 501(c)(3) | 1989 | $106,545 | $471,416 | 2025-12 |
| Roanoke County Volunteer Fire Department 3 Cave Spring | Public safety, disaster preparedness and relief | 501(c)(3) | 2025 | $106,303 | $394,673 | 2024-12 |
| Fame Roanoke Booster Club | Recreation and sports | 501(c)(3) | 2021 | $104,415 | $21,402 | 2026-04 |
| Showtimers of Roanoke Valley Inc Showtimers | Arts, culture and humanities | 501(c)(3) | 2014 | $104,292 | $302,970 | 2024-12 |
| International Association of Lions | 501(c)(4) | 1969 | $104,190 | $654,628 | 2025-06 | |
| Vaks I LTD | 501(c)(3) | 1991 | $103,800 | $2,196 | 2024-12 | |
| Wild Way | Youth development | 501(c)(3) | 2021 | $103,267 | $53,630 | 2025-06 |
| Cultural Arts for Excellence | Youth development | 501(c)(3) | 2011 | $102,905 | $67,336 | 2022-12 |
| Roanoke Chapter National Railway Historical Society | 501(c)(3) | 1968 | $100,491 | $7.9 million | 2025-12 | |
| Izaak Walton League of America Inc | 501(c)(3) | 1985 | $98,023 | $525,777 | 2025-12 | |
| Tudor House | Mental health and crisis intervention | 501(c)(3) | 2020 | $97,937 | $133,162 | 2024-12 |
| Roanoke German Club | 501(c)(7) | 1966 | $97,480 | $24,502 | 2025-08 | |
| Roanoke Star Cycling Inc | Recreation and sports | 501(c)(3) | 2017 | $97,466 | $62,575 | 2025-12 |
| Don Holliday Memorial Golf Tournament Inc | Education | 501(c)(3) | 2024 | $96,506 | $806,578 | 2024-12 |
| Roanoque Baroque | Arts, culture and humanities | 501(c)(3) | 2024 | $94,635 | $67,393 | 2025-07 |
| Samaritan Inn Inc | Mental health and crisis intervention | 501(c)(3) | 1993 | $94,610 | $165,338 | 2025-12 |
| Kimoyo LTD | International, foreign affairs and national security | 501(c)(3) | 2000 | $94,216 | $42,978 | 2025-06 |
| Roanoke Bar Assoc | 501(c)(6) | 1983 | $93,864 | $107,459 | 2025-06 | |
| Nufocusedx LLC | Human services | 501(c)(3) | 2021 | $93,672 | $49,570 | 2025-10 |
| Roanoke Festival in the Park Inc | Arts, culture and humanities | 501(c)(3) | 2014 | $93,036 | $2,517 | 2023-12 |
| National Ski Patrol System | Public safety, disaster preparedness and relief | 501(c)(3) | 1973 | $91,797 | $337,234 | 2025-06 |
| Roanoke Emergency Medical Service Inc | Health care | 501(c)(3) | 2022 | $89,786 | $450,396 | 2025-06 |
| Cave Spring First Aid & Rescue Squad Inc | Health care | 501(c)(3) | 1992 | $85,404 | $386,233 | 2025-03 |
| Visit Virginias Blue Ridge Foundation | Community improvement and capacity building | 501(c)(3) | 2017 | $85,000 | $68,011 | 2025-12 |
| Local Colors of Western Virginia Inc | Crime and legal-related | 501(c)(3) | 2002 | $82,364 | $53,073 | 2024-12 |
| Cave Spring Recreation Foundation Inc | 501(c)(3) | 1960 | $81,999 | $154,714 | 2025-12 | |
| The Roanoke City Police Association Inc | 501(c)(5) | 1995 | $78,462 | $351,647 | 2026-06 | |
| Southwest Virginia Academy Inc | Recreation and sports | 501(c)(3) | 2001 | $78,214 | $18,723 | 2026-06 |
| Roanoke Gospel Outreach Center Inc | Religion-related | 501(c)(3) | 2005 | $76,737 | $808,108 | 2025-12 |
| Greater Southwest Athletic Association | Recreation and sports | 501(c)(3) | 2007 | $76,278 | $92,984 | 2024-12 |
| Roanoke Regional Chamber of Commerce Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2017 | $76,129 | $83,213 | 2024-12 |
| Virginia Association of Centers for Independent Living | Human services | 501(c)(3) | 2001 | $75,082 | $105,736 | 2024-12 |
| International Association of Fire Fighters | 501(c)(5) | 1959 | $74,047 | $103,157 | 2025-12 | |
| Roanoke County Farm Bureau Inc | 501(c)(5) | 1971 | $72,470 | $537,679 | 2025-12 | |
| Little League Baseball Inc | 501(c)(3) | 1967 | $71,780 | $64,033 | 2025-09 | |
| Commonwealth Uniserv | 501(c)(5) | 1978 | $71,703 | $69,649 | 2025-08 | |
| Aaf Roanoke Inc | Arts, culture and humanities | 501(c)(3) | 2016 | $69,958 | $28,558 | 2025-06 |
| Northside Band Boosters | 501(c)(3) | 1986 | $69,539 | $15,211 | 2025-12 | |
| Roanoke Symphony Foundation 708 Dominion Bank Building | Arts, culture and humanities | 501(c)(3) | 1983 | $66,783 | $1.9 million | 2025-06 |
| Blue Ridge Institute for Theological Education | Religion-related | 501(c)(3) | 2018 | $65,500 | $76,028 | 2025-12 |
| Virginia Congress of Parents and Teachers | 501(c)(3) | 1985 | $62,669 | $132,148 | 2025-06 | |
| Roanoke Foundation for Downtown Inc | Community improvement and capacity building | 501(c)(3) | 1993 | $62,580 | $359,303 | 2025-06 |
| Walking On Water Inc | Human services | 501(c)(3) | 2022 | $62,209 | $4,571 | 2025-12 |
| Giving Back Society | Human services | 501(c)(3) | 2016 | $61,595 | $29,184 | 2025-12 |
| Dr E G Gill Blue Ridge Lions Sight Foundation Inc | 501(c)(3) | 1975 | $60,744 | $701,119 | 2025-06 | |
| Youth Sports Inc | Recreation and sports | 501(c)(3) | 2003 | $58,341 | $12,615 | 2023-12 |
| Jubal A Early Preservation Trust | Arts, culture and humanities | 501(c)(3) | 1995 | $57,305 | $1.7 million | 2024-12 |
| Roanoke Council of Garden Clubs Inc | Environment | 501(c)(3) | 1963 | $57,018 | $1 million | 2026-02 |
| Noah Christian Community Center Angels of Hope Outreach Ministry Inc | Youth development | 501(c)(3) | 2006 | $53,334 | $22,896 | 2024-12 |
| Shriners International | 501(c)(10) | 1940 | $53,300 | $97,547 | 2025-12 | |
| Patrick Henry High School Band Boosters Inc | 501(c)(3) | 1986 | $52,719 | $39,396 | 2025-05 | |
| One Positive Alkie Fund | Health care | 501(c)(3) | 2023 | $52,536 | $3,262 | 2025-07 |
| Cosmopolitan Club of Roanoke Foundation Incorporated | 501(c)(3) | 1968 | $51,842 | $6,999 | 2024-12 | |
| USA Softball of Central Virginia Incorporated | Recreation and sports | 501(c)(7) | 2022 | $51,306 | $13,863 | 2024-12 |
| Lighthouse Transformation Church of God Inc | Religion-related | 501(c)(3) | 2008 | $51,000 | $23,250 | 2025-12 |
| Creative Therapy Care | Human services | 501(c)(3) | 2014 | $50,839 | $313,497 | 2025-12 |
| Roanoke Diversity Center | Human services | 501(c)(3) | 2012 | $50,555 | $24,858 | 2025-12 |
| Advertising Federation of the Roanoke Valley Inc | 501(c)(6) | 1982 | $50,274 | $34,206 | 2025-06 | |
| Roanoke Valley Charity Car Show Committee Inc | Diseases, disorders and medical disciplines | 501(c)(3) | 1991 | $47,502 | $5,123 | 2024-12 |
| Virginia Lions Eyeglass Recycling Inc | Health care | 501(c)(3) | 1994 | $47,469 | $154,610 | 2025-06 |
| National Association of Benefits and Insurance Professionals SW Va | Community improvement and capacity building | 501(c)(6) | 2024 | $45,495 | $46,118 | 2026-06 |
| Roanoke Hokie Foundation Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1997 | $45,142 | $73,023 | 2024-12 |
| Virginia Society for Healthcare Human Resources Administration | Health care | 501(c)(6) | 2005 | $43,156 | $15,154 | 2024-12 |
| Elevate Performing Company Inc | Arts, culture and humanities | 501(c)(3) | 2016 | $42,996 | $6,715 | 2025-12 |
| Lishys Gift | Health care | 501(c)(3) | 2019 | $38,838 | $106,458 | 2025-12 |
| Fathers for the Fatherless | Human services | 501(c)(3) | 2013 | $38,317 | $12,872 | 2025-12 |
| Shriners International | 501(c)(10) | 1940 | $37,706 | $124,432 | 2025-12 | |
| E3 Endeavors | Human services | 501(c)(3) | 2017 | $36,829 | $134,009 | 2025-12 |
| Commonwealth Cigar Club LLC | 501(c)(7) | 2009 | $36,688 | $592 | 2024-12 | |
| Turn the Page | Human services | 501(c)(3) | 2014 | $35,680 | $26,599 | 2025-12 |
| Greater Roanoke Valley Development Foundation | 501(c)(6) | 1963 | $34,441 | $1.4 million | 2025-06 | |
| Ahala Childrens Rights Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2007 | $34,273 | $24,440 | 2025-12 |
| 185 Afge Council | 501(c)(5) | 2014 | $30,948 | $40,777 | 2025-12 | |
| Down Syndrome Association of Roanoke | 501(c)(3) | 1992 | $29,352 | $69,479 | 2025-09 | |
| Virginia Collaborative Professionals Inc | Community improvement and capacity building | 501(c)(6) | 2009 | $28,826 | $21,903 | 2024-12 |
| Hollins Communication Research Institute | Social science | 501(c)(3) | 1973 | $27,609 | $27,611 | 2026-06 |
| Old Southwest Inc | 501(c)(3) | 1982 | $27,304 | $77,461 | 2025-01 | |
| Shriners International | 501(c)(10) | 1940 | $24,081 | $37,827 | 2025-12 | |
| The Roanoke Law Foundation | Education | 501(c)(3) | 1998 | $23,701 | $352,362 | 2025-12 |
| Alpha Phi Alpha Fraternity Alpha Kappa Lambda Chapter | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2019 | $19,773 | $1 | 2024-12 |
| Shriners International | 501(c)(10) | 1940 | $19,538 | $35,310 | 2025-12 | |
| Twelve Foundation | Mental health and crisis intervention | 501(c)(3) | 2024 | $15,731 | $14,580 | 2024-12 |
| Virginia Society for Clinical Social Workers Inc | 501(c)(6) | 2021 | $13,103 | $21,065 | 2025-12 | |
| National Association of Benefits & Ins Prof Va CHP | Community improvement and capacity building | 501(c)(6) | 2005 | $12,306 | $39,354 | 2026-06 |
| Anchored in Faith Together Inc | Diseases, disorders and medical disciplines | 501(c)(3) | 2020 | $10,910 | $1,461 | 2024-12 |
| Playlist 4 Life Foundation | Mental health and crisis intervention | 501(c)(3) | 2022 | $9,522 | $1 | 2023-12 |
| Roanoke Valley Medical Missions | Health care | 501(c)(3) | 2017 | $8,651 | $6,549 | 2025-12 |
| Carilion Biomedical Institute | Health care | 501(c)(3) | 2002 | $5,815 | $691,732 | 2025-09 |
| Gentle Shepherd Charities Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1995 | $4,632 | $33,463 | 2025-12 |
| Chrysalis Disability Services | Mental health and crisis intervention | 501(c)(3) | 2024 | $3,284 | $3,607 | 2025-12 |
| National Society of the Sons of the American Revolution | 501(c)(3) | 1944 | $3,280 | $22,117 | 2025-12 | |
| The Dyspnea Society | Medical research | 501(c)(3) | 2023 | $3,259 | $16,412 | 2026-04 |
| Marcus M Wilson Scholarship Fund | Education | 501(c)(3) | 2023 | $3,122 | $4,296 | 2025-06 |
| Amvets Ladies Auxiliary Department of Virginia | Public and societal benefit | 501(c)(19) | 2026 | $2,655 | $2,655 | 2025-08 |
| Dr Nancy Meyer Ministries | Education | 501(c)(3) | 2024 | $1,278 | $1,318 | 2025-12 |
| Scott Hill Foundation Inc | 501(c)(3) | 1990 | $1,059 | $125,197 | 2025-01 | |
| Battle Buddy Wellness Inc | Animal-related | 501(c)(3) | 2024 | $10 | $10 | 2025-12 |
| Roanoke Valley Housing Corporation | Housing and shelter | 501(c)(3) | 1997 | $8 | $73,953 | 2023-12 |
| 1441 Tactical Athlete Program Inc | Crime and legal-related | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| 216 12TH St NW Foundation Inc | Education | 501(c)(3) | 2007 | $0 | $0 | 2025-12 |
| 24TH Virginia Volunteer Infantry Regiment | Arts, culture and humanities | 501(c)(3) | 1991 | $0 | $0 | 2025-12 |
| 3 Balloons | Human services | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| 345TH Bomb Group Association | Arts, culture and humanities | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| 95TH Rifles 1St Battalion Reenactors Inc | 501(c)(3) | 2021 | $0 | $0 | 2025-12 | |
| Aarons Mission | Religion-related | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Abundant Grace Outreach Ministries Inc | Religion-related | 501(c)(3) | 1998 | |||
| Acts 2 Inc | Youth development | 501(c)(3) | 2002 | $0 | $0 | 2025-12 |
| Against the Grain Interdenominational Ministries | Religion-related | 501(c)(3) | 2022 | $0 | $0 | 2026-05 |
| Agape Free Methodist Church | 501(c)(3) | 1958 | ||||
| Aglow International | 501(c)(3) | 1973 | $0 | $0 | 2025-12 | |
| Al Pollard Memorial Foundation | Education | 501(c)(3) | 2006 | $0 | $0 | 2025-12 |
| Al-Rauf Foundation Inc | Food, agriculture and nutrition | 501(c)(3) | 2026 | |||
| Alec Project Inc | Human services | 501(c)(3) | 2025 | |||
| All Inmates Lives Matter Inc | Human services | 501(c)(3) | 2021 | $0 | $0 | 2023-12 |
| Alleghany Education Association | 501(c)(5) | 1978 | $0 | $0 | 2026-06 | |
| Alliance for Health & Biotech Workf Orce Development | Health care | 501(c)(3) | 2026 | $0 | $1 | 2025-12 |
| Alliance of Divine Love Inc | 501(c)(3) | 1977 | ||||
| Alliance of Divine Love Inc | 501(c)(3) | 1977 | ||||
| Alliance of Divine Love Inc | 501(c)(3) | 1977 | ||||
| Alma Ensemble | Arts, culture and humanities | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| Alternative Arts Inc | Arts, culture and humanities | 501(c)(3) | 2022 | $0 | $0 | 2024-12 |
| American Association of University Women | 501(c)(4) | 2010 | $0 | $0 | 2025-06 | |
| American Buddhist Church Development Fund | Religion-related | 501(c)(3) | 2025 | $0 | $0 | 2025-03 |
| American Guild of Organists | 501(c)(3) | 1955 | $0 | $0 | 2025-06 | |
| American Inns of Court Foundation | 501(c)(3) | 1986 | $0 | $0 | 2025-06 | |
| American Legion | 501(c)(19) | 1946 | $0 | $0 | 2025-12 | |
| American Legion | 501(c)(19) | 1946 | $0 | $0 | 2025-12 | |
| American Legion Post 0248 | Public and societal benefit | 501(c)(19) | 2020 | $0 | $0 | 2025-12 |
| Amvets | Mutual and membership benefit | 501(c)(19) | 1945 | $0 | $0 | 2025-08 |
| Amvets | Philanthropy, voluntarism and grantmaking foundations | 501(c)(19) | 1945 | $0 | $0 | 2025-08 |
| Anchor of Hope Community Center | 501(c)(3) | 1955 | ||||
| Ancient Free & Accepted Masons of Virginia | 501(c)(10) | 1972 | $0 | $0 | 2024-12 | |
| Ancient Free & Accepted Masons of Virginia | 501(c)(10) | 1972 | $0 | $0 | 2025-12 | |
| Ancient Free & Accepted Masons of Virginia | 501(c)(10) | 1972 | $0 | $0 | 2023-12 | |
| Ancient Free & Accepted Masons of Virginia | 501(c)(10) | $0 | $0 | 2025-12 | ||
| Ancient Order of Hibernians in America | Mutual and membership benefit | 501(c)(8) | 1945 | $0 | $0 | 2024-12 |
| Art On 1St | Arts, culture and humanities | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Art Project Roanoke Inc | Human services | 501(c)(3) | 2025 | |||
| Arts Recreation & Commerce Inc | Human services | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| As-Salam Islamic Center Inc | Religion-related | 501(c)(3) | 2019 | |||
| Association of Fundraising Professionals | 501(c)(3) | 1987 | $0 | $0 | 2023-12 | |
| Association of Medical Device Service Organizations | Community improvement and capacity building | 501(c)(6) | 2018 | $0 | $0 | 2025-12 |
| Association of Pool and Spa Professionals-Central Chapter Inc | Mutual and membership benefit | 501(c)(6) | 2015 | $0 | $0 | 2025-12 |
| Aware Foundation | Human services | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Back Creek Baptist Fellowship | 501(c)(3) | 1993 | ||||
| Bailey Wildlife Foundation | 501(c)(3) | 1988 | $2.3 million | 2025-12 | ||
| Baptist Home for Southwest Virginia Inc | 501(c)(3) | 1978 | ||||
| Begin Foundation Inc | Education | 501(c)(3) | 2019 | $0 | $0 | 2024-12 |
| Behavioral Health Navigators Center Incorporation | Mental health and crisis intervention | 501(c)(3) | 2014 | $0 | $0 | 2025-12 |
| Beholdbegold | Human services | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Belmont Christian Church | 501(c)(3) | 1951 | 2011-12 | |||
| Benevolent Order of the Dragonfly Lodge 007 | Mutual and membership benefit | 501(c)(8) | 2025 | |||
| Bent Mountain Volunteer Fire Department Incorporated | Public safety, disaster preparedness and relief | 501(c)(3) | 2015 | $0 | $0 | 2025-12 |
| Bethany Christian Church | 501(c)(3) | 1951 | ||||
| Betty Davis Ministries | Religion-related | 501(c)(3) | 2009 | |||
| Bhutanese Community in Roanoke Virginia | Arts, culture and humanities | 501(c)(3) | 2012 | $0 | $0 | 2025-12 |
| Bible & Backpack Drive | Youth development | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Blessing Bag Program | Human services | 501(c)(3) | 2017 | $0 | $0 | 2025-12 |
| Blue Knights Motorcycle Club | Community improvement and capacity building | 501(c)(10) | 2014 | $0 | $0 | 2025-12 |
| Blue Ridge Baseball Club | Recreation and sports | 501(c)(3) | 2025 | |||
| Blue Ridge Chapter of the American Institute of Architects | Community improvement and capacity building | 501(c)(6) | 2016 | $0 | $0 | 2024-12 |
| Blue Ridge Masonry Association Inc - A Chapter of the Va Masonry Asso | Community improvement and capacity building | 501(c)(3) | 2023 | $0 | $0 | 2024-12 |
| Blue Ridge Region Porsche Club of America Inc | 501(c)(7) | 1987 | $0 | $0 | 2025-12 | |
| Blue Ridge Scouting History Inc | Arts, culture and humanities | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Blue Ridge Soccer League | Recreation and sports | 501(c)(3) | 2015 | $227 | 2026-06 | |
| Bonsack Baptist Church | 501(c)(3) | 1968 | ||||
| Bonsack Elementary Pto | Education | 501(c)(3) | 2026 | $13,024 | 2025-05 | |
| Bookbag Santa Inc | International, foreign affairs and national security | 501(c)(3) | 2009 | $0 | $0 | 2024-12 |
| Bosnian Association of Roanoke | Religion-related | 501(c)(3) | 2018 | $0 | $0 | 2024-12 |
| Botetourt County Friends of the Library Inc | Education | 501(c)(3) | 1977 | $0 | $0 | 2025-08 |
| Botetourt Education Association | Mutual and membership benefit | 501(c)(5) | 1978 | $0 | $0 | 2025-12 |
| Boxfit | Youth development | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Bridge Community Development Corporation | Youth development | 501(c)(3) | 2026 | |||
| Brogan Thomas Franklin Live To Learn Scholarship Fund | Education | 501(c)(3) | 2015 | $0 | $0 | 2025-12 |
| Brotherhood of Maintenance of Way Employees | 501(c)(5) | 1966 | $0 | $0 | 2026-03 | |
| Buchanans in the Wild Inc | Religion-related | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Buffalo Soldiers Motorcycle Club of Roanoke | Community improvement and capacity building | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Building Bridges for Humanity | Human services | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Bunn Hollow Farm Animal Rescue | Animal-related | 501(c)(3) | 2024 | $0 | $0 | 2023-12 |
| Bus Riders of Roanoke Advocacy Group | Public and societal benefit | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Business Seed Capital Inc | Community improvement and capacity building | 501(c)(3) | 2024 | |||
| Busk Roanoke | Arts, culture and humanities | 501(c)(3) | 2025 | $0 | $0 | 2024-12 |
| Cabell Brand Center for Interntl Poverty and Resource Studies | International, foreign affairs and national security | 501(c)(3) | 1989 | $0 | $0 | 2026-06 |
| Calvary Baptist Foundation of Roanoke | 501(c)(3) | 1978 | $0 | $0 | 2025-12 | |
| Calvary Chapel of Roanoke | Religion-related | 501(c)(3) | 2004 | |||
| Canie Price Ministries Inc | Religion-related | 501(c)(3) | 2026 | |||
| Capitol Campaigns Inc | Public and societal benefit | 501(c)(3) | 2024 | $0 | $0 | 2024-12 |
| Capt Sean Grimes Pa Student Society | Medical research | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Cartledge Charitable Foundation Inc | 501(c)(3) | 1960 | $114,325 | 2024-08 | ||
| Casa Renacer | Human services | 501(c)(3) | 2015 | $0 | $0 | 2025-12 |
| Catholic Daughters of America 1605 CT St Patrick | 501(c)(3) | 1946 | ||||
| Cavaliers for Education in the Roanoke Valley Inc | Education | 501(c)(3) | 2014 | $0 | $0 | 2025-12 |
| Cave Spring Elite Athletics | Recreation and sports | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Cave Spring Elite Baseball | Recreation and sports | 501(c)(3) | 2025 | $0 | $0 | 2025-07 |
| Cave Spring High School Band Boosters Inc | Education | 501(c)(3) | 2005 | $0 | $0 | 2026-05 |
| Cave Spring High School Parent-Teacher Student Organizatio | Education | 501(c)(3) | 2016 | $0 | $0 | 2026-06 |
| Cave Spring Lions Charities Inc | Human services | 501(c)(3) | 2009 | $0 | $0 | 2025-06 |
| Cave Spring Middle School Parent Teacher Organization | Education | 501(c)(3) | 2024 | $0 | $0 | 2024-06 |
| Cave Spring Softball League Inc | Recreation and sports | 501(c)(3) | 1994 | $0 | $0 | 2025-12 |
| Central and Southwest Virginia Utility Contractors Association | 501(c)(6) | 1988 | $0 | $0 | 2025-12 | |
| Chantal Saint-Fort Gospel Ministry | Religion-related | 501(c)(3) | 2025 | |||
| Chesterman Family Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1997 | $17,233 | 2026-03 | |
| Childrens Advocacy Centers of Virginia | Human services | 501(c)(3) | 2005 | $0 | $412,546 | 2024-12 |
| Chris Askew Memorial Foundation | Community improvement and capacity building | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Chris S Cole Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2025 | |||
| Christ Evangelical Lutheran Church | 501(c)(3) | |||||
| Christ Evangelical Lutheran Church Foundation Inc | 501(c)(3) | 1988 | ||||
| Christ Loves You Ministries | Religion-related | 501(c)(3) | 2016 | |||
| Christ the King Presbyterian Church | 501(c)(3) | 1974 | ||||
| Christian & Missionary Alliance Church of Roanoke Virginia | 501(c)(3) | 1972 | ||||
| Christian Counseling Concepts Inc | Religion-related | 501(c)(3) | 1999 | $0 | $0 | 2025-12 |
| Christopher M Walters Family Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2022 | $35,760 | 2024-12 | |
| Chua Phat Son- Buddha Mountain Center | Religion-related | 501(c)(3) | 2020 | |||
| Church Alive International Inc | Religion-related | 501(c)(3) | 2005 | |||
| Church Women United | 501(c)(3) | 1976 | $0 | $0 | 2024-01 | |
| Church of God | 501(c)(3) | 1972 | ||||
| Church of God and Saints of Christ | 501(c)(3) | 1973 | ||||
| Church of St Peter and St Paul | 501(c)(3) | 1988 | ||||
| Church of the Holy Spirt | Religion-related | 501(c)(3) | 2018 | $0 | $0 | 2021-12 |
| Citylight Church of Roanoke Inc | 501(c)(3) | 1972 | ||||
| Clarence W Hall Foundation | Human services | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| Coalition of Labor Union Women Cluw | Employment | 501(c)(5) | 2015 | $0 | $0 | 2025-12 |
| Column Stage Arts Inc | Arts, culture and humanities | 501(c)(3) | 2026 | |||
| Common Ground Performing Company | Arts, culture and humanities | 501(c)(3) | 2026 | |||
| Commonwealth Coach & Trolley Museum | Arts, culture and humanities | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Commonwealth Search and Rescue | 501(c)(3) | 1989 | $0 | $0 | 2025-06 | |
| Communities for Wildlife Conservati On | Animal-related | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Community Artsreach | Arts, culture and humanities | 501(c)(3) | 2026 | |||
| Community Associations Institute | 501(c)(6) | 1979 | $0 | $0 | 2025-12 | |
| Community of Faith Church | 501(c)(3) | 1974 | ||||
| Computational Psychiatry | Arts, culture and humanities | 501(c)(3) | 2017 | $0 | $0 | 2023-12 |
| Connkidz Inc | 501(c)(3) | |||||
| Continental Societies Inc | 501(c)(3) | 1974 | ||||
| Cornerstone Church | Religion-related | 501(c)(3) | 2005 | |||
| Covenant Business Leaders Inc | Religion-related | 501(c)(3) | 2026 | |||
| Craig County Education Association | 501(c)(5) | 1978 | $0 | $0 | 2026-06 | |
| Creators Collective | Arts, culture and humanities | 501(c)(3) | 2022 | $0 | $0 | 2024-12 |
| Crown of Glory Ministries | Religion-related | 501(c)(3) | 2009 | |||
| Crumpled Thoughts | Human services | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Davids Kingdom Childcare | 501(c)(3) | 1988 | ||||
| Day4naps | Diseases, disorders and medical disciplines | 501(c)(3) | 2019 | $241 | 2025-12 | |
| Delaney Court Civic League | Recreation and sports | 501(c)(3) | 2006 | $0 | $0 | 2024-12 |
| Delta Gamma Fraternity | 501(c)(7) | 1967 | $0 | $0 | 2025-06 | |
| Delta Kappa Gamma Society | 501(c)(6) | 1965 | $0 | $0 | 2026-06 | |
| Delta Sigma Theta Sorority Inc | 501(c)(7) | |||||
| Dermbridge | Health care | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Dharmapala Kadampa Buddhist Center | Religion-related | 501(c)(3) | 2015 | |||
| Diocese of Southwestern Virginia | 501(c)(3) | 1940 | 2013-12 | |||
| Disciples of Christ Fellowship Ministries | Religion-related | 501(c)(3) | 2005 | $0 | $0 | 2024-12 |
| Diversity Camp | Civil rights, social action and advocacy | 501(c)(3) | 2019 | $0 | $0 | 2026-06 |
| Dominion Project International | Education | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Dorothy Koch Family Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2001 | $2 million | 2025-12 | |
| Dotp | Recreation and sports | 501(c)(3) | 2026 | |||
| Dr Beth A Brown Science Foundation | Education | 501(c)(3) | 2012 | $0 | $0 | 2025-12 |
| Ducks On A Mission Inc | Human services | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Duckworth Charitable Foundation Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2002 | $315,289 | 2025-12 | |
| Dwelling Place Church | Religion-related | 501(c)(3) | 2025 | |||
| Edsel Archives Inc | Arts, culture and humanities | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Elshaddai Prison Ministries of Virginia | Religion-related | 501(c)(3) | 2004 | |||
| Embroiderers Guild of America Inc | 501(c)(3) | 1976 |
By cause in Roanoke, VA
- Religion-related 92
- Human services 83
- Education 75
- Recreation and sports 72
- Arts, culture and humanities 70
- Community improvement and capacity building 49
- Health care 47
- Philanthropy, voluntarism and grantmaking foundations 46
- Mental health and crisis intervention 25
- Youth development 22
- Animal-related 19
- Housing and shelter 15
- International, foreign affairs and national security 15
- Public and societal benefit 15
- Environment 13
- Food, agriculture and nutrition 11
- Public safety, disaster preparedness and relief 10
- Mutual and membership benefit 9
- Civil rights, social action and advocacy 9
- Crime and legal-related 7
- Diseases, disorders and medical disciplines 6
- Employment 5
- Medical research 5
Nonprofits in every city of the state
Read from the IRS Exempt Organizations Business Master File, updated by the IRS on October 24, 2026 and rebuilt here every morning. Revenue and assets are from each organization's latest filing as the IRS lists it; the IRS record is the official one. Organizations only: no people are named on these pages.